CN102670910A - Traditional Chinese medicine formula for treating scleroderma - Google Patents

Traditional Chinese medicine formula for treating scleroderma Download PDF

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Publication number
CN102670910A
CN102670910A CN2012101363465A CN201210136346A CN102670910A CN 102670910 A CN102670910 A CN 102670910A CN 2012101363465 A CN2012101363465 A CN 2012101363465A CN 201210136346 A CN201210136346 A CN 201210136346A CN 102670910 A CN102670910 A CN 102670910A
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radix
weight
parts
chinese medicine
rhizoma
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CN2012101363465A
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谢培德
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Chengdu LVDI Technology Co Ltd
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Chengdu LVDI Technology Co Ltd
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Abstract

The invention provides a traditional Chinese medicine formula for treating scleroderma, which comprises 7 to 11 parts by weight of ligusticum chuanxiong, 7 to 11 parts by weight of peach kernels, 7 to 11 parts by weight of safflowers, 7 to 11 parts by weight of angelicas, 7 to 11 parts by weight of trogopterus dungs, 7 to 11 parts by weight of cyperus rotundus, 7 to 11 parts by weight of achyranthes bidentata, 7 to 11 parts by weight of gentiana macrophylla, 7 to 11 parts by weight of notopterygium roots, 9 to 15 parts by weight of earthworms, 12 to 18 parts by weight of suberect spatholobus stems, 28 to 32 parts by weight of astragalus, 7 to 11 parts by weight of rhubarbs and 7 to 11 parts by weight of cortex moutan. Compared with the prior art, the traditional Chinese medicine formula for treating the scleroderma distinguishes distinction to treat aiming at inner disease evil of the scleroderma, is rapid in curative effect and low in cost, does not have side effect, is obvious in effect, and treats both principal and secondary aspect of diseases.

Description

A kind of Chinese medicine preparation of treating scleroderma
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine preparation of treating scleroderma.
Background technology
Scleroderma is a kind of agnogenic autoimmune disease, and is pale or light red with hydroderma, the xerosis cutis that continues, smooth, thicken, hardening, attenuation, alopecia, finger tip and joint are prone to intractable ulcer etc. and are main clinical characteristics.The swelling phase is experienced in typical skin lesion successively, infiltration stage and atrophy phase three phases.Pathological changes is symmetry, and pathological changes is many by pointing gradually to proximal spread, and the boundary of affected skin and normal skin is unclear.Primary disease has the branch of limitation and systematicness, and the former is confined to skin and muscle damage, and in addition the latter still involves internal organs.The scleroderma age of onset to see 20~50 years old more, and the women is more than the male.Limitation person prognosis bona, systemic person, in case lung, the heart, kidney are got involved, the state of an illness worsens rapidly, prognosis is relatively poor.Scleroderma belongs to categories such as the traditional Chinese medical science " BI-syndrome involved the muscle ", " BI-syndrome related to skin ".For the treatment of scleroderma, doctor trained in Western medicine adopts vasoactive agent and connective tissue to form inhibitor for treating more, disease is had certain inhibitory action, but need life-time service, and side effect is more, and curative effect is very not remarkable again.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine preparation of treating scleroderma, it is to the inherent pathogenic factor of scleroderma, distinguishes that disease executing control, and with strong points, curative effect is fast, and cost is low, and has no side effect, and can reach to play good prevention effect.
In order to realize above-mentioned purpose, the present invention adopts following technical scheme: a kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: Rhizoma Chuanxiong 7-11, Semen Persicae 7-11; Flos Carthami 7-11, Radix Angelicae Sinensis 7-11, Oletum Trogopterori 7-11, Rhizoma Cyperi 7-11; Radix Achyranthis Bidentatae 7-11, Radix Gentianae Macrophyllae 7-11, Rhizoma Et Radix Notopterygii 7-11, Pheretima 9-15; Caulis Spatholobi 12-18, Radix Astragali 28-32, Radix Et Rhizoma Rhei 7-11, Cortex Moutan 7-11.
The Analysis on Mechanism of Chinese medicine of the present invention:
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping." herbal classic ": main apoplexy is gone into the brain headache, arthralgia due to cold, and the clonic spasm of the muscle emergency, the gold wound, married woman's blood closes loss of fecundity.
Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation." medication heart method ": Semen Persicae, bitter to let out stagnant blood, sweet with tissue regeneration promoting blood, so blood coagulation must be used.Heat in dehematizing again.
Flos Carthami: acrid in the mouth; Warm in nature.GUIXIN; The tripe warp.Invigorate blood circulation can through; Stasis-dispelling and pain-killing." book on Chinese herbal medicine just ": reach variola heat in blood difficulty and go out, the stasis of speckle rash does not disappear.
Radix Angelicae Sinensis: warm in nature, hide sweet, hot.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Materia Medica of Decoction: Radix Angelicae Sinensis, few the moon of starting with, with its heart master blood also; It is lunar to go into foot, wraps up in blood also with its spleen; Go into the sufficient the moon of fainting, also with its blood stored in the liver.
Oletum Trogopterori: bitter in the mouth; Sweet; Warm in nature.Return liver; Spleen channel.Promoting blood circulation and stopping pain; Removing stasis to stop bleeding; The removing food stagnancy detoxifcation.Cure mainly all pains of trusted subordinate's vim and vigour; Women's amenorrhea; The stasis of blood stagnated and suffered from abdominal pain puerperal; Metrostaxis." Bencao Jingshu ": Oletum Trogopterori, its merit is longer than the removing blood stasis promoting the circulation of blood, so stagnating, all blood stasis have a pain, puerperal blood faints, the stagnant blood centre of punch, few abdomen after-pains, the stagnant blood amenorrhea is had a pain between blood stasis heart stomach, the stasis passages through which vital energy circulates, gas must not be gone, and attacks cards such as thorn pain, must use in institute.
Rhizoma Cyperi: sweet in the mouth, be slightly cold, nontoxic.Go into liver, tri-jiao channel.The resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.Be used for stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, menoxenia, amenorrhea dysmenorrhea, colic of cold type stomachache, distending pain of the breast." the southern regions of the Yunnan Province book on Chinese herbal medicine ": transfer the gas in the blood, dissipating depression of QI, alleviating distention in middle-JIAO helps digestion, and preventing or arresting vomiting is told.
Radix Achyranthis Bidentatae: hardship; Acid; Property is put down.Return liver; Kidney channel.Invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; It is descending to ignite; Inducing diuresis for treating stranguria syndrome.Cure mainly soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis." Japan hanako materia medica ": control the waist knee joint soft timid cold a little less than, broken crux, the evacuation of pus pain relieving, puerperal cardiac and abdominal pain and blood fortune, the tire that falls, tonifying YANG.
Radix Gentianae Macrophyllae: hardship; Hot; Be slightly cold.Return stomach; Liver; Gallbladder meridian.Wind-damp dispelling; The Shujin network; Clearind deficient heat; The dampness removing jaundice eliminating.Cure mainly the logical pain of rheumatism numbness; The muscles and bones contracture; Hands and feet caused by paralysis.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature, return bladder, liver, kidney channel.Diffusing exterior cold; Wind-damp dispelling; Sharp joint; Pain relieving.Compendium of Material Medica: after the Qiang, Radix Angelicae Pubescentis, all can pursue wind prevailing over dampness, pass through Guan Lijie, but gas have firm bad different you.
Pheretima: its salty in the mouth, cold in nature.Return liver, spleen, urinary bladder channel.Dredge the meridian passage, blood circulation promoting and blood stasis dispelling.Cure mainly arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.Supplementary Amplifications of the Compendium of Materia Medica: invigorate blood circulation warm waist knee joint, paralysis.
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.The effect that invigorating QI to consolidate the body surface resistance, hidroschesis detoxification, granulation promoting, diuresis, detumescent are arranged.Give birth to consolidating superficial resistance holder skin ulcer.
Radix Et Rhizoma Rhei: hardship, cold.Return through the stomach warp; Large intestine channel; Liver Channel; Spleen channel.Attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Detoxifcation." Japan hanako materia medica ": logical all gas of a surname, blood circulation regulating, sharp joint is let out and is moulded stagnant, aqueous vapor, the extremity unbalanced cold and heat, warm miasma heat-phlegm, sharp defecation, and apply all furuncle carbuncle poison.
Cortex Moutan: cold in nature, bitter in the mouth; Cool; Be slightly cold.GUIXIN, liver, kidney, lung meridian.Bitter cold among the clearing away heat and cooling blood, is good at the dissipating blood stasis eliminating carbuncle.It is flourishing to control fire-toxin, carbuncle sore tumefacting virus.
To the scleroderma due to the stagnation of QI blood stasis, the traditional Chinese medical science is thought gas master blood, and circulation of qi promoting is strongly fragrant, blood stasis then, and the resistance of the flesh network stasis of blood is lost in scholar and is supported, and it is dark then to meet color, and skin is become thin, and the skin plate is hard; The gas active, depression and stagnation of QI, the dysphagia of then dehiscing; Purplish tongue is dim, thin fur, and thready and stringy pulse is levying of stagnation of QI blood stasis.
The person of choosing in the side, vital energy regualting and blood circulation-promoting, disperse blood stasis and dredge collateral, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Oletum Trogopterori are enriched blood and are invigorated blood circulation; Activating QI to alleviate the depression, the Rhizoma Cyperi resolving depression of regulating the flow of vital energy, the Radix Achyranthis Bidentatae promoting blood circulation to restore menstrual flow; The Radix Gentianae Macrophyllae easypro network that dispels the wind, notopterygium wind dispelling collateral dredging, Pheretima dredge the meridian passage; Caulis Spatholobi, Radix Astragali benefiting QI and nourishing blood, Radix Et Rhizoma Rhei, Cortex Moutan dissipating blood stasis and clearing away heat.To scleroderma determined curative effect due to the stagnation of QI blood stasis, prevention effect is remarkable, doublely takes stopgap measures this.
Form of Chinese drug of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
To the Chinese medicine of 30 scleroderma patients (age 35-50) use treatment scleroderma of the present invention, 1 course of treatment of continued treatment (2 months), wherein 11 examples are cured fully; 16 routine remissions; Invalid 3 examples, overall effective percentage reaches 90%, and does not have recurrence.
Instance:
The patient 1: week certain, the women, 47 years old, that skin of face becomes was tight, thicken, fine hair comes off, point swollen firmly, articulations digitorum manus pain.Take Chinese medicine of the present invention after one month, remission, continued was taken medicine to 1 course of treatment, and transference cure does not have recurrence so far half a year.
The patient 2: Feng, and the male, 35 years old, the back of the hand pallor, finger is sausage appearance, and to the near-end development, the back of the hand swelling has expansion trend, the trend that symptom does not alleviate after 1 month, and focus skin begins to thicken, and hardening is followed the string.Be diagnosed as scleroderma, take Chinese medicine of the present invention after 1 course of treatment, above-mentioned symptom all disappears, and does not see outbreak in 3 months so far.
The patient 3: thunder, and the women, 40 years old, Raynaud phenomenon appearred before 2 months, and finger skin was pale when disease was sent out, and numbness, prickling sensation are arranged, and then became stasis of blood green grass or young crops, flushing.Ulcer appears in finger after 1 month.And articulations digitorum manus is ached.Be diagnosed as scleroderma, the back uses Chinese medicine of the present invention to treat, and after half course of treatment, above-mentioned symptom is eased, and arthralgia alleviates, and the remission of ulcer skin lesion continued to take medicine to 1 course of treatment, and above-mentioned symptom all disappears, and does not have recurrence so far.
The specific embodiment
In order to understand the present invention better, through embodiment the present invention is described below.
Embodiment 1
A kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: Rhizoma Chuanxiong 7, Semen Persicae 7, Flos Carthami 7, Radix Angelicae Sinensis 7, Oletum Trogopterori 7, Rhizoma Cyperi 7, Radix Achyranthis Bidentatae 7, Radix Gentianae Macrophyllae 7, Rhizoma Et Radix Notopterygii 7, Pheretima 9, Caulis Spatholobi 12, the Radix Astragali 28, Radix Et Rhizoma Rhei 7, Cortex Moutan 7.
Its preparation method is:
In weight portion, get Rhizoma Chuanxiong 7, Semen Persicae 7, Flos Carthami 7, Radix Angelicae Sinensis 7, Oletum Trogopterori 7, Rhizoma Cyperi 7, Radix Achyranthis Bidentatae 7, Radix Gentianae Macrophyllae 7, Rhizoma Et Radix Notopterygii 7, Pheretima 9, Caulis Spatholobi 12, the Radix Astragali 28, Radix Et Rhizoma Rhei 7, Cortex Moutan 7; Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag.
Embodiment 2
A kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: Rhizoma Chuanxiong 11, Semen Persicae 11, Flos Carthami 11, Radix Angelicae Sinensis 11, Oletum Trogopterori 11, Rhizoma Cyperi 11, Radix Achyranthis Bidentatae 11, Radix Gentianae Macrophyllae 11, Rhizoma Et Radix Notopterygii 11, Pheretima 15, Caulis Spatholobi 18, the Radix Astragali 32, Radix Et Rhizoma Rhei 11, Cortex Moutan 11.
Its preparation method is:
In weight portion, get Rhizoma Chuanxiong 11, Semen Persicae 11, Flos Carthami 11, Radix Angelicae Sinensis 11, Oletum Trogopterori 11, Rhizoma Cyperi 11, Radix Achyranthis Bidentatae 11, Radix Gentianae Macrophyllae 11, Rhizoma Et Radix Notopterygii 11, Pheretima 15, Caulis Spatholobi 18, the Radix Astragali 32, Radix Et Rhizoma Rhei 11, Cortex Moutan 11; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
A kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: Rhizoma Chuanxiong 9, Semen Persicae 9, Flos Carthami 9, Radix Angelicae Sinensis 9, Oletum Trogopterori 9, Rhizoma Cyperi 9, Radix Achyranthis Bidentatae 9, Radix Gentianae Macrophyllae 9, Rhizoma Et Radix Notopterygii 9, Pheretima 12, Caulis Spatholobi 15, the Radix Astragali 30, Radix Et Rhizoma Rhei 9, Cortex Moutan 9.
Its preparation method is:
In weight portion, get Rhizoma Chuanxiong 9, Semen Persicae 9, Flos Carthami 9, Radix Angelicae Sinensis 9, Oletum Trogopterori 9, Rhizoma Cyperi 9, Radix Achyranthis Bidentatae 9, Radix Gentianae Macrophyllae 9, Rhizoma Et Radix Notopterygii 9, Pheretima 12, Caulis Spatholobi 15, the Radix Astragali 30, Radix Et Rhizoma Rhei 9, Cortex Moutan 9; Cleaning, drying mix above-mentioned medical material, use pulverizer to pulverize and are 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing promptly gets pill.
Embodiment 4
A kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: Rhizoma Chuanxiong 9, Semen Persicae 9, Flos Carthami 9, Radix Angelicae Sinensis 9, Oletum Trogopterori 9, Rhizoma Cyperi 9, Radix Achyranthis Bidentatae 9, Radix Gentianae Macrophyllae 9, Rhizoma Et Radix Notopterygii 9, Pheretima 12, Caulis Spatholobi 15, the Radix Astragali 30, Radix Et Rhizoma Rhei 9, Cortex Moutan 9.
Its preparation method is:
In weight portion, get Rhizoma Chuanxiong 9, Semen Persicae 9, Flos Carthami 9, Radix Angelicae Sinensis 9, Oletum Trogopterori 9, Rhizoma Cyperi 9, Radix Achyranthis Bidentatae 9, Radix Gentianae Macrophyllae 9, Rhizoma Et Radix Notopterygii 9, Pheretima 12, Caulis Spatholobi 15, the Radix Astragali 30, Radix Et Rhizoma Rhei 9, Cortex Moutan 9; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Granule is processed the 0.4g/ capsules with the capsule filler.

Claims (4)

1. a Chinese medicine preparation of treating scleroderma is characterized in that, in weight portion, comprises following component: Rhizoma Chuanxiong 7-11, Semen Persicae 7-11; Flos Carthami 7-11, Radix Angelicae Sinensis 7-11, Oletum Trogopterori 7-11, Rhizoma Cyperi 7-11; Radix Achyranthis Bidentatae 7-11, Radix Gentianae Macrophyllae 7-11, Rhizoma Et Radix Notopterygii 7-11, Pheretima 9-15; Caulis Spatholobi 12-18, Radix Astragali 28-32, Radix Et Rhizoma Rhei 7-11, Cortex Moutan 7-11.
2. Chinese medicine preparation according to claim 1 is characterized in that, in weight portion, preferably comprises following component: Rhizoma Chuanxiong 9, Semen Persicae 9, Flos Carthami 9; Radix Angelicae Sinensis 9, Oletum Trogopterori 9, Rhizoma Cyperi 9, Radix Achyranthis Bidentatae 9, Radix Gentianae Macrophyllae 9, Rhizoma Et Radix Notopterygii 9; Pheretima 12, Caulis Spatholobi 15, the Radix Astragali 30, Radix Et Rhizoma Rhei 9, Cortex Moutan 9.
3. Chinese medicine preparation according to claim 1 is characterized in that, said Chinese medicine preparation adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine preparation according to claim 1 is characterized in that said Chinese medicine preparation preferably adopts solution, granule, pill and capsule.
CN2012101363465A 2012-05-04 2012-05-04 Traditional Chinese medicine formula for treating scleroderma Pending CN102670910A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104208165A (en) * 2014-08-29 2014-12-17 王刚 Traditional Chinese medicine ointment for treating rhagades of hands and feet
CN104958495A (en) * 2015-07-29 2015-10-07 青岛蓝盛洋医药生物科技有限责任公司 Traditional Chinese medicine preparation for treating scleroderma and preparation method of traditional Chinese medicine preparation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1843421A (en) * 2005-04-07 2006-10-11 刘叙光 Rheumatoid disease treating medicine
CN101433609A (en) * 2008-12-03 2009-05-20 咸阳步长医药科技发展有限公司 Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases
CN102078467A (en) * 2009-12-01 2011-06-01 宋文静 Chinese medicine decoction for treating arthralgia
CN102247585A (en) * 2010-05-20 2011-11-23 潘治宇 Chinese medicinal composition for treating rheumatism, preparation thereof and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1843421A (en) * 2005-04-07 2006-10-11 刘叙光 Rheumatoid disease treating medicine
CN101433609A (en) * 2008-12-03 2009-05-20 咸阳步长医药科技发展有限公司 Use of pharmaceutical composition in preparing medicament for preventing and treating allergic diseases
CN102078467A (en) * 2009-12-01 2011-06-01 宋文静 Chinese medicine decoction for treating arthralgia
CN102247585A (en) * 2010-05-20 2011-11-23 潘治宇 Chinese medicinal composition for treating rheumatism, preparation thereof and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104208165A (en) * 2014-08-29 2014-12-17 王刚 Traditional Chinese medicine ointment for treating rhagades of hands and feet
CN104208165B (en) * 2014-08-29 2016-07-06 王刚 The traditional Chinese herb medicine for the treatment of rhagadia manus et pedis
CN104958495A (en) * 2015-07-29 2015-10-07 青岛蓝盛洋医药生物科技有限责任公司 Traditional Chinese medicine preparation for treating scleroderma and preparation method of traditional Chinese medicine preparation

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Application publication date: 20120919