CN103509118B - 胰岛素-Fc融合蛋白 - Google Patents
胰岛素-Fc融合蛋白 Download PDFInfo
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- CN103509118B CN103509118B CN201210198941.1A CN201210198941A CN103509118B CN 103509118 B CN103509118 B CN 103509118B CN 201210198941 A CN201210198941 A CN 201210198941A CN 103509118 B CN103509118 B CN 103509118B
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CN201210198941.1A CN103509118B (zh) | 2012-06-15 | 2012-06-15 | 胰岛素-Fc融合蛋白 |
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CN201210198941.1A CN103509118B (zh) | 2012-06-15 | 2012-06-15 | 胰岛素-Fc融合蛋白 |
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CN103509118A CN103509118A (zh) | 2014-01-15 |
CN103509118B true CN103509118B (zh) | 2016-03-23 |
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CN201210198941.1A Active CN103509118B (zh) | 2012-06-15 | 2012-06-15 | 胰岛素-Fc融合蛋白 |
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Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20130049671A (ko) | 2011-11-04 | 2013-05-14 | 한미사이언스 주식회사 | 생리활성 폴리펩타이드 결합체 제조 방법 |
AR090281A1 (es) | 2012-03-08 | 2014-10-29 | Hanmi Science Co Ltd | Proceso mejorado para la preparacion de un complejo polipeptidico fisiologicamente activo |
WO2015152618A1 (ko) * | 2014-03-31 | 2015-10-08 | 한미약품 주식회사 | 면역글로불린 fc 단편 결합을 이용한 단백질 및 펩타이드의 용해도를 개선시키는 방법 |
US10894089B2 (en) | 2015-02-17 | 2021-01-19 | Hanmi Pharm. Co., Ltd. | Long-acting insulin or insulin analogue conjugate |
WO2016161983A1 (zh) * | 2015-04-10 | 2016-10-13 | 中国医学科学院药物研究所 | 一种融合载体蛋白及其在促进目的蛋白或多肽表达中的应用 |
AR105616A1 (es) | 2015-05-07 | 2017-10-25 | Lilly Co Eli | Proteínas de fusión |
LT3551209T (lt) * | 2016-12-09 | 2021-09-10 | Akston Biosciences Corporation | Insulino-fc suliejimai ir panaudojimo būdai |
HUE058005T2 (hu) | 2018-06-29 | 2022-06-28 | Akston Biosciences Corp | Ultra hosszan ható inzulin Fc fehérjék, és alkalmazási eljárások |
US11267862B2 (en) | 2018-06-29 | 2022-03-08 | Akston Biosciences Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
KR102114275B1 (ko) * | 2018-11-07 | 2020-05-25 | 제주대학교 산학협력단 | C-펩타이드를 유효성분으로 포함하는 미세먼지에 대한 피부보호용 화장료 조성물 |
WO2021011827A1 (en) * | 2019-07-16 | 2021-01-21 | Akston Biosciences Corporation | Ultra-long acting insulin-fc fusion proteins and methods of use |
TW202120536A (zh) | 2019-07-31 | 2021-06-01 | 美商美國禮來大藥廠 | 鬆弛素(relaxin)類似物及其使用方法 |
US11186623B2 (en) | 2019-12-24 | 2021-11-30 | Akston Bioscience Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
CN111000982A (zh) * | 2019-12-25 | 2020-04-14 | 沣潮医药科技(上海)有限公司 | Amhr2重组蛋白或融合蛋白在制备amh信号轴异常活化相关疾病治疗药物中的用途 |
IL297064A (en) | 2020-04-10 | 2022-12-01 | Akston Biosciences Corp | Antigen-specific immunotherapy for covid-19 fusion proteins and methods of use |
US11192930B2 (en) | 2020-04-10 | 2021-12-07 | Askton Bioscences Corporation | Ultra-long acting insulin-Fc fusion protein and methods of use |
EP4230216A1 (en) | 2020-07-24 | 2023-08-23 | Jiangsu Gensciences Inc. | Insulin-fc fusion protein and application thereof |
EP4373861A2 (en) | 2021-07-23 | 2024-05-29 | Akston Biosciences Corporation | Insulin-fc fusion proteins and methods of use to treat cancer |
TW202339790A (zh) | 2021-11-15 | 2023-10-16 | 美商美國禮來大藥廠 | 可保存之調配物 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008019368A2 (en) * | 2006-08-07 | 2008-02-14 | Teva Biopharmaceuticals Usa, Inc. | Albumin-insulin fusion proteins |
WO2011053763A2 (en) * | 2009-10-30 | 2011-05-05 | Centocor Ortho Biotech Inc. | Il-17a antagonists |
CN102070717A (zh) * | 2009-11-19 | 2011-05-25 | 东莞太力生物工程有限公司 | 融合蛋白及其制备方法、编码该蛋白的dna序列、表达载体、宿主细胞、含有该蛋白的药物组合物 |
CN102256992A (zh) * | 2008-12-19 | 2011-11-23 | 印第安纳大学研究及科技有限公司 | 胰岛素类似物 |
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2012
- 2012-06-15 CN CN201210198941.1A patent/CN103509118B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008019368A2 (en) * | 2006-08-07 | 2008-02-14 | Teva Biopharmaceuticals Usa, Inc. | Albumin-insulin fusion proteins |
CN102256992A (zh) * | 2008-12-19 | 2011-11-23 | 印第安纳大学研究及科技有限公司 | 胰岛素类似物 |
WO2011053763A2 (en) * | 2009-10-30 | 2011-05-05 | Centocor Ortho Biotech Inc. | Il-17a antagonists |
CN102070717A (zh) * | 2009-11-19 | 2011-05-25 | 东莞太力生物工程有限公司 | 融合蛋白及其制备方法、编码该蛋白的dna序列、表达载体、宿主细胞、含有该蛋白的药物组合物 |
Non-Patent Citations (1)
Title |
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ACCESSION NO:AEV43323.1,Fc IgG1 heavy chain constant region,partial[Homo sapiens];Niranjana,K.R.P.,et al.;《Genbank database》;20111211;FEATURES, ORIGIN * |
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Effective date of registration: 20161223 Address after: 201203 Shanghai City, Pudong New Area hi tech Bing Road No. 301 Patentee after: Shanghai metech junao Biological Technology Co. Ltd. Address before: Shanghai city 201203 libing road Pudong New Area Zhangjiang hi tech Park No. 399 Patentee before: Guo Huaizu |
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Denomination of invention: Insulin-Fc fusion protein Effective date of registration: 20190322 Granted publication date: 20160323 Pledgee: Shanghai Baimai Pharmaceutical Co.,Ltd. Pledgor: Shanghai metech junao Biological Technology Co. Ltd. Registration number: 2019310000007 |
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Date of cancellation: 20210119 Granted publication date: 20160323 Pledgee: Shanghai Biomabs Pharmaceuticals Co.,Ltd. Pledgor: SHANGHAI MAITAI JUNAO BIOTECHNOLOGY Co.,Ltd. Registration number: 2019310000007 |
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