CN103976891B - A kind of composition and method of making the same repaired for face - Google Patents
A kind of composition and method of making the same repaired for face Download PDFInfo
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- CN103976891B CN103976891B CN201410171066.7A CN201410171066A CN103976891B CN 103976891 B CN103976891 B CN 103976891B CN 201410171066 A CN201410171066 A CN 201410171066A CN 103976891 B CN103976891 B CN 103976891B
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Abstract
The invention provides a kind of compositions of repairing for face, it comprises each component of following mass percent: EGF lyophilized powder 0.01-1%, SOD0.01-5%, bioactive peptide 0.1-5%, allantoin 0.01-2%, surplus is water, wherein active component liposome embedded or capsule of nano parcel all separately before combination.The active ingredients of said composition is individually got up with transport vehicle parcel or embedding, skin corium or shallow skin corium is arrived by the transport of transport vehicle, promote the metabolism of cell, growth, proliferation and differentiation, scavenging free radicals, harmful substance etc., improve the problems such as dim mute, dark yellow, the hydropenia of skin, aging, sensitivity.
Description
Technical field
The present invention relates to cosmetic technical field, be specifically related to a kind of compositions of repairing for face, and the preparation method of said composition.
Background technology
Skin is the outermost organ of human body; it covers whole body; be made up of epidermis, corium, subcutaneous tissue three layers; protection human body is avoided being subject to external mechanical, physical property, chemical or physiological invasion and attack; remain the stable of human internal environment; skin also participates in the metabolic process of human body simultaneously, expresses the beauty treatment of people and old and feeble mark especially.
And skin impaired have very many factors, there are extraneous physical factor, inherited genetic factors, biological factor, health factor, iatrogenic factors etc., as excessive ultraviolet radiation can make skin that irreversible damage occurs, aging and become coarse, pigmentation etc., supercool, overheated, excessive mechanical irritation all can have an impact to skin simultaneously, makes skin impaired.Under the comprehensive function of various factors, result in the hydropenia of skin, the problem such as dark yellow, lax, responsive, old and feeble, obscure, causing skin can't bear the heavy load, and becomes very fragile.
Cosmetics kind is in the market too much, composition is failed to understand; in addition consumer's improper use; be easy to the damage causing skin; as excessively used the product of destratum corneum; and the result that horny layer is excessively peeled off, horny layer can be made to lose protectiveness, not only cannot resist the injury (as ultraviolet, the temperature difference etc.) of physical factor; also cannot resist the chemokines be covered with in air, skin is as easy as rolling off a log because of weak sensitization.Dermal layer of the skin cell metabolism is vigorous, free circulation of the blood, when it is subject to under-supply etc. the damage of free radical, heavy metal, nutrient substance, especially, during dermal layer of the skin damage, general nutrient substance carries out the reparation of skin because the problems such as molecular size range are difficult to arrive skin corium by skin surface.
Summary of the invention
Technical problem to be solved by this invention is for above the deficiencies in the prior art, a kind of compositions of repairing for face is provided, the active ingredients of said composition is individually got up with transport vehicle parcel or embedding, skin corium or shallow skin corium is arrived by the transport of transport vehicle, promote the metabolism of cell, growth, proliferation and differentiation, scavenging free radicals, harmful substance etc., improve the problems such as dim mute, dark yellow, the hydropenia of skin, aging, sensitivity.
The technical solution adopted in the present invention is:
A kind of compositions of repairing for face, said composition comprises each component of following mass percent: EGF lyophilized powder 0.01-1%, SOD0.01-5%, bioactive peptide 0.1-5%, allantoin 0.01-2%, surplus is water, wherein active component (EGF lyophilized powder, SOD, bioactive peptide, allantoin) liposome embedded or capsule of nano parcel all separately before combination, thus preparation there is ultra micro capsule structure can the repairing activity material of Transdermal absorption.
Described bioactive peptide is the one in Argireline, algal active peptide, micromolecule collagen polypeptide.
EGF lyophilized powder can repair horny layer, strengthens the thickness of skin, the stratum corneum gets thinner caused decortication thing and the bad composition of the middle appearance that makes in the past to apply some make up, red blood streak expose, fragile, easily rubescent, the phenomenon such as to itch have super good repair.But EGF lyophilized powder can not directly be applied in client's face, re-use after needing it to mix with solvent.
SOD plays dual function to skin, on the one hand it can to promote that collagen protein is formed appropriately crosslinked; On the other hand, it can be used as effective free radical scavenger, prevents skin aging, keeps submissive smooth, perpetual youth.SOD can also stablize collagen protein and elastin laminin, thus makes skin high resilience.Due to ultraviolet injury, human skin can accelerate old and feeble and wrinkling, and SOD can assist protection skin from ultraviolet damage; can scavenging free radicals effectively; block the generation of elastoser, and suppress it active, thus improve the health status of skin from inside.Life-time service, can nourishes rough skin, reduces dermatosis and wrinkle.SOD is the strongest effective antioxidant of scavenging free radicals, and its oxidation resistance is ascorbic 20 times, 50 times of vitamin E, and other antioxidants are incomparable especially for the specificity of its scavenging free radicals, high efficiency.Adhere to use SOD can while dispelling free radical endocrine regulation, prevent skin from occurring mottle.
Bioactive peptide is the active factors gone out from extraction and isolation such as animals and plants, the protein polypeptide closed by two or more amino acid chain, the deep enough Skin Cell of this active polypeptide energy, supplement Skin Cell nutrient fast, direct activation and skin nutrition cell, reach deep layer reparation, promote effect of cellular metabolism, active cell vigor.
Allantoin can make cell proliferation be formed rapidly to make epidermal area, reaches and repairs skin, the effect of induction neoplastic skin skin care exquisiteness, makes chafing, anaphylaxis, Zou Wen and aging, be full of cracks obtain good reparation and recover normal effect.
We know, the increase that composition often planted by cosmetics all likely changes certain physics or the chemical characteristic of whole system.The present invention takes the lead in that EGF lyophilized powder, SOD, bioactive peptide, allantoin these four kinds are had the combinations of substances of repair together, by proportioning rational between each material, make each material in said composition can play its effect well, and synergism is good, thus effectively realize promoting the metabolism of cell, growth, proliferation and differentiation, scavenging free radicals, harmful substance etc., improve the problems such as dim mute, dark yellow, the hydropenia of skin, aging, sensitivity.
The product form of described compositions is cream frost or liniment or facial film or emulsion or toner/smoothing toner or cleansing milk.
The present invention also provides the preparation method of the above-mentioned compositions for face reparation further, it comprises the following steps: each raw material taking recipe ingredient, by all independent to EGF lyophilized powder, SOD, bioactive peptide, allantoin with liposome embedded or capsule of nano parcel, then 60-65 DEG C of water-bath constant temperature 30min is placed in, after water-bath terminates, each component is mixed, slowly stir also Temperature fall and, to room temperature, obtain the compositions of repairing for face.
The present invention more payes attention to the research of the Transdermal absorption of cosmetic industry composition, makes the effective active composition of cosmetics by skin, and arrives not same-action skin layer and play various effect.Compared with prior art, the present invention has following remarkable advantage and beneficial effect:
(1) liposome technology and capsule of nano technology is adopted, active ingredient encases or embedding are got up, by the transhipment of these transport vehicle, promote that active factors enters skin skin corium, promote at the bottom of the growth of skin cell, Differentiation, scavenging activated oxygen, strengthening flesh, strengthen the defensive ability/resistance ability of skin, thus fundamentally repair skin, scavenging free radicals and harmful substance, promote the formation of collagen fiber, reticular fiber, elastic fiber, regulate the generation of collagen protein, recover smooth, tender, the elasticity of skin;
(2) adopt Transdermal absorption movement system, substantially increase the horny layer of active component particularly biomacromolecule material or high molecular polymer through rate, transdermal transfer rate is high;
(3) liposome technology and the two kinds of technology realization embeddings to active component of capsule of nano technology are adopted, than being used alone a kind of embedding techniques, embedding Du Genggao, embedding better effects if;
(4) active component is wrapped or embeds, keep apart with extraneous oxygen, dust particle etc., the object of prolection composition can be reached, ensure the stability of active component, prevent that it is oxidized, destruction etc., and each active component wraps up separately or embeds, avoid the probability of having an effect each other, system stability is good, prevents oxidized prior art compared to by adding antioxidant, do not need additionally adding of stable elements, cost is relatively lower;
(5) composition components of the present invention's face reparation is simple, and formula is reasonable, and cooperative effect is good, and reparation effect is good.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further described in detail.Iting is noted that following illustrating is all exemplary, being intended to the invention provides further instruction.Except as otherwise noted, all Science and Technology terms that the present invention uses have the identical meanings usually understood with the technical field of the invention personnel.
Embodiment 1:
The present embodiment is for repairing equilibrium water, and its formula is:
Preparation process:
(1) embed 0.02gEGF lyophilized powder and 0.02gSOD respectively with liposome, obtain EGF liposome and SOD liposome, be then placed in 60 DEG C of water-bath constant temperature 30min;
(2) wrap up 0.05g Argireline and 0.1g allantoin respectively with capsule of nano, obtain Argireline microcapsule and allantoin microcapsule, be then placed in 60 DEG C of water-bath constant temperature 30min;
(3) aminoacid, glycerol, propylene glycol, hydroxyethyl-cellulose is taken, add water appropriate, stirring lower dissolving is swelling to clear and bright, (1) item and (2) item are slowly added in above-mentioned lysate respectively, then add essence, antiseptic (germall BP) stirs, supply water to 100.0g, must equilibrium water be repaired.
Embodiment 2:
The present embodiment is repair cream, and its formula is:
Preparation process:
(1) embed 0.1gEGF lyophilized powder and 0.15gSOD respectively with liposome, obtain EGF liposome and SOD liposome, be then placed in 60 DEG C of water-bath constant temperature 30min;
(2) wrap up 0.2g algal active peptide and 0.2g allantoin respectively with capsule of nano, obtain algal active peptide microcapsule and allantoin microcapsule, be then placed in 60 DEG C of water-bath constant temperature 30min;
(3) oil phase raw material mixed and be heated to 70 DEG C, Aqueous Phase Raw Material is mixed and heated to 60 DEG C, oil phase is added in aqueous phase, (1) item and (2) item are added in aqueous phase respectively simultaneously, stirring and emulsifying, add essence after cooling and antiseptic stirs, obtain repair cream.
Embodiment 3:
The present embodiment is repair latex, and its formula is:
Preparation process:
(1) embed 0.05gEGF and 0.15g micromolecule collagen polypeptide respectively with liposome, obtain EGF liposome and micromolecule collagen polypeptide liposome, be then placed in 60 DEG C of water-bath constant temperature 30min;
(2) wrap up 0.05gSOD and 0.15g allantoin respectively with capsule of nano, obtain SOD microcapsule and allantoin microcapsule, be then placed in 60 DEG C of water-bath constant temperature 30min;
(3) Aqueous Phase Raw Material is mixed and heated to 65 DEG C-70 DEG C, being mixed by oil phase raw material and being heated to 70 DEG C-80 DEG C makes it melt evenly, oil phase and aqueous phase are added in emulsion tank respectively, (1) item and (2) item are added in emulsion tank respectively simultaneously, maintain 70 DEG C, homogenizing 10min-30min, is cooled to about 40 DEG C, add essence and antiseptic stirs, obtain repair latex.
Embodiment 4:
The present embodiment is for repairing facial film, and its formula is:
Preparation process:
(1) embed 0.01gEGF and 0.01gSOD respectively with liposome, obtain EGF liposome and SOD liposome, be then placed in 60 DEG C of water-bath constant temperature 30min;
(2) wrap up 0.05g Argireline and 0.1g allantoin respectively with capsule of nano, obtain Argireline microcapsule and allantoin microcapsule, be then placed in 60 DEG C of water-bath constant temperature 30min;
(3) hyaluronic acid, glycerol, propylene glycol, carboxymethyl cellulose, hydroxyethyl-cellulose is taken, add water appropriate, stirring lower dissolving is swelling to clear and bright, (1) item and (2) item are slowly added in above-mentioned lysate respectively, then add essence, antiseptic stirs, supply water to 100.0g, obtain reparation facial mask essence, then carry out fill, packaging, obtain reparation facial film.
The raw material that embodiment is used, unless otherwise indicated, is the commercially available prod that applicable cosmetics use.
The above embodiment of the present invention can not be used for limiting the present invention to explanation of the present invention, and any change in the implication suitable with claims of the present invention and scope, all should think to be included in the scope of claims.
Claims (3)
1. a compositions of repairing for face, it is characterized in that each component comprising following mass percent: EGF lyophilized powder 0.01-1%, SOD0.01-5%, bioactive peptide 0.1-5%, allantoin 0.01-2%, surplus is water, wherein active component liposome embedded or capsule of nano parcel all separately before combination; Described bioactive peptide is the one in Argireline, algal active peptide, micromolecule collagen polypeptide.
2. a kind of compositions of repairing for face according to claim 1, is characterized in that: described compositions is cream frost or liniment or facial film or emulsion or toner/smoothing toner or cleansing milk.
3. the preparation method of a kind of compositions for face reparation described in the arbitrary claim of claim 1-2, it is characterized in that comprising the following steps: each raw material taking recipe ingredient, by all independent to EGF lyophilized powder, SOD, bioactive peptide, allantoin with liposome embedded or capsule of nano parcel, then 60-65 DEG C of water-bath constant temperature 30min is placed in, after water-bath terminates, each component is mixed, slowly stir also Temperature fall and, to room temperature, obtain the compositions of repairing for face.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410171066.7A CN103976891B (en) | 2014-04-25 | 2014-04-25 | A kind of composition and method of making the same repaired for face |
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| CN201410171066.7A CN103976891B (en) | 2014-04-25 | 2014-04-25 | A kind of composition and method of making the same repaired for face |
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| CN103976891A CN103976891A (en) | 2014-08-13 |
| CN103976891B true CN103976891B (en) | 2016-01-27 |
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Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104337734A (en) * | 2014-10-22 | 2015-02-11 | 广东幸美化妆品股份有限公司 | Restoring facial cleanser and preparation method thereof |
| CN105310945A (en) * | 2015-12-15 | 2016-02-10 | 钟苏 | Skin repair mask cream and preparation method thereof |
| CN105560160B (en) * | 2016-03-16 | 2018-08-17 | 广州市科玮生物技术有限公司 | A kind of facial mask liquid and preparation method thereof containing chitosan |
| CN106265130A (en) * | 2016-09-29 | 2017-01-04 | 防城港市港口区高创信息技术有限公司 | A kind of compositions for skin repair and preparation method thereof |
| CN107213043A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of lemonene peach additive and preparation method thereof |
| CN107213046A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of alkanet cosmetic composition and preparation method thereof |
| CN107213045A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of elder composition and preparation method thereof |
| CN107213080A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of aloe additive and preparation method thereof |
| CN107213044A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of white birch cosmetic composition and preparation method thereof |
| CN107213047A (en) * | 2016-12-20 | 2017-09-29 | 林彩霞 | A kind of hairyvein agrimony composition and preparation method thereof |
| CN112006964A (en) * | 2019-05-31 | 2020-12-01 | 广州北斗生物科技有限公司 | Preparation method and application of microcapsule-coated polypeptide substance with skin care effect |
| CN112675046B (en) * | 2020-12-31 | 2022-02-15 | 华南理工大学 | Almond polypeptide hair care nano micelle and preparation method thereof |
| CN117427201B (en) * | 2023-12-20 | 2024-03-15 | 辽宁帝东医药生物工程有限公司 | Antibacterial wound dressing capable of promoting healing |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1112828A (en) * | 1994-05-30 | 1995-12-06 | 乌力吉 | Face care cream containing extract of Chinese soft shelled turtle and snail |
| CN1875916A (en) * | 2006-04-27 | 2006-12-13 | 广州市采诗化妆品有限公司 | A whitening moisturizing composition |
| CN102366383B (en) * | 2011-09-26 | 2012-12-26 | 佛山科学技术学院 | Marine organism functional cosmetic for nourishing skin around eyes |
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