CN103585552A - Preparation method of medicine for treating summer fever of children - Google Patents
Preparation method of medicine for treating summer fever of children Download PDFInfo
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- CN103585552A CN103585552A CN201310595250.XA CN201310595250A CN103585552A CN 103585552 A CN103585552 A CN 103585552A CN 201310595250 A CN201310595250 A CN 201310595250A CN 103585552 A CN103585552 A CN 103585552A
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- 239000003814 drug Substances 0.000 title claims abstract description 22
- 206010037660 Pyrexia Diseases 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 230000001954 sterilising effect Effects 0.000 claims abstract description 10
- 239000002994 raw material Substances 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 6
- 239000011521 glass Substances 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 3
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 3
- 229940079593 drug Drugs 0.000 claims description 3
- 238000005538 encapsulation Methods 0.000 claims description 3
- 210000003038 endothelium Anatomy 0.000 claims description 3
- 238000002386 leaching Methods 0.000 claims description 3
- 239000010271 massa medicata fermentata Substances 0.000 claims description 3
- 238000007789 sealing Methods 0.000 claims description 3
- 244000080767 Areca catechu Species 0.000 claims description 2
- 235000009604 Chrysanthemum X morifolium Nutrition 0.000 claims description 2
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims description 2
- 210000004072 lung Anatomy 0.000 abstract description 11
- 210000002784 stomach Anatomy 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 6
- 210000003734 kidney Anatomy 0.000 abstract description 3
- 230000035922 thirst Effects 0.000 abstract description 2
- 238000010792 warming Methods 0.000 abstract description 2
- 235000019606 astringent taste Nutrition 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 231100000957 no side effect Toxicity 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 210000003296 saliva Anatomy 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 description 9
- 201000010099 disease Diseases 0.000 description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 9
- 208000004880 Polyuria Diseases 0.000 description 7
- 210000001124 body fluid Anatomy 0.000 description 7
- 239000010839 body fluid Substances 0.000 description 7
- 208000037920 primary disease Diseases 0.000 description 6
- 206010036067 polydipsia Diseases 0.000 description 5
- 230000006735 deficit Effects 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 208000008017 Hypohidrosis Diseases 0.000 description 3
- 230000027939 micturition Effects 0.000 description 3
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- 238000003745 diagnosis Methods 0.000 description 2
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- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 206010024264 Lethargy Diseases 0.000 description 1
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- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a preparation method of a medicine for treating summer fever of children. According to the preparation method, the medicine is prepared from the raw materials of traditional Chinese medicines through the steps of decocting, sterilizing, packaging and the like. The medicine provided by the invention focuses on the effects of clearing lung and stomach and removing internal heat, meanwhile has the effects of helping qi of middle-jiao energy and nourishing lung and stomach, and further has the effects of warming kidney yang, clearing heart fire, inducing astringency, helping produce saliva and slaking thirst. The medicine can warm purgation and clear upper part, has a very good effect for treating the summer fever of children, and has no side effects.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specially a kind of preparation method for the treatment of Infantile Summer Fever medicine.
Background technology
Summer fever is the infant a kind of peculiar disease in period.It is clinical that to take summer has set in long-term fever, thirsty polydipsia, polyuria, perspiration stagnation be feature.Because primary disease has strict seasonality, fallen ill summer, therefore named summer fever.Western medicine claims febrile disease due to summer-heat pathogen.
Primary disease mainly betides south China, as the southeast, the hot climate such as Central-South and southwestern area.5 years old following children's is more common in morbidity.Disease time was focused mostly in 6,7,8 three months, had substantial connection with weather, and temperature is higher, and morbidity is outstanding many, but after cool autumn days, symptom multipotency disappears voluntarily.Some sick children can fall ill for several years running, and along with the age increases, its disease symptom can alleviate year by year, and the course of disease is also shorter.If primary disease is without other complication, prognosis belongs to good.
Pathogenic factor is main relevant with children's's physical factors.Have because children's's natural endowment is not enough, as premature infant, premature infant, deficiency of kidney-QI person; Have because of the taste deficiency day after tomorrow, development nutrition is poor, weakness of the spleen and stomach person; Have because body is empty after being ill, deficiency of both vital energy and Yin person, people can not tolerate the stifling of summer-heat weather after the summer, easily suffer from primary disease.The characteristic of summer-heat being scorching, easily consumes impairment of body fluid liquid.Children's emits and is subject to summer heat, accumulates in lung stomach, Tianjin of the lung stomach of burning, body fluid deficiency interior-heat is flourishing, thus heating, thirsty polydipsia; Summer-heat is easily felt frustrated again, collapse of QI, and QI failing to transform into body fluid, the bladder that becomes under water liquid, and occur that frequent micturition is long clearly; Lung Tianjin is hindered by summer-heat again, and lung master is respectful clearly, closes fur space between skin and muscles outward, department's folding, functional activities of the body fluid two loses,, insufficient water sources, water liquid is difficult compress, space between skin and muscles is inaccessible, therefore see hypohidrosis or perspiration stagnation; Antiperspirant and urine, all belong to cloudy Tianjin, foreign body and homology, so perspiration stagnation frequent micturition, frequent micturition Tianjin Shang， Tianjin wound must be drunk water and saved oneself, thereby forms the syndrome of perspiration stagnation, thirsty polydipsia, polyuria.According to features such as the easy impairment of body fluid of summer-heat, consumption gas, folder are wet, and children's's body reports and has lung stomach-Yin to lose or the factor such as deficiency of spleen-YANG and kidneyYANG, and therefore in the generation of disease and development, its pathogenesis is had nothing in common with each other with lapsing to.Disease from the beginning of, the many impairment of body fluid of summer-heat are felt frustrated, and are prone to lung stomach impairment of both QI and YIN card; Disease delay, or plain body weakness of the spleen and kidney, outward for summer heat is stifling, inside insufficiency of kidney-YANG, is prone to heat excessive in upper, yang deficiency under " upper excess and lower deficiency " demonstrate,prove.
Though primary disease betides summer, as none, pathogenic summer-heat is caused a disease and people seeks human blood, the change of disease rule of the conscience of caving in.Primary disease causes for " summer heat stifling ", many without acute variation, and to oriented machine of healing after cool autumn days, but touching with the passing of time person also can affect children's's body constitution.
Summary of the invention
The object of the invention is, in order to overcome above-mentioned the deficiencies in the prior art part, provides a kind of preparation method for the treatment of Infantile Summer Fever medicine according to Chinese medical theory.
The preparation method that the present invention treats Infantile Summer Fever medicine comprises the following steps:
The first step: get by weight 10 parts of crude drug Cortex Magnoliae Officinalis, 6 parts of Pericarpium Citri Reticulataes, 6 parts of Massa Medicata Fermentata, 6 parts of the Radix Aucklandiae, 20 parts of Fructus Crataegi (parched to brown)s, 10 parts of Semen Arecaes, fry each 30 parts of two buds, 10 parts of Endothelium corneum, 6 parts of Fructus Amomis, 30 parts of Gypsum Fibrosum, 10 parts of Cortex Lycii, 10 parts of Herba Dendrobiis, 10 parts of Fructus Mumes, 10 parts of Semen Raphanis, 10 parts of Plumula Nelumbiniss and 10 parts, Poria are standby;
Second step: after above-mentioned raw materials medicine is mixed, soak, amount of water is 10 times of medicine gross weight, and soak time is 1 hour;
The 3rd step: soak and be first heated to 71～80 degree after 1 hour and decoct 20 minutes, then heat to 95～100 degree and decoct 30 minutes, be then cooled to 60～70 degree and decoct and cross leaching filtrate after 40 minutes;
The 4th step: pack above-mentioned filtrate into glass jar and add a cover pre-packagedly, then send into fumer, keep 16～20 minutes, make glass jar temperature reach 70 degree, then encapsulation.
The 5th step: sterilize after sealing, make sterilization temperature reach 100 degree, sterilizing time 35-40 second, be cooled to 37 degree after sterilization below.
The present invention focuses on lung heat clearing stomach, lets out interior-heat, takes into account simultaneously and helps middle gas, supports lung stomach; But also the kidney warming is positive, clearing away heart-fire, astringent or styptic treatment for spontaneous sweating promoting the production of body fluid to quench thirst, the effect of the lower clear upper treatment Infantile Summer Fever of temperature is very good, and without any side effects.
The specific embodiment
A kind of preparation method of Infantile Summer Fever medicine comprises the following steps:
The first step: get by weight crude drug Cortex Magnoliae Officinalis 10g, Pericarpium Citri Reticulatae 6g, Massa Medicata Fermentata 6g, Radix Aucklandiae 6g, Fructus Crataegi (parched to brown) 20g, Semen Arecae 10g, fries each 30g of two buds, Endothelium corneum 10g, Fructus Amomi 6g, Gypsum Fibrosum 30g, Cortex Lycii 10g, Herba Dendrobii 10g, Fructus Mume 10g, Semen Raphani 10g, Plumula Nelumbinis 10g and Poria 10g are standby;
Second step: after above-mentioned raw materials medicine is mixed, soak, amount of water is 10 times of medicine gross weight, and soak time is 1 hour;
The 3rd step: soak and be first heated to 71～80 degree after 1 hour and decoct 20 minutes, then heat to 95～100 degree and decoct 30 minutes, be then cooled to 60～70 degree and decoct and cross leaching filtrate after 40 minutes;
The 4th step: pack above-mentioned filtrate into glass jar and add a cover pre-packagedly, then send into fumer, keep 16～20 minutes, make glass jar temperature reach 70 degree, then encapsulation.
The 5th step: sterilize after sealing, make sterilization temperature reach 100 degree, sterilizing time 35-40 second, be cooled to 37 degree after sterilization below.
Diagnosis basis:
Be more common in the weak child of 2～5 years old.Morbidity in summer, sickness rate raises and increases with temperature.Be more common in south China area.After summer has set in, long-term fever, with the thirsty polydipsia of door, polyuria, lossless or hypohidrosis.With temperature, reduce or energy spontaneous remission under shady and cool environment.Physical examination and the normal Non Apparent Abnormality of experiment word inspection.
Syndrome-classification:
Summer-heat impairing the lung stomach: heating, thirsty, polyuria, lossless or hypohidrosis, dysphoria, lip extra dry red wine.Red tongue, white and thin fur or BOHUANG, rapid pulse.
Upper excess and lower deficiency: heating, thirsty polydipsia, polyuria time frequency, perspiration stagnation, lethargy, fidgets due to deficiency is uneasy, pale white complexion, lower limb are owed temperature, and stomach poor appetite moves back, or it is thin to defecate.Pale tongue, tongue book, thready and rapid pulse.
Clinical trial:
According to above-mentioned diagnosis basis, choose 100 routine infants, 2～5 years old age, medicinal liquid 10～20mg that oral embodiment makes, every day 3～4 times, take 15～30 minutes ante cibum, within 7 days, is a course for the treatment of, takes continuously 2 courses for the treatment of.Then carry out clinical observation.
Efficacy assessment standard is as follows:
1. cure: body temperature is normal, thirsty, the transference cures such as polyuria.
2. take a turn for the better: the symptoms such as heating alleviates, thirsty, polyuria are improved.
3. do not heal: symptom is unchanged.
Period in a medicine clinical observation on the therapeutic effect analysis result is as follows:
| Criterion of therapeutical effect | Treatment group number of cases | Percentage rate (%) |
| Cure | 81 | 81% |
| Take a turn for the better | 14 | 14% |
| Do not heal | 5 | 5% |
Total effective rate 95% as can be seen from the above table.
Claims (1)
1. treat a preparation method for Infantile Summer Fever medicine, it is characterized in that comprising the steps:
The first step: get by weight 10 parts of crude drug Cortex Magnoliae Officinalis, 6 parts of Pericarpium Citri Reticulataes, 6 parts of Massa Medicata Fermentata, 6 parts of the Radix Aucklandiae, 20 parts of Fructus Crataegi (parched to brown)s, 10 parts of Semen Arecaes, fry each 30 parts of two buds, 10 parts of Endothelium corneum, 6 parts of Fructus Amomis, 30 parts of Gypsum Fibrosum, 10 parts of Cortex Lycii, 10 parts of Herba Dendrobiis, 10 parts of Fructus Mumes, 10 parts of Semen Raphanis, 10 parts of Plumula Nelumbiniss and 10 parts, Poria are standby;
Second step: after above-mentioned raw materials medicine is mixed, soak, amount of water is 10 times of medicine gross weight, and soak time is 1 hour;
The 3rd step: soak and be first heated to 71～80 degree after 1 hour and decoct 20 minutes, then heat to 95～100 degree and decoct 30 minutes, be then cooled to 60～70 degree and decoct and cross leaching filtrate after 40 minutes;
The 4th step: pack above-mentioned filtrate into glass jar and add a cover pre-packagedly, then send into fumer, keep 16～20 minutes, make glass jar temperature reach 70 degree, then encapsulation.
The 5th step: sterilize after sealing, make sterilization temperature reach 100 degree, sterilizing time 35-40 second, be cooled to 37 degree after sterilization below.
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| CN201310595250.XA CN103585552B (en) | 2013-11-22 | 2013-11-22 | The preparation method for the treatment of Infantile Summer Fever medicine |
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| CN201310595250.XA CN103585552B (en) | 2013-11-22 | 2013-11-22 | The preparation method for the treatment of Infantile Summer Fever medicine |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101450140A (en) * | 2007-11-30 | 2009-06-10 | 曾雄辉 | Preparation method of schizonepetae and forsythia decoction |
| CN101961464A (en) * | 2010-04-27 | 2011-02-02 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating jaundice and preparation method thereof |
| CN102366473A (en) * | 2011-11-07 | 2012-03-07 | 齐鲁动物保健品有限公司 | Oral traditional Chinese medicine preparation for treating swine high fever disease and preparation method thereof |
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2013
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101450140A (en) * | 2007-11-30 | 2009-06-10 | 曾雄辉 | Preparation method of schizonepetae and forsythia decoction |
| CN101961464A (en) * | 2010-04-27 | 2011-02-02 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating jaundice and preparation method thereof |
| CN102366473A (en) * | 2011-11-07 | 2012-03-07 | 齐鲁动物保健品有限公司 | Oral traditional Chinese medicine preparation for treating swine high fever disease and preparation method thereof |
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| CN103585552B (en) | 2015-12-09 |
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Inventor after: Zhang Zhihong Inventor after: Zhu Xibin Inventor before: The inventor has waived the right to be mentioned |
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Effective date of registration: 20170228 Address after: 075100 Hebei District, Xuanhua, Chaoyang Street, Lane seven, Lane 23, unit 1, unit 402, No. Patentee after: Zhang Zhihong Patentee after: Zhu Xibin Address before: 430000 Hubei city of Wuhan province Optics Valley East Lake New Technology Development Zone, Road No. 58 South Fuxing garden of medicine of 4 7 storey building No. 02 Patentee before: Wuhan Hong Xintong Science and Technology Ltd. |
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Granted publication date: 20151209 Termination date: 20171122 |