CN103800883A - Drug for treating distention and fullness and preparation method thereof - Google Patents

Drug for treating distention and fullness and preparation method thereof Download PDF

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CN103800883A
CN103800883A CN201410062398.1A CN201410062398A CN103800883A CN 103800883 A CN103800883 A CN 103800883A CN 201410062398 A CN201410062398 A CN 201410062398A CN 103800883 A CN103800883 A CN 103800883A
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fructus
rhizoma
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impurity
dries
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CN103800883B (en
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储可英
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Abstract

The invention discloses a drug for treating distention and fullness and a preparation method thereof. The drug is mainly prepared from the following crude drugs: rheum officinale, astragalus membranaceus, pinellia ternate, ginger, liquorice, rhizoma alismatis, inula flower, mangnolia officinalis, medicated leaven, fructus aurantii and the like according to a certain weight ratio. The drug disclosed by the invention has the functions of regulating vital energy and tonifying the stomach, and dissolving lumps and resolving masses, and is rapid to take effect, good in curative effect and free of recurrence after distention and fullness are cured when being applied to treatment of distention and fullness.

Description

A kind of medicine for the treatment of feeling of fullness and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of feeling of fullness and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Feeling of fullness is by invasion of pathogenic factor from the exterior into the interior, eating and drinking without temperance, stagnation of phlegm-damp, disorder of emotion, weakness of the spleen and stomach etc. cause dysfunction of spleen and stomach, disorder in ascending and descending, gastric qi be jammed form with breast gastral cavity painful abdominal mass fill up vexed relax, the softness of pressing, pressure not bitterly, depending on a kind of diseases of spleen-stomach that is main clinical characteristics without the shape swelling.Because current Western medicine cannot effectively be treated feeling of fullness, there is great demand to the Chinese medicine of rapid, effective treatment feeling of fullness in people therefore, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, has finally found the medicine of effective treatment feeling of fullness, thereby has completed the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment feeling of fullness.
Another object of the present invention has just been to provide the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select Radix Et Rhizoma Rhei, the Radix Astragali, the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Radix Glycyrrhizae, Rhizoma Alismatis, Flos Inulae, Cortex Magnoliae Officinalis, Massa Medicata Fermentata, Fructus Aurantii, Semen Trichosanthis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Corydalis, Fructus Citri Sarcodactylis, Radix Pseudostellariae, Aspongopus, Fructus Evodiae, Caulis Bambusae In Taenia, Ramulus Cinnamomi, Semen Pruni, Fructus Citri, Herba Asari, Semen Alpiniae Katsumadai, Herba speranskiae tuberculatae, Endothelium Corneum Gigeriae Galli, Folium Eriobotryae, Fructus Amomi, Fructus Mume, Pericarpium Citri Reticulatae, Herba Scutellariae Barbatae, Fructus Crataegi, Flos Caryophylli medicine to combine preparation, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat feeling of fullness.Wherein select Radix Et Rhizoma Rhei to be because its nature and flavor hardship, cold enters stomach, large intestine, liver footpath, have the poison of purging heat, removing mass is stagnant, the function of clots absorbing blood, controls excess-heat constipation, and delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi , lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Select the Radix Astragali to be because its nature and flavor are sweet, tepor, enters lung, spleen channel, raw with the useful consolidating superficial resistance of defending, inducing diuresis to remove edema, and poison holding, the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle is not burst or is burst and hold back for a long time; Process by the function that has invigorating middle warmer benefit, control internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, there is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass, controls damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enters lung, stomach, spleen channel, deliver, and cold expelling, preventing or arresting vomiting, opens the function of expectorant, the wind and cold that cures cold, vomiting, phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Radix Glycyrrhizae to be because its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, processs use, controls weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus , Jing Epilepsy; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, and ulcer sores, separates poison of drug and alimentary toxicosis.Select Rhizoma Alismatis to be because its nature and flavor are sweet, cold, enter urinary bladder channel, there is diuretic, eliminating dampness by diuresis, the function expelling the heat-evil, controls dysuria, and edema anus is full, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Select Flos Inulae to be because its nature and flavor are salty, temperature, enters lung, liver, stomach warp, has expectorant, the therapeutic method to keep the adverse QI flowing downwards, and softening the hard mass, the function of row water, controls in the heart expectorant knot, the lower distension of the side of body, cough with asthma, singultus, saliva is as shellac varnish, epigastric oppression and rigidity, eructation unrelieved, extensive abdominal edema.Selecting Cortex Magnoliae Officinalis is that temperature, enters spleen, stomach, large intestine channel, has warming middle-JIAO because of its nature and flavor toil, the therapeutic method to keep the adverse QI flowing downwards, and dampness, the function of expectorant, controls breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Select Massa Medicata Fermentata to be because its nature and flavor sweet, acrid, warm enters upright stone tablet, stomach warp, have invigorating the spleen and regulating the stomach, the function helping digestion in adjusting, controls retention of food and drink, feeling of stuffiness in chest abdominal distention, and vomiting dysentery, postnatal blood stasis stomachache, children's's enlarged abdomen is hard long-pending.Select Fructus Aurantii to be because its nature and flavor toil, cool.Enter lung, spleen, large intestine channel.Dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select Semen Trichosanthis to be because its nature and flavor are sweet, cold, return lung, stomach, large intestine channel, there is moistening the lung and resolving phlegm, the function of laxation relieving constipation, controls cough caused by dryness expectorant glutinous, dryness of the intestine constipation.Selecting the Rhizoma Atractylodis Macrocephalae is because its property bitter but sweet flavor, and temperature, enters spleen, stomach warp, has spleen reinforcing, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.Select Rhizoma Corydalis to be because its nature and flavor are arduous, temperature, enters liver, stomach warp, invigorates blood circulation, and dissipating blood stasis, regulates the flow of vital energy, and the function of pain relieving is controlled all pains of trusted subordinate's waist knee joint, menoxenia , mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.Select Fructus Citri Sarcodactylis, different name Fructus Citri Sarcodactylis, Bergamot, be because the arduous acid of its nature and flavor, and temperature, enters liver, stomach warp, regulates the flow of vital energy, and the function of reducing phlegm, treats for stomachache, coerce swollen, vomiting, dysphagic, phlegm retention cough with asthma, and relieving the effect of alcohol.Selecting Radix Pseudostellariae is that tepor, enters the heart, spleen, lung three warps, has the function of tonifying the lung, spleen invigorating, controls cough due to deficiency of the lung because of its nature and flavor sweetness and bitterness, insufficiency of the spleen lack of appetite, and cardiopalmus order antiperspirant, spirit is tired.Select Aspongopus to be because its nature and flavor are salty, temperature, enters liver, kidney channel, has regulating QI to relieve pain, and the function of warming middle-JIAO tonifying YANG is controlled the chest and diaphragm stagnation of QI, and gastralgia painful abdominal mass is vexed, and spleen deficiency of the kidney is damaged, and waist knee joint is miserable, sexual impotence.Select Fructus Evodiae to be because its nature and flavor are arduous, temperature, poisonous, enter liver, stomach warp, there is warming middle-JIAO, pain relieving, regulates the flow of vital energy, the function of dampness, stopping vomiting is against acid regurgitation, headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.Select Caulis Bambusae In Taenia to be because its nature and flavor are sweet, cool, enter stomach, gallbladder meridian, have heat clearing away, removing heat from blood, reduces phlegm, and the function of emesis is controlled dysphoria with smothery sensation vomiting, singultus, and expectorant heat syndrome cough is breathed heavily, spit blood, and epistaxis, metrorrhagia, malignant histocytosis, fetal movement , Jing Epilepsy.Selecting Ramulus Cinnamomi is that temperature, enters bladder, the heart, lung meridian, has diaphoresis expelling pathogenic factors from muscles because of its property acrid-sweet flavor, and the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Select Semen Pruni to be because its nature and flavor are arduous sweet, flat, enter spleen, intestine and small intestine warp, have and moisturize, laxation, the therapeutic method to keep the adverse QI flowing downwards, the function of diuretic, controls QI stagnation of the large intestine, dry puckery obstructed, dysuria, extensive abdominal edema, extremity edema, beriberi.Select Fructus Citri to be because its nature and flavor are arduous sour, temperature, enters liver, lung, spleen channel, regulate the flow of vital energy, and Shu Yu, expectorant, the function of sharp diaphragm, the distension that treats for stomachache, cough due to fluid-retention gas is stopped up, the few food of the sound of vomiting of vomitting.Select Herba Asari to be because its nature and flavor are pungent, temperature, enters lung, kidney channel, dispel the wind, and cold expelling, row water, opens the function of stealing, and controls air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Select Semen Alpiniae Katsumadai to be because its nature and flavor are pungent, temperature, enters spleen, stomach warp, has warming middle-JIAO, cold relieving, and circulation of qi promoting, the function of dampness, controls trusted subordinate's cold type of pain, feeling of fullness dyspepsia, dysphagia and regurgitation, cold-damp is vomited and diarrhoea, and phlegm retention is gathered.Select Herba speranskiae tuberculatae to be because its property and flavor of peppery and warm has expelling wind and removing dampness, the function of promoting blood circulation to remove obstruction in the collateral, dispelling the wind and dampness pathogens arthralgia, dropsy, traumatic injury, toothache, eczema.Select Endothelium Corneum Gigeriae Galli to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, control stagnantly, the function of strengthening the spleen and stomach, controls food stagnation distension, vomiting regurgitation, and dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.Selecting Folium Eriobotryae is because its nature and flavor hardship, cool, attaches to the lung and stomach meridians, and has lung heat clearing stomach function regulating, and lowering the adverse-rising QI to resolve phlegm, controls lung-heat phlegmatic cough, hemoptysis, epistaxis, the gastric heat sound of vomiting of vomitting.Select Fructus Amomi to be because its nature and flavor are pungent, temperature, enters spleen, stomach warp, has in circulation of qi promoting tune, and stomach function regulating, the function of being amusing, control stomachache painful abdominal mass swollen, and anorexia dyspepsia, chokes every vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.Selecting Fructus Mume is that temperature, enters liver because of its nature and flavor acid, spleen, and lung, large intestine channel, has convergence to promote the production of body fluid, and the function of relieving colic caused by ascaris anthelmintic, controls chronic cough, deficiency-heat excessive thirst, chronic malaria, dysentery, has blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, ancylostomiasis, psoriasis, bulbar conjunctiva polyp.Selecting Pericarpium Citri Reticulatae is that temperature, returns lung, spleen channel, has regulating qi-flowing for strengthening spleen because of its nature and flavor hardship, pungent, and the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Select Herba Scutellariae Barbatae to be because its nature and flavor hardship is cold, have heat clearing away, the function of removing toxic substances, controls laryngopharynx swelling and pain, scalds traumatic injury, eczema.Select Fructus Crataegi to be because its nature and flavor acid is sweet, tepor, enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, taenifugal function, controls meat Ji , mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, puerperal after-pains, lochiorrhea, children's's breast food is stagnated.Select Flos Caryophylli to be because its nature and flavor are pungent, temperature, enters stomach, spleen, kidney channel, has warming middle-JIAO, warming the kidney, and the function of sending down the abnormal ascending QI, controls singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, tinea disease.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight.
Radix Et Rhizoma Rhei 5-10g Radix Astragali 10-15g Rhizoma Pinelliae 5-12g
Rhizoma Zingiberis Recens 10-20g Radix Glycyrrhizae 8-18g Rhizoma Alismatis 10-15g
Flos Inulae 10-20g Cortex Magnoliae Officinalis 12-22g Massa Medicata Fermentata 15-25g
Fructus Aurantii 6-16g Semen Trichosanthis 12-20g Rhizoma Atractylodis Macrocephalae 5-12g
Rhizoma Corydalis 10-20g Fructus Citri Sarcodactylis 6-15g Radix Pseudostellariae 10-20g
Aspongopus 4-12g Fructus Evodiae 6-15g Caulis Bambusae In Taenia 5-10g
Ramulus Cinnamomi 8-16g Semen Pruni 8-15g Fructus Citri 10-20g
Herba Asari 10-20g Semen Alpiniae Katsumadai 25-35g Herba speranskiae tuberculatae 12-20g
Endothelium Corneum Gigeriae Galli 5-12g Folium Eriobotryae 8-16g Fructus Amomi 6-15g
Fructus Mume 8-18g Pericarpium Citri Reticulatae 10-20g Herba Scutellariae Barbatae 25-35g
Fructus Crataegi 15-25g Flos Caryophylli 5-12g.
Be preferably:
Radix Et Rhizoma Rhei 6g Radix Astragali 15g Rhizoma Pinelliae 9g
Rhizoma Zingiberis Recens 12g Radix Glycyrrhizae 12g Rhizoma Alismatis 15g
Flos Inulae 15g Cortex Magnoliae Officinalis 15g Massa Medicata Fermentata 20g
Fructus Aurantii 10g Semen Trichosanthis 15g Rhizoma Atractylodis Macrocephalae 6g
Rhizoma Corydalis 15g Fructus Citri Sarcodactylis 9g Radix Pseudostellariae 12g
Aspongopus 5g Fructus Evodiae 8g Caulis Bambusae In Taenia 6g
Ramulus Cinnamomi 10g Semen Pruni 9g Fructus Citri 12g
Herba Asari 15g Semen Alpiniae Katsumadai 30g Herba speranskiae tuberculatae 15g
Endothelium Corneum Gigeriae Galli 8g Folium Eriobotryae 10g Fructus Amomi 9g
Fructus Mume 9g Pericarpium Citri Reticulatae 12g Herba Scutellariae Barbatae 30g
Fructus Crataegi 20g Flos Caryophylli 8g.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stews to moisten to inside and outside humidity evenly, cuts into slices or is cut into small pieces, dries;
2, the Radix Astragali: choose clean impurity, remove residual root head and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
3, the Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
4, Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;
5, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, dry;
6, Rhizoma Alismatis: choose decontamination, big or small stepping, is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section, dries;
7, Flos Inulae: choose clean impurity, except destemming leaf, sieve removes earth;
8, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding, dries;
9, Massa Medicata Fermentata: get wheat bran and sprinkle evenly in heat pot, the cigarette of having waited, pours Massa Medicata Fermentata into, fries to yellow, takes out, and sieve removes wheat bran, cools;
10, Fructus Aurantii: remove flesh, core, clean, slightly soak, pull out, soften, can pinch doubling with hands time, section, dries;
11, Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;
12, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
13, Rhizoma Corydalis: choose decontamination, be soaked in water, clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
14, Fructus Citri Sarcodactylis: choose decontamination, after water spray profit, chopping, dries;
15, Radix Pseudostellariae: extract fibrous root, dry;
16, Aspongopus: choose clean impurity, sieve removes earth, or by the micro-stir-fry use of slow fire;
17, Fructus Evodiae: get crude drug, remove fruit stem, branch and impurity, sieve removes chip;
18, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off ash bits, be kneaded into little group or cutting;
19, Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;
20, Semen Pruni: sieve removes spare, washes in a pan only, chooses clean impurity and broken shell, dries, and the used time smashs to pieces;
21, Fructus Citri: get crude drug, remove impurity, wash quickly is clean, slightly profit, shredding, cold drying, sieve removes chip;
22, Herba Asari: Ex-all impurity, water spray profit, cutting in time, dries;
23, Semen Alpiniae Katsumadai: choose clean impurity, shell and get core, the used time smashs to pieces;
24, Herba speranskiae tuberculatae: gather summer, dries;
25, Endothelium Corneum Gigeriae Galli: choose decontamination, rinse and dry;
26, Folium Eriobotryae: brush away fine hair, wash, slightly profit, shredding, dries;
27, Fructus Amomi: choose decontamination and shell, smash to pieces;
28, Fructus Mume: choose clean impurity, sieve dedust bits, clean, and dry;
29, Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, softens, and shredding, dries or cold drying, sieve dedust bits;
30, Herba Scutellariae Barbatae: remove impurity, clean, slightly profit, cutting, dry;
31, Fructus Crataegi: choose clean impurity, sieve enucleation;
32, Flos Caryophylli: look for decontamination, bennet, sieve dedust bits, the used time smashs to pieces.
Two, preparation
1, the Radix Et Rhizoma Rhei of described weight, the Radix Astragali, the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Radix Glycyrrhizae, Rhizoma Alismatis, Flos Inulae, Cortex Magnoliae Officinalis, Massa Medicata Fermentata, Fructus Aurantii, Semen Trichosanthis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Corydalis, Fructus Citri Sarcodactylis, Radix Pseudostellariae, Aspongopus, Fructus Evodiae, Caulis Bambusae In Taenia, Ramulus Cinnamomi, Semen Pruni, Fructus Citri, Herba Asari, Semen Alpiniae Katsumadai, Herba speranskiae tuberculatae, Endothelium Corneum Gigeriae Galli, Folium Eriobotryae, Fructus Amomi, Fructus Mume, Pericarpium Citri Reticulatae, Herba Scutellariae Barbatae, Fructus Crataegi, Flos Caryophylli are decocted with water twice, 6 times of amounts for the first time add water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time.
2, the medicinal residues after filtering are for the first time added water 4 times and measured, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time.
3, merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 4 doses and takes.
Medicine of the present invention has dissolving lump and resolving mass, and the function of the stomach reinforcing of regulating the flow of vital energy is used for the treatment of feeling of fullness instant effect, good effect.Further set forth below the beneficial effect of medicine of the present invention by test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get 30 of West Germany rabbits, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit activities, diet are normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 100 examples for medical treatment.
2, diagnostic criteria
(1) with gastral cavilty painful abdominal mass plug, full vexed not relaxing for main clinical manifestation, the softness that its painful abdominal mass is pressed, pressure not bitterly, depending on without the shape swelling;
(2) often full vexed with chest and diaphragm, diet reduces, and obtains food swollen, and belch relaxes and waits disease;
(3) fall ill with increase the weight of often relevant with the inducement such as diet, feelings will, daily life, changes in temperature imbalance;
(4) mostly be chronic onset, time heavy when light, outbreak repeatedly, touching difficulty more;
(5) fibergastroscopy, upper digestive tract K ray examination, gastric analysis etc. is abnormal, contributes to the diagnosis of primary disease.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, every day 2 times, each 1 dose 20 days is a course for the treatment of, takes continuously 2 courses for the treatment of.
4, efficacy assessment standard
Effective: the recovery from illness of feeling of fullness symptom, recovers normal;
Take a turn for the better: feeling of fullness symptom alleviates, progressively take a turn for the better;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
Figure 2014100623981100002DEST_PATH_IMAGE001
In above-mentioned treatment, by Drug therapy feeling of fullness patient of the present invention 100 examples, effective 80 examples of result, obvious effective rate is 80%, 7 examples that take a turn for the better, and improvement rate is 7%, invalid 13 examples, total effective rate is 87%.

Claims (3)

1. a medicine for the treatment of feeling of fullness, is characterized in that: it is to be made up of the crude drug in following weight range:
Radix Et Rhizoma Rhei 5-10g Radix Astragali 10-15g Rhizoma Pinelliae 5-12g
Rhizoma Zingiberis Recens 10-20g Radix Glycyrrhizae 8-18g Rhizoma Alismatis 10-15g
Flos Inulae 10-20g Cortex Magnoliae Officinalis 12-22g Massa Medicata Fermentata 15-25g
Fructus Aurantii 6-16g Semen Trichosanthis 12-20g Rhizoma Atractylodis Macrocephalae 5-12g
Rhizoma Corydalis 10-20g Fructus Citri Sarcodactylis 6-15g Radix Pseudostellariae 10-20g
Aspongopus 4-12g Fructus Evodiae 6-15g Caulis Bambusae In Taenia 5-10g
Ramulus Cinnamomi 8-16g Semen Pruni 8-15g Fructus Citri 10-20g
Herba Asari 10-20g Semen Alpiniae Katsumadai 25-35g Herba speranskiae tuberculatae 12-20g
Endothelium Corneum Gigeriae Galli 5-12g Folium Eriobotryae 8-16g Fructus Amomi 6-15g
Fructus Mume 8-18g Pericarpium Citri Reticulatae 10-20g Herba Scutellariae Barbatae 25-35g
Fructus Crataegi 15-25g Flos Caryophylli 5-12g.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Et Rhizoma Rhei 6g Radix Astragali 15g Rhizoma Pinelliae 9g
Rhizoma Zingiberis Recens 12g Radix Glycyrrhizae 12g Rhizoma Alismatis 15g
Flos Inulae 15g Cortex Magnoliae Officinalis 15g Massa Medicata Fermentata 20g
Fructus Aurantii 10g Semen Trichosanthis 15g Rhizoma Atractylodis Macrocephalae 6g
Rhizoma Corydalis 15g Fructus Citri Sarcodactylis 9g Radix Pseudostellariae 12g
Aspongopus 5g Fructus Evodiae 8g Caulis Bambusae In Taenia 6g
Ramulus Cinnamomi 10g Semen Pruni 9g Fructus Citri 12g
Herba Asari 15g Semen Alpiniae Katsumadai 30g Herba speranskiae tuberculatae 15g
Endothelium Corneum Gigeriae Galli 8g Folium Eriobotryae 10g Fructus Amomi 9g
Fructus Mume 9g Pericarpium Citri Reticulatae 12g Herba Scutellariae Barbatae 30g
Fructus Crataegi 20g Flos Caryophylli 8g.
3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stews to moisten to inside and outside humidity evenly, cuts into slices or is cut into small pieces, dries;
(2) Radix Astragali: choose clean impurity, remove residual root head and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
(3) Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
(4) Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;
(5) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, dry;
(6) Rhizoma Alismatis: choose decontamination, big or small stepping, is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section, dries;
(7) Flos Inulae: choose clean impurity, except destemming leaf, sieve removes earth;
(8) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding, dries;
(9) Massa Medicata Fermentata: get wheat bran and sprinkle evenly in heat pot, the cigarette of having waited, pours Massa Medicata Fermentata into, fries to yellow, takes out, and sieve removes wheat bran, cools;
(10) Fructus Aurantii: remove flesh, core, clean, slightly soak, pull out, soften, can pinch doubling with hands time, section, dries;
(11) Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;
(12) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
(13) Rhizoma Corydalis: choose decontamination, be soaked in water, clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
(14) Fructus Citri Sarcodactylis: choose decontamination, after water spray profit, chopping, dries;
(15) Radix Pseudostellariae: extract fibrous root, dry;
(16) Aspongopus: choose clean impurity, sieve removes earth, or by the micro-stir-fry use of slow fire;
(17) Fructus Evodiae: get crude drug, remove fruit stem, branch and impurity, sieve removes chip;
(18) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off ash bits, be kneaded into little group or cutting;
(19) Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;
(20) Semen Pruni: sieve removes spare, washes in a pan only, chooses clean impurity and broken shell, dries, and the used time smashs to pieces;
(21) Fructus Citri: get crude drug, remove impurity, wash quickly is clean, slightly profit, shredding, cold drying, sieve removes chip;
(22) Herba Asari: Ex-all impurity, water spray profit, cutting in time, dries;
(23) Semen Alpiniae Katsumadai: choose clean impurity, shell and get core, the used time smashs to pieces;
(24) Herba speranskiae tuberculatae: gather summer, dries;
(25) Endothelium Corneum Gigeriae Galli: choose decontamination, rinse and dry;
(26) Folium Eriobotryae: brush away fine hair, wash, slightly profit, shredding, dries;
(27) Fructus Amomi: choose decontamination and shell, smash to pieces;
(28) Fructus Mume: choose clean impurity, sieve dedust bits, clean, and dry;
(29) Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, softens, and shredding, dries or cold drying, sieve dedust bits;
(30) Herba Scutellariae Barbatae: remove impurity, clean, slightly profit, cutting, dry;
(31) Fructus Crataegi: choose clean impurity, sieve enucleation;
(32) Flos Caryophylli: look for decontamination, bennet, sieve dedust bits, the used time smashs to pieces;
(2) preparation
(1) Radix Et Rhizoma Rhei of described weight, the Radix Astragali, the Rhizoma Pinelliae, Rhizoma Zingiberis Recens, Radix Glycyrrhizae, Rhizoma Alismatis, Flos Inulae, Cortex Magnoliae Officinalis, Massa Medicata Fermentata, Fructus Aurantii, Semen Trichosanthis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Corydalis, Fructus Citri Sarcodactylis, Radix Pseudostellariae, Aspongopus, Fructus Evodiae, Caulis Bambusae In Taenia, Ramulus Cinnamomi, Semen Pruni, Fructus Citri, Herba Asari, Semen Alpiniae Katsumadai, Herba speranskiae tuberculatae, Endothelium Corneum Gigeriae Galli, Folium Eriobotryae, Fructus Amomi, Fructus Mume, Pericarpium Citri Reticulatae, Herba Scutellariae Barbatae, Fructus Crataegi, Flos Caryophylli are decocted with water twice, 6 times of amounts for the first time add water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time;
(2) medicinal residues after filtering are for the first time added water 4 times and measured, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time;
(3) merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 4 doses and takes.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105535918A (en) * 2016-02-18 2016-05-04 成都市飞龙水处理技术研究所青白江第一分所 Oral medicine for treating distention and fullness and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101874889A (en) * 2010-04-23 2010-11-03 泰一和浦(北京)中医药研究院有限公司 Chinese medicinal composition for treating gastric stuffiness and preparation method thereof
CN103566346A (en) * 2013-10-22 2014-02-12 王振友 Drug for treating elderly abdominal distension and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101874889A (en) * 2010-04-23 2010-11-03 泰一和浦(北京)中医药研究院有限公司 Chinese medicinal composition for treating gastric stuffiness and preparation method thereof
CN103566346A (en) * 2013-10-22 2014-02-12 王振友 Drug for treating elderly abdominal distension and preparation method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
张彩玲: "慢性萎缩性胃炎中医治疗进展", 《江西中医药》, no. 02, 21 April 1997 (1997-04-21), pages 55 - 57 *
张荣: "香砂六君子汤合黄芪建中汤加减治疗慢性胃炎76例", 《中国中医药信息杂志》, no. 11, 15 November 2007 (2007-11-15), pages 74 *
沈开金: "《常见胃肠病中医药诊治》", 31 May 2006, article "常见胃肠病中医药诊治" *
贾秀霞: "香砂积术丸治疗慢性胃炎50例", 《浙江中西医结合杂志》, no. 01, 10 January 1997 (1997-01-10), pages 47 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105535918A (en) * 2016-02-18 2016-05-04 成都市飞龙水处理技术研究所青白江第一分所 Oral medicine for treating distention and fullness and preparation method thereof

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