CN103751675B - Be used for the treatment of dyspeptic medicine of pig and preparation method thereof - Google Patents
Be used for the treatment of dyspeptic medicine of pig and preparation method thereof Download PDFInfo
- Publication number
- CN103751675B CN103751675B CN201410040064.4A CN201410040064A CN103751675B CN 103751675 B CN103751675 B CN 103751675B CN 201410040064 A CN201410040064 A CN 201410040064A CN 103751675 B CN103751675 B CN 103751675B
- Authority
- CN
- China
- Prior art keywords
- weight portion
- weight
- medicine
- herba
- pig
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses one and be used for the treatment of dyspeptic medicine of pig and preparation method thereof, medicine comprises following raw medicinal material: Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Herba Carlinae biebersteinii, peppery Jiang Zi, fiber crops cured dry, puckery pears, Sha Jiang, Flos Cleistocalycis Operculati, Cortex Fraxini, Herba desmodii microphylli, Aloe, Pericarpium Citri Reticulatae, Fructus Hordei Germinatus, Radix Gentianae, Massa Medicata Fermentata and Fructus Jujubae.The invention has the beneficial effects as follows: medicine of the present invention, has efficiently the dyspeptic treatment of pig for primary treatment principle with the spleen strengthening and damp drying, the relieving constipation that helps digestion, eliminating heat pathogen by purging the bowels, drug residue free, can increase Abwehrkraft des Koepers, short treating period, act on advantage rapidly.
Description
Technical field
The present invention relates to herbal medicine technical field, particularly one is used for the treatment of dyspeptic medicine of pig and preparation method thereof.
Background technology
Pig dyspepsia, also known as Gaster Sus domestica intestinal catarrh, is the inflammation on gastrointestinal mucosa top layer.So that gastro-intestinal digestion is in disorder, absorption function goes down, loss of appetite or useless absolutely for principal character, by disease through there being acute and chronic dividing, divide gastric catarrh and intestinal catarrh by diseased region.The inflammatory reaction on gastrointestinal tract mucosa top layer, makes digestive organs function be upset, and digestion, the absorption function of gastrointestinal go down, inappetence or absolutely useless.By the process of the course of disease, acute dyspepsia and chronic indigestion can be divided into; By diseased region, can be divided into based on the dyspepsia of harmonization of the stomach small intestinal and the dyspepsia based on large intestine.The cause of disease is most because raising improper initiation, the common flip-flop as the condition of feeding, feedstuff variations in temperature is variable, when time satisfies, famine or feed are too much, feedstuff moldy metamorphism, the feedstuff that feed is too thick and stiff or freezing, silt is mixed with or with noxious substance in feedstuff, drink water unclean, cause digestive function to be upset, the inflammation of gastrointestinal mucosa top layer.Therefore primary disease is also known as getting ill from overeating.The feedstuff of feeding too much containing protein, fat, easily causes pig dyspepsia.Also the Chang Jifa pig dyspepsia such as some infectious disease, febrile disease stomach function regulating intestinal parasitical diseases.
Dyspeptic pig main manifestations power occurs and does not like food, growth retardation, lassitude, happiness drinking-water, halitosis, has tongue fur, sometimes shows stomachache, vomiting.The feces of piglet.Piglet within 10 ages in days is the loose stool of yellow gummy, and minority starts just in yellow water sample loose stool.If comparatively fast fully recover, yellow strip feces can be transferred soon to.As stadium extends, lark viscosity fecal may be transferred to.During the piglet generation dyspepsia of 10 ~ 30 ages in days, most when starting with regard to gray viscosity or watery stools.Lycoperdon polymorphum Vitt or lark strip may be transferred to, finally for spherical and fully recover later.The sick pig of other ages in days, general feces is stiff, sometimes has loose bowels, and is mixed with indigested feedstuff in excrement.Body temperature normally.
Western medical treatment pig dyspepsia, mainly adjusts gastrointestinal function: generally carry out after bowel relieving, as gastrointestinal contents putrefactive fermentation does not weigh, feces not stench time, also can directly carry out.Apply various gastrotonica, feed to, every day 2 times as yeast tablet or rhubarb soda tablet 2 ~ 10 are mixed in a small amount of feedstuff; Or rhei,rhizoma pulveratum 8 grams, gentianae radix pulverata 8 grams, sodium bicarbonate 16 grams is divided into 4 bags, every day 2 times, each 1 bag; Or it is appropriate to add water after smashing to pieces with purple garlic 10 ~ 20 grams, be mixed in a small amount of feedstuff feed to.Piglet can use each 2 ~ 5 grams of lactasinum, pepsin, dilute hydrochloric acid 2 milliliters, and ordinary water 200 milliliters, takes orally after mixing at twice.Desirable artificial salt 3.5 kilograms when sick pig is more, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 1 kilogram is mixed into powder, and mix feed in feedstuff by every each 1 ~ 1.5 gram, double during constipation, piglets is cut down according to the circumstance.2, antiinflammatory antidiarrheal: as sick pig chronic diarrhea or when acutely suffering from diarrhoea, must antiinflammatory antidiarrheal.Sulfaguanidine 0.1 ~ 0.2 gram of (doubling first)/kg body weight divide 3 times take orally; Also furazolidone 0.2 ~ 1 gram can be used, or berberine 0.2 ~ 0.5 gram takes orally, every day 2 times; Aluminium silicate 5 grams, top crust extractum 0.1 gram, amylase 1 gram, point takes orally for 3 times 1 day, or spice is fed and given.For the affected pig of dehydration, should intravenous injection in time 5% Glucose Liquid, ringer's solution or normal saline etc., to maintain body fluid balance.
Western modern medicine treatment pig dyspepsia, although instant effect, cost is higher, and drug residue is large, easily recurrence after curing, meanwhile, along with a large amount of uses of these medicines, remained a large amount of drug toxicities in animal body, when people eat these Carnis Sus domesticas, the life and health of the mankind in serious threat.And Chinese medicine, not only there is the advantage of western modern medicine, also there is the advantage that western modern medicine does not have.China traditional Chinese medicine application time be conceived to entirety, emphasize to regulate allomeric function, improve the premunition of body self, prolonged application is safe and reliable, therefore, in treatment pig dyspepsia, serves more and more important effect because have drawn from nature, and, the medical herbs with severe toxicity is few, uses clinically and compares specification, therefore Chinese herbal medicine can than Chinese patent medicine and Western medicine safer; The side effect of Chinese herbal medicine this three by comparison time minimum.
Summary of the invention
Technical problem to be solved by this invention is to provide one to be used for the treatment of dyspeptic medicine of pig and preparation method thereof, adopts this medicine that the treatment of pig dyspepsia is had to efficient, drug residue free, can increase Abwehrkraft des Koepers, short treating period, acts on advantage rapidly.
In order to realize foregoing invention object, the invention provides one and be used for the treatment of the dyspeptic medicine of pig, described medicine comprises following raw medicinal material: Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Herba Carlinae biebersteinii, peppery Jiang Zi, fiber crops cured dry, puckery pears, Sha Jiang, Flos Cleistocalycis Operculati, Cortex Fraxini, Herba desmodii microphylli, Aloe, Pericarpium Citri Reticulatae, Fructus Hordei Germinatus, Radix Gentianae, Massa Medicata Fermentata and Fructus Jujubae.
Described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 20-30 weight portion, Rhizoma Atractylodis Macrocephalae 20-30 weight portion, Herba Carlinae biebersteinii 10-20 weight portion, peppery Jiang Zi 10-15 weight portion, the cured dry 10-20 weight portion of fiber crops, puckery pears 20-30 weight portion, husky Rhizoma Zingiberis Recens 10-20 weight portion, Flos Cleistocalycis Operculati 10-15 weight portion, Cortex Fraxini 10-20 weight portion, Herba desmodii microphylli 10-20 weight portion, Aloe 20-30 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Fructus Hordei Germinatus 10-15 weight portion, Radix Gentianae 10-20 weight portion, Massa Medicata Fermentata 10-20 weight portion and Fructus Jujubae 20-30 weight portion.
Described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 22-26 weight portion, Rhizoma Atractylodis Macrocephalae 20-25 weight portion, Herba Carlinae biebersteinii 12-18 weight portion, peppery Jiang Zi 12-15 weight portion, the cured dry 16-20 weight portion of fiber crops, puckery pears 23-26 weight portion, husky Rhizoma Zingiberis Recens 13-20 weight portion, Flos Cleistocalycis Operculati 12-15 weight portion, Cortex Fraxini 14-20 weight portion, Herba desmodii microphylli 15-20 weight portion, Aloe 23-26 weight portion, Pericarpium Citri Reticulatae 20-25 weight portion, Fructus Hordei Germinatus 10-13 weight portion, Radix Gentianae 13-20 weight portion, Massa Medicata Fermentata 10-16 weight portion and Fructus Jujubae 20-27 weight portion.
Described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 24 weight portion, the Rhizoma Atractylodis Macrocephalae 23 weight portion, Herba Carlinae biebersteinii 15 weight portion, peppery Jiang Zi 14 weight portion, fiber crops cured dry 17 weight portions, puckery pears 25 weight portion, husky Rhizoma Zingiberis Recens 16 weight portion, Flos Cleistocalycis Operculati 14 weight portion, Cortex Fraxini 17 weight portion, Herba desmodii microphylli 17 weight portion, Aloe 25 weight portion, Pericarpium Citri Reticulatae 23 weight portion, Fructus Hordei Germinatus 12 weight portion, Radix Gentianae 16 weight portion, Massa Medicata Fermentata 13 weight portion and Fructus Jujubae 24 weight portion.
Described medicine also comprises illiteracy Herba caryopteridis nepetaefoliae, Endothelium Corneum Gigeriae Galli, Radix Incarvilleae compactae and Semen Aesculi.
Described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 20-30 weight portion, Rhizoma Atractylodis Macrocephalae 20-30 weight portion, Herba Carlinae biebersteinii 10-20 weight portion, peppery Jiang Zi 10-15 weight portion, the cured dry 10-20 weight portion of fiber crops, puckery pears 20-30 weight portion, husky Rhizoma Zingiberis Recens 10-20 weight portion, Flos Cleistocalycis Operculati 10-15 weight portion, Cortex Fraxini 10-20 weight portion, Herba desmodii microphylli 10-20 weight portion, Aloe 20-30 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Fructus Hordei Germinatus 10-15 weight portion, Radix Gentianae 10-20 weight portion, Massa Medicata Fermentata 10-20 weight portion, Fructus Jujubae 20-30 weight portion, cover Herba caryopteridis nepetaefoliae 10-20 weight portion, Endothelium Corneum Gigeriae Galli 10-20 weight portion, Radix Incarvilleae compactae 10-20 weight portion and Semen Aesculi 10-24 weight portion.
Described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 22-26 weight portion, Rhizoma Atractylodis Macrocephalae 20-25 weight portion, Herba Carlinae biebersteinii 12-18 weight portion, peppery Jiang Zi 12-15 weight portion, the cured dry 16-20 weight portion of fiber crops, puckery pears 23-26 weight portion, husky Rhizoma Zingiberis Recens 13-20 weight portion, Flos Cleistocalycis Operculati 12-15 weight portion, Cortex Fraxini 14-20 weight portion, Herba desmodii microphylli 15-20 weight portion, Aloe 23-26 weight portion, Pericarpium Citri Reticulatae 20-25 weight portion, Fructus Hordei Germinatus 10-13 weight portion, Radix Gentianae 13-20 weight portion, Massa Medicata Fermentata 10-16 weight portion, Fructus Jujubae 20-27 weight portion, cover Herba caryopteridis nepetaefoliae 10-15 weight portion, Endothelium Corneum Gigeriae Galli 15-20 weight portion, Radix Incarvilleae compactae 10-15 weight portion and Semen Aesculi 15-20 weight portion.
Described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 24 weight portion, the Rhizoma Atractylodis Macrocephalae 23 weight portion, Herba Carlinae biebersteinii 15 weight portion, peppery Jiang Zi 14 weight portion, cured dry 17 weight portions of fiber crops, puckery pears 25 weight portion, husky Rhizoma Zingiberis Recens 16 weight portion, Flos Cleistocalycis Operculati 14 weight portion, Cortex Fraxini 17 weight portion, Herba desmodii microphylli 17 weight portion, Aloe 25 weight portion, Pericarpium Citri Reticulatae 23 weight portion, Fructus Hordei Germinatus 12 weight portion, Radix Gentianae 16 weight portion, Massa Medicata Fermentata 13 weight portion, Fructus Jujubae 24 weight portion, cover Herba caryopteridis nepetaefoliae 12 weight portion, Endothelium Corneum Gigeriae Galli 18 weight portion, Radix Incarvilleae compactae 13 weight portion and Semen Aesculi 18 weight portion.
In order to better realize foregoing invention object, present invention also offers a kind of preparation method being used for the treatment of the dyspeptic medicine of pig, described preparation method comprises the following steps: take all raw medicinal materials according to ratio of weight and number, be ground into coarse powder, pulverize further again, cross 100 order ~ 120 mesh sieves, the fine powder amount that enable pass is sieved reaches 30%, collects and obtains fine powder a by the fine powder of sieve; Again the coarse powder not by 100 order ~ 120 mesh sieves is dropped into multi-function extractor to extract twice, first time adds coarse powder 5-10 times amount soak by water 1-2 hour, second time adds coarse powder 4-8 times amount soak by water 1-2 hour, merge twice decocting liquid, filter to get filtrate, heating is concentrated into pasty state, puts into after 80 DEG C, baking oven is dried and cools, grind to form fine powder b, fine powder a and fine powder b is mixed to get drug powder.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: medicine of the present invention, has efficiently the dyspeptic treatment of pig for primary treatment principle with the spleen strengthening and damp drying, the relieving constipation that helps digestion, eliminating heat pathogen by purging the bowels, drug residue free, can increase Abwehrkraft des Koepers, short treating period, act on advantage rapidly.
Detailed description of the invention
Chinese veterinarian thinks, The spleen has the function to transport and transform nutrients: fortune, namely transports conveying, changes, namely digests and assimilates.The spleen has the function to transport and transform nutrients, refers to that spleen has Jiang Shuigu and turns to precise and tiny, and cereal nutrient is transferred the function to each internal organs of whole body.In fact, spleen is exactly the function of digestion to nutrient substance, absorption and transport.The digestion of ingesta and the absorption of nutrient substance, to transfer, be the physiological activity that under multiple internal organs such as taste, liver and gall, intestine and small intestine participate in jointly one is complicated, wherein spleen plays a leading role: the transportation capabilities of spleen mainly rely on temper the lucid yang sending up and the warm effect of spleen sun: the normal function of the spleen tending to ascent." people Na Shuigu, temper and rise " (" three-character medical verses annex internal organs "), " spleen rises and kind mill " (" four holy heart sources "), water paddy enters stomach, entirely relies spleen sun transporting for it.Therefore " spleen has one/sun, and can disappear one/water paddy; Spleen has ten/sun, and can disappear ten/water paddy " (" curing former ").The transportation capabilities of spleen, system say transporting and transforming nutrients from foodstuff, point it, then comprise transporting and transforming nutrients from foodstuff and transformation of body flaud two aspects.
Food is after digesting and assimilating, and its essence of water and grain transferring and loose essence effect and upper defeated in lung again by spleen, injecting heart arteries and veins by lungs turns to QI and blood, then carries whole body by passages through which vital energy circulates, with the nutrition vital organs of the human body, extremity bones of the body collectively, and each histoorgan such as fur, muscles." diet ancestor in stomach, transporting and transforming function of the spleen and stomach of waiting, it is precise and tiny defeated in lung, and lung qi spreads the dirty of each worked as people, foul smell servant intestine and small intestine, and to be taste be parting stove is also " (" doctor Quan Chubian ").In a word, the vital organs of the human body maintain the essence of water and grain required for normal physiological activity, all depend on the transporting effect of spleen.Because diet water paddy is the main source of the necessary nutrient substance of activity of sustaining life after people is born, it is also the material base generating QI and blood.The transporting of diet water paddy is then led by spleen, the spleen being the foundation of acquired constitution thus, source of generating QI and blood.Therefore say: " one has this body, and must provide essence derived from food, paddy enters stomach, spill old in six internal organs gas extremely, and to adjust in the five internal organs blood raw, and people's money think survivor, therefore say the foundation of acquired constitution being the spleen " (" Required Readings for Medical Professionals kidney is congenital spleen is this opinion day after tomorrow ").But " five tastes population, is hidden in stomach, and spleen is its vital essence of trip " (" Plain Questions strange sick opinion "), man taking foodstuff as his major source of life, taste are reservoir of food and drink, thus again cloud The spleen and stomach provide the material basis of the acquired, source of generating QI and blood.This theory, in health-preserving and disease-preventing, has great importance.
The transportation capabilities of spleen are strong, are called traditionally " the strong fortune of temper ".Only have the strong fortune of temper, then the digestive and absorptive functions of body could perfect, and could provide enough nutriment, whole body internal organs just can be made to obtain sufficient nutrition, to maintain normal physiological activity for changing anger, blood, body fluid etc.Otherwise if dysfunction of the spleen in transportation, then the digestive and absorptive functions of body is just therefore not normal, just there will be abdominal distention, loose stool, inappetence so that asthenia, to become thin and the pathological change such as insufficiency of vital energy and blood.
According to above-mentioned theory, the present invention with the spleen strengthening and damp drying, the relieving constipation that helps digestion, eliminating heat pathogen by purging the bowels for Therapeutic Principle, provide one and be used for the treatment of the dyspeptic medicine of pig, comprise Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Herba Carlinae biebersteinii, peppery Jiang Zi, fiber crops cured dry, puckery pears, Sha Jiang, Flos Cleistocalycis Operculati, Cortex Fraxini, Herba desmodii microphylli, Aloe, Pericarpium Citri Reticulatae, Fructus Hordei Germinatus, Radix Gentianae, Massa Medicata Fermentata and Fructus Jujubae.
Wherein, the pharmacological property of each raw medicinal material is as follows:
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
The Rhizoma Atractylodis Macrocephalae: be the dry rhizome of the feverfew Rhizoma Atractylodis Macrocephalae.Return spleen, stomach warp, bitter in the mouth, sweet and warm in nature.Function invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive." medicine origin " records the Rhizoma Atractylodis Macrocephalae " dehumidifying benefit is dry, and middle QI invigorating, warming middle-JIAO, and go in taste wet, except gastric heat, strong taste, enter diet, quench the thirst, antiabortive "; Shennong's Herbal records the Rhizoma Atractylodis Macrocephalae " the sweet temperature of abnormal smells from the patient, nontoxic, control anemofrigid-damp arthralgia, dead flesh, convulsion subcutaneous ulcer, hidroschesis, heat extraction, to help digestion "; " Yaoxing Fu " record the Rhizoma Atractylodis Macrocephalae " sweet in the mouth, temperature, nontoxic.Can rise and can fall, sun also.It is with having four: dredging water passages, has the merit of dehumidifying; Strong taste, have the effect of feed, and assistant Radix Scutellariae has antiabortive energy, and monarch's Fructus Aurantii Immaturus has the wonderful of the painful abdominal mass that disappears ".
Herba Carlinae biebersteinii: sweet acid; Micro-salty; Temperature.Return spleen; Liver; Kidney channel.Function cures mainly: strengthening the spleen and stomach; Replenishing QI and blood; Tune have through.Main insufficiency of the spleen lack of appetite; Dyspepsia; Deficiency of both QI and blood; Asthenic body; Have through uncomfortable.
Peppery Jiang Zi: pungent; Tepor.Function cures mainly: warming middle-JIAO is regulated the flow of vital energy; Relieving dyspepsia.Main epigastric pain; Dyspepsia abdominal distention; Vomiting is had loose bowels.
Fiber crops are cured dry: bitter in the mouth; Cool in nature.Function cures mainly: clearing away heat and promoting diuresis; Invigorating the stomach and promoting digestion.Main urinary system infection; Dyspepsia.
Puckery pears: sweet in the mouth; Acid; Puckery; Slightly warm in nature.Function cures mainly: dyspepsia and intestinal stasis relieving; Regulating qi-flowing for strengthening spleen.Staple food is long-pending to be stagnated; Gastral cavity abdominal distention is educated; Have loose bowels.
Sha Jiang: gas perfume (or spice) is special, and acrid in the mouth is peppery.Function cures mainly circulation of qi promoting warming middle-JIAO, helps digestion, pain relieving.For chest and diaphragm distension, coldness and pain in the epigastrium, diet does not disappear.Husky Rhizoma Zingiberis Recens acrid in the mouth, warm in nature, enter stomach warp; The people trusted subordinate cold type of pain of suitable cold syndrome of the stomach, borborygmus diarrhoea person, poor appetite, anorexia, or the people stopping dyspepsia eats.Compendium of Material Medica: " in warm, ward off communicable subtropical diseases bad odor, control trusted subordinate's cold type of pain, cold-damp cholera.", " book on Chinese herbal medicine converges and says ": " control and stop dyspepsia, all cards of all excessive cold invading middle-JIAO(the spleen and stomach) " has warming spleen and stomach for dispelling cold, appetite-stimulating indigestion-relieving, effect of regulating QI to relieve pain.
Flos Cleistocalycis Operculati: bitter in the mouth; Micro-sweet; Cool in nature.Return lung; Spleen; Stomach warp.Eliminating summer-heat from the exterior, drying, it is stagnant to disappear, anti-inflammatory anti-itch.Alabastrum: cold, fever, bacillary dysentery, acute gastroenteritis, dyspepsia.Root: icterohepatitis.Bark: burn is controlled in external, leprosy, skin pruritus, tinea pedis.Leaf: acute mastitis is controlled in external.
Cortex Fraxini: cure mainly heat clearing and damp drying, liver heat removing and eyesight improving, antiasthmatic-antitussive.For pyretic toxicity dysentery, conjunctival congestion and swelling pain, the raw cataracta of order.
Herba desmodii microphylli: sweet is flat.Function cures mainly: heat clearing away, dampness removing, removing toxic substances.Control urinary system calculus, chronic gastritis, chronic tracheitis, infantile malnutrition, carbuncle carbuncle on the back, hemorrhoid, dermatitis rhus.1. " detailed outline ": " main carbuncle carbuncle on the back.Get leaf and enter drug of topical application use." 2. " Zhiwu Mingshi Tukao ": " Norway applies and controls dermatitis rhus." 3. " Yunnan Chinese herbal medicine ": " anti-inflammation hemostasia, dampness removing dredging collateral.Control kidney, vesical calculus, chronic gastritis, heating."
Aloe: bitter, cold.Return liver, stomach, large intestine channel.Function cures mainly: removing heat from the liver, relieving constipation.For constipation, infantile malnutrition, infantile convulsion; External treatment exudative dermatitis.
Pericarpium Citri Reticulatae: regulating the flow of Qi and the middle Jiao, drying dampness to eliminate phlegm, diuretic relieving constipation.Cure mainly incoordination between the spleen and stomach, abdominal distention, anorexia, vomiting hiccup; Accumulation of phlegm-damp in the lung, cough with copious phlegm, chest and diaphragm is full vexed, the vertigo; Edema, dysuria, constipation; Acute mastitis skin ulcer tinea, middle fish Eriocheir sinensis poison, alcoholism.For diseases such as distension and fullness of the chest and abdomen.The pungent loose logical temperature of Pericarpium Citri tangerinae, fragrant odour, is longer than and regulates the flow of vital energy, and can enter spleen lung, therefore can go loose sluggishness of lung-QI, again can promoting the circulation of QI to alleviate the stagnation in middle-JIAO, gathers around stagnant, chest and diaphragm feeling of fullness and the disease such as stagnation of QI in spleen and stomach, distension and fullness in the abdomen for lung qi.Warm-dryness syndrome is wet and can spleen invigorating circulation of qi promoting, therefore is usually used in the diseases such as retention of dampness in middle-JIAO, gastral cavity abdominal distention are vexed, loose stool greasy fur, can compatibility Rhizoma Atractylodis, Cortex Magnoliae Officinalis is with using.Be good at drying dampness to eliminate phlegm again, be control the conventional key medicine that damp-phlegm stops up lung, abundant expectoration cough, often use together with the Rhizoma Pinelliae, Poria.Reduce for insufficiency of the spleen diet, dyspepsia, and the disease such as nausea and vomiting, dampness and can spleen benefiting and stimulating the appetite, is applicable to the diseases such as weakness of the spleen and stomach, diet minimizings, dyspepsia, loose stool and diarrhea, often and the fit applications such as Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, Poria.Because it can spleen invigorating, can regulate the flow of vital energy again, therefore the assistant being often used as Qi-tonifying drug makes, and can make tonify without causing stagnation, prevent heap soil or fertilizer over and around the roots from holding back and do swollen effect.In addition, Pericarpium Citri tangerinae again can with in, stomach-QI being unable to descend normally, nausea and vomiting can be controlled.
Fructus Hordei Germinatus: form through barley germination, Fructus Hordei Germinatus is put micro-stir-fry extremely yellow in pot, spray clear water, taking-up is dried, and is Fructus Hordei Germinatus (parched to brown).Fructus Hordei Germinatus (parched to brown) has the stagnant merit of invigorating the spleen and regulating the stomach, soothing liver-QIization, is used for the treatment of that food stagnation does not disappear, the disease such as distension and fullness in the abdomen, inappetence, vomiting are had loose bowels.Modern study is thought, in Fructus Hordei Germinatus, rich in starch catabolic enzyme, conversion carbohydrase, esterified enzyme, vitamin B etc., have good digestion-aid effect.
Radix Gentianae: bitter, cold.Return liver, gallbladder meridian.Function cures mainly: heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deaf, hypochondriac pain, bitter taste, convulsion with spasms.
Massa Medicata Fermentata: record according to " the southern regions of the Yunnan Province book on Chinese herbal medicine ", Massa Medicata Fermentata can " be held up taste to enter diet, disappear and stop the food of gastric every place ".Massa Medicata Fermentata is containing volume yeast, and vitamin B group, also containing multiple vitamin B group in cerevisin, therefore Massa Medicata Fermentata has the effect of vitamin B group sample.As appetite stimulator, maintain normal stool function etc.
Fructus Jujubae: there is immunosuppressive action, the ethanol extract of Fructus Jujubae with every day 100mg to rat oral gavage, display Fructus Jujubae has same immunosuppressant with azathioprine; The generation of antibody can be suppressed to atopic diseases.Fructus Jujubae ethanol extract may have inhibitory action to rat reactive antibody, and other effects of inhibitory action are not produced to non-reacted antibody: the two glucoside A of the flavone in Fructus Jujubae, pharmacological evaluation proves have calmness, hypnosis and hypotensive effect, and Fructus Jujubae has the effect increasing cAMP in leukocyte.Fructus Jujubae decoct can reduce the damage of CCl4 to Rabbit Liver.The swimming time of mice can be extended.Nearest report Fructus Jujubae has the proliferation function of anticancer.
Medicine of the present invention also comprises: cover Herba caryopteridis nepetaefoliae, Endothelium Corneum Gigeriae Galli, Radix Incarvilleae compactae and Semen Aesculi.
Cover Herba caryopteridis nepetaefoliae: sweet, temperature.Function cures mainly: help digestion and regulate the flow of vital energy, wind-damp dispelling, promoting blood circulation and stopping pain.Cure mainly dyspepsia, abdominal distention; External treating rheumatic arthritis.
Endothelium Corneum Gigeriae Galli: sweet, cold, return spleen, stomach, small intestinal, urinary bladder channel, for promoting digestion and invigorating the stomach, arresting seminal emission.Endothelium Corneum Gigeriae Galli is containing gastric hormone, keratin, aminoacid and micro-pepsin, amylase etc.After oral Endothelium Corneum Gigeriae Galli powder, the secretory volume of gastric juice, acidity and eupepsy all increase, and stomach motion is strengthened, emptying quickening.Its acid extraction liquid or decoct can accelerate to get rid of radiostrontium from urine.
Radix Incarvilleae compactae: bitter in the mouth; Micro-sweet; Property is put down.Return liver, spleen, lung, stomach four warp.Function cures mainly: heat clearing away; Fresh poison; Dampness; Help digestion.Main heating; Jaundice; Otitis media; Dyspepsia; Stomachache; Abdominal distention constipation.
Semen Aesculi: sweet, temperature.Return liver, stomach warp.Function cures mainly: regulating the flow of QI to ease the stomach, and stomach and alleviating pain.Vexed for breast abdominal distention, gastralgia.
Embodiment 1 medicine 1
Embodiments provide one and be used for the treatment of the dyspeptic medicine of pig, medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 24 weight portion, the Rhizoma Atractylodis Macrocephalae 23 weight portion, Herba Carlinae biebersteinii 15 weight portion, peppery Jiang Zi 14 weight portion, fiber crops cured dry 17 weight portions, puckery pears 25 weight portion, husky Rhizoma Zingiberis Recens 16 weight portion, Flos Cleistocalycis Operculati 14 weight portion, Cortex Fraxini 17 weight portion, Herba desmodii microphylli 17 weight portion, Aloe 25 weight portion, Pericarpium Citri Reticulatae 23 weight portion, Fructus Hordei Germinatus 12 weight portion, Radix Gentianae 16 weight portion, Massa Medicata Fermentata 13 weight portion and Fructus Jujubae 24 weight portion.
Said medicine is obtained by following preparation method: take all raw medicinal materials according to ratio of weight and number, be ground into coarse powder, then pulverize further, and cross 110 mesh sieves, the fine powder amount that enable pass is sieved reaches 30%, collects and obtains fine powder a by the fine powder of sieve; Again the coarse powder not by 110 mesh sieves is dropped into multi-function extractor to extract twice, first time adds coarse powder 8 times amount soak by water 2 hours, second time adds coarse powder 5 times amount soak by water 1 hour, merge twice decocting liquid, filter to get filtrate, heating is concentrated into pasty state, puts into after 80 DEG C, baking oven is dried and cools, grind to form fine powder b, fine powder a and fine powder b is mixed to get drug powder.
The using method of embodiment of the present invention medicine is: be mixed in feedstuff by medicine according to the percentage by weight of feedstuff 2-6%, conveniently feed mode is fed; Or medicine is soluble in water, each 5-8g medicine, every day gavages for 1-3 time.
Embodiment 2 medicine 2
Embodiments provide one and be used for the treatment of the dyspeptic medicine of pig, medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 24 weight portion, the Rhizoma Atractylodis Macrocephalae 23 weight portion, Herba Carlinae biebersteinii 15 weight portion, peppery Jiang Zi 14 weight portion, cured dry 17 weight portions of fiber crops, puckery pears 25 weight portion, husky Rhizoma Zingiberis Recens 16 weight portion, Flos Cleistocalycis Operculati 14 weight portion, Cortex Fraxini 17 weight portion, Herba desmodii microphylli 17 weight portion, Aloe 25 weight portion, Pericarpium Citri Reticulatae 23 weight portion, Fructus Hordei Germinatus 12 weight portion, Radix Gentianae 16 weight portion, Massa Medicata Fermentata 13 weight portion, Fructus Jujubae 24 weight portion, cover Herba caryopteridis nepetaefoliae 12 weight portion, Endothelium Corneum Gigeriae Galli 18 weight portion, Radix Incarvilleae compactae 13 weight portion and Semen Aesculi 18 weight portion.
Said medicine is obtained by following preparation method: take all raw medicinal materials according to ratio of weight and number, be ground into coarse powder, then pulverize further, and cross 120 mesh sieves, the fine powder amount that enable pass is sieved reaches 30%, collects and obtains fine powder a by the fine powder of sieve; Again the coarse powder not by 120 mesh sieves is dropped into multi-function extractor to extract twice, first time adds coarse powder 7 times amount soak by water 2 hours, second time adds coarse powder 6 times amount soak by water 1.5 hours, merge twice decocting liquid, filter to get filtrate, heating is concentrated into pasty state, puts into after 80 DEG C, baking oven is dried and cools, grind to form fine powder b, fine powder a and fine powder b is mixed to get drug powder.
The using method of embodiment of the present invention medicine is: be mixed in feedstuff by medicine according to the percentage by weight of feedstuff 2-6%, conveniently feed mode is fed; Or medicine is soluble in water, each 5-8g medicine, every day gavages for 1-3 time.
Toxicity test
1, acute toxicity test
Require to carry out prerun according to acute toxicity test, find that test medicine cannot measure LD50.Therefore carry out maximum dosage-feeding test in a day.Get above-mentioned mice 40, fasting can't help water after 12 hours, administration group and water matched group is divided at random by body weight, often organize 20, administration group gives the medicinal liquid 0.4ml/10g of the crude drug amount 2.4g/ml concentration of the medicine prepared containing embodiment 1, gavage one day 2 times, make dosage in a day reach symphysis dose 192.0g/kg, water matched group is to the water of equal volume.After each treated animal administration, 5, every box, normal raising, close observation, equal Continuous Observation seven days, the toxic reaction that record may occur and death condition, after administration, mice outward appearance hair color light, behavioral activity is normal, pathologic neural reflex without exception occurs, in seven days, feed is good, and other Novel presentation is seen at end, body weight change no significant difference and none animal dead compared with water matched group, the main organs such as the perusal heart, liver, spleen, lung, kidney, without general pathology changes such as significantly hemorrhage, tissue degeneratiaon, necrosis.Use the medicine of the embodiment of the present invention 2 to carry out above-mentioned test to mice, the test result of result as embodiment 1 medicine is identical.
2, long term toxicity test
The medicine of the embodiment of the present invention 1 presses 10.78,20.35 and 33.48g crude drug/kg continuous use 16 weeks (1.0ml/100g body weight to mice, every day 2 times) and drug withdrawal after 4 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of medicine of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.Use the medicine of the embodiment of the present invention 2 to carry out above-mentioned test to mice, the result of the test of result as embodiment 1 medicine is identical.
Clinical trial
(1) laboratory animal
In May, 2012, Taian Shandong pig farm, the pig morbidity about 600 3 monthly ages of raising, clinical symptoms: appetite subtracts greatly or gives up absolutely, lassitude, happiness drinking-water, Oral symptoms is obvious, halitosis weight, thick fur, mucosa is moist, often feel sick and tell or retch, constipation, feces is stiff, be mixed with indigested feedstuff in excrement, but body temperature is normal.Be indigestion after diagnosing.
(2) test method
Choose 240 ill pigs that the state of an illness is more or less the same as examination animal, be divided into three groups at random, often organize 80, adopt the medicine (embodiment group 1) of the embodiment of the present invention 1, the medicine (embodiment group 2) of embodiment 2 and conventional medicament to treat respectively.Wherein, medicine 1 is mixed in feedstuff according to feedstuff 5% percentage by weight by embodiment group 1, feeds according to normal feed mode; Medicine 2 is mixed in feedstuff according to feedstuff 4% percentage by weight by embodiment group 2, feeds according to normal feed mode; Conventional medicament is selected: rhubarb soda tablet 6 is mixed in a small amount of feedstuff fed to, every day 2 times.Test period is 3-7 days.
(3) criterion of therapeutical effect
Recovery from illness: mental status is good, and appetite, stool hardness, shape and color and oral cavity all recover normal, is judged to be recovery from illness;
Effective: mental status is good, and appetite, feces and oral cavity recover normal substantially, are judged to be effective;
Invalid: after medication, situation does not take a turn for the better.
Wherein, recovery from illness and effective percentage ratio sum count effective percentage.
(4) therapeutic outcome
Therapeutic effect is as shown in table 1, from therapeutic effect, adopts medicine of the present invention to be more than 91% to the dyspeptic treated effect of pig, higher than matched group.
Table 1 therapeutic effect synopsis
Data as can be seen from table 1: compared with matched group, use the Drug therapy swine dyspepsia of the embodiment of the present invention 1 and embodiment 2, have evident in efficacy, that cure rate is high advantage; Find in long-term observation subsequently, embodiment group 1 and embodiment group 2 pig of curing again sickness rate is starkly lower than the pig of matched group.
Concrete case
Case 1
In by the end of December, 2011, and Heze City, Shandong Province pig farmer finds that the situation of eating less or going on a hunger strike appears in 3 growing and fattening pigs of raising, and constipation, is obviously mixed with the food of digestion, lassitude, vomits once in a while, red tongue with yellow fur in feces.Be diagnosed as indigestion, use the medicine of the embodiment of the present invention 1 to treat, be mixed in feedstuff by medicine according to the percentage by weight of feedstuff 6%, conveniently feed mode is fed, and uses 3 days continuously, and all diseases disappear, and pig all recovers normal.
Case 2
In by the end of December, 2011, the feedstuff of certain pig farm owing to feeding moldy metamorphism, causes the piglet about 38 20 ages in days to occur dyspeptic symptom, does not like food, growth retardation, lassitude, happiness drinking-water, halitosis, there is tongue fur, sometimes show stomachache, vomiting feces gray viscosity or watery stools, body temperature is normal.Use the medicine of the embodiment of the present invention 2 to treat, medicine is soluble in water, and each 5g medicine, every day gavages for 2 times, and after using 4 days continuously, 32 piglets are all fully recovered, and continues use 2 days, and other 6 are also recovered normal.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (7)
1. be used for the treatment of the dyspeptic medicine of pig, it is characterized in that, described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 20-30 weight portion, Rhizoma Atractylodis Macrocephalae 20-30 weight portion, Herba Carlinae biebersteinii 10-20 weight portion, peppery Jiang Zi 10-15 weight portion, the cured dry 10-20 weight portion of fiber crops, puckery pears 20-30 weight portion, husky Rhizoma Zingiberis Recens 10-20 weight portion, Flos Cleistocalycis Operculati 10-15 weight portion, Cortex Fraxini 10-20 weight portion, Herba desmodii microphylli 10-20 weight portion, Aloe 20-30 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Fructus Hordei Germinatus 10-15 weight portion, Radix Gentianae 10-20 weight portion, Massa Medicata Fermentata 10-20 weight portion and Fructus Jujubae 20-30 weight portion.
2. be according to claim 1ly used for the treatment of the dyspeptic medicine of pig, it is characterized in that, described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 22-26 weight portion, Rhizoma Atractylodis Macrocephalae 20-25 weight portion, Herba Carlinae biebersteinii 12-18 weight portion, peppery Jiang Zi 12-15 weight portion, the cured dry 16-20 weight portion of fiber crops, puckery pears 23-26 weight portion, husky Rhizoma Zingiberis Recens 13-20 weight portion, Flos Cleistocalycis Operculati 12-15 weight portion, Cortex Fraxini 14-20 weight portion, Herba desmodii microphylli 15-20 weight portion, Aloe 23-26 weight portion, Pericarpium Citri Reticulatae 20-25 weight portion, Fructus Hordei Germinatus 10-13 weight portion, Radix Gentianae 13-20 weight portion, Massa Medicata Fermentata 10-16 weight portion and Fructus Jujubae 20-27 weight portion.
3. be according to claim 1ly used for the treatment of the dyspeptic medicine of pig, it is characterized in that, described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 24 weight portion, the Rhizoma Atractylodis Macrocephalae 23 weight portion, Herba Carlinae biebersteinii 15 weight portion, peppery Jiang Zi 14 weight portion, fiber crops cured dry 17 weight portions, puckery pears 25 weight portion, husky Rhizoma Zingiberis Recens 16 weight portion, Flos Cleistocalycis Operculati 14 weight portion, Cortex Fraxini 17 weight portion, Herba desmodii microphylli 17 weight portion, Aloe 25 weight portion, Pericarpium Citri Reticulatae 23 weight portion, Fructus Hordei Germinatus 12 weight portion, Radix Gentianae 16 weight portion, Massa Medicata Fermentata 13 weight portion and Fructus Jujubae 24 weight portion.
4. be used for the treatment of the dyspeptic medicine of pig, it is characterized in that, described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 20-30 weight portion, Rhizoma Atractylodis Macrocephalae 20-30 weight portion, Herba Carlinae biebersteinii 10-20 weight portion, peppery Jiang Zi 10-15 weight portion, the cured dry 10-20 weight portion of fiber crops, puckery pears 20-30 weight portion, husky Rhizoma Zingiberis Recens 10-20 weight portion, Flos Cleistocalycis Operculati 10-15 weight portion, Cortex Fraxini 10-20 weight portion, Herba desmodii microphylli 10-20 weight portion, Aloe 20-30 weight portion, Pericarpium Citri Reticulatae 20-30 weight portion, Fructus Hordei Germinatus 10-15 weight portion, Radix Gentianae 10-20 weight portion, Massa Medicata Fermentata 10-20 weight portion, Fructus Jujubae 20-30 weight portion, cover Herba caryopteridis nepetaefoliae 10-20 weight portion, Endothelium Corneum Gigeriae Galli 10-20 weight portion, Radix Incarvilleae compactae 10-20 weight portion and Semen Aesculi 10-24 weight portion.
5. be according to claim 4ly used for the treatment of the dyspeptic medicine of pig, it is characterized in that, described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 22-26 weight portion, Rhizoma Atractylodis Macrocephalae 20-25 weight portion, Herba Carlinae biebersteinii 12-18 weight portion, peppery Jiang Zi 12-15 weight portion, the cured dry 16-20 weight portion of fiber crops, puckery pears 23-26 weight portion, husky Rhizoma Zingiberis Recens 13-20 weight portion, Flos Cleistocalycis Operculati 12-15 weight portion, Cortex Fraxini 14-20 weight portion, Herba desmodii microphylli 15-20 weight portion, Aloe 23-26 weight portion, Pericarpium Citri Reticulatae 20-25 weight portion, Fructus Hordei Germinatus 10-13 weight portion, Radix Gentianae 13-20 weight portion, Massa Medicata Fermentata 10-16 weight portion, Fructus Jujubae 20-27 weight portion, cover Herba caryopteridis nepetaefoliae 10-15 weight portion, Endothelium Corneum Gigeriae Galli 15-20 weight portion, Radix Incarvilleae compactae 10-15 weight portion and Semen Aesculi 15-20 weight portion.
6. be according to claim 4ly used for the treatment of the dyspeptic medicine of pig, it is characterized in that, described medicine is made up of the raw medicinal material of following parts by weight: Rhizoma Coptidis 24 weight portion, the Rhizoma Atractylodis Macrocephalae 23 weight portion, Herba Carlinae biebersteinii 15 weight portion, peppery Jiang Zi 14 weight portion, cured dry 17 weight portions of fiber crops, puckery pears 25 weight portion, husky Rhizoma Zingiberis Recens 16 weight portion, Flos Cleistocalycis Operculati 14 weight portion, Cortex Fraxini 17 weight portion, Herba desmodii microphylli 17 weight portion, Aloe 25 weight portion, Pericarpium Citri Reticulatae 23 weight portion, Fructus Hordei Germinatus 12 weight portion, Radix Gentianae 16 weight portion, Massa Medicata Fermentata 13 weight portion, Fructus Jujubae 24 weight portion, cover Herba caryopteridis nepetaefoliae 12 weight portion, Endothelium Corneum Gigeriae Galli 18 weight portion, Radix Incarvilleae compactae 13 weight portion and Semen Aesculi 18 weight portion.
7. the preparation method being used for the treatment of the dyspeptic medicine of pig as described in any one of claim 1-6, it is characterized in that, described preparation method comprises the following steps: take all raw medicinal materials according to ratio of weight and number, be ground into coarse powder, pulverize further again, cross 100 order ~ 120 mesh sieves, the fine powder amount that enable pass is sieved reaches 30%, collects and obtains fine powder a by the fine powder of sieve; Again the coarse powder not by 100 order ~ 120 mesh sieves is dropped into multi-function extractor to extract twice, first time adds coarse powder 5-10 times amount soak by water 1-2 hour, second time adds coarse powder 4-8 times amount soak by water 1-2 hour, merge twice decocting liquid, filter to get filtrate, heating is concentrated into pasty state, puts into after 80 DEG C, baking oven is dried and cools, grind to form fine powder b, fine powder a and fine powder b is mixed to get drug powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410040064.4A CN103751675B (en) | 2014-01-27 | 2014-01-27 | Be used for the treatment of dyspeptic medicine of pig and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410040064.4A CN103751675B (en) | 2014-01-27 | 2014-01-27 | Be used for the treatment of dyspeptic medicine of pig and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103751675A CN103751675A (en) | 2014-04-30 |
| CN103751675B true CN103751675B (en) | 2015-11-04 |
Family
ID=50519102
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410040064.4A Active CN103751675B (en) | 2014-01-27 | 2014-01-27 | Be used for the treatment of dyspeptic medicine of pig and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103751675B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1214248A (en) * | 1997-10-14 | 1999-04-21 | 高学剑 | Chinese medicine for digestive system diseases |
| CN1311012A (en) * | 2000-03-03 | 2001-09-05 | 郭岩红 | Preparing method for auxiliary feedback treatment of disease medicine |
| CN103316272A (en) * | 2012-03-21 | 2013-09-25 | 汕头市畜宝生物科技有限公司 | Chinese medicinal composition for preventing swine diarrhea |
-
2014
- 2014-01-27 CN CN201410040064.4A patent/CN103751675B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1214248A (en) * | 1997-10-14 | 1999-04-21 | 高学剑 | Chinese medicine for digestive system diseases |
| CN1311012A (en) * | 2000-03-03 | 2001-09-05 | 郭岩红 | Preparing method for auxiliary feedback treatment of disease medicine |
| CN103316272A (en) * | 2012-03-21 | 2013-09-25 | 汕头市畜宝生物科技有限公司 | Chinese medicinal composition for preventing swine diarrhea |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103751675A (en) | 2014-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102048933B (en) | Chinese medicinal composition for treating infantile diarrhea and preparation method thereof | |
| CN103734548B (en) | Feedstuff for treating swine dyspepsia and preparation method thereof | |
| CN105343625A (en) | Taraxacum oral liquid for expelling toxin, dehumidifying and benefiting gallbladder and preparation method thereof | |
| CN103690919B (en) | Medicine being used for the treatment of piglet iron-deficiency anemia and preparation method thereof | |
| CN103405728B (en) | A kind of Chinese medicine composition for the treatment of climacteric syndrome and preparation method thereof | |
| CN103432530B (en) | Traditional Chinese medicine composition for treating endometriosis and preparation method thereof | |
| CN101972338A (en) | Chinese medicinal preparation for treating infantile upper respiratory tract infection and preparation method thereof | |
| CN103719492A (en) | Gynostemma pentaphylla liver protecting and nourishing health-care tea and preparation method thereof | |
| CN102488848A (en) | Traditional Chinese medicine composition used for treating high-pathogenicity porcine reproductive and respiratory syndrome, preparation method thereof, and application thereof | |
| CN102205108A (en) | Traditional Chinese medicine preparation for treating gastric ulcer and preparation method thereof | |
| CN103719495B (en) | A kind of great burdock achene hypoglycemic health protection tea and preparation method thereof | |
| US10485834B2 (en) | Chinese herbal oral paste for conditioning phlegm-dampness constitution and processing method thereof | |
| CN104398991A (en) | Medicinal composition for treating hypogalactia symptom of dairy cow and preparation method thereof | |
| CN103041262B (en) | Traditional Chinese medicine enema for curing chronic prostatitis and preparing method thereof | |
| CN103431260A (en) | Mixed-grain full-nutrition formulation food for patients with gastrointestinal tract malabsorption and pancreatitis | |
| CN103705835B (en) | Medicine being used for the treatment of cad pig and preparation method thereof | |
| CN103751675B (en) | Be used for the treatment of dyspeptic medicine of pig and preparation method thereof | |
| CN102091262B (en) | Antidiarrheal powder | |
| CN105233078A (en) | Traditional Chinese medicine composition for treating viral hepatitis | |
| CN105106696A (en) | Traditional Chinese medicinal composition for treating chronic prostatitis | |
| CN104606538A (en) | Traditional Chinese medicine health product for preventing and treating diabetes | |
| CN103690771B (en) | Be used for the treatment of medicine of lamb colibacillosis and preparation method thereof | |
| CN103520643A (en) | Traditional Chinese medicine preparation used for treating diabetic cataract as well as preparation method of preparation | |
| CN108853380B (en) | Pharmaceutical composition for treating diabetes and preparation method and application thereof | |
| CN104645247A (en) | Traditional Chinese medicine preparation for treating hepatolenticular degeneration and preparation method of traditional Chinese medicine preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170930 Address after: Jinhua Town Lake District of Guizhou city of Guiyang province No. 998 550081 Patentee after: Guiyang new hope agricultural science and Technology Co., Ltd. Address before: 266061 Shandong city of Qingdao province Chengyang Jihongtan Street Green Industrial Park Patentee before: Shandong New Hope Liuhe Group Co., Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20171215 Address after: 266111 Shandong city of Qingdao province Chengyang Jihongtan Street Green Industrial Park Patentee after: Shandong New Hope Liuhe Group Co., Ltd. Address before: Jinhua Town Lake District of Guizhou city of Guiyang province No. 998 550081 Patentee before: Guiyang new hope agricultural science and Technology Co., Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20191106 Address after: 550018 No. 998, Jinhua Town, guanshanhu District, Guiyang City, Guizhou Province Patentee after: Guiyang new hope agricultural science and Technology Co., Ltd. Address before: 266111 Shandong city of Qingdao province Chengyang Jihongtan Street Green Industrial Park Patentee before: Shandong New Hope Liuhe Group Co., Ltd. |