CN103931954B - A kind of for regulating and controlling to repair feed addictive of Intestine of Broiler and preparation method thereof - Google Patents
A kind of for regulating and controlling to repair feed addictive of Intestine of Broiler and preparation method thereof Download PDFInfo
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- CN103931954B CN103931954B CN201410195427.1A CN201410195427A CN103931954B CN 103931954 B CN103931954 B CN 103931954B CN 201410195427 A CN201410195427 A CN 201410195427A CN 103931954 B CN103931954 B CN 103931954B
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- 239000000377 silicon dioxide Substances 0.000 claims description 21
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- PWLNAUNEAKQYLH-UHFFFAOYSA-N butyric acid octyl ester Natural products CCCCCCCCOC(=O)CCC PWLNAUNEAKQYLH-UHFFFAOYSA-N 0.000 claims description 18
- UUIQMZJEGPQKFD-UHFFFAOYSA-N n-butyric acid methyl ester Natural products CCCC(=O)OC UUIQMZJEGPQKFD-UHFFFAOYSA-N 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 17
- 229920001592 potato starch Polymers 0.000 claims description 14
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- 239000007787 solid Substances 0.000 claims description 5
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- 238000010521 absorption reaction Methods 0.000 abstract description 11
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 abstract description 9
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- FERIUCNNQQJTOY-UHFFFAOYSA-M Butyrate Chemical compound CCCC([O-])=O FERIUCNNQQJTOY-UHFFFAOYSA-M 0.000 abstract description 5
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- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Abstract
The present invention relates to a kind of for regulating and controlling to repair feed addictive of Intestine of Broiler and preparation method thereof, belonging to bird breeding technology field.This feed addictive contains the components such as sodium butyrate, butyrate, clostridium butyricum, the enteron aisle that can realize broiler chicken regulates and repairs, enteron aisle height of naps is made to improve about 120%, reduce Intestine of Broiler Crypt depth about 50%, improve V/C, reduce the quantity of Intestine of Broiler harmful bacteria, promote that Intestine of Broiler is grown, improve the absorption of nutriment, improve immunity of meat chickens, make " punishment in advance " and ascites symptoms be solved or improve, improve broiler chicken survival rate, feed digestibility and culture benefit, bring huge economic benefit.By comparing with control group, growth of meat chicken speed after adding this feed addictive, is made to improve 13%; Dead mortality declines 70%; Feedstuff-meat ratio improves 4%; A broiler chicken increases income 0.6 yuan.
Description
Technical field
The present invention relates to a kind of feed addictive and preparation method thereof, particularly relating to a kind of for regulating and controlling to repair feed addictive of Intestine of Broiler and preparation method thereof, belonging to bird breeding technology field.
Background technology
Enteron aisle is the maximum digestive organs of poultry, is the place of absorption and digestion nutrition.Intestinal mucosa layer surface coated with intestinal villus, the food entered in enteron aisle resolves into glucose, amino acid under the effect of various digestive juice, food digestion is absorbed after, residue forms ight soil and is excreted.Once enteron aisle is ill, will Disorder of Digestion and A orption be caused, thus affect the growth of broiler chicken.Research shows, the associating of different virus, different bacterium and other infectiousness or non-infectious cause of disease or interaction, be enough to the intestines problem of bringing out in various degree.Can say that Intestine of Broiler disease is annoying the development of broiler chicken industry always, at present, aborning, the method that feeding antibiotic is added in usual employing prevents such disease, but antibiotic use result in problems, as medicament residue, drug resistance, suprainfection and reduction immunity of organisms etc., its application is very limited.
Therefore, need a kind of new technology of exploitation to regulate and control reparation Intestine of Broiler, stop to use antibiotic, thus avoid by the generation of the problems such as the medicament residue, drug resistance, suprainfection and the reduction immunity of organisms that use antibiotic to bring.
Summary of the invention
Technical problem to be solved by this invention is that the defect overcoming prior art provides a kind of feed addictive for regulating and controlling to repair Intestine of Broiler, this additive is under the prerequisite without harm to animal and human body, can to repair and to reduce Intestine of Broiler impaired, antibiotics additive can be replaced completely, and successful.
Technical problem of the present invention is realized by following technical scheme.
For regulating and controlling to repair a feed addictive for Intestine of Broiler, the component containing following weight portion: sodium butyrate 20 ~ 40, methyl butyrate 90 ~ 110, clostridium butyricum 90 ~ 110, silica 60 ~ 80, modified potato starch 70 ~ 80.
Preferably, the above-mentioned feed addictive for regulating and controlling to repair Intestine of Broiler, the component containing following weight portion: sodium butyrate 30, methyl butyrate 100, clostridium butyricum 100, silica 70, modified potato starch 75.
Sodium butyrate can promote that intestinal mucosa is grown, and repairs mucosal epithelial cells, activated lymphocyte; Adjustment micro ecology of gastrointestinal tract balance, promotes profitable strain propagation; Reduce intestines and stomach pH; Strengthen enteron aisle nospecific immunity, safeguard intestinal health; Have strong synergism with antibiosis, antibacterial growth-promoting effect is obvious.
Clostridium butyricum has four mcroorganism characteristics: one is the propagation and the growth that promote animal intestinal profitable strain, suppresses the growth of harmful bacteria and spoilage organisms in enteron aisle, breeding, corrects enteric flora disturbance, reduce the generation of enterotoxin; Two is can produce the materials such as B family vitamin, vitamin K, amylase in animal intestinal, with health role; Three is main metabolites butyric acid of clostridium butyricum is the histiocytic regeneration of gut epithelium and repairs Major Nutrient material; Four is anaerobism or amphimicrobian bacillus, does not affect by hydrochloric acid in gastric juice, bile acid etc.
Methyl butyrate, sodium butyrate, clostridium butyricum three compositions are mutually promoted, are superposed, and are more conducive to decompositing butyric acid, promote that the growth of enteron aisle and bacterium are balanced each other, and reduce bowel problems and occur, and promote that enteron aisle pH value controls at sour environment, ensure intestinal health.
Another object of the present invention is the preparation method providing this feed addictive.
The above-mentioned preparation method for regulating and controlling to repair the feed addictive of Intestine of Broiler, comprises the following steps:
(1) take the methyl butyrate of recipe quantity, sodium butyrate and silica, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch in step (1) gained mixture and prescription is made the fine granularity material of the spray-dried rear formation 0.2 ~ 0.5mm of wall material, again fine granularity material fully being mixed with the clostridium butyricum of recipe quantity, obtaining the feed addictive for regulating and controlling to repair Intestine of Broiler of the present invention.
Methyl butyrate can reduce its volatilization after silica supports absorption, sodium butyrate can reduce its stink ability and moisture absorption after silica supports bag is processed, methyl butyrate, sodium butyrate are through fully mixing with silica, advantageously play in the guarantee of its content and its effect at enteron aisle, the stability of product be improved significantly, tire more stable.Adding after clostridium butyricum is for minimizing methyl butyrate and sodium butyrate are on bacterium viable count and active impact, is more conducive to it and plays a role at Intestine of Broiler.Modified potato starch good film-forming property, transparency are high is conducive to the stability of feed addictive and the stripping of active ingredient.The fine granularity substance advantageous of 0.2 ~ 0.5mm in the absorption of active ingredient and distribution in vivo, thus can ensure to play effectiveness.
Feed addictive for regulating and controlling to repair Intestine of Broiler of the present invention, the enteron aisle that can realize broiler chicken regulates and repairs, ileum height of naps is made to improve about 120%, reduce broiler chicken ileum Crypt depth about 50%, improve V/C, reduce the quantity of Intestine of Broiler harmful bacteria, promote that Intestine of Broiler is grown, improve the absorption of nutriment, improve immunity of meat chickens, make " punishment in advance " and ascites symptoms be solved or improve, improve broiler chicken survival rate, feed digestibility and culture benefit, bring huge economic benefit.By comparing with control group, growth of meat chicken speed after adding this feed addictive, is made to improve 13%; Dead mortality declines 70%; Feedstuff-meat ratio improves 4%; A broiler chicken increases income 0.6 yuan.
Detailed description of the invention
Below by detailed description of the invention, the invention will be further described, but just understand the present invention for helping, and professional and technical personnel in the field realized or uses the present invention, not forming any restriction to the present invention.
Embodiment 1 preparation for regulating and controlling to repair the feed addictive of Intestine of Broiler of the present invention
Prescription: sodium butyrate 30, butyrate 100, clostridium butyricum 100, silica 70, modified potato starch 75.
Preparation method:
(1) take the methyl butyrate of recipe quantity, sodium butyrate and silica, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch of step (1) gained mixture and recipe quantity is done that wall material is spray-dried forms 0.2mm fine granularity material afterwards, again fine granularity material fully being mixed with the clostridium butyricum of recipe quantity, obtaining the feed addictive for regulating and controlling to repair Intestine of Broiler of the present invention.
Embodiment 2 preparation for regulating and controlling to repair the feed addictive of Intestine of Broiler of the present invention
Prescription: sodium butyrate 20, butyrate 90, clostridium butyricum 90, silica 60, modified potato starch 70.
Preparation method:
(1) take the methyl butyrate of recipe quantity, sodium butyrate and silica, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch of step (1) gained mixture and recipe quantity is done that wall material is spray-dried forms 0.5mm fine granularity material afterwards, again fine granularity material fully being mixed with the clostridium butyricum of recipe quantity, obtaining the feed addictive for regulating and controlling to repair Intestine of Broiler of the present invention.
Embodiment 3 preparation for regulating and controlling to repair the feed addictive of Intestine of Broiler of the present invention
Prescription: sodium butyrate 40, butyrate 110, clostridium butyricum 110, silica 80, modified potato starch 80.
Preparation method:
(1) take the methyl butyrate of recipe quantity, sodium butyrate and silica, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) modified potato starch of step (1) gained mixture and recipe quantity is done that wall material is spray-dried forms 0.3mm fine granularity material afterwards, again fine granularity material fully being mixed with the clostridium butyricum of recipe quantity, obtaining the feed addictive for regulating and controlling to repair Intestine of Broiler of the present invention.
Embodiment 4 comparative example
Two groups are divided by 180 broiler chicken, first group is test group, test group uses basal feed, second group is control group, 0-7 age in days, 7-14 age in days, 14-28 age in days and 28 ages in days-deliver for sale, in the breeding process of this four-stage, the feed addictive for regulating and controlling to repair Intestine of Broiler prepared by the embodiment of the present invention 1 is used in basal feed, its consumption is use 300g in basal feed per ton, is also to use sodium butyrate 30g, butyrate 100g, clostridium butyricum 100g, silica 70g, modified potato starch 75g in basal feed per ton.
Test group and control group, establish 3 repetition groups respectively, each repetition group 30 broiler chicken, and its object is to stability checking, Repeatability is verified.
The Comparative result (duodenum) of test group and control group when table 1 is delivered for sale
The normal configuration of enteron aisle and function are nutriments is weigh the important indicator of enteron aisle digestion and absorption function by the villi height of the basic guarantee of abundant peptic ulcer bleeding, particularly enteron aisle, Crypt depth, intestines wall thickness, V/C and fine hair total surface area.Villi height and cell quantity are significant correlation, and in finger-like fine hair, the height of fine hair is relevant with its enterocyte quantity.When fine hair is elongated, enterocyte increasing number; The villus cell minimizing that fine hair is ripe in short-term, low to the absorbability of nutrient.Crypt depth reflects cellular survival rate, and cell constantly moves from Crypt base to fine hair end, differentiation, with normally coming off of supplementary chorioepithelium.Therefore, crypts can be regarded as the processing factory of fine hair.If this process slows down, the cellular survival rate of base portion reduces, and crypts is shoaled.Crypts shoals and shows that enterocyte maturing rate rises, and absorption function strengthens.Crypts deepens and illustrates that tissue metabolism accelerates and new organization needs to increase, and mean that maintaining desired nutritional increases, animal productiong efficiency declines.V/C reflects the functional status of enteron aisle, and ratio rises, then mucous membrane improves, and digestion and absorption function strengthens, quickening of growing; Ratio declines, and mucous membrane is impaired, and digestion and absorption function reduces.As shown in Table 1, after delivering 42d for sale to broiler chicken compared with control group, test group can make enteron aisle height of naps bring up to about 120%, reduces Intestine of Broiler Crypt depth to about 50%, significantly improve V/C, the quantity of remarkable reduction Intestine of Broiler harmful bacteria, promotes that Intestine of Broiler is grown, improves the absorption of nutriment, and significantly reduced dorking abdominal dropsy generation, make growth of meat chicken speed improve 13%, feedstuff-meat ratio improves 4%, and dead mortality decline 70%, broiler chicken increases income 0.6 yuan.
Above-described embodiment is only for illustrating technical conceive of the present invention and advantage; the present invention also can have other variation; as well known to the skilled person; above-described embodiment only plays the exemplary role in foregoing invention protection domain; for those of ordinary skills; in the protection domain that the present invention limits, also have a lot of conventional deformation and other embodiment, these distortion and embodiment are all by within the protection domain that awaits the reply in the present invention.
Claims (2)
1. one kind for regulating and controlling to repair the feed addictive of Intestine of Broiler, it is characterized in that, it is made up of the component of following weight portion: sodium butyrate 20 ~ 40, methyl butyrate 90 ~ 110, clostridium butyricum 90 ~ 110, silica 60 ~ 80, modified potato starch 70 ~ 80; This preparation method being used for regulating and controlling to repair the feed addictive of Intestine of Broiler comprises the following steps:
(1) take the methyl butyrate of recipe quantity, sodium butyrate and silica, methyl butyrate, sodium butyrate and silica are fully mixed at PLM-65 liquid-solid mixer, mixture is for subsequent use;
(2) by the fine granularity material of the spray-dried rear formation 0.2 ~ 0.5mm of the modified potato starch making wall material of step (1) gained mixture and recipe quantity, again fine granularity material fully being mixed with the clostridium butyricum of recipe quantity, obtaining the feed addictive for regulating and controlling to repair Intestine of Broiler.
2. the feed addictive for regulating and controlling to repair Intestine of Broiler according to claim 1, it is characterized in that, it is made up of the component of following weight portion: sodium butyrate 30, methyl butyrate 100, clostridium butyricum 100, silica 70, modified potato starch 75.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410195427.1A CN103931954B (en) | 2014-05-09 | 2014-05-09 | A kind of for regulating and controlling to repair feed addictive of Intestine of Broiler and preparation method thereof |
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| CN201410195427.1A CN103931954B (en) | 2014-05-09 | 2014-05-09 | A kind of for regulating and controlling to repair feed addictive of Intestine of Broiler and preparation method thereof |
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| CN103931954B true CN103931954B (en) | 2015-09-30 |
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| CN104585509A (en) * | 2015-02-03 | 2015-05-06 | 广东绿生源饲料科技有限公司 | Forage-use granular sodium butyrate and preparation method thereof |
| CN105746905A (en) * | 2016-03-01 | 2016-07-13 | 湖南晶天科技实业有限公司 | Feed additive and preparation method thereof |
| CN109566863A (en) * | 2019-01-18 | 2019-04-05 | 湖北华扬科技发展有限公司 | Feed addictive and its preparation method and application |
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| CN101513222B (en) * | 2009-02-18 | 2012-05-23 | 麦仑（厦门）生物科技有限公司 | Feeding acidifier prepared by emulsifying technology and preparing method thereof |
| CN102805266B (en) * | 2012-08-21 | 2013-09-25 | 山东新希望六和集团有限公司 | Feed for improving digestive and immunologic ability of chicken |
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