CN102579941B - Drug for treating lumbar intervertebral disc herniation with pain as well as preparation method of oral liquid of drug - Google Patents

Drug for treating lumbar intervertebral disc herniation with pain as well as preparation method of oral liquid of drug Download PDF

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CN102579941B
CN102579941B CN 201210087595 CN201210087595A CN102579941B CN 102579941 B CN102579941 B CN 102579941B CN 201210087595 CN201210087595 CN 201210087595 CN 201210087595 A CN201210087595 A CN 201210087595A CN 102579941 B CN102579941 B CN 102579941B
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intervertebral disc
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沈卫强
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Abstract

The invention discloses a drug for treating lumbar intervertebral disc herniation with pain. The drug consists of the following ingredients in portions by weight: 20-40 portions of carthamus tinctorius, 20-40 portions of cortex acanthopanacis, 10-30 portions of rhizoma alpiniae officinarum, 10-20 portions of Chinese angelica, 20-30 portions of caulis sinomenii, 20-40 portions of erythrina bark, 20-30 portions of rhizoma corydalis, 20-30 portions of codonopsis pilosula, 10-20 portions of cortex lycii radicis, 10-30 portions of radix aucklandiae, 20-40 portions of salvia miltiorrhiza, 20-40 portions of caulis trachelospermi, 10-20 portions of radix stephaniae tetrandrae, 20-40 portions of ligusticum wallichii, 10-30 portions of salt eucommia, 20-40 portions of cortex ailanthi, 20-40 portions of achyranthes bidentata, 20-40 portions of poria cocos, 20-40 portions of caulis piperis futokadsurae, 20-40 portions of radix clematidis and 10-20 portions of herba epimedii. The above medicines are added to 5000 portions of 30-40 DEG liquor to be sealed and stored for one month, and the liquor containing traditional Chinese medicine is poured out after dregs are removed. The curative effect of the drug is better than the curative effects of acupuncture and moxibustion, massage, acupoint injection and other traditional Chinese medicines.

Description

A kind of medicine of prolapse of lumbar intervertebral disc companion pain and manufacture method of oral liquid thereof for the treatment of
Technical field
The present invention relates to a kind of medicine for the treatment of prolapse of lumbar intervertebral disc companion pain.
Background technology
Saying that from the doctor trained in Western medicine angle lumbar intervertebral disc is one of regression organ the earliest human body, approximately start from 20 years old, is the irreversible degenerative change process that occurred by various factors.The intervertebral disc of regression is due to the degraded of vertebral pulp proteoglycan, and polywater reduces, and its renitent ability reduces; The collagen protein composition changes weakens the ability of its compensator or trimmer pressure, opposing tension force, and the two combined effect meeting reduces intervertebral disc and absorbs load, the mechanics function of dispersive stress.On the basis of intervertebral disc biochemical composition regression, biomechanical function is lost or is weakened and causes fibrous ring to occur such as crack, fracture a series of variations such as even break occurring, finally cause vertebral pulp outstanding, compressing and stimulation spinal cord, nerve root, produce the lumbago and skelalgia sings and symptoms.
See that from the traditional Chinese medical science angle prolapse of lumbar intervertebral disc belongs to the category of Chinese medicine " arthromyodynia ", " lumbago ", endogenous cause of ill mostly is innate deficiency, and Liver and kidney is deficient, weakness due to chronic disease; Exopathogenic factor mostly is wind-cold damp pathogen, labor of a specified duration, and the sprain and contusion strain, cause the meridians impatency, caused by energy stagnation and blood stasis.
Treatment on the traditional Chinese medical science at present has acupuncture, massage, acupoint injection therapy, the side of taking traditional Chinese medicine, and only has the part patient with slight symptoms effective, and also there are certain contraindication in wherein acupuncture, massage, acupoint injection therapy, and Waiting time is long, takes a turn for the better slowly; The doctor trained in Western medicine initial stage take have a rest and functional exercise as main, along with aggravation is just selected some anti-inflammatory analgetic class medicines, it exists side effect such as harmonization of the stomach kidneys, finally consider operation, certainly risk is larger, well imagine that for its risk of patient that merges other diseases the patient of many poor effect and Relapse rate is also arranged after operation.Wasted a lot of financial resources and also wasted a lot of energy, health has been caused to very large impact.
Summary of the invention
The invention provides a kind of medicine for the treatment of prolapse of lumbar intervertebral disc companion pain and the manufacture method of oral liquid thereof, that utilizes Chinese medicine to solve that prolapse of lumbar intervertebral disc causes allows the insufferable pain of people, the various side effect of avoiding using Western medicine or modus operandi to bring to the people and potential larger complication and can not utilize the mode such as operation to solve the problem of Principle of Pain.
In order to realize the foregoing invention purpose, a kind of medicine for the treatment of prolapse of lumbar intervertebral disc companion pain is comprised of following component by weight:
Figure BDA0000148221020000021
A kind of manufacture method for the treatment of the medicine oral liquid of prolapse of lumbar intervertebral disc companion pain, first prepare by weight ratio following component:
Figure BDA0000148221020000022
Then above 21 kinds of medicines are added in the Chinese liquor (edible ethanol) of 30-40 degree of 5000 parts (weight ratios) to Seal and preservation January, remove slag and pour out the wine that contains Chinese medicine and get final product.Its instructions of taking is 10-15ml/ time, and 2 times/days, first quarter moon is a course for the treatment of, and general medication is the 3-5 course for the treatment of, and patient generally has positive effect after half course for the treatment of of medication.
The present invention is according to the pathogenesis etiology pathology of prolapse of lumbar intervertebral disc, and by dispelling wind and removing dampness, stimulate the menstrual flow, invigorate blood circulation, circulation of qi promoting, pain relieving, invigorating the liver and kidney, the way of bone and muscle strengthening is nursed one's health the purpose that reaches healing.Wherein the effect of each component is as follows:
1) effect of Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.
2) effect of Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation, can the dispelling the wind and dampness pathogens arthralgia pain.
3) effect of Rhizoma Corydalis: invigorate blood circulation, promoting the circulation of QI, pain relieving.
4) effect of the Radix Aucklandiae: 1, promoting the circulation of QI to relieve pain 2, soothing the liver 3, the spleen invigorating of regulating the flow of vital energy disappear stagnant.
5) effect of Radix Stephaniae Tetrandrae: row water, rush down damp-heat in lower-JIAO.Analgesic activity is also arranged.
6) effect of Cortex Ailanthi and effect: heat clearing and damp drying, astringent therapy leukorrhagia stopping, antidiarrheal, hemostasis.
7) effect of Caulis Piperis Kadsurae: wind-damp dispelling, the meridian dredging, regulate the flow of vital energy.Control anemofrigid-damp arthralgia, arthralgia, the contracture of muscle arteries and veins.
8) effect of Cortex Acanthopancis: wind-damp dispelling, strengthening bone and muscle, blood circulation and promoting silt.Control anemofrigid-damp arthralgia, the muscles and bones contraction is anxious, lumbago.
9) effect that bluish glaucoma is risen: wind-damp dispelling, the meridian dredging, diuresis.For rheumatic arthralgia.
10) effect of Radix Codonopsis: the spleen reinforcing lung qi, enrich blood, promote the production of body fluid.
11) effect of Radix Salviae Miltiorrhizae: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.
12) effect of Rhizoma Chuanxiong: hot loose temperature is logical, the function blood circulation promoting and blood stasis dispelling.
13) effect of Radix Achyranthis Bidentatae: invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation.
14) effect of Radix Clematidis: wind-damp dispelling, removing obstruction in the collateral to relieve pain, a fishbone or other bone caught in the throat disappears.
15) effect of Rhizoma Alpiniae Officinarum: stomach warming, dispel the wind, cold expelling, circulation of qi promoting, pain relieving.
16) effect of Cortex erythrinae: wind-damp dispelling, the meridian dredging.
17) effect of Cortex Lycii: clearing away heat and cooling blood has simultaneously and mends the internal injury great Lao suction of hissing, hard muscle, the effect of reinforcing YIN-essence.
18) effect of Caulis Trachelospermi: dispel the wind, dredging collateral, hemostasis, repercussive.
19) effect of Cortex Eucommiae(processed with salt): invigorating the liver and kidney, bone and muscle strengthening.
20) effect of Poria: eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.
21) effect of Herba Epimedii: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.
The mechanism of action of medicine:
1, wind-damp dispelling, the meridian dredging: contain in medicine that Caulis Piperis Kadsurae, Cortex Acanthopancis, bluish glaucoma rise, Radix Clematidis, Cortex erythrinae, Caulis Trachelospermi all have and dispel wind and remove dampness, live through the effect of dredging collateral.Actively remove the exopathogenic factor of disease.
2, invigorate blood circulation, circulation of qi promoting, pain relieving: containing Flos Carthami, Radix Angelicae Sinensis, Rhizoma Corydalis, the Radix Aucklandiae, Radix Stephaniae Tetrandrae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Rhizoma Alpiniae Officinarum in medicine all has blood circulation promoting and blood stasis dispelling, circulation of qi promoting, the effect of pain relieving, can actively treat the meridians obturation that labor sitting of a specified duration causes, the qi depression to blood stasis situation.Improve patient's pain symptom.
3, invigorating the liver and kidney, bone and muscle strengthening: contain Radix Achyranthis Bidentatae, Cortex Eucommiae(processed with salt), Herba Epimedii in medicine and have invigorating the liver and kidney, the effect of bone and muscle strengthening, can be effectively deficient for Liver and kidney, utilizes Radix Codonopsis spleen reinforcing lung qi simultaneously, controls its body void.The endogenous cause of ill of active treatment disease.
The present invention is according to theory of Chinese medical science, dialectical treating, and the theory for the treatment of both the principal and secondary aspects of a disease, reach the purpose of curing the state of an illness.Product of the present invention is easy to use, inexpensive, good effect, can significantly improve and remove pain symptom, uses not find the side effect under routine dose.Its curative effect obviously is better than acupuncture, massage, acupoint injection therapy and other Chinese medicine, and the not in place and local damage that causes or increase the weight of of can also avoiding having a fainting spell during acupuncture treatment, infect and massage; Compare the various side effect that there is no anti-inflammatory analgetic class medicine with Western medicine, compare with operation and more can embody its huge advantage, not only avoid damage, the operation risk of health, but also reduce expenses.
The specific embodiment
Getting following medication amount is prepared:
Figure BDA0000148221020000041
Figure BDA0000148221020000051
Then above medicine is added to Seal and preservation January in the Chinese liquor of 38 degree of 5kg, remove slag and pour out the wine that contains Chinese medicine and obtain oral liquid.
Case 1, patient king so-and-so, the female, 59 years old, the peasant, body is strong usually, the major disease histories such as acardia, liver, kidney, without hypertension and diabetes.Lumbago is more than 3 years repeatedly, then sends out and increase the weight of to accompany left lower extremity radiating pain January.Difficulty in walking, bed.2 years causes will bitterly be accompanied left lower extremity radiating pain row lumbar vertebra MRI to check and are diagnosed as waist 3-4, waist 4-5 intervertebral disk hernia.The row surgical operation therapy.This time send out again, successively, more than Zhejiang doctor's hospital orthopedics and Fuyang orthopedics department hospital admission treatment first quarter moon, without taking a turn for the better, consider that again operation risk is very large, start to take this product, a 15ml, 2 times on the one, after 1 week, symptom is clearly better, freedom of movement after 2 weeks, serve on March, and show effect without pain inactive March always.
Case 2, patient Liu so-and-so, the female, 66 years old, the peasant, body is strong usually, the major disease histories such as acardia, liver, kidney, without hypertension and diabetes.Lumbago is more than 2 years repeatedly, then sends out and increase the weight of to accompany left lower extremity radiating pain first quarter moon.Walk and walk lamely, through lumbar vertebra MRI, check and be diagnosed as waist 4-5 intervertebral disk hernia, suggestion operative treatment after orthopaedics is medical, but consider the operation risk expense.Start to take this product, a 10ml, 2 times on the one, after 1 week, symptom is clearly better, and after 2 weeks, basic the disappearance, serve on more than February, and show effect without pain inactive February always.
Case 3, patient Shen so-and-so, the female, 57 years old, the peasant, body is strong usually, the major disease histories such as acardia, liver, kidney, have hypertension and diabetic history.Lumbago is more than 4 years repeatedly, then sends out and increase the weight of to accompany the right lower extremity radiating pain 1 week.Walk and walk lamely, check and be diagnosed as waist 4-5 intervertebral disk hernia after orthopaedics is medical, surgical indication is arranged, because of the existence foundation disease through lumbar vertebra MRI, consider that operation risk is very large, start to take this product, a 10ml, 2 times on the one, after 1 week, symptom is clearly better, after 4 weeks, basic the disappearance, serve on May, and show effect without pain inactive January always.
Case 4, patient side certain, the female, 62 years old, the peasant, body is strong usually, the major disease histories such as acardia, liver, kidney, without hypertension and diabetic history.There is rheumatic arthritis for many years.Lumbago is more than 5 years repeatedly, then sends out and increase the weight of to accompany the left lower extremity radiating pain 1 week.Often acupuncture, physical therapy, take traditional Chinese medicine.Once the lumbar vertebra CT examination of going is diagnosed as waist 4-5 intervertebral disk hernia.Onset after this time bearing a heavy burden, walk and walk lamely, and the patient takes this product, a 15ml, and 2 times on the one, after 4 days, symptom is clearly better, and after 1 week, walking is freely.Serve on March, show effect without pain inactive February always.
Case 5, patient Wu so-and-so, the female, 58 years old, the peasant, body is strong usually, the major disease histories such as acardia, liver, kidney, have hypertension and cerebral infarction medical history.Lumbago is more than 3 years repeatedly, then sends out and increase the weight of to accompany the right lower extremity radiating pain 2 weeks.Walk and walk lamely, through lumbar vertebra MRI, check and be diagnosed as waist 4-5 intervertebral disk hernia.The patient takes this product, a 10ml, and 2 times on the one, after 1 week, symptom is clearly better, and after 3 weeks, basic the disappearance, serve on March, and show effect without pain inactive March always.
Case 6, patient Jiang, the man, 56 years old, the peasant, body is strong usually, and the major disease histories such as acardia, liver, kidney, without hypertension and diabetic history.Lumbago is more than 5 years repeatedly, then sends out and increase the weight of to accompany the right lower extremity radiating pain 1 week.Often acupuncture, massage treatment at ordinary times.Check and be diagnosed as waist 4-5 intervertebral disk hernia through lumbar vertebra MRI, can operative treatment after orthopaedics is medical.The patient takes this product, a 15ml, and 2 times on the one, after 3 days, symptom takes a turn for the better, and after 2 weeks, basic the disappearance, serve on February, and show effect without pain inactive April always.

Claims (2)

1. treat the medicine that prolapse of lumbar intervertebral disc is accompanied pain for one kind, it is characterized in that: formed by following component by weight:
Figure FDA0000148221010000011
2. a manufacture method for the treatment of the medicine oral liquid of prolapse of lumbar intervertebral disc companion pain, is characterized in that, first prepares by weight ratio following component:
Figure FDA0000148221010000012
Then above 21 kinds of medicines are added in the Chinese liquor of 30-40 degree of 5000 parts to Seal and preservation January, remove slag and pour out the wine that contains Chinese medicine and get final product.
CN 201210087595 2012-03-29 2012-03-29 Drug for treating lumbar intervertebral disc herniation with pain as well as preparation method of oral liquid of drug Expired - Fee Related CN102579941B (en)

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强直性脊柱炎的中药治疗近况;柴晟等;《广西中医学院学报》;20060331;第9卷(第3期);88-89页 *
柴晟等.强直性脊柱炎的中药治疗近况.《广西中医学院学报》.2006,第9卷(第3期),

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