CN103735715B - Compound donkey-hide gelatin preparation is preparing the application in resisting kinetic fatigue medicine - Google Patents
Compound donkey-hide gelatin preparation is preparing the application in resisting kinetic fatigue medicine Download PDFInfo
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- CN103735715B CN103735715B CN201310745709.XA CN201310745709A CN103735715B CN 103735715 B CN103735715 B CN 103735715B CN 201310745709 A CN201310745709 A CN 201310745709A CN 103735715 B CN103735715 B CN 103735715B
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Abstract
The object of the invention is to compound donkey-hide gelatin preparation and prepare the application in resisting kinetic fatigue medicine.Particularly this compound donkey-hide gelatin preparation improves the application in the medicine of application in the medicine of human body maximal oxygen uptake and compound donkey-hide gelatin preparation creatine kinase, blood urea nitrogen, cortisol levels during preparation reduces human motion in preparation.
Description
Technical field
The present invention relates to a kind of novelty teabag of known drug, exactly relate to a kind of novelty teabag of the herbal mixture containing Colla Corii Asini.
Background technology
The recovery of sports fatigue is the important topic of scientific research always.The traditional Chinese medicine of China has unique advantage in resisting fatigue.The increasing scholar Chinese medicine of selecting China traditional, develops the sports tonica containing various different Chinese medicinal ingredients, for eliminating the fatigue that large training produces in recent years.
FUFANG EJIAO JIANG is country's first batch of Chinese medicine protection kind, and it has effect of benefiting qi and nourishing blood, and what be mainly used in that QI and blood deficiency causes has a dizzy spell, palpitation and insomnia, inappetence, leukopenia and anemia.
FUFANG EJIAO JIANG is in the traditional Chinese medical science " damage person's benefit ", and under the principle guidance of " diseases caused by over-strain should be treated by warming " and " weak physique requiring qi-tonifying therapy, insufficiency of essence person tonifying with drugs of thick flavor ", using drugs to form a prescription forms.Prescription is with reference to recording side based on " two instrument cream " in the Ming Dynasty's famous physician's ZHANG Jie bin Jing-Yue Complete Works, " two instrument cream " is made up of Radix Codonopsis, Radix Rehmanniae Preparata, FUFANG EJIAO JIANG namely on this basis, adopts Colla Corii Asini to be equipped with Radix Ginseng (Radix Ginseng Rubra), Radix Codonopsis, Radix Rehmanniae Preparata and Fructus Crataegi composition.Colla Corii Asini primary efficacy is liver and kidney tonifying, and the raw marrow of replenishing essence is with YIN nourishing blood; Radix Ginseng is invigorating primordial QI; Radix Rehmanniae Preparata nourishing the liver and kidney, life essence-filling, marrow-benefitting; Radix Codonopsis invigorating the spleen and benefiting QI, assists hemopoietic QI invigorating; Fructus Crataegi circulation of qi promoting is whetted the appetite, strengthening the spleen to promote digestion.Sum up for: hemopoietic, QI invigorating, spleen invigorating, YIN nourishing, to help digestion.FUFANG EJIAO JIANG has the function of benefiting qi and nourishing blood.So far, in FUFANG EJIAO JIANG listing more than 30 years, indication is extensive, as long as dialectical is clinically that the patient of QI and blood deficiency is nearly all applicable.A large amount of clinical experimental study shows, Colla Corii Asini has promotion bone marrow hematogenesis, improves microcirculation, improves the effects such as immunity of organisms, regulating plant function of nervous system, anti peroxidation of lipid and slow down aging, and the scope of application is wide.
Summary of the invention
Compound donkey-hide gelatin preparation is the object of the present invention is to provide to prepare the application in resisting kinetic fatigue medicine.
Compound donkey-hide gelatin preparation is particularly provided to improve the application in the medicine of human body maximal oxygen uptake in preparation; And the application in the medicine of compound donkey-hide gelatin preparation creatine kinase, blood urea nitrogen, cortisol levels during preparation reduces human motion.
Compound donkey-hide gelatin preparation of the present invention comprises FUFANG EJIAO JIANG, is produced by Dong-E donkey-hide Gelatin Co., Ltd., Shandong Prov., the accurate word Z20083345 of traditional Chinese medicines, adopts Colla Corii Asini to be equipped with Radix Ginseng, Radix Codonopsis, Radix Rehmanniae Preparata and Fructus Crataegi composition.
Compound donkey-hide gelatin preparation instructions of taking of the present invention is:
Man: 3 times/day, 20 milliliters (normally) (1)-40 milliliters (high dose) (2), takes more than 4 weeks continuously;
Woman: 3 times/day, 20 milliliters of milliliter (1), menstrual phase is withdrawn, and takes more than 4 weeks continuously.
Detailed description of the invention
Further illustrate novelty teabag of the present invention by the following examples, but be not used for limiting the present invention.
Experimental example 1 FUFANG EJIAO JIANG improves the research of athlete's anti-fatigue ability
Research design: this project is included athlete in and related to the projects such as track and field, boxing, tae kwon do, table tennis.Experimenter's continuous oral 8 weeks medicines (the feminine menstrual phase withdraws), respectively at before taking medicine, take medicine after 4 weeks, 8 weeks test indices, the instructions of taking of high dose and normal dose and consumption?
Selected and exclusion standard: inclusion criteria: age 18-35 year; The athlete of the above grade of country's secondary; Signed Informed Consent Form, participates in this research voluntarily, can observe all test requirements documents.
Exclusion standard: accepted any other nutritional supplement in entering to organize first 4 weeks; Hemoglobin (Hb) > 160g/L; Erythrocyte (RBC) > 5.5 × 10
12/ L; Leukocyte (WBC) > 10.0 × 10
9/ L; Glutamic oxaloacetic transaminase, GOT (AST) > 50U/L; Glutamate pyruvate transaminase (ALT) > 40U/L; Just suffer from respiratory tract infection; Female urine pregnancy tests positive; There are FUFANG EJIAO JIANG allergies and normal diet allergies person; Researcher thinks the athlete being not suitable for this research.
Test index: following index is surveyed in choosing: 1) ordinary circumstance: body weight, blood pressure, pulse, Chen Mai, meal situation, drinking-water situation, sleep state, muscle power feel evaluation, couch to athlete's muscle power status evaluation, now health condition etc.2) lab index: routine blood test, ten, urine, hepatic and renal function, electrocardiogram and pulmonary function, fatigue index, hormone test, immunity test, oxidation resistance index etc.;
3) possible untoward reaction symptom, sign record: the primary part observation cardiopalmus relevant with medicine, uncomfortable in chest, breathe hard, gastric abscess, gastral cavity are swollen, abdominal distention, diarrhoea, Nausea and vomiting, xerostomia, epistaxis, anaphylaxis (as erythra) etc.4) data collection of motor capacity index: the training index that when training according to each specialized movement person, routine is examined or check carries out selectivity test before and after taking medicine, as back strength, grip, deep-knee-bend strength, sleeping thrust amount, peak power, 100m run (speed), 400m race (anaerobic endurance), anaerobic endurance (30 seconds anaerobic power), 3000m race (aerobic endurance), aerobic endurance (maximal oxygen uptake), specific strength, endurance for specialized training, subjective muscle power sensation grade hierarchical table (RPE), train the physical status evaluation of athlete.The athletic sports achievement of actual evaluation improves situation.
Statistical analysis: analyze for disparity items classified statistics.To taking medicine, front and back test index carries out statistical analysis.The take medicine mode of front and back own control of experimenter is adopted to carry out longitudinal comparison analysis.To number of subjects between identical items different group according to carrying out comparative analysis between transverse set.
Experimental result
This research first stage includes object of study 120 athletes (table tennis and each 60 people of tae kwon do) in, and wherein male sex worker 69 people, women's splendid dress 51 people, athlete's grade is more than national secondary.Arrange matched group and test group, test group is divided into again routine dose group and high dose group, and experimenter's nature situation is in table 1.
Table 1 object of study nature situation
Table 2 male sex worker test period White blood cell (109/L)
* represent to take medicine before 8 Zhou Houyu take medicine and compare, P<0.05; ▽ represents and to compare with between routine dose group, high dose group, P<0.05
Table 3 women's splendid dress test period White blood cell (109/L)
| Testing time | Matched group | Routine dose | High dose group |
| Before taking medicine | 5.1±0.4 | 5.1±0.8 | 5.8±0.7 |
| 2 weeks | 5.3±0.9 | 4.8±1.4 | 6.9±1.3 |
| 4 weeks | 5.6±1.3 | 5.2±0.9 | 5.9±1.1 |
| 8 weeks | 6.1±2.3 | 6.6±1.6* | 8.8±1.2* |
* represent to take medicine before 8 Zhou Houyu take medicine and compare, P<0.05; ▽ represents and to compare with matched group, routine dose group, P<0.05
The change of table 4 male sex worker test period erythrocyte, hemoglobin and oxygen carrying capacity
| Index | Testing time | Matched group | Routine dose | High dose group |
| Erythrocyte (10 12/L） | Before taking medicine | 4.2±0.6 | 4.3±0.4 | 4.2±0.4 |
| 2 weeks | 4.1±0.9 | 4.4±0.3 | 4.2±0.7 | |
| 4 weeks | 4.3±0.3 | 4.3±0.2 | 4.5±0.5 | |
| 8 weeks | 4.3±0.2 | 4.6±0.1 | 4.7±0.8* | |
| Hemoglobin (g/L) | Before taking medicine | 141.4±37.7 | 134.7±7.6 | 143.0±21.7 |
| 2 weeks | 145.6±12.1 | 146.7±5.1 | 153.7±8.5 | |
| 4 weeks | 150.9±11.4* | 150.8±8.7* | 159.0±11.5* | |
| 8 weeks | 150.3±10.0* | 159.3±8.7* | 165.6±14.4* | |
| Packed cell volume (%) | Before taking medicine | 41.8±9.6 | 42.5±7.3 | 40.5±6.5 |
| 2 weeks | 40.7±10.1 | 43.8±2.1 | 41.9±6.3 | |
| 4 weeks | 43.1±3.1 | 42.6±1.6 | 43.8±2.1 | |
| 8 weeks | 42.1±2.3 | 42.6±2.2 | 43.9±2.6* |
* represent compared with before taking medicine, P<0.05; ▽ represents and to compare with matched group, P<0.05
The change of table 5 women's splendid dress test period erythrocyte, hemoglobin
* represent with take medicine before compare, P<0.05, * *: P<0.01; ▽ represents and to compare with routine dose group, high dose group, P<0.05
Table 6 women's splendid dress exercise fatigue dependence test index
* represent with take medicine before compare, P<0.05; ☆ compares with other two groups when representing and take medicine 8 weeks, P<0.05
Table 7 male sex worker and exercise fatigue dependence test index
* represent with take medicine before compare, P<0.05; ☆ compares with other two groups when representing and take medicine 8 weeks, P<0.05
The change of table 8 women's splendid dress test period maximal oxygen uptake
* represent and take medicine 2 weeks and compare before taking medicine, P<0.05; △ represents and takes medicine 2 weeks and compare before taking medicine, P<0.05; ☆ represents and to compare with routine dose group and high dose group, P<0.05
The change of table 9 male sex worker test period maximal oxygen uptake
* represent with take medicine 2 weeks, take medicine before compare, P<0.05; *: P<0.01; ☆ represents and to compare with routine dose group and high dose group, P<0.05
Result shows: this research finds that taking FUFANG EJIAO JIANG continuously can significantly improve athlete's maximal oxygen uptake level, and then improves athletic aerobic sport ability; Take the level of creatine kinase during FUFANG EJIAO JIANG can reduce Athletes, blood urea nitrogen, hydrocortisone, illustrate that FUFANG EJIAO JIANG can alleviate training athlete phase degree of fatigue, find that this resisting fatigue effect is not remarkable in a short time, needs long-term taking just to take effect simultaneously; FUFANG EJIAO JIANG has positive effect in lifting erythrocyte and hemoglobin, also needs the regular hour to act on simultaneously.Male sex worker embodies certain significant difference in taking dose, but women's splendid dress does not show significant difference in taking dose.
Claims (1)
1. compound donkey-hide gelatin preparation improves the application in the medicine of human body maximal oxygen uptake in preparation; Described compound donkey-hide gelatin preparation is produced by Dong-E donkey-hide Gelatin Co., Ltd., Shandong Prov., the accurate word Z20083345 of traditional Chinese medicines, adopts Colla Corii Asini to be equipped with Radix Ginseng, Radix Codonopsis, Radix Rehmanniae Preparata and Fructus Crataegi and makes.
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| CN102895459A (en) * | 2012-09-10 | 2013-01-30 | 青岛广昭国际贸易有限公司 | Longevity-prolonging health-strengthening donkey-hide gelatin jelly |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102895459A (en) * | 2012-09-10 | 2013-01-30 | 青岛广昭国际贸易有限公司 | Longevity-prolonging health-strengthening donkey-hide gelatin jelly |
Non-Patent Citations (4)
| Title |
|---|
| 中医药防治运动性疲劳研究概况;黄美花;《广西中医药》;19980831;第21卷(第4期);第50-52页 * |
| 复方阿胶浆对小鼠抗疲劳作用的实验研究;练美莲;《中医中药》;20060731;第3卷(第21期);第115-116页 * |
| 复方阿胶浆对小鼠抗疲劳能力的影响;张路，等;《中国实验方剂学杂志》;20131031;第19卷(第19期);第254-257页 * |
| 阿胶补益作用机理新解及其临床应用;戴兴歧，等;《临沂医学专科学校学报》;20051231;第27卷(第5期);第331-332页 * |
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