CN103989698A - Combined preparation for delaying skin aging - Google Patents
Combined preparation for delaying skin aging Download PDFInfo
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- CN103989698A CN103989698A CN201410247491.XA CN201410247491A CN103989698A CN 103989698 A CN103989698 A CN 103989698A CN 201410247491 A CN201410247491 A CN 201410247491A CN 103989698 A CN103989698 A CN 103989698A
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Abstract
The invention provides a combined preparation for delaying skin aging. The combined preparation comprises the following components in parts by weight: 5-100 parts of trinosin, 5-100 parts of vitamin E and 20-500 parts of vitamin C. The combined preparation for delaying skin aging has the beneficial effects of improving skin aging and floppy, spot and pigment deposition, dry and lackluster skin and epidermis traumatic reaction, and does not have toxic or side effects.
Description
Technical field
The present invention relates to the technical field of medical drug, refer more particularly to a kind of combination medicament of delay skin aging.
Background technology
Along with the high speed development in city, the all-environment pollutions such as the radiation of water pollution, atmospheric pollution, sound pollution, electronics, radioactive pollution, cause skin resistance degradation, cause various skin problems;
The cosmetics that use contains heavy metal and hormones, long operating pressure, the skin injury that the improper use of medicine causes, is also one of killer who accelerates skin oxidation, and it can allow skin more intense darkness without light, and dry, mottle also can produce thereupon.
The thickness of skin has obvious change along with the increase at age.People's epidermis is the thickest in the time of 20 years old, and attenuation gradually later can extremely disappear to geratic period granular layer in atrophy, and spine cell shortens life cycle.Epidermis cell karyokinesis increases, therefore melanin also increases, so that old people's the colour of skin mostly is brownish black.Because aged cells is attached to horny layer of epidermis, make skin surface hardening, tarnish.Corium is the thickest in the time of 30 years old, and later gradual change is thin and with atrophy.Subcutaneous fat reduces, and because elastic fibers and collagen fiber change and gradually lose skin elasticity and tension force, further causes cutis laxa and wrinkle generation.
Age growth causes that physiological function is low simultaneously.Sebaceous gland, sweat gland deterioration, perspiration and sebum are got rid of and are reduced, and skin loses gradually in the past gloss and becomes dry.Blood circulation hypofunction is to supplement the nutrition of skin necessity, so the difficult healing of old people's skin wound.
Summary of the invention
The object of the invention is, in order to overcome the deficiencies in the prior art, provides a kind of combination medicament of delay skin aging.
The present invention realizes by above technical scheme:
The invention provides a kind of combination medicament of delay skin aging, the combination medicament of this delay skin aging is grouped into by the one-tenth of following mass ratio: the adenosine triphosphate disodium salt of 5 parts ~ 100 parts, the vitamin E of 5 parts ~ 100 parts and the vitamin C of 20 parts ~ 500 parts.
Preferably, described combination medicament is liquid state, newborn state shape, cream state shape, capsule shape or pill shape.
Preferably, the composition of described adenosine triphosphate disodium salt is 50 parts.
Preferably, the composition of described vitamin E is 50 parts.
Preferably, described ascorbic becoming is 250 parts.
The invention has the beneficial effects as follows: the combination medicament of a kind of delay skin aging provided by the invention, lax for improving treatment skin aging, mottle pigmentation, the effect of dry and astringent tarnish and epidermis injury reaction, and without any side effects.
The specific embodiment
In order to make object of the present invention, technical scheme and advantage clearer, below in conjunction with embodiment, the present invention is further elaborated.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
The embodiment of the present invention provides a kind of combination medicament of delay skin aging, and the combination medicament of this delay skin aging is grouped into by the one-tenth of following mass ratio: the adenosine triphosphate disodium salt of 5 parts ~ 100 parts, the vitamin E of 5 parts ~ 100 parts and the vitamin C of 20 parts ~ 500 parts.
Concrete, described combination medicament is liquid state, newborn state shape, cream state shape, capsule shape or pill shape.The combination medicament of the slow down aging that above embodiment provides can mix each component by consumption, the water preparation being prepared into, and Emulsion, unguentum, cream, gel, one or more of facial film dressing carry out external and embrocate; Or be prepared into injection, one or more of injection freeze-dried powder preparation are used for subcutaneous injection or intramuscular injection; Or making one or more in tablet, capsule, oral liquid mixture takes.
Preferably, the composition of described adenosine triphosphate disodium salt is 50 parts, and the composition of described vitamin E is 50 parts, and preferred, described ascorbic becoming is 250 parts.
Wherein the weight of every part is 1mg, and this combination medicament is comprised of the vitamin C of the adenosine triphosphate disodium salt of 5mg ~ 100mg, the vitamin E of 5mg ~ 100mg and 20mg ~ 500mg.
Adenosine triphosphate wherein (Adenosine triphosphate is called for short ATP).The structure of ATP molecule is to write a Chinese character in simplified form into A-P ~ P ~ P, and wherein A represents adenosine, and P represents phosphate group ,～represent a kind of special chemical bond, be called energy-rich phosphate bond, during energy-rich phosphate bond fission, a large amount of energy can discharge.ATP can be hydrolyzed, and in fact this refer to the hydrolysis of energy-rich phosphate bond in ATP molecule.The energy discharging during energy-rich phosphate bond hydrolysis reaches 30.54kJ/mol, ATP is a kind of high-energy phosphate compound in cell thus.
Adenosine triphosphate (ATP) is the coenzyme extensively existing in body, take inosine monophosphate, IMP as substrate, the energy-rich compound making through the technology of biofermentation, adenosine triphosphate is the direct sources of the movable institute of in-vivo tissue cell all life energy requirement, be described as " the molecule currency " of intracellular energy, store and transmit chemical energy, protein, fat, the synthetic of sugar and nucleotide all needs it to participate in, can impel reparation and the regeneration of the various cells of body, strengthen cell metabolic activity, ATP forms cyclic adenosine monophosphate (cAMP) through adenylate cyclase enzyme catalysis, it is intracellular bioactive substance, the many metabolic processes of cell are had to important regulating action.Treatment various diseases is all had to stronger specific aim, so adenosine triphosphate (ATP) plays very important effect in delay skin aging and skin repair process, indispensable.
Vitamin E wherein (Vitamin E) is a kind of fatsoluble vitamin, claims again tocopherol, is one of topmost antioxidant.Tocopherol can promote sex hormones secretion, and man's motility of sperm and quantity are increased; Make woman's estrogen Enrichment, improve fertility, slow down aging, effectively reduces the generation of wrinkle, the appearance retaining youth.Protection skin is avoided the injury of ultraviolet and pollution, reduces the deposition of cicatrix and pigment; The healing of accelerated in wounds.Vitamin E is coated in can play on the face to moisten and remove pox and prints, and the oral administration and externally used effect that can play speckle dispelling.The natural protective barrier of skin can be repaired and consolidate to natural Vitamin E, pins skin moisture, provides deep layer from inside to outside to nourish, and transforms thick matter skin, makes that skin keeps moistening for a long time, light, water be tender soft and smooth.
It can also promote regeneration and the vigor of human body cell, postpones the ageing process of cell.In addition, can also promote the utilization of human body to vitamin A; Can play synergism with vitamin C, the health of protection skin, reduces occurrence of skin infections; Collagen fiber in skin and elastic fibers are had to " moistening " effect, thereby improve and safeguard the elasticity of skin; Can promote the blood circulation in skin, make skin obtain sufficient nutrition and moisture, to maintain the tender and gloss of skin; Also can suppress the formation of pigmented spots, senile plaque, reduce facial wrinkles and pure white skin, prevent and treat acne.
Vitamin C wherein (L-AA) has melanin in the skin of decomposition, prevention pigmentation, prevents and treats chloasma, freckle generation, makes skin keep the function of pure white delicacy, and has the effect that promotes wound healing, strong blood vessel and skeleton.Vitamin C can strengthen chemotaxis and the deformability of neutrophilic granulocyte, improves sterilizing ability.For skin, vitamin C has following several important function:
1, promote collagen protein synthesis
Vitamin C is the essential thing of manufacturing collagen protein, and collagen protein is the main composition that forms corium.If collagen protein synthesis is obstructed, except skin can produce wrinkle, injured skin be difficult for restoring, the support of blood vessel Ye Huiyin peripheral organization reduces and breaks hemorrhagely, produces purpura.Because the Vitamin C content in aging skin reduces gradually, therefore can produce the problems referred to above.
2, antioxidation, protection skin are not subject to uv damage
Skin can be subject to ultraviolet, smoking and other chemistry, physical property injury, form free free radical, these free radicals can cause destruction, the collagen protein degeneration of cell to produce aging wrinkle variation, even cause Cellular immunity suppression, abnormal differentiation, form skin carcinoma.Vitamin C is potent antioxidant, can capture, in and the free radical in skin, prevent that skin is subject to ultraviolet infringement.Therefore vitamin C can be described as again " Intradermal sunscreen ", although can not absorb or intercept ultraviolet, can in corium, produce the effect of protectiving ultraviolet injury.
3, move back melanin white-skinned face function
Vitamin C produces by vat black pigment and check melanin, can reach the established speckle of desalination and pigmentation, also can improve skin colour.Often be used to clinically whitening treatment.
In addition, vitamin C is to regulating blood circulation of human body, promotion organism metabolism, the overall immunity that improves human body, protection Skin Cell and skin elasticity all to benefit.It is the good auxiliary treatment medicine for the treatment of dermatosis.
In order conveniently to understand the medicament combination of the delay skin aging that the present embodiment provides, with specific embodiment, describe below.
Embodiment mono-:
Adenosine triphosphate disodium salt (ATP) effective content is 30mg every day, and vitamin E (tocopherol) effective content is 50mg every day, and vitamin C (L-AA) effective content is 100mg every day
Embodiment bis-:
Adenosine triphosphate disodium salt (ATP) effective content is 100mg every day, and vitamin E (tocopherol) effective content is 200mg every day, and vitamin C (L-AA) effective content is 500mg every day
Embodiment tri-:
Adenosine triphosphate disodium salt (ATP) effective content is 5mgmg every day, and vitamin E (tocopherol) effective content is 5mg every day, and vitamin C (L-AA) effective content is 20mg every day
Embodiment tetra-:
Adenosine triphosphate disodium salt (ATP) effective content is 50mg every day, and vitamin E (tocopherol) effective content is 100mg every day, and vitamin C (L-AA) effective content is 250mg every day.
Above embodiment takes by consumption single dose or order, or by consumption, each component is mixed, the water preparation being prepared into, and Emulsion, unguentum, cream, gel, one or more of facial film dressing carry out external and embrocate; Or be prepared into injection, one or more of injection freeze-dried powder preparation are used for subcutaneous injection or intramuscular injection; Or making one or more in tablet, capsule, oral liquid mixture takes.
Adenosine triphosphate disodium salt (ATP) can be buied the standard medicines such as adenosine triphosphate disodium salt sheet or tribiofosfor injection easily by ripe commercial sources, effective dosage ranges is 5mg to 100mg every day, preferable range is 30mg to 50mg every day, with single dose or multiple dose, use, preferably once-a-day, preferred oral.
Vitamin E can be buied the standard medicines such as vitamin E soft capsule or vitamin E injection easily by ripe commercial sources, effective dosage ranges is 5mg to 200mg every day, preferable range is 20mg to 100mg every day, with single dose or multiple dose, use, preferably once-a-day or one day twice, preferred oral or external are embrocated.
Vitamin C can be buied the standard medicines such as VITAMIN C TABLET or vitamin C injection easily by ripe commercial sources, effective dosage ranges is 20mg to 500mg every day, preferable range is 100mg to 150mg every day, with single dose or multiple dose, use, preferably once-a-day, preferred oral or intramuscular injection.
By the routine observation of 8 weeks, following the tracks of 152 routine skin aginges or the impaired examination of epiderm skin receptor, in use, to contain adenosine triphosphate disodium salt (ATP) effective content be 5mg---100mg every day, vitamin E (tocopherol) effective content is 5mg---200mg every day, vitamin C (L-AA) effective content is to find to have obvious skin aging and the impaired state of epidermis (data are in Table 1) of improving of 100% ratio in the situation of compositions of 20mg-500mg every day.
Table 1:
Beneficial effect:
The invention reside in the adenosine triphosphate disodium salt of jointly using is provided, vitamin E, the application of vitamin C in the subgroup of improving cutis laxa fold patient.
The invention reside in the adenosine triphosphate disodium salt of jointly using is provided, vitamin E, the application of vitamin C in the subgroup of improving mottle pigmentation patient.
The invention reside in the adenosine triphosphate disodium salt of jointly using is provided, vitamin E, the application of vitamin C in the subgroup of improving dry and astringent matt patient.
The invention reside in the adenosine triphosphate disodium salt of jointly using is provided, vitamin E, the application of vitamin C in the subgroup of improving epidermis injury reaction patient.
Above 152 routine skin aginges or the impaired examination of epiderm skin receptor one or two people are intersected simultaneously and are suffered from different syndromes, therefore there is the result of number double counting in statistical table 1.
Therefore, according to above different preferred implementation, the present invention relates to adenosine triphosphate disodium salt, vitamin E, described in vitamin C, to be used for improving treatment skin aging lax for medicine, mottle pigmentation, the effect of dry and astringent tarnish and epidermis injury reaction, and in preferred dose is used, without any side effects.
These are only preferred embodiment of the present invention, not in order to limit the present invention, all any modifications of doing within the spirit and principles in the present invention, be equal to and replace and improvement etc., within all should being included in protection scope of the present invention.
Claims (5)
1. a combination medicament for delay skin aging, is characterized in that, this combination medicament is grouped into by the one-tenth of following mass ratio: the adenosine triphosphate disodium salt of 5 parts ~ 100 parts, the vitamin E of 5 parts ~ 100 parts and the vitamin C of 20 parts ~ 500 parts.
2. the combination medicament of delay skin aging according to claim 1, is characterized in that, described combination medicament is liquid state, newborn state shape, cream state shape, capsule shape or pill shape.
3. the combination medicament of delay skin aging according to claim 2, is characterized in that, the composition of described adenosine triphosphate disodium salt is 50 parts.
4. the combination medicament of delay skin aging according to claim 3, is characterized in that, the composition of described vitamin E is 50 parts.
5. the combination medicament of delay skin aging according to claim 4, is characterized in that, described ascorbic becoming is 250 parts.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410247491.XA CN103989698A (en) | 2014-06-06 | 2014-06-06 | Combined preparation for delaying skin aging |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410247491.XA CN103989698A (en) | 2014-06-06 | 2014-06-06 | Combined preparation for delaying skin aging |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1503655A (en) * | 2001-04-13 | 2004-06-09 | ��V��ҩ��ʽ���� | Sugar intake promoters |
| CN1679608A (en) * | 2005-02-03 | 2005-10-12 | 北京阜康仁生物制药科技有限公司 | Compound preparation of inosine, triphosphoadenosine and vitamin C and use thereof |
| CN101026965A (en) * | 2004-06-25 | 2007-08-29 | 费诺森股份有限公司 | Compositions suitable for treating cutaneous signs of aging |
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- 2014-06-06 CN CN201410247491.XA patent/CN103989698A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1503655A (en) * | 2001-04-13 | 2004-06-09 | ��V��ҩ��ʽ���� | Sugar intake promoters |
| CN101026965A (en) * | 2004-06-25 | 2007-08-29 | 费诺森股份有限公司 | Compositions suitable for treating cutaneous signs of aging |
| CN1679608A (en) * | 2005-02-03 | 2005-10-12 | 北京阜康仁生物制药科技有限公司 | Compound preparation of inosine, triphosphoadenosine and vitamin C and use thereof |
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Application publication date: 20140820 |
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