CN103432264B - Chinese medicinal preparation for treating chronic prostatitis - Google Patents
Chinese medicinal preparation for treating chronic prostatitis Download PDFInfo
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- CN103432264B CN103432264B CN201310383038.7A CN201310383038A CN103432264B CN 103432264 B CN103432264 B CN 103432264B CN 201310383038 A CN201310383038 A CN 201310383038A CN 103432264 B CN103432264 B CN 103432264B
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- 208000013507 chronic prostatitis Diseases 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 201000007094 prostatitis Diseases 0.000 title claims abstract description 14
- 239000003814 drug Substances 0.000 claims abstract description 20
- 210000000582 semen Anatomy 0.000 claims abstract description 10
- 241000628997 Flos Species 0.000 claims description 9
- 241001127702 Lysidice <polychaete> Species 0.000 claims description 9
- 150000002333 glycines Chemical class 0.000 claims description 9
- 241000862632 Soja Species 0.000 claims description 2
- 230000001737 promoting effect Effects 0.000 abstract description 8
- 210000004369 blood Anatomy 0.000 abstract description 5
- 239000008280 blood Substances 0.000 abstract description 5
- 230000017531 blood circulation Effects 0.000 abstract description 4
- 230000004087 circulation Effects 0.000 abstract description 4
- 210000003734 kidney Anatomy 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 3
- 206010018866 Haematospermia Diseases 0.000 abstract description 2
- 208000008982 Hemospermia Diseases 0.000 abstract description 2
- 230000008506 pathogenesis Effects 0.000 abstract description 2
- 238000010792 warming Methods 0.000 abstract description 2
- 235000003276 Apios tuberosa Nutrition 0.000 abstract 1
- 241000722826 Ardisia Species 0.000 abstract 1
- 235000003826 Artemisia Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 244000304217 Brassica oleracea var. gongylodes Species 0.000 abstract 1
- 241001346855 Impatiens chinensis Species 0.000 abstract 1
- 240000004752 Laburnum anagyroides Species 0.000 abstract 1
- 241000350318 Lysidice rhodostegia Species 0.000 abstract 1
- 241000219991 Lythraceae Species 0.000 abstract 1
- 241000722273 Saururus cernuus Species 0.000 abstract 1
- 241001300423 Strophostyles Species 0.000 abstract 1
- 244000290970 Tetrapanax papyrifer Species 0.000 abstract 1
- 235000017537 Vaccinium myrtillus Nutrition 0.000 abstract 1
- 244000078534 Vaccinium myrtillus Species 0.000 abstract 1
- 244000030166 artemisia Species 0.000 abstract 1
- 235000009052 artemisia Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 description 12
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 210000000265 leukocyte Anatomy 0.000 description 5
- 208000004880 Polyuria Diseases 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010061339 Perineal pain Diseases 0.000 description 1
- 208000005214 Poroma Diseases 0.000 description 1
- 206010046555 Urinary retention Diseases 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000000881 depressing effect Effects 0.000 description 1
- 201000001013 eccrine acrospiroma Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 208000001786 gonorrhea Diseases 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 229960001699 ofloxacin Drugs 0.000 description 1
- 210000002640 perineum Anatomy 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 210000002307 prostate Anatomy 0.000 description 1
- 208000026455 prostate symptom Diseases 0.000 description 1
- 210000004908 prostatic fluid Anatomy 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 208000015993 reproductive system symptom Diseases 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese medicinal preparation for treating chronic prostatitis. The chronic prostatitis belongs to the categories of blennorrhagia, turbid semen, leukorrhagia sponaneous emission, hematospermia and the like in Chinese medicine, and the common pathogenesis of the chronic prostatitis includes wet, hot, stasis and weak aspects. The Chinese medicinal preparation is prepared by adding water to decoct the Chinese medicaments including asiatic bilberry, franchet's pea tree flower, radices morindae, kohlrabi, artemisia capillaries, chinese lizardtail rhizome, fortune loosestrife herb, lysidice rhodostegia, impatiens chinensis, tiny ardisia, wild beans, tetrapanax papyriferus root and dried orange peel, which have effects of warming kidney yang, promoting blood circulation to remove blood stasis, clearing away heat to remove dampness, promoting qi circulation to remove obstruction in collaterals and eliminating wetness to discharge pus, into a decoction. Clinical tests show that the total effective rate reaches 93.8% which is obviously superior to that of a control group, so that the Chinese medicinal preparation is worthy of clinical popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of chronic prostatitis.
Background technology
Chronic prostatitis is male adult common disease, and the male who is apt to occur in 20-40 year is between twenty and fifty, and sickness rate is very high, and main manifestations is the aspects such as pain, urinary tract symptom, reproductive system symptom, spirit depressing, is usually difficult to radical cure.That chronic prostatitis is generally divided into is bacillary, non-bacterial and pelvic cavity perineal pain three classes.Complicated clinical manifestation, symptom is not true to type more.This disease has slow, the touching difficulty of morbidity more, and the feature of outbreak is repeatedly having a strong impact on quality of life of male patient.At present, desirable medicine without comparison also clinically, applicant is through clinical trial for many years, the good curative effect of utilizing treatment by Chinese herbs chronic prostatitis to obtain.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of chronic prostatitis.Chronic prostatitis belongs to the categories such as motherland's medical science " gonorrhea ", " essence turbid ", " excessive in vain ", " hemospermia ", and that the common pathogenesis of generation of primary disease has is wet, hot, the stasis of blood, empty four ends.The traditional Chinese medical science thinks that Therapeutic Principle is warming and recuperating the kidney-YANG, blood circulation promoting and blood stasis dispelling, removing damp-heat, promoting of the circulation of QI and removing the obstruction in the collaterals, eliminating dampness by diuresis evacuation of pus.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment chronic prostatitis is made by the Chinese medicine of following weight portion: Fructus Vaccinii Bracteati 12-16 part, Flos Caraganae Franchetianae 3-15 part, Radix Morindae Officinalis 5-15 part, Corm Brassicae caulorapae 30-50 part,, Herba Artemisiae Scopariae 15-20 part, Rhizoma Saururi 15-30 part, Herba Lysimachiae Fortunei 15-25 part, Radix Lysidices rhodostegiae 15-25 part, Herba Impatientis Chinensis 9-13 part, Herba Ardisiae Pusillae 5-15 part, Semen glycines sojae 15-25 part, Radix tetrapanacis Koch 30-60 part, Pericarpium Citri Reticulatae 3-9 part.
Preferably, 15 parts of Fructus Vaccinii Bracteati, 10 parts of Flos Caraganae Franchetianae, 10 parts of Radix Morindae Officinaliss, 40 parts of Corm Brassicae caulorapaes, 18 parts of Herba Artemisiae Scopariae, 24 parts of Rhizoma Saururis, 20 parts of Herba Lysimachiae Fortuneis, 20 parts of Radix Lysidices rhodostegiaes, 11 parts of Herba Impatientis Chinensis, 10 parts of Herba Ardisiae Pusillaes, 20 parts of Semen glycines sojaes, 45 parts of Radix tetrapanacis Kochs, 5 parts of Pericarpium Citri Reticulataes.
Preparation method is made decoction by above-mentioned Chinese medicine decocting.
In side: Fructus Vaccinii Bracteati, Flos Caraganae Franchetianae QI invigorating kidney tonifying, supplementing the kidney to control the nocturnal, strong muscle improving eyesight; Radix Morindae Officinalis kidney-replenishing, wind-damp dispelling; Corm Brassicae caulorapae inducing diuresis to remove edema, and spleen; Herba Artemisiae Scopariae, Rhizoma Saururi heat-clearing and toxic substances removing, expelling wind and removing dampness; Herba Lysimachiae Fortunei dispel the wind circulation of qi promoting, promoting blood circulation to remove blood stasis; Radix Lysidices rhodostegiae eliminating stasis to stop pain; Herba Impatientis Chinensis, Herba Ardisiae Pusillae blood circulation promoting and blood stasis dispelling; Detumescence and apocenosis.Semen glycines sojae liver and kidney tonifying, the removing toxic substances of dispeling the wind; Radix tetrapanacis Koch, Pericarpium Citri Reticulatae promoting the circulation of QI to induce diuresis; Regulating qi-flowing for strengthening spleen, dampness in tune.
Clinical data
1, this group of physical data patient 83 examples, are out-patient, by table of random number, case are divided into treatment group 42 example and matched group 41 examples at random.25～48 years old treatment group age, average 35.6 years old, the course of disease 6 months～2 years.The matched group age is 26～49 years old, average 36.5 years old, and the course of disease 6 months～2 years.Two groups of patient's comparisons aspect age, the course of disease, no significant difference (P > 0.05), has comparability.
2, diagnostic criteria (1) has frequent micturition, dysurea, residual urine sense, and perineum, hypogastric region and anus around pain are uncomfortable; (2) digital rectal examination: the normal or tenderness of prostate, or touch irregular poroma; (3) prostatic fluid (EPS) microscopy: leukocyte > 10/HP, lecithin reduces; (4) course of disease is more than 3 months.The chronic prostate symptom integral index proposing in 1999 with reference to America NI H quantizes symptom score.Its symptom comprises pain symptom, the symptom of urinating, quality of life 3 aspects 13 events, set up from 0～3 minute 4 level, evaluate each symptom degree (asymptomatic: 0 minute, light: 1 minute, in: 2 minutes, heavy: 3 minutes).
3, Therapeutic Method treatment group is taken Chinese medicine preparation of the present invention, takes Fructus Vaccinii Bracteati 15g, Flos Caraganae Franchetianae 10g, Radix Morindae Officinalis 10g, Corm Brassicae caulorapae 40g, Herba Artemisiae Scopariae 18g, Rhizoma Saururi 24g, Herba Lysimachiae Fortunei 20g, Radix Lysidices rhodostegiae 20g, Herba Impatientis Chinensis 11g, Herba Ardisiae Pusillae 10g, Semen glycines sojae 20g, Radix tetrapanacis Koch 45g, Pericarpium Citri Reticulatae 5g.Decocting becomes decoction, and potion, divided and sooner or later took for 2 times every day; The oral QIANLIETAI JIAONANG of matched group, 2 times/day, 4 tablets/time; Add ofloxacin capsule, 2 times/day, 200mg/ time.Two groups all serve on 2 months 1 course for the treatment of.
4, criterion of therapeutical effect clinical cure: symptom score reduces more than 90%, 10/HP of EPS leukocyte count <, digital rectal examination tenderness disappears, and quality is normal or approach normal; Effective: symptom score reduces 70%～89%, EPS leukocyte count and obviously reduces, leukocyte numerical value is front reduces 1/2, or 15/HP of <, and digital rectal examination tenderness and quality all make moderate progress; Effective: symptom score reduces 35%～69%, EPS leukocyte count and reduces to some extent; Invalid: sings and symptoms has no significant change, symptom score reduces < 35% or unchanged, or increases the weight of.
5, curative effect comparison after the course for the treatment of of two groups of therapeutic outcomes treatment, treatment group 42 examples, wherein cure 12 examples (28.6%), effective 18 examples (42.8%), effective 10 examples (23.8%), invalid 2 examples (4.8%), total effective rate 93.8%; Matched group 41 examples, wherein cure 3 examples (7.3%), effective 12 examples (29.3%), effective 11 examples (26.8%), invalid 15 examples (36.6%), total effective rate 63.4%.Two groups of comparisons, treatment group cure rate, total effective rate are obviously better than matched group, have comparability (P < 0.05).
The specific embodiment
Embodiment mono-: take Fructus Vaccinii Bracteati 15g, Flos Caraganae Franchetianae 10g, Radix Morindae Officinalis 10g, Corm Brassicae caulorapae 40g, Herba Artemisiae Scopariae 18g, Rhizoma Saururi 24g, Herba Lysimachiae Fortunei 20g, Radix Lysidices rhodostegiae 20g, Herba Impatientis Chinensis 11g, Herba Ardisiae Pusillae 10g, Semen glycines sojae 20g, Radix tetrapanacis Koch 45g, Pericarpium Citri Reticulatae 5g.Above-mentioned Chinese medicine decocting is made to decoction.
Embodiment bis-: take Fructus Vaccinii Bracteati 16g, Flos Caraganae Franchetianae 3g, Radix Morindae Officinalis 5g, Corm Brassicae caulorapae 30g, Herba Artemisiae Scopariae 20g, Rhizoma Saururi 15g, Herba Lysimachiae Fortunei 25g, Radix Lysidices rhodostegiae 15g, Herba Impatientis Chinensis 13g, Herba Ardisiae Pusillae 15g, Semen glycines sojae 25g, Radix tetrapanacis Koch 60g, Pericarpium Citri Reticulatae 9g, above-mentioned Chinese medicine decocting is made to decoction.
Embodiment tri-: take Fructus Vaccinii Bracteati 12g, Flos Caraganae Franchetianae 15g, Radix Morindae Officinalis 15g, Corm Brassicae caulorapae 50g, Herba Artemisiae Scopariae 15g, Rhizoma Saururi 30g, Herba Lysimachiae Fortunei 15g, Radix Lysidices rhodostegiae 15g, Herba Impatientis Chinensis 9g, Herba Ardisiae Pusillae 5g, Semen glycines sojae 15g, Radix tetrapanacis Koch 30g, Pericarpium Citri Reticulatae 3g, above-mentioned Chinese medicine decocting is made to decoction.
Claims (2)
1. treat a Chinese medicine preparation for chronic prostatitis, it is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Fructus Vaccinii Bracteati 12-16 part, Flos Caraganae Franchetianae 3-15 part, Radix Morindae Officinalis 5-15 part, Corm Brassicae caulorapae 30-50 part, Herba Artemisiae Scopariae 15-20 part, Rhizoma Saururi 15-30 part, Herba Lysimachiae Fortunei 15-25 part, Radix Lysidices rhodostegiae 15-25 part, Herba Impatientis Chinensis 9-13 part, Herba Ardisiae Pusillae 5-15 part, Semen glycines sojae 15-25 part, Radix tetrapanacis Koch 30-60 part, Pericarpium Citri Reticulatae 3-9 part.
2. a kind of Chinese medicine preparation for the treatment of chronic prostatitis according to claim 1, is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: 15 parts of Fructus Vaccinii Bracteati, 10 parts of Flos Caraganae Franchetianae, 10 parts of Radix Morindae Officinaliss, 40 parts of Corm Brassicae caulorapaes, 18 parts of Herba Artemisiae Scopariae, 24 parts of Rhizoma Saururis, 20 parts of Herba Lysimachiae Fortuneis, 20 parts of Radix Lysidices rhodostegiaes, 11 parts of Herba Impatientis Chinensis, 10 parts of Herba Ardisiae Pusillaes, 20 parts of Semen glycines sojaes, 45 parts of Radix tetrapanacis Kochs, 5 parts of Pericarpium Citri Reticulataes.
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| CN103989791B (en) * | 2014-06-13 | 2016-04-06 | 李莹莹 | A kind of compound Chinese medicinal preparation for the treatment of chronic prostatitis |
Citations (3)
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| CN1817036A (en) * | 2003-07-08 | 2006-08-09 | 皇家飞利浦电子股份有限公司 | Motion-compensated image signal interpolation |
| CN101496877A (en) * | 2009-03-13 | 2009-08-05 | 吕伟 | Chinese-medicine mixture for treating prostatitis |
| CN102240370A (en) * | 2011-06-15 | 2011-11-16 | 王少云 | Chinese medicinal composition for treating benign prostatic hyperplasia and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2008113118A1 (en) * | 2007-03-16 | 2008-09-25 | Medcina Group Pty Ltd | Compositions and methods for treating male infertility |
| KR101152910B1 (en) * | 2009-11-16 | 2012-06-05 | 김관태 | Processfood of a cherry tomato for improving a prostate function and the manufacturing method |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1817036A (en) * | 2003-07-08 | 2006-08-09 | 皇家飞利浦电子股份有限公司 | Motion-compensated image signal interpolation |
| CN101496877A (en) * | 2009-03-13 | 2009-08-05 | 吕伟 | Chinese-medicine mixture for treating prostatitis |
| CN102240370A (en) * | 2011-06-15 | 2011-11-16 | 王少云 | Chinese medicinal composition for treating benign prostatic hyperplasia and preparation method thereof |
Non-Patent Citations (3)
| Title |
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| 沈楚翘等.血精证治.《安徽中医学院学报》.1984,(第4期),第34-35页. |
| 范欣生.茵陈陈皮茶.《肝胆病妙用中药》.江苏科学技术出版社,1998,(第1版),第80页. * |
| 血精证治;沈楚翘等;《安徽中医学院学报》;19841231(第4期);第34-35页 * |
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Effective date of registration: 20160104 Address after: 130000, 1 overseas street, Jilin, Changchun Patentee after: Changchun Haiwai Pharmaceutical(Group) Co., Ltd. Address before: 261041 Shandong Province, Weifang city Kuiwei District in the State Road 1055, Weifang Hospital of Traditional Chinese Medicine Patentee before: Yan Bo |