CN103861014B

CN103861014B - A kind of Chinese medicine oral liquid for the treatment of chronic gastritis

Info

Publication number: CN103861014B
Application number: CN201410124714.3A
Authority: CN
Inventors: 袁志贤
Original assignee: 袁志贤
Current assignee: Fujian tongyitangguo Pharmaceutical Development Co., Ltd
Priority date: 2014-03-31
Filing date: 2014-03-31
Publication date: 2016-03-16
Anticipated expiration: 2034-03-31
Also published as: WO2015149394A1; CN103861014A

Abstract

The invention discloses a kind of Chinese medicine oral liquid for the treatment of chronic gastritis, invention formulation is by Herba Pogostemonis, six is bent, Semen Lablab Album, Fructus Forsythiae, Poria, Semen Raphani, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, Radix Scutellariae, Herba Cistanches, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae are through pulverizing, decoct, the compositions liquid formulation that the operation such as ethanol extraction and mixing is prepared into, the present invention treats chronic gastritis successful, for glutted after meal, pantothenic acid, irregularities is suffered from abdominal pain, epigastric discomfort, pain, dyspepsia, vomiting, singultus, feel sick etc. symptom have obvious effect, and manufacture method is simple, effect stability, side effect is little.

Description

A kind of Chinese medicine oral liquid for the treatment of chronic gastritis

Technical field

The present invention relates to a kind of Chinese medicine oral liquid for the treatment of chronic gastritis, be specifically related to Chinese medicine oral liquid of this treatment chronic gastritis and preparation method thereof.

Background technology

Chronic gastritis, refers to the chronic inflammatory disease of the gastric mucosa caused by the different causes of disease, after its essence is that gastric epithelial suffers repeatedly to damage, causes mucosa to be reconstructed, finally causes the atrophy of irreversible intrinsic gastric gland body, even disappear.Chronic gastritis often reduces with atrophy (mucosa loss of function) to a certain degree and gastrin secretion, clinical symptoms main manifestations is Upper abdominal pain or discomfort, glutted, belch, feel sick, the symptom such as dyspepsia.The cause of disease of modern medicine to chronic gastritis is illustrated not yet completely, think may with improper diet, malnutrition, organize the factor such as congestion and anoxia relevant.At present, patient takes Western medicine to treat usually, but Western medicine is cured the symptoms, not the disease, can only temporary relief of symptoms, can not eradicate old complaint, and while treatment gastritis, also often injures the organs such as Liver and kidney, and curative effect is unstable, easily recurs.

Summary of the invention

Namely object of the present invention is for above-mentioned deficiency, on the basis of secret prescription handed down in the family from generation to generation, in conjunction with modern Chinese and western medicine technology, a kind of Chinese medicine oral liquid for the treatment of chronic gastritis is provided, is to provide this Chinese medicine oral liquid and preparation method thereof specifically, treating gastritis successful of the present invention, and it is nontoxic, have no side effect, effect stability, reparation technology is simple and easy to do.

Technical scheme of the present invention is as described below:

Invention formulation is the composite preparation be prepared into by Herba Pogostemonis, six songs, Semen Lablab Album, Fructus Forsythiae, Poria, Semen Raphani, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, Radix Scutellariae, Herba Cistanches, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae, and wherein the quality proportioning of each component is:

Herba Pogostemonis 12-20g six bent 10-22g Semen Lablab Album 8-18g

Fructus Forsythiae 10-18g Poria 8-15g Semen Raphani 10-20g

Radix Bupleuri 8-16g Caulis Bambusae In Taenia 12-20g Cortex Cinnamomi 8-16g

Fructus Amomi 10-18g Radix Aucklandiae 10-18g Fructus Crataegi (parched to brown) 10-18g

Fructus Hordei Germinatus (parched) 8-15g Rhizoma Coptidis 6-15g Semen Coicis 8-15g

Radix Scutellariae 10-18g Herba Cistanches 8-16g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15g

Semen setariae 10-20g.

In order to obtain better effect, the present invention can raw material mass mixture ratio be preferably:

Herba Pogostemonis 12-18g six bent 10-18g Semen Lablab Album 8-12g

Fructus Forsythiae 12-18g Poria 8-12g Semen Raphani 10-15g

Radix Bupleuri 8-12g Caulis Bambusae In Taenia 12-16g Cortex Cinnamomi 8-12g

Fructus Amomi 10-15g Radix Aucklandiae 10-14g Fructus Crataegi (parched to brown) 10-15g

Fructus Hordei Germinatus (parched) 8-12g Rhizoma Coptidis 6-10g Semen Coicis 8-12g

Radix Scutellariae 10-15g Herba Cistanches 8-12g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-12g

Semen setariae 12-18g.

Certainly, in order to obtain effect good further, the present invention can raw material mass mixture ratio be preferably also:

Herba Pogostemonis 15g six bent 12g Semen Lablab Album 9g

Fructus Forsythiae 15g Poria 10g Semen Raphani 12g

Radix Bupleuri 12g Caulis Bambusae In Taenia 10g Cortex Cinnamomi 8g

Fructus Amomi 12g Radix Aucklandiae 14g Fructus Crataegi (parched to brown) 12g

Fructus Hordei Germinatus (parched) 8g Rhizoma Coptidis 8g Semen Coicis 12g

Radix Scutellariae 10g Herba Cistanches 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g

Semen setariae 15g.

The preparation method of above-mentioned treatment chronic gastritis Chinese medicine oral liquid, comprises the steps:

1), by six songs put into pannikin and carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care 2-3 minute, then pulverize through pulverizer and cross 80 mesh sieves, for subsequent use;

2), by Herba Pogostemonis, Semen Lablab Album, Fructus Forsythiae, Poria, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Semen setariae, Radix Scutellariae, Herba Cistanches prepare in proportion, be ground into powder through pulverizer and cross 90 mesh sieves, naturally drying, for subsequent use;

3), by step 1) and 2) in each component powders mix, add pure water and decoct twice, first time adds 10 times of pure water and decocts 1 hour, and it is for subsequent use to extract filtrate; Second time adds 6 times of pure water and decocts half an hour, then collecting decoction filtering, for subsequent use;

4) Semen Raphani, by remaining, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, the Pseudobulbus Bletillae (Rhizoma Bletillae) prepare in proportion, are ground into powder and cross 80 mesh sieves, naturally dry through pulverizer, for subsequent use;

5), by component powders each in step 4) mix, add the ethanol of 4 ~ 6 times 70% ~ 80%, reflux 3 ~ 5 hours, extract and filter acquisition filtrate; Then in remaining medicinal residues, again add the ethanol of 2 ~ 4 times 65% ~ 75%, reflux 2 ~ 3 hours, extract and filter acquisition filtrate; The filtrate of twice acquisition is combined, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

6), by above-mentioned steps 5) in the dry cream that obtains carry out micronizing powdered and cross 200 wood sieves, then powder is added 3) collecting decoction in step, mixing shakes up and can obtain.

The above-mentioned Chinese medicine composition pharmaceutical solutions produced may be used for oral, if can the morning, noon and afternoon respectively drink once and long-term drink in right amount, and better effects if.

Theoretical foundation of the present invention is:

Herba Pogostemonis, slightly warm in nature, acrid-sweet flavor, there is removing dampness by means of aromatics, deliver expelling summer-heat, inducing diaphoresis to expel pathogens, dampness removing except wind, relieve heat and thirst, stomach function regulating preventing or arresting vomiting, fast gas and in, the effect such as stomach invigorating damp eliminating.Be generally used for the diseases such as treatment is had a headache and fever, anemofrigid cold, abdominal distention uncomfortable in chest, cold syndrome of the stomach pain, vomiting, dysentery, halitosis.

Burnt six is bent, sweet in the mouth, pungent, warm in nature, can help digestion, stomach invigorating, for dyspepsia, dyspeptic abdominal distention, diarrhoea, this product is the processed goods through fermentation after adopting Semen Armeniacae Amarum mud, Semen Phaseoli, Herba polygoni hydropiperis, Herba Artemisiae Annuae, flour, Herba Xanthii grass medicamental pulverata to mix, play QI and blood regulating in the present invention weak, disorder of stomach-QI, can not diet, and food does not often disappear, extremity Costumes is weak, and hundred diseases hand over the effect of attacking.

The pharmacological action of Semen Lablab Album in invention formulation mainly antibacterial, antiviral, experiment shows: the dull and stereotyped paper disk method of 100% Semen Lablab Album decoct, to dysentery bacterium and have inhibitory action; Detoxication is had to vomiting, acute gastroenteritis etc. that alimentary toxicosis causes.Semen Lablab Album water extract has inhibitory action to mice ColumbiaSK virus.

Fructus Forsythiae, bitter in the mouth, cold nature is Oleaceae forsythia, and Fructus Forsythiae first leaf in early spring is bloomed, and the flowers are in blossom, and fragrance is light gorgeous, and full branch is golden yellow, gorgeous lovely, and be excellent sight flowering shrub in early spring, fruit can be used as medicine.Fructus Forsythiae is mainly containing compounds such as phenethyl alcohol glycosides, lignan and glycoside, pentacyclic triterpene Lou, volatile oils.Pharmacological research thinks that it has antibacterial, antiinflammatory, antipyretic, town is told, diuresis heart tonifying, anti-liver damage, analgesia, suppress the effects such as phosphodiesterase, antiviral, blood pressure lowering, suppression elastin laminin enzyme activity, antiendotoxin.Except fruit medicine, tool heat-clearing and toxic substances removing, disappear outside the effect of knot evacuation of pus, its leaf medicinal, better to effect such as treatment hypertension, dysentery, throat pain etc.The Fructus Forsythiae pharmacological action such as have antibacterial, heart tonifying, diuresis, town to tell is the Chinese medicine of heat-clearing and toxic substances removing, cure mainly calentura from the beginning of, anemopyretic cold, heating, vexed, symptom, its bacteriostasis and the Flos Lonicerae broadly similar such as laryngopharynx swelling and pain, acute nephritis, carbuncle sore tumefacting virus.

Poria, the main component in Poria is pachyman, and content is very high.Inhibitory action is had to various bacteria; Can gastric acid be fallen, have preventive effect to digestive tract ulcer; Significant protective effect is had to hepatic injury; There is antineoplastic action; Many-sided immunologic function can be regulated; Leukopenia caused by chemotherapy can be made to accelerate; And have calm effect.

Semen Raphani, property is put down, acrid in the mouth, sweet.Return lung, spleen, stomach warp, cure mainly the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm.Cure mainly stagnation of QI due to dyspepsia, distension and fullness in the abdomen, belch, heavy after dysentery, cough with copious phlegm, dyspnea with rapid and short breath fullness in the chest, can help digestion de-swelling, and effect is remarkable, has the title of " rush wall fall wall ".Clinical habit is used for the treatment of real (eat, wet, stagnate) card.But these product are not only the de-swellings that helps digestion, and to deficiency syndrome with it, obtain effect also good, because of its property peace, its abnormal smells from the patient is not high again, and what without the fraud of victory partially, can not be limited to " rush wall fall wall " says there is the suspicion of dispelling the stagnated QI (being having a surplus of flat gas actually), and gives it up.

Radix Bupleuri, bitter in the mouth, pungent, cold nature; Return liver, gallbladder meridian; Micro-perfume rises loose; There is clearing away heat and expelling pathogen in the exterior, treating SHAO YANG disease by mediation, dispersing the stagnated live-QI to relieve the stagnation of QI, effect of ascending up spleen-Qi and Yang, cure mainly fever caused by exogenous pathogens, alternate attack of chill and fever, malaria, jaundice, distending pain in the chest and hypochondrium, headache conjunctival congestion, deaf bitter taste, menoxenia, visceroptosis, the proctoptosis prolapse of the uterus, recklessly can dispersing the stagnated live-QI to relieve the stagnation of QI, and joining resistance and supplementing qi medicine can ascending up spleen-Qi and Yang, for uterine prolapse, proctoptosis, so without promoting the production of body fluid the merit of quenching one's thirst; Radix Puerariae has promoting the production of body fluid to quench thirst effect, and energy hair growth promoting is positive clearly, for watery diarrhea, so without dispersing the stagnated live-QI to relieve the stagnation of QI function.

Caulis Bambusae In Taenia, property is sweet, is slightly cold, and enters lung, stomach, gallbladder meridian, cures mainly removing heat-phlegm, relieve restlessness and prevent vomiting.For phlegm-heat cough, expectorant held under the arm by gallbladder fire, and dysphoria with smothery sensation is vomitted, and eye is lost in palpitation with fear, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement.This product is good at clearing away phlegm preventing or arresting vomiting, clearing heat and relieving fidgetness, cards such as being applicable to phlegm-heat cough, gastric heat vomits the sound of vomiting, singultus is irritated, hold concurrently can removing heat from blood antiabortive, for frequent fetal movement, be the good medicine controlling gastric heat insufficiency of stomach vomiting simply.

Cortex Cinnamomi, can complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion is collapsed, and stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea lump in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower, and Cortex Cinnamomi powder warm water takes, and can treat flatulence, cold syndrome of the stomach pain; Cortex Cinnamomi powder is added in dish and cooks, can contribute to controlling blood glucose and cholesterol.

Fructus Amomi, acrid in the mouth, warm in nature, return spleen channel, stomach warp, kidney channel.Can removing dampness whet the appetite, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive, be usually used in turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, and vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.Fructus Amomi kind energy warming middle-JIAO warming the stomach is to reach the merit of preventing or arresting vomiting antidiarrheal, but it focuses on warming the spleen.

The Radix Aucklandiae, acrid in the mouth; Bitter; Warm in nature, return spleen; Large intestine, tri-jiao channel.Can circulation of qi promoting, pain relieving, spleen invigorating, helps digestion, and cures mainly promoting the circulation of QI to relieve pain; Intestinal stasis relieving in tune.Main born of the same parents coerce distension foot; Abdominal distention; Tell and have loose bowels; Heavy after dysentery.For weighing after breast gastral cavity distending pain, dysentery, food stagnation does not disappear, anorexia; Middle gas is not economized; Sudden deafness; Snake bite and insect sting; Toothache.As the distension and fullness in the abdomen of stagnation of QI in spleen and stomach or pain in the traditional Chinese medical science, belch, nausea and vomiting medicine.

Fructus Crataegi (parched to brown) gets clean Fructus Crataegi, fries to surface coke brown, inner yellowish-brown according to frying method.This product shape as Fructus Crataegi slice, surface coke brown, inner yellowish-brown.There is burnt odor gas.Sour in the mouth, sweet, tepor, return spleen, stomach, Liver Channel.Can promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery is suffered from abdominal pain, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.

Fructus Hordei Germinatus (parched), sweet in the mouth, property is put down.Return spleen, stomach warp, demonstrate,prove for rice and flour Rhizoma Dioscoreae dyspepsia.This product can promote the digestion of starchiness food.Can use with Fructus Crataegi (parched to brown), six bent being equal to.Children's's Ruo Zhi breast food is stagnated, alone this product decoction or grind clothes into powder effectively.If control insufficiency of the spleen lack of appetite, glutted after food, can with Semen Lablab Album, Pericarpium Citri Reticulatae is equivalent to be used.

Rhizoma Coptidis can heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.This product is held concurrently can dispersing the stagnated live-QI to relieve the stagnation of QI, for the hypochondriac pain, abdominal pain etc. of irritability stasis or incoordination between the liver and stomach, and can with other Calming liver to disperse Qi decoctions with use.

Semen Coicis, cool in nature, sweet in the mouth, light, be the kernel of grass Semen Coicis.There is spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.For effect of edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.Function cures mainly: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.

Radix Scutellariae, another name Radix Scutellariae, tsuchikane tea root.For labiate, be used as medicine with root.Have heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.

Herba Cistanches is sweet in the mouth, salty, warm in nature.Return kidney, large intestine channel, can kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation.

The Pseudobulbus Bletillae (Rhizoma Bletillae), cold in nature, bitter in the mouth, sweet, puckery, nontoxic; Return lung, stomach, Liver Channel.There is astringing to arrest bleeding, the function of detumescence and promoting granulation.Cure mainly pulmonary tuberculosis slightly blood, spit blood, epistaxis, has blood in stool, traumatic hemorrhage, carbuncle pyogenic infections from tumour or sore, scrofula, anal fistula, burn and scald, rhagadia manus et pedis, the diseases such as anal fissure.With other drug matchings of the present invention, treatment enteritis successful.

Semen setariae is that foxtail millet (Setariaitalica) shells the grain made, because it is little, and diameter 1 millimeter, therefore named.Originate in the north of China Huanghe valley, the staple food crop of ancient Chinese, so Xia dynasty and Shang dynasty belong to " foxtail millet culture ".Foxtail millet growth is drought-enduring, various in style, is commonly called as " foxtail millet has the five colours ", Semen setariae sweet in the mouth cool in nature, can disappear by preventing or arresting vomiting, supports the intestines and stomach, relieving constipation, stopping leak, blood yiqi, spleen invigorating, hypoglycemic and thirst-relieving, yin nourishing tonify deficiency, has well conditioning and tonic effect to gastrointestinal tract: cure mainly dyspepsia: vitamin B group can be secreted by facilitating digestion liquid, maintain and promote intestinal peristalsis promoting, being conducive to defecation.And effect of the raw skin ulcer of bicker, and nourishing the stomach: in and gastric acid, alleviate stomachache.Semen setariae has the effect preventing general stomach, vomiting.

From China's Traditional Chinese Medicine angle, the etiology and pathogenesis of chronic gastritis, there is eating and drinking without temperance, kill damaging the spleen and stomach state, or invade in exopathogen, undermine taste, or suffering is disgruntled, the liver failing to maintain the normal flow of QI, perverse and unreasonable manner violates stomach, and innate deficiency, the situations such as weakness of the spleen and stomach, its sick table is at " stomach ", but with " spleen ", " liver ", " kidney " is in close relations, pathogenic characteristic is deficiency complicated with excess, therefore the compositions of the above-mentioned drug matching of the present invention and preparation method acquisition is passed through, dialectical method is adopted effectively to reach effect of regulating stomach and the vital organs of the human body, have no side effect, effect stability, the curative effect of getting twice the result with half the effort is reached compared with Western medicine.

clinical experiment 1:

1), observing time: when technical solution of the present invention does not disclose, select 6 months of in March, 2013 in August, 2013.

2), the object of observation: select 10 routine chronic gastritis cases in Dongguan City, Guangdong Province Gastroenterology dept. of institute of traditional Chinese medicine: man 6 example, female 4 example; Age: 40-55 years old 5 example, 60-75 years old 5 example; Occupation: common working clan 5 example, retired person 5 example.Disease: glutted after meal, pantothenic acid, the symptoms such as irregularities stomachache.

3), using method: taken half an hour after the meal by invention formulation oral liquid, every day 3 times, each 200ml, 2 months be 1 course for the treatment of, 3 courses for the treatment of are as observation of curative effect.

4), observing effect:

After taking 3 courses for the treatment of continuously, glutted after meal, pantothenic acid, 6 examples that the symptoms such as irregularities stomachache substantially no longer occur, have feeling of repletion after meal a little, slight pantothenic acid, irregularities such as slightly to be suffered from abdominal pain at 2 examples that symptom substantially no longer occurs, glutted after meal, pantothenic acid, irregularities stomachache improves unconspicuous 2 examples, total effective rate 80%.

clinical experiment 2 :

1), observing time: when technical solution of the present invention does not disclose, select in April, 2013 by 6 months of in JIUYUE, 2013.

2), the object of observation: select 20 routine cases in Gastroenterology dept. of Shahe hospital of Shenzhen City, Guangdong Province Nanshan District: man 12 example, female 8 example; Age: 32-55 years old 10 example, 56-75 years old 10 example; Occupation: once assumed the leadership post civil servant 10 example, common teachers 10 example.Disease: epigastric discomfort, pain, dyspepsia, vomiting, singultus is felt sick.

4), observing effect:

After taking 3 courses for the treatment of continuously, the abdominal pain that patient is original, dyspepsia disappears, vomiting, 12 examples that singultus and feeling sick etc. substantially no longer occurs, slight abdominal pain and dyspepsia, slightly vomit once in a while, singultus and 3 examples of feeling sick, abdominal pain, dyspepsia disappears, vomiting, singultus and unconspicuous 5 examples of improvement of feeling sick, total effective rate 75%.

clinical experiment 3 :

1), observing time: when technical solution of the present invention does not disclose, select in July, 2013 by 6 months of in December, 2013.

2), the object of observation: select 30 routine cases in Gastroenterology dept. of Shenzhen City, Guangdong Province BeiJing University ShenZhen Hospital: man 12 example, female 18 example; Age: 35-55 years old 16 example, 60-75 years old 14 example; Occupation: common private enterprise master 14 example, common retired professor 16 example.Disease: glutted after meal, pantothenic acid, irregularities is suffered from abdominal pain, epigastric discomfort, pain, dyspepsia, vomiting, and singultus is felt sick.

4), observing effect:

After taking 3 courses for the treatment of continuously, the abdominal pain that patient is original, dyspepsia disappears, vomiting, 18 examples that singultus and feeling sick etc. substantially no longer occurs, slight abdominal pain and dyspepsia, slightly vomit once in a while, singultus and 6 examples of feeling sick, abdominal pain, dyspepsia, vomiting, singultus and unconspicuous 6 examples of improvement of feeling sick, total effective rate 80%.

In conjunction with above clinical data and theoretical foundation of the present invention, visible beneficial effect of the present invention is, the preparation that the present invention makes, and has good result for treatment chronic gastritis, and nontoxic, and have no side effect, effect stability, reparation technology is simple and easy to do.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is explained detailedly:

embodiment 1:

Herba Pogostemonis 12g six bent 10g Semen Lablab Album 10g

Fructus Forsythiae 12g Poria 12g Semen Raphani 15g

Radix Bupleuri 10g Caulis Bambusae In Taenia 12g Cortex Cinnamomi 8g

Fructus Amomi 15g Radix Aucklandiae 15g Fructus Crataegi (parched to brown) 13g

Fructus Hordei Germinatus (parched) 12g Rhizoma Coptidis 8g Semen Coicis 10g

Radix Scutellariae 12g Herba Cistanches 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g

Semen setariae 16g.

3), by step 1) and 2) in each component powders mix, add pure water and decoct twice, first time adds the little fire of 8 times of pure water and decocts 1 hour, and second time adds 4 times of little fire of pure water and decocts half an hour, then collecting decoction filtering, for subsequent use;

6), by above-mentioned steps 5) in obtain dry cream carry out micronizing powdered and cross 200 mesh sieves, then powder is added the collecting decoction in step 3), mixing shake up and can obtain.

The above-mentioned Chinese medicine composition pharmaceutical solutions produced may be used for oral, if can respectively drink the morning, noon and afternoon once and long-term drink, and better effects if.

embodiment 2:

The present invention can raw materials quality be preferably also (gram):

Herba Pogostemonis 12g six bent 10g Semen Lablab Album 10g

Fructus Forsythiae 12g Poria 12g Semen Raphani 15g

Radix Bupleuri 10g Caulis Bambusae In Taenia 12g Cortex Cinnamomi 8g

Fructus Amomi 15g Radix Aucklandiae 10g Fructus Crataegi (parched to brown) 13g

Fructus Hordei Germinatus (parched) 12g Rhizoma Coptidis 8g Semen Coicis 10g

Semen setariae 16g.

Preparation method is as embodiment 1.

embodiment 3:

The present invention can raw materials quality be preferably also (gram):

Herba Pogostemonis 15g six bent 12g Semen Lablab Album 9g

Fructus Forsythiae 15g Poria 10g Semen Raphani 12g

Radix Bupleuri 12g Caulis Bambusae In Taenia 10g Cortex Cinnamomi 8g

Fructus Amomi 12g Radix Aucklandiae 14g Fructus Crataegi (parched to brown) 12g

Fructus Hordei Germinatus (parched) 8g Rhizoma Coptidis 8g Semen Coicis 12g

Semen setariae 15g.

Preparation method is as embodiment 1.

embodiment 4:

The present invention can raw materials quality be preferably also (gram):

Herba Pogostemonis 18g six bent 15g Semen Lablab Album 12g

Fructus Forsythiae 16g Poria 12g Semen Raphani 15g

Radix Bupleuri 13g Caulis Bambusae In Taenia 15g Cortex Cinnamomi 12g

Fructus Amomi 16g Radix Aucklandiae 14g Fructus Crataegi (parched to brown) 16g

Fructus Hordei Germinatus (parched) 10g Rhizoma Coptidis 12g Semen Coicis 15g

Radix Scutellariae 16g Herba Cistanches 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 12g

Semen setariae 18g.

Preparation method is as embodiment 1.

embodiment 5 :

The present invention can raw materials quality be preferably also (gram):

Herba Pogostemonis 16g six bent 18g Semen Lablab Album 15g

Fructus Forsythiae 14g Poria 15g Semen Raphani 18g

Radix Bupleuri 15g Caulis Bambusae In Taenia 18g Cortex Cinnamomi 14g

Fructus Amomi 18g Radix Aucklandiae 16g Fructus Crataegi (parched to brown) 14g

Fructus Hordei Germinatus (parched) 12g Rhizoma Coptidis 13g Semen Coicis 13g

Radix Scutellariae 18g Herba Cistanches 15g Pseudobulbus Bletillae (Rhizoma Bletillae) 15g

Semen setariae 18g.

Preparation method is as embodiment 1.

embodiment 6 :

The present invention can raw materials quality be preferably also (gram):

Herba Pogostemonis 15g six bent 18g Semen Lablab Album 15g

Fructus Forsythiae 16g Poria 15g Semen Raphani 20g

Radix Bupleuri 12g Caulis Bambusae In Taenia 20g Cortex Cinnamomi 16g

Fructus Amomi 16g Radix Aucklandiae 18g Fructus Crataegi (parched to brown) 15g

Fructus Hordei Germinatus (parched) 15g Rhizoma Coptidis 15g Semen Coicis 12g

Radix Scutellariae 16g Herba Cistanches 16g Pseudobulbus Bletillae (Rhizoma Bletillae) 13g

Semen setariae 20g.

Preparation method is as embodiment 1.

Above-described embodiment is only the several of the numerous embodiment of the present invention, and as strengthened in the ratio in technical scheme by each formula or reducing dose, obtained this treatment chronic gastritis preparation curative effect is also unaffected, also will drop within the scope of the present invention.

Claims

1. treat the Chinese medicine oral liquid of chronic gastritis for one kind, it is characterized in that, this Chinese medicine oral liquid is the composite preparation be prepared into by Herba Pogostemonis, six songs, Semen Lablab Album, Fructus Forsythiae, Poria, Semen Raphani, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, Radix Scutellariae, Herba Cistanches, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae, and wherein the quality proportioning of each component is:

2. the Chinese medicine oral liquid for the treatment of chronic gastritis according to claim 1, is further characterized in that, wherein the quality proportioning of each component is:

3. treat a Chinese medicine oral liquid for chronic gastritis, it is characterized in that, wherein the quality proportioning of each component is:

4., according to a kind of preparation method for the treatment of the Chinese medicine oral liquid of chronic gastritis of claim 1-3 described in any one, it is characterized in that, it comprises the steps:

3), by step 1) and 2) in each component powders mix, add pure water and decoct twice, first time adds the little fire of 10 times of pure water and decocts 1 hour, extract filtrate for subsequent use, second time adds the little fire of 6 times of pure water and decocts half an hour, then collecting decoction filtering, for subsequent use;

5), by step 4) in each component powders mix, add the ethanol of 4 ~ 6 times 70% ~ 80%, reflux 3 ~ 5 hours, extract filter obtain filtrate; Then in remaining medicinal residues, again add the ethanol of 2 ~ 4 times 65% ~ 75%, reflux 2 ~ 3 hours, extract and filter acquisition filtrate; The filtrate of twice acquisition is combined, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

6), by above-mentioned steps 5) in obtain dry cream carry out micronizing powdered and cross 200 mesh sieves, then powder is added step 3) in collecting decoction, mixing shake up and can obtain.