CN103550380B - Traditional Chinese medicine composition for treating hyperostosis - Google Patents
Traditional Chinese medicine composition for treating hyperostosis Download PDFInfo
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- CN103550380B CN103550380B CN201310566035.7A CN201310566035A CN103550380B CN 103550380 B CN103550380 B CN 103550380B CN 201310566035 A CN201310566035 A CN 201310566035A CN 103550380 B CN103550380 B CN 103550380B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating hyperostosis. The composition consists of musk, gecko, lycopodium clavatum, caulis spatholobi, beautiful sweetgum fruit, ground beeltle, white paeony root, frankincense, prepared rhizome of rehmannia, the root of bidentate achyranthes, astragalus membranaceus, herba epimedii, angelica sinensis, bark of himalayan coralbean, paniculate swallowwort root, zaocys dhumnade, caulis sinomenii, radix aconiti preparata, prepared kusnezoff monkshood root, aconitine, cortex periplocae, chinese starjasmine stem and mistletoe. By adding general excipients according to a conventional process, the traditional Chinese medicine composition disclosed by the invention is prepared into clinically acceptable tablets, capsules, granules, pills, oral liquid, emplastrum, spray, ointments, liniments or tinctures. The traditional Chinese medicine composition disclosed by the invention has the effects of promoting blood circulation to remove blood stasis, relaxing tendons, activating collaterals, diminishing inflammation, relieving pain and the like, has remarkable effects for treating cervical bone hyperplasia, lumbar bone hyperplasia, knee bone hyperplasia and the like, and causes no toxic and side effects as well.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of hyperosteogeny.
Background technology
Bone matrix hyperplasia is also known as hyperplastic osteoarthritis, osteoarthritis (OA), degenerative joint disease, senile arthritis, hypertrophiarthritis, the soft tissue degeneration such as cartilage, intervertebral disc, ligament owing to forming joint, degeneration, joint margins formation bony spur, synovial membrane plumpness waits change, and there is osteoclasia, cause Secondary cases hyperosteogeny, cause joint deformity, when being subject to abnormal load, cause arthralgia, a kind of disease of the symptoms such as limitation of activity.Divide constitutional and Secondary cases two kinds.Multiple middle age or the old people being born in more than 45 years old of this disease, male is more than women, and the heavy worker of conventional waist activity and athlete easily suffer from this disease, are most commonly in the joints such as knee joint, hip, lumbar vertebra, cervical vertebra, elbow.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine composition for the treatment of hyperosteogeny.
The present invention is achieved through the following technical solutions:
The crude drug of Chinese medicine composition of the present invention consists of:
The raw material composition of Chinese medicine composition of the present invention is preferably:
The raw material composition of Chinese medicine composition of the present invention is preferably:
The raw material composition of Chinese medicine composition of the present invention is preferably:
Chinese medicine composition of the present invention conveniently technique adds customary adjuvant and makes the tablet of clinical acceptance, capsule, granule, pill, oral liquid, emplastrum, spray, ointment, liniment or tincture.
Chinese medicine composition of the present invention has blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, the effects such as anti-inflammatory analgetic, to treatment hyperosteogeny of cervical vertebra, and lumbar vertebra hyperosteogeny, the Be very effective such as knee joint hyperosteogeny, and have no side effect.
Experimental example is used for further illustrating the present invention below, but is not limited to the present invention.
One, experimental example
1, clinical observation
Capsule of the present invention (according to the preparation of embodiment 1 method) treatment hyperosteogeny 100 example, wherein male 50 example, women 50 example.
2, medicament selection
Capsule of the present invention (according to the preparation of embodiment 1 method), 0.8g/ grain, every day three times, each 2.
3, diagnostic criteria
1. this patient mostly is the middle-aged and elderly people of more than 40 years old, and with the stiff pain of waist or occur the symptoms such as numbness of lower limbs, visible part patient lumbar physiological-curvature of having a medical check-up is abnormal; Lumbar vertebra both sides muscle has tenderness.
2. the change (normotopia, position, side, left and right loxosis) of lumbar X line sheet, as patient can have lumbar curvature abnormal, lumbar lateral curvature, lumbar vertebra gap turn narrow, lumbar vertebra and facet joint hypertrophy, lumbar spondylolisthesis, the changes such as intervertebral foramina stenosis.
3. the various symptoms that lumbar hyperosteogency produces should be differentiated with multiple lumbar disc disease, and as prolapse of lumbar intervertebral disc, vertebral body sends out the region between the heart and the diaphragm deformity, vertebral tumor, the diseases such as tuberculosis of spine.
4, criterion of therapeutical effect:
" in cure the desease Standardization of diagnosis and curative effect " of implementing with reference to State Administration of Traditional Chinese Medicine 1994 drafts as follows:
Clinical recovery: tcm clinical practice symptom, sign disappear or substantially disappear;
Effective: tcm clinical practice symptom, sign obviously change;
Effective: tcm clinical practice symptom, sign all take a favorable turn;
Invalid: tcm clinical practice symptom, sign are all not improved;
5, therapeutic outcome
The Comparison of therapeutic of hyperosteogeny treated by table 1
| Group | Treatment number | Recovery from illness | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 100 | 65 | 20 | 13 | 2 | 98％ |
6, conclusion
Treatment group of the present invention takes capsule of the present invention treatment hyperosteogeny (according to the preparation of embodiment 1 method) three courses for the treatment of (9 days each courses for the treatment of) respectively, and total effective rate is 98%.
7, discuss
Moschus in pharmaceutical composition crude drug of the present invention: pungent, temperature, GUIXIN, spleen channel.To have one's ideas straightened out refreshment, promoting blood circulation to restore menstrual flow, pain relieving.Gekko Swinhonis: salty, cold.Slightly poisonous.Dispel the wind, active, eliminating stagnation.Osteomyelitis, tuberculous lymphadenitis, tumor.Arresting convulsion, removing toxic substances.Control paralysis due to windstroke, severe and migratory arthralgia pain, wind-phlegm infantile convulsion, scrofula, malignant boil.Herba Lycopodii: meridian distribution of property and flavor toil temperature, enters Liver Channel.Expelling wind and cold. dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle.External is controlled osteopatia sprain and is swollen and ache.Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Function cures mainly: enrich blood, and invigorates blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Supplementary Amplifications of the Compendium of Materia Medica: invigorate blood circulation, warm waist knee joint, paralysis.Fructus Liquidambaris is originally the dry mature fruit of Hamamelidaceae Plants Chinese sweet gum.Hardship, flat.Return liver, kidney channel.Function: dispelling, collateral-activating, diuretic stimulates the menstrual flow.Cure mainly: arthralgia, numbness contracture.Eupolyphaga Seu Steleophaga is the female worm dry body of Corydiidae insecticide eupolyphoge sinensis (Eupolyphaga sinensisWalker) or Ji eupolyphoge sinensis (Steleophaga plancyi, i.e. Boleny).Salty, cold; Slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.The Radix Paeoniae Alba: picric acid is cool.Enter liver, spleen channel.Nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant.Olibanum: arduous, temperature.Enter the heart, liver, spleen channel.Function cures mainly: regulating qi and activating blood, and analgesic therapy chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury." pearl sac ": fixed all warps pain.Radix Rehmanniae Preparata: sweet in the mouth; Warm in nature.Liver Channel; Kidney channel.Enrich blood moist; Benefit essence fills out marrow.Radix Achyranthis Bidentatae: nature and flavor are bitter; Acid; Property is put down.Dispel-wind drug; Blood circulation and stasis-eliminating medicine." herbal classic ": main cold-damp flaccidity syndrome and arthralgia syndrome, spasm of the limbs, gonalgia can not be bent, by vim and vigour.The Radix Astragali: nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, kidney channel.There is effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Herba Epimedii: acrid, sweet, warm.Return liver, kidney channel.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture.Radix Angelicae Sinensis: sweet in the mouth; Pungent; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Hematonic; Emmenagogue; Analgesic.Cortex erythrinae is the dried bark of leguminous plant erythrina indica.Toil, flat.Enter liver, spleen channel.Wind-damp dispelling, the meridian dredging, parasite killing.Dispelling the wind and dampness pathogens arthralgia pain, dysentery, toothache, scabies." south of the Five Ridges gather medicinal herbs record ": granulation promoting, pain relieving, loose blood, steamed cold noodles skin, applies traumatic injury.Radix Cynanchi Paniculati: nature and flavor: pungent, temperature.Gui Jing: return Liver Channel, stomach warp.Function: removing dampness of dispeling the wind, antalgesic-antipruritic.Cure mainly: for rheumatic arthralgia, stomachache distension, toothache, lumbago, injury from falling down.Zaocys: sweet is flat.Return Liver Channel.Dispel the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm.Caulis Sinomenii: the property of medicine: flat.Flavour of a drug: bitter, pungent.Gui Jing: return liver, spleen channel.Function: wind-damp dispelling, the meridian dredging.Cure mainly: for rheumatic arthralgia, arthroncus, paralysis pruritus.Radix Aconiti Preparata: pungent, bitter, heat; Poisonous.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, mastalgia, chest pain with distension sensation, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.Radix Aconiti Kusnezoffii Preparata: nature and flavor: pungent, bitter, heat; Poisonous.Gui Jing: GUIXIN, liver,kidney,spleen warp.Effect: expelling wind and removing dampness, antalgic.Cure mainly: for anemofrigid-damp arthralgia, arthralgia.Radix aconiti kongboensis: warm in nature, bitter in the mouth fiber crops, very toxic.Anti-inflammatory analgetic, expelling wind and removing dampness.Cortex Periplocae is the dry root bark of Asclepiadaceae plant P. sepium Bunge Periploca sepium Bge..Cortex Periplocae: pungent, bitter, temperature; Poisonous.Wind-damp dispelling, bone and muscle strengthening.For anemofrigid-damp arthralgia, soreness of the waist and knees, shortness of breath and palpitation, edema of lower limbs.Caulis Trachelospermi: bitter, is slightly cold.GUIXIN, liver, kidney channel.There is expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, clearing away heat and cooling blood, effect of removing toxic substances and promoting subsidence of swelling.Herba Visci: bitter in the mouth, sweet, property is put down.Return liver, kidney channel.Relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation to remove blood stasis.For bones and muscles pain, limbs contracture, aching pain in waist and back.The all medicine merging of the present invention have blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, the effects such as anti-inflammatory analgetic, to treatment hyperosteogeny of cervical vertebra, and lumbar vertebra hyperosteogeny, the Be very effective such as knee joint hyperosteogeny, and have no side effect.
Experimental example two, model case
Case 1: Wu, female, 55 years old.Symptom: start at the beginning of patient 2011 to feel that left leg is swollen, the tired pain in left hip joint place, whole left lower extremity is numb, and do not check, carry out closed treating with " prednisone ", symptom alleviates.There is again above symptom in February, 2013.CT examination: lumbar vertebra L2-5 in hypertrophy in various degree, L3/4, L4/5 intervertebral disk hernia, compressing dural sac.May 13 examined, little leg outer side pain numbness, caused the hip arthralgia time heavy, movable and overcast and rainyly increased the weight of.Deep,thready and forceless pulse, red tongue, aversion to cold and cold limbs.Diagnosis: lumbar vertebra hyperosteogeny; Treatment: blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic; Two courses for the treatment of are treated, every day three times, each 2 by taking capsule of the present invention (according to the preparation of embodiment 1 method).Arthralgia is clearly better, and knee joint function obviously improves, and patient can normally walk, and continual cure recovers normal a course for the treatment of on inspection substantially.
Case 2: grandson, female, 48 years old.Symptom: the strong pain of cervical region before 20 days, numbness of the fingers, heavy time light time dizzy, light Shi Ruyi ordinary person, very dizzy time heavy.Diagnosis: hyperosteogeny of cervical vertebra; Treatment: heat clearing away relaxing muscles and tendons, promoting blood circulation to remove obstruction in the collateral; The application of the invention emplastrum (according to the preparation of embodiment 2 method) treats a course for the treatment of, and patient is dizzy obviously to be alleviated.Continue a course for the treatment of of use again, patient's cervical region by force pain disappears, and range of motion obviously improves.Continue to strengthen a course for the treatment of, patient recovers normal substantially on inspection.
Case 3: Lee, female, 48 years old, people from Shandong, first visit on May 14 in 2007.Main suit: the right gonalgia 5 years, increases the weight of 3 years.Medical history: started before 5 years to occur the right gonalgia, local is afraid of cool, and the cloudy day increases the weight of whenever, and in March, 2006 takes the photograph sheet and shows: knee joint hyperosteogeny, though seek medical advice everywhere in recent years, force on, western medicines in treatment does not all alleviate, examine on May 14th, 2007, deep-thready pulse, light red tongue.Diagnosis: 1. right knee joint hyperosteogeny 2. rheumatic arthritis.Treatment: after detailed inspection, gives patient for patient's practical situation and takes Tablets (according to the preparation of embodiment 3 method), every day three times, each 2.After taking two courses for the treatment of, pain disappears completely.Continue to strengthen again treatment one month, recover normal on inspection completely
Following embodiment all can realize the effect of above-mentioned experimental example.
Detailed description of the invention
Embodiment 1 capsule
By said medicine conveniently technique add customary adjuvant and make capsule.Every day three times, each 2.
Embodiment 2 emplastrum
By said medicine conveniently technique add customary adjuvant and make emplastrum.Every day 1 pastes.
Embodiment 3 tablet
By said medicine conveniently technique add customary adjuvant and make tablet.Every day three times, each 2.
Embodiment 4 ointment
By said medicine conveniently technique add customary adjuvant and make ointment.
Embodiment 5 granule
By said medicine conveniently technique add customary adjuvant and make granule.
Embodiment 6 spray
By said medicine conveniently technique add customary adjuvant and make spray.
Claims (7)
1. treat a Chinese medicine composition for hyperosteogeny, it is characterized in that, the crude drug of said composition consists of:
2. Chinese medicine composition as claimed in claim 1, it is characterized in that, the crude drug of said composition consists of:
3. Chinese medicine composition as claimed in claim 1, it is characterized in that, the crude drug of said composition consists of:
4. Chinese medicine composition as claimed in claim 1, it is characterized in that, the crude drug of said composition consists of:
5. the Chinese medicine composition as described in one of claim 1-4, it is characterized in that said composition conveniently technique add customary adjuvant and make the tablet of clinical acceptance, capsule, granule, pill, oral liquid, emplastrum, spray, ointment, liniment or tincture.
6. the application of the Chinese medicine composition as described in one of claim 1-4 in the medicine of preparation treatment hyperosteogeny.
7. the application of Chinese medicine composition as claimed in claim 6 in the medicine of preparation treatment hyperosteogeny, is characterized in that described hyperosteogeny refers to hyperosteogeny of cervical vertebra, lumbar vertebra hyperosteogeny or knee joint hyperosteogeny.
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| CN104623476A (en) * | 2015-01-15 | 2015-05-20 | 李兆瑞 | Traditional Chinese medicine composition for treating osteoproliferation |
| CN106266029A (en) * | 2015-06-04 | 2017-01-04 | 贵州中草医医院 | A kind of Chinese medicine composition treating prolapse of lumbar intervertebral disc, hyperosteogeny |
| CN106266271A (en) * | 2016-09-08 | 2017-01-04 | 佛山市顺德区宝铜金属科技有限公司 | A kind of Chinese medicine composition treating cervical spondylosis |
| CN106729587A (en) * | 2017-03-02 | 2017-05-31 | 冷桂英 | Treatment osteoproliferation, lumbar vertebra protrusion, the externally applied drug of spinal canal stenosis and application method |
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| CN1425431A (en) * | 2002-12-18 | 2003-06-25 | 袁利亭 | Bone marrow recovery medicine |
| CN1788754A (en) * | 2004-12-13 | 2006-06-21 | 河北省中医药研究院高血压糖尿病研究所 | Oral medicine for treating hyperosteogeny-pellet for treating bone pain |
| CN102166277A (en) * | 2011-03-31 | 2011-08-31 | 谢子俊 | Waist healing pill |
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| KR101219295B1 (en) * | 2005-10-31 | 2013-01-14 | (주)아모레퍼시픽 | Composition for Promoting Production of Hyaluronic Acid Containing Musk T |
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Patent Citations (3)
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|---|---|---|---|---|
| CN1425431A (en) * | 2002-12-18 | 2003-06-25 | 袁利亭 | Bone marrow recovery medicine |
| CN1788754A (en) * | 2004-12-13 | 2006-06-21 | 河北省中医药研究院高血压糖尿病研究所 | Oral medicine for treating hyperosteogeny-pellet for treating bone pain |
| CN102166277A (en) * | 2011-03-31 | 2011-08-31 | 谢子俊 | Waist healing pill |
Non-Patent Citations (1)
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