CN103520498B

CN103520498B - Chinese medicinal composition for treating cerebral arteriosclerosis neurasthenia syndrome

Info

Publication number: CN103520498B
Application number: CN201310491607.XA
Authority: CN
Inventors: 李宪锋; 艾洪艳
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-10-11
Filing date: 2013-10-11
Publication date: 2015-06-24
Anticipated expiration: 2033-10-11
Also published as: CN103520498A

Abstract

The invention discloses a Chinese medicinal composition for treating cerebral arteriosclerosis neurasthenia syndrome. The traditional Chinese medicine doctors think that the syndrome is caused by the deficiency of vitality, yin-fluid and blood, and moistening and nourishing in muscle and vessel or heart and kidney, emptiness of brain, dysfunction of the spleen in transport and the like. According to the Chinese medicinal composition, the Chinese medicines including conic gymnadenia tuber, swallowwort herb, hemipilia, medicinal indianmulberry roots, harbenaria herbs, curious kadsura fruits, rhizoma tupistrae chinensis, rust-brown crotalaria, sago leaf, African marigold, Indian scutellaria and rhodobryum, which have the functions of replenishing qi and invigorating the spleen, tonifying the liver and kidney, invigorating the circulation of the tires and dredging collaterals, are decocted with water to prepare decoction; the clinical test shows that the total effective rate is up to 95.0 percent, and the Chinese medicinal composition is obviously superior to that of a control group; moreover, the Chinese medicinal composition is low in side effects and the adverse reaction is avoided after patients orally take the medicines.

Description

A kind of Chinese medicine composition for the treatment of cerebral arteriosclerosis neurasthenia syndrome

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of cerebral arteriosclerosis neurasthenia syndrome.

Background technology

Cerebral arteriosclerosis, can cause cerebral ischemia, brain atrophy, or causes rupture of blood vessel in brain hemorrhage.The commitment of cerebral arteriosclerosis can cause neurasthenia, and emotion is abnormal, and judgement is low.Cerebral arteriosclerosis can occur when reaching middle and late stage that gait is stiff or walking is unstable, dull-witted, epileptic convulsion, apoplexy.Cerebral arteriosclerosis neurasthenia syndrome is because cerebral arteriosclerosis causes neuron degeneration, necrosis, glial cells hyperplasia, finally produces disordered brain function syndrome, clinical manifestation mainly contains giddy, headache, insomnia, forgetful, difficult concentrating, anxiety, anxiety, agitation, tired, work efficiency reduces, fearness sound, tinnitus, general malaise and lethargy etc.Can with vegetative nerve and sexual disorder.At present, treat this sick doctor trained in Western medicine and also lack more satisfactory method, applicant, through clinical trial for many years, utilizes this disease for the treatment of by Chinese herbs to achieve good effect.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine composition for the treatment of cerebral arteriosclerosis neurasthenia syndrome.Primary disease belongs to Chinese medicine " dizzy ", " headache " category, and the traditional Chinese medical science thinks that unit of the primary disease system deficiency of vital energy declines, and cloudy anemia is damaged, and muscle arteries and veins loses it and moistens foster, or heart deficiency of the kidney is damaged, and brain is hollow, caused by the reasons such as dysfunction of the spleen in transportation.Primary disease is the card of vital QI being weakened and pathogen being violent, controls suitable giving consideration to both the incidental and fundamental, with replenishing QI to invigorate the spleen, liver and kidney tonifying, the tired dredging collateral of invigorating blood circulation for the rule for the treatment of.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment cerebral arteriosclerosis neurasthenia syndrome is made up of the Chinese medicine of following weight portion: Rhizoma Gymnadeniae 9-15 part, Radix Tylophorae arenicolae 15-25 part, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 20-25 part, Radix Morindae Officinalis 5-15 part, Herba Habenariae rhodochellae 10-20 part, Fructus Kadsurae heteroclitae 10-15 part, Rhizoma Tupistrae Chinensis 8-16 part, Herba Crotalariae Ferrugineae 35-45 part, Folium Cycadis Revolute 15-25 part, Flos Tagetis Erectae 5-15 part, Herba Scutellariae indicae 12-20 part, Rhodobryum giganteum(Hook.) Par. 10-20 part.

Preferred: Rhizoma Gymnadeniae 12 parts, Radix Tylophorae arenicolae 20 parts, a leaf obtain 23 parts, Radix Morindae Officinalis 10 parts, Herba Habenariae rhodochellae 15 parts, Fructus Kadsurae heteroclitae 12 parts, Rhizoma Tupistrae Chinensis 13 parts, Herba Crotalariae Ferrugineae 40 parts, Folium Cycadis Revolute 20 parts, Flos Tagetis Erectae 10 parts, Herba Scutellariae indicae 15 parts, Rhodobryum giganteum(Hook.) Par. 16 parts.

Above-mentioned Chinese medicine decocting is made decoction by preparation method.

Fang Zhong: Rhizoma Gymnadeniae strengthening by means of tonics, spleen reinforcing lung moistening, calms the nerves relieving convulsion, QI invigorating pain relieving; Radix Tylophorae arenicolae kidney and spleen invigorating, removing toxic substances; One leaf obtains relaxing muscles and tendons to promote blood circulation, tonifying speen and tonifying kidney; Radix Morindae Officinalis, Herba Habenariae rhodochellae kidney-replenishing, wind-damp dispelling; The kidney invigorating of Fructus Kadsurae heteroclitae heart tonifying, eliminating phlegm and stopping cough; Rhizoma Tupistrae Chinensis nourishing yin and promoting blood circulation; Herba Crotalariae Ferrugineae invigorating the spleen and replenishing QI, diuretic antiinflammatory; Folium Cycadis Revolute vital energy regualting and blood circulation-promoting suppressing the hyperactive liver; Flos Tagetis Erectae is enriched blood and is stimulated the menstrual flow, promoting tissue regeneration by removing blood stasis; Herba Scutellariae indicae dispels the wind, and invigorates blood circulation, removing toxic substances, pain relieving; Rhodobryum giganteum(Hook.) Par. tranquillizing and allaying excitement, clear away heart-fire improving eyesight.

Clinical data

1. physical data is originally organized 120 examples and is out-patient, by table of random number, case stochastic averagina is divided into treatment group and matched group.Treatment group 60 example, man 35 example, female 25 example, 43 ~ 70 years old age, average 55.1 years old, the course of disease 2 months ~ 9 years.Matched group 60 example, man 37 example, female 23 example, 45 ~ 73 years old age, average 56.3 years old, the course of disease 2 months ~ 10 years.Two groups of patients compare in sex, age, the course of disease, and no significant difference (P>0.05), has comparability.

2. diagnostic criteria is with reference to " the cerebral arteriosclerosis diagnostic criteria " of the 3rd the psychoneural section academic conference revision in the whole nation in 1981, in conjunction with the armarium situation of my institute, formulate following diagnostic criteria: (1) has the clinical manifestation of neurasthenia's disease group, as dizzy, headache, one's ears rang and spots danced before one's eyes, fatigue and weakness, forgetful agitation, bradyphrenia, sleep disorder; (2) more than ocular fundus arteriosclerosis II level; (3) serum cholesterol and triglyceride increase; (4) transcranial doppler (TCD) shows cerebral arteriosclerosis; (5) in conjunction with CT scan, except can cause other disease of brain of similar clinical manifestation.

3. Therapeutic Method treatment group patient takes Chinese medicine composition of the present invention, take Rhizoma Gymnadeniae 12g, Radix Tylophorae arenicolae 20g, a leaf obtain 23g, Radix Morindae Officinalis 10g, Herba Habenariae rhodochellae 15g, Fructus Kadsurae heteroclitae 12g, Rhizoma Tupistrae Chinensis 13g, Herba Crotalariae Ferrugineae 40g, Folium Cycadis Revolute 20g, Flos Tagetis Erectae 10g, Herba Scutellariae indicae 15g, Rhodobryum giganteum(Hook.) Par. 16g, decocting becomes decoction, every day potion, dividing and sooner or later take for 2 times, 14th is 1 course for the treatment of; Matched group oral vitamin E0.1g, every day 3 times, nimodipine 20mg, every day 3 times, piracetam 0.8g, every day 3 times; Two groups all serve on 4 courses for the treatment of.

4. criterion of therapeutical effect is by the standard rating curative effect in " guideline of clinical investigations of new Chinese medicine treatment cerebral arteriosclerosis ".Cure: primary symptom disappears, the main Index for examination result such as TCD, blood fat, optical fundus is normal; Effective: primary symptom integration reduces by more than 70%, TCD and obviously improves, and blood fat obviously declines; Effective: primary symptom integration reduces 36%-69%, TCD and has some improvement, rate and blood-lipid decreased; Invalid: not reach above-mentioned effective standard.

5. therapeutic effect two groups treats comparitive study after 4 courses for the treatment of, and treatment group 60 example, wherein cures 35 examples (58.3%); Effective 15 examples (25.5%), effective 7 examples (11.7%), invalid 3 examples (5.0%), total effective rate 95.0%; Matched group 60 example, wherein cures 18 examples (30.0%); Effective 20 examples (33.3%), effective 11 examples (18.3%), invalid 11 examples (18.3%), total effective rate 81.7%.Two groups are compared, and treatment group cure rate, total effective rate are obviously better than matched group, have comparability.P<0.05。

Detailed description of the invention

Embodiment one: take Rhizoma Gymnadeniae 12g, Radix Tylophorae arenicolae 20g, a leaf obtains 23g, Radix Morindae Officinalis 10g, Herba Habenariae rhodochellae 15g, Fructus Kadsurae heteroclitae 12g, Rhizoma Tupistrae Chinensis 13g, Herba Crotalariae Ferrugineae 40g, Folium Cycadis Revolute 20g, Flos Tagetis Erectae 10g, Herba Scutellariae indicae 15g, Rhodobryum giganteum(Hook.) Par. 16g, becomes decoction by above-mentioned Chinese medicine decocting.

Embodiment two: take Rhizoma Gymnadeniae 15g, Radix Tylophorae arenicolae 25g, a leaf obtains 20g, Radix Morindae Officinalis 15g, Herba Habenariae rhodochellae 10g, Fructus Kadsurae heteroclitae 15g, Rhizoma Tupistrae Chinensis 8g, Herba Crotalariae Ferrugineae 45g, Folium Cycadis Revolute 25g, Flos Tagetis Erectae 5g, Herba Scutellariae indicae 20g, Rhodobryum giganteum(Hook.) Par. 10g, becomes decoction by above-mentioned Chinese medicine decocting.

Embodiment three: take Rhizoma Gymnadeniae 9g, Radix Tylophorae arenicolae 15g, a leaf obtains 25g, Radix Morindae Officinalis 5g, Herba Habenariae rhodochellae 20g, Fructus Kadsurae heteroclitae 10g, Rhizoma Tupistrae Chinensis 16g, Herba Crotalariae Ferrugineae 35g, Folium Cycadis Revolute 15g, Flos Tagetis Erectae 15g, Herba Scutellariae indicae 12g, Rhodobryum giganteum(Hook.) Par. 20g, becomes decoction by above-mentioned Chinese medicine decocting.

Claims

1. treat the Chinese medicine composition of cerebral arteriosclerosis neurasthenia syndrome for one kind, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight: Rhizoma Gymnadeniae 12g, Radix Tylophorae arenicolae 20g, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 23g, Radix Morindae Officinalis 10g, Herba Habenariae rhodochellae 15g, Fructus Kadsurae heteroclitae 12g, Rhizoma Tupistrae Chinensis 13g, Herba Crotalariae Ferrugineae 40g, Folium Cycadis Revolute 20g, Flos Tagetis Erectae 10g, Herba Scutellariae indicae 15g, Rhodobryum giganteum(Hook.) Par. 16g, become decoction by above-mentioned Chinese medicine decocting.