CN103845583B - A kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis - Google Patents

A kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis Download PDF

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CN103845583B
CN103845583B CN201410103800.6A CN201410103800A CN103845583B CN 103845583 B CN103845583 B CN 103845583B CN 201410103800 A CN201410103800 A CN 201410103800A CN 103845583 B CN103845583 B CN 103845583B
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CN103845583A (en
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张继莲
于燕霞
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Han Fang medical science and Technology (Guangzhou) Co., Ltd.
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张继莲
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Abstract

The invention discloses a kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis, belong to the field of Chinese medicines, the raw material of Chinese medicine preparation effective ingredient of the present invention consists of: Folium Malloti Apeltae, Herba stellariae mediae, Herba Xanthii, Herba senecionis nemorensis, Spora Lygodii, Radix Bupleuri, Fructus Schisandrae Chinensis, Herba Apii graveolentis, river cypress, Rhizoma Paridis, Herba Dichodrae, Maifanitum, Rhizoma Curculiginis, ligustrum sinense, Radix Achyranthis Bidentatae and Bulbus Allii Macrostemonis; Chinese medicine preparation of the present invention selects Chinese crude drug to be raw material, compatibility meets Chinese medicine and modern medicine and pharmacology research theory has, tool dispersing the stagnated live-QI to relieve the stagnation of QI, benefiting QI and nourishing blood, keep fit effect of liver, improve body autoimmunity, suppress and eliminate hepatitis virus, recovering liver function, short treating period instant effect, there is the curative effect for the treatment of both the principal and secondary aspects of a disease, the clinical treatment of chronic hepatitis can be widely used in.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis.
Background technology
Chronic hepatitis refers to and is caused by different pathogeny, and the course of disease is at least continued above hepatic necrosis and the inflammation of more than 6 months, and as infected hepatitis virus (hepatitis B virus, hepatitis C virus), long-term alcohol, takes hepatotoxic medication etc.Corresponding symptom, sign regulating liver-QI biochemical analysis can be had clinically abnormal, also can without obvious clinical symptoms, only there are necrosis and the inflammation of hepatic tissue, necrosis of liver tissue in various degree and inflammatory reaction, there is hepatic fibrosis subsequently, the course of disease is undulatory property or lasting Progressive symmetric erythrokeratodermia, if do not carried out suitable treatment, finally can develop into liver cirrhosis.
The early symptom of classic chronic hepatitis is slight and lack specificity, intermittent in undulatory property, even for many years without any symptom.Modal is exactly easy tired and stomach discomfort, and be easily left in the basket, being also easily mistaken as is gastropathy; Often see invisible liver cirrhosis patient clinically, before there is liver cirrhosis, do not feel significant discomfort, also do not carry out conventional health check-up, progressively developing into liver cirrhosis unconsciously; Occasionally there is patient to occur feeling sick, abdominal distention, jaundice, urine color depth, but the order of severity of chronic hepatitis can not be judged according to symptom.
Severely chronic hepatitis and chronic severe hepatitis, when Urinary color Progressive symmetric erythrokeratodermia is deepened, skin yellow sclera Progressive symmetric erythrokeratodermia is deepened, when weak appetite declines more and more obviously, sb.'s illness took a turn for the worse in prompting, especially needs the generation of vigilant chronic severe hepatitis, chronic severe hepatitis is the performance of liver failure, can show as highly weak, height abdominal distention, height jaundice and height inappetence, hypoproteinemia can be there is, ascites hydrothorax, abdominal cavity infection, coagulation function declines, upper gastrointestinal hemorrhage, hepatic encephalopathies etc., mortality rate is higher clinically, needs actively to give treatment to.
Chronic hepatitis complication is comparatively general, as chronic cholecystitis, and hepatogenous diabetes, HBV-associated nephropathy etc.On the basis of chronic hepatitis, when having that inducement is as overworked in patient, heavy drinking or other hepatitis viruss of superinfection time, state of an illness sharp deterioration can be there is, develop into chronic severe hepatitis.
, there is the deficiency of two aspects in the field of Chinese medicines of current treatment chronic hepatitis: one is that effect is obvious not, two be take effect slower.So that large quantities of chronic hepatitis patient is because can not get the treatment of active drug, liver disease development, clinical symptoms can not get alleviating, patient is long-term, and seriously weak, dull pain in liver, liver function decline, hepatic fibrosis is serious, in the treatment of this type of medicine, effect is obvious not, take effect slower problem, and the Chinese medicine therefore researching and developing a kind of safe and effective treatment chronic hepatitis becomes the emphasis of modern medicine study.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis; Chinese medicine preparation of the present invention selects Chinese crude drug to be raw material, compatibility meets Chinese medicine and modern medicine and pharmacology research theory has, tool dispersing the stagnated live-QI to relieve the stagnation of QI, benefiting QI and nourishing blood, keep fit effect of liver, improve body autoimmunity, suppress and eliminate hepatitis virus, recovering liver function, short treating period instant effect, there is the curative effect for the treatment of both the principal and secondary aspects of a disease, the clinical treatment of chronic hepatitis can be widely used in.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for chronic hepatitis, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of chronic hepatitis, comprise following processing step:
(1) Folium Malloti Apeltae, Herba Xanthii, Herba senecionis nemorensis, Spora Lygodii, Fructus Schisandrae Chinensis, Rhizoma Paridis, Herba Dichodrae, ligustrum sinense and Radix Achyranthis Bidentatae are cleaned, put into container, add the distilled water of 8 ~ 12 times amount, soak after 4 ~ 5 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 50 DEG C is the thick paste of 1.10 ~ 1.14, for subsequent use;
(2) Herba stellariae mediae, Herba Apii graveolentis and Bulbus Allii Macrostemonis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) by Radix Bupleuri decontamination, clean, section, dries, is placed in container, mixes thoroughly with vinegar, puts in pot to fry with slow fire to exhaust and micro-dry to vinegar, takes out, dries, be placed in mortar, grind into powder, cross 180 order fine powders for subsequent use;
(4) river cypress, Maifanitum and Rhizoma Curculiginis decontamination are dried, be placed in mortar and grind into powder, cross 160 order fine powders, for subsequent use;
(5) made for above-mentioned steps (1) ~ (4) thick paste, juice and fine powder are mixed, make capsule, both the Chinese medicine preparation for the treatment of chronic hepatitis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Folium Malloti Apeltae: mildly bitter flavor, puckery, property is put down.Easing the affected liver is invigorated blood circulation, invigorating the spleen for eliminating dampness, solid de-, the anti-inflammation hemostasia of convergence.For chronic hepatitis, hepatosplenomegaly, uterine prolapse, proctoptosis, leucorrhea, edema during pregnancy; Otitis media is controlled in external, furuncle and phyma, traumatic injury, traumatic hemorrhage." Nanning City's medicine will " carries: " heat clearing away, diuretic, wind-damp dispelling, pain relieving.Control stranguria with turbid discharge, hemorrhoid, traumatic injury, snakebite.Antipruritic, detumescence.”
Herba stellariae mediae: mildly bitter flavor, sweet, sour, cool in nature; Return liver, large intestine channel.Heat-clearing and toxic substances removing, blood-activating analgetic, lactogenic.For enteritis, dysentery, hepatitis, appendicitis, postnatal blood stasis is suffered from abdominal pain, uterine contraction pain, toothache, early whitening of hair, agalactia, mastitis, traumatic injury, sore swollen toxin." illustrated handbook planted by middle traditional Chinese medicines " carries: " leave rubs juice, and skin ulcer wound is controlled in external; Stem and leaf is mixed salt and is stung it, can control toothache; Vinegar and, or charred medicinal herb with its property retained Oleum Sesami dresses skin ulcer and toxic swelling.”
Herba Xanthii: bitter in the mouth, pungent, cold nature, mild toxicity; Return lung, spleen, Liver Channel.Wind and heat eliminating, removing dampness and detoxicating.Cure mainly flu, wind syndrome of head, dizzy, nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture numbness, wind leprosy, furuncle, scabies, skin pruritus, hemorrhoid, dysentery etc." Guangdong Chinese medicine " carries: " control red cloud blood tinea, phlegm-fire core, flu, nasal sinusitis.”
Herba senecionis nemorensis: bitter in the mouth is pungent, cold in nature; Enter liver, spleen channel.Heat-clearing and toxic substances removing.Cure mainly dysentery, enteritis, hepatitis, conjunctivitis, otitis media, carbuncle treats poison, swelling around the eyes, carbuncle furuncle furunculosis.
Spora Lygodii: sweet in the mouth, cold in nature; Return bladder, small intestine meridian.Eliminating damp-heat, treating stranguria pain relieving.Cure mainly urinary tract infection, lithangiuria, nebulousurine, leucorrhea, hepatitis, oedema due to nephritis, laryngopharynx swelling and pain, mumps, enteritis, dysentery, skin eczema, herpes zoster." Jiangxi medical herbs " carries, " heat-clearing and toxic substances removing, promoting urination to remove dampness.Treating the liver is scorching, renal edema, skin eczema, chickenpox, hematuria.Mumps, acute toothache, throat moth, diphtheria, herpes zoster, children's L infantile malnutrition ".
Radix Bupleuri: bitter in the mouth, pungent, cold nature; Return liver, gallbladder meridian.Depressed liver-energy dispersing and function of gallbladder promoting, dredge gas resolving depression, expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Cure mainly cold, fever, cold and heat deficient fever, children's's varioliform exanthema waste heat, emaciation and sallow complexion abdominal part expands, malaria, stagnation of QI due to depression of the liver, sternal rib pain, proctoptosis, and uterus comes off, menoxenia.Modern medicine study confirms, the heating of Radix Bupleuri decoct has obvious refrigeration function, all has inhibitory action to the inflammation caused by multiple proinflammatory agent, and can Promote immunity function.
Fructus Schisandrae Chinensis: sour in the mouth, sweet, warm in nature; Return lung, the heart, kidney channel.To astringe the lung nourishing kidney, receipts of promoting the production of body fluid antiperspirant, arresting seminal emission.Modern medicine study confirms, Fructus Schisandrae Chinensis can protect human five internal organs's heart, liver, spleen, lung, kidney, and the strong liver of energy QI invigorating, the detoxification processes promoting liver, the liver protecting are from murder by poisoning, and the liver organization of energy regeneration of damaged.The strong liver of energy QI invigorating, the efficiency of promoting cells exclude refuse, supply more oxygen, construction and utilization energy.
Herba Apii graveolentis: sweet in the mouth, pungent, cool in nature; Enter liver, gallbladder, pericardium channel.Suppressing the hyperactive liver stomach invigorating, liver heat removing profit blood, expelling wind and removing dampness.Cure mainly hypertension, dizziness and headache, flushing conjunctival congestion, stranguria with blood, carbuncle." book on Chinese herbal medicine pushes away old " carries: " treating the liver sun is dizzy.Flushing conjunctival congestion, top-heavy, walking such as to be swayed the disease." modern medicine study confirmation, Herba Apii graveolentis contains abundant vitamin A, vitamin B1, vitamin B2, vitamin C and Citrin, calcium, ferrum, and the content of mineral substances such as phosphorus are also many, also has the compositions such as protein, mannitol and dietary fiber in addition.
River cypress: bitter in the mouth, cold in nature; Enter kidney, urinary bladder channel.Heat clearing and damp drying, eliminating fire and detoxication.Cure mainly hematodiarrhoea, have loose bowels, quench one's thirst, jaundice , flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, also under leucorrhea, and hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.Carry according to " Japan hanako materia medica ": " feel at ease, except labor, to control hectic fever due to YIN-deficiency, liver of waking up, improving eyesight, many tear, xerostomia, heat in the heart, kill infantile malnutrition worm, control ascarid pained, scabies, processed with honey controls serious epistaxis, and hemorrhoidal hamorrhage rushes down blood, and rear point anxious heat swells and ache.”
Rhizoma Paridis: bitter in the mouth, cool in nature, mild toxicity; GUIXIN, liver, lung, stomach, large intestine channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, cool liver arresting convulsion.Cure mainly carbuncle sore tumefacting virus, pharyngeal swelling sore throat, acute mastitis, snake bite and insect sting, traumatic pain, liver-heat is twitched.Modern medicine study confirms, Rhizoma Paridis has good result to woman's galactostasis of managing property.
Herba Dichodrae: acrid in the mouth, property is put down.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.For hepatitis, cholecystitis, dysentery, oedema due to nephritis, urinary system infection, urinary system calculus, tonsillitis, traumatic injury.
Maifanitum: sweet in the mouth, warm in nature, nontoxic; Return liver, stomach, kidney channel.Detoxicating and resolving stagnation of pathogens, removing the necrotic tissue and promoting granulation, except cold damp eliminating, the liver benefiting stomach invigorating, blood circulation promoting and blood stasis dispelling, diuresis fossil.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.
Rhizoma Curculiginis: acrid in the mouth, hot in nature, poisonous; Return kidney,liver,spleen warp.Kidney-replenishing, bone and muscle strengthening, dispelling cold and dampness.For sexual impotence cold sperm, muscles and bones flaccidity is soft, the cold numbness of waist knee joint, yang deficiency cold diarrhea." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " control that married woman is red collapses hematochezia, attack carbuncle, evacuation of pus.”
Ligustrum sinense: bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, bacteriostasis and sterilization, reducing swelling and alleviating pain, putrefaction-removing granulation-promoting, for acute icteric infectious hepatitis, dysentery, cough due to lung-heat; Traumatic injury is controlled in external, traumatic infection, burn and scald, the surgical infection diseases such as sore swollen toxin.
Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is put down; Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, ignites descending, inducing diuresis for treating stranguria syndrome.Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis, lump in the abdomen, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain." detailed outline " carries: " control chronic malaria cold and heat, five types of stranguria hematuria, pains in the penis, dysentery, sore throat, aphtha, toothache, carbuncle malignant boil, traumatics fracture." modern medicine study confirmation, Radix Achyranthis Bidentatae has good protein assimilation and anti-inflammatory and analgesic effect.
Bulbus Allii Macrostemonis: acrid in the mouth, hardship, warm in nature; Return lung, the heart, stomach, large intestine channel.To regulate the flow of vital energy the chest stuffiness relieving, activating YANG and eliminating stagnation.Cure mainly the thorough back of the body of obstruction of qi in the chest and cardialgia, breast gastral cavity painful abdominal mass is vexed, cough with asthma abundant expectoration, epigastric pain, heavy after letting out dysentery, leucorrhea, furuncle carbuncle.Modern medicine study confirms, Bulbus Allii Macrostemonis water decoction has inhibitory action to dysentery bacterium, staphylococcus aureus, and 300% water decoction tube dilution method, 1:4 has inhibitory action to staphylococcus aureus, streptococcus pneumoniae, has inhibitory action during 1:16 to sarcina.
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention selects Chinese crude drug to be raw material, compatibility meets Chinese medicine and modern medicine and pharmacology research theory has, tool dispersing the stagnated live-QI to relieve the stagnation of QI, benefiting QI and nourishing blood, keep fit effect of liver, improve body autoimmunity, suppress and eliminate hepatitis virus, recovering liver function, short treating period instant effect, there is the curative effect for the treatment of both the principal and secondary aspects of a disease, the clinical treatment of chronic hepatitis can be widely used in.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Treat a preparation method for the Chinese medicine preparation of chronic hepatitis, comprise following processing step:
(1) Folium Malloti Apeltae, Herba Xanthii, Herba senecionis nemorensis, Spora Lygodii, Fructus Schisandrae Chinensis, Rhizoma Paridis, Herba Dichodrae, ligustrum sinense and Radix Achyranthis Bidentatae are cleaned, put into container, add the distilled water of 8 ~ 12 times amount, soak after 4 ~ 5 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 50 DEG C is the thick paste of 1.10 ~ 1.14, for subsequent use;
(2) Herba stellariae mediae, Herba Apii graveolentis and Bulbus Allii Macrostemonis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) by Radix Bupleuri decontamination, clean, section, dries, is placed in container, mixes thoroughly with vinegar, puts in pot to fry with slow fire to exhaust and micro-dry to vinegar, takes out, dries, be placed in mortar, grind into powder, cross 180 order fine powders for subsequent use;
(4) river cypress, Maifanitum and Rhizoma Curculiginis decontamination are dried, be placed in mortar and grind into powder, cross 160 order fine powders, for subsequent use;
(5) made for above-mentioned steps (1) ~ (4) thick paste, juice and fine powder are mixed, make capsule, both the Chinese medicine preparation for the treatment of chronic hepatitis of the present invention.
Usage and dosage: oral, every day 2 times, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, 3 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of chronic hepatitis, select the routine clinical observation of chronic hepatitis patient 400 of making a definite diagnosis.
Patient is divided into treatment group and matched group two groups at random, treatment group 200 example, wherein male 105 example, women 95 example, 30 ~ 62 years old age, 45.5 years old mean age, the shortest person of the course of disease 2 months, most elder 5 years, average 2.8 years; Matched group 200 example, wherein male 104 example, women 96 example, 31 ~ 63 years old age, 46.5 years old mean age, the shortest person of the course of disease 3 months, most elder 6 years, average 3.1 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, Chinese medicine preparation is selected:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 2 times, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, take 3 ~ 4 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice.
Matched group injection potassium magnesium aspartate and glucose injection, intravenous drip, a 10 ~ 20ml, adds in 5% glucose injection 500ml and slowly instils, every day 1 time, or follows the doctor's advice; Within 20 days, be 1 course for the treatment of, treat 2 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice.
3, efficacy determination:
(1) cure: patient clinical symptom all disappears, liver function recovery is normal, and health indices recovers normal on inspection.
(2) effective: patient clinical symptom major part disappears, and health indices raises all to some extent on inspection.
(3) effective: patient clinical symptom is slightly good, and health indices all increases on inspection.
(4) invalid: by treating rear clinical symptoms without significant change.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 80 examples, effective 72 examples, effective 45 examples, invalid 3 examples, cure rate 40%, total effective rate 98.5%.
40 examples are cured, effective 50 examples, effective 30 examples, invalid 80 examples, cure rate 20%, total effective rate 60% in matched group.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, what certain, man, 35 years old, people from Dalian.The long-term anorexia of patient, weak, complexion yellowish-brown simple and unadorned, color of the lip is dark violet, remove examination in hospital, it is early stage that laboratory test report is shown as chronic hepatitis, after taking 1 course for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom fades away, and after taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, cures, again chemically examine, laboratory test report display liver function recovery is normal.
2, Lee, female, 42 years old, people from Liaoyuan, Jilin.Patient suffers from acute jaundice chronic hepatitis, the mobility of thrombinogen is lower than 40%, serum bilirubin and alaninyl transferring enzyme high, take multi-medicament treatment all without positive effect, rear beginning takes medicine Chinese medicine preparation of the present invention, after taking 4 courses for the treatment of, the mobility of thrombinogen, serum bilirubin and alaninyl transferring enzyme all recover normal value, no longer recur after healing, follow up a case by regular visits to, do not recur again so far.
3, high certain, man, 51 years old, Yancheng, Jiangsu Province people.Patient's suffering from liver cirrhosis, xerosis cutis is coarse, and complexion is gloomy, and to have vomiting and diarrhoea, and be even unable to leave the bed, through multi-treatment all without onset, patient is close to despair.To our hospital afterwards, after taking 1 course for the treatment of of Chinese medicine preparation of the present invention, the state of an illness is obviously suppressed, and can do some daily housework, after taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, curing, recovers as ordinary person, following up a case by regular visits to after 1 year without recurring.

Claims (5)

1. treat a Chinese medicine preparation for chronic hepatitis, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Folium Malloti Apeltae 43 ~ 73 parts of Herba stellariae mediaes 33 ~ 63 portions of Herba Xanthiis 33 ~ 63 parts of Herba senecionis nemorensis 33 ~ 58 parts
Spora Lygodii 28 ~ 58 parts of Radix Bupleuri 28 ~ 53 parts of Fructus Schisandrae Chinensis 23 ~ 53 portions of Herba Apii graveolentis 23 ~ 48 parts
River cypress 23 ~ 48 parts of Rhizoma Paridis 18 ~ 48 parts of Herba Dichodraees 18 ~ 48 parts of Maifanitums 13 ~ 48 parts
Rhizoma Curculiginis 13 ~ 43 parts of ligustrum sinenses 11 ~ 43 parts of Radix Achyranthis Bidentataes 11 ~ 38 parts of Bulbus Allii Macrostemonis 9 ~ 33 parts.
2. a kind of Chinese medicine preparation for the treatment of chronic hepatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Folium Malloti Apeltae 48 ~ 68 parts of Herba stellariae mediaes 38 ~ 58 portions of Herba Xanthiis 38 ~ 58 parts of Herba senecionis nemorensis 37 ~ 54 parts
Spora Lygodii 33 ~ 53 parts of Radix Bupleuri 32 ~ 49 parts of Fructus Schisandrae Chinensis 28 ~ 48 portions of Herba Apii graveolentis 27 ~ 44 parts
River cypress 27 ~ 44 parts of Rhizoma Paridis 23 ~ 43 parts of Herba Dichodraees 23 ~ 43 parts of Maifanitums 19 ~ 42 parts
Rhizoma Curculiginis 18 ~ 38 parts of ligustrum sinenses 16 ~ 38 parts of Radix Achyranthis Bidentataes 15 ~ 34 parts of Bulbus Allii Macrostemonis 13 ~ 29 parts.
3. a kind of Chinese medicine preparation for the treatment of chronic hepatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Folium Malloti Apeltae 53 ~ 63 parts of Herba stellariae mediaes 43 ~ 53 portions of Herba Xanthiis 43 ~ 53 parts of Herba senecionis nemorensis 41 ~ 50 parts
Spora Lygodii 38 ~ 48 parts of Radix Bupleuri 36 ~ 45 parts of Fructus Schisandrae Chinensis 33 ~ 43 portions of Herba Apii graveolentis 31 ~ 40 parts
River cypress 31 ~ 40 parts of Rhizoma Paridis 28 ~ 38 parts of Herba Dichodraees 28 ~ 38 parts of Maifanitums 25 ~ 36 parts
Rhizoma Curculiginis 23 ~ 33 parts of ligustrum sinenses 21 ~ 33 parts of Radix Achyranthis Bidentataes 19 ~ 30 parts of Bulbus Allii Macrostemonis 17 ~ 25 parts.
4. a kind of Chinese medicine preparation for the treatment of chronic hepatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Folium Malloti Apeltae 58 parts of Herba stellariae mediaes 48 portions of Herba Xanthiis 48 parts of Herba senecionis nemorensis 46 parts
Spora Lygodii 43 parts of Radix Bupleuri 41 parts of Fructus Schisandrae Chinensis 38 portions of Herba Apii graveolentis 36 parts
River cypress 36 parts of Rhizoma Paridis 33 parts of Herba Dichodraees 33 parts of Maifanitums 31 parts
Rhizoma Curculiginis 28 parts of ligustrum sinenses 27 parts of Radix Achyranthis Bidentataes 24 parts of Bulbus Allii Macrostemonis 21 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of chronic hepatitis, it is characterized in that: comprise following processing step:
(1) Folium Malloti Apeltae, Herba Xanthii, Herba senecionis nemorensis, Spora Lygodii, Fructus Schisandrae Chinensis, Rhizoma Paridis, Herba Dichodrae, ligustrum sinense and Radix Achyranthis Bidentatae are cleaned, put into container, add the distilled water of 8 ~ 12 times amount, soak after 4 ~ 5 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 50 DEG C is the thick paste of 1.10 ~ 1.14, for subsequent use;
(2) Herba stellariae mediae, Herba Apii graveolentis and Bulbus Allii Macrostemonis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) by Radix Bupleuri decontamination, clean, section, dries, is placed in container, mixes thoroughly with vinegar, puts in pot to fry with slow fire to exhaust and micro-dry to vinegar, takes out, dries, be placed in mortar, grind into powder, must be 180 object fine powders for subsequent use;
(4) river cypress, Maifanitum and Rhizoma Curculiginis decontamination are dried, be placed in mortar and grind into powder, 160 object fine powders must be, for subsequent use;
(5) made for above-mentioned steps (1) ~ (4) thick paste, juice and fine powder are mixed, make capsule, obtain the Chinese medicine preparation of described treatment chronic hepatitis.
CN201410103800.6A 2014-03-19 2014-03-19 A kind of Chinese medicine preparation and preparation method for the treatment of chronic hepatitis Expired - Fee Related CN103845583B (en)

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