CN103705676A - Traditional Chinese medicinal preparation for preventing and treating thromboangiitis obliterans - Google Patents

Traditional Chinese medicinal preparation for preventing and treating thromboangiitis obliterans Download PDF

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CN103705676A
CN103705676A CN201310727123.0A CN201310727123A CN103705676A CN 103705676 A CN103705676 A CN 103705676A CN 201310727123 A CN201310727123 A CN 201310727123A CN 103705676 A CN103705676 A CN 103705676A
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chinese medicinal
traditional chinese
chinese medicine
rhizoma
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CN103705676B (en
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郭伟基托夫
郭章发
郭香玉
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Chen Lihui
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TAICANG WEIJI BIOLOGICAL TECHNOLOGY Co Ltd
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Abstract

The invention provides a traditional Chinese medicinal preparation for preventing and treating thromboangiitis obliterans. The preparation preferably comprises the following components in parts by weight: 13 parts of zaocys dhumnade, 75 parts of astragalus membranaceus, 13 parts of Chinese angelica, 5 parts of red peony root, 8 parts of earthworm, 18 parts of centipede, 10 parts of ligusticum wallichii, 4 parts of safflower, 20 parts of pinellia ternata, 10 parts of codonopsis pilosula, and 18 parts of rhizoma typhonii. The traditional Chinese medicinal preparation is prepared in the following steps: screening the traditional Chinese medicinal materials, and crushing in a crusher to be 30 meshes; grinding the crushed traditional Chinese medicinal materials in a grinder to prepare traditional Chinese medicinal powder of 150 meshes; sterilizing the grinded traditional Chinese medicinal powder in vacuum, and filling into a bottle to obtain the traditional Chinese medicinal preparation for preventing and treating thromboangiitis obliterans. The traditional Chinese medicinal capsules are prepared by processing and extracting 13 traditional Chinese medicines, the effective components of the medicines can be maintained, and the capsules are easy to prepare and remarkable in curative effect.

Description

A kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans
Technical field
The invention belongs to technical field of Chinese medicines, specifically a kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans.
Background technology
Thromboangiitis obliterans betides the struvite vascular lesion of chronic progressive external segmental of middle small artery (simultaneously involving vein and nerve), and pathological changes is involved blood vessel holostrome, causes luminal stenosis, obturation.Claim again Buerger's disease, this sick multiple male adults of being born in, has severe to have a liking for cigarette history more.Thromboangiitis obliterans show as intermittent claudication, rest pain and migratory thrombophlebitis.This disease is mainly invaded limbs, especially lower limb in, vein and the skin superficial vein of small artery and companion's row thereof, involved vessels presents the nonsuppurative inflammation of blood vessel wall holostrome, in tube chamber, there is thrombosis, it is narrow so that entirely shut that tube chamber presents carrying out property, causing limb ischemia and produce pain, can there is to be difficult for ulcer and the gangrene of healing in severe patient acra.The cause of disease it be unclear that so far.May cause permanent disfunction or limbs to be lost, even dead.
Thromboangiitis obliterans is between twenty and fifty tremulous pulse and a kind of periodicity, the segmental inflammatory disorders of vein.Pathological changes majority occurs in limb vessel, and especially lower limb are common.First pathological change is vascellum tunica interna incrassation, has subsequently thrombosis, so that last blood vessel total blockage.Conventionally first pathological changes comes across limb artery far-end, as after shin, before shin, chi, oar, arch of foot, deep palmar arch, toe, the tremulous pulse such as refer to, pathological changes further develops just involves femoral artery and brachial artery etc.Boundary line between lesion segment and normal part is very clearly demarcated, and accompanying vein is often got involved simultaneously, generally all lighter, but late period, blood vessel had proliferation of fibrous tissue, sclerosis around.
Summary of the invention
The object of the invention is the defect existing for existing medicine in treatment, a kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans is provided.
Technical scheme of the present invention is achieved in that
Prevent and treat a Chinese medicine preparation for thromboangiitis obliterans, its Chinese medicine proportioning is by weight: Zaocys 12-15 part, Radix Astragali 60-80 part, Radix Angelicae Sinensis 10-15 part, Radix Paeoniae Rubra 3-8 part, Pheretima 5-10 part, Scolopendra 15-20 part, Rhizoma Chuanxiong 8-12 part, Flos Carthami 3-5 part, Rhizoma Pinelliae 15-25 part, Radix Codonopsis 8-12 part, Rhizoma Typhonii 15-20 part.
Prevent and treat a Chinese medicine preparation for thromboangiitis obliterans, its Chinese medicine optimum ratio is by weight: 13 parts of Zaocyss, 75 parts of the Radixs Astragali, 13 parts of Radix Angelicae Sinensis, 5 parts of Radix Paeoniae Rubra, 8 parts of Pheretimas, 18 parts of Scolopendras, 10 parts of Rhizoma Chuanxiongs, 4 parts, Flos Carthami, 20 parts of the Rhizoma Pinelliaes, 10 parts of Radix Codonopsis, 18 parts of Rhizoma Typhoniis.
A kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans of the present invention, the preparation technology of its medicine is: get after the advanced row filter of all taste Chinese medicinal materials of Zaocys, the Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Scolopendra, Rhizoma Chuanxiong, Flos Carthami, the Rhizoma Pinelliae, Radix Codonopsis, Rhizoma Typhonii and put it in pulverizer and pulverize, detailed catalogue is 30 orders, Chinese medicinal material after again these being pulverized drops into the grinding of grinding machine and makes Chinese medicinal powder, its detailed catalogue will be 150 orders, the Chinese medicine powder grinding to form will carry out vacreation and can be filled in bottle, is a kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans.
The returning through and act as of above-mentioned each Chinese medicine:
Zaocys: sweet, flat, return Liver Channel, have and dispel the wind, dredging collateral, relieving convulsion, can treat rheumatoid arthritis stubborn.Numbness contracture, hemiplegia, tic spasm, tetanus, leprosy, scabies etc.(Chinese Pharmacopoeia 2010 version one the 72nd page)
The Radix Astragali: sweet, temperature, returns lung, spleen channel, has invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, the effect of expelling pus and promoting granulation, can treat the deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts,
Burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, chronic nephritis proteinuria, diabetes etc.(Chinese Pharmacopoeia 2005 version one the 212nd page)
Radix Angelicae Sinensis: sweet, acrid, warm, return liver, the heart, spleen channel, having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation, can treat blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores etc.(Chinese Pharmacopoeia 2005 version one the 89th page)
Radix Paeoniae Rubra: hardship, be slightly cold, return Liver Channel.Have clearing away heat and cooling blood, the effect of eliminating stasis to stop pain, can treat maculae caused by violent heat pathogen. hematemesis and epistaxis, conjunctival congestion tumor, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, mass in the abdomen stomachache, injury from falling down. and carbuncle skin infection etc.(Chinese Pharmacopoeia 2005 version one the 109th page)
Pheretima: salty, cold, return liver, spleen, urinary bladder channel, there is heat clearing away arresting convulsion, dredging collateral, relievings asthma, and the effect of diuresis can be treated unconsciousness due to high fever, frightened sick tic, arthralgia, numb limbs and tense tendons, hemiplegia.Dyspnea and cough due to lung-heat, oliguria edema; Hypertension etc.(Chinese Pharmacopoeia 2005 version one the 80th page)
Scolopendra: pungent, temperature; Poisonous, return Liver Channel, there is endogenous wind stopping spasmolytic, dispersing pathogen accumulation, the effect of removing obstruction in the collateral to relieve pain, can treat infantile convulsion, tic spasm, drink in middle air port, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom etc.(Chinese Pharmacopoeia 2005 version one the 248th page)
Rhizoma Chuanxiong: pungent, temperature, returns liver, gallbladder, pericardium channel, has blood-activating and qi-promoting, the effect of wind-expelling pain-stopping, can treat the effect of menoxenia. and can control and treat mass in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache.Rheumatic arthralgia.(Chinese Pharmacopoeia 2005 version one the 28th page)
Flos Carthami: pungent, temperature, GUIXIN, Liver Channel, have promoting blood circulation to restore menstrual flow, and the effect of eliminating stasis to stop pain can be treated lochia , mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache etc.(Chinese Pharmacopoeia 2005 version one the 103rd page)
The Rhizoma Pinelliae: pungent, warm; Poisonous, return spleen, stomach, lung meridian, there is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass, can treat abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache, vomiting regurgitation, thymus painful abdominal mass is vexed, globus hystericus etc.(Chinese Pharmacopoeia 2005 version one the 78th page)
Radix Codonopsis: sweet, flat, return spleen, lung meridian, there is invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting, can treat deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst etc.(Chinese Pharmacopoeia 2005 version one the 199th page)
Rhizoma Typhonii: pungent, temperature; Poisonous, return stomach, Liver Channel, there is the expectorant of dispeling the wind, arresting convulsion is jerked, and the effect of detoxicating and resolving stagnation of pathogens pain relieving can be treated for wind-phlegm and be stopped up, and language is puckery stuttering, syncope due to accumulation of phlegm headache, migraine and general headache, sore throat pharyngalgia, tetanus; External treatment scrofula sucutaneous nodule, venom etc.(Chinese Pharmacopoeia 2005 version one the 70th page)
Implementation of an application example
Wang, man, 75 years old, the army's cadre that leaves one's post, private prosecution is when be on active service in borderland northeastward, and foot in winters two cold injury once increases the weight of when day cold, later local dull pain.Within 1988, start intermittent claudication, toes are blue, feel cold, pale, there is acra arteriospasm phenomenon, though through treatment for several times, symptom is aggravation gradually still, often night is unable to fall asleep, somewhere hospital plans to implement high-level amputation, patient is reluctant, through local intermediate court, checks: two lower limb muscles atrophys, and skin temperature obviously lowers, fine hair comes off, toenail thickening, pulsation of foot dorsal artery disappears, and posterior tibial artery and arteriopalmus also weaken, left foot the 2nd, 3,4 toe-ends fester, dense water is more, the swelling front instep of stretching, and around color of the leather is dark red.Left index finger can not be stretched in the wrong, and finger tip is mummification necrosis, and both sides radial artery pulse weakens, and makes a definite diagnosis: thromboangiitis obliterans (downright bad phase), through the traditional Chinese medical science, to treat in three stages 6 months, and the convergence of skin ulcer face is very large.Patient is leaving hospital behind walking 2 lis automatically through functional exercise in institute, but local dull pain appears again in patient after half a year, intermittent claudication symptom, then applies a kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans of the embodiment of the present invention two and takes two months, eliminate symptom, 2 years, had no recurrence more.
A kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans of the present invention, the medicine principle of its prescription is to take the Radix Astragali as group medicine, in large tonifying the spleen and stomach, gas, with the source of angry blood, makes the prosperous blood of gas, blood stasis dispelling and just not hindering.Radix Angelicae Sinensis is longer than and is invigorated blood circulation, and double can nourishing blood has blood stasis dispelling and non-blood trouble wonderful, is ministerial drug.Assistant, with Rhizoma Chuanxiong, Radix Paeoniae Rubra, Flos Carthami, helps Radix Angelicae Sinensis blood circulation promoting and blood stasis dispelling to take stopgap measures; Assistant Pheretima, with dredging collateral, coordinates with Radix Astragali, strengthens the power of invigorating qi and dredging collateral, makes all row whole bodies of efficacy of a drug energy.All medicines share, the prosperous blood of gas, and stagnation resolvation beniol, muscles is moistened foster, and the useless place of flaccidity can rehabilitation.
A kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans provided by the invention, its beneficial effect is: the Chinese medicine formula of this Chinese medicine preparation is reasonable, preparation technology is simple, easy to use, it is fast that preparation has curative effect, evident in efficacy, without toxicity, side effect.
The specific embodiment
Embodiment mono-
A kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans, its Chinese medicine proportioning is by weight: Zaocys 12-15 part, Radix Astragali 60-80 part, Radix Angelicae Sinensis 10-15 part, Radix Paeoniae Rubra 3-8 part, Pheretima 5-10 part, Scolopendra 15-20 part, Rhizoma Chuanxiong 8-12 part, Flos Carthami 3-5 part, Rhizoma Pinelliae 15-25 part, Radix Codonopsis 8-12 part, Rhizoma Typhonii 15-20 part, get Zaocys, the Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Scolopendra, Rhizoma Chuanxiong, Flos Carthami, the Rhizoma Pinelliae, Radix Codonopsis, after the advanced row filter of all taste Chinese medicinal materials of Rhizoma Typhonii, put it in pulverizer and pulverize, detailed catalogue is 30 orders, Chinese medicinal material after again these being pulverized drops into the grinding of grinding machine and makes Chinese medicinal powder, its detailed catalogue will be 150 orders, the Chinese medicine powder grinding to form will carry out vacreation and can be filled in bottle, for a kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans.
Embodiment bis-
A kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans, its Chinese medicine optimum ratio is by weight: 13 parts of Zaocyss, 75 parts of the Radixs Astragali, 13 parts of Radix Angelicae Sinensis, 5 parts of Radix Paeoniae Rubra, 8 parts of Pheretimas, 18 parts of Scolopendras, 10 parts of Rhizoma Chuanxiongs, 4 parts, Flos Carthami, 20 parts of the Rhizoma Pinelliaes, 10 parts of Radix Codonopsis, 18 parts of Rhizoma Typhoniis, get Zaocys, the Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Scolopendra, Rhizoma Chuanxiong, Flos Carthami, the Rhizoma Pinelliae, Radix Codonopsis, after the advanced row filter of all taste Chinese medicinal materials of Rhizoma Typhonii, put it in pulverizer and pulverize, detailed catalogue is 30 orders, Chinese medicinal material after again these being pulverized drops into the grinding of grinding machine and makes Chinese medicinal powder, its detailed catalogue will be 150 orders, the Chinese medicine powder grinding to form will carry out vacreation and can be filled in bottle, for a kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans.

Claims (2)

1. prevent and treat a Chinese medicine preparation for thromboangiitis obliterans, it is characterized in that Chinese medicine optimum ratio is by weight: 13 parts of Zaocyss, 75 parts of the Radixs Astragali, 13 parts of Radix Angelicae Sinensis, 5 parts of Radix Paeoniae Rubra, 8 parts of Pheretimas, 18 parts of Scolopendras, 10 parts of Rhizoma Chuanxiongs, 4 parts, Flos Carthami, 20 parts of the Rhizoma Pinelliaes, 10 parts of Radix Codonopsis, 18 parts of Rhizoma Typhoniis.
2. a kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans according to claim 1, the preparation technology who it is characterized in that Chinese medicine preparation is by the Zaocys of the claims in the present invention 1, the Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Scolopendra, Rhizoma Chuanxiong, Flos Carthami, the Rhizoma Pinelliae, Radix Codonopsis, after the advanced row filter of all taste Chinese medicinal materials of Rhizoma Typhonii, put it in pulverizer and pulverize, detailed catalogue is 30 orders, Chinese medicinal material after again these being pulverized drops into the grinding of grinding machine and makes Chinese medicinal powder, its detailed catalogue will be 150 orders, the Chinese medicine powder grinding to form will carry out vacreation and can be filled in bottle, for a kind of Chinese medicine preparation of preventing and treating thromboangiitis obliterans.
CN201310727123.0A 2013-12-19 2013-12-19 A kind of Chinese medicine preparation preventing and treating thromboangiitis obliterans Expired - Fee Related CN103705676B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105477277A (en) * 2016-01-28 2016-04-13 张红 Traditional Chinese medicine for treating thromboangiitis obliterans

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1334121A (en) * 2001-08-31 2002-02-06 石家庄以岭药业有限公司 Medicinal composition for restoring cardiac collaterals and its application
CN101468154A (en) * 2007-12-28 2009-07-01 牛海艳 Chinese medicine preparation for promoting blood circulation, activating collaterals of hemiplegia patient
CN101991780A (en) * 2009-08-13 2011-03-30 萧百川 Chinese material medical preparation for treating apoplexy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1334121A (en) * 2001-08-31 2002-02-06 石家庄以岭药业有限公司 Medicinal composition for restoring cardiac collaterals and its application
CN101468154A (en) * 2007-12-28 2009-07-01 牛海艳 Chinese medicine preparation for promoting blood circulation, activating collaterals of hemiplegia patient
CN101991780A (en) * 2009-08-13 2011-03-30 萧百川 Chinese material medical preparation for treating apoplexy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105477277A (en) * 2016-01-28 2016-04-13 张红 Traditional Chinese medicine for treating thromboangiitis obliterans

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Inventor after: Chen Lihui

Inventor before: Guo Weiji, Guo Zhangfa, Guo Xiangyu

Inventor before: Guo Zhangfa

Inventor before: Guo Xiangyu

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Effective date of registration: 20170823

Address after: 063000, 501, 5, 12, Guangming District, Fengrun Town, Fengrun District, Hebei, Tangshan City

Patentee after: Chen Lihui

Address before: 215400, Jiangsu, Chengxiang Town, Shanghai West Road, 29 (access) 607 room, Taicang Wei based Biotechnology Co., Ltd. Taicang

Patentee before: Taicang Weiji Biological Technology Co., Ltd.

CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20160420

Termination date: 20181219