CN103585347B - Chinese medicinal composition for treating burns and scalds and preparation method thereof - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating burns and scalds. The Chinese medicinal composition is composed of, by mass: 3-5 parts of propolis, 0.5-1 part of borneol, 5-15 parts of phellodendron, 10-20 parts of beeswax, 5-10 parts of Sanguisorba officinalis, 5-10 parts of radix rehmanniae, 5-10 parts of Rhizoma Coptidis, 5-10 parts of rhubarb, 5-10 parts of Scutellaria baicalensis, 1-3 parts of lithospermum, and 450-550 parts of sesame oil. The preparation method of the Chinese medicinal composition includes: grinding borneol, radix rehmanniae, Rhizoma Coptidis, and lithospermum into a fine powder respectively, and sieving the powder by a sieve of 80-120 meshes for standby use; putting sesame oil and beeswax into a pot, conducting heating and stirring simultaneously, and after melting of the beeswax, performing cooling to 70-80DEG C, adding borneol, further conducting cooling to 40-50DEG C, adding the residual components, stirring the mixture uniformly, thus obtaining a thick paste or paste. The Chinese medicinal composition provided by the invention solves the problems of long treatment cycle and slow effect in existing ointments for treating burns and scalds, has the effects of clearing away heat and toxic materials, removing necrotic tissues and promoting granulation, relieving pain, promoting blood circulation and removing blood stasis, and can effectively prevent infection and inhibit scar hyperplasia.

Description

A kind of Chinese medicine composition for the treatment of burn and scald and preparation method thereof

Technical field

The invention belongs to Chinese drug preparation technique field, be specifically related to a kind of Chinese medicine composition for the treatment of burn and scald, the invention still further relates to the preparation method of this Chinese medicine composition.

Background technology

In daily life, people often can because of being scalded by boiled water or steam because of carelessness, by the situation of the burn and scald such as fire burn, for burn and scald patient, maximum misery be exactly having an intense pain of wound surface.Scald for I degree and light degree Ⅱ, can rush with Aloe and cold water, cool pain-alleviating, generally can treat at home, smears general burn cream.And for dark II degree or Superficial third degree burn, the process of wound surface is particularly important, treat dark II degree or Superficial third degree burn wound surface, often because the factors such as infection cause local damage to increase the weight of, the remaining epithelial distortion even making it parabiosis region is downright bad, finally worsen as deep third degree patient, or cause scar hyperplasia to bring larger misery to patient.Although treatment burn, the ointment of scalding are a lot, but ubiquity that treatment cycle is long, slow, the easy infection of taking effect, easily stay the shortcomings such as cicatrix, brings misery to patient.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine composition for the treatment of burn and scald, solve the medicinal ointment therapy cycle length of existing treatment burn and scald, take effect slow problem.

Another object of the present invention is to provide the preparation method of above-mentioned Chinese medicine composition.

The technical solution adopted in the present invention is: a kind of Chinese medicine composition for the treatment of burn and scald, be made up of following component by mass fraction: propolis 3-5 part, Borneolum Syntheticum 0.5-1 part, Cortex Phellodendri 5-15 part, Cera Flava 10-20 part, Radix Sanguisorbae 5-10 part, Radix Rehmanniae 5-10 part, Rhizoma Coptidis 5-10 part, Radix Et Rhizoma Rhei 5-10 part, Radix Scutellariae 5-10 part, Radix Arnebiae (Radix Lithospermi) 1-3 part, Oleum Sesami 450-550 part.

Another technical scheme of the present invention is that the preparation method of above-mentioned Chinese medicine composition, comprises the following steps:

Step 1,

Each raw material is taken: propolis 3-5 part, Borneolum Syntheticum 0.5-1 part, Cortex Phellodendri 5-15 part, Cera Flava 10-20 part, Radix Sanguisorbae 5-10 part, Radix Rehmanniae 5-10 part, Rhizoma Coptidis 5-10 part, Radix Et Rhizoma Rhei 5-10 part, Radix Scutellariae 5-10 part, Radix Arnebiae (Radix Lithospermi) 1-3 part, Oleum Sesami 450-550 part according to following mass fraction;

Step 2,

Borneolum Syntheticum, the Radix Rehmanniae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi) are ground into fine powder respectively, cross 80-120 mesh sieve, for subsequent use;

Step 3,

Oleum Sesami and Cera Flava are put into pot heat while stirring, after Cera Flava melts, stop heating, cooling adds Borneolum Syntheticum, add propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Et Rhizoma Rhei after continuing cooling, be fully uniformly mixed, make thick paste or paste.

Feature of the present invention is also,

The temperature adding Borneolum Syntheticum in step 3 is 70-80 DEG C.

Add in step 3 propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Et Rhizoma Rhei temperature be 40-50 DEG C.

The invention has the beneficial effects as follows: a kind of Chinese medicine composition for the treatment of burn and scald of the present invention and preparation method thereof, solve the medicinal ointment therapy cycle length of existing treatment burn and scald, take effect slow problem, add the important compositions such as propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi), there is heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation, pain relieving, function of promoting blood circulation to disperse blood clots, alleviate the misery of patient; Protection wound surface, pathogenic bacteria cannot Growth and reproduction, can effective prevention infection; There is the very strong ability penetrating crust and eschar, accelerate SD-Ag Cream ability, suppress scar hyperplasia, shorten recovery time, shorten the course for the treatment of; Alleviate the financial burden of patient, this medicine is nontoxic, harmless, medicine source is abundant, cost is low.

Detailed description of the invention

Below in conjunction with detailed description of the invention, the present invention is described in detail.

One, the prescription of Chinese medicine composition of the present invention and content

A kind of Chinese medicine composition for the treatment of burn and scald of the present invention, be made up of following component by mass fraction: propolis 3-5 part, Borneolum Syntheticum 0.5-1 part, Cortex Phellodendri 5-15 part, Cera Flava 10-20 part, Radix Sanguisorbae 5-10 part, Radix Rehmanniae 5-10 part, Rhizoma Coptidis 5-10 part, Radix Et Rhizoma Rhei 5-10 part, Radix Scutellariae 5-10 part, Radix Arnebiae (Radix Lithospermi) 1-3 part, Oleum Sesami 450-550 part.

The preparation method of above-mentioned Chinese medicine composition, comprises the following steps:

Step 1,

Each raw material is taken: propolis 3-5 part, Borneolum Syntheticum 0.5-1 part, Cortex Phellodendri 5-15 part, Cera Flava 10-20 part, Radix Sanguisorbae 5-10 part, Radix Rehmanniae 5-10 part, Rhizoma Coptidis 5-10 part, Radix Et Rhizoma Rhei 5-10 part, Radix Scutellariae 5-10 part, Radix Arnebiae (Radix Lithospermi) 1-3 part, Oleum Sesami 450-550 part according to following mass fraction;

Step 2,

Borneolum Syntheticum, the Radix Rehmanniae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi) are ground into fine powder respectively, cross 80-120 mesh sieve, for subsequent use;

Step 3,

Oleum Sesami and Cera Flava are put into pot heat while stirring, after Cera Flava melts, stop heating, be cooled to 70-80 DEG C and add Borneolum Syntheticum, propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Et Rhizoma Rhei is added after continuing to be cooled to 40-50 DEG C, fully be uniformly mixed, make thick paste or paste.

Two, each prescription function and function cure mainly

1, the function of each component in the present invention:

Propolis: antibacterial bacteriostatic, promotes cell regeneration; Borneolum Syntheticum: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, removing the necrotic tissue and promoting granulation; Oleum Sesami: be used for decocting ointment, has granulation promoting meat, the pain that relieves the pain, the numbness that disappears swells, mends the effect of rhagades of the skin; Three is monarch drug altogether, with reducing swelling and alleviating pain, and removing the necrotic tissue and promoting granulation;

Cortex Phellodendri: heat-clearing and toxic substances removing; Radix Sanguisorbae: heat-clearing and toxic substances removing, cooling blood and relieving pain, detumescence sore, hemostasis; The Radix Rehmanniae: clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Rhizoma Coptidis: anti-inflammatory and antalgic, antibacterial, antiulcer; Radix Et Rhizoma Rhei: removing pathogenic heat from blood and toxic substance from the body, antibacterial, infection; Radix Scutellariae: removing toxic substances, hemostasis; Six is ministerial drug altogether, plays removing toxic substances, anti-inflammation hemostasia, antibacterial effect;

Radix Arnebiae (Radix Lithospermi): removing heat from blood and promoting blood circulation, removing toxic substances is adjuvant drug;

Cera Flava: astringent therapy, sore, granulation promoting pain relieving, for making medicine; .

Full side follows the combination principle of monarch, and based on reducing swelling and alleviating pain, removing the necrotic tissue and promoting granulation, take into account anti-inflammation hemostasia, promoting blood circulation and detoxication, antibacterial bacteriostatic, make laws rigorous, hit pathogenesis.

2, function cures mainly:

A kind of Chinese medicine composition for the treatment of burn and scald of the present invention, heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation, pain relieving, blood circulation promoting and blood stasis dispelling, prevention infection, suppression scar hyperplasia, be used for the treatment of various burn, scald, burn.

3, usage:

External, ointment the present invention prepared is applied to burning, scald, the wound surface such as to burn, and keeps wound surface moistening, is coated with directly outward, wiped away by the medicine remained on intact skin, exposes wound surface.

Points for attention: 1) Oleum Sesami allergy sufferers is cautious use of; 2) need use under physician guidance the whole body biochemistry morbidity that wound surface causes; 3) high warm purgative cream is thinning does not affect the treatment.

Three, clinical observation

1, clinical collection totally 231 routine patients, 166 examples of being in hospital, outpatient service 65 example; Male 175 example, women 56 example; Age 1-5 year 48 example, 6-18 year 13 example, 19-50 year 165 example, 51-60 year 5 example.More than dark II degree of dark type 63 examples, 168 examples below dark II degree of shallow; Hot liquid scald 70 example, flame burn 158 example, other burn and scald 3 examples.

2, Therapeutic Method:

The quick diagnosis state of an illness, II degree of burn and scald injures above, and area is greater than more than 10% and wants rapid resume venous access, carries out the treatments such as dilatation, shock, infection, nutritional support; , I degree burn and scald the wounded less to area, without the need to applying antibiotic transfusion, oral antibiotic is just passable.

When carrying out Wound treatment, fully expose wound surface, hide if any medicated clothing should open gently or cut off, should avoid tearing, wipe and cause exfoliation; Pollute wound surface and can use normal saline flushing, clear the pollution off in time or pile up the beancurd sheet come off; Larger vesicle sterilization shears low level breaks, and retains bleb skin after discharging water; Deep wounds needs the ointment of in time the present invention being treated burn and scald to be uniformly coated on wound surface, thick about 1-2mm, and every day changes dressings 4-5 time, and remaining that wound surface is moistening has medicine.Wipe wound surface liquefied substance and residual ointment away with aseptic wet cotton balls when changing dressings, then smear ointment for burns and scalds of the present invention, keep moistening, until wound healing.Omnidistance medication: uninterrupted medication in therapeutic process, should not use other therapies or medicine instead halfway." three is unsuitable " principle should be followed: the unsuitable pain of wound surface, unsuitable hemorrhage, unsuitable damaging normal tissue when changing dressings.

3, criterion of therapeutical effect:

I degree of healing in empyrosis wound surface 5-8 days, without cicatrix and pigmentation; Light degree Ⅱ medication 3 days, the blackening of wound surface color, exfoliation in 6-9 days, healing in 8-12 days, preventing from scar, nonfunctional obstacle; Dark II degree of medication be after 5 days, and ooze out gradually few, within about 10 days, downright bad layer starts to loosen, downright bad layer free dropping or taken off by downright bad for small pieces layer with tweezers after 15 days, and wound surface has the graininess appendages of skin swell, within 13-18 days, heals, without cicatrix and pigmentation; The healing in about 28 days of dark II degree of dark type wound surface; III degree is healed for about the above 35-45 of burn and scald days, and part wound surface has shallow cicatrix, has pigment, but nonfunctional obstacle.

4, therapeutic outcome: 231 routine patients, all healed, nonfunctional obstacle, cure rate reaches 100%.The dark II degree of above fire victim of dark type of part has moderate to generate heat, but few high heat, without 1 routine concurrent bacterial and fungal infection.

The Chinese medicine composition that the present invention is used for the treatment of burn and scald has the following advantages:

1) relieving pain, has no stimulation to burn wound, has the effect of eliminating stasis to stop pain, removing the necrotic tissue and promoting granulation, and being applied to wounds patient has refrigerant sense, and patient's misery is rapidly disappeared, and whole body is comfortable, ataraxia, is emotionally stable;

2) fungistatic effect is obvious, after medicine is applied to wound surface, wound surface forms layer protecting film, can reduce ooze out, suppress to infect, pre-bacteriological protection, plurality of Chinese has bacteriostasis and sterilization effect, and pathogenic bacteria cannot grow, and wound surface regeneration capacity accelerates reparation;

3) there is the very strong ability penetrating crust and eschar, burn slough liquefacttus gradually from inside to outside can be made, accelerate to come off, make wound surface from inside to outside, by inner and table, by periphery to center rapid healing, accelerate the reparation of wound surface, suppress scar hyperplasia;

4) short, the instant effect of good analgesic effect, curative effect, nontoxic, medicine source abundant, cost is low.

Embodiment 1

Step 1,

Each raw material is taken: propolis 3g, Borneolum Syntheticum 0.7g, Cortex Phellodendri 12g, Cera Flava 17g, Radix Sanguisorbae 10g, Radix Rehmanniae 5g, Rhizoma Coptidis 5g, Radix Et Rhizoma Rhei 10g, Radix Scutellariae 5g, Radix Arnebiae (Radix Lithospermi) 2g, Oleum Sesami 500g according to following mass fraction;

Step 2,

Borneolum Syntheticum, the Radix Rehmanniae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi) are ground into fine powder respectively, cross 80 mesh sieves, for subsequent use;

Step 3,

Oleum Sesami and Cera Flava are put into pot heat while stirring, after Cera Flava melts, stop heating, be cooled to 70 DEG C and add Borneolum Syntheticum, continue to be cooled to 50 DEG C and add propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Et Rhizoma Rhei, be fully uniformly mixed, make thick paste.

Embodiment 2

Step 1,

Each raw material is taken: propolis 5g, Borneolum Syntheticum 0.5g, Cortex Phellodendri 15g, Cera Flava 10g, Radix Sanguisorbae 5g, Radix Rehmanniae 10g, Rhizoma Coptidis 8g, Radix Et Rhizoma Rhei 5g, Radix Scutellariae 10g, Radix Arnebiae (Radix Lithospermi) 1g, Oleum Sesami 450g according to following mass fraction;

Step 2,

Borneolum Syntheticum, the Radix Rehmanniae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi) are ground into fine powder respectively, cross 100 mesh sieves, for subsequent use;

Step 3,

Oleum Sesami and Cera Flava are put into pot heat while stirring, after Cera Flava melts, stop heating, be cooled to 75 DEG C and add Borneolum Syntheticum, continue to be cooled to 40 DEG C and add propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Et Rhizoma Rhei, be fully uniformly mixed, make paste.

Embodiment 3

Step 1,

Each raw material is taken: propolis 3g, Borneolum Syntheticum 1g, Cortex Phellodendri 5g, Cera Flava 20g, Radix Sanguisorbae 7g, Radix Rehmanniae 9g, Rhizoma Coptidis 8g, Radix Et Rhizoma Rhei 7g, Radix Scutellariae 6g, Radix Arnebiae (Radix Lithospermi) 3g, Oleum Sesami 550g according to following mass fraction;

Step 2,

Borneolum Syntheticum, the Radix Rehmanniae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi) are ground into fine powder respectively, cross 120 mesh sieves, for subsequent use;

Step 3,

Oleum Sesami and Cera Flava are put into pot heat while stirring, after Cera Flava melts, stop heating, be cooled to 70 DEG C and add Borneolum Syntheticum, continue to be cooled to 45 DEG C and add propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Et Rhizoma Rhei, be fully uniformly mixed, make thick paste.

Embodiment 4

Step 1,

Each raw material is taken: propolis 4g, Borneolum Syntheticum 0.7g, Cortex Phellodendri 14g, Cera Flava 13g, Radix Sanguisorbae 8g, Radix Rehmanniae 6g, Rhizoma Coptidis 7g, Radix Et Rhizoma Rhei 9g, Radix Scutellariae 8g, Radix Arnebiae (Radix Lithospermi) 3g, Oleum Sesami 520g according to following mass fraction;

Step 2,

Borneolum Syntheticum, the Radix Rehmanniae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi) are ground into fine powder respectively, cross 90 mesh sieves, for subsequent use;

Step 3,

Oleum Sesami and Cera Flava are put into pot heat while stirring, after Cera Flava melts, stop heating, be cooled to 80 DEG C and add Borneolum Syntheticum, continue to be cooled to 47 DEG C and add propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Et Rhizoma Rhei, be fully uniformly mixed, make thick paste.

The invention provides a kind of method this Chinese medicine composition being prepared as thick paste or paste, but do not limit and can only adopt the preparation of this kind of method, do not form the restriction to this Chinese medicine composition, other method well known in the art also can be adopted to prepare.

Claims (1)

1. treat a preparation method for burn and scald Chinese medicine composition, it is characterized in that, comprise the following steps:

Step 1,

Each raw material is taken: propolis 3-5 part, Borneolum Syntheticum 0.5-1 part, Cortex Phellodendri 5-15 part, Cera Flava 10-20 part, Radix Sanguisorbae 5-10 part, Radix Rehmanniae 5-10 part, Rhizoma Coptidis 5-10 part, Radix Et Rhizoma Rhei 5-10 part, Radix Scutellariae 5-10 part, Radix Arnebiae (Radix Lithospermi) 1-3 part, Oleum Sesami 450-550 part according to following mass fraction;

Step 2,

Borneolum Syntheticum, the Radix Rehmanniae, Rhizoma Coptidis, Radix Arnebiae (Radix Lithospermi) are ground into fine powder respectively, cross 80-120 mesh sieve, for subsequent use;

Step 3,

Oleum Sesami and Cera Flava are put into pot heat while stirring, after Cera Flava melts, stop heating, be cooled to 70-80 DEG C and add Borneolum Syntheticum, propolis, the Radix Rehmanniae, Radix Sanguisorbae, Rhizoma Coptidis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Radix Et Rhizoma Rhei is added after continuing to be cooled to 40-50 DEG C, fully be uniformly mixed, make thick paste or paste.