CN103800768A - Traditional Chinese medicinal composition for preventing and treating coccidiosis of poultry and preparation method thereof - Google Patents
Traditional Chinese medicinal composition for preventing and treating coccidiosis of poultry and preparation method thereof Download PDFInfo
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- CN103800768A CN103800768A CN201210451771.3A CN201210451771A CN103800768A CN 103800768 A CN103800768 A CN 103800768A CN 201210451771 A CN201210451771 A CN 201210451771A CN 103800768 A CN103800768 A CN 103800768A
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Abstract
The invention relates to a traditional Chinese medicinal composition for preventing and treating coccidiosis of poultry. The composition comprises the following components in parts by weight: 10-30 parts of stemona, 5-15 parts of rhizoma dryopteris crassirhizomae, 5-15 parts of fructus quisqualis, 5-10 parts of common carpesium fruit, and 5-10 parts of spina date seed. The traditional Chinese medicinal composition does not have toxic or side effect, cannot generate medicine residues, is convenient to use and low in cost, can be used for effective preventing and treating coccidiosis of poultry, and has an effect of calming and resisting stress.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition of preventing and treating coccidiosis of domestic fowls and preparation method thereof.
Background technology
Chicken coccidiosis is one of main fowl diseases.Normal invasion and attack chickling, is often acute breaking out, and cause chickling dysentery, have blood in stool, anemia, so that large quantities of death; The chronic popular growth that hinders, impact weightening finish, and increase food consumption.Coccidiosis is because its curing the disease property is strong, sickness rate is high, harm becomes greatly the large hidden danger that harm aviculture develops in a healthy way.Not yet have good anticoccidial vaccine at present, and conventional coccidiostat often can make coccidiosis produce drug resistance, in the situation that having to strengthen dosage, not only therapeutic effect go fromes bad to worse, and the residual problem of medicine has become more serious later stage harm simultaneously.Therefore, use comparatively safe nontoxicly, the Chinese medicine preparation treatment coccidiosis that is difficult for producing drug resistance just becomes prevention and controls the Optimal action of coccidiosis.More simple and rapid dispensing is simultaneously fed, and is also an important trend of current veterinary drug development.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition of preventing and treating coccidiosis of domestic fowls, the present invention has no side effect, and can not produce drug residue, and easy to use, cost is lower, can effectively prevent and treat coccidiosis of domestic fowls, and has effect of the anti-stress of calming the nerves.
Another object of the present invention is to provide a kind of preparation method of the Chinese medicine composition of preventing and treating coccidiosis of domestic fowls.
The present invention is achieved by the following technical solutions:
Prevent and treat a Chinese medicine composition for coccidiosis of domestic fowls, its Chinese medicine composition component and ratio of weight and number thereof are respectively:
And said composition component and optimum ratio of weight and number thereof are respectively:
Prevent and treat a preparation method for the Chinese medicine composition of coccidiosis of domestic fowls, its step is as follows:
(1) take according to proportioning by weight that the Radix Stemonae, Rhizoma Dryopteris Crassirhizomatis, Fructus Quisqualis, Fructus Carpesii add 8 times of amounts, 6 times of water gagings decoct twice, each 1 hour, decocting liquid obtained A decocting liquid after merging, for subsequent use;
(2) take Semen Ziziphi Spinosae according to weight proportion, after pulverizing, decoct with water 3 times, 2 hours for the first time, for the second time and each 1 hour for the third time, merge decoction liquor, filter, filtrate be concentrated into relative density be 1.20~1.25 and in the time of 80 ℃, add 2mol/L hydrochloric acid solution regulate pH value to 1.0~2.0, be incubated 1 hour, leave standstill 11~13 hours, filter, be precipitated, in precipitation, add 6~8 times of water gagings, form mixed liquor, with 40% sodium hydroxide solution adjust pH to 7.0, the alcoholic solution that to add with the isopyknic concentration of mixed liquor be 90~95% again, be stirred to dissolve, filter, filtrate is used 2mol/L hydrochloric acid solution adjust pH to 2.0, at 55~65 ℃, be incubated 25~35 minutes, leave standstill 10~14 hours, filter, precipitation is washed till pH value to 7.0 with ethanol, wave after most ethanol, merge with gained A decocting liquid in step (1), being concentrated into density reaches 1.20g/ml and obtains B decocting liquid, for subsequent use,
(3) by the spray-dried device of step (2) gained B decocting liquid, at 120 ℃, 250 turn under condition, are spray dried to fine powder, must prevent and treat the Chinese medicine composition finished product of coccidiosis of domestic fowls.
Advantage of the present invention and beneficial effect are:
1, the Radix Stemonae in the Chinese medicine composition of this control coccidiosis of domestic fowls, Rhizoma Dryopteris Crassirhizomatis, Fructus Quisqualis, Fructus Carpesii, as natural Chinese medicine composition, can effectively kill chicken coccidiosis, have no side effect, and can not produce drug resistance and drug residue.
2, the Semen Ziziphi Spinosae composition of the Chinese medicine composition of this control coccidiosis of domestic fowls there is anti-inflammation, the analgesia of calming the nerves, digestant effect, can alleviate other diseases that disease chicken causes because of coccidiosis, contribute to disease chicken to recover, also can greatly reduce the injury of stress to self simultaneously.
3, the preparation method of the Chinese medicine composition of this control coccidiosis of domestic fowls is simple, and cost is lower, and its effective ingredient can easily be absorbed by sick chicken, and the time is short, efficiency is high.
The specific embodiment
The present invention is described in further detail by following examples.It should be noted that: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
The Radix Stemonae in the present invention, Rhizoma Dryopteris Crassirhizomatis, Fructus Quisqualis, Fructus Carpesii, Semen Ziziphi Spinosae all can be bought and obtain on market.
Embodiment 1
Prevent and treat a Chinese medicine composition for coccidiosis of domestic fowls, component and the weight thereof of its compositions are respectively: Radix Stemonae 10kg; Rhizoma Dryopteris Crassirhizomatis 5kg; Fructus Quisqualis 5kg; Fructus Carpesii 5kg; Semen Ziziphi Spinosae 5kg.
Prevent and treat a preparation method for the Chinese medicine composition of coccidiosis of domestic fowls, its step is as follows:
(1) take according to proportioning by weight that the Radix Stemonae, Rhizoma Dryopteris Crassirhizomatis, Fructus Quisqualis, Fructus Carpesii add 8 times of amounts, 6 times of water gagings decoct twice, each 1 hour, decocting liquid obtained A decocting liquid after merging, for subsequent use;
(2) take Semen Ziziphi Spinosae according to weight proportion, after pulverizing, decoct with water 3 times, 2 hours for the first time, for the second time and each 1 hour for the third time, merge decoction liquor, filter, filtrate be concentrated into relative density be 1.20~1.25 and in the time of 80 ℃, add 2mol/L hydrochloric acid solution regulate pH value to 1.0~2.0, be incubated 1 hour, leave standstill 11~13 hours, filter, be precipitated, in precipitation, add 6~8 times of water gagings, form mixed liquor, with 40% sodium hydroxide solution adjust pH to 7.0, the alcoholic solution that to add with the isopyknic concentration of mixed liquor be 90~95% again, be stirred to dissolve, filter, filtrate is used 2mol/L hydrochloric acid solution adjust pH to 2.0, at 55~65 ℃, be incubated 25~35 minutes, leave standstill 10~14 hours, filter, precipitation is washed till pH value to 7.0 with ethanol, wave after most ethanol, merge with gained A decocting liquid in step (1), being concentrated into density reaches 1.20g/ml and obtains B decocting liquid, for subsequent use,
(3) by the spray-dried device of step (2) gained B decocting liquid, at 120 ℃, 250 turn under condition, are spray dried to fine powder, must prevent and treat the Chinese medicine composition finished product of coccidiosis of domestic fowls.
Embodiment 2
Prevent and treat a Chinese medicine composition for coccidiosis of domestic fowls, component and the weight thereof of its compositions are respectively: Radix Stemonae 30kg; Rhizoma Dryopteris Crassirhizomatis 15kg; Fructus Quisqualis 15kg; Fructus Carpesii 10kg; Semen Ziziphi Spinosae 10kg.
The step of its preparation method is with embodiment 1.
Embodiment 3
Prevent and treat a Chinese medicine composition for coccidiosis of domestic fowls, component and the weight thereof of its compositions are respectively: Radix Stemonae 15kg; Rhizoma Dryopteris Crassirhizomatis 8kg; Fructus Quisqualis 8kg; Fructus Carpesii 7kg; Semen Ziziphi Spinosae 8kg.
The step of its preparation method is with embodiment 1.
Embodiment 4
Prevent and treat a Chinese medicine composition for coccidiosis of domestic fowls, component and the weight thereof of its compositions are respectively: Radix Stemonae 22kg; Rhizoma Dryopteris Crassirhizomatis 13kg; Fructus Quisqualis 11kg; Fructus Carpesii 8kg; Semen Ziziphi Spinosae 6kg.
The step of its preparation method is with embodiment 1.
The present invention, in application, can directly drop in disease chicken drinking-water, by chickling 2-5g/ only, becomes chicken 5-10g/ only to count.
Clinical practice test
Two hen houses that chicken coccidiosis feelings occur are chosen in test broiler breeding the field in, cultivate chicken kind, surrounding enviroment are all more consistent in two hen houses.Two hen houses select respectively the present invention and the personal ball dysentery spirit of chicken house to carry out contrast therapy test, treatment before with treatment 5 days after result as follows:
Test group administration of the present invention is after five days, cure rate is apparently higher than matched group, mortality rate obviously reduces, sick chicken is the sick chicken poor growth of matched group during one's sickness, the sick chicken daily gain of test group of the present invention maintains health level substantially, for 2 times of matched group daily gain, sick chicken is not caused heavy losses to raiser during one's sickness.The present invention can effectively prevent and treat coccidiosis of domestic fowls.
Claims (3)
3. a preparation method for the Chinese medicine composition of control coccidiosis of domestic fowls as claimed in claim 1, is characterized in that: the step of this preparation method is as follows:
(1) take according to proportioning by weight that the Radix Stemonae, Rhizoma Dryopteris Crassirhizomatis, Fructus Quisqualis, Fructus Carpesii add 8 times of amounts, 6 times of water gagings decoct twice, each 1 hour, decocting liquid obtained A decocting liquid after merging, for subsequent use;
(2) take Semen Ziziphi Spinosae according to weight proportion, after pulverizing, decoct with water 3 times, 2 hours for the first time, for the second time and each 1 hour for the third time, merge decoction liquor, filter, filtrate be concentrated into relative density be 1.20~1.25 and in the time of 80 ℃, add 2mol/L hydrochloric acid solution regulate pH value to 1.0~2.0, be incubated 1 hour, leave standstill 11~13 hours, filter, be precipitated, in precipitation, add 6~8 times of water gagings, form mixed liquor, with 40% sodium hydroxide solution adjust pH to 7.0, the alcoholic solution that to add with the isopyknic concentration of mixed liquor be 90~95% again, be stirred to dissolve, filter, filtrate is used 2mol/L hydrochloric acid solution adjust pH to 2.0, at 55~65 ℃, be incubated 25~35 minutes, leave standstill 10~14 hours, filter, precipitation is washed till pH value to 7.0 with ethanol, wave after most ethanol, merge with gained A decocting liquid in step (1), being concentrated into density reaches 1.20g/ml and obtains B decocting liquid, for subsequent use,
(3) by the spray-dried device of step (2) gained B decocting liquid, at 120 ℃, 250 turn under condition, are spray dried to fine powder, must prevent and treat the Chinese medicine composition finished product of coccidiosis of domestic fowls.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104082533A (en) * | 2014-07-10 | 2014-10-08 | 南宁荣港生物科技有限公司 | Preparation method of anti-stress traditional Chinese herb synbiotics composition for goslings |
CN110404006A (en) * | 2019-09-05 | 2019-11-05 | 湖南宇山玉月农业科技有限公司 | A kind of pharmaceutical composition for treating chicken necrotizing enterocolitis |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104082533A (en) * | 2014-07-10 | 2014-10-08 | 南宁荣港生物科技有限公司 | Preparation method of anti-stress traditional Chinese herb synbiotics composition for goslings |
CN110404006A (en) * | 2019-09-05 | 2019-11-05 | 湖南宇山玉月农业科技有限公司 | A kind of pharmaceutical composition for treating chicken necrotizing enterocolitis |
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Application publication date: 20140521 |