CN104825916A - Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating rheumatoid arthritis. The composition is composed of tripterygium wilfordii, monkshood, aconitum kusnezoffii, honeysuckle stem, caulis sinomenii, Chinese angelica, notopterygium root, cassia twig, kadsura pepper stem, achyranthes root, menispermaceae, coix seed, cortex illicii, safflower, ligusticum wallichii, and licorice. The preparation method comprises the following steps: washing the raw materials, soaking tripterygium wilfordii, monkshood, and aconitum kusnezoffii for 60 to 70 minutes, then pouring out the water, refilling water, transferring the substances to a decocting device, starting the decocting device, heating the water to boil by strong fire, then decocting the substances for 90 to 120 minutes by slow fire; adding the rest raw materials into the decocting device, heating the water to boil by strong fire again, then decocting the substances by slow fire until 450 to 500 parts by weight of water is left in the decocting device, stopping the decocting device, and filtering to obtain the filtrate. The invention aims to provide a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method thereof. The provided traditional Chinese medicine composition can effectively treat rheumatoid arthritis and at the same time the side effect to human body is reduced.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, particularly a kind of Chinese medicine composition for the treatment of rheumatoid arthritis and preparation method thereof.
Background technology
Rheumatoid arthritis is the autoimmune inflammation mainly involving the multisystem of periarticular that a kind of cause of disease is still not clear, English abbreviation RA.The Major Clinical feature of rheumatoid arthritis is symmetric polyarthritis, based on periarticular infringement, show as chronic swelling, pain, morning stiff and dysfunction, namely have destruction of joint in early days, cause joint deformity, tetanic and dysfunction late period.Rheumatoid arthritis typical clinical is characterized as: arthralgia, arthroncus, moving obstacle, osteoporosis, and joint deformity is the Late manifestations of primary disease.
Market has the Western medicine of a lot of rheumatoid arthritis, over the course for the treatment of, Western medicine can comparatively effectively preventing be ailing, but, general with the very difficult elimination of western medicine rheumatoid arthritis, and Western medicine is more expensive, the more difficult consumption of ordinary people.And treatment by Chinese herbs adopts determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, generally all have the curative effect of better treating both the principal and secondary aspects of a disease compared with Western medicine, and price of medicinal material is comparatively acceptant.
The information being disclosed in this background technology part is only intended to increase the understanding to general background of the present invention, and should not be regarded as admitting or imply in any form that this information structure has been prior art that persons skilled in the art are known.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of rheumatoid arthritis and preparation method thereof, while effectively treating rheumatoid arthritis, alleviate drug effect to human injury.
Another object of the present invention is to provide an a kind of preparation method being used for the treatment of the Chinese medicine composition of rheumatoid arthritis, preparation method of the present invention is simple to operate, easy, and the cycle is shorter, and production cost is low.
For achieving the above object, technical scheme provided by the invention is as follows:
Treat a Chinese medicine composition for rheumatoid arthritis, according to ratio of weight and number, be made up of following component raw material: Radix Tripterygii Wilfordii 10-20 part, Radix Aconiti 6-9 part, Radix Aconiti Kusnezoffii 6-9 part, Caulis Lonicerae 10-15 part, Caulis Sinomenii 10-15 part, Radix Angelicae Sinensis 8-10 part, Rhizoma Et Radix Notopterygii 8-12 part, Ramulus Cinnamomi 6-8 part, Caulis Piperis Kadsurae 6-8 part, Radix Achyranthis Bidentatae 6-8 part, Radix Stephaniae Tetrandrae 10-15 part, Semen Coicis 20-25 part, Cortex Illicii 6-9 part, Flos Carthami 10-12 part, Rhizoma Chuanxiong 6-9 part, Radix Glycyrrhizae 9-12 part.
Preferably, Radix Tripterygii Wilfordii 20 parts, Radix Aconiti 7 parts, Radix Aconiti Kusnezoffii 7 parts, Caulis Lonicerae 15 parts, Caulis Sinomenii 15 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Et Radix Notopterygii 12 parts, Ramulus Cinnamomi 6 parts, Caulis Piperis Kadsurae 6 parts, Radix Achyranthis Bidentatae 6 parts, Radix Stephaniae Tetrandrae 15 parts, Semen Coicis 25 parts, Cortex Illicii 6 parts, 10 parts, Flos Carthami, Rhizoma Chuanxiong 9 parts, 10 parts, Radix Glycyrrhizae.
A preparation method for the Chinese medicine composition for the treatment of rheumatoid arthritis as above, comprises following operating procedure:
(1) take required each component raw material and clean, Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii are soaked 60 ~ 70min, the water after soaking is outwelled, rejoin 1000 weight parts waters, put into decoction vessel together, open fire, first be heated to boiling with high heat, then use slow fire boiling 90 ~ 120min instead;
(2) will add in the decoction vessel of slow fire boiling 90 ~ 120min in step (1) except Radix Tripterygii Wilfordii, Radix Aconiti, all the other component raw material of Radix Aconiti Kusnezoffii, again decoct to boiling with high heat, after use instead culture decoct Yu to decoction vessel close after 450 ~ 500 parts of weight parts waters fiery, filter, get filtrate, to obtain final product.
Preferably, decocting device is put into again after other component raw material in step (2) except Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii need soak 30 ~ 40min.
Namely above-mentioned decoction gained is calculated as potion medicine, and the instructions of taking of Chinese medicine of the present invention is: potion on the one, and potion divides the morning, noon and afternoon to take for 3 times, within 1 month, is a course for the treatment of.Treatments period should be taken food light, digestible food, and keep happy, attention can not be engaged in strenuous exercise, other all Chinese medicine and western medicine of stopping using.
The present invention selects Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii, Caulis Lonicerae, Caulis Sinomenii, Radix Angelicae Sinensis, Rhizoma Et Radix Notopterygii, Ramulus Cinnamomi, Caulis Piperis Kadsurae, Radix Achyranthis Bidentatae, Radix Stephaniae Tetrandrae, Semen Coicis, Cortex Illicii, Flos Carthami, Rhizoma Chuanxiong, and Radix Glycyrrhizae combines, and is made by these drug regimens each efficacy of drugs produce synergism.
In the middle of Chinese medicine composition of the present invention, Radix Tripterygii Wilfordii expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, reducing swelling and alleviating pain, parasite killing detoxifies; Radix Aconiti, Radix Aconiti Kusnezoffii have the effect of good antiinflammatory action and stronger analgesia, anti-allergy action and adrenocorticotropin sample; Caulis Lonicerae heat-clearing and toxic substances removing, dispelling wind and removing obstruction in the collateral; Caulis Sinomenii expelling wind and removing dampness, inducing diuresis to remove edema; Chinese angelica blood supplementing and blood, menstruction regulating and pain relieving, moisturizes laxation; Rhizoma Et Radix Notopterygii falls apart exterior cold, wind-damp dispelling, sharp joint; Ramulus Cinnamomi expelling cold and relieving exterior syndrome; Caulis Piperis Kadsurae wind-damp dispelling, the meridian dredging, regulates the flow of vital energy; Radix Achyranthis Bidentatae blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards; Radix Stephaniae Tetrandrae inducing diuresis to remove edema, wind-expelling pain-stopping; Semen Coicis dries except wind, clearing away heat and discharging pus, eliminating impediment pain relieving; Cortex Illicii expelling wind and removing dampness, promoting the circulation of QI to relieve pain; Flos Carthami promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping; Radix Glycyrrhizae and middle emergency, coordinating the actions of various ingredients in a prescription.In side, all medicines and use, play expelling wind and removing dampness altogether, blood-activating and qi-promoting, effect of reducing swelling and alleviating pain, jointly reaches the object for the treatment of rheumatoid arthritis.
Compared with prior art, the present invention has following beneficial effect:
The pharmaceutical purity that Chinese medicine composition of the present invention adopts is natural, pollution-free, for rheumatoid arthritis, there is good curative effect, and, after the present invention prepares gained Chinese medicine composition patient use, minimum to the side effect of patient, further, the present invention prepares the method for this Chinese medicine composition, the effective ingredient in medical material can better be extracted, prepare gained medicine effect better.
Detailed description of the invention
Be described in detail below in conjunction with detailed description of the invention, but be to be understood that protection scope of the present invention not by the restriction of detailed description of the invention.
Embodiment 1
In units of g, take required each component raw material: Radix Tripterygii Wilfordii 20g, Radix Aconiti 7g, Radix Aconiti Kusnezoffii 7g, Caulis Lonicerae 15g, Caulis Sinomenii 15g, Radix Angelicae Sinensis 10g, Rhizoma Et Radix Notopterygii 12g, Ramulus Cinnamomi 6g, Caulis Piperis Kadsurae 6g, Radix Achyranthis Bidentatae 6g, Radix Stephaniae Tetrandrae 15g, Semen Coicis 25g, Cortex Illicii 6g, Flos Carthami 10g, Rhizoma Chuanxiong 9g, Radix Glycyrrhizae 10g, other component raw material except Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii need be soaked 30min, and the water of immersion is outwelled, and the component raw material medical material after immersion is kept for subsequent use; Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii are cleaned and then soak 60min, the water after soaking is outwelled, rejoins 1000g pure water, put into decocting medicine pot together, open fire, be first heated to boiling with high heat, then use slow fire boiling 120min instead; Soakedly add in decocting medicine pot except all the other component raw material except Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii by above-mentioned, again decoct to boiling with high heat, then use culture instead and decoct close fire after remaining 500g pure water to decocting medicine pot, filter with 2 layers of clean gauze, get filtrate, to obtain final product.
Embodiment 2
In units of g, take required each component raw material: Radix Tripterygii Wilfordii 10g, Radix Aconiti 6g, Radix Aconiti Kusnezoffii 6g, Caulis Lonicerae 10g, Caulis Sinomenii 10g, Radix Angelicae Sinensis 8g, Rhizoma Et Radix Notopterygii 8g, Ramulus Cinnamomi 7g, Caulis Piperis Kadsurae 7g, Radix Achyranthis Bidentatae 7g, Radix Stephaniae Tetrandrae 10g, Semen Coicis 20g, Cortex Illicii 8g, Flos Carthami 11g, Rhizoma Chuanxiong 6g, Radix Glycyrrhizae 9g, other component raw material except Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii need be soaked 40min, and the water of immersion is outwelled, and the component raw material medical material after immersion is kept for subsequent use; Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii are cleaned and then soak 70min, the water after soaking is outwelled, rejoins 1000g pure water, put into decocting medicine pot together, open fire, be first heated to boiling with high heat, then use slow fire boiling 90min instead; Soakedly add in decocting medicine pot except all the other component raw material except Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii by above-mentioned, again decoct to boiling with high heat, then use culture instead and decoct close fire after remaining 450g pure water to decocting medicine pot, filter with 3 layers of clean gauze, get filtrate, to obtain final product.
Embodiment 3
In units of g, take required each component raw material: Radix Tripterygii Wilfordii 15g, Radix Aconiti 9g, Radix Aconiti Kusnezoffii 9g, Caulis Lonicerae 13g, Caulis Sinomenii 12g, Radix Angelicae Sinensis 9g, Rhizoma Et Radix Notopterygii 10g, Ramulus Cinnamomi 8g, Caulis Piperis Kadsurae 8g, Radix Achyranthis Bidentatae 8g, Radix Stephaniae Tetrandrae 13g, Semen Coicis 22g, Cortex Illicii 9g, Flos Carthami 12g, Rhizoma Chuanxiong 8g, Radix Glycyrrhizae 12g, other component raw material except Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii need be soaked 35min, and the water of immersion is outwelled, and the component raw material medical material after immersion is kept for subsequent use; Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii are cleaned and then soak 65min, the water after soaking is outwelled, rejoins 1000g pure water, put into decocting medicine pot together, open fire, be first heated to boiling with high heat, then use slow fire boiling 105min instead; Soakedly add in decocting medicine pot except all the other component raw material except Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii by above-mentioned, again decoct to boiling with high heat, then use culture instead and decoct close fire after remaining 475g pure water to decocting medicine pot, filter with 2 layers of clean gauze, get filtrate, to obtain final product.
Curative effect is investigated
For checking therapeutic effect of the present invention, choosing 72 routine rheumatoid arthritis persons and giving the traditional Chinese medicine composition for treating that the above embodiment of the present invention prepares gained; Wherein male 40 example, women 32 example, age 38-65 year, 53 years old mean age.Course of disease 0.5-12.Clinical manifestation is mainly arthralgia, arthroncus, osteoporosis, severe patient moving obstacle, joint deformity.
Efficacy assessment standard:
(1) cure: after taking 1 course for the treatment of of Chinese medicine composition of the present invention, arthralgia, arthroncus disappear, and moving obstacle, joint deformity part are clearly better;
(2) effective: after taking 1 course for the treatment of of Chinese medicine composition of the present invention, arthralgia, arthroncus alleviate, and moving obstacle, joint deformity part progressively take a turn for the better;
(3) invalid: after taking 1 course for the treatment of of Chinese medicine composition of the present invention, arthralgia, arthroncus, moving obstacle, joint deformity are without any improvement.
Result: after 72 routine rheumatoid arthritis persons take 1 course for the treatment of of Chinese medicine composition of the present invention, cures 30 examples, effective 37 examples, invalid 5 examples.Total effective rate is 93%.
Model case:
Case 1
Wang certain, man, 65 years old, retired employees, suffered from rheumatoid arthritis more than 5 years, and both hands ossify, swelling pain, and slight Hypertension is all invalid through in many ways curing.After taking 1 course for the treatment of of Chinese medicine composition of the embodiment of the present invention 1, arthroncus, pain phenomenon disappear, and blood pressure recovers normal substantially.Continue to take 2 courses for the treatment of, rheumatoid arthritis is thoroughly fully recovered again.Recurrence that so far there are no.
Case 2
Chen, female, 68 years old, retired cadre, in the morning in a winter in 2013, feel suddenly uncomfortable from head to foot, astasia, household lost no time to be sent to hospital, and chemical examination is diagnosed as rheumatoid arthritis on inspection.From then on, there is total numbness, myasthenia of limbs, hurt like hell, difficulty in walking very soon.More seriously each joint is red and swollen, is out of shape gradually, stiff, amyotrophy, tetanic, can't take care of oneself.Although have employed medicine and the treatment of multiple rheumatic arthritis, have no improvement always.After taking 2 courses for the treatment of of Chinese medicine composition of the embodiment of the present invention 2 after being introduced, surprisingly find that health is not numb, pain alleviates, and extremity also can do some actions by a small margin.After continuing to take 4 courses for the treatment of of Chinese medicine composition of the embodiment of the present invention 3, arthroncus, pain phenomenon all disappear, and also can walk freely, have recovered the self-care ability of living.Recurrence that so far there are no.
The aforementioned description to concrete exemplary of the present invention is to illustrate and the object of illustration.These descriptions not want the present invention to be defined as disclosed precise forms, and obviously, according to above-mentioned instruction, can much change and change.The object selected exemplary embodiment and describe is to explain certain principles of the present invention and practical application thereof, thus those skilled in the art can be realized and utilize various different exemplary of the present invention and various different selection and change.Scope of the present invention is intended to limited by claims and equivalents thereof.
Claims (4)
1. treat a Chinese medicine composition for rheumatoid arthritis, it is characterized in that, according to ratio of weight and number, be made up of following component raw material: Radix Tripterygii Wilfordii 10-20 part, Radix Aconiti 6-9 part, Radix Aconiti Kusnezoffii 6-9 part, Caulis Lonicerae 10-15 part, Caulis Sinomenii 10-15 part, Radix Angelicae Sinensis 8-10 part, Rhizoma Et Radix Notopterygii 8-12 part, Ramulus Cinnamomi 6-8 part, Caulis Piperis Kadsurae 6-8 part, Radix Achyranthis Bidentatae 6-8 part, Radix Stephaniae Tetrandrae 10-15 part, Semen Coicis 20-25 part, Cortex Illicii 6-9 part, Flos Carthami 10-12 part, Rhizoma Chuanxiong 6-9 part, Radix Glycyrrhizae 9-12 part.
2. Chinese medicine composition according to claim 1, is characterized in that, according to ratio of weight and number, be made up of following component raw material: Radix Tripterygii Wilfordii 20 parts, Radix Aconiti 7 parts, Radix Aconiti Kusnezoffii 7 parts, Caulis Lonicerae 15 parts, Caulis Sinomenii 15 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Et Radix Notopterygii 12 parts, Ramulus Cinnamomi 6 parts, Caulis Piperis Kadsurae 6 parts, Radix Achyranthis Bidentatae 6 parts, Radix Stephaniae Tetrandrae 15 parts, Semen Coicis 25 parts, Cortex Illicii 6 parts, 10 parts, Flos Carthami, Rhizoma Chuanxiong 9 parts, 10 parts, Radix Glycyrrhizae.
3. a preparation method for the Chinese medicine composition for the treatment of rheumatoid arthritis as claimed in claim 1, is characterized in that, comprise following operating procedure:
(1) take required each component raw material and clean, Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii are soaked 60 ~ 70min, the water after soaking is outwelled, rejoin 1000 weight parts waters, put into decoction vessel together, open fire, first be heated to boiling with high heat, then use slow fire boiling 90 ~ 120min instead;
(2) will add in the decoction vessel of slow fire boiling 90 ~ 120min in step (1) except Radix Tripterygii Wilfordii, Radix Aconiti, all the other component raw material of Radix Aconiti Kusnezoffii, again decoct to boiling with high heat, after use instead culture decoct Yu to decoction vessel close after 450 ~ 500 parts of weight parts waters fiery, filter, get filtrate, to obtain final product.
4. preparation method according to claim 3, is characterized in that: put into decocting device again after other component raw material in step (2) except Radix Tripterygii Wilfordii, Radix Aconiti, Radix Aconiti Kusnezoffii need soak 30 ~ 40min.
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| CN105748664A (en) * | 2016-03-28 | 2016-07-13 | 天峨县平昌生态农业有限公司 | Traditional Chinese medicine preparation for treating rheumatoid arthritis and preparation method of traditional Chinese medicine preparation |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105748664A (en) * | 2016-03-28 | 2016-07-13 | 天峨县平昌生态农业有限公司 | Traditional Chinese medicine preparation for treating rheumatoid arthritis and preparation method of traditional Chinese medicine preparation |
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