CN103463500A - Medicament for treating cerebral hemorrhage - Google Patents
Medicament for treating cerebral hemorrhage Download PDFInfo
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Abstract
The invention discloses a medicament for treating cerebral hemorrhage, and belongs to the field of traditional Chinese medicines. The effective components of the medicament comprise raw materials: winter melon vine, laportea macrostachya, hypericum sampsonii, ficus pumila, peganum harmala, craibiodendron yunnanense, wikstroemia canescens, sargent craneberrybuch branchlet, lemongrass, cortex daphnes, ventilago leiocarpa benth, hylomecon japonica, mulberry roots, sarcandra glabra, clerodendrum thomsonae and prinos-like salacia root. The medicament of the invention has efficacies of supplementing the center, boosting qi, softening blood vessels, freeing the channels, activating collaterals, enlivening spirit and opening the orifices, has substantial treatment effect on cerebral hemorrhage, and is fast in effectiveness and none in toxic and side effects; the medicament is verified by clinics that the medicament has good treatment effect on cerebral hemorrhage and sequelaes caused thereby; and the medicament has the advantages of easily available medicinal material, low cost, high cure rate, no sequelae, safety and reliability, and is worth widely popularizing and applying.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine for the treatment of cerebral hemorrhage.
Background technology
Cerebral hemorrhage refers to hemorrhage that in non-traumatic cerebral essence, angiorrhexis causes, the modal cause of disease is hypertension, cerebral arteriosclerosis, intracranial vascular malformation etc., normal bring out because of the factor such as exert oneself, excited, therefore sudden onset aprowl mostly, the cerebral hemorrhage morbidity is very rapid clinically, and main manifestations is the neural infringements such as disturbance of consciousness, hemiplegia of limb, aphasia; The cerebral hemorrhage onset is hurried, the state of an illness is dangerous, mortality rate is very high, the most serious a kind of in acute cerebrovascular disease, for current middle-aged and elderly people fatal disease it-, because it is dead and disability rate is high, so national governments and hygiene department are to all very attention of its preventing and controlling.Epidemiological study shows, the prevalence of cerebrovascular is 500-700,/10 ten thousand population, statistics are basically identical both at home and abroad, China's urban is up to 10,00/,100,000 populations, annual sickness rate is 165-245,/10 ten thousand population, statistics according to 57 countries of cerebrovascular cooperative groups of World Health Organization (WHO), cerebrovascular is classified 40 countries that have of front 3 kinds of causes of death as, the patient who dies of illness because of cerebrovascular accounts for 11.3% of 57 national general mortality rate, and majority state mortality of cerebrovascular disease rate approached for 1,00/,100,000 population years.China is one of district occurred frequently of cerebrovascular in world wide, and cerebrovascular is the deputy cause of death of resident nearly ten years always, is only second to malignant tumor, and some cities, the north have risen to first.The case fatality rate of cerebral hemorrhage is 40-60%, account for the major part in the mortality of cerebrovascular disease number, all right both at home and abroad: in the survivor 70-80% leave invalid, and 40% left and right is attached most importance to residual, to the patient, cause huge life to threaten, quality of life is had a strong impact on simultaneously, causes white elephant also to patient family and even entire society.
The western medicine cerebral hemorrhage, multiplex in acute stages treated, the shortcoming of Western medicine is that action target spot is single, therefore clinical effectiveness can not be fully up to expectations, so, for the apoplexy sequela patient, only have treatment by Chinese herbs, can reach efficacy enhancing and toxicity reducing, the therapeutic effect for the treatment of both the principal and secondary aspects of a disease, but existing treatment by Chinese herbs is long the course for the treatment of, easily recurrence, so clinical in the urgent need to a kind of for the complicated pathogenesis of cerebral hemorrhage, determined curative effect, convenient and safe, stay-in-grade first aid using medicine.
Summary of the invention
The invention provides a kind of medicine for the treatment of cerebral hemorrhage, effect with invigorating the spleen and replenishing QI, vessel softening, dredge the meridian passage, consciousness and resuscitation restoring, evident in efficacy to the treatment cerebral hemorrhage, instant effect, have no side effect, through clinical verification, the sequela for the treatment of cerebral hemorrhage and cause is had to good therapeutic effect; Medicine medicinal raw material of the present invention is easy to get, and with low cost, cure rate is high, does not stay sequela and safe and reliable, and application should be widely promoted.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of medicine for the treatment of cerebral hemorrhage, raw material composition and the parts by weight of making described effective ingredient are:
49～74 parts of 53～79 parts of Caulis fici pumilae (Fructus Fici Pumilae)s of 54～79 portions of Herba Hyperici Sampsoniis of 59～84 parts of Radix Laporteae Macrostachyaes of Caulis Benincasae
39～60 parts of 41～64 parts of Folium et Cacumen Viburni Sargentii of 44～69 parts of Flos Wikstroemiae Dolichanthaes of 45～72 parts of Folium Craibiodendri Yunnanensiss of Herba pegani harmalae
7 34～47 parts of 34～54 portions of Semen Hoveniae (Fructus Hoveniae)s of 36～55 parts of Radix Cudraniaes of 39～59 parts of Daphne giraldii Nitsche of Herba Cymbopogonis Citrari
10～29 parts of 19～39 portions of Radix salaciae prinoidiss of 26～42 parts of Herba Anagallidis Arvensiss of 29～44 parts of Herba Sarcandraes of Radix Mori.
Raw material composition and the parts by weight of making described effective ingredient are:
54～66 parts of 55～74 parts of Caulis fici pumilae (Fructus Fici Pumilae)s of 59～75 portions of Herba Hyperici Sampsoniis of 64～79 parts of Radix Laporteae Macrostachyaes of Caulis Benincasae
43～57 parts of 44～62 parts of Folium et Cacumen Viburni Sargentii of 47～64 parts of Flos Wikstroemiae Dolichanthaes of 49～69 parts of Folium Craibiodendri Yunnanensiss of Herba pegani harmalae
7 35～44 parts of 37～49 portions of Semen Hoveniae (Fructus Hoveniae)s of 39～52 parts of Radix Cudraniaes of 42～54 parts of Daphne giraldii Nitsche of Herba Cymbopogonis Citrari
14～24 parts of 22～29 portions of Radix salaciae prinoidiss of 29～39 parts of Herba Anagallidis Arvensiss of 32～41 parts of Herba Sarcandraes of Radix Mori.
Raw material composition and the parts by weight of making described effective ingredient are:
57～65 parts of 59～69 parts of Caulis fici pumilae (Fructus Fici Pumilae)s of 64～70 portions of Herba Hyperici Sampsoniis of 69～74 parts of Radix Laporteae Macrostachyaes of Caulis Benincasae
47～54 parts of 49～59 parts of Folium et Cacumen Viburni Sargentii of 51～59 parts of Flos Wikstroemiae Dolichanthaes of 54～64 parts of Folium Craibiodendri Yunnanensiss of Herba pegani harmalae
7 38～41 parts of 39～44 portions of Semen Hoveniae (Fructus Hoveniae)s of 42～48 parts of Radix Cudraniaes of 44～49 parts of Daphne giraldii Nitsche of Herba Cymbopogonis Citrari
17～19 parts of 24～26 portions of Radix salaciae prinoidiss of 32～34 parts of Herba Anagallidis Arvensiss of 34～39 parts of Herba Sarcandraes of Radix Mori.
Raw material composition and the parts by weight of making described effective ingredient are:
62 parts of 64 parts of Caulis fici pumilae (Fructus Fici Pumilae)s of 67 portions of Herba Hyperici Sampsoniis of 72 parts of Radix Laporteae Macrostachyaes of Caulis Benincasae
50 parts of 54 parts of Folium et Cacumen Viburni Sargentii of 55 parts of Flos Wikstroemiae Dolichanthaes of 59 parts of Folium Craibiodendri Yunnanensiss of Herba pegani harmalae
7 39 parts of 42 portions of Semen Hoveniae (Fructus Hoveniae)s of 45 parts of Radix Cudraniaes of 47 parts of Daphne giraldii Nitsche of Herba Cymbopogonis Citrari
18 parts of 25 portions of Radix salaciae prinoidiss of 33 parts of Herba Anagallidis Arvensiss of 37 parts of Herba Sarcandraes of Radix Mori.
A kind of preparation method for the treatment of the medicine of cerebral hemorrhage comprises following processing step:
(1) Herba Hyperici Sampsonii, Herba pegani harmalae, Flos Wikstroemiae Dolichanthae, Herba Cymbopogonis Citrari, Daphne giraldii Nitsche, Radix Cudraniae, Radix Mori and Herba Sarcandrae are cleaned, put into container, add the distilled water of 8～10 times of amounts, after soaking 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that 60 ℃ of lower relative densities are 1.10～1.13, standby;
(2) Folium Craibiodendri Yunnanensis and Folium et Cacumen Viburni Sargentii are mixed, carried out pulverization process after mix homogeneously, ground into powder, crossed 160 order fine powders, standby;
(3) Caulis Benincasae, Caulis fici pumilae (Fructus Fici Pumilae) and Herba Anagallidis Arvensis are cleaned, chopping, put into container, strand juice, and filter impurity, stay juice standby;
(4) Radix Laporteae Macrostachyae, Semen Hoveniae (Fructus Hoveniae) seven and Radix salaciae prinoidis are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaim ethanol, filter, and the thick paste that 65 ℃ of lower relative densities of simmer down to are 1.12～1.18, standby;
(5) above-mentioned steps (1)～(4) prepared thick paste, fine powder and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make tablet, obtain the medicine for the treatment of cerebral hemorrhage of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Caulis Benincasae: bitter in the mouth, cold in nature; Return lung, Liver Channel.Removing heat from the lung and dissipating phlegm, dredge the meridian passage.Main lung-heat expectoration, articular instability, proctoptosis, skin ulcer scabies." book on Chinese herbal medicine is new again " carries: " dry and chase after wind in active stimulating the menstrual flow, sharp joint, and vim and vigour.”
Radix Laporteae Macrostachyae: hot, bitter, cold, slightly poisonous.Wind-damp dispelling, the meridian dredging, removing toxic substances and promoting subsidence of swelling.Cure mainly lumbago and skelalgia, apathy, migratory arthralgia edema, tuberculous lymphadenitis, venom.
Herba Hyperici Sampsonii: hardship, suffering, cold; Return liver, spleen channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing, promoting blood flow to regulate menstruation, dispelling wind and removing obstruction in the collateral.Main haematemesis, spitting of blood, epistaxis, stranguria with blood, menoxenia, dysmenorrhea, leucorrhea, traumatic injury, rheumatic arthralgia, lumbago and skelalgia, external also can be controlled tinea capitis, aphtha, corneal nebula.Carry " vegetation is side just ": " hemostasis, analgesic therapy, convenient, to stimulate the menstrual flow, stimulating milk secretion, expedite the emergence of.”
Caulis fici pumilae (Fructus Fici Pumilae): sour in the mouth, cool in nature.Expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances and promoting subsidence of swelling.The main air pain of dampness syndrome, sciatica, dysentery, urine drenches, edema, malaria, amenorrhea, postnatal blood stasis stomachache, laryngopharynx swelling and pain, orchitis, dermatitis rhus, pain pyogenic infections from tumour or sore, traumatic injury." Chinese herbal medicine is commonly used in Shanghai " carries: " wind-damp dispelling, dredge the meridian passage, clearing heat for detumescence, diuresis, hemostasis.The dispelling the wind and dampness pathogens pain, brothers' articular instability.”
Herba pegani harmalae: sour, sweet, flat, poisonous.The lung qi dispersing cough-relieving, wind-damp dispelling, removing toxic substances; Cough and asthma; Innominate toxic swelling is controlled in external, rheumatic arthritis." the sweet peaceful blue or green Chinese herbal medicine choosing in Shan " carries: " lung qi dispersing cough-relieving, dredge the meridian passage, removing toxic substances dehumidifying.Control tracheitis, rheumatic arthritis, palpitation and short breath, headache, dizziness "
Folium Craibiodendri Yunnanensis: hot, puckery, temperature, poisonous.Eliminating stasis to stop pain, expelling wind and removing dampness, stop blooding sensible.For traumatic injury, traumatic stupor, bruise, lumbago and skelalgia, hemiplegia, paralysis, rheumatic arthritis, traumatic hemorrhage, fracture." Yunnan Chinese herbal medicine " carries: " relieving superficies and warmign meridians, activating collaterals to relieve pain.Control traumatic injury, rheumatic numbness, affection of exogenous wind-cold.”
Flos Wikstroemiae Dolichanthae: acrid in the mouth, hardship, cold in nature, poisonous; Return the stomach warp.Removing fluid-retention by purgation, hard removing mass disappears.Main phlegm retention, cough with dyspnea, edema, generalized edema with distention of the chest and abdomen in larynx, lump in the abdomen mass beside the umbilicus." herbal classic " carries: " removing mass is poly-, large hard lump in the abdomen, cleanses in the intestines and stomach and stays addiction, diet, cold and heat pathogen, dredging water passages for main typhoid fever pyrexial malaria, lower 12 water.”
Folium et Cacumen Viburni Sargentii: sweet in the mouth, hardship, property is flat.Dredge the meridian passage, detoxifying and relieving itching.Main lumbago and skelalgia, lumbar sprain and QI divergeny, furuncle, scabies, skin pruritus." Jilin Chinese herbal medicine " carries: " dredge the meridian passage, hemostasis, analgesia, cough-relieving.Control pain in the low back and legs, traumatic injury.”
Herba Cymbopogonis Citrari: suffering, temperature, sweet.Dispelling wind and removing obstruction in the collateral, warming middle-JIAO to relieve pain, antidiarrheal, main flu head-body-pain, anemofrigid-damp arthralgia, coldness and pain in the epigastrium, have loose bowels, traumatic injury.Carry in " south of the Five Ridges gather medicinal herbs record ": " loose traumatic injury is hindered blood stasis, the meridian dredging.The wind syndrome of head pain, decoct washing with it.By the same stir-fry of Herba Cymbopogonis Citrari and rice, add the decocting drink, sealing rushes down.Decoct the washing body, the detumescence of can dispeling the wind, separate stench.Extract its oil, can only suffer from abdominal pain.”
Daphne giraldii Nitsche: bitter, hot, temperature, slightly poisonous.Dispelling wind and removing obstruction in the collateral, stasis-dispelling and pain-killing, for headache, toothache, rheumatic arthritis, traumatic injury, stomachache, pain in the hepatic region." Shaanxi Chinese herbal medicine " carries: " cure cold, rheumatalgia, apoplexy numbness, hemiplegia, itchy skin eruption.”
Radix Cudraniae: micro-hardship, flat.Relieving cough and resolving phlegm, expelling wind and removing dampness, eliminating stasis to stop pain.For pulmonary tuberculosis, icterohepatitis, hepatosplenomegaly, Stomach duodenum ulcer, rheumatic lumbago and scelalgia; Fracture is controlled in external, traumatic injury." Nanning City's medicine will " carries: " blood stimulates the menstrual flow, and controls stranguria with turbid discharge, goes long-pending, the calculus of the many years ago stasis of blood.”
Semen Hoveniae (Fructus Hoveniae) seven: hardship, flat.Dispelling wind and removing obstruction in the collateral, dissipating blood stasis for subsidence of swelling.The main air pain of dampness syndrome, traumatic injury.
Radix Mori: micro-hardship, cold in nature; Return Liver Channel.The heat clearing away arresting convulsion, dispelling wind and removing obstruction in the collateral; Main infantile convulsion, conjunctival congestion, toothache, bones and muscles pain." Nanjing medicinal herbs among the people " carry: " control bones and muscles pain, hypertension.”
Herba Sarcandrae: bitter, hot, flat; GUIXIN, Liver Channel.Clearing away heat and cooling blood, the speckle removing of invigorating blood circulation, dispelling wind and removing obstruction in the collateral.For heat in blood purpura, purpura, rheumatic arthralgia, traumatic injury.
Herba Anagallidis Arvensis: sour-puckery flavor is nontoxic.Control all poisonous snakes or lyssodexis, strand juice is for oral administration, and slag applies affected part, controls again cloudy disease skin infection and the arthroncus of knee.
Radix salaciae prinoidis: puckery, temperature; Return liver, kidney channel.Dispelling wind and removing obstruction in the collateral, restore menstrual flow and invigorate blood circulation.Main air arthralgia chiefly caused by damp pathogen card, blood pain lumbago.
The present invention compared with prior art, has following beneficial effect:
Medicine of the present invention has the effect of invigorating the spleen and replenishing QI, vessel softening, dredge the meridian passage, consciousness and resuscitation restoring, and evident in efficacy to the treatment cerebral hemorrhage, instant effect, have no side effect, and through clinical verification, the sequela for the treatment of cerebral hemorrhage and cause is had to good therapeutic effect; Medicine medicinal raw material of the present invention is easy to get, and with low cost, cure rate is high, does not stay sequela and safe and reliable, and application should be widely promoted.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
Caulis Benincasae 79g Radix Laporteae Macrostachyae 75g Herba Hyperici Sampsonii 74g Caulis fici pumilae (Fructus Fici Pumilae) 66g
Herba pegani harmalae 69g Folium Craibiodendri Yunnanensis 64g Flos Wikstroemiae Dolichanthae 62g Folium et Cacumen Viburni Sargentii 57g
Herba Cymbopogonis Citrari 54g Daphne giraldii Nitsche 52g Radix Cudraniae 49g Semen Hoveniae (Fructus Hoveniae) seven 44g
Radix Mori 41g Herba Sarcandrae 39g Herba Anagallidis Arvensis 29g Radix salaciae prinoidis 24g.
A kind of preparation method for the treatment of the medicine of cerebral hemorrhage comprises following processing step:
(1) Herba Hyperici Sampsonii, Herba pegani harmalae, Flos Wikstroemiae Dolichanthae, Herba Cymbopogonis Citrari, Daphne giraldii Nitsche, Radix Cudraniae, Radix Mori and Herba Sarcandrae are cleaned, put into container, add the distilled water of 8～10 times of amounts, after soaking 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that 60 ℃ of lower relative densities are 1.10～1.13, standby;
(2) Folium Craibiodendri Yunnanensis and Folium et Cacumen Viburni Sargentii are mixed, carried out pulverization process after mix homogeneously, ground into powder, crossed 160 order fine powders, standby;
(3) Caulis Benincasae, Caulis fici pumilae (Fructus Fici Pumilae) and Herba Anagallidis Arvensis are cleaned, chopping, put into container, strand juice, and filter impurity, stay juice standby;
(4) Radix Laporteae Macrostachyae, Semen Hoveniae (Fructus Hoveniae) seven and Radix salaciae prinoidis are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaim ethanol, filter, and the thick paste that 65 ℃ of lower relative densities of simmer down to are 1.12～1.18, standby;
(5) above-mentioned steps (1)～(4) prepared thick paste, fine powder and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make tablet, obtain the medicine for the treatment of cerebral hemorrhage of the present invention.
Usage and dosage: oral, every day 2 times, each 2 (every 0.5g), warm water delivery services after meal; Within 9 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2～3 courses for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Caulis Benincasae 74g Radix Laporteae Macrostachyae 70g Herba Hyperici Sampsonii 69g Caulis fici pumilae (Fructus Fici Pumilae) 65g
Herba pegani harmalae 64g Folium Craibiodendri Yunnanensis 59g Flos Wikstroemiae Dolichanthae 59g Folium et Cacumen Viburni Sargentii 54g
Herba Cymbopogonis Citrari 49g Daphne giraldii Nitsche 48g Radix Cudraniae 44g Semen Hoveniae (Fructus Hoveniae) seven 41g
Radix Mori 39g Herba Sarcandrae 34g Herba Anagallidis Arvensis 26g Radix salaciae prinoidis 19g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
Caulis Benincasae 72g Radix Laporteae Macrostachyae 67g Herba Hyperici Sampsonii 64g Caulis fici pumilae (Fructus Fici Pumilae) 62g
Herba pegani harmalae 59g Folium Craibiodendri Yunnanensis 55g Flos Wikstroemiae Dolichanthae 54g Folium et Cacumen Viburni Sargentii 50g
Herba Cymbopogonis Citrari 47g Daphne giraldii Nitsche 45g Radix Cudraniae 42g Semen Hoveniae (Fructus Hoveniae) seven 39g
Radix Mori 37g Herba Sarcandrae 33g Herba Anagallidis Arvensis 25g Radix salaciae prinoidis 18g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of effective ingredient of the present invention forms and weight is:
Caulis Benincasae 69g Radix Laporteae Macrostachyae 64g Herba Hyperici Sampsonii 59g Caulis fici pumilae (Fructus Fici Pumilae) 57g
Herba pegani harmalae 54g Folium Craibiodendri Yunnanensis 51g Flos Wikstroemiae Dolichanthae 49g Folium et Cacumen Viburni Sargentii 47g
Herba Cymbopogonis Citrari 44g Daphne giraldii Nitsche 42g Radix Cudraniae 39g Semen Hoveniae (Fructus Hoveniae) seven 38g
Radix Mori 34g Herba Sarcandrae 32g Herba Anagallidis Arvensis 24g Radix salaciae prinoidis 17g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
The raw material of effective ingredient of the present invention forms and weight is:
Caulis Benincasae 64g Radix Laporteae Macrostachyae 59g Herba Hyperici Sampsonii 55g Caulis fici pumilae (Fructus Fici Pumilae) 54g
Herba pegani harmalae 49g Folium Craibiodendri Yunnanensis 47g Flos Wikstroemiae Dolichanthae 44g Folium et Cacumen Viburni Sargentii 43g
Herba Cymbopogonis Citrari 42g Daphne giraldii Nitsche 39g Radix Cudraniae 37g Semen Hoveniae (Fructus Hoveniae) seven 35g
Radix Mori 32g Herba Sarcandrae 29g Herba Anagallidis Arvensis 22g Radix salaciae prinoidis 14g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case is selected:
Medicine as the treatment cerebral hemorrhage, the routine clinical observation of patients with cerebral hemorrhage 200 that selection is made a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group 100 examples, wherein male's 47 examples at random, women's 53 examples, 41～83 years old age, 60.4 years old mean age, the shortest person of the course of disease 8 months, elder 15 years, average 7.9 years.Matched group 100 examples, male's 48 examples wherein, women's 52 examples, 40～82 years old age, 61.6 years old mean age, the shortest person of the course of disease 7 months, elder 16 years, average 8.3 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken medicine of the present invention, oral, every day 2 times, each 2, warm water delivery service after meal; Within 9 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2～3 courses for the treatment of.
Matched group is taken the refreshment reworking capsule, warm yellow wine or warm water delivery service, every day 2 times, each 4; Within 15 days, be 1 course for the treatment of, the lighter takes effect 3 courses for the treatment of, and the person of being in a bad way is usually invalid.
3, efficacy determination:
(1) cure: sings and symptoms disappears, and can live on one's own life.
(2) produce effects: symptom and sign take a turn for the better, the action of energy cane, and basic living can be taken care of oneself.
(3) effective: symptom and sign take a turn for the better to some extent, substantially can the cane action.
(4) invalid: sings and symptoms is all without improving, and symptom is as front.
4, result:
Select in the treatment group of medicine of the present invention, cure 36 examples, produce effects 33 examples, effective 29 examples, invalid 2 examples, cure rate 36%, total effective rate 98%.
Cure 15 examples, produce effects 19 examples, effective 20 examples, invalid 46 examples, cure rate 15%, total effective rate 54% in matched group.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, Liu, the female, 45 years old, people from Cangzhou, Hebei, the sudden cerebral hemorrhage of patient, because rescuing in time, kept life, but patient left side body movement is limited, and blood pressure does not descend all the time, seeks medical advice everywhere, and it is invalid to control for a long time.Take medicine of the present invention after 1 course for the treatment of, but left half body limbs gentle activity, speech changes to some extent, and memory also strengthens to some extent, takes again medicine of the present invention after 2 courses for the treatment of, and it is normal that hypertension symptom now recovers substantially, lives and also can take care of oneself.
2, fine strain of millet, the man, 57 years old, the Yuncheng, Shanxi people, fell in a swoon suddenly because going to work in the fields, and syncope, be diagnosed as cerebral hemorrhage.Rescue timely symptomatic treatment more than ten days through hospital, patient's facial hemiparalysis, dysphonia, hemiplegia.Take medicine of the present invention after 2 courses for the treatment of, the transference cures such as facial hemiparalysis, dysphonia, language is clear, and walking is freely.
3, poplar, female, 63 years old, people from Shenyang, Liaoning, the patient tumbles because of carelessness, causes the left side cerebral hemorrhage, the doctor considers that the patient is conscious, does not do operation of opening cranium, employing be the method for Drug therapy, patient's right hand, the restriction of foot active receiving, make not energetically at present, after people's special operations, self feels pins and needles in one's hands and feet, freely, through taking medicine of the present invention after 1 course for the treatment of, the right hand can capture thing in its left half body activity, the right crus of diaphragm activity is nimble, can walk down.
4, Huang, the man, 71 years old, people from Dalian, patient's sudden onset, with dizziness, headache, vomiting, disppointment, sialorrhea, distortion of commissure and half body paralysis, incontinence of urination and defecation; Examine as cerebral hemorrhage.Take 1 course for the treatment of of medicine of the present invention, symptom is eased, and continues to take 2 courses for the treatment of, and symptom disappears fully, cures.
5, Jiang, the female, 79 years old, people from Yangzhou, Jiangsu, patient clinical shows as: hemiplegia, the stiff Gou contraction of Ipsilateral, headache dizziness, flushed complexion tinnitus, dry mouth and throat, deep red tongue, yellow and thin fur, stringy pulse are firmly strong; Examine as cerebral hemorrhage.Take 3 courses for the treatment of of Drug therapy of the present invention, symptom disappears fully, cures.Follow up a case by regular visits to, so far without recurrence.
6, Cao, the man, 80 years old, Zhejiang Hangzhou people, patient's dizziness, right hemianesthesia, right lower limb are sent out directly, are jolted on foot, the right hand is dumb; The laboratory examination result is cerebral hemorrhage.Take 1 course for the treatment of of medicine of the present invention, symptom disappears substantially; Continue to take 2 courses for the treatment of, symptom disappears fully, and life can be taken care of oneself.
Claims (5)
1. a medicine for the treatment of cerebral hemorrhage is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
49～74 parts of 53～79 parts of Caulis fici pumilae (Fructus Fici Pumilae)s of 54～79 portions of Herba Hyperici Sampsoniis of 59～84 parts of Radix Laporteae Macrostachyaes of Caulis Benincasae
39～60 parts of 41～64 parts of Folium et Cacumen Viburni Sargentii of 44～69 parts of Flos Wikstroemiae Dolichanthaes of 45～72 parts of Folium Craibiodendri Yunnanensiss of Herba pegani harmalae
7 34～47 parts of 34～54 portions of Semen Hoveniae (Fructus Hoveniae)s of 36～55 parts of Radix Cudraniaes of 39～59 parts of Daphne giraldii Nitsche of Herba Cymbopogonis Citrari
10～29 parts of 19～39 portions of Radix salaciae prinoidiss of 26～42 parts of Herba Anagallidis Arvensiss of 29～44 parts of Herba Sarcandraes of Radix Mori.
2. a kind of medicine for the treatment of cerebral hemorrhage according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
54～66 parts of 55～74 parts of Caulis fici pumilae (Fructus Fici Pumilae)s of 59～75 portions of Herba Hyperici Sampsoniis of 64～79 parts of Radix Laporteae Macrostachyaes of Caulis Benincasae
43～57 parts of 44～62 parts of Folium et Cacumen Viburni Sargentii of 47～64 parts of Flos Wikstroemiae Dolichanthaes of 49～69 parts of Folium Craibiodendri Yunnanensiss of Herba pegani harmalae
7 35～44 parts of 37～49 portions of Semen Hoveniae (Fructus Hoveniae)s of 39～52 parts of Radix Cudraniaes of 42～54 parts of Daphne giraldii Nitsche of Herba Cymbopogonis Citrari
14～24 parts of 22～29 portions of Radix salaciae prinoidiss of 29～39 parts of Herba Anagallidis Arvensiss of 32～41 parts of Herba Sarcandraes of Radix Mori.
3. a kind of medicine for the treatment of cerebral hemorrhage according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
57～65 parts of 59～69 parts of Caulis fici pumilae (Fructus Fici Pumilae)s of 64～70 portions of Herba Hyperici Sampsoniis of 69～74 parts of Radix Laporteae Macrostachyaes of Caulis Benincasae
47～54 parts of 49～59 parts of Folium et Cacumen Viburni Sargentii of 51～59 parts of Flos Wikstroemiae Dolichanthaes of 54～64 parts of Folium Craibiodendri Yunnanensiss of Herba pegani harmalae
7 38～41 parts of 39～44 portions of Semen Hoveniae (Fructus Hoveniae)s of 42～48 parts of Radix Cudraniaes of 44～49 parts of Daphne giraldii Nitsche of Herba Cymbopogonis Citrari
17～19 parts of 24～26 portions of Radix salaciae prinoidiss of 32～34 parts of Herba Anagallidis Arvensiss of 34～39 parts of Herba Sarcandraes of Radix Mori.
4. a kind of medicine for the treatment of cerebral hemorrhage according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
62 parts of 64 parts of Caulis fici pumilae (Fructus Fici Pumilae)s of 67 portions of Herba Hyperici Sampsoniis of 72 parts of Radix Laporteae Macrostachyaes of Caulis Benincasae
50 parts of 54 parts of Folium et Cacumen Viburni Sargentii of 55 parts of Flos Wikstroemiae Dolichanthaes of 59 parts of Folium Craibiodendri Yunnanensiss of Herba pegani harmalae
7 39 parts of 42 portions of Semen Hoveniae (Fructus Hoveniae)s of 45 parts of Radix Cudraniaes of 47 parts of Daphne giraldii Nitsche of Herba Cymbopogonis Citrari
18 parts of 25 portions of Radix salaciae prinoidiss of 33 parts of Herba Anagallidis Arvensiss of 37 parts of Herba Sarcandraes of Radix Mori.
5. the preparation method as the medicine for the treatment of cerebral hemorrhage as described in claim 1～4 any one is characterized in that: comprise following processing step:
(1) Herba Hyperici Sampsonii, Herba pegani harmalae, Flos Wikstroemiae Dolichanthae, Herba Cymbopogonis Citrari, Daphne giraldii Nitsche, Radix Cudraniae, Radix Mori and Herba Sarcandrae are cleaned, put into container, add the distilled water of 8～10 times of amounts, after soaking 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extract; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that 60 ℃ of lower relative densities are 1.10～1.13, standby;
(2) Folium Craibiodendri Yunnanensis and Folium et Cacumen Viburni Sargentii are mixed, carried out pulverization process after mix homogeneously, ground into powder, crossed 160 order fine powders, standby;
(3) Caulis Benincasae, Caulis fici pumilae (Fructus Fici Pumilae) and Herba Anagallidis Arvensis are cleaned, chopping, put into container, strand juice, and filter impurity, stay juice standby;
(4) Radix Laporteae Macrostachyae, Semen Hoveniae (Fructus Hoveniae) seven and Radix salaciae prinoidis are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaim ethanol, filter, and the thick paste that 65 ℃ of lower relative densities of simmer down to are 1.12～1.18, standby;
(5) above-mentioned steps (1)～(4) prepared thick paste, fine powder and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make tablet, obtain the medicine for the treatment of cerebral hemorrhage of the present invention.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104288549A (en) * | 2014-09-26 | 2015-01-21 | 朱晓岩 | Traditional Chinese medicine formula for treating cerebral hemorrhage |
| CN104306601A (en) * | 2014-09-29 | 2015-01-28 | 张波 | Traditional Chinese medicine formula for treating cerebral hemorrhage |
| CN105030919A (en) * | 2015-07-02 | 2015-11-11 | 王厚中 | Medicinal composition for treating cerebral hemorrhage |
| CN105381064A (en) * | 2015-11-16 | 2016-03-09 | 宁国仙霞骨伤医院 | Traditional Chinese medicine composition for treating cerebral hemorrhage |
| CN105456534A (en) * | 2015-12-29 | 2016-04-06 | 青岛昌安达药业有限公司 | Traditional Chinese medicine preparation for treating cerebral hemorrhage |
| CN105560621A (en) * | 2015-12-29 | 2016-05-11 | 青岛昌安达药业有限公司 | Traditional Chinese medicine composition for treating cerebral hemorrhage |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1907396A (en) * | 2006-08-14 | 2007-02-07 | 黄超权 | Medicine for treating cerebral hemorrhage |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1907396A (en) * | 2006-08-14 | 2007-02-07 | 黄超权 | Medicine for treating cerebral hemorrhage |
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| 翁维良: "《中医活血化瘀治疗疑难病》", 31 August 2011, article "脑血管疾病", pages: 45-46,49-52,55-56 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104288549A (en) * | 2014-09-26 | 2015-01-21 | 朱晓岩 | Traditional Chinese medicine formula for treating cerebral hemorrhage |
| CN104306601A (en) * | 2014-09-29 | 2015-01-28 | 张波 | Traditional Chinese medicine formula for treating cerebral hemorrhage |
| CN105030919A (en) * | 2015-07-02 | 2015-11-11 | 王厚中 | Medicinal composition for treating cerebral hemorrhage |
| CN105381064A (en) * | 2015-11-16 | 2016-03-09 | 宁国仙霞骨伤医院 | Traditional Chinese medicine composition for treating cerebral hemorrhage |
| CN105456534A (en) * | 2015-12-29 | 2016-04-06 | 青岛昌安达药业有限公司 | Traditional Chinese medicine preparation for treating cerebral hemorrhage |
| CN105560621A (en) * | 2015-12-29 | 2016-05-11 | 青岛昌安达药业有限公司 | Traditional Chinese medicine composition for treating cerebral hemorrhage |
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