CN103623454B - 一种高通透率薄膜敷料 - Google Patents
一种高通透率薄膜敷料 Download PDFInfo
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- CN103623454B CN103623454B CN201310613174.0A CN201310613174A CN103623454B CN 103623454 B CN103623454 B CN 103623454B CN 201310613174 A CN201310613174 A CN 201310613174A CN 103623454 B CN103623454 B CN 103623454B
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- Prior art keywords
- polyurethane
- rete
- polyurethane elastomer
- film dressing
- penetration rate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920003225 polyurethane elastomer Polymers 0.000 claims abstract description 35
- 239000010410 layer Substances 0.000 claims abstract description 25
- 229920002635 polyurethane Polymers 0.000 claims description 28
- 239000004814 polyurethane Substances 0.000 claims description 28
- 230000035515 penetration Effects 0.000 claims description 24
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 18
- 239000003522 acrylic cement Substances 0.000 claims description 12
- 229920005749 polyurethane resin Polymers 0.000 claims description 12
- 229920001730 Moisture cure polyurethane Polymers 0.000 claims description 10
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 10
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 10
- 229910052710 silicon Inorganic materials 0.000 claims description 10
- 239000010703 silicon Substances 0.000 claims description 10
- UKLDJPRMSDWDSL-UHFFFAOYSA-L [dibutyl(dodecanoyloxy)stannyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)O[Sn](CCCC)(CCCC)OC(=O)CCCCCCCCCCC UKLDJPRMSDWDSL-UHFFFAOYSA-L 0.000 claims description 8
- 239000000853 adhesive Substances 0.000 claims description 7
- 230000001070 adhesive effect Effects 0.000 claims description 7
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- FWDBOZPQNFPOLF-UHFFFAOYSA-N ethenyl(triethoxy)silane Chemical compound CCO[Si](OCC)(OCC)C=C FWDBOZPQNFPOLF-UHFFFAOYSA-N 0.000 claims description 6
- JBTWLSYIZRCDFO-UHFFFAOYSA-N ethyl methyl carbonate Chemical compound CCOC(=O)OC JBTWLSYIZRCDFO-UHFFFAOYSA-N 0.000 claims description 6
- 229920002523 polyethylene Glycol 1000 Polymers 0.000 claims description 6
- DXPPIEDUBFUSEZ-UHFFFAOYSA-N 6-methylheptyl prop-2-enoate Chemical group CC(C)CCCCCOC(=O)C=C DXPPIEDUBFUSEZ-UHFFFAOYSA-N 0.000 claims description 5
- -1 benzene olefin Chemical class 0.000 claims description 5
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 claims description 5
- CCJAYIGMMRQRAO-UHFFFAOYSA-N 2-[4-[(2-hydroxyphenyl)methylideneamino]butyliminomethyl]phenol Chemical compound OC1=CC=CC=C1C=NCCCCN=CC1=CC=CC=C1O CCJAYIGMMRQRAO-UHFFFAOYSA-N 0.000 claims description 4
- 239000006185 dispersion Substances 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 9
- 230000035699 permeability Effects 0.000 abstract description 5
- 229920006264 polyurethane film Polymers 0.000 abstract description 5
- 241000894006 Bacteria Species 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 230000008595 infiltration Effects 0.000 abstract description 2
- 238000001764 infiltration Methods 0.000 abstract description 2
- 239000012790 adhesive layer Substances 0.000 abstract 1
- 239000003344 environmental pollutant Substances 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000012466 permeate Substances 0.000 abstract 1
- 208000001297 phlebitis Diseases 0.000 abstract 1
- 231100000719 pollutant Toxicity 0.000 abstract 1
- 239000010408 film Substances 0.000 description 27
- 206010052428 Wound Diseases 0.000 description 10
- 208000027418 Wounds and injury Diseases 0.000 description 10
- 239000000463 material Substances 0.000 description 8
- 238000000576 coating method Methods 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- 239000010409 thin film Substances 0.000 description 6
- 238000005266 casting Methods 0.000 description 5
- 239000011248 coating agent Substances 0.000 description 5
- 239000004745 nonwoven fabric Substances 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- 230000000149 penetrating effect Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 229920000297 Rayon Polymers 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000006260 foam Substances 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000003292 glue Substances 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- OELQSSWXRGADDE-UHFFFAOYSA-N 2-methylprop-2-eneperoxoic acid Chemical compound CC(=C)C(=O)OO OELQSSWXRGADDE-UHFFFAOYSA-N 0.000 description 1
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 208000032840 Catheter-Related Infections Diseases 0.000 description 1
- 239000004970 Chain extender Substances 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000006664 bond formation reaction Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 238000007306 functionalization reaction Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 208000001875 irritant dermatitis Diseases 0.000 description 1
- 239000012948 isocyanate Substances 0.000 description 1
- 150000002513 isocyanates Chemical class 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 150000003384 small molecules Chemical group 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Laminated Bodies (AREA)
Abstract
Description
配方 | 实施例3 | 实施例4 | 实施例5 | 实施例6 |
MDI | 22.0 | 25.0 | 25.0 | 25.0 |
PEG1000 | 18.0 | 22.0 | 22.0 | 22.0 |
PTMG1000 | 12.0 | 15.0 | 15.0 | 15.0 |
1,4-丁二醇 | 3.2 | 2.8 | 2.8 | 2.8 |
苯烯酸-2-羟基乙酯 | - | - | 5.0 | 5.0 |
丙烯酸异辛酯 | 3.5 | 3.2 | 3.2 | 3.2 |
乙烯基三乙氧基硅烷 | 1.8 | 1.5 | 1.5 | 1.5 |
N-羟甲基丙烯酰胺 | - | - | - | 1.2 |
二月桂酸二丁基锡 | 0.20 | 0.25 | 0.25 | 0.25 |
碳酸甲乙酯 | 5.0 | 5.5 | 5.5 | 5.5 |
异丙醇 | 余量 | 余量 | 余量 | 余量 |
配方 | 实施例7 | 比较例1 | 比较例2 | 比较例3 |
MDI | 22.0 | 22.0 | 22.0 | 22.0 |
PEG1000 | 18.0 | 30.0 | 18.0 | 18.0 |
PTMG1000 | 12.0 | - | 12.0 | 12.0 |
1,4-丁二醇 | 3.2 | 3.2 | 3.2 | 3.2 |
苯烯酸-2-羟基乙酯 | 4.2 | - | - | - |
丙烯酸异辛酯 | 3.5 | - | - | 3.5 |
乙烯基三乙氧基硅烷 | 1.8 | 1.8 | 1.8 | 1.8 |
N-羟甲基丙烯酰胺 | 1.0 | - | - | 1.0 |
二月桂酸二丁基锡 | 0.20 | 0.20 | 0.20 | 0.20 |
碳酸甲乙酯 | 5.0 | 5.0 | 5.0 | 5.0 |
异丙醇 | 余量 | 余量 | 余量 | 余量 |
Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310613174.0A CN103623454B (zh) | 2013-11-28 | 2013-11-28 | 一种高通透率薄膜敷料 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310613174.0A CN103623454B (zh) | 2013-11-28 | 2013-11-28 | 一种高通透率薄膜敷料 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103623454A CN103623454A (zh) | 2014-03-12 |
CN103623454B true CN103623454B (zh) | 2015-04-22 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201310613174.0A Active CN103623454B (zh) | 2013-11-28 | 2013-11-28 | 一种高通透率薄膜敷料 |
Country Status (1)
Country | Link |
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CN (1) | CN103623454B (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102455927B1 (ko) * | 2014-07-09 | 2022-10-17 | 루브리졸 어드밴스드 머티어리얼스, 인코포레이티드 | 하이드로겔 조성물 |
CN113604163B (zh) * | 2021-09-01 | 2023-05-09 | 嘉兴林华医用材料有限公司 | 一种透气聚氨酯固定贴膜 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1190723A2 (de) * | 2000-09-22 | 2002-03-27 | Beiersdorf AG | Selbsthaftende Wundverbände mit haftfähigem Wundversorgungsbereich |
CN1462614A (zh) * | 2003-06-24 | 2003-12-24 | 四川大学 | 亲水性聚氨酯创伤敷料及其制备方法 |
CN101801322A (zh) * | 2007-09-28 | 2010-08-11 | 日绊株式会社 | 贴附材料 |
CN103027788A (zh) * | 2013-01-05 | 2013-04-10 | 吴斌 | 一种可吸收性医用敷料及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070179419A1 (en) * | 2006-01-27 | 2007-08-02 | World Properties, Inc. | Low friction coatings for adhesive dressings and method of manufacture thereof |
EP2536312A1 (en) * | 2010-02-19 | 2012-12-26 | Majic Beauty Pty Ltd | Cosmetic applicator |
-
2013
- 2013-11-28 CN CN201310613174.0A patent/CN103623454B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1190723A2 (de) * | 2000-09-22 | 2002-03-27 | Beiersdorf AG | Selbsthaftende Wundverbände mit haftfähigem Wundversorgungsbereich |
CN1462614A (zh) * | 2003-06-24 | 2003-12-24 | 四川大学 | 亲水性聚氨酯创伤敷料及其制备方法 |
CN101801322A (zh) * | 2007-09-28 | 2010-08-11 | 日绊株式会社 | 贴附材料 |
CN103027788A (zh) * | 2013-01-05 | 2013-04-10 | 吴斌 | 一种可吸收性医用敷料及其制备方法 |
Non-Patent Citations (2)
Title |
---|
影响聚醚型聚氨酯弹性体合成的因素;谢富春等;《弹性体》;20101025;第20卷(第5期);第28-31页 * |
聚醚型聚氨酯的结构及其防水透湿特性;权衡等;《印染助剂》;20120930;第29卷(第9期);第8-11页 * |
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Publication number | Publication date |
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CN103623454A (zh) | 2014-03-12 |
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GR01 | Patent grant | ||
DD01 | Delivery of document by public notice |
Addressee: UNION MEDICAL SUPPLIES Co.,Ltd. Document name: Notification to Pay the Fees |
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DD01 | Delivery of document by public notice | ||
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Addressee: UNION MEDICAL SUPPLIES Co.,Ltd. Document name: Notification to Pay the Fees |
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CP03 | Change of name, title or address |
Address after: No.206, Xizhuang village, Huaibei Town, Huairou District, Beijing Patentee after: Beijing shuyikang medical supplies Co.,Ltd. Address before: 100025 Beijing city Chaoyang District village in eight, building 69, Room 102, ocean vista Patentee before: UNION MEDICAL SUPPLIES Co.,Ltd. |
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Effective date of registration: 20200508 Address after: Floor S1-S3, building 14, Zhengzhou airport biomedical park, northeast corner of the intersection of Huanghai Road and the second biotechnology street, airport economic comprehensive experimental zone, Zhengzhou City, Henan Province, 450000 Patentee after: Henan health Guangji Biotechnology Co.,Ltd. Address before: No.206, Xizhuang village, Huaibei Town, Huairou District, Beijing Patentee before: Beijing shuyikang medical supplies Co.,Ltd. |