CN103648525B - 靶向间皮素的重组免疫毒素 - Google Patents
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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JP (2) | JP6169561B2 (fr) |
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CN (1) | CN103648525B (fr) |
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CA (1) | CA2835070C (fr) |
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ATE524489T1 (de) | 2005-07-29 | 2011-09-15 | Us Gov Health & Human Serv | Mutierte pseudomonas-exotoxine mit reduzierter antigenität |
AU2006338562A1 (en) | 2005-11-03 | 2007-08-30 | Genentech, Inc. | Therapeutic anti-HER2 antibody fusion polypeptides |
CA2661634C (fr) | 2006-09-06 | 2017-03-28 | The Regents Of The University Of California | Peptides antimicrobiens cibles selectivement et leur utilisation |
CN102655882B (zh) | 2009-09-11 | 2014-11-19 | 美国政府健康及人类服务部 | 具有降低的免疫原性的改进的假单胞菌外毒素a |
MX2013012905A (es) | 2011-05-06 | 2014-04-25 | Us Gov Health & Human Serv | Inmunotoxina recombinante dirigida a la mesotelina. |
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Patent Citations (2)
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US7081518B1 (en) * | 1999-05-27 | 2006-07-25 | The United States Of America As Represented By The Department Of Health And Human Services | Anti-mesothelin antibodies having high binding affinity |
WO2009032954A1 (fr) * | 2007-09-04 | 2009-03-12 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Délétions dans le domaine ii de l'exotoxine a de pseudomonas qui réduisent la toxicité non spécifique |
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PE20141454A1 (es) | 2014-10-23 |
EP2704739A1 (fr) | 2014-03-12 |
CL2013003182A1 (es) | 2014-08-22 |
CN103648525A (zh) | 2014-03-19 |
ECSP13013067A (es) | 2015-04-30 |
RU2600067C2 (ru) | 2016-10-20 |
CR20130571A (es) | 2014-02-27 |
EP2704739B1 (fr) | 2017-07-12 |
ZA201308270B (en) | 2016-08-31 |
CA2835070C (fr) | 2021-07-06 |
MA35244B1 (fr) | 2014-07-03 |
WO2012154530A1 (fr) | 2012-11-15 |
SG194787A1 (en) | 2013-12-30 |
IL229198A0 (en) | 2014-01-30 |
JP2017140029A (ja) | 2017-08-17 |
JP6169561B2 (ja) | 2017-07-26 |
NZ617386A (en) | 2015-05-29 |
KR20140036216A (ko) | 2014-03-25 |
US10683362B2 (en) | 2020-06-16 |
US20140154248A1 (en) | 2014-06-05 |
CO6862104A2 (es) | 2014-02-10 |
ES2641877T3 (es) | 2017-11-14 |
AU2012253896A1 (en) | 2013-11-21 |
JP2014515921A (ja) | 2014-07-07 |
BR112013028537A2 (pt) | 2017-01-17 |
MX2013012905A (es) | 2014-04-25 |
RU2013148919A (ru) | 2015-06-20 |
AU2012253896B2 (en) | 2016-09-22 |
CA2835070A1 (fr) | 2012-11-15 |
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