CN1444967A - Chinese herbal medicine preparation for treating burns - Google Patents

Abstract

A Chinese medicine in the form of ointment of spray for treating burn, scald and sore is prepared from 9 Chinese-medicinal materials including gypsum, calamine, cuttlefish bone, pearl, etc through respectively calcining and parching, pulverizing, proportional mixing, adding vaseline, and stirring. Its advantage is high curative effect.

Description

The Chinese medicine preparation of treatment burn

Technical field:

The invention provides a kind of Chinese medicine preparation for the treatment of burn, belong to the pharmaceutical technology field of Chinese traditional treatment burn and scald disease.

Background technology:

At present, the medicine of existing multiple treatment burn and scald on the market, as: JINGWANHONG RUANGAO etc., but antiinflammatory, healing and analgesic effect for burn wound are not desirable especially, and some can also cause whole body or local anaphylaxis, and be difficult to the prevention and the control ratio of traumatic infection, large-area slightly degree of depth wound surface need be made skin graft and can be healed, cicatrization after the healing is more, and in therapeutic process coating repeatedly, patient is painful big.

Summary of the invention:

The invention provides a kind of Chinese medicine preparation for the treatment of burn, have and relieve the pain rapidly, wound healing is fast, and characteristics such as preventing from scar have overcome the shortcoming of existing treatment burn and scald medicine.

Technical solution of the present invention is as follows: according to the basic principle of China's Chinese medicine treatment burn and scald, with reference to the modern pharmacological research achievement, from motherland's medicine treasure-house, filter out and have hemostasis and anti-inflammation, evacuation of pus is pulled out dried, the closing in granulation promoting, the pure Chinese herb medicine of heat-clearing and toxic substances removing is made externally used paste through the conventional medicament processing procedure.

Medicine of the present invention is made by following raw materials by weight portion:

Gypsum Fibrosum 30～45, Calamina 30～45, Calcitum rubrum 20～35, Ophicalcitum 28～35, Endoconcha Sepiae 10～18, Myrrha 6～10, Olibanum 4～8, Margarita 1～3, Concha Margaritifera 3～6.

Optimum ratio of the present invention is:

Gypsum Fibrosum Preparatum 35, Calamina (calcined and quenched) 35, Calcitum rubrum 28, Ophicalcitum 32, Endoconcha Sepiae 13, Myrrha (parched) 9, Olibanum (parched) 5, Margarita 1.5, calcined Concha Margaritifera 4.3.

Processing procedure is as follows:

It is stand-by that Gypsum Fibrosum, Calamina and Concha Margaritifera are ground into 100～200 order fine powders behind the calcine respectively; It is stand-by that Myrrha, Olibanum are ground into 100～200 order fine powders after the parch respectively; By above-mentioned prescription other medicines are ground into 100～200 order fine powders, the mix homogeneously of all putting together, and adding vaseline is modulated into ointment.

Above-mentioned medicament can also be made said spray of pharmaceutics or water preparation.

Indication: clearing away heat to alleviate pain, blood activating and promoting tissue regeneration.Be used for area and be no more than 10% shallow, dark II ° of burn.Comprise that scald, electric burn, high temeperature chemistry product burn.Various boils.

Using method: wound surface is cleaned with physiological saline solution, after the debridement, medicine evenly is applied on the sterile gauze, and the about 1～2mm of thickness of covering spreads on wound surface, and wrapping is fixing, and the next day changes dressings once.

The present invention is the secret recipe of treatment burn handed down from one's ancestors, is basic the guidance with the theory of Chinese medical science, and the clinical experience in conjunction with for many years forms through choosing.Wherein,

Gypsum Fibrosum, Calamina are monarch drug, the Gypsum Fibrosum acrid-sweet flavor, and property Great Cold, can clearing away heat-fire, external application can be held back skin ulcer by removing dampness, is the key medicine of treatment burn.The Calamina sense of taste is flat, also is the surgical intervention skin infection, can detoxify and have the effect of removing dampness erosion prevention and muscle growing, and two medicines match and can strengthen heat-clearing and toxic substances removing, and removing dampness is held back the effect of skin ulcer.The ministerial drug Calcitum rubrum: acrid in the mouth is salty, and is cold in nature, the energy resolving heat and reducing pathogenic fire, and relieving restlessness is quenched the thirst; Ophicalcitum: sour-acrid taste, property is flat, sour and astringent convergence, Xin Nenghang looses, but the removing stasis to stop bleeding pain, auxiliary monarch drug, heat-clearing and toxic substances removing, removing dampness are held back skin ulcer blood stasis dispersing and deswelling pain relieving granulation promoting.Adjuvant drug Endoconcha Sepiae salty in the mouth, puckery, property are little wet, and external has the dampness hemostasia and promoting granulation to hold back the merit of skin ulcer; The little toil of Olibanum, property is wet, merit be apt to activating blood circulation to dissipate blood stasis, stagnation resolvation blood and then pain only, the muscle life; Myrrha, but eliminating stasis to stop pain detumescence and promoting granulation, three medicines match, and have the effect of dissipating blood stasis for subsidence of swelling pain relieving removing the necrotic tissue and promoting granulation.Margarita, sweet in the mouth, salty, cold in nature, the energy heat-clearing and toxic substances removing, promoting tissue regeneration and ulcer healing is joined Concha Margaritifera, but potentiation.Two medicines share, and can strengthen heat-clearing and toxic substances removing, hold back the effect of creation flesh.More than each medicine mutually 5, play the therapeutic effect of heat-clearing and toxic substances removing, activating blood circulation to dissipate blood stasis, reducing swelling and alleviating pain, removing the necrotic tissue and promoting granulation altogether.

Good effect of the present invention is: preparation is that pure Chinese herbal medicine is made, and toxic and side effects is little, and treating both the principal and secondary aspects of a disease is evident in efficacy, and clinical symptom disappearance is rapid.

For showing the therapeutic effect of medicine of the present invention, selected 132 routine burn and scald patients take medicine of the present invention and treat, and carry out statistical analysis through system's clinical observation and are summarized as follows:

One, diagnostic criteria:

1, area calculates: Chinese rule of Nine, palm test.

2, depth estimation: three degree quarterings.

3, state of an illness classification:

Minor burn: the gross area is at ° burn of the II below 9%.

Moderate burn: the gross area is 10～29%, or III ° of burn surface area is below 10%.

4, Chinese medical discrimination: the flourishing card of fire-toxin, fire-toxin impairment of YIN card, fire-toxin inside fire attack internal organs, the moon

Undermine YANG syndrome, deficiency of both QI and blood, the cloudy stomach that decreases loses card.

Two, curative effect judging standard:

1, clinical cure: wound healing, General Symptoms disappears.

2, produce effects: II ° of skin ulcer face, total wound healing are 90% or more or III ° of skin ulcer face, and the gross area heals more than 50%, the General Symptoms disappearance.

3, effective: II ° of skin ulcer face, total wound healing 50% above III ° total wound healing is more than 30%, and General Symptoms disappears.

4, invalid: do not reach effective standard, traumatic infection fails to control.

Three, curative effect:

Grouping	The example number	14 days healing rates (%)	Healing time (my god)	The VAS scoring
							1 day	5 days	11 days
				The present invention	??76	??77.04±12.59				???16.64±2.48	????3.95±2.48	???1.99±1.80	???0.70±0.80
JINGWANHONG	??56	??59.55±12.59	???20.29±2.37				????3.97±2.85	???2.88±2.50	???1.08±1.08
				The P value		??＜0.001				???＜0.001	????＞0.05	???＞0.05	???＞0.05

Sum up:

The present invention is in treatment burn and scald patient's process; brought into play obviously analgesic effect fast; the prevention of highly significant and control traumatic infection; the speed of molten crust decrustation is fast; the parabiosis tissue there is good protective action; can promote the growth of granulation tissue and epithelial tissue, prevention and minimizing wound healing scar tissue form, and have obtained curative effect preferably.

The specific embodiment:

Embodiment 1

Take by weighing Gypsum Fibrosum 35g, Calamina 35g, Calcitum rubrum 28g, Ophicalcitum 32g, Endoconcha Sepiae 14g, Myrrha 9g, Olibanum 5g, Margarita 1.8g, Concha Margaritifera 4.5g.

It is stand-by that Gypsum Fibrosum, Calamina and Concha Margaritifera are ground into 100～200 order fine powders behind the calcine respectively; It is stand-by that Myrrha, Olibanum are ground into 100～200 order fine powders after the parch respectively; By above-mentioned prescription other medicines are ground into 100～200 order fine powders, the mix homogeneously of all putting together, and adding vaseline is modulated into ointment.Other project should meet 2000 editions ointment projects of Pharmacopoeia of People's Republic of China relevant requirements.

Embodiment 2

Take by weighing Gypsum Fibrosum 45g, Calamina 35g, Calcitum rubrum 25g, Ophicalcitum 40g, Endoconcha Sepiae 12g, Myrrha 13g, Olibanum 4g, Margarita 1.8g, Concha Margaritifera 6g.

It is stand-by that Gypsum Fibrosum, Calamina and Concha Margaritifera are ground into 100～200 order fine powders behind the calcine respectively; It is stand-by that Myrrha, Olibanum are ground into 100～200 order fine powders after the parch respectively; By above-mentioned prescription other medicines are ground into 100～200 order fine powders, the mix homogeneously of all putting together, and adding ethanol aerosol is modulated into spray.Other project should meet 2000 editions spray projects of Pharmacopoeia of People's Republic of China relevant requirements.

Claims (3)

1, a kind of Chinese medicine preparation for the treatment of burn is characterized in that it being the medicine of being made by ratio of weight and the number of copies by following Chinese medicine:

Gypsum Fibrosum Preparatum 30～45, Calamina (calcined and quenched) 30～45, Calcitum rubrum 20～35, Ophicalcitum 28～35,

Endoconcha Sepiae 10～18, Myrrha (parched) 6～10, Olibanum (parched) 4～8, Margarita 1～3, calcined Concha Margaritifera 3～6.

2, Chinese medicine preparation according to claim 1 is characterized in that it being the medicine of being made by ratio of weight and the number of copies by following Chinese medicine:

Gypsum Fibrosum Preparatum 35, Calamina (calcined and quenched) 35, Calcitum rubrum 28, Ophicalcitum 32, Endoconcha Sepiae 13, Myrrha (parched) 9, Olibanum (parched) 5, Margarita 1.5, calcined Concha Margaritifera 4.3.

3,, it is characterized in that said medicament is said ointment, spray, a water preparation on any pharmaceutics according to claim 1,2 described Chinese medicine preparation.