CN103550520B - Traditional Chinese medicinal preparation for treating gastric ulcer and preparation method thereof - Google Patents

Traditional Chinese medicinal preparation for treating gastric ulcer and preparation method thereof Download PDF

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CN103550520B
CN103550520B CN201310542606.3A CN201310542606A CN103550520B CN 103550520 B CN103550520 B CN 103550520B CN 201310542606 A CN201310542606 A CN 201310542606A CN 103550520 B CN103550520 B CN 103550520B
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杨国荣
张泽金
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Abstract

The invention relates to a traditional Chinese medicinal preparation for treating gastric ulcer and a preparation method thereof. Raw materials of effective components of the traditional Chinese medicinal preparation are rhizoma bletillae, rhizoma nardostachyos, saffron, plant soot, ovateleaf holly bark, mango stone, Indian kalimeris herb, sword bean, zanthoxylum planispinum, joint vetch, herba desmodii caudati, bauhinia root, cylea sutchuenensis gagnep, turnip, securidaca inappendiculata and tofieldia yunnanensis franch. The traditional Chinese medicinal preparation selects compatible drug materials, accords with traditional Chinese medical and modern medical research theories, is prepared by adopting a modern advanced medical pharmacy technology, has the effects of clearing heat and resolving depression, absorbing stasis and activating blood circulation, and regulating qi-flowing for harmonizing stomach, has a remarkable curative effect on epigastric pain, gastric ulcer and duodenal ulcer, can be used for improving gastric motility and restoring normal metabolism of stomach, is long in acting time, short in course of treatment, quick in response and safe, does not have toxic or side effect, and can be widely applied to clinical treatment of gastric ulcer.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of gastric ulcer
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicine preparation and preparation method for the treatment of gastric ulcer.
Background technology
Gastric ulcer is a kind of quite common digestive system disease, and its Etiological is owing to having infected helicobacter pylori, and abuses, abuses NSAID (non-steroidal anti-inflammatory drug) etc.Gastric ulcer is a chronic process, it plays gesture suddenly unlike dysentery, this disease of cholera, many patients often in several years even in the middle of decades all without any obvious symptom of digestive tract, or symptom is very slight, to such an extent as to is not found by patient completely.
Epigastrium pain is the cardinal symptom of gastric ulcer, and pain multidigit, in epigastrium, also can appear at after left upper abdomen, breastbone or xiphoid-process, is often dull pain, dull pain, distending pain, burns the pain such as sample pain.The pain of gastric ulcer is many to be occurred in 1 hour after the meal, after 1~2 hour, alleviated gradually, until reappear the above-mentioned rhythm and pace of moving things after the feed of lower meal, some patients were can be asymptomatic again, or using complication such as hemorrhage, perforation as onset symptoms.
If gastric ulcer can not be treated in time, can cause a series of complication, as upper gastrointestinal hemorrhage, perforated ulcer, pyloric obstruction etc., severe patient even causes canceration, serious threat patient's life security.
For the treatment of gastric ulcer; the medicine that more options damage factor is lower at present, as synthetics and the omeprazole etc. of antacid, anticholinergic agent, H2 receptor antagonist, proglumide, PGE2, gives the medicine of gastric mucosal protection as sucralfate, bismuth, carbenoxolone (carbenoxolone) etc. and antibiotic application simultaneously.Because said medicine mostly is chemicals, in treatment gastric ulcer, patient's stomach is also caused to certain side effect, patient is caused to huge injury, and curative effect of medication is limited, often delay the state of an illness, make state of an illness migration, make conditions of patients more serious.
For this reason, through the research to Chinese materia medica and modern medicine, we have developed a kind of Chinese medicine preparation of safe and effective short treating period instant effect and have treated gastric ulcer, make patients w ith peptic ulcer disease obtain better therapeutic effect.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of gastric ulcer, the selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and modern medicine research theory, and adopt modern advanced medical pharmaceutical technology to make, there is effect of heat clearing away resolving depression, eliminating blood stasis and promoting blood circulation, regulating qi-flowing for harmonizing stomach, all there is significant curative effect for gastric abscess, gastric ulcer and duodenal ulcer, and can improve gastric motility, recover stomach eubolism, long action time, short treating period instant effect, safe without toxic side effect, can be widely used in the clinical treatment of gastric ulcer.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for gastric ulcer, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of gastric ulcer, comprise following processing step:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Nardostachyos, Stigma Croci, Pulvis Fumi Carbonisatus, Cortex Ilicis Rotundae, Herba desmodii multifloi and Radix Cycleae Racemosae decontamination, clean and put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, reserved filtrate, by the thick paste of relative density 1.20~1.25 under 60 DEG C of environment of filtrate simmer down to, for subsequent use;
(2) get Semen Mangiferae indicae and Semen Canavaliae decontamination, under daylight, be exposed to the sun, after drying, be placed in mortar and grind into powder, cross 200 order fine powders, for subsequent use;
(3) get Herba Kalimeridis, Herba Aeschynonenes Indicae and Radix Brassicae rapae decontamination and clean, put into agitator and rub, taking juice is for subsequent use;
(4) get Fructus Zanthoxyli Plansipini, Radix Bauhihiae Championii, Radix securidacae and demutation grass decontamination and clean, dry, add 80% alcoholic solution of 5 times of amounts, soak 2-4 hour, heating extraction 2-3 hour, reclaims ethanol, filters, and reserved filtrate is for subsequent use;
(5) above-mentioned steps (1)-(4) prepared thick paste, fine powder, juice and filtrate are mixed, utilize modern advanced pharmacy science and technology, make tablet, be the Chinese medicine preparation of described treatment gastric ulcer.
The property of medicine of the present invention's Chinese medicine used is as follows:
Pseudobulbus Bletillae (Rhizoma Bletillae): bitter in the mouth, sweet, cool in nature; Enter lung meridian.Tonifying the lung, hemostasia and detumescence, promoting tissue regeneration and ulcer healing.Cure mainly lung and hinder hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, ulcer pain, soup fire is burnt, rhagadia manus et pedis." herbal classic " carries: " main carbuncle malignant boil loses cellulitis, the dead flesh of impairment of YIN, and pathogen in stomach, harmful wind miliaria is slow not to be received.”
Radix Et Rhizoma Nardostachyos: sweet in the mouth, warm in nature; Enter spleen, stomach warp.Regulating QI to relieve pain, activating spleen and strengthening stomach.Cure mainly stomachache, distension and fullness of the chest and abdomen, headache, hysteria, beriberi." modern Practical Chinese medicinal " carries: " be applicable to headache, stomachache and the card such as depressed, and can drive ascarid, all because of the ascarid person that sends out infantile convulsion, effective with this.”
Stigma Croci: sweet in the mouth, property is flat; GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, resolving stagnation for tranquilization.For amenorrhea lump in the abdomen, postpartum stagnation, maculae caused by violent heat pathogen, melancholy painful abdominal mass is vexed, and palpitation with fear is gone mad.
Pulvis Fumi Carbonisatus: bitter in the mouth, pungent, warm in nature; Return liver, lung, stomach warp.Hemostasis removing food stagnancy, sterilizing powdered medicine fire.Cure mainly haematemesis, epistaxis, has blood in stool, metrorrhagia, leukorrhagia, food stagnation, dysentery, jaundice, laryngopharynx swelling and pain, aphtha of the mouth and tongue, ecthyma, white bareheaded skin ulcer, traumatic hemorrhage." medical center bun will " carries: " removing pathogen in the heart pathogenic fire reducing, goes absurd heat, stops absurd blood, the capable expectorant of therapeutic method to keep the adverse QI flowing downwards removing food stagnancy.”
Cortex Ilicis Rotundae: bitter in the mouth, cold in nature; Return lung, liver, large intestine channel.Heat-clearing and toxic substances removing, dampness removing pain relieving.Cure mainly cold, fever, laryngopharynx swelling and pain, stomachache, administration's diarrhea due to damp pathogen rushes down, jaundice, dysentery, traumatic injury, rheumatic arthralgia, eczema, furuncle.
Semen Mangiferae indicae: sour in the mouth, puckery, property is flat; Return stomach, small intestine meridian.Invigorating the stomach and promoting digestion, the circulation of qi promoting of reducing phlegm.Cure mainly eating accumulation, inappetence, cough, hernia, orchitis.
Herba Kalimeridis: acrid in the mouth, hardship, cold in nature; Return lung, liver, stomach, large intestine channel.Heat-clearing and toxic substances removing, dissipating blood stasis hemostasis, removing food stagnancy.For cat fever, cough, acute pharyngitis, tonsillitis, mumps, infectious hepatitis, Stomach duodenum ulcer, infantile malnutrition, enteritis, dysentery, spits blood, metrorrhagia, menoxenia; Skin ulcer is controlled in external, furuncle and phyma pain, mastitis, traumatic hemorrhage." detailed outline " carries: " root, leaf, main all malarias and spasm and pain in the abdomen, hemorrhoid.”
Semen Canavaliae: sweet in the mouth, warm in nature; Return stomach, kidney channel.Warming the middle warmer and descending qi, kidney tonifying complement.Cure mainly deficiency and coldness singultus, vomiting, abdominal distention, lumbago due to renal deficiency, phlegm dyspnea." Chinese crude drug handbook " carries: " the kidney invigorating, cold expelling, the therapeutic method to keep the adverse QI flowing downwards, sharp the intestines and stomach, preventing or arresting vomiting is told.Control kidney qi deficient, the intestines and stomach discord, vomiting, abdominal distention, vomits and diarrhoea.”
Fructus Zanthoxyli Plansipini: acrid in the mouth, micro-hardship, warm in nature, mild toxicity; Return lung, large intestine channel.The dry temperature of warming middle-JIAO, dispersing cold for relieving pain, expelling insect and relieving itching.Cure mainly coldness and pain in the epigastrium, cold-damp is vomited and diarrhoea, ascariasis of biliary tract stomachache, toothache due to dental caries, eczema, scabies itching sore." Guangxi medicine is planted register " carries: " promoting the circulation of QI for relieving swelling, the dissipating blood stasis that dispels the wind, cough-relieving, the ascarid of dispelling.Treat for stomachache.”
Herba Aeschynonenes Indicae: slightly sweet flavor, cold in nature; Return through lung, stomach warp.Wind is removed in heat clearing away, inducing diuresis and reducing edema, removing toxic substances.Cure mainly anemopyretic cold, jaundice, dysentery, gastritis, abdominal distention, gonorrhea, carbuncle, dermatitis, eczema.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " heat clearing away disappears stagnant.Control flatulence, dyspepsia, ache induced by gastritis, anemopyretic cold, eczema, dermatitis.”
Herba desmodii multifloi: sweet in the mouth, hardship, cool in nature; Return lung, stomach, liver, gallbladder meridian.Promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling.Cure mainly epigastric pain, infantile malnutrition, women's emaciation due to blood disorder, lumbar sprain, wound, urethritis, parotitis, venom." Guangxi Chinese herbal medicine " carries: " pain relieving that helps digestion, antidotes against snake bite.Control gastropathy, infantile malnutrition, venom.”
Radix Bauhihiae Championii: sweet in the mouth, hardship, warm in nature; Return spleen, Liver Channel.Wind-damp dispelling, promoting the circulation of blood gas.Cure mainly traumatic injury, rheumatic ostalgia, heart peratodynia." Luchuan book on Chinese herbal medicine " carries: " promoting the circulation of QI to relieve pain, control heart peratodynia, rheumatic ostalgia, lumbago.”
Radix Cycleae Racemosae: bitter in the mouth, cold in nature.Qingre Liqi, eliminating stasis to stop pain.For acute gastroenteritis, dyspepsia, heatstroke stomachache, stomachache, affection due to external wind and heat, cough, laryngopharynx swelling and pain, damp-heat dysentery, toothache, traumatic pain, urine leaching is puckery.
Radix Brassicae rapae: bitter in the mouth, pungent, sweet, warm in nature; GUIXIN, lung, spleen, stomach warp.Removing stagnancy of indigested food and making QI downward, removing toxic substances and promoting subsidence of swelling.Cure mainly indigestion, trusted subordinate's cold type of pain, cough, furuncle carbuncle." Treatise on Dietetic Therapy " carries: " therapeutic method to keep the adverse QI flowing downwards, the subcutaneous ulcer of harnessing the Yellow River, diuresis.Root, main quenching one's thirst, controls pyretic toxicity swelling due to wind.Boil as thick soup and eat it the eleventh month of the lunar calendar as ancient sacrificial utensil, the dyspepsia that can disappear, and the therapeutic method to keep the adverse QI flowing downwards, controls and coughs.”
Radix securidacae: acrid in the mouth, hardship, cold nature.Promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain, clearing away heat and promoting diuresis.Cure mainly acute gastroenteritis, traumatic injury, rheumatic ostalgia.
Demutation grass: lightly seasoned, property is flat.Inducing diuresis and regulating menstruation, YIN nourishing tonify deficiency.Cure mainly edema, dizziness, tinnitus, infantile malnutrition, menoxenia, stomachache, infantile diarrhea.
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and modern medicine research theory, and adopt modern advanced medical pharmaceutical technology to make, there is effect of heat clearing away resolving depression, eliminating blood stasis and promoting blood circulation, regulating qi-flowing for harmonizing stomach, all there is significant curative effect for gastric abscess, gastric ulcer and duodenal ulcer, and can improve gastric motility, recover stomach eubolism, long action time, short treating period instant effect, safe without toxic side effect, can be widely used in the clinical treatment of gastric ulcer.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Nardostachyos, Stigma Croci, Pulvis Fumi Carbonisatus, Cortex Ilicis Rotundae, Herba desmodii multifloi and Radix Cycleae Racemosae decontamination, clean and put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, reserved filtrate, by the thick paste of relative density 1.20~1.25 under 60 DEG C of environment of filtrate simmer down to, for subsequent use;
(2) get Semen Mangiferae indicae and Semen Canavaliae decontamination, under daylight, be exposed to the sun, after drying, be placed in mortar and grind into powder, cross 200 order fine powders, for subsequent use;
(3) get Herba Kalimeridis, Herba Aeschynonenes Indicae and Radix Brassicae rapae decontamination and clean, put into agitator and rub, taking juice is for subsequent use;
(4) get Fructus Zanthoxyli Plansipini, Radix Bauhihiae Championii, Radix securidacae and demutation grass decontamination and clean, dry, add 80% alcoholic solution of 5 times of amounts, soak 2-4 hour, heating extraction 2-3 hour, reclaims ethanol, filters, and reserved filtrate is for subsequent use;
(5) above-mentioned steps (1)-(4) prepared thick paste, fine powder, juice and filtrate are mixed, utilize modern advanced pharmacy science and technology, make tablet, be the Chinese medicine preparation of described treatment gastric ulcer.
Usage and dosage: oral, each 2 every day 3 times, 7 days is a course for the treatment of, and can fully recover 3 to 5 courses for the treatment of; The person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
The present embodiment Chinese drugs agentia preparation method processing step and usage and dosage are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of gastric ulcer, select patients w ith peptic ulcer disease 150 examples to carry out clinical observation, patient is divided into two groups at random, treatment group 75 examples, wherein male 36 examples, women's 39 examples, age 20-60 year, 38.9 years old mean age, course of disease 1-10; Matched group 75 examples, wherein male 37 examples, women's 38 examples, age 20-60 year, 38.6 years old mean age, course of disease 1-10; Two groups of patient medical record are basically identical, without significant difference, have comparability, all keep on a diet on request for two groups.
2, treatment group person's trouble is taken Chinese medicine preparation of the present invention, and oral, each 2 every day 3 times, 7 days is a course for the treatment of, takes continuously 3 to 5 courses for the treatment of and can fully recover, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding; Matched group is taken KUIYANGLING JIAONANG, by specification use, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
3, curative effect judgement:
Cure: stomach dull pain, dull pain, distending pain, burn the stomach pain such as sample pain and disappear, gastric motility recovers, and metabolism recovers normally.
Take a turn for the better: stomach discomfort alleviates, and gastric motility recovers to some extent.
Invalid: symptom is unchanged.
4, therapeutic outcome:
Treatment group: cure 51 examples, 21 examples that take a turn for the better, invalid 3 examples, cure rate is 68%, total effective rate is 96%.
Matched group: cure 36 examples, 18 examples that take a turn for the better, invalid 21 examples, cure rate is 48%, total effective rate is 72%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
5, model case is for example:
(1) field, female, 56 years old, peasant, Hengyang, Hunan Province people.Distending pain under xiphoid-process before patient half a year; there is after meal feeling of repletion, occasionally have Yuan gas, return acid, dull pain under xiphoid-process; be paroxysmal; be admitted to hospital and do gastroscopy, be diagnosed as gastric ulcer, give after antacid, protection gastric mucosa conventional treatment at hospital's Digestive System Department; remission; after again there is above-mentioned symptom, again in Digestive System Department diagnosis and treatment, but symptom fail alleviate.Recommend to take 4 courses for the treatment of of Chinese medicine preparation of the present invention by doctor, recovery from illness, follows up a case by regular visits to and has no recurrence.
(2) together certain, female, 46 years old, teacher, Yuncheng, Shanxi people.Patient suffers from gastric ulcer, and with gastrorrhagia history, is admitted to hospital and does the stool inspection occult blood positive, and rear burst is spitted blood, listless; Recommend to start to take Chinese medicine preparation of the present invention through doctor, take 5 courses for the treatment of, recovery from illness, follows up a case by regular visits to and has no recurrence.
(3) Lin, man, 32 years old, workman, Yancheng, Jiangsu Province people.Under patient's xiphoid-process and rear backache, appetite is poor, without becoming thin, xiphoid-process presses down pain, and by treating gastritis half a year, symptom is without alleviation, also do gastroscopy demonstration without obviously worsening, being admitted to hospital, see that from the nearly cardia of body of stomach two dark large ulcer sexually transmitted disease (STD)s become, the thick greasy white fur of surface attachment and a little blood cangue and the dirt of ulcer, ulcer bottom is slightly aobvious uneven, does not find cancerous cell, mucosal tissue, body of gland rareness, little blood vessel hyperplasia, interstitial is shown in lymphocyte infiltration and neutrophil cell, plasma cell, acidophil.Rear patient started to take after 5 courses for the treatment of of Chinese medicine preparation of the present invention, again checked, showed state of an illness recovery from illness, followed up a case by regular visits to and had no recurrence.

Claims (5)

1. a Chinese medicine preparation for the treatment of gastric ulcer, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Pseudobulbus Bletillae (Rhizoma Bletillae) 28-50 part Radix Et Rhizoma Nardostachyos 28-50 part Stigma Croci 28-50 part Pulvis Fumi Carbonisatus 25-48 part
Cortex Ilicis Rotundae 25-48 part Semen Mangiferae indicae 25-48 part Herba Kalimeridis 22-46 part Semen Canavaliae 22-46 part
Fructus Zanthoxyli Plansipini 20-45 part Herba Aeschynonenes Indicae 20-45 part Herba desmodii multifloi 20-45 part Radix Bauhihiae Championii 18-40 part
Radix Cycleae Racemosae 18-40 part Radix Brassicae rapae 15-36 part Radix securidacae 15-36 part demutation grass 12-30 part.
2. a kind of Chinese medicine preparation for the treatment of gastric ulcer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
40 parts of 43 parts of Pulvis Fumi Carbonisatuss of 43 parts of Stigma Crocis of 43 parts of Radix Et Rhizoma Nardostachyos of Pseudobulbus Bletillae (Rhizoma Bletillae)
38 parts of 38 portions of Semen Canavaliaes of 40 parts of Herba Kalimeridis of 40 parts of Semen Mangiferae indicaes of Cortex Ilicis Rotundae
33 parts of 35 parts of Radix Bauhihiae Championiis of 35 parts of Herba desmodii multiflois of 35 parts of Herba Aeschynonenes Indicae of Fructus Zanthoxyli Plansipini
24 parts of 29 parts of demutation grass of 29 parts of Radix securidacae of 33 portions of Radix Brassicae rapaes of Radix Cycleae Racemosae.
3. a kind of Chinese medicine preparation for the treatment of gastric ulcer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
35 parts of 38 parts of Pulvis Fumi Carbonisatuss of 38 parts of Stigma Crocis of 38 parts of Radix Et Rhizoma Nardostachyos of Pseudobulbus Bletillae (Rhizoma Bletillae)
33 parts of 33 portions of Semen Canavaliaes of 35 parts of Herba Kalimeridis of 35 parts of Semen Mangiferae indicaes of Cortex Ilicis Rotundae
28 parts of 30 parts of Radix Bauhihiae Championiis of 30 parts of Herba desmodii multiflois of 30 parts of Herba Aeschynonenes Indicae of Fructus Zanthoxyli Plansipini
20 parts of 24 parts of demutation grass of 24 parts of Radix securidacae of 28 portions of Radix Brassicae rapaes of Radix Cycleae Racemosae.
4. a kind of Chinese medicine preparation for the treatment of gastric ulcer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
30 parts of 33 parts of Pulvis Fumi Carbonisatuss of 33 parts of Stigma Crocis of 33 parts of Radix Et Rhizoma Nardostachyos of Pseudobulbus Bletillae (Rhizoma Bletillae)
27 parts of 27 portions of Semen Canavaliaes of 30 parts of Herba Kalimeridis of 30 parts of Semen Mangiferae indicaes of Cortex Ilicis Rotundae
23 parts of 25 parts of Radix Bauhihiae Championiis of 25 parts of Herba desmodii multiflois of 25 parts of Herba Aeschynonenes Indicae of Fructus Zanthoxyli Plansipini
16 parts of 19 parts of demutation grass of 19 parts of Radix securidacae of 23 portions of Radix Brassicae rapaes of Radix Cycleae Racemosae.
5. a preparation method for the treatment of the Chinese medicine preparation of gastric ulcer as described in claim 1-4 any one, is characterized in that: comprise following processing step:
(1) get Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Nardostachyos, Stigma Croci, Pulvis Fumi Carbonisatus, Cortex Ilicis Rotundae, Herba desmodii multifloi and Radix Cycleae Racemosae decontamination, clean and put into container, the distilled water that adds 8-12 doubly to measure, soaked after 4-5 hour, boiled 3-4 hour, extracted; Again add 6-8 doubly to measure distilled water, boil 2-3 hour, extract; Finally add 4-6 doubly to measure distilled water, heated and boiled 1-2 hour, extracts; Merge three times extracting solution, filter, reserved filtrate, by the thick paste of relative density 1.20~1.25 under 60 DEG C of environment of filtrate simmer down to, for subsequent use;
(2) get Semen Mangiferae indicae and Semen Canavaliae decontamination, under daylight, be exposed to the sun, after drying, be placed in mortar and grind into powder, cross 200 order fine powders, for subsequent use;
(3) get Herba Kalimeridis, Herba Aeschynonenes Indicae and Radix Brassicae rapae decontamination and clean, put into agitator and rub, taking juice is for subsequent use;
(4) get Fructus Zanthoxyli Plansipini, Radix Bauhihiae Championii, Radix securidacae and demutation grass decontamination and clean, dry, add 80% alcoholic solution of 5 times of amounts, soak 2-4 hour, heating extraction 2-3 hour, reclaims ethanol, filters, and reserved filtrate is for subsequent use;
(5) above-mentioned steps (1)-(4) prepared thick paste, fine powder, juice and filtrate are mixed, utilize modern advanced pharmacy science and technology, make tablet, be the Chinese medicine preparation of described treatment gastric ulcer.
CN201310542606.3A 2013-11-05 2013-11-05 Traditional Chinese medicinal preparation for treating gastric ulcer and preparation method thereof Expired - Fee Related CN103550520B (en)

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近年来中医药治消化性溃疡概况;周志刚等;《江西中医药》;20010228;第32卷(第01期);第55页 *

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