CN103566052B - 一种治疗甲状腺肿瘤的中药 - Google Patents
一种治疗甲状腺肿瘤的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗甲状腺肿瘤的中药，其特征在于，它是由以下重量配比的原料药材制备而成：七星剑3份、地锦草3份、偷筋草4份、桃金娘3份、杜仲3份、当归6份、赛金刚3份、甜远志12份、散血莲3份、肾子草6份、菩提树花4份、破布草5份、沉香3份、赤芍3份、苦丁茶8份、大将军4份、佩兰6份、破布木6份、乌桕叶3份、白头翁6份、乌蛇2份。临床实验证明，本发明能够安全有效治疗甲状腺肿瘤。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗甲状腺肿瘤的中药。
背景技术
甲状腺肿瘤是头颈部常见的肿瘤，女性多见。症状为颈前正中肿块，随吞咽活动，部分病人还有声音嘶哑和吞咽困难、呼吸困难。目前治疗甲状腺肿瘤的药物效果不都理想，且有较大毒副作用。不得己采用手术切除，费用昂贵，风险较大，且愈后易复发。因此研究开发一种安全有效的治疗甲状腺肿瘤的中药非常有实用价值。
本发明中药所涉及药材的研究现状如下：
七星剑：本品为唇形科植物细叶七星剑的全草。【性味】味辛；性微温。【归经】归肝；脾经。【功能主治】发汗解暑；利湿角毒。主感冒；中者；呕吐；泄泻；水肿；湿疹；疮疡肿毒；带状疱疹；阴疽瘰疬；跌打伤痛；毒蛇咬伤。
地锦草：本品为大戟科植物地锦Euphorbia humifusa Willd.或斑地锦Euphorbia maculata L.的干燥全草。【性味】辛，平。【归经】归肝、大肠经。【功能主治】清热解毒，凉血止血。用于痢疾，泄泻，咳血，尿血，便血，崩漏，疮疖痈肿。
偷筋草：本品为报春花科植物四川报春的全草。【性味】辛；性微温。【功能主治】活血消肿。主跌打肿痛。
桃金娘：本品为桃金娘科植物桃金娘Rhodomyrtus tomentosa （Ait.）Hassk.，以根、叶和果入药。【性味】甘、涩，平。【功能主治】根：祛风活络，收敛止泻。用于急、慢性肠胃炎，胃痛，消化不良，肝炎，痢疾，风湿性关节炎，腰肌劳损，功能性子宫出血，脱肛；外用治烧烫伤。【用法用量】根、叶、果6-10g。
杜仲：本品为杜仲科植物杜仲EucommiaulmoidesOliv.的干燥树皮。【性味与归经】甘，温。归肝、肾经。【功能与主治】补肝肾，强筋骨，安胎。用于肝肾不足，腰膝酸痛，筋骨无力，头晕目眩，妊娠漏血，胎动不安。
当归：本品为伞形科植物当归Angelica sinensis （Oliv.） Diels 的干燥根。【性味】甘、辛，温。【归经】归肝、心、脾经。【功能主治】补血活血，调经止痛，润肠通便。用于血虚萎黄，眩晕心悸，甲状腺肿瘤，经闭痛经，虚寒腹痛，肠燥便秘，风湿痹痛，跌扑损伤，痈疽疮疡。酒当归活血通经。用于经闭痛经，风湿痹痛，跌扑损伤。
赛金刚：本品为葫芦科植物棒锤瓜的块根。 【性味】味苦；涩；性寒。【功能主治】清热解毒；止痛。主菌痢；肠炎；胃炎；咽喉炎；腮腺炎；牙周炎；暴发火眼；扁桃体炎；高热；***。
甜远志：本品为远志科植物宽叶远志的干燥根。【性味归经】温；苦、辛；归心、肾、肺经。【功能主治】安神益智，祛痰，消肿。用于心肾不交引起的失眠多梦、健忘惊悸，神志恍惚，咳痰不爽，疮疡肿毒，***肿痛。
头巾草：本品为唇形科植物并头黄芩的全草。【性味】味微苦；性凉。【功能主治】清热利湿；解毒消肿。主肝炎；肝硬化腹水；阑尾炎；乳腺炎；蛇虫咬伤；跌打损伤。
散血莲：本品为裸子蕨科植物凤丫蕨的根茎或全草。【性味】微辛；寒；微苦；凉。【归经】肝经。【功能主治】祛风除湿；散血止痛；清热解毒。主风湿关节痛；瘀血腹痛；闭经；跌打损伤；目赤肿痛；乳痈；各种肿毒初起。
肾子草：本品为玄参科植物***婆婆纳的全草。【性味】味辛；苦；咸；性平。【功能主治】祛风除湿；壮腰；截疟。主风湿痹痛；肾虚腰痛；外疟。
土砂仁：本品为姜科植物和山姜的果实或种子。【性味】苦辛，温。【功能主治】为芳香健胃药，能行气凋中治痞胀腹痛，呕吐腹泻。
破布草：本品为唇形科植物野甘露的全草或根。【性味】味淡；微苦；性凉。【归经】归脾；心经。【功能主治】清热解毒；拔毒止痒。主赤；白痢；疮疖；附骨疽；湿疹。
沉香：本品为瑞香科植物白木香Aquilaria sinensis （Lour.） Gilg 含有树脂的木材。【性味】辛、苦，微温。【归经】归脾、胃、肾经。【功能主治】行气止痛，温中止呕，纳气平喘。用于胸腹胀闷疼痛，胃寒呕吐呃逆，肾虚气逆喘急。
赤芍：本品为毛茛科植物芍药Paeonia lactiflora Pall.或川赤芍Paeonia veitchii Lynch 的干燥根。【性味】苦；微寒。【归经】肝；脾经。【功能主治】清热凉血；活血祛瘀。主温毒发斑；吐血衄血；肠风下血；目赤肿痛；痈肿疮疡；闭经；痛经；崩带淋浊；瘀滞胁痛；疝瘕积聚；跌扑损伤。
苦丁茶：本品为冬青科植物枸骨、大叶冬青或苦丁茶冬青的嫩叶。 【性味】甘；苦；寒。【归经】肝；肺；胃。【功能主治】疏风清热；明目生津。主风热头痛；齿痛；目赤；聤耳；口疮；热病烦渴；泄泻；痢疾。
大将军：本品为桔梗科大将军Lobelia clavata E. Wimm.，以根、叶入药。【性味】辛，凉。有毒。【功能主治】消炎，止痛，解毒，祛风，杀虫。主治风湿关节炎，跌打损伤。外用治蛇伤，痈肿。叶研末喷喉治急性扁桃腺炎。
佩兰： 本品为菊科植物佩兰Eupatorium fortunei Turcz.的干燥地上部分。【性味】辛，平。【归经】归脾、胃、肺经。【功能主治】芳香化湿，醒脾开胃，发表解暑。用于湿浊中阻，脘痞呕恶，口中甜腻，口臭，多涎，暑湿表症，头胀胸闷。
破布木：本品为紫草科破布木Cordia dichotoma Forst. f.，以根、果入药。【性味】微甘，平。【功能主治】行气止痛，化痰止咳。心胃气痛，湿热腹泻，急、慢性支气管炎。
乌桕叶：本品为大戟科植物乌桕Sapium sebiferum （L.）Roxb.的叶。【性味】苦；微温；有毒。【归经】心经。【功能主治】泻下逐水；消肿散瘀；解毒杀虫。主水肿；大、小便不利；腹水；湿疹；疥癣；痈疮肿毒；跌打损伤；毒蛇咬伤。
白头翁：本品为毛茛科植物白头翁Pulsatilla chinensis （Bge.） Regel的干燥根。【性味】苦，寒。【归经】归胃、大肠经。【功能主治】清热解毒，凉血止痢。用于热毒血痢，阴痒带下，阿米巴痢。
乌蛇：本品为游蛇科动物乌梢蛇除去内脏的全体。【性味】甘咸，平。【归经】入肺、脾经。【功能主治】祛风湿，通经络。治风湿顽痹，肌肤不仁，骨、关节结核，风疹疥癣，麻风，破伤风，小儿麻痹症。
发明内容
本发明旨在提供一种治疗甲状腺肿瘤的中药，通过选择合适的药材及其配比，达到安全有效治愈甲状腺肿瘤的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗甲状腺肿瘤的中药，其特征在于，它是由以下重量配比的原料药材制备而成：
七星剑3份、地锦草3份、偷筋草4份、桃金娘3份、杜仲3份、当归6份、赛金刚3份、甜远志12份、散血莲3份、肾子草6份、破布草5份、沉香3份、赤芍3份、苦丁茶8份、大将军4份、佩兰6份、破布木6份、乌桕叶3份、白头翁6份、乌蛇2份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年1月-2013年3月间共收集75例甲状腺肿瘤患者，年龄22-59岁，病程3个月~3年。随机分为：治疗组50例，对照组25例。两组性别、年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗方法
对照组口服甲氨蝶呤，按照其说明书服用。疗程3个月。
治疗组口服本发明按照具体实施例1制得的胶囊，每日2次。疗程3个月。
2.2观察项目：实验前后，对疼痛情况，肿块大小，萎缩情况等情况进行观察，记录。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常，愈后半年内未见复发。好转：临床症状减轻，实验室检查改善或正常。无效：临床症状、实验室检查无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 严重不良反应例 | 总有效率(%) |
| 治疗组 | 50 | 33 | 10 | 10 | 0 | 86% |
| 对照组 | 25 | 5 | 10 | 10 | 11（44%） | 60% |
可见，本发明制得的药物能够安全有效治疗甲状腺肿瘤。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取七星剑3g、地锦草3g、偷筋草4g、桃金娘3g、杜仲3g、当归6g、赛金刚3g、甜远志12g、散血莲3g、肾子草6g、菩提树花4g、破布草5g、沉香3g、赤芍3g、苦丁茶8g、大将军4g、佩兰6g、破布木6g、乌桕叶3g、白头翁6g、乌蛇2g;加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人一天用量的胶囊剂。
用于治疗甲状腺肿瘤。口服，每日分早晚两次服用。
具体实施例2
称取七星剑3g、地锦草3g、偷筋草4g、桃金娘3g、杜仲3g、当归6g、赛金刚3g、甜远志12g、散血莲3g、肾子草6g、菩提树花4g、破布草5g、沉香3g、赤芍3g、苦丁茶8g、大将军4g、佩兰6g、破布木6g、乌桕叶3g、白头翁6g、乌蛇2g；加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常成人一天用量的散剂。
用于治疗甲状腺肿瘤。口服，每日一次。
具体实施例3
称取七星剑3g、地锦草3g、偷筋草4g、桃金娘3g、杜仲3g、当归6g、赛金刚3g、甜远志12g、散血莲3g、肾子草6g、菩提树花4g、破布草5g、沉香3g、赤芍3g、苦丁茶8g、大将军4g、佩兰6g、破布木6g、乌桕叶3g、白头翁6g、乌蛇2g；加6倍量水，煎煮3次，每次煎煮1小时，合并煎煮液，浓缩，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人一天用量的颗粒剂。
用于治疗甲状腺肿瘤。口服，每日分早中晚三次服用。
Claims (1)
1.一种治疗甲状腺肿瘤的中药，其特征在于，它是由以下重量配比的原料药材制备而成：七星剑3份、地锦草3份、偷筋草4份、桃金娘3份、杜仲3份、当归6份、赛金刚3份、甜远志12份、散血莲3份、肾子草6份、菩提树花4份、破布草5份、沉香3份、赤芍3份、苦丁茶8份、大将军4份、佩兰6份、破布木6份、乌桕叶3份、白头翁6份、乌蛇2份。
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| CN103156986A (zh) * | 2013-03-19 | 2013-06-19 | 张冠珍 | 一种治疗神经纤维瘤的中药制剂 |
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| CN1485083A (zh) * | 2003-06-13 | 2004-03-31 | 许新琳 | 甲状腺癌瘤***胶囊 |
| CN103156986A (zh) * | 2013-03-19 | 2013-06-19 | 张冠珍 | 一种治疗神经纤维瘤的中药制剂 |
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