CN102824445B - Traditional Chinese medicine composition for treating duodenal ulcer - Google Patents
Traditional Chinese medicine composition for treating duodenal ulcer Download PDFInfo
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- CN102824445B CN102824445B CN 201210350173 CN201210350173A CN102824445B CN 102824445 B CN102824445 B CN 102824445B CN 201210350173 CN201210350173 CN 201210350173 CN 201210350173 A CN201210350173 A CN 201210350173A CN 102824445 B CN102824445 B CN 102824445B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating duodenal ulcer. The traditional Chinese medicine composition is prepared from kalimeris lautureana, ficus variolosa, small algae, folium sennae, rhizoma corydalis, lergefruit hodgsonia, astragalus mongholicus, grifola frondosa, uraria crinita root, dried tangerine or orange peel, fiveleaf akebia fruit and dandelion. The traditional Chinese medicine composition can be clinically used for treating the duodenal ulcer.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of duodenal ulcer.
Background technology
Duodenal ulcer is commonly encountered diseases, frequently-occurring disease clinically, having outbreak tendency repeatedly.Treated duodenal ulcer single western medicine therapy commonly used in the past, doctor trained in Western medicine takes antiulcer and anti helicobacter pylori medicine with using, or behind ulcer healing, adopt low dose of bisfentidine to keep treatment and reduce relapse rate, but take unavoidable side effect for a long time, but effect is not satisfactory, long-term practice through the inventor draws, and Chinese medicine is controlled duodenal ulcer and had better effect, obtains good effect.
Summary of the invention
The Chinese medicine composition of the treatment duodenal ulcer that the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt mountain Herba Kalimeridis, Ficus Variolosa Lindl. Ex Benth., Gigartina intermedia Sur., Folium Sennae, Rhizoma Corydalis, Hodgsonia macrocarpa, the Radix Astragali, Grifola frondosa, Herba Urariae crinitae, Pericarpium Citri Reticulatae, Fructus Akebiae, Herba Taraxaci according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention and make mountain Herba Kalimeridis 40-70 part, Ficus Variolosa Lindl. Ex Benth. 30-50 part, Gigartina intermedia Sur. 30-50 part, Folium Sennae 30-50 part, Rhizoma Corydalis 20-40 part, Hodgsonia macrocarpa 20-40 part, Radix Astragali 20-40 part, Grifola frondosa 10-30 part, Herba Urariae crinitae 10-30 part, Pericarpium Citri Reticulatae 10-30 part, Fructus Akebiae 10-30 part, Herba Taraxaci 10-20 part by following raw material medicaments.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 60 parts of mountain Herba Kalimeridis, 40 parts of Ficus Variolosa Lindl. Ex Benth., 40 parts of Gigartina intermedia Sur., 40 parts of Folium Sennae, 30 parts of Rhizoma Corydalis, 30 parts of Hodgsonia macrocarpa, 30 parts of the Radixs Astragali, 20 parts of Grifola frondosa, 20 parts of Herba Urariae crinitae, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Fructus Akebiaes, 15 parts of Herba Taraxacis.
The pharmacological action of Chinese medicine of the present invention is as follows:
Mountain Herba Kalimeridis: bitter, cold.Heat-clearing and toxic substances removing, hemostasis.Be used for cold, fever, cough, acute pharyngitis, tonsillitis, infectious hepatitis, stomach, duodenal ulcer, furuncle toxic swelling, mastitis, diseases such as traumatic hemorrhage.
Ficus Variolosa Lindl. Ex Benth.: little hardship, suffering, tepor.Expelling wind and removing dampness, promoting blood circulation and stopping pain, lactogenic.Be used for rheumatic arthralgia, stomachache, furuncle and phyma, traumatic injury, agalactia, diseases such as duodenal ulcer.
Gigartina intermedia Sur.: sweet, salty, cold.Return stomach, large intestine channel.Heat clearing away, stomach function regulating, relieving constipation.Be used for gastric and duodenal ulcers, chronic constipation etc.
Folium Sennae: bitter, cold and cool.Return large intestine channel.Purging heat to relax the bowels, consumer product dredge stasis, hemostasis.Constipation with heat retention, habitual constipation, stagnant abdominal distention, edema tympanites, stomach, duodenal ulcer and hemorrhage etc.
Rhizoma Corydalis: hot, bitter, warm.Return liver, stomach, the heart, lung, spleen channel.Invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving.Be used for all pains of trusted subordinate's waist knee joint, menoxenia, traumatic injury etc.
Hodgsonia macrocarpa: sweet, cool.Return the stomach warp.Cooling blood for hemostasis, heat-clearing and toxic substances removing.Be used for stomach, duodenal ulcer and hemorrhage, traumatic hemorrhage, furuncle swells and ache, eczema etc.
The Radix Astragali: sweet, warm, return lung, spleen channel.Benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.Be used for diarrhea due to hypofunction of the spleen, wait the card of all Qi and blood deficiencies.
Grifola frondosa: sweet, flat.Replenishing QI to invigorate the spleen, tonify deficiency are set upright.Be used for deficiency of the spleen causing weakness of QI, fatigue and asthenia, spiritlessness and sparing of words; Diet reduces, abdominal distention after meal; The person that has the above-mentioned symptom after tumor patient radiotherapy or the chemotherapy.
Herba Urariae crinitae: sweet, little hardship, flat.GUIXIN, lung, Liver Channel.Clearing away lung-heat to relieve cough, the dissipating blood stasis hemostasis.Be used for the cough due to lung-heat, lung abscess is gathered, acute mastitis, and proctoptosis, hematuria, traumatic hemorrhage etc. are spitted blood in uterine prolapse.
Pericarpium Citri Reticulatae: hot, bitter, warm, return spleen, stomach, lung meridian.Regulate the flow of vital energy and transfer, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.It is full vexed to be used for chest and diaphragm, abdominal distention, anorexia, vomiting etc.
Fructus Akebiae: little hardship, property are put down.Return liver, stomach, urinary bladder channel.Dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis.Be used for stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor etc.
Herba Taraxaci: sweet, cold, return liver, stomach warp.Heat-clearing and toxic substances removing, the eliminating carbuncle eliminating stagnation.Be used for carbuncle furuncle, the puckery pain of pyretic stranguria.
Duodenal ulcer belongs to the traditional Chinese medical science " gastric abscess " category more.Clinically see with deficiency syndrome or simulataneous insufficiency and excessive more.The cause of disease mostly is eating and drinking without temperance, disorder of emotion, overstrain internal injury equivalent damage taste, causes weakness of the spleen and stomach, dysfunction of the spleen in transportation and transformation, or folder is wet, folder heat, or prolonged illness causes the stasis of blood, so methods such as soothing liver and strengthening spleen, regulating QI to relieve pain, blood stasis dispelling removing dampness, heat clearing away are the method for primary disease treatment.The mountain Herba Kalimeridis has the effect of heat-clearing and toxic substances removing, hemostasis among the present invention, be monarch drug, Ficus Variolosa Lindl. Ex Benth., Gigartina intermedia Sur., Folium Sennae expelling wind and removing dampness, promoting blood circulation and stopping pain, stomach function regulating relieving constipation, be ministerial drug, Rhizoma Corydalis, the hemostasis of Herba Urariae crinitae dissipating blood stasis, Hodgsonia macrocarpa, Herba Taraxaci clearing away heat to stop bleeding, the Radix Astragali, Grifola frondosa replenishing QI to invigorate the spleen, Pericarpium Citri Reticulatae, Fructus Akebiae depressed liver-energy dispersing and QI regulating, and stomach and alleviating pain.Find that through clinical practice duodenal ulcer is had unique curative effect, all medicines are played the effect of heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, invigorating the spleen and benefiting QI altogether, reach the purpose for the treatment of duodenal ulcer.
Chinese medicine composition of the present invention was in 2009 to 2011 clinical observation duodenal ulcer 120 routine patients, and clinical report is as follows:
1, physical data
Among the 120 routine patients, age 18-65 year, the course of disease is many at 3 months to 8 years, 45 years old mean age.
2, diagnostic criteria
2.1 diagnosis basis Ministry of Public Health " the clinical research guideline of new Chinese medicine treatment peptic ulcer ":
(1) periodicity of prolonged and repeated outbreak, the chronic epigastrium pain of rhythmicity; (2) epigastrium has limitation deeply in tenderness; (3) X line canel barium meal contrast examination is seen the ulcer niche; (4) endoscope's microscopy can be seen active stage ulcer.
2.2 exclusion standard:
(1) plyability ulcer person; (2) person that has the severe complication, as behind the piercing operation, massive hemorrhage; (3) observer that affects the treatment with other disease; (4) anemia of pregnant woman maybe can not adhere to therapist; (5) postbulbar duodenal ulcer person.
3, Therapeutic Method
3.1 prescription: mountain Herba Kalimeridis 60g, Ficus Variolosa Lindl. Ex Benth. 40g, Gigartina intermedia Sur. 40g, Folium Sennae 40g, Rhizoma Corydalis 30g, Hodgsonia macrocarpa 30g, Radix Astragali 30g, Grifola frondosa 20g, Herba Urariae crinitae 20g, Pericarpium Citri Reticulatae 20g, Fructus Akebiae 20g, Herba Taraxaci 15g.
3.2 preparation and using method: said medicine technology is routinely made decoction, and 1 dose of every day, every day 2 times, 15 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Clinical cure: cardinal symptom and minor symptom all disappear, the complete obiteration of gastroscopy ulcer, and local mild hyperaemia, but do not have obvious edema;
Produce effects: primary symptom all has clear improvement with time disease, and gastroscopy ulcer disappears substantially, still has obvious inflammation;
Effectively: primary symptom all has clear improvement with time disease, and the gastroscopy ulcer surface dwindles more than 50%;
Invalid: primary symptom does not all have improvement with time disease, and the gastroscopy ulcer surface dwindles not as good as 50%.
4.2 result: among the 120 routine patients, 68 examples of fully recovering (56.7%), 46 examples that take a turn for the better (38.3%), invalid 6 examples (5%), total effective rate is 95%.
Model case
1, grandson, woman, 45 years old.Gastric abscess shows effect repeatedly over 3 years, scorching hot pain, and acid regurgitation increases the weight of when hungry, must eat alleviation, and though scorching being difficult to resolve of defecating is remission behind western medicine repeatly, recurrence again soon.Increased the weight of red tongue, white and thin fur, stringy and rolling pulse, electronic gastroscopy result: duodenal ulcer (active stage) in nearly 2 days.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and conscious gastral cavilty is comfortable, and appetite takes a turn for the better, and continues to take 2 courses for the treatment of, the complete obiteration of gastroscopy ulcer, and recovery from illness is followed up a case by regular visits to after 1 year and is not had recurrence.
2, Liu, man, 38 years old.Gastralgia 2 years is surplus, increases the weight of to accompany melena 3 days.Patient's gastralgia of showing effect repeatedly over 2 years, when hungry and hypnalgia very, pain increases the weight of over nearly 3 days, and it is shiny black stool to occur, fatigue and weakness, receive food still can, urine is normal, light red tongue is white, white and thin fur, thready and hesitant pulse.Electronic gastroscopy result: duodenal ulcer.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, the complete obiteration of gastroscopy ulcer, and recovery from illness is followed up a case by regular visits to after 1 year and is not had recurrence.
3, Liu, man, 51 years old.Vague epigastralgia half a year, previously own the interruption purchased the stomachache medicine and takes, and time ends when painful, and pain is frequent recently, and pain is obvious when hunger, can alleviate after the dining, companion's acid regurgitation, belch, upper abdomen feeling of repletion, the time have nauseating, vomit.Electronic gastroscopy result: duodenal ulcer.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and gastralgia, acid regurgitation alleviate, and upper abdomen is glutted, nauseating, vomiting disappears, and continues to take 3 courses for the treatment of, and symptom and sign disappears, and the complete obiteration of gastroscopy ulcer is followed up a case by regular visits to after 1 year and do not had recurrence.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and following this embodiment only for explanation the present invention to the present invention without limits.
Embodiment 1, a kind of Chinese medicine composition for the treatment of duodenal ulcer is to be made by mountain Herba Kalimeridis 40g, Ficus Variolosa Lindl. Ex Benth. 30g, Gigartina intermedia Sur. 30g, Folium Sennae 30g, Rhizoma Corydalis 20g, Hodgsonia macrocarpa 20g, Radix Astragali 20g, Grifola frondosa 10g, Herba Urariae crinitae 10g, Pericarpium Citri Reticulatae 10g, Fructus Akebiae 10g, Herba Taraxaci 10g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of duodenal ulcer is to be made by mountain Herba Kalimeridis 60g, Ficus Variolosa Lindl. Ex Benth. 40g, Gigartina intermedia Sur. 40g, Folium Sennae 40g, Rhizoma Corydalis 30g, Hodgsonia macrocarpa 30g, Radix Astragali 30g, Grifola frondosa 20g, Herba Urariae crinitae 20g, Pericarpium Citri Reticulatae 20g, Fructus Akebiae 20g, Herba Taraxaci 15g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of duodenal ulcer is to be made by mountain Herba Kalimeridis 70g, Ficus Variolosa Lindl. Ex Benth. 50g, Gigartina intermedia Sur. 50g, Folium Sennae 50g, Rhizoma Corydalis 40g, Hodgsonia macrocarpa 40g, Radix Astragali 40g, Grifola frondosa 30g, Herba Urariae crinitae 30g, Pericarpium Citri Reticulatae 30g, Fructus Akebiae 30g, Herba Taraxaci 20g.
Claims (2)
1. a Chinese medicine composition for the treatment of duodenal ulcer is characterized in that it is to be made by following raw material medicaments: mountain Herba Kalimeridis 40-70 part, Ficus Variolosa Lindl. Ex Benth. 30-50 part, Gigartina intermedia Sur. 30-50 part, Folium Sennae 30-50 part, Rhizoma Corydalis 20-40 part, Hodgsonia macrocarpa 20-40 part, Radix Astragali 20-40 part, Grifola frondosa 10-30 part, Herba Urariae crinitae 10-30 part, Pericarpium Citri Reticulatae 10-30 part, Fructus Akebiae 10-30 part, Herba Taraxaci 10-20 part.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by following raw material medicaments: 60 parts of mountain Herba Kalimeridis, 40 parts of Ficus Variolosa Lindl. Ex Benth., 40 parts of Gigartina intermedia Sur., 40 parts of Folium Sennae, 30 parts of Rhizoma Corydalis, 30 parts of Hodgsonia macrocarpa, 30 parts of the Radixs Astragali, 20 parts of Grifola frondosa, 20 parts of Herba Urariae crinitae, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Fructus Akebiaes, 15 parts of Herba Taraxacis.
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| CN103961632A (en) * | 2014-05-29 | 2014-08-06 | 蚌埠明日欣医药有限公司 | Traditional Chinese medicinal composition for treating gastric ulcer and duodenal ulcer |
| CN104606391A (en) * | 2015-01-15 | 2015-05-13 | 陈吉美 | Traditional Chinese medicine composition for treating duodenal ulcers |
| CN104857130A (en) * | 2015-06-02 | 2015-08-26 | 王丽红 | Traditional Chinese medicine for treating deficiency-cold type duodenal ulcer |
| CN104958670A (en) * | 2015-07-16 | 2015-10-07 | 张桂玲 | Traditional Chinese medicine for treating qi-collapse type duodenal ulcer |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100651A (en) * | 1994-03-15 | 1995-03-29 | 广东医学院医药科技开发中心 | Chinese herbal prepn. for curing chronic gastroenteritis and peptic gastric ulcer |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100651A (en) * | 1994-03-15 | 1995-03-29 | 广东医学院医药科技开发中心 | Chinese herbal prepn. for curing chronic gastroenteritis and peptic gastric ulcer |
Non-Patent Citations (2)
| Title |
|---|
| 张媛媛，曾令西.中西医结合治疗难治性消化性溃疡30例.《四川中医》.2007,第25卷(第12期),64－65. * |
| 段国勋,王瑛.中医药治疗消化性溃疡病的近况.《泸州医学院学报》.1990,第13卷(第2期),156-158. * |
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