CN103463569A

CN103463569A - Traditional Chinese medicine preparation for treating duodenal ulcer

Info

Publication number: CN103463569A
Application number: CN2013104158039A
Authority: CN
Inventors: 王国明
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-09-06
Filing date: 2013-09-06
Publication date: 2013-12-25

Abstract

The invention discloses a traditional Chinese medicine preparation for treating duodenal ulcer. The traditional Chinese medicine preparation is prepared from lilium brownie, root of red-rooted salvia, folium sennae, rhizoma corydalis, astragalus membranaceus, peach kernel, trogopterus dung, pericarpium citri reticulatae, fiveleaf akebia fruit, dandelion and radix curcumae longae. The traditional Chinese medicine preparation can be clinically used for treating the duodenal ulcer.

Description

A kind of Chinese medicine preparation for the treatment of duodenal ulcer

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine preparation for the treatment of duodenal ulcer.

Background technology

Duodenal ulcer is one of commonly encountered diseases in population of China, frequently-occurring disease.This disease male sickness rate is apparently higher than the women, may be irregular with smoking, life and diet, work and ambient pressure and psychologic factors closely related.In recent years, the sickness rate of duodenal ulcer starts on a declining curve, yet it still belongs to one of modal disease in digestive system disease.The inventor passes through long-term practice and draws, the treatment by Chinese herbs duodenal ulcer has better effect, obtains good effect.

Summary of the invention

The object of the present invention is to provide the Chinese medicine preparation of the treatment duodenal ulcer that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.

The present invention, according to Chinese medical theory, adopts Bulbus Lilii, Radix Salviae Miltiorrhizae, Folium Sennae, Rhizoma Corydalis, the Radix Astragali, Semen Persicae, Oletum Trogopterori, Pericarpium Citri Reticulatae, Fructus Akebiae, Herba Taraxaci, Rhizoma Curcumae Longae, according to certain compatibility requirement, through being processed into.

Preparing Chinese medicine preparation of the present invention is made by following raw material medicaments: Bulbus Lilii 30-50 part, Radix Salviae Miltiorrhizae 30-50 part, Folium Sennae 30-50 part, Rhizoma Corydalis 20-40 part, Radix Astragali 20-40 part, Semen Persicae 10-30 part, Oletum Trogopterori 10-30 part, Pericarpium Citri Reticulatae 10-30 part, Fructus Akebiae 10-30 part, Herba Taraxaci 10-20 part, Rhizoma Curcumae Longae 10-20 part.

Optimum weight part of Chinese medicine preparation crude drug of the present invention is: 40 parts of Bulbus Liliies, 40 parts of Radix Salviae Miltiorrhizaes, 40 parts of Folium Sennae, 30 parts of Rhizoma Corydalis, 30 parts of the Radixs Astragali, 20 parts, Semen Persicae, 20 parts of Oletum Trogopteroris, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Fructus Akebiaes, 15 parts of Herba Taraxacis, 15 parts, Rhizoma Curcumae Longae.

The pharmacological action of Chinese medicine of the present invention is as follows:

Bulbus Lilii: sweet, micro-hardship, be slightly cold, GUIXIN, lung meridian.Nourishing YIN to relieve dryness, clearing away heart-fire for tranquillization.Cure mainly the fidgets due to deficiency palpitation with fear due to unsuccessful of deficiency of YIN chronic cough or feelings will, insomnia and dreamful sleep.

Radix Salviae Miltiorrhizae: bitter, be slightly cold.GUIXIN, Liver Channel.Promoting blood flow to regulate menstruation, the removing heat from blood eliminating carbuncle, calm the nerves.For the ambition of blood stasis, epigastric pain Ji lumps in the chest and abdomen, rheumatic arthralgia, skin infection carbuncle etc.

Folium Sennae: bitter, cold and cool.Return large intestine channel.Purging heat to relax the bowels, consumer product dredge stasis, hemostasis.Constipation with heat retention, habitual constipation, stagnant abdominal distention, edema tympanites, Stomach duodenum ulcerative hemorrhage etc.

Rhizoma Corydalis: acrid, bitter, warm.Return liver, stomach, the heart, lung, spleen channel.Invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving.For all pains of trusted subordinate's waist knee joint, menoxenia, traumatic injury etc.

The Radix Astragali: sweet, warm, return lung, spleen channel.Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.For diarrhea due to hypofunction of the spleen, wait the card of all Qi and blood deficiencies.

Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For multiple blood stasis symptom, dryness of the intestine constipation, lung abscess, acute appendicitis.

Oletum Trogopterori: bitter, salty, sweet, temperature.Return Liver Channel.Promoting blood circulation and stopping pain, removing stasis to stop bleeding.For all cards of stagnation of blood stasis.

Pericarpium Citri Reticulatae: acrid, bitter, warm, return spleen, stomach, lung meridian.In regulating the flow of vital energy and adjusting, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.Full vexed for chest and diaphragm, abdominal distention, anorexia, vomiting etc.

Fructus Akebiae: micro-hardship, property are put down.Return liver, stomach, urinary bladder channel.Dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis.For stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor etc.

Herba Taraxaci: sweet, cold, return liver, stomach warp.Heat-clearing and toxic substances removing, the eliminating carbuncle eliminating stagnation.For carbuncle furuncle, the puckery pain of pyretic stranguria.

Rhizoma Curcumae Longae: bitter in the mouth, suffering, warm in nature.Return spleen, Liver Channel.The removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.The all cards of stagnation of QI and blood, born of the same parents' abdomen hypochondriac pain, dysmenorrhes, the stagnant stomachache of the stasis of blood in puerperal, rheumatic arthralgia, traumatic injury, carbuncle etc.

Chinese medicine preparation of the present invention was in 2008 to 2012 the routine patients of clinical observation duodenal ulcer 100, and clinical report is as follows:

1, physical data

In 100 routine patients, male's 72 examples, women's 28 examples, age 16-67 year, the course of disease is many at 2 months to 5 years, 42.5 years old mean age.

2, diagnostic criteria

2.1 diagnosis basis Ministry of Public Health " guideline of clinical investigations of new Chinese medicine treatment peptic ulcer ":

(1) periodicity of prolonged and repeated outbreak, the chronic epigastrium pain of rhythmicity; (2) epigastrium has limitation deeply in tenderness; (3) the x-ray canel barium meal contrast examination is shown in Ulcer niche; (4) endoscope's microscopy is as seen to active stage ulcer.

2.2 exclusion standard:

(1) plyability ulcer person; (2) person that has the severe complication, as after piercing operation, massive hemorrhage; (3) observer that affects the treatment with Other diseases; (4) anemia of pregnant woman, maybe can not adhere to therapist; (5) postbulbar duodenal ulcer person.

3, Therapeutic Method

3.1 prescription: Bulbus Lilii 40g, Radix Salviae Miltiorrhizae 40g, Folium Sennae 40g, Rhizoma Corydalis 30g, Radix Astragali 30g, Semen Persicae 20g, Oletum Trogopterori 20g, Pericarpium Citri Reticulatae 20g, Fructus Akebiae 20g, Herba Taraxaci 15g, Rhizoma Curcumae Longae 15g.

3.2 method of preparation and use: by said medicine routinely technique make decoction, 1 dose of oral every day, every day 2 times, within 10 days, be a course for the treatment of.

4, therapeutic outcome:

4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":

Clinical cure: cardinal symptom and minor symptom all disappear, and gastroscopy ulcer disappears fully, local mild hyperaemia, but without obvious edema;

Produce effects: primary symptom all has clear improvement with time disease, and gastroscopy ulcer disappears substantially, still has obvious inflammation;

Effectively: primary symptom all has clear improvement with time disease, and the gastroscopy ulcer surface dwindles more than 50%;

Invalid: primary symptom is with time disease all without improving, and the gastroscopy ulcer surface dwindles not as good as 50%.

4.2 result: in 100 routine patients, 58 examples of fully recovering (58%), 35 examples that take a turn for the better (35%), invalid 7 examples (7%), total effective rate is 93%.

5. model case

5.1 Zhu, man, 49 years old.The pain that has a stomach-ache more than 1 year, increase the weight of to accompany melena 5 days.The patient is the outbreak pain that has a stomach-ache repeatedly over one year, and over nearly 5 days, pain increases the weight of, and occurs that stool is shiny black, fatigue and weakness, receive food still can, urine is normal, light red tongue is white, white and thin fur, thready and hesitant pulse.Electronic gastroscopy result: duodenal ulcer.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and gastroscopy ulcer disappears fully, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.

5.2 Xu certain, female, 53 years old.Vague epigastralgia 5 months, previously own the interruption purchased the stomachache medicine and takes, the time during pain only, pain is frequent recently, and when hunger, pain is obvious, after dining, can alleviate, companion's acid regurgitation, belch, Abdeminal pain sense, the time have nauseating, vomit.Electronic gastroscopy result: duodenal ulcer.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and gastralgia, acid regurgitation alleviate, and Abdeminal pain, nauseating, vomiting disappearance, continue to take 3 courses for the treatment of, and symptom and sign disappears, and gastroscopy ulcer disappears fully, after half a year, follows up a case by regular visits to without recurring.

The specific embodiment

Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.

Embodiment 1, and a kind of Chinese medicine preparation for the treatment of duodenal ulcer is made by Bulbus Lilii 30g, Radix Salviae Miltiorrhizae 30g, Folium Sennae 30g, Rhizoma Corydalis 20g, Radix Astragali 20g, Semen Persicae 10g, Oletum Trogopterori 10g, Pericarpium Citri Reticulatae 10g, Fructus Akebiae 10g, Herba Taraxaci 10g, Rhizoma Curcumae Longae 10g.

Embodiment 2, and a kind of Chinese medicine preparation for the treatment of duodenal ulcer is made by Bulbus Lilii 40g, Radix Salviae Miltiorrhizae 40g, Folium Sennae 40g, Rhizoma Corydalis 30g, Radix Astragali 30g, Semen Persicae 20g, Oletum Trogopterori 20g, Pericarpium Citri Reticulatae 20g, Fructus Akebiae 20g, Herba Taraxaci 15g, Rhizoma Curcumae Longae 15g.

Embodiment 3, and a kind of Chinese medicine preparation for the treatment of duodenal ulcer is made by Bulbus Lilii 50g, Radix Salviae Miltiorrhizae 50g, Folium Sennae 50g, Rhizoma Corydalis 40g, Radix Astragali 40g, Semen Persicae 30g, Oletum Trogopterori 30g, Pericarpium Citri Reticulatae 30g, Fructus Akebiae 30g, Herba Taraxaci 20g, Rhizoma Curcumae Longae 20g.

Claims

1. a Chinese medicine preparation for the treatment of duodenal ulcer is characterized in that it is to be made by following raw material medicaments:

Bulbus Lilii 30-50 part, Radix Salviae Miltiorrhizae 30-50 part, Folium Sennae 30-50 part, Rhizoma Corydalis 20-40 part, Radix Astragali 20-40 part, Semen Persicae 10-30 part, Oletum Trogopterori 10-30 part, Pericarpium Citri Reticulatae 10-30 part, Fructus Akebiae 10-30 part, Herba Taraxaci 10-20 part, Rhizoma Curcumae Longae 10-20 part.

2. Chinese medicine preparation according to claim 1 is characterized in that it is to be made by following raw material medicaments:

40 parts of Bulbus Liliies, 40 parts of Radix Salviae Miltiorrhizaes, 40 parts of Folium Sennae, 30 parts of Rhizoma Corydalis, 30 parts of the Radixs Astragali, 20 parts, Semen Persicae, 20 parts of Oletum Trogopteroris, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Fructus Akebiaes, 15 parts of Herba Taraxacis, 15 parts, Rhizoma Curcumae Longae.