CN103495115B - A kind of to the medicative medicated wine of diabetes tool - Google Patents
A kind of to the medicative medicated wine of diabetes tool Download PDFInfo
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Abstract
The invention provides a kind of to the medicative medicated wine of diabetes tool, have following component at the wine of 3000 grams ~ 30000 grams: Radix Ginseng 30 grams ~ 100 grams; Fructus Lycii 100 grams ~ 300 grams; Fructus Mume 30 grams ~ 100 grams; Radix Polygalae 50 grams ~ 150 grams; Radix Platycodonis 30 grams ~ 100 grams; Radix Salviae Miltiorrhizae 50 grams ~ 250 grams; Radix Notoginseng 30 grams ~ 100 grams; Sanguis Draxonis 100 grams ~ 300 grams; Ganoderma 30 grams ~ 100 grams; 30 grams ~ 100 grams, Rhizoma Curcumae Longae; Radix Curcumae 50 grams ~ 150 grams.The present invention utilizes soaking in Chinese liquor Chinese medicine, Chinese medicine by soaking in Chinese liquor, utilizes the permeability that ethanol is superpower, residence medicine is in wine, and wine helps the property of medicine, greatly improves the practicality of Chinese medicine, dissolve a herbal nature difficult problem slowly, give full play to the guiding drug function of wine, strengthen targeting, this medicated wine is based on oral, this medicated wine manufacture method is simple, and raw material is easy to get, and cost is low, multiple functional, good effect.
Description
Technical field
The invention belongs to a kind of medicated wine of medical art, be specifically a kind of have auxiliary hyperglycemic effect to medicative medicated wine of diabetes tool and preparation method thereof.
Background technology
The sickness rate of current China diabetes up to 9.7%, number of patients about 9,700 ten thousand people, at present also with every day 3,000 example speed increase., according to World Health Organization's statistics display, the annual Diabetes Death number in the world is seven million peoples, and on average every ten seconds are with regard to a dead example, just have a diabetics every 30 seconds by amputation.The current ill total number of persons of China surmounts the U.S., and India becomes the first in the world.The method that diabetes not there is no radical cure as worldwide difficult medical problem so far because its pathogenesis is very complicated, especially complication, hard to guard against especially, fatality rate, the height of disability rate ranks front three.Show according to up-to-date diabetes study, the pathogenesis traditional Chinese medical science of diabetes is thought to be caused by human body deficiency of both QI and YIN from the Elevation Analysis of strategy, should be caused by the deficiency of vital energy more precisely, the deficiency of vital energy is only had just to match with " The Yellow Emperor's Canon of Internal Medicine " the five internal organs pathogenesis, according to " Huang di's Canon of Medicine ", " TCM basis theory ", " Chinese materia medica ", " Compendium of Materia Medica ", " diabetology " and other scientific theories are for instructing, in fact the traditional Chinese medical science has superiority in diabetes control, health therapy for diabetes and complication thereof can be solved by dietetic therapy, namely by studying on pure book on Chinese herbal medicine, collection food, health product, medicine integration, improve the prevention of Chinese medicine, health care, therapeutic effect.
According to diabetology research display, show have 54 kinds of Chinese herbal medicine to have hypoglycemic activity through zoopery, the Chinese medicine ending the treatment diabetes that in December, 2007 state food drug surveilance office examination & approval are promulgated amounts to 35 kinds, relate to pill, capsule, oral liquid, granule, tablet, injection 6 kinds of dosage forms, wherein only a kind of is the effective ingredient extracted from Chinese medicine.
Show according to up-to-date diabetology research, the Chinese medicinal plant composition with hypoglycemic activity mainly contains: terpenoid, insulin, peptide and amino acids, flavonoid, polysaccharide, thioether class, alkaloids, Coumarins and unsaturated fatty acids etc., they play curative effect by the approach do not allowed and target spot in the treatment of diabetes, but these effective chemicals, the destroyed goods of major part is inactivated under the high temperature conditions, get when in the high quality liquor at 50---53 degree ethanol content, room temperature is molten, the activity of these materials and concentration are then quite high, its hypoglycemic effect is poor unlike Western medicine, and toxic and side effects is little, and there is the effect effected a permanent cure.
Summary of the invention
According to above-mentioned elaboration, the object of the present invention is to provide and auxiliary therapeutic action is played to diabetictrunk angiopathy and can be hypoglycemic to the medicative a kind of medicated wine of diabetes tool.
A kind of technical scheme to the medicative medicated wine of diabetes tool provided by the invention, has following component at the wine of 3000 grams ~ 30000 grams:
Radix Ginseng 30 grams ~ 100 grams; Fructus Lycii 100 grams ~ 300 grams; Fructus Mume 30 grams ~ 100 grams; Radix Polygalae 50 grams ~ 150 grams; Radix Platycodonis 30 grams ~ 100 grams; Radix Salviae Miltiorrhizae 50 grams ~ 250 grams; Radix Notoginseng 30 grams ~ 100 grams; Sanguis Draxonis 100 grams ~ 300 grams; Ganoderma 30 grams ~ 100 grams; 30 grams ~ 100 grams, Rhizoma Curcumae Longae; Radix Curcumae 50 grams ~ 150 grams.
In the preferred version of such scheme, there is following component at the wine of 3000 grams ~ 30000 grams:
Radix Ginseng 40 grams ~ 80 grams; Fructus Lycii 150 grams ~ 250 grams; Fructus Mume 40 grams ~ 90 grams; Radix Polygalae 80 grams ~ 120 grams; Radix Platycodonis 40 grams ~ 80 grams; Radix Salviae Miltiorrhizae 100 grams ~ 200 grams; Radix Notoginseng 40 grams ~ 80 grams; Sanguis Draxonis 150 grams ~ 250 grams; Ganoderma 50 grams ~ 80 grams; 40 grams ~ 70 grams, Rhizoma Curcumae Longae; Radix Curcumae 80 grams ~ 120 grams.
In the preferred version of such scheme, there is following component at the wine of 3000 grams ~ 30000 grams:
Radix Ginseng 50 grams ~ 80 grams; Fructus Lycii 150 grams ~ 200 grams; Fructus Mume 50 grams ~ 80 grams; Radix Polygalae 100 grams ~ 120 grams; Radix Platycodonis 40 grams ~ 50 grams; Radix Salviae Miltiorrhizae 150 grams ~ 200 grams; Radix Notoginseng 40 grams ~ 50 grams; Sanguis Draxonis 150 grams ~ 200 grams; Ganoderma 50 grams ~ 70 grams; 40 grams ~ 70 grams, Rhizoma Curcumae Longae; Radix Curcumae 90 grams ~ 100 grams.
Described wine is the pure grain wine of 40 ~ 60 degree, as one of in corn wine, Sorghum vulgare Pers. Wine, buckwheat wine, little ale, barley broo.
Preparation method to the medicative medicated wine of diabetes tool provided by the invention is:
Described component inserted in the pure grain wine of 40 ~ 60 degree, room temperature sealing is placed 30-50 days.
The present invention utilizes soaking in Chinese liquor Chinese medicine, reach collection food, health product, the effect of medicine integration, Chinese medicine is passed through soaking in Chinese liquor, utilize the permeability that ethanol is superpower, residence medicine is in wine, wine helps the property of medicine, greatly improve the practicality of Chinese medicine, dissolve a herbal nature difficult problem slowly, give full play to the guiding drug function of wine, strengthen targeting, nutrient substance abundant in wild Chinese herbal medicine is separated out, collection edible wine, health promoting wine, treatment wine is in one, the pharmacy mode of the traditional Chinese medical science is constantly developed, this medicated wine is based on oral, this medicated wine manufacture method is simple, raw material is easy to get, and cost is low, multiple functional, good effect.
Detailed description of the invention
Be clearly and completely described technical scheme of the present invention below, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Compatibility of drugs of the present invention is reasonable, and its compatibility principle is:
Radix Ginseng: property is flat, sweet in the mouth, micro-hardship, tepor.Return spleen, lung meridian, heart channel.Have strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, the effect of Fructus Alpiniae Oxyphyllae of calming the nerves, thinks in Shennong's Herbal, effect that Radix Ginseng has " tonifying five ZANG-organs, peace spirit, determine soul, spasmolytic is throbbed with fear, except pathogen, the happy Fructus Alpiniae Oxyphyllae of improving eyesight ", " take for a long time make light of one's life by commiting suicide prolong life ".The present invention utilizes ginsenoside in Radix Ginseng, ginseng glycopeptide, glycol saponins and ginseng polysaccharide's composition, controls insufficiency of lung-QI, prevent diabetic angiopathy to diabetics, and kidney-reinforcing Yang-strengthening, QI invigorating and blood producing, control diabetics injury of diaphragm.
Fructus Lycii, sweet in the mouth, flat, there is nourishing the liver, nourishing kidney, effect of lung moistening, Fructus Lycii is classified as " medicine-food two-purpose " kind by Ministry of Public Health, and be used to be processed into various food, beverage, health promoting wine, health product etc., the present invention utilizes betanin, aminoacid, polysaccharide component in Fructus Lycii more, to diabetics can invigorating the liver and kidney, benefiting essence-blood, there is improving eyesight, blood sugar lowering, raising cell tissue to effect of the utilization rate of glucose.
Fructus Mume: property is flat, sour in the mouth, puckery, returns liver, spleen, lung, large intestine channel.The present invention utilizes the citric acid in Fructus Mume, malic acid, ceryl alcohol, terpenoid, paddy stays the effective ingredient such as alcohol, the effect of have astringing lung-QI and relieving cough, reducing phlegm, and can control deficiency-heat and quench one's thirst, prevent patient's apoplectic hemiplegia, blood stagnancy due to deficiency of QI, numb limbs and tense tendons to diabetics.
Radix Platycodonis, bitter in the mouth; Pungent; Property flat, return lung meridian, the effect of have lung qi dispersing, eliminating the phlegm, the present invention utilizes the compositions such as the platycodin in Radix Platycodonis, multiple saponin, have diabetics reduce phlegm, promoting the circulation of QI, blood sugar lowering, increase coronary flow, diuresis effect.
Radix Polygalae, bitter in the mouth, pungent, slightly warm in nature, GUIXIN, kidney, lung meridian, main component is saponin, Radix Polygalae alkali, resin, Radix Polygalae ketone etc., and the present invention utilizes the composition such as saponin, Radix Polygalae alkali, resin, Radix Polygalae ketone of Radix Polygalae, the function of carrying out solidifying heart and tranquilizing mind to diabetics, going expectorant to have one's ideas straightened out.
Radix Salviae Miltiorrhizae, sweet in the mouth, warm in nature, nontoxic, enter the heart, spleen, lung three warp, the present invention utilizes TANSHINONES, danshensu, catechol, saivianic acid A (first, second, third) effective ingredient in Radix Salviae Miltiorrhizae, can play antithrombotic, blood fat reducing, the microcirculatory effect of improvement to diabetics blood circulation promoting and blood stasis dispelling, clearing away heart-fire for tranquillization.
Radix Notoginseng, nature and flavor: sweet in the mouth; Micro-hardship; Warm in nature, return Liver Channel; Stomach warp; Heart channel; Lung meridian; Large intestine channel, has hemostasis; Loose blood; Analgesic therapy effect.The present invention utilizes the composition of the saponin in Radix Notoginseng, flavonoid glycoside, performance oil, the sour potassium of Radix Salviae Miltiorrhizae (first, second, third), has hemostasis blood stasis dispelling, blood stasis dispelling, blood sugar lowering, prevent the effect of the retinal vein occlusion to diabetics.
Sanguis Draxonis, sweet in the mouth, sweet, property is put down, GUIXIN, liver, spleen channel, the present invention utilizes the composition such as dracorhodin, dracorubin, flavonol, chalcone, resinic acid in Sanguis Draxonis, can to invigorate blood circulation analgesic therapy, hemostasia and promoting granulation, inhibition thrombosis, promotion plasmin activity to diabetics.
Ganoderma, sweet in the mouth, property is put down, sweet, flat, GUIXIN, liver, spleen, lung, the kidney Five Classics, the present invention utilizes the main component such as triterpenes, organic acid, alkaloid, coumarin glycoside, polysaccharide, ucleosides in Ganoderma, plays tranquilizing by nourishing the heart, benefiting vital QI and blood, blood sugar lowering, blood fat reducing, resists myocardial ischemia, the effect of the kidney invigorating to diabetics.
Rhizoma Sparganii, sweet in the mouth, property is put down, and return spleen, lung, kidney channel, have boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying effect, the present invention utilizes the main component such as performance oil-phenethanol, hydroquinone, hexadecylic acid in Ganoderma, plays removing blood stasis circulation of qi promoting, removing blood stasis to diabetics; 2, antithrombus formation; 3, microcirculation is improved; 4, anti-cerebral ischemia, myocardial ischemia; Deng effect.
Rhizoma Curcumae Longae, acrid in the mouth, hardship, warm in nature.Return spleen, Liver Channel, have effect of removing blood stasis circulation of qi promoting, the present invention utilizes the curcumin in Rhizoma Curcumae Longae, plays wet goods main component, diabetics is played to the effect of removing blood stasis circulation of qi promoting, outer dispersing wind and cold.
Radix Curcumae, acrid in the mouth, hardship, cold in nature, return liver, the heart, lung meridian, the present invention utilizes the main component such as curcumin, curcumene, terpene ethanol, Camphora in Radix Curcumae, plays promoting blood circulation and stopping pain, the effect of promoting QI circulation for relieving depression, blood stasis dispelling to diabetics.
According to the component analysis of above-mentioned component, the open following examples of the present invention.
Embodiment 1:
Get: Radix Ginseng 40 grams; Fructus Lycii 150 grams; Fructus Mume 40 grams; Radix Polygalae 80 grams; Radix Platycodonis 40 grams; Radix Salviae Miltiorrhizae 100 grams; Radix Notoginseng 40 grams; Sanguis Draxonis 150 grams; Ganoderma 50 grams; 40 grams, Rhizoma Curcumae Longae; Radix Curcumae 80 grams, inserts in the pure grain wine 3000 grams of 52 degree by described component, room temperature sealing placement 45 days.
Embodiment 2:
Get: Radix Ginseng 50 grams; Fructus Lycii 200 grams; Fructus Mume 80 grams; Radix Polygalae 100 grams; Radix Platycodonis 80 grams; Radix Salviae Miltiorrhizae 150 grams; Radix Notoginseng 50 grams; Sanguis Draxonis 150 grams; Ganoderma 70 grams; 60 grams, Rhizoma Curcumae Longae; Radix Curcumae 100 grams, inserts in the pure grain wine 6000 grams of 45 degree by described component, room temperature sealing placement 50 days.
Embodiment 3:
Get: Radix Ginseng 100 grams; Fructus Lycii 1200 grams; Fructus Mume 100 grams; Radix Polygalae 150 grams; Radix Platycodonis 100 grams; Radix Salviae Miltiorrhizae 200 grams; Radix Notoginseng 100 grams; Sanguis Draxonis 300 grams; Ganoderma 100 grams; 100 grams, Rhizoma Curcumae Longae; Radix Curcumae 150 grams, inserts in the pure grain wine 5000 grams of 60 degree by described component, room temperature sealing placement 30 days.
In embodiment, described room temperature sealing is relevant to the number of degrees of composition weight and wine for standing time, and the number of degrees of wine are higher, and composition weight is more, then Sealing period suitably can shorten 5-10 days, but lower than 30 days, had better not ensure that the fully molten of drug component is released.
For showing effect of the present invention, the present invention is through clinical observation, and result is as follows:
One, data and method
1, physical data
In more than 300 diabeticss, male accounts for 68%, and women accounts for 32%; 15 ~ 20 years old account for 60%, 40 ~ 59 years old account for more than 21%, 60 years old account for 19%.
2, effect and method is taken
The medicated wine of the oral embodiment of the present invention 1: 20----30 milliliter after cloudy gas wine dinner every day; Within 30 days, be a course for the treatment of, take 3 courses for the treatment of.
3, observational technique
Take period to observe weekly once, comprise symptom, sign improves situation, untoward reaction.
4, result
Diabetics takes 3 courses for the treatment of, and preprandial glucose is by the near 6.4mmcl/L of 9.8mmcl/L, and 2 hours blood glucose values are by the near 8.7mmcl/L of 12.2mmcl/L after the meal.Daytime brightlessness in the daytime; weak; sleepy transference cure, night sleep recovers normal, and the length of one's sleep can reach 6 to 8 hours; the transference cure of numbness of hands and feet, flank pain, from head to foot pruritus; the effect of the molten Chinese medicine of employing wine is the several times of other pharmaceutical methods as can be seen here, and toxic and side effects is little, and blood sugar lowering is lasting; fundamentally can strengthen the complex functionality of cell and the ability of opposing glycolipid toxin, protection islet cells increases B cell quantity.
Through taking of 3 courses for the treatment of, the symptom of diabetics all makes moderate progress, and effective percentage reaches 100%, and improvement situation refers to table
| Sample (people) | Effective (people) | Invalid (people) | Effectively (people) | Effective percentage |
| Man 36 | 1 | 1 | 34 | 94％ |
| Female 30 | 1 | 1 | 28 | 94％ |
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; change can be expected easily or replace, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should described be as the criterion with the protection domain of claim.
Claims (4)
1. to the medicative medicated wine of diabetes tool, it is characterized in that: the wine of 3000 grams ~ 30000 grams has following component:
Radix Ginseng 30 grams ~ 100 grams; Fructus Lycii 100 grams ~ 300 grams; Fructus Mume 30 grams ~ 100 grams; Radix Polygalae 50 grams ~ 150 grams; Radix Platycodonis 30 grams ~ 100 grams; Radix Salviae Miltiorrhizae 50 grams ~ 250 grams; Radix Notoginseng 30 grams ~ 100 grams; Sanguis Draxonis 100 grams ~ 300 grams; Ganoderma 30 grams ~ 100 grams; 30 grams ~ 100 grams, Rhizoma Curcumae Longae; Radix Curcumae 50 grams ~ 150 grams.
2. one according to claim 1 is to the medicative medicated wine of diabetes tool, it is characterized in that: have following component at the wine of 3000 grams ~ 30000 grams: Radix Ginseng 40 grams ~ 80 grams; Fructus Lycii 150 grams ~ 250 grams; Fructus Mume 40 grams ~ 90 grams; Radix Polygalae 80 grams ~ 120 grams; Radix Platycodonis 40 grams ~ 80 grams; Radix Salviae Miltiorrhizae 100 grams ~ 200 grams; Radix Notoginseng 40 grams ~ 80 grams; Sanguis Draxonis 150 grams ~ 250 grams; Ganoderma 50 grams ~ 80 grams; 40 grams ~ 70 grams, Rhizoma Curcumae Longae; Radix Curcumae 80 grams ~ 120 grams.
3. one according to claim 1 is to the medicative medicated wine of diabetes tool, it is characterized in that: have following component at the wine of 3000 grams ~ 30000 grams: Radix Ginseng 50 grams ~ 80 grams; Fructus Lycii 150 grams ~ 200 grams; Fructus Mume 50 grams ~ 80 grams; Radix Polygalae 100 grams ~ 120 grams; Radix Platycodonis 40 grams ~ 50 grams; Radix Salviae Miltiorrhizae 150 grams ~ 200 grams; Radix Notoginseng 40 grams ~ 50 grams; Sanguis Draxonis 150 grams ~ 200 grams; Ganoderma 50 grams ~ 70 grams; 40 grams ~ 70 grams, Rhizoma Curcumae Longae; Radix Curcumae 90 grams ~ 100 grams.
4. one according to claim 1 is to the medicative medicated wine of diabetes tool, it is characterized in that: described wine is the pure grain wine of 40 ~ 60 degree.
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Effective date of registration: 20150914 Address after: 430075, Hubei Wuhan hi tech Zone, East Lake hi tech Zone, 858 High-tech Industrial Park, small and medium-sized enterprise Park Service Center (A-7 building) Patentee after: Niu Zhenghua Address before: 430075, Hubei Wuhan hi tech Zone, East Lake hi tech Zone, 858 High-tech Industrial Park, small and medium-sized enterprise Park Service Center (A-7 building) Patentee before: Wuhan Zhengliyuan Technology Co., Ltd. |