Summary of the invention
Technical problem to be solved by this invention is to provide a kind of feed that can improve the Chinese herbal feed additive of Egg Production of Laying Hens quality and egg production and comprise this feed addictive, it has low toxicity, have no side effect, the effect of noresidue, can well improve lay eggs quality and the egg production of laying hen.
For solving the problems of the technologies described above, the invention provides a kind ofly for improving the feed of laying hen Egg Quality, it comprises main feed composition, soybean lecithin, Bee Pollen, manna oligosaccharide, salt, bone meal, sodium acid carbonate, calcium carbonate, KI, trace mineral supplement, amino acid additive, vitamin(e) supplement, for improving Chinese herbal feed additive and the microorganism formulation of laying hen Egg Quality.
Wherein, in described feed, the weight portion of each material composition is respectively main feed composition 90 weight portion~110 weight portions, soybean lecithin 2 weight portion~4 weight portions, Bee Pollen 1 weight portion~3 weight portion, manna oligosaccharide 1 weight portion~3 weight portion, salt 1 weight portion~3 weight portion, bone meal 3 weight portion~5 weight portions, sodium acid carbonate 4 weight portion~6 weight portions, calcium carbonate 3 weight portion~5 weight portions, trace mineral supplement 2 weight portion~4 weight portions, amino acid additive 4 weight portion~6 weight portions, vitamin(e) supplement 4 weight portion~6 weight portions, Chinese herbal feed additive 15 weight portion~18 weight portions and microorganism formulation 2 weight portion~4 weight portions.
Wherein, the bulk drug that described Chinese herbal feed additive comprises has barrenwort, eclipta, the stem of noble dendrobium, the Radix Astragali, gypsum, wilsonii, the vine of multiflower knotweed, cape jasmine, Radix Liriopes, Psoralea corylifolia, Semen sesami nigrum, thizoma curculiginis, parasitic loranthus, Chinese yam, Common St.Paulswort Herb, Galanga Galangal Seed, galangal, sea-buckthorn, asafoetide, the membrane of a chicken's gizzard, cuttlebone, the red sage root, east wind dish, meadow pine and cymbopogon distans.
In described Chinese herbal feed additive, the weight portion of each bulk drug is respectively barrenwort 60 weight portion~70 weight portions, eclipta 30 weight portion~40 weight portions, the stem of noble dendrobium 25 weight portion~35 weight portions, the Radix Astragali 50 weight portion~60 weight portions, gypsum 45 weight portion~55 weight portions, wilsonii 35 weight portion~45 weight portions, the vine of multiflower knotweed 20 weight portion~30 weight portions, cape jasmine 15 weight portion~25 weight portions, Radix Liriopes 20 weight portion~30 weight portions, Psoralea corylifolia 35 weight portion~45 weight portions, Semen sesami nigrum 20 weight portion~30 weight portions, thizoma curculiginis 25 weight portion~35 weight portions, parasitic loranthus 15 weight portion~25 weight portions, Chinese yam 25 weight portion~35 weight portions, Common St.Paulswort Herb 20 weight portion~30 weight portions, Galanga Galangal Seed 25 weight portion~35 weight portions, galangal 20 weight portion~30 weight portions, sea-buckthorn 25 weight portion~35 weight portions, asafoetide 20 weight portion~30 weight portions, the membrane of a chicken's gizzard 25 weight portion~35 weight portions, cuttlebone 30 weight portion~40 weight portions, the red sage root 25 weight portion~35 weight portions, east wind dish 25 weight portion~35 weight portions, meadow pine 20 weight portion~30 weight portions and cymbopogon distans 25 weight portion~35 weight portions.
Further preferably, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively barrenwort 63 weight portion~67 weight portions, eclipta 33 weight portion~37 weight portions, the stem of noble dendrobium 28 weight portion~32 weight portions, the Radix Astragali 53 weight portion~57 weight portions, gypsum 48 weight portion~52 weight portions, wilsonii 38 weight portion~42 weight portions, the vine of multiflower knotweed 23 weight portion~27 weight portions, cape jasmine 18 weight portion~22 weight portions, Radix Liriopes 23 weight portion~27 weight portions, Psoralea corylifolia 38 weight portion~42 weight portions, Semen sesami nigrum 23 weight portion~27 weight portions, thizoma curculiginis 28 weight portion~32 weight portions, parasitic loranthus 18 weight portion~22 weight portions, Chinese yam 28 weight portion~32 weight portions, Common St.Paulswort Herb 23 weight portion~27 weight portions, Galanga Galangal Seed 28 weight portion~32 weight portions, galangal 23 weight portion~27 weight portions, sea-buckthorn 28 weight portion~32 weight portions, asafoetide 23 weight portion~27 weight portions, the membrane of a chicken's gizzard 28 weight portion~32 weight portions, cuttlebone 33 weight portion~37 weight portions, the red sage root 28 weight portion~32 weight portions, east wind dish 28 weight portion~32 weight portions, meadow pine 23 weight portion~27 weight portions and cymbopogon distans 28 weight portion~32 weight portions.
Wherein, the preparation method of described Chinese herbal feed additive, is specially:
Above-mentioned raw materials medicine component is mixed by weight, obtain mixture, put into reactor, add the water with respect to 3~5 times of mixture qualities, slow fire heating decocts 2~4 hours, and decoction liquor is filtered, filter residue adds the water with respect to 2~4 times of the mixture qualities obtaining above, and slow fire boiling is 1~3 hour again, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
The present invention also provides the preparation method of above-mentioned feed, and it comprises:
The first step, get 3kg microbe additive and join in 100kg~120kg water and mix, obtain zymotic fluid, the zymotic fluid that 100kg is obtained joins in 100kg main feed composition, evenly pack sealing, is placed in the environment of 20 ℃~30 ℃ and obtains fermentation material after 10~20 days;
Second step, prepares Chinese herbal feed additive according to the method described above;
The 3rd step, together with the Chinese herbal feed additive that the fermentation material that the first step is obtained obtains with second step and other components, put into fodder mixing machine, continuous uniform stirred after 1~3 hour, putting into pulverizer tentatively pulverizes, after taking-up, putting into micronizer, to carry out separating twice be fine grained again, the feed that gets product after sterilization, sealing, pack of the fine grained after pulverizing.
It is a kind of for improving the Chinese herbal feed additive of laying hen Egg Quality that the present invention also provides, and it bulk drug comprising has barrenwort, eclipta, the stem of noble dendrobium, the Radix Astragali, gypsum, wilsonii, the vine of multiflower knotweed, cape jasmine, Radix Liriopes, Psoralea corylifolia, Semen sesami nigrum, thizoma curculiginis, parasitic loranthus, Chinese yam, Common St.Paulswort Herb, Galanga Galangal Seed, galangal, sea-buckthorn, asafoetide, the membrane of a chicken's gizzard, cuttlebone, the red sage root, east wind dish, meadow pine and cymbopogon distans.
Wherein, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively barrenwort 60 weight portion~70 weight portions, eclipta 30 weight portion~40 weight portions, the stem of noble dendrobium 25 weight portion~35 weight portions, the Radix Astragali 50 weight portion~60 weight portions, gypsum 45 weight portion~55 weight portions, wilsonii 35 weight portion~45 weight portions, the vine of multiflower knotweed 20 weight portion~30 weight portions, cape jasmine 15 weight portion~25 weight portions, Radix Liriopes 20 weight portion~30 weight portions, Psoralea corylifolia 35 weight portion~45 weight portions, Semen sesami nigrum 20 weight portion~30 weight portions, thizoma curculiginis 25 weight portion~35 weight portions, parasitic loranthus 15 weight portion~25 weight portions, Chinese yam 25 weight portion~35 weight portions, Common St.Paulswort Herb 20 weight portion~30 weight portions, Galanga Galangal Seed 25 weight portion~35 weight portions, galangal 20 weight portion~30 weight portions, sea-buckthorn 25 weight portion~35 weight portions, asafoetide 20 weight portion~30 weight portions, the membrane of a chicken's gizzard 25 weight portion~35 weight portions, cuttlebone 30 weight portion~40 weight portions, the red sage root 25 weight portion~35 weight portions, east wind dish 25 weight portion~35 weight portions, meadow pine 20 weight portion~30 weight portions and cymbopogon distans 25 weight portion~35 weight portions.
The preparation method of described Chinese herbal feed additive, is specially:
Above-mentioned raw materials medicine component is mixed by weight, obtain mixture, put into reactor, add the water with respect to 3~5 times of mixture qualities, slow fire heating decocts 2~4 hours, and decoction liquor is filtered, filter residue adds the water with respect to 2~4 times of the mixture qualities obtaining above, and slow fire boiling is 1~3 hour again, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
Beneficial effect of the present invention:
Chinese medicine composition feed addictive provided by the invention and feed, it has low toxicity, has no side effect, the effect of noresidue, can well improve lay eggs quality and the egg production of laying hen.
The specific embodiment
The invention provides a kind ofly for improving the feed of laying hen Egg Quality, it comprises main feed composition, soybean lecithin, Bee Pollen, manna oligosaccharide, salt, bone meal, sodium acid carbonate, calcium carbonate, KI, trace mineral supplement, amino acid additive, vitamin(e) supplement, for improving Chinese herbal feed additive and the microorganism formulation of laying hen Egg Quality.
Wherein, in described feed, the weight portion of each material composition is respectively main feed composition 90 weight portion~110 weight portions, soybean lecithin 2 weight portion~4 weight portions, Bee Pollen 1 weight portion~3 weight portion, manna oligosaccharide 1 weight portion~3 weight portion, salt 1 weight portion~3 weight portion, bone meal 3 weight portion~5 weight portions, sodium acid carbonate 4 weight portion~6 weight portions, calcium carbonate 3 weight portion~5 weight portions, trace mineral supplement 2 weight portion~4 weight portions, amino acid additive 4 weight portion~6 weight portions, vitamin(e) supplement 4 weight portion~6 weight portions, Chinese herbal feed additive 15 weight portion~18 weight portions and microorganism formulation 2 weight portion~4 weight portions.
Further preferably, in described feed, the weight portion of each material composition is respectively main feed composition 100 weight portions, soybean lecithin 3 weight portions, Bee Pollen 2 weight portions, manna oligosaccharide 2 weight portions, salt 2 weight portions, bone meal 4 weight portions, sodium acid carbonate 5 weight portions, calcium carbonate 4 weight portions, trace mineral supplement 3 weight portions, amino acid additive 5 weight portions, vitamin(e) supplement 5 weight portions, Chinese herbal feed additive 16 weight portions and microorganism formulation 3 weight portions.
Sodium acid carbonate (sodium bicarbonate, NaHCO
3) be feed addictive conventional in aquaculture.Be used on the one hand anti-heat stress, alleviate livestock and poultry acid poisoning, increase body fluid alkali storage content; On the other hand, bicarbonate radical (HCO
- 3) as buffer composition, for maintaining the normal acid-base balance of body, osmotic pressure is significant.In diet, add appropriate NaHCO
3not only can improve performance in layers, be conducive to promote the improvement of eggshell quality, NaHCO simultaneously
3raising to performance in layers is significant, and it is not only conducive to safeguard body acid-base balance, also can be eggshell formation enough carbonates are provided.
Soybean lecithin is the mixture of various phosphoglycerides and derivative thereof in soybean, it is the bioactivator with different physiological roles, mainly comprise lecithin, cephalin, phosphatidylinositols and serinephosphatide, soybean lecithin has the integrality of Cell protection membrane structure and function, anti-oxidant, reducing blood lipid, the effects such as regulation and control fat metabolism, can improve feed intake and the production performance of poultry, improve the health status of poultry, soybean lecithin adds in mixed feed can reduce the dust in mixed feed, thereby reduce the generation of livestock and birds respiratory disease, can prevent the automatic classification of dust from flying and feed, to keeping feed mixture homogeneity to there is good effect, the property balanced in nutrition that has kept daily ration, phosphatide has good lubricity, can reduce equipment attrition, reduce energy consumption simultaneously, and the temperature arrising caused by friction that makes feed reduces to minimum, phospholipid molecule has hydrophilic and two groups of oleophylic, therefore phosphatide is good fat emulsifier, can protect the unrighted acid in feed, improve the Quality and yield of granulating, can save the consumption of poultry to methionine, a large amount of liposoluble vitamins is provided, thereby can improve antioxidant levels fatty in feed.
Bee Pollen contains abundant amino acid, organized enzyme, vitamin, trace element and auxin etc., can supplement and balanced feed in essential nutritional labeling, be conducive to digesting and assimilating of body, promote growth, improve weightening finish, minimizing feedstuff-meat ratio.And that propolis contains corresponding glue source plant is similar, the concentrate of mass efficient active component, can accelerate the metabolic process of body, promotes growing of body.
Manna oligosaccharide can be controlled micro-ecological environment in intestines and stomach, promote the propagation of beneficial bacterium, suppress the field planting of harmful bacteria, thereby maintain normal stool road environment, there is the acceptor competitive adsorption with harmful bacteria, stop germ to be combined with animal intestinal epithelial cell, thereby accelerating bacterium discharges from enteron aisle, promote the effect of intestinal microecology balance, there is certain immunogenicity, can stimulate immune response reaction, and energy and some viruses, toxin and fungal cell's surface conjunction is as the adjuvant of these exogenous antigens, and then slow down the absorption of antigen, increase tiring of antigen, promote the glycoprotein of emiocytosis manna oligosaccharide base, these glycoprotein can be in conjunction with the bacterium of invading human body, trigger the multistage immunologic function of body, and strengthen the protection usefulness of flora, strengthen animal body fluid and cellular immunity.
Trace mineral supplement can be the trace mineral supplement of various routines, can use simple acylate, as ironic citrate, also can use trace element and amino-acid chelate, as amino acid iron, the trace element adding mainly contains iron, zinc, copper, manganese, iodine, cobalt, selenium, molybdenum, also can use composite trace element premix, the Great Britain and America who provides as Beijing You Libao biotechnology Co., Ltd you.
Microorganism formulation, in the process of fermented feed, generates on the one hand carbohydrate, amino acids, a large number of nutrients such as protein-based, and it can directly increase the nutrition of cultivation body body; On the other hand, enter the dominant population that cultivation body enteron aisle forms useful viable bacteria, can improve the enteric microorganism ecosystem; Each beneficial bacterium can, by a series of biochemical reactions, produce physiological activator again under good condition.As various digestive ferments, metabolic enzyme, endocrine hormone etc., not only strengthen anti pathologic immunity ability, reduce disease, but also accelerate, to the digesting and assimilating of feed nutrient, to promote growth, put on weight, the price of deed improves.In addition, colony house stink alleviates, environmental sanitary quality improves, also be conducive to growing up healthy and sound of livestock, described microorganism formulation can be Lactobacillus casei, lactobacillus lactis, Lactobacillus plantarum, lactoenterococcus, Pediococcus pentosaceus, yeast, candida utili, swamp Rhodopseudomonas, bacillus subtilis, bacillus licheniformis, lactic acid bacteria, one or more combine, as source health precious (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides), this microorganism formulation primary raw material comprises product enzyme bacillus, lactic acid bacteria, saccharomycete, zytase, mannase, glucolase, amylase etc., effective viable bacteria content >=10,000,000,000/gram.
Feed ingredient comprises one or more mixing in corn, Chinese sorghum, wheat bran, dregs of beans, at least has corn.
Amino acid additive comprises the various conventional amino acid such as serine, glutamic acid, glycine, isoleucine, leucine, alanine, proline, also can adopt amino acid premix, the composite aminophenol powder that as above sea cowry energy Chemical Co., Ltd. produces.
Vitamin(e) supplement comprises the various conventional vitamins such as riboflavin, vitamin C, vitamin E, vitamin A, Cobastab, also can adopt vitamin premix, as plain in the excellent dimension that Beijing You Libao Bioisystech Co., Ltd produces.
Further, described feed only consists of above-mentioned raw materials.
Described have barrenwort, eclipta, the stem of noble dendrobium, the Radix Astragali, gypsum, wilsonii, the vine of multiflower knotweed, cape jasmine, Radix Liriopes, Psoralea corylifolia, Semen sesami nigrum, thizoma curculiginis, parasitic loranthus, Chinese yam, Common St.Paulswort Herb, Galanga Galangal Seed, galangal, sea-buckthorn, asafoetide, the membrane of a chicken's gizzard, cuttlebone, the red sage root, east wind dish, meadow pine and cymbopogon distans for improving the bulk drug that the Chinese herbal feed additive of laying hen Egg Quality comprises.
Barrenwort: taste is pungent, sweet, warm in nature, enters liver, kidney channel, has kidney-replenishing, strengthening the bones and muscles, the effect of wines used as antirheumatic,, cold extremities with aversion to cold soft for impotence due to deficiency of the kidney, seminal emission premature ejaculation, waist knee impotence; The cards such as numbness and ache of cold dampness or spasm of limbs are numb.
Eclipta: taste is sweet, sour, cold in nature, returns liver, kidney channel, and play and tonify the liver and kidney, the effect of cooling blood and hemostasis, for having a dizzy spell due to the deficiency of liver-yin and kidney-yin, blurring of vision, soreness and weakness of waist and knees; Be suitable for the deficiency of Yin and have hot person, be used for the treatment of the haematemesis of accumulated heat in stomach, the symptoms such as the hemoptysis of heat impairing pulmonary collateral, eclipta has inhibitory action to staphylococcus aureus, typhoid bacillus, Song's Shigella flexneri, Pseudomonas aeruginosa, can obviously strengthen nospecific immunity and cellular immune function.
The stem of noble dendrobium: cold nature, taste is sweet, enters stomach, kidney channel, has reinforcing stomach reg fluid, nourishing Yin and clearing heat, the effect of moistening lung kidney-nourishing, for heat consuming body fluid, low-heat polydipsia, the red few tongue of tongue; Deficiency of stomach-Yin, thirsty and dry pharynx, the contrary few food of vomitting, vague epigastralgia, the few tongue of tongue light; The deficiency of the kidney yin, the cards such as blurring of vision.
The Radix Astragali: taste is sweet, warm in nature, enter spleen, lung channel, there is benefit strengthening spleen and lung, elevate a turnable ladder yang-energy, strengthening exterior and reducing sweat, the effects such as holder sore myogenic, are mainly used in the weak anorexia and loose stool due to spleen-lung Qi deficiency, palpitation, the visceral organ ptosis of the sinking of qi of middle-jiao, Qi dysfunction in blood control uterine bleeding is had blood in stool, and rushes down for a long time prolapse of the anus; The spontaneous sweating of exterior deficiency, the cards such as insufficiency of vital energy and blood.
Gypsum: taste is pungent, sweet, property Great Cold, enter lung, stomach warp, there is clearing heat-fire, the quench the thirst effect of relieving restlessness, the all thin and matter weights of its smell, the reality heat of energy removing summer-heat stomach of foot Yang Ming, filling the air for the treatment of pathogen invading YANG MING is high hot, profuse sweating, thirsty, vexed, the symptoms such as arteries and veins flood, key medicine for the bright stomach warp of sun, to epidemic meningitis, encephalitis, high heat due to pneumonia etc. has good antipyretic effect, and have relieving convulsion effect concurrently, also can be used for the burning pain in the epigastrium due to the high Sheng of stomach fire, headache, aphthae and summer-heat and damp dysphoria with smothery sensation, lung heat is coughed and is breathed heavily, restlessness and thirst, damp and hot obstruction of meridian, the cards such as the hot numbness of arthralgia.
Wilsonii: taste is pungent, bitter, micro-sweet, warm in nature, enters spleen, kidney, the heart channel of Hang-Shaoyin, have and replenish qi to invigorate the spleen, tonify the kidney to relieve mental strain, the effect of dispelling rheumatism, soft for wind-cold-dampness arthralgia, lumbocrural pain, muscles and bones impotence, be slow in action, the card such as body void is frail, traumatic injury, fracture, oedema, beriberi, uncontrolled urination are itched.
The vine of multiflower knotweed: sweet, the micro-hardship of taste, property is flat; The thoughts of returning home, Liver Channel, having can mental-tranquilization, the effect of dispelling wind and removing obstruction in the meridians, cures mainly insomnia and dreamful sleep, deficiency of blood bodily pain, numbness, arthralgia due to wind-dampness, the cards such as wind sore mange.
Cape jasmine: latin name Gardeniae Fructus, bitter, cold in nature, enter the heart, lung, three warmers, have the effect of relieving restlessness purging intense heat, soothing liver-qi stagnation, clearing heat and promoting diuresis, cooling blood and hemostasis, be mainly used in the strongly fragrant chest gastral cavity of warm heat disease heat vexed uneasiness, bother not peaceful; Liver depression is not relaxed or Liver Channel has having a dizzy spell of heat, pain in chest and hypochondrium, hot eyes dry throat; Jaundice with damp-heat pathogen; The cards such as the abdominal distention of qi depression to blood stasis.
Radix Liriopes: sweet, the micro-hardship of taste, cold nature, the thoughts of returning home, lung, stomach warp, have nourishing Yin and promoting production of body fluid, the effect that moistening lung clears away heart-fire, for dryness of the lung dry cough, cough due to consumptive disease, Tianjin wound is thirsty, vexed insomnia, the cards such as the dry constipation of intestines.
Psoralea corylifolia: taste is pungent, bitter, warm in nature, enters kidney, the spleen channel, has tonifying kidney and strengthening yang, and warming spleen and stopping diarrha effect, is mainly used in the Yang-function insufficiency of kidneyzang, the waist knee crymodynia of below element deficiency and cold, frequent urination and enuresis, impotence lingering diarrhea; The insufficiency of the kidney yang, spleen soil lose the stomachache limb of temperature and tremble with fear, Diarrhoea, and Psoralea corylifolia also has the effect of antidiarrheal.
Semen sesami nigrum: taste is sweet, property is flat, returns liver, kidney, large intestine channel, has filling liver kidney, benefiting essence-blood, the effect that ease constipation is dry, for dizzy, Hiccough and deaf, poliosis, post disease alopecia, the cards such as the dry constipation of intestines.
Thizoma curculiginis: taste is pungent, warm in nature, return kidney, Liver Channel, there is warm kidney yang, the effect strengthening the bone, cures mainly impotence cold sperm, aconuresis, uterine bleeding, trusted subordinate's crymodynia, cold arthralgia of loins and legs, ulcer, scrofula, the deficiency of yang is cold the card such as rushes down.
Parasitic loranthus: bitter, sweet, property is flat, enters liver, kidney channel, have the effect of filling liver kidney, strengthening the bones and muscles, wines used as antirheumatic, antiabortive unit, for the soreness of waist pain due to kidney deficiency and liver, muscles and bones impotence is soft, the foot and knee being feeble, kidney deficiency and liver, essence and blood is empty to be lost, the fetal irritability of liability to be abortion, the cards such as waist abdomen pain.
Chinese yam: taste is sweet, property is flat, enters lung, spleen, stomach warp, has tonifying spleen nourishing the stomach, and beneficial lung reinforces the kidney, the effect of nourishing Yin and promoting production of body fluid, cure mainly weakness of the spleen and the stomach, the card such as it is poor that the food of the dysfunction of the spleen in transport is received less, the vexed diarrhoea of gastral cavity.
Common St.Paulswort Herb: latin name Siegesbeckiae Herba, taste is cold, pungent, bitter, returns Liver Channel, kidney channel, has wines used as antirheumatic, sharp joint, the effect of removing toxic substances, cures mainly the cards such as arthralgia due to wind-dampness, muscles and bones are unable, soreness and weakness of waist and knees, quadriplegia, hemiplegia, the wet sore of rubella.
Galanga Galangal Seed: latin name Hedysari Radix, taste is pungent, warm in nature, returns spleen, lung channel, has eliminating dampness in temperature, and eliminating dampness is loose cold, and the effect of being amusing and helping digestion cures mainly the cards such as coldness and pain in the epigastrium, dyspepsia turgor, vomiting are had loose bowels, drinking too much.
Galangal: taste is pungent, hot in nature, return spleen, stomach warp, there is warming stomach for dispelling cold, the effect of the pain relieving that helps digestion.For coldness and pain in the epigastrium, gastrofrigid vomiting, the cards such as belch acid regurgitation.
Sea-buckthorn: latin name Hippophae Fructus, taste acid; Puckery; Warm in nature, have relieving cough and reducing sputum; Stomach strengthening and digestion promoting; The effect of promoting blood circulation to remove blood stasis.Cure mainly coughing with a lot of sputum; Pulmonary abscess; Indigestion; Dyspeptic abdominalgia; Stomachache; Enteritis; Amenorrhoea; Fall and beat the swollen card that waits of the stasis of blood.
Asafoetide: bitter, pungent, warm in nature, return kidney, stomach warp, have disappear long-pending, loose ruffian, the effect of desinsection, stagnant for meat, hemostasis abdominal mass, mass in abdomen, the cards such as abdominal pain due to enterositosis.
The membrane of a chicken's gizzard: taste is sweet, cold in nature, return spleen, stomach, small intestine, urinary bladder channel, there is reinforcing spleen to promote digestion, puckery essence is stopped excessive effect, cures mainly dyspepsia turgor, vomiting gastric disorder causing nausea, rushes down dysentery, and infantile malnutrition due to digestive disturbances or intestinalparasites, quenches one's thirst, and loses and drowns, larynx numbness acute tonsillitis, the cards such as noma aphtha.
Cuttlebone: latin name Sepiae Endoconcha, taste one-tenth, puckery, warm in nature, return spleen, kidney channel, there is astringing to arrest bleeding, relieving leukorrhea by astringents, relieving gastric hyperacidity to alleviate stomachache, the effect of hygroscopic sore, cures mainly haematemesis, uterine bleeding is had blood in stool, emission and spermatorrhea, leukorrhea with reddish discharge, stomachache acid regurgitation, bleeding due to trauma, the eczema sore that wets, the cards such as unhealing ulcer.Cuttlebone composition mainly also, containing a small amount of calcium phosphate, sodium chloride and magnesium salts, has the effect of astringing to arrest bleeding and relieving haperacidity containing calcium carbonate, chitin.
The red sage root: latin name Salviae Miltiorrhizae Radix etRhizoma, bitter, cold nature, enter the heart, Liver Channel, there is promoting blood circulation for regulating menstruation, stasis-dispelling and pain-killing, the cool blood carbuncle that disappears, the relieving restlessness that clears away heart-fire, the effect of nourishing blood and tranquilization, for irregular menstruation, through closing dysmenorrhoea, a lump in the abdomen causing distension and pain, chest ventral spine pain, hot numbness pain, sore swells and ache, dysphoria and insomnia; Hepatosplenomegaly, the cards such as angina pectoris.
East wind dish: taste is pungent, sweet, cold in nature, has loose wind-heat, and refresh oneself's effect, cures mainly headache due to pathogenic wind-heat, dizzy, hot eyes, pharyngalgia, the cards such as snake bite.
Meadow pine: taste is sweet, bitter, cool in nature, returns lung, Liver Channel, has the effect of hemostasis, cough-relieving, diuresis, improving eyesight, cures mainly haematemesis, and hemoptysis, has blood in stool, uterine bleeding, traumatism and bleeding, cough and asthma, the cards such as stranguria.
Cymbopogon distans: pungent, the micro-hardship of taste, warm in nature, there is expelling pathogen from the exterior and eliminating dampness by diuresis, relieving cough and asthma effect, cures mainly anemofrigid cold, hinders heat, the stomachache of vomiting and diarrhoea, urine leaching pain, arthralgia due to wind-dampness, the cards such as cough and asthma.
Further, described Chinese herbal feed additive only consists of above-mentioned raw materials medicine.
In described Chinese herbal feed additive, the weight portion of each bulk drug is respectively barrenwort 60 weight portion~70 weight portions, eclipta 30 weight portion~40 weight portions, the stem of noble dendrobium 25 weight portion~35 weight portions, the Radix Astragali 50 weight portion~60 weight portions, gypsum 45 weight portion~55 weight portions, wilsonii 35 weight portion~45 weight portions, the vine of multiflower knotweed 20 weight portion~30 weight portions, cape jasmine 15 weight portion~25 weight portions, Radix Liriopes 20 weight portion~30 weight portions, Psoralea corylifolia 35 weight portion~45 weight portions, Semen sesami nigrum 20 weight portion~30 weight portions, thizoma curculiginis 25 weight portion~35 weight portions, parasitic loranthus 15 weight portion~25 weight portions, Chinese yam 25 weight portion~35 weight portions, Common St.Paulswort Herb 20 weight portion~30 weight portions, Galanga Galangal Seed 25 weight portion~35 weight portions, galangal 20 weight portion~30 weight portions, sea-buckthorn 25 weight portion~35 weight portions, asafoetide 20 weight portion~30 weight portions, the membrane of a chicken's gizzard 25 weight portion~35 weight portions, cuttlebone 30 weight portion~40 weight portions, the red sage root 25 weight portion~35 weight portions, east wind dish 25 weight portion~35 weight portions, meadow pine 20 weight portion~30 weight portions and cymbopogon distans 25 weight portion~35 weight portions.
Further preferably, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively barrenwort 63 weight portion~67 weight portions, eclipta 33 weight portion~37 weight portions, the stem of noble dendrobium 28 weight portion~32 weight portions, the Radix Astragali 53 weight portion~57 weight portions, gypsum 48 weight portion~52 weight portions, wilsonii 38 weight portion~42 weight portions, the vine of multiflower knotweed 23 weight portion~27 weight portions, cape jasmine 18 weight portion~22 weight portions, Radix Liriopes 23 weight portion~27 weight portions, Psoralea corylifolia 38 weight portion~42 weight portions, Semen sesami nigrum 23 weight portion~27 weight portions, thizoma curculiginis 28 weight portion~32 weight portions, parasitic loranthus 18 weight portion~22 weight portions, Chinese yam 28 weight portion~32 weight portions, Common St.Paulswort Herb 23 weight portion~27 weight portions, Galanga Galangal Seed 28 weight portion~32 weight portions, galangal 23 weight portion~27 weight portions, sea-buckthorn 28 weight portion~32 weight portions, asafoetide 23 weight portion~27 weight portions, the membrane of a chicken's gizzard 28 weight portion~32 weight portions, cuttlebone 33 weight portion~37 weight portions, the red sage root 28 weight portion~32 weight portions, east wind dish 28 weight portion~32 weight portions, meadow pine 23 weight portion~27 weight portions and cymbopogon distans 28 weight portion~32 weight portions.
Most preferably, in described Chinese herbal feed additive, the weight portion of each bulk drug is respectively barrenwort 65 weight portions, eclipta 35 weight portions, the stem of noble dendrobium 30 weight portions, the Radix Astragali 55 weight portions, gypsum 50 weight portions, wilsonii 40 weight portions, the vine of multiflower knotweed 25 weight portions, cape jasmine 20 weight portions, Radix Liriopes 25 weight portions, Psoralea corylifolia 40 weight portions, Semen sesami nigrum 25 weight portions, thizoma curculiginis 30 weight portions, parasitic loranthus 20 weight portions, Chinese yam 30 weight portions, Common St.Paulswort Herb 25 weight portions, Galanga Galangal Seed 30 weight portions, galangal 25 weight portions, sea-buckthorn 30 weight portions, asafoetide 25 weight portions, the membrane of a chicken's gizzard 30 weight portions, cuttlebone 35 weight portions, the red sage root 30 weight portions, east wind dish 30 weight portions, meadow pine 25 weight portions and cymbopogon distans 30 weight portions.
The present invention also provides the preparation method of above-mentioned Chinese herbal feed additive, is specially:
Above-mentioned raw materials medicine component is mixed by weight, obtain mixture, put into reactor, add the water with respect to 3~5 times of mixture qualities, slow fire heating decocts 2~4 hours, and decoction liquor is filtered, filter residue adds the water with respect to 2~4 times of the mixture qualities obtaining above, and slow fire boiling is 1~3 hour again, and decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive.
The present invention also provides the preparation method of above-mentioned feed, and it comprises:
The first step, get 3kg microbe additive and join in 100kg~120kg water and mix, obtain zymotic fluid, the zymotic fluid that 100kg is obtained joins in 100kg main feed composition, evenly pack sealing, is placed in the environment of 20 ℃~30 ℃ and obtains fermentation material after 10~20 days;
Second step, prepares Chinese herbal feed additive according to the method described above;
The 3rd step, together with the Chinese herbal feed additive that the fermentation material that the first step is obtained obtains with second step and other components, put into fodder mixing machine, continuous uniform stirred after 1~3 hour, putting into pulverizer tentatively pulverizes, after taking-up, putting into micronizer, to carry out separating twice be fine grained again, the feed that gets product after sterilization, sealing, pack of the fine grained after pulverizing.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
Embodiment 1 Chinese medicine composition feed addictive 1
By barrenwort 65g, eclipta 35g, stem of noble dendrobium 30g, Radix Astragali 55g, gypsum 50g, wilsonii 40g, vine of multiflower knotweed 25g, cape jasmine 20g, Radix Liriopes 25g, Psoralea corylifolia 40g, Semen sesami nigrum 25g, thizoma curculiginis 30g, parasitic loranthus 20g, Chinese yam 30g, Common St.Paulswort Herb 25g, Galanga Galangal Seed 30g, galangal 25g, sea-buckthorn 30g, asafoetide 25g, the membrane of a chicken's gizzard 30g, cuttlebone 35g, red sage root 30g, east wind dish 30g, meadow pine 25g and cymbopogon distans 30g mix, obtain mixture, put into reactor, the water that adds 3.5kg, slow fire heating decocts 3 hours, decoction liquor is filtered, filter residue adds the water of 2.5kg, slow fire boiling is 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 1.
Embodiment 2 Chinese medicine composition feed addictives 2
By barrenwort 63g, eclipta 33g, stem of noble dendrobium 28g, Radix Astragali 53g, gypsum 48g, wilsonii 38g, vine of multiflower knotweed 23g, cape jasmine 18g, Radix Liriopes 23g, Psoralea corylifolia 38g, Semen sesami nigrum 23g, thizoma curculiginis 28g, parasitic loranthus 18g, Chinese yam 28g, Common St.Paulswort Herb 23g, Galanga Galangal Seed 28g, galangal 23g, sea-buckthorn 28g, asafoetide 23g, the membrane of a chicken's gizzard 28g, cuttlebone 33g, red sage root 28g, east wind dish 28g, meadow pine 23g and cymbopogon distans 28g mix, obtain mixture, put into reactor, the water that adds 3.5kg, slow fire heating decocts 3 hours, decoction liquor is filtered, filter residue adds the water of 2.5kg, slow fire boiling is 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 2.
Embodiment 3 Chinese medicine composition feed addictives 3
By barrenwort 67g, eclipta 37g, stem of noble dendrobium 32g, Radix Astragali 57g, gypsum 52g, wilsonii 42g, vine of multiflower knotweed 27g, cape jasmine 22g, Radix Liriopes 27g, Psoralea corylifolia 42g, Semen sesami nigrum 27g, thizoma curculiginis 32g, parasitic loranthus 22g, Chinese yam 32g, Common St.Paulswort Herb 27g, Galanga Galangal Seed 32g, galangal 27g, sea-buckthorn 32g, asafoetide 25g, the membrane of a chicken's gizzard 30g, cuttlebone 35g, red sage root 30g, east wind dish 30g, meadow pine 25g and cymbopogon distans 30g mix, obtain mixture, put into reactor, the water that adds 3.5kg, slow fire heating decocts 3 hours, decoction liquor is filtered, filter residue adds the water of 2.5kg, slow fire boiling is 2 hours again, decoction liquor is filtered again, filtered fluid is merged, concentrated except anhydrating, obtain lotion, dry, pulverize, obtain Chinese herbal feed additive 3.
Embodiment 4 pharmacology toxicity tests
Acute toxicity test data
Detect reagent
Serum AST, ALT detection kit are purchased from Rui Sheng bio tech ltd, Qingdao.
Checkout equipment
Micro-200 semiautomatic biochemistry detector, assay balance, disscting instrument, syringe, test tube etc.
Test method
After the adaptability of 3 days are raised, be divided at random 4 groups (male and female half and half), every group each 20; Control group, 3 different pharmaceutical groups (are respectively 300g/kg body weight, 240g/kg body weight, 180g/kg body weight), control group gavage physiological saline, the Chinese herbal feed additives 1 of 3 medicine group gavage embodiment of the present invention, 1 preparation, are dissolved in Chinese herbal feed additive in water, to gavage mouse.
Testing index and method
(1) clinicing symptom observation: every day viewing test mouse the state of mind, diet situation, every day entry Mortality situation.
(2) pathological observation: cut open inspection for dead mouse and observe internal organ variation.
(3) growth indexes is observed: test mouse is carried out to routine weighing; Off-test, slaughters that mouse weighs in, the heavy organ index of internal organs measures: cut open inspection rat, dirty, the spleen of coring, liver, kidney, testis, ovary, weigh, and calculates according to the following formula organ index: organ index=internal organs weight/body weight * 100.
(4) liver function changes observation: after off-test, slaughter mouse, take blood separation of serum, measure AST, ALT.
Data processing and analysis
Each is organized data and all uses mean soil standard deviation
represent, each is organized mean and does test of normality and duplicate measurements homogeneity test of variance, younger check between organizing with one-way analysis of variance), P < 0.05 is for differing significantly, and P < 0.01 is for differing highly significant.Statistical computation all adopts SPSS12.0 software to complete.
Clinicing symptom observation
Control group and test group mouse, the state of mind and diet are wanted, respond has no significantly abnormal to external world.Each organizes mouse morbidity and death condition as following table 1.
Table 1
Grouping |
Sum |
Dead (only) |
The death rate (%) |
1(300g/kg) |
20 |
0 |
0 |
2(240g/kg) |
20 |
0 |
0 |
3(120g/kg) |
20 |
0 |
0 |
Control group |
20 |
0 |
0 |
Pathological observation: control group and test group, mouse is cutd open after slaughtering to examine to observe to have no and observes the obvious pathological change of internal organs.
Growth indexes is observed: off-test, slaughter that mouse weighs in, internal organs weight analysis is in Table 2.
Table 2
Grouping |
Liver index |
Cardiac index |
Renal index |
Lungs index |
Index and spleen index |
1(300g/kg) |
5.77±0.41 |
0.79±0.05 |
1.33±0.27 |
0.72±0.03 |
0.52±0.06 |
2(240g/kg) |
5.69±0.33 |
0.82±0.03 |
1.30±0.26 |
0.69±0.05 |
0.49±0.03 |
3(120g/kg) |
5.72±0.39 |
0.76±0.06 |
1.32±0.21 |
0.73±0.07 |
0.55±0.04 |
Control group |
5.70±0.31 |
0.79±0.06 |
1.30±0.17 |
0.69±0.11 |
0.53±0.07 |
Liver function changes to be observed
After off-test, slaughter mouse, take blood separation of serum, measure AST (glutamic-oxalacetic transaminease), ALT (glutamic-pyruvic transaminase) in Table 3.Result shows respectively to be organized data and normal healthy controls group to compare difference not remarkable, all in normal range (NR).
Table 3
Grouping |
Sum |
ALT |
AST |
1(300g/kg) |
20 |
31.62±2.72 |
130.59±6.29 |
2(240g/kg) |
20 |
32.16±2.49 |
133.27±8.11 |
3(120g/kg) |
20 |
31.78±3.15 |
132.93±9.63 |
Control group |
20 |
33.27±3.26 |
131.26±14.11 |
Long term toxicity test data
According to the Chinese herbal feed additive 10g/kg of the present invention of embodiment 1 preparation, 20g/kg, 100g/kg to the continuous gastric infusion of rat 3 months, the fur of animal, the colour of skin, ingest, movable, urine, just etc. all without the main organs index of the blood parameters such as the routine blood test of animal extremely, liver, renal function and animal all in normal range (NR), and normally power indifference histopathologic examination shows, the important organs such as the heart, liver, spleen, lung, kidney, adrenal gland, tracheae, testis, ovary are without pathological change.Drug withdrawal checks after two weeks that above indices, all without overt toxicity reaction, shows without cumulative toxicity.
Embodiment 5 feeds 1
Getting 3kg microbe additive source health precious (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides) joins in 100kg water and mixes, obtain zymotic fluid, the zymotic fluid that 100kg is obtained joins 80kg corn, in the main feed composition that 15kg wheat bran and 5kg dregs of beans form, evenly pack sealing, be placed in the environment of 25 ℃ and obtain fermentation material after 15 days, by Chinese herbal feed additive 16kg and soybean lecithin (source, Beijing magnificent phosphatide Science and Technology Ltd. provides) 3kg of the fermentation material obtaining and embodiment 1 acquisition, Bee Pollen (Guangzhou Tan Shan apiculture Co., Ltd provides) 2kg, manna oligosaccharide (Wuhan Yuancheng Technology Development Co., Ltd. provides) 2kg, salt 2kg, bone meal 4kg, sodium acid carbonate 5kg, calcium carbonate 4kg, trace mineral supplement amino acid additive composite aminophenol powder (above sea cowry energy Chemical Co., Ltd. produces) 5kg, the excellent dimension element of vitamin(e) supplement (production of Beijing You Libao Bioisystech Co., Ltd) 5kg, you put into fodder mixing machine by (Beijing You Libao biotechnology Co., Ltd provides) 3kg together the Great Britain and America of trace mineral supplement, continuous uniform stirred after 3 hours, putting into pulverizer tentatively pulverizes, after taking-up, putting into micronizer, to carry out separating twice be fine grained again, fine grained after pulverizing is through sterilization, sealing, feed 1 gets product after pack.
Comparative example feed 2
Getting 3kg microbe additive source health precious (Shandong Liuhe Farming Science and Technology Park Co., Ltd provides) joins in 100kg water and mixes, obtain zymotic fluid, the zymotic fluid that 100kg is obtained joins 80kg corn, in the main feed composition that 15kg wheat bran and 5kg dregs of beans form, evenly pack sealing, be placed in the environment of 25 ℃ and obtain fermentation material after 15 days, by the fermentation material and soybean lecithin (source, Beijing magnificent phosphatide Science and Technology Ltd. provides) 3kg that obtain, Bee Pollen (Guangzhou Tan Shan apiculture Co., Ltd provides) 2kg, manna oligosaccharide (Wuhan Yuancheng Technology Development Co., Ltd. provides) 2kg, salt 2kg, bone meal 4kg, sodium acid carbonate 5kg, calcium carbonate 4kg, trace mineral supplement amino acid additive composite aminophenol powder (above sea cowry energy Chemical Co., Ltd. produces) 5kg, the excellent dimension element of vitamin(e) supplement (production of Beijing You Libao Bioisystech Co., Ltd) 5kg, you put into fodder mixing machine by (Beijing You Libao biotechnology Co., Ltd provides) 3kg together the Great Britain and America of trace mineral supplement, continuous uniform stirred after 3 hours, putting into pulverizer tentatively pulverizes, after taking-up, putting into micronizer, to carry out separating twice be fine grained again, fine grained after pulverizing is through sterilization, sealing, feed 2 gets product after pack.
Embodiment 6 effect datas
Test feed
Test group adopts the feed 1 of embodiment 5 preparations, the feed 2 that control group adopts comparative example to be prepared into.
Experimental animal and feeding and management
Experimental period 20.0~35.0 ℃ of environment temperatures, relative humidity 70%~86%, 200 540 of age in days egg-laying peak Luo Man egg kind chickens, conventional feeding and management, carries out hen house every day, tank cleans, ground, air-atomizing sterilization.
Egg Quality determining instrument
Digimatic micrometer (product type: 0.001,0-25), manufacturer: Japan three is rich.Egg Quality analyzer (product type: EMT II), manufacturer: Japanese Robot mation.Eggshell color measurement instrument (product type: QCR), manufacturer: Denmark 0VO TEC.Eggshell strength analyzer (product type: MOD EL-II), manufacturer: Japanese Robot mation.
Experimental design and method
540 Luo Man kind of chicken of laying eggs is divided into 2 processing, and each processes 3 repetitions, and each repeats 90 chickens.Test was divided into for 2 phases, preliminary trial period 7d wherein, experimental period 28d.Feed 2 prepared by control group fed comparative example, the feed feed 1 of embodiment 5 preparation of test group.
From experimental period, start every day regularly by each duplicate record egg number, egg size and superseded egg quantity, calculate average egg production, average egg weight and kind egg mortality.After off-test, each repeated acquisition kind egg is 2~3 pieces, amounts to 127 pieces.
Result
The impact of Chinese herbal feed additive on laying rate of laying hen, the results are shown in Table 4.
The impact of table 4 Chinese herbal feed additive on laying rate of laying hen
As can be seen from Table 4, adopt Chinese herbal feed additive laying rate of laying hen provided by the invention As time goes on, significant variation do not occur, and be slightly improved, and control group reduces significantly, both significant differences, P < 0.05.
The impact of planting egg mortality, the results are shown in Table 5.
The impact of table 5 kind of egg mortality
As can be seen from Table 5, adopt Chinese herbal feed additive provided by the invention As time goes on,
Plant egg mortality and significantly reduce, with control group significant difference, P < 0.05.
The impact of egg kind chicken average egg weight, the results are shown in Table 6.
The impact of table 6 egg kind chicken average egg weight
As can be seen from Table 6, adopt Chinese herbal feed additive provided by the invention can significantly improve egg size, with control group significant difference, P < 0.05.
The impact of Egg Quality, the results are shown in Table 7.
The impact of table 7 Egg Quality
As can be seen from Table 7, adopt Chinese herbal feed additive provided by the invention can significantly improve hangh unit, albumen height and the eggshell strength of egg, compare with control group, significant difference, P < 0.05, and on shell thickness and eggshell color and luster impact impact, test group and control group be without significant difference, P > 0.05.
All above-mentioned these intellectual properties of primary enforcement, do not set restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above, be only preferred embodiment of the present invention, is not the present invention to be done to the restriction of other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.