CN103656294B - Medicine for treating acute glomerulonephritis and preparation method thereof - Google Patents
Medicine for treating acute glomerulonephritis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating acute glomerulonephritis and a preparation method thereof. The medicine is mainly prepared from fructus rosae laevigatae, oldenlandia, wrinkled giant hyssop, pomegranate bark, senstive plant root, motherwort, areca peel, common cephalanoplos herb, flos sophorae and the like in a certain weight ratio. The medicine has the functions of clearing heat and removing toxicity, and inducing diuresis and reducing edema, and is quick in response and high in cure rate when used for treating acute glomerulonephritis.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of acute glomerulonephritis of baby and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Acute glomerulonephritis of baby is often referred to acute poststreptococcal glomerulonephritis, by after A group β hemolytic streptococcal infection, exudative in the diffusivity glomerular capillary that caused immune complex deposit causes at glomerule, proliferative inflammation pathological changes.Clinical manifestation weight differs, and typical performance is edema, oliguria, hypertension.(acute glomerulonephritis is often referred to as acute nephritis.Broadly mean that one group of cause of disease and pathogeny differ, but clinical manifestation is Acute onset, drops to a class renal glomerular disease of feature with hematuria, edema, oliguria, hypertension and glomerular filtration rate, therefore be also often called acute nephritic syndrome.Most genus acute poststreptococcal glomerulonephritis on Pediatric Clinic.Primary disease can betide any age, is modal a kind of kidney disease in children's's period.In the majority with 3 ~ 8 years old, M-F is about 2: 1.Majority has Hemolytic streptococcus forerunner to infect history.) effectively cannot treat acute glomerulonephritis of baby due to Western medicine, and take Western medicine and have more side effect, costly, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment acute glomerulonephritis of baby, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment acute glomerulonephritis of baby, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment acute glomerulonephritis of baby.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Fructus Rosae Laevigatae, Herba Hedyotidis Diffusae, Herba Pogostemonis, Pericarpium Granati, Radix Mimosae Pudicae, Herba Leonuri, Pericarpium Arecae, Herba Cirsii, Flos Sophorae, Fructus Jujubae, Semen Armeniacae Amarum, Concha Ostreae, Herba Rostellulariae, Cortex Acanthopancis, Folium et Ramulus Clerodendri Trichotomi, Herba Artemisiae Anomalae, Herba Spirodelae, Spina Gleditsiae, Stigma Maydis, Herba Pyrolae, Herba Verbenae, Periostracum Cicadae, Cordyceps, Folium Isatidis, Herba Dianthi, Calyx Seu Fructus Physalis, Radix Pseudostellariae, Herba Menthae, Cortex Mori, Herba Eupatorii, Spora Lygodii medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat acute glomerulonephritis of baby.Fructus Rosae Laevigatae is selected to be that flat, have reinforcing the kidney and controlling nocturnal emission, the function of reducing urination and antidiarrheal, controls spermatorrhea, the enuresis, frequent micturition, insufficiency of the spleen dysentery because its nature and flavor are sour and astringent.Select Herba Hedyotidis Diffusae to be because its property bitter but sweet flavor, cold, enter the heart, liver, spleen three warp, have heat clearing away, dampness removing, the function of removing toxic substances, controls dyspnea and cough due to lung-heat, tonsillitis, pharyngolaryngitis, appendicitis, dysentery, jaundice, pelvic inflammatory disease, adnexitis, carbuncle furuncle, venom.Herba Pogostemonis is selected to be that tepor, enters lung, spleen, stomach warp, have fast gas because its nature and flavor are pungent, and in, ward off dirty, the function of damp eliminating, cure cold heat-damp in summer, cold and heat, and headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.Select Pericarpium Granati to be because its nature and flavor are sour and astringent, temperature, poisonous, enter large intestine, kidney channel, have astringing intestine to stop diarrhea, hemostasis, the function of anthelmintic, controls chronic diarrhea, and chronic dysentery is had blood in stool, proctoptosis, spermatorrhea, metrorrhagia, leukorrhagia, abdominal pain due to worm stagnation, scabies.Select Radix Mimosae Pudicae to be due to the puckery micro-hardship of its nature and flavor, temperature, poisonous, have relieving cough and resolving phlegm, dampness removing dredging collateral, stomach function regulating, the function of removing food stagnancy, controls chronic bronchitis, rheumatalgia, chronic gastritis, infantile dyspepsia.Select Herba Leonuri to be that cool, enter pericardium, Liver Channel, invigorate blood circulation, blood stasis dispelling, regulating menstruation, the function of the water that disappears, controls menoxenia because its nature and flavor are worked hard, control and Lou have difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Pericarpium Arecae is selected to be that tepor, enters spleen, stomach, intestine and small intestine warp, have therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, the function of row water, controls gastral cavity abdomen painful abdominal mass swollen, beriberi, edema because its nature and flavor are pungent.Select Herba Cirsii to be because its nature and flavor are pungent, temperature, enter spleen, stomach two warp, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, rapid digestion of food, the function of parasite killing, controls vomiting and diarrhoea, trusted subordinate's distending pain, furuncle toxic swelling skin ulcer, and poisonous insect flood dragon hinders.Flos Sophorae is selected to be that cool, enter liver, large intestine channel, have heat clearing away, removing heat from blood, the function of hemostasis, controls discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, epistaxis because its nature and flavor are bitter, under dysentery with red and white feces, wind heat conjunctival congestion, skin sore, and for prevention of stroke.Select Fructus Jujubae to be that temperature, enters spleen, stomach warp, have spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid because its nature and flavor are sweet, adjust battalion to defend, separate the function of poison of drug, control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Semen Armeniacae Amarum is selected to be that temperature, poisonous, enter lung, large intestine channel, have expelling phlegm for arresting cough, relieving asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation because its nature and flavor are bitter.Select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduce phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Herba Rostellulariae is selected to be that cold, enter liver, gallbladder two warp, have heat-clearing and toxic substances removing, dampness removing disappears stagnant, the function of promoting blood circulation and stopping pain, and cure cold heating because its nature and flavor are salty pungent, cough, laryngalgia, malaria, jaundice, nephritis edema, bones and muscles pain, infantile malnutrition, carbuncle furuncle, traumatic injury.Select Cortex Acanthopancis to be because its nature and flavor are pungent, temperature, enter liver, kidney channel, have wind-damp dispelling, strengthening bone and muscle, the function of blood circulation and promoting silt, controls anemofrigid-damp arthralgia, and muscles and bones contraction is anxious, lumbago, sexual impotence, flaccidity of the lower limbs, children's's walking retardation in children, edema, beriberi, skin ulcer cellulitis toxic swelling, traumatic injury impairment caused by overstrain.Select Folium et Ramulus Clerodendri Trichotomi to be because its nature and flavor hardship band is sweet, have wind-damp dispelling, the function of blood pressure lowering, dispelling the wind and dampness pathogens arthralgia pain, hemiplegia, hypertension, migraine, malaria, dysentery, hemorrhoid, carbuncle skin ulcer scabies.Select Herba Artemisiae Anomalae to be because its nature and flavor are bitter, temperature, enter the heart, spleen channel, have removing blood stasis to stimulate the menstrual flow, the function of healing up sore and subduing swelling, controls amenorrhea and mass in the abdomen, chest and abdomen swelling and pain, puerperal blood stasis, traumatic injury, incised wound is hemorrhage, Yong Du burning swelling.Select Herba Spirodelae to be because its nature and flavor are pungent, cold, enter lung meridian, have diaphoresis, dispel the wind, row water, heat clearing away, the function of removing toxic substances, row calentura when controlling, macule is not saturating, wind heat urticaria, skin pruritus, edema, the difficulty in urination, skin ulcer tinea, and erysipelas is scalded.Select Spina Gleditsiae to be that temperature, searches wind, draw out pus by applying a plaster to the affected part because its nature and flavor are pungent, detumescence, the function of evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.Stigma Maydis is selected to be that flat, have diuresis, expel the heat-evil, suppressing the hyperactive liver, the function of function of gallbladder promoting, controls oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, cholelithiasis, diabetes, hematemesis and epistaxis, nasal sinusitis, acute mastitis because its nature and flavor are sweet.Select Herba Pyrolae to be because its nature and flavor sweetness and bitterness, temperature, enters liver, kidney two warp, has tonify deficiency, kidney tonifying, expelling wind and removing dampness, the function of promoting blood flow to regulate menstruation, controls weak cough, over-strained hemoptysis, rheumatic arthritis, metrorrhagia, leucorrhea, traumatic hemorrhage.Herba Verbenae is selected to be that cool, enter liver, spleen channel, have heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, the function of inducing diuresis to remove edema, controls fever caused by exogenous pathogens, jaundice due to damp-heat, edema, dysentery, malaria, diphtheria, sore throat, gonorrhea, amenorrhea ， mass in the abdomen, carbuncle sore tumefacting virus ulcerative gingivitis because its nature and flavor are bitter.Select Periostracum Cicadae to be because its property sweet-salty, cool, enter lung, Liver Channel, have loose wind heat, lung qi dispersing, determine the function of convulsion, control affection due to external wind and heat, cough hoarseness, measles is sent out not smooth thoroughly, and rubella pruritus, little youngster shies Epilepsy, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.Select Cordyceps to be that temperature, enters lung, kidney two warp, have tonifying deficiency, the function of beneficial vital essence because its nature and flavor are sweet, control phlegm retention and breathe heavily and cough, dyspnea due to deficiency, consumptive disease is coughed, spitting of blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint, and prolonged deficiency is multiple after being ill.Folium Isatidis is selected to be because its nature and flavor are bitter, cold, enter liver, the heart, stomach warp, have heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis, controls epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spits blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Herba Dianthi is selected to be that cold, enter the heart, kidney, small intestinal, urinary bladder channel, have clearing away heat and promoting diuresis, the function that removing blood stasis stimulates the menstrual flow, control urinary obstruction, gonorrhea, edema, amenorrhea, carbuncle, conjunctival congestion is hidden from view because its nature and flavor are bitter, contamination sore.Calyx Seu Fructus Physalis is selected to be because its nature and flavor are bitter, cold, return Liver Channel, have heat-clearing and toxic substances removing, sore-throat relieving, reduce phlegm, the function of diuresis, control pharyngalgia hoarseness, phlegm-heat cough, dysuria, external treatment pemphigus, eczema.Radix Pseudostellariae is selected to be that tepor, enters the heart, spleen, lung three warp, have the function of tonifying the lung, spleen invigorating, control cough due to deficiency of the lung, insufficiency of the spleen lack of appetite, cardiopalmus order antiperspirant, metal fatigue because its nature and flavor sweetness and bitterness.Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, ward off dirty, the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Select Cortex Mori to be that cold, enter lung, spleen channel, have eliminating pathogen from the lung for relieving asthma, the function of line water detumescence, controls dyspnea and cough due to lung-heat because its nature and flavor are sweet, spit blood, edema, beriberi, dysuria.Select Herba Eupatorii to be that flat, enter spleen, stomach warp, have clearing away summer-heat, ward off dirty, removing dampness, the function of regulating menstruation, controls and experience heat-damp in summer because its nature and flavor are pungent, cold and heat are had a headache, and accumulate in damp, gastral cavity painful abdominal mass is not hungry, sweet taste in the mouth greasy fur, menoxenia.Select Spora Lygodii to be because its property slightly sweet flavor, cold, enter small intestinal, urinary bladder channel, have heat-clearing and toxic substances removing, the function of relieving stranguria by diuresis, controls urinary tract infection, lithangiuria, nebulousurine, leucorrhea, hepatitis, oedema due to nephritis, laryngopharynx swelling and pain, mumps, enteritis, dysentery, skin eczema, herpes zoster.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
Fructus Rosae Laevigatae 10-20 gram of Herba Hedyotidis Diffusae 5-15 gram of Herba Pogostemonis 6-16 gram
Pericarpium Granati 8-16 gram of Radix Mimosae Pudicae 10-18 gram of Herba Leonuri 8-20 gram
Pericarpium Arecae 8-15 gram of Herba Cirsii 6-15 gram of Flos Sophorae 8-16 gram
Fructus Jujubae 6-15 gram of Semen Armeniacae Amarum 8-15 gram of Concha Ostreae 5-15 gram
Herba Rostellulariae 5-12 gram of Cortex Acanthopancis 5-10 gram of Folium et Ramulus Clerodendri Trichotomi 5-18 gram
Herba Artemisiae Anomalae 8-16 gram of Herba Spirodelae 10-20 gram of Spina Gleditsiae 6-15 gram
Stigma Maydis 8-18 gram of Herba Pyrolae 6-16 gram of Herba Verbenae 10-20 gram
Periostracum Cicadae 3-8 gram of Cordyceps 5-10 gram of Folium Isatidis 10-20 gram
Herba Dianthi 6-15 gram of Calyx Seu Fructus Physalis 5-12 gram of Radix Pseudostellariae 4-8 gram
Herba Menthae 6-15 gram of Cortex Mori 5-15 gram of Herba Eupatorii 5-12 gram
Spora Lygodii 6-15 gram
Be preferably
Fructus Rosae Laevigatae 12 grams of Herba Hedyotidis Diffusaes 8 grams of Herba Pogostemoniss 8 grams
Pericarpium Granati 10 grams of Radix Mimosae Pudicaes 12 grams of Herba Leonuris 10 grams
10 grams, Pericarpium Arecae 10 grams of Herba Cirsiis 9 grams of Flos Sophoraes
Fructus Jujubae 8 grams of Semen Armeniacae Amarums 10 grams of Concha Ostreaes 8 grams
Herba Rostellulariae 8 grams of Cortex Acanthopanciss 6 grams of Folium et Ramulus Clerodendri Trichotomis 6 grams
Herba Artemisiae Anomalae 9 grams of Herba Spirodelaes 12 grams of Spina Gleditsiaes 8 grams
Stigma Maydis 10 grams of Herba Pyrolaes 8 grams of Herba Verbenae 10 grams
Periostracum Cicadae 5 grams of Cordyceps 8 grams of Folium Isatidiss 12 grams
Herba Dianthi 8 grams of Calyx Seu Fructus Physaliss 6 grams of Radix Pseudostellariaes 5 grams
Herba Menthae 8 grams of Cortex Mori 6 grams of Herba Eupatoriis 8 grams
Spora Lygodii 8 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Fructus Rosae Laevigatae: pick decontamination, cuts two lobes, slightly soaks with water, pull out, and after moistening, the residual burr of removing, digs clean hair, core, dry;
2, Herba Hedyotidis Diffusae: get crude drug, removing impurity, wash quickly is clean, slightly dries in the air, cutting, dry, sieve dedust bits;
3, Herba Pogostemonis: pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;
4, Pericarpium Granati: pick decontamination, removes residual interior flesh and son, and clean, stripping and slicing, dries;
5, Radix Mimosae Pudicae: summer, autumn gather, and clean, dry;
6, Herba Leonuri: pick decontamination, cleans, runs through, cutting, dry;
7, Pericarpium Arecae: pick clean impurity, rolloff makes soft, beats, sieve removes spare;
8, Herba Cirsii: pick clean impurity, remove root, washing runs through, tangent plane dries;
9, Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
10, Fructus Jujubae: pick clean impurity, dry;
11, Semen Armeniacae Amarum: pick clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, in leaching cold water, sloughs seed coat, dries, and winnows with a dustpan clean;
12, Concha Ostreae: clean, dry, pulverize use;
13, Herba Rostellulariae: gather after the beginning of autumn, dries;
14, Cortex Acanthopancis: pick clean impurity, wash, slightly section after profit, dry;
15, Folium et Ramulus Clerodendri Trichotomi: pick roguing grass, with clear water slightly leaching, runs through, is cut into the segment of l centimeter length, dries, raw use;
16, Herba Artemisiae Anomalae: pick clean impurity, remove root, uses water edulcoration, slightly soaks, cutting, dry;
17, Herba Spirodelae: 6-9 fishes between the month, dries;
18, Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;
19, Stigma Maydis: get crude drug, removing impurity, sieve dedust bits;
20, Herba Pyrolae: pick decontamination, sieve removes silt, cleans, slightly moistens, chop up, dry;
21, Herba Verbenae: pick clean impurity, cleans, softens cutting, dry;
22, Periostracum Cicadae: pick decontamination, cleans and dries;
23, Cordyceps: removing impurity;
24, Folium Isatidis: pick decontamination and dead leaf, cleans, slightly moistens, cutting, dry;
25, Herba Dianthi: pick clean impurity, removing undesirable root, cleans, stews to moisten, cutting, dry;
26, Calyx Seu Fructus Physalis: removing impurity, fruit stem;
27, Radix Pseudostellariae: extract fibrous root, dry;
28, Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;
29, Cortex Mori: brush away ash bits, clean, run through rear shredding, dry;
30, Herba Eupatorii: pick clean impurity, wash, pull out, slightly after profit, removing undesirable root, cutting, dries;
31, Spora Lygodii: cut off stem and leaf, be placed on be lined with paper or cloth basket in, dry in lee: then rub with hand rubbing, shake, the spore of blade back come off, then with dusting cover sieve remove stem and leaf.
Two, prepare
1, the Fructus Rosae Laevigatae of described weight, Herba Hedyotidis Diffusae, Herba Pogostemonis, Pericarpium Granati, Radix Mimosae Pudicae, Herba Leonuri, Pericarpium Arecae, Herba Cirsii, Flos Sophorae, Fructus Jujubae, Semen Armeniacae Amarum, Concha Ostreae, Herba Rostellulariae, Cortex Acanthopancis, Folium et Ramulus Clerodendri Trichotomi, Herba Artemisiae Anomalae, Herba Spirodelae, Spina Gleditsiae, Stigma Maydis, Herba Pyrolae, Herba Verbenae, Periostracum Cicadae, Cordyceps, Folium Isatidis, Herba Dianthi, Calyx Seu Fructus Physalis, Radix Pseudostellariae, Herba Menthae, Cortex Mori, Herba Eupatorii, Spora Lygodii are decocted with water twice, add water 8 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor.
2, add water the medicinal residues after first time filtration 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor.
3, merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 8 doses to take.
Medicine of the present invention has heat-clearing and toxic substances removing, inducing diuresis and reducing edema function, is used for the treatment of acute glomerulonephritis of baby instant effect, good effect, does not recur.Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 100 examples for medical treatment.
2, diagnostic criteria
After streptococcal infection, through 1 ~ 3 week asymptomatic intermission, there is edema, hypertension, hematuria.Acute stage, has antistreptolysin " 0 " to tire to increase more, SC lowering of concentration, and in urine, FDP content to increase etc. and more contributes to diagnosis.Few patients has with acute congestive heart failure or hypertensive encephalopathy for originally symptom, or sickly just only has edema and hypertension and only have slight or without routine urinalysis change etc.
3, Therapeutic Method
Selecting above-mentioned medicament, take to patient, every day 2 times, each 1 dose, 15 days is a course for the treatment of, takes three courses for the treatment of continuously.
4, efficacy assessment standard
Effective: acute glomerulonephritis of baby symptom is fully recovered, recover normal;
Take a turn for the better: acute glomerulonephritis of baby symptom alleviates, and the state of an illness progressively takes a turn for the better;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy acute glomerulonephritis of baby patient 100 example of the present invention, effective 91 examples of result, obvious effective rate is 91%, and take a turn for the better 2 examples, and improvement rate is 2%, and invalid 7 examples, total effective rate is 93%.
Claims (3)
1. treat a medicine for acute glomerulonephritis of baby, it is characterized in that: it is made up of the crude drug in following weight range:
Fructus Rosae Laevigatae 10-20 gram of Herba Hedyotidis Diffusae 5-15 gram of Herba Pogostemonis 6-16 gram
Pericarpium Granati 8-16 gram of Radix Mimosae Pudicae 10-18 gram of Herba Leonuri 8-20 gram
Pericarpium Arecae 8-15 gram of Herba Cirsii 6-15 gram of Flos Sophorae 8-16 gram
Fructus Jujubae 6-15 gram of Semen Armeniacae Amarum 8-15 gram of Concha Ostreae 5-15 gram
Herba Rostellulariae 5-12 gram of Cortex Acanthopancis 5-10 gram of Folium et Ramulus Clerodendri Trichotomi 5-18 gram
Herba Artemisiae Anomalae 8-16 gram of Herba Spirodelae 10-20 gram of Spina Gleditsiae 6-15 gram
Stigma Maydis 8-18 gram of Herba Pyrolae 6-16 gram of Herba Verbenae 10-20 gram
Periostracum Cicadae 3-8 gram of Cordyceps 5-10 gram of Folium Isatidis 10-20 gram
Herba Dianthi 6-15 gram of Calyx Seu Fructus Physalis 5-12 gram of Radix Pseudostellariae 4-8 gram
Herba Menthae 6-15 gram of Cortex Mori 5-15 gram of Herba Eupatorii 5-12 gram
Spora Lygodii 6-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Fructus Rosae Laevigatae 12 grams of Herba Hedyotidis Diffusaes 8 grams of Herba Pogostemoniss 8 grams
Pericarpium Granati 10 grams of Radix Mimosae Pudicaes 12 grams of Herba Leonuris 10 grams
10 grams, Pericarpium Arecae 10 grams of Herba Cirsiis 9 grams of Flos Sophoraes
Fructus Jujubae 8 grams of Semen Armeniacae Amarums 10 grams of Concha Ostreaes 8 grams
Herba Rostellulariae 8 grams of Cortex Acanthopanciss 6 grams of Folium et Ramulus Clerodendri Trichotomis 6 grams
Herba Artemisiae Anomalae 9 grams of Herba Spirodelaes 12 grams of Spina Gleditsiaes 8 grams
Stigma Maydis 10 grams of Herba Pyrolaes 8 grams of Herba Verbenae 10 grams
Periostracum Cicadae 5 grams of Cordyceps 8 grams of Folium Isatidiss 12 grams
Herba Dianthi 8 grams of Calyx Seu Fructus Physaliss 6 grams of Radix Pseudostellariaes 5 grams
Herba Menthae 8 grams of Cortex Mori 6 grams of Herba Eupatoriis 8 grams
Spora Lygodii 8 grams.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Fructus Rosae Laevigatae: pick decontamination, cuts two lobes, slightly soaks with water, pull out, and after moistening, the residual burr of removing, digs clean hair, core, dry;
(2) Herba Hedyotidis Diffusae: get crude drug, removing impurity, wash quickly is clean, slightly dries in the air, cutting, dry, sieve dedust bits;
(3) Herba Pogostemonis: pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;
(4) Pericarpium Granati: pick decontamination, removes residual interior flesh and son, and clean, stripping and slicing, dries;
(5) Radix Mimosae Pudicae: summer, autumn gather, and clean, dry;
(6) Herba Leonuri: pick decontamination, cleans, runs through, cutting, dry;
(7) Pericarpium Arecae: pick clean impurity, rolloff makes soft, beats, sieve removes spare;
(8) Herba Cirsii: pick clean impurity, remove root, washing runs through, tangent plane dries;
(9) Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
(10) Fructus Jujubae: pick clean impurity, dry;
(11) Semen Armeniacae Amarum: pick clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, in leaching cold water, sloughs seed coat, dries, and winnows with a dustpan clean;
(12) Concha Ostreae: clean, dry, pulverize use;
(13) Herba Rostellulariae: gather after the beginning of autumn, dries;
(14) Cortex Acanthopancis: pick clean impurity, wash, slightly section after profit, dry;
(15) Folium et Ramulus Clerodendri Trichotomi: pick roguing grass, with clear water slightly leaching, runs through, is cut into the segment of l centimeter length, dries, raw use;
(16) Herba Artemisiae Anomalae: pick clean impurity, remove root, uses water edulcoration, slightly soaks, cutting, dry;
(17) Herba Spirodelae: 6-9 fishes between the month, dries;
(18) Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;
(19) Stigma Maydis: get crude drug, removing impurity, sieve dedust bits;
(20) Herba Pyrolae: pick decontamination, sieve removes silt, cleans, slightly moistens, chop up, dry;
(21) Herba Verbenae: pick clean impurity, cleans, softens cutting, dry;
(22) Periostracum Cicadae: pick decontamination, cleans and dries;
(23) Cordyceps: removing impurity;
(24) Folium Isatidis: pick decontamination and dead leaf, cleans, slightly moistens, cutting, dry;
(25) Herba Dianthi: pick clean impurity, removing undesirable root, cleans, stews to moisten, cutting, dry;
(26) Calyx Seu Fructus Physalis: removing impurity, fruit stem;
(27) Radix Pseudostellariae: extract fibrous root, dry;
(28) Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;
(29) Cortex Mori: brush away ash bits, clean, run through rear shredding, dry;
(30) Herba Eupatorii: pick clean impurity, wash, pull out, slightly after profit, removing undesirable root, cutting, dries;
(31) Spora Lygodii: cut off stem and leaf, be placed on be lined with paper or cloth basket in, dry in lee: then rub with hand rubbing, shake, the spore of blade back come off, then with dusting cover sieve remove stem and leaf;
(2) prepare
(1) Fructus Rosae Laevigatae of described weight, Herba Hedyotidis Diffusae, Herba Pogostemonis, Pericarpium Granati, Radix Mimosae Pudicae, Herba Leonuri, Pericarpium Arecae, Herba Cirsii, Flos Sophorae, Fructus Jujubae, Semen Armeniacae Amarum, Concha Ostreae, Herba Rostellulariae, Cortex Acanthopancis, Folium et Ramulus Clerodendri Trichotomi, Herba Artemisiae Anomalae, Herba Spirodelae, Spina Gleditsiae, Stigma Maydis, Herba Pyrolae, Herba Verbenae, Periostracum Cicadae, Cordyceps, Folium Isatidis, Herba Dianthi, Calyx Seu Fructus Physalis, Radix Pseudostellariae, Herba Menthae, Cortex Mori, Herba Eupatorii, Spora Lygodii are decocted with water twice, add water 8 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor;
(2) add water the medicinal residues after first time filtration 6 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor;
(3) merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 8 doses to take.
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