CN103961552A - Externally applied unguent for treating bedsore and preparation method thereof - Google Patents
Externally applied unguent for treating bedsore and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an externally applied unguent for treating bedsore and a preparation method thereof. The externally applied unguent for treating bedsore is characterized by comprising the following traditional Chinese medicine raw materials by weight: 15g of cooked rhubarb, 30g of dried alum, 30g of calcined gypsum, 10g of sanguis draconis, 6g of notoginseng powder, 30g of honeycomb, 15g of elephant hide, 20g of lithospermum, 15g of earthworm, 15g of bletilla, 15g of caulis spatholobi, 20g of calcined fossil fragments, 20g of clove, 2g of musk, 15g of cassia twig, 20g of indigo naturalis, 30g of aloe, 10g of folium artemisiae argyi, 15g of poria cocos, 15g of cortex moutan, 10g of pollen pini, 15g of astragalus membranaceus, normal dosage of sesame oil, 5g of membrane of hen egg and 2500u of heparin for injection. Except the membrane of hen egg, the traditional Chinese medicine raw materials are grinded into powder; the sesame oil is added to mix into paste; the paste is put into a perforated aluminum specimen box and then the perforated aluminum specimen box is put into a pot for steaming; after cooling, the 5g of powdery membrane of hen egg is added to mix for after use. During the use, the 2500u of heparin is added to mix uniformly for external application. The externally applied unguent for treating bedsore is used for 91 bedsore patients, wherein healing occurs on 46 patients, excellence occurs on 22 patients, effectiveness occurs on 18 patients, ineffectiveness occurs on 4 patients, the total effective rate is 94.5% and no complications such as local skin allergy and the like are caused.
Description
Technical field
The present invention relates to a kind of external-applied ointment and preparation method for the treatment of decubital ulcer.
Background technology
Decubital ulcer (pressure ulcer) is due to the long-term pressurized of local organization, continuous ischemia, anoxia, malnutrition occur and causes a kind of disease of tissue fester's necrosis.Be more common in the long-term bedridden patients such as paraplegia, chronic expendable illness, large-area burns and degree of depth stupor.Decubital ulcer is one of common clinically complication, and according to incompletely statistics, inpatient's incidence rate is 5.1 %～32.1%.Often there is clinically wound surface protracted course of disease, expand deepen, infect increase the weight of, skin-grafting or flap Yu Shou district be difficult to healing, the even situation such as flap necrobiosis, and easily cause infection, once deterioration meeting brings great misery to patient, even septicemia occur and cause death.
Summary of the invention
The object of this invention is to provide a kind of external-applied ointment and preparation method for the treatment of decubital ulcer.
For achieving the above object, the technical solution used in the present invention is:
A kind of external-applied ointment for the treatment of decubital ulcer, it is characterized in that: its Chinese medicine proportioning raw materials is: Radix Et Rhizoma Rhei 15g, dried Alumen 30g, Gypsum Fibrosum Preparatum 30g, Sanguis Draxonis 10g, Radix Notoginseng powder 6g, Nidus Vespae 30g, Corium elephatis 15g, Radix Arnebiae (Radix Lithospermi) 20g, Pheretima 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Caulis Spatholobi 15g, Os Draconis (calcined) 20g, Flos Caryophylli 20g, Moschus 2g, Ramulus Cinnamomi 15g, Indigo Naturalis 20g, Aloe 30g, Folium Artemisiae Argyi 10g, Poria 15g, Cortex Moutan 15g, Pollen Pini 10g, Radix Astragali 15g, be equipped with Oleum Sesami, Membrana Follicularis ovi 5g, the injection heparin 2500u of conventional amount used.
A method of preparing the external-applied ointment of described treatment decubital ulcer, is characterized in that: above all medical herbs, except Membrana Follicularis ovi, are pulverized, and add Oleum Sesami to reconcile into paste, puts into aluminum box with holes, and upper pot steams 30 minutes, adds powdery Membrana Follicularis ovi 5g after cooling, stand-by after being in harmonious proportion.External after adding heparin 2500u to be in harmonious proportion evenly when use.
The external-applied ointment that uses the present invention to treat decubital ulcer is treated patients with bedsore 91 examples, recovery from illness 46 examples, and effective 22 examples, effective 18 examples, invalid 4 examples, total effective rate is 94.50%, occurs without complication such as local skin allergy.With the matched group comparison that does not use Chinese medicinal ointment, difference has statistical significance (P<0.05).This Chinese medicinal ointment can obviously promote the healing of decubital ulcer, and clinical efficacy is remarkable.Ointment be the one that is mixed of powder and solid oils evenly, fine and smooth, semisolid external preparation; deeply effect is stronger, can protect skin, prevents extraneous physics, the stimulation of chemical factor to skin; the skin of can moistening, protection wound surface and hinder the evaporation of moisture of skin.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described.
Embodiment
Raw material of Chinese medicine proportioning of the present invention:
Radix Et Rhizoma Rhei 15g, dried Alumen 30g, Gypsum Fibrosum Preparatum 30g, Sanguis Draxonis 10g, Radix Notoginseng powder 6g, Nidus Vespae 30g, Corium elephatis 15g, Radix Arnebiae (Radix Lithospermi) 20g, Pheretima 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Caulis Spatholobi 15g, Os Draconis (calcined) 20g, Flos Caryophylli 20g, Moschus 2g, Ramulus Cinnamomi 15g, Indigo Naturalis 20g, Aloe 30g, Folium Artemisiae Argyi 10g, Poria 15g, Cortex Moutan 15g, Pollen Pini 10g, Radix Astragali 15g, be equipped with Oleum Sesami, Membrana Follicularis ovi 5g, the injection heparin 2500u of conventional amount used.
Preparation technology:
All medical herbs, except Membrana Follicularis ovi, are pulverized above, add Oleum Sesami to reconcile into paste, put into aluminum box with holes, and upper pot steams 30 minutes, add powdery Membrana Follicularis ovi 5g after cooling, stand-by after being in harmonious proportion.External after adding heparin 2500u to be in harmonious proportion evenly when use.
Using method: after conventional debridement, with Chinese medicine lotion for external use external application affected part, a situation arises to treat rear observation in 4 weeks two groups of Wound healing rates, healing time, complication.
Pharmacology analysis:
Radix Et Rhizoma Rhei hardship, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Rush down and exert oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.
Dried Alumen is irregular crystalline solid, and matter is hard and crisp, easily smashes.Feeble QI, taste is micro-sweet and puckery." detailed outline ": " tell lower sputum drink phosphorus, dampness removing toxic substances, chases after saliva, hemostasis analgesic therapy, meat is disliked in erosion, and raw good meat, controls carbuncle furuncle swollen, malignant boil, epilepsy, subcutaneous ulcer disease, relieving bowels, all diseases of ability to speak eyes, brave dog snakes and scorpions hundred insect bites."
Gypsum Fibrosum Preparatum is white powder or loose block, and matter is soft, frangible, and odorless is lightly seasoned.Sweet in the mouth, property are pungent, puckery, cold.Attach to the lung and stomach meridians.Cure mainly removing dampness, granulation promoting, sore, hemostasis.External treatment ulcer being unable to heal, eczema pruritus, burn due to hot liquid or fire, traumatic hemorrhage
Sanguis Draxonis, " book on Chinese herbal medicine covers bamboo fish trap ": " acrid in the mouth is salty, and property gas is flat, slightly poisonous." enter the heart, liver, spleen channel.Promoting blood circulation to remove blood stasis for oral administration, analgesic therapy, external hemostasia and promoting granulation, sore.
Radix Notoginseng powder, " book on Chinese herbal medicine converges and says ": sweet and slightly bitter taste, property is flat, nontoxic.Enter liver, stomach, large intestine channel.Be known as there is significant blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain effect, there is the good reputation of " Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) ", " southern part of the country SHENCAO ".
Nidus Vespae sweet in the mouth is flat, returns stomach warp, enters Yangming Channel, liver, lung two warps.Have detoxicating and killing parasites, effect of wind-expelling pain-stopping, for sore swollen toxin.This product removing mass of assaulting fortified position is the product that surgery is conventional.This product light weight and property are apt to away alter, can wind-expelling pain-stopping.
Corium elephatis, " book on Chinese herbal medicine is newly organized ": " sweet in the mouth, gas is flat, nontoxic." enter bladder meridian.Cure mainly granulation promoting, sore.Do not close up for a long time for skin infection.
Radix Arnebiae (Radix Lithospermi) bitter in the mouth, cold in nature, cure mainly and invigorate blood circulation, heat clearing away, removing toxic substances, burn, eczema, erysipelas, carbuncle and ulcer.Modern study proves that Radix Arnebiae (Radix Lithospermi) has inhibitory action to staphylococcus aureus, suppuration bacterium, escherichia coli.And can accelerate epithelial growth and treatment burn.Topical application can promote wound healing.
Pheretima acrid in the mouth, temperature.Main Function is dispelling, collateral-activating, arresting convulsion, eliminating stagnation, controls paralysis due to windstroke, severe and migratory arthralgia pain, wind-phlegm infantile convulsion, scrofula, malignant boil etc.
Pseudobulbus Bletillae (Rhizoma Bletillae) bitter in the mouth, sweet, puckery, cold nature, returns lung, liver, stomach warp.Cure mainly astringing to arrest bleeding, detumescence and promoting granulation, sore swollen toxin, chapped skin.
Caulis Spatholobi bitter but slightly sweet taste, warm in nature, returns liver, the heart, kidney channel.There is relaxing muscles and tendons to promote blood circulation, effect of the waist gonalgia, rheumatic arthralgia, numb limbs and tense tendons, the compatibilities such as the normal and Radix Astragali, Radix Salviae Miltiorrhizae.
Os Draconis (calcined) sweet in the mouth adstringency, flat, there is hemostasis astringing intestine to stop diarrhea, effect of promoting tissue regeneration and ulcer healing.
Flos Caryophylli, " Kaibao Bencao ": " acrid in the mouth, temperature, nontoxic." enter stomach, spleen, kidney channel.Cure mainly trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, ringworm.
Moschus is warm in nature, nontoxic, bitter in the mouth, enters the heart, spleen, Liver Channel.There is the function of having one's ideas straightened out, warding off dirty, dredging collateral, scattered silt.Cure mainly attacked by pestiferous factors unhappiness, trusted subordinate's sudden pain, traumatic injury, swollen ulcer drug.
Ramulus Cinnamomi nature and flavor acrid, sweet, warm, enter lung, the heart, urinary bladder channel, are to cure mainly the conventional drugs for dispelling internal cold of interior cold, have effect of complement sun, promoting blood circulation, warming the spleen and stomach.
Indigo Naturalis nature and flavor are salty-cold, have heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Cure mainly: epidemic febrile disease intenseness of heat, skin ulcer is swollen, erysipelas." Kaibao Bencao " recorded: all poison of drug of principal solution, the poison such as the deposited herpes simplex of rubbing, evil swell, incised wound, hematochezia, Serpentis dog.
Aloe, containing compositions such as phenols, aloin, organic acid, has killing action to some antibacterial, fungus, virus.There is ulcer, promote wound healing, stimulating cellular growth and anastalsis.
Folium Artemisiae Argyi acrid in the mouth, hardship, warm in nature, nontoxic, return spleen, liver, kidney channel.Pharmacological research shows that Folium Artemisiae Argyi is a kind of medicine of broad-spectrum antibacterial antiviral, and it has inhibition and lethal effect to a lot of virus and antibacterial, has warming the meridian for stopping bleeding, effect of dispersing cold for relieving pain
Poria sweet in the mouth, light, property is flat, GUIXIN, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, spleen invigorating, the effect of calming the nerves.Can strengthen the lymphocytic cytotoxic effect of T, and therefore activate the immunological surveillance system of body to tumor.
Cortex Moutan cures mainly clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, and carbuncle sore tumefacting virus, falls and flutters the pain of injury." herbal classic ": " main cold and heat, except the hard blood stasis of disease stays house the intestines and stomach, settling five organs, treats carbuncle skin ulcer."
Pollen Pini comprises the nutrient substance such as multiple proteins, aminoacid, nucleic acid, monosaccharide, polysaccharide.Warm in nature, sweet in the mouth, has benefiting QI and nourishing blood, a QI invigorating of dispeling the wind, removing dampness, the effects such as hemostasis.Control all skin ulcers wet rotten, wound hemorrhage.
Radix Astragali sweet in the mouth, slightly warm in nature, returns lung, spleen, liver, kidney channel.Skin infection is not closed up for a long time, have the effect of promoting tissue regeneration and wound healing.Cave in for skin infection not diabrosis for a long time, have the diabrosis of promotion and limitation effect.
Oleum Sesami, Chinese medicine is thought: nature and flavor are sweet, cool, has effect of loosening bowel to relieve constipation, removing toxic substances and promoting granulation.According to recording in Compendium of Material Medica: " have moisturize, the merit of removing toxic substances, pain relieving, detumescence.”
Membrana Follicularis ovi, the traditional Chinese medical science calls " Membrana Follicularis ovi " the inner membrance of Ovum crusta Gallus domesticus.This product is the fibrous connective tissue of height collagenzation, the fibrous tissue parallel with surface by densification forms, stick decubital ulcer surface, thin and soft because of it, occupancy is strong, a little less than antigenicity, a kind of good natural biological dressing, for wound surface provides maintenance film and the barrier that one deck is new, wound surface is temporarily sealed, the chance that reduces moisture evaporation and pollute and infect.
Heparin is a kind of anticoagulant, is the glycosaminoglycan being alternately formed by connecting by two kinds of polysaccharide, has the effects such as anticoagulant, infection, promotion revascularization, is conducive to tissue repair and re-epithelialization.Energy alleviating pain, anticoagulant, inflammation-inhibiting reaction, promotion revascularization, recover local blood confession, improves immunity of organisms.Topical application heparin is a kind of effective means for the treatment of decubital ulcer.
pharmacodynamics statistical analysis:
The clinical efficacy of Chinese medicine lotion for external use treatment decubital ulcer of the present invention.
Method: 182 routine patients with bedsore are pressed to the simple randomization method of dividision into groups, be divided into treatment group 91 examples, matched group 91 examples.After the conventional debridement for the treatment of group, with Chinese medicine lotion for external use external application of the present invention affected part, matched group gives conventional debridement and changes dressings.A situation arises to treat rear observation in 4 weeks two groups of Wound healing rates, healing time, complication.
Result: treatment group 46 examples of fully recovering, effective 22 examples, effective 18 examples, invalid 5 examples, total effective rate is 94.50%, without complication such as local skin allergy; Matched group 20 examples of fully recovering, effective 18 examples, effective 22 examples, invalid 31 examples, total effective rate is 65.93%.Two groups of comparing differences have significant (P<0.05).Conclusion: Chinese medicine lotion for external use of the present invention (certainly intending name: decubital ulcer more) can obviously promote bedsore wound healing, evident in efficacy, has no adverse reaction, and clinic is applied.
By 182 routine decubital ulcer patients clinical treatments, in 91 routine patient's topical therapeutics, adopt the Chinese medicine lotion for external use treatment of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, putrefaction-removing granulation-promoting, relatively clinical efficacy is remarkable with matched group, has promoted the healing of decubital ulcer.Now be reported as follows:
1. clinical data
1.1 object of study: 182 routine patients with bedsore.Meet in primary disease, Western medicine diagnose standard.After patient's informed consent, voluntarily tested and sign Informed Consent Form.
1.1.1 by the routine patient of sex 182, press the simple randomization method of dividision into groups with the ratio of 1:1, be divided into treatment group and matched group.Details sees the following form 1
Table 1
Two groups of patients divide into groups aspect sex, learn and process by statistics, and no significant difference (P>0.05), has comparability.
1.1.2 age-based, the course of disease, decubital ulcer area, 182 routine patients press the simple randomization method of dividision into groups with the ratio of 1:1, are divided into treatment group and matched group.Details sees the following form 2:
Table 2
Two groups of patients learn processing by statistics at age, the course of disease, initial wound surface area, and no significant difference (P>0.05), has comparability.
1.1.3 by protopathy, the ratio of 182 routine patient 1:1 is pressed the simple randomization method of dividision into groups, is divided into treatment group and matched group.Details sees the following form 3:
Table 3
Two groups of patients learn by statistics processing aspect protopathy, and no significant difference (P>0.05), has comparability.
1.1.4 by the site of pathological change of decubital ulcer, 182 routine patients press the simple randomization method of dividision into groups with the ratio of 1:1, are divided into treatment group and matched group.Details sees the following form 4:
Table 4
Two groups of patients learn by statistics processing aspect site of pathological change, and no significant difference (P>0.05), has comparability.
1.2 diagnostic criterias: 1. Western medicine diagnose standard and by stages: the various skin decubital ulcers that cause that weigh wounded, through not healing person of more than 1 month wound surface of conventional therapy.Decubital ulcer is by stages: the I phase: pressurized position is rubescent; The II phase: pressurized position is rubescent, swelling, scleroma, visible blister forms sometimes, is deep to festering of skin corium; The III phase: cutaneous necrosis, exposes fatty tissue; The IV phase: adipose tissue necrosis, expose muscular tissue; The V phase: muscular tissue necrosis, expose periosteum, produce osteomyelitis and suppurative arthritis.
The assessment of wound should by observe wound surface performance and wound surface antibacterial culturing judge whether be infected wound wound by stages: a mummification necrosis phase: wound surface shows as the alternate slough of HUANGBAI(sic) or black crust; The b inflammatory reaction phase: wound surface has a large amount of inflammatory exudates; C granulation trophophase: wound surface is cerise; D epithelium forms the phase: wound surface pinkiness, and wound shoals; 2. tcm diagnosis standard: local color is red from the beginning of pain after often first itching, and erosion transfers rapidly decubital ulcer to.Decubital ulcer differs in size, and is greyish white or kermesinus, surface or with yellow pus tongue, pus is dirty smelly unpleasant.Sick decubital ulcer edge for a long time thickening is raised, and surrounding color of the leather darkness overflows and swells or with eczema, after closing in, easily repeatedly show effect.
1.3 observation index: 1. Wound healing rate: wound healing degree=(original wound surface area-wound surface area does not heal)/original wound surface area × 100%; 2. complication rate: local skin allergy, suppress and the allergic symptom such as breathe heavily.
2. Therapeutic Method
After the debridement for the treatment of group conventional surgical, skin ulcer face is evenly coated with Chinese medicine lotion for external use of the present invention, then coated with antiseptic gauze, uses immobilization with adhesive tape.Change dressings every day 1 time.Matched group, after conventional surgical debridement, then coated with antiseptic gauze, uses immobilization with adhesive tape.Change dressings every day 1 time.Nursing accomplishes that duty is stood up, diligent cleaned, diligent massage, diligently arrange, diligently change, duty hands over to the next shift
3. the standard of curative effect evaluation
Formulate with reference to " People's Republic of China's Chinese medicine industry standard traditional Chinese medical science disease Standardization of diagnosis and curative effect ".Clinical recovery: wound surface heals completely; Effective: wound surface obviously dwindles, >=75%, clinical symptom disappearance; Effective: wound surface dwindles, <75% or >=25%, clinical symptoms improve; Invalid: wound surface dwindles, <25%, even expands, and clinical symptoms is not improved.
4. therapeutic outcome
4.1 decubital ulcer healing rate statistical tables:
Two groups of patient's comparisons, treatment group effective percentage is 94.50%, apparently higher than matched group 65.93%.Difference has significant (P<0.05).
4.2 decubital ulcer healing time statistical tables:
Two groups of patient's comparisons, treatment group healing time is starkly lower than matched group.Difference has significant (P<0.05).
4.3 complication: the allergic symptoms such as the irritated pruritus of local skin do not appear in treatment group, also do not find uncomfortable in chest, suppress and the complication such as symptom such as allergy such as breathe heavily.
5. statistical analysis:
Adopt SPSS 13.0 for Windows Chinese editions to carry out chi-square criterion to observed result. decubital ulcer healing rate and healing time have statistical significance (χ 2=6.160, P < 0.05).
6. discuss
" medical science source and course " thought: " method of surgery, the heaviest external treatment." " infections section outline " point out: " skin infection is for sick, and outside sending out and seeing, external treatment medicine is particularly important.All light shallow cards, specially rely on external treatment, admittedly can receive merit; And dangerous large infections, You Bilai external treatment is proper, is use alternately, this surgeon." decubital ulcer mostly occurs in sacrococcygeal region, hip and rotor portions.Location tables is shallow, and local application can make the through sick institute of the efficacy of a drug more can play a role, therefore local application becomes main Therapeutic Method, removing the necrotic tissue and promoting granulation method can promote decubital ulcer slough to come off and granulation tissue growth.
External-applied ointment treatment patients with bedsore 91 examples of application for the treatment of decubital ulcer of the present invention, recovery from illness 46 examples, effective 22 examples, effective 18 examples, invalid 4 examples, total effective rate is 94.50%, occurs without complication such as local skin allergy.With the matched group comparison that does not use Chinese medicinal ointment, difference has statistical significance (P<0.05).This Chinese medicinal ointment can obviously promote the healing of decubital ulcer, and clinical efficacy is remarkable.Ointment be the one that is mixed of powder and solid oils evenly, fine and smooth, semisolid external preparation; deeply effect is stronger, can protect skin, prevents extraneous physics, the stimulation of chemical factor to skin; the skin of can moistening, protection wound surface and hinder the evaporation of moisture of skin.
The traditional Chinese medical science thinks that " decubital ulcer is that to hinder be also skin ulcer, hinders qi depression to blood stasis, and the stasis of blood is obstructed, stagnation of QI and blood may bring about pain; The stagnation of QI temperature is long-pending, the long-pending rotten pus and blood of temperature ... " by as above method, Chinese medicine is added to taste and make various preparations, with blood circulation promoting and blood stasis dispelling, granulation promoting pain relieving and cure the wound; With clearing away heat and cooling blood, putrefaction-removing granulation-promoting and control skin ulcer; Consolidate the principle treatment decubital ulcers such as granulation promoting, have clinically significant curative effect.This clinical research shows, Chinese medicine lotion for external use of the present invention has obvious anti-inflammation detumescence, removing the necrotic tissue and promoting granulation, the healing of promotion bedsore wound, and clinical efficacy is remarkable, and without obvious adverse reaction, clinic is applied.
Embodiment recited above is described the preferred embodiment of the present invention; not design of the present invention and protection domain are limited; do not departing under the prerequisite of design concept of the present invention; various modification and improvement that in this area, common engineers and technicians make technical scheme of the present invention, all should fall into protection scope of the present invention.
Claims (2)
1. treat the external-applied ointment of decubital ulcer for one kind, it is characterized in that: its Chinese medicine proportioning raw materials is: Radix Et Rhizoma Rhei 15g, dried Alumen 30g, Gypsum Fibrosum Preparatum 30g, Sanguis Draxonis 10g, Radix Notoginseng powder 6g, Nidus Vespae 30g, Corium elephatis 15g, Radix Arnebiae (Radix Lithospermi) 20g, Pheretima 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Caulis Spatholobi 15g, Os Draconis (calcined) 20g, Flos Caryophylli 20g, Moschus 2g, Ramulus Cinnamomi 15g, Indigo Naturalis 20g, Aloe 30g, Folium Artemisiae Argyi 10g, Poria 15g, Cortex Moutan 15g, Pollen Pini 10g, Radix Astragali 15g, be equipped with Oleum Sesami, Membrana Follicularis ovi 5g, the injection heparin 2500u of conventional amount used.
2. prepare a method for the treatment of the external-applied ointment of decubital ulcer described in claim 1, it is characterized in that: above all medical herbs, except Membrana Follicularis ovi, are pulverized, add Oleum Sesami to reconcile into paste, put into aluminum box with holes, upper pot steams 30 minutes, after cooling, add powdery Membrana Follicularis ovi 5g, stand-by after being in harmonious proportion.External after adding heparin 2500u to be in harmonious proportion evenly when use.
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Cited By (5)
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| CN104435728A (en) * | 2014-11-14 | 2015-03-25 | 上海市浦东医院 | External Chinese medicinal ointment for treating bedsores as well as preparation method and application thereof |
| CN105456940A (en) * | 2015-12-30 | 2016-04-06 | 项阳 | External ointment for treating bedsores |
| CN106421396A (en) * | 2016-11-21 | 2017-02-22 | 冯祥柱 | Traditional Chinese medicine ointment with efficacy of tissue regeneration promotion and preparation method of traditional Chinese medicine ointment with efficacy of tissue regeneration promotion |
| CN107375622A (en) * | 2017-08-18 | 2017-11-24 | 黄斌 | A kind of bed sore flesh engendering ointment |
| CN112516256A (en) * | 2020-12-04 | 2021-03-19 | 于海峰 | External powder for treating trauma and preparation method thereof |
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| CN103751544A (en) * | 2014-01-16 | 2014-04-30 | 周红 | Topically applied paste for treating bedsore |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435728A (en) * | 2014-11-14 | 2015-03-25 | 上海市浦东医院 | External Chinese medicinal ointment for treating bedsores as well as preparation method and application thereof |
| CN104435728B (en) * | 2014-11-14 | 2017-10-31 | 上海市浦东医院 | It is a kind of to treat Externally applied Chinese medicine paste of bedsore and its production and use |
| CN105456940A (en) * | 2015-12-30 | 2016-04-06 | 项阳 | External ointment for treating bedsores |
| CN106421396A (en) * | 2016-11-21 | 2017-02-22 | 冯祥柱 | Traditional Chinese medicine ointment with efficacy of tissue regeneration promotion and preparation method of traditional Chinese medicine ointment with efficacy of tissue regeneration promotion |
| CN107375622A (en) * | 2017-08-18 | 2017-11-24 | 黄斌 | A kind of bed sore flesh engendering ointment |
| CN112516256A (en) * | 2020-12-04 | 2021-03-19 | 于海峰 | External powder for treating trauma and preparation method thereof |
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