CN103393857B - Drug for curing hepatitis and preparation method thereof - Google Patents
Drug for curing hepatitis and preparation method thereof Download PDFInfo
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- CN103393857B CN103393857B CN201310361517.9A CN201310361517A CN103393857B CN 103393857 B CN103393857 B CN 103393857B CN 201310361517 A CN201310361517 A CN 201310361517A CN 103393857 B CN103393857 B CN 103393857B
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Abstract
The invention discloses a drug for curing hepatitis and a preparation method thereof, and belongs to the field of traditional Chinese medicine. The drug comprises following effective raw materials: whitebackleaf mallotus root, iris japonica thumb, alum, lygodium japonicum, salix matsudana koidz, herb of shady groundsel, triquetrous tadehagi herb, flying squirrel feces, artemisia japonica, fortune holly fern rhizome, phellodendron, hypecoum erectum, cornus officinalis, sago seed, turtle shell and fiveleaf akebia fruit. The drug has the functions of nourishing liver, clearing heat, removing toxicity and tranquilizing by nourishing the heart, and has prominent curative effects on inhibiting and clearing hepatitis virus, adjusting human immunity functions, recovering liver form and functions, and preventing and curing hepatic fibrosis and liver cancer. The drug has the advantages of low cost, user-friendliness, easy absorption, and quick and good curative effect, achieves the goal of curing both the symptom and the root causes, and has no side or toxic effects and a very good curative effect on hepatitis.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and preparation method for the treatment of hepatitis.
Background technology
Hepatitis is the inflammation of liver, and the healthy of people in serious harm, of a great variety due to hepatitis, and the cause of disease of causing a disease is complicated, as treatment in time or therapeutic effect not good, the state of an illness will worsen.Hepatitis, typically refers to by multiple paathogenic factor--as virus, parasite, chemical toxicant, medicine and poisonous substance, ethanol etc., and infringement liver, the cell of liver is damaged, the function of liver suffers damage, and it can cause a series of malaise symptoms of health, and the exception of liver function index.Viral hepatitis (viralhepatitis) be caused by multiple different hepatitis virus one group based on the infectious disease of liver evil, according to etiological diagnosis, hepatitis virus has 5 kinds at least, namely first, second, third, fourth, hepatitis E virus, cause respectively first, second, third, fourth, hepatitis E, i.e. hepatitis A (hepatitis A), hepatitis B (hepatitis B), hepatitis C (hepatitisC), hepatitis D (hepatitis D) and hepatitis E (hepatitis E).Another is called hepatitis G, more rare.Viral hepatitis is mainly through excrement-mouth, blood or body fluid communication, and occur jaundice with tired, loss of appetite, hepatomegaly, abnormal liver function for main manifestations, some cases clinically, symptomless infection is common.
At present, medically to the treatment of hepatitis, main employing be antiviral therapy, the indication having it clear and definite due to antiviral therapy and contraindication, and being subject to the impact of the reasons such as economic condition, the various effect of drugs for the treatment of hepatitis are not very desirable, and treatment time is long, cure rate is low, and side effect is large.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of hepatitis, medicine of the present invention has the effect of keeping fit liver, heat-clearing and toxic substances removing, liver heat removing and eyesight improving, tranquilizing by nourishing the heart, has significant curative effect to suppression and removing hepatitis virus, adjustment immune function of human body, recovery liver morphology and function, control hepatic fibrosis and canceration; Drug therapy cost of the present invention is low, taking convenience, be easy to absorption, instant effect, good effect, reach the object for the treatment of both the principal and secondary aspects of a disease, has no side effect, has good effect to treatment hepatitis.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for hepatitis, raw material composition and the parts by weight of making described effective ingredient are:
Folium Malloti Apeltae 52 ~ 77 parts of Rhizoma Iridis Japonicaes 47 ~ 72 parts of Alumens 46 ~ 72 parts of Spora Lygodii 42 ~ 67 parts
Folium et Cacumen Salicis Matsudanae 38 ~ 65 parts of Herba senecionis nemorensis 37 ~ 62 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s 34 ~ 57 parts of Oletum Trogopteroris 32 ~ 53 parts
Herba Artemisiae Japonicae 29 ~ 49 parts of Cyrtomium fortunei J. Sm.s 26 ~ 45 portions of Cortex Phellodendris 27 ~ 47 parts of Radix Hypecol Erecti 27 ~ 40 parts
Fructus Corni 22 ~ 37 parts of Cycas revoluta Thunb.s 19 ~ 36 parts of Carapax Trionycis 17 ~ 32 parts of Fructus Akebiaes 7 ~ 27 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Folium Malloti Apeltae 57 ~ 72 parts of Rhizoma Iridis Japonicaes 52 ~ 69 parts of Alumens 48 ~ 67 parts of Spora Lygodii 47 ~ 64 parts
Folium et Cacumen Salicis Matsudanae 42 ~ 62 parts of Herba senecionis nemorensis 41 ~ 57 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s 37 ~ 54 parts of Oletum Trogopteroris 36 ~ 50 parts
Herba Artemisiae Japonicae 35 ~ 47 parts of Cyrtomium fortunei J. Sm.s 32 ~ 44 portions of Cortex Phellodendris 30 ~ 42 parts of Radix Hypecol Erecti 28 ~ 37 parts
Fructus Corni 25 ~ 34 parts of Cycas revoluta Thunb.s 22 ~ 32 parts of Carapax Trionycis 20 ~ 27 parts of Fructus Akebiaes 10 ~ 24 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Folium Malloti Apeltae 62 ~ 67 parts of Rhizoma Iridis Japonicaes 57 ~ 63 parts of Alumens 52 ~ 62 parts of Spora Lygodii 50 ~ 60 parts
Folium et Cacumen Salicis Matsudanae 47 ~ 57 parts of Herba senecionis nemorensis 44 ~ 52 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s 42 ~ 52 parts of Oletum Trogopteroris 40 ~ 47 parts
Herba Artemisiae Japonicae 37 ~ 43 parts of Cyrtomium fortunei J. Sm.s 35 ~ 42 portions of Cortex Phellodendris 32 ~ 37 parts of Radix Hypecol Erecti 31 ~ 34 parts
Fructus Corni 27 ~ 32 parts of Cycas revoluta Thunb.s 26 ~ 29 parts of Carapax Trionycis 22 ~ 24 parts of Fructus Akebiaes 12 ~ 19 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Folium Malloti Apeltae 65 parts of Rhizoma Iridis Japonicaes 60 parts of Alumens 57 parts of Spora Lygodii 55 parts
Folium et Cacumen Salicis Matsudanae 52 parts of Herba senecionis nemorensis 48 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s 47 parts of Oletum Trogopteroris 43 parts
Herba Artemisiae Japonicae 40 parts of Cyrtomium fortunei J. Sm.s 38 portions of Cortex Phellodendris 35 parts of Radix Hypecol Erecti 32 parts
Fructus Corni 30 parts of Cycas revoluta Thunb.s 27 parts of Carapax Trionycis 23 parts of Fructus Akebiaes 15 parts.
Treat a preparation method for the medicine of hepatitis, comprise following processing step:
(1) Alumen, Radix Hypecol Erecti, Fructus Corni and Cycas revoluta Thunb. are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 120 order fine powders, for subsequent use;
(2) Rhizoma Iridis Japonicae, Spora Lygodii, Folium et Cacumen Salicis Matsudanae, Herba senecionis nemorensis, Herba Artemisiae Japonicae, Cyrtomium fortunei J. Sm., Cortex Phellodendri and Fructus Akebiae are cleaned, put into container, add the distilled water of 8 ~ 12 times amount, soak after 4 ~ 5 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 50 DEG C is the thick paste of 1.10 ~ 1.14, for subsequent use;
(3) cleaned by Folium Malloti Apeltae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Oletum Trogopterori is put micro-stir-fry in pot, sprays rice vinegar, then fry to micro-dry, surface slightly gloss time take out, dry, grind into powder, cross 200 order fine powders, for subsequent use;
(5) cleaned by Herba Desmodii Triquetri (Herba Tadehagi Triquetri), immerse the alcohol solution dipping 1 ~ 2 hour of 85% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, under filtrate simmer down to 60 DEG C of environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use;
(6) sandy soil put in pot heat, loosen to sandy soil, get Carapax Trionycis and put into pot and fry to the micro-yellow of epidermis, take out sieve and remove sandy soil, put into vinegar basin and slightly soak, every 100 jin with vinegar 30 jin, taking-up is dried, and grinds into powder, mistake 160 order fine powders, for subsequent use;
(7) made for above-mentioned steps (1) ~ (6) fine powder, thick paste and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make capsule, both the medicine for the treatment of hepatitis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Folium Malloti Apeltae: micro-hardship is puckery, flat; Easing the affected liver is invigorated blood circulation, invigorating the spleen for eliminating dampness, solid de-, the anti-inflammation hemostasia of convergence.For chronic hepatitis, hepatosplenomegaly, uterine prolapse, proctoptosis, leucorrhea, edema during pregnancy; Otitis media is controlled in external, furuncle and phyma, traumatic injury, traumatic hemorrhage." Nanning City's medicine will " carries: " heat clearing away, diuretic, wind-damp dispelling, pain relieving; Control stranguria with turbid discharge, hemorrhoid, traumatic injury, snakebite.Antipruritic, detumescence.”
Rhizoma Iridis Japonicae: bitter, cold, slightly poisonous; Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For hepatitis, hepatomegaly, pain in the hepatic region, stomachache, food stagnation distension, laryngopharynx swelling and pain, traumatic injury, relieving constipation by purgation, for constipation." Guizhou medical herbs " carries: " heat-clearing and toxic substances removing, Gu de-, parasite killing.”
Alumen: sour and astringent, cold, poisonous; Return lung, spleen, liver, large intestine, urinary bladder channel.Expectorant, dampness, antidiarrheal, hemostasis, removing toxic substances, parasite killing.Control epilepsy, sore throat, remorse saliva is stopped up very, hepatitis, jaundice, general edema with yellowish skin, taste-blindness rate, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha of the mouth and tongue, skin ulcer hemorrhoid scabies, water, fire, insect bite." Japan hanako materia medica " carries: " except wind goes labor, expectorant is quenched the thirst, and warm water is hidden.Control apoplectic aphasia, scabies.With Fructus Persicae people, the bath of Herba Alii fistulosi soup, can perspire.”
Spora Lygodii: cold in nature, sweet in the mouth; Return bladder, small intestine meridian.Eliminating damp-heat, treating stranguria pain relieving.For pyretic stranguria, sand Stranguria, stranguria with blood, stranguria marked by chyluria, Urethra astringent pain." Jiangxi medical herbs " carries: " heat-clearing and toxic substances removing, promoting urination to remove dampness.Treating the liver is scorching, renal edema, skin eczema, chickenpox, hematuria.Mumps, acute toothache, throat moth, diphtheria, herpes zoster, infantile malnutrition.”
Folium et Cacumen Salicis Matsudanae: mildly bitter flavor, cold in nature.Loose wind, damp eliminating, clearing away damp-heat.Control icterohepatitis, rheumatic arthritis, eczema.
Herba senecionis nemorensis: toil, cold; Enter liver, spleen channel.Heat-clearing and toxic substances removing.Control dysentery, enteritis, hepatitis, conjunctivitis, otitis media, carbuncle treats poison, swelling around the eyes, carbuncle furuncle furunculosis.
Herba Desmodii Triquetri (Herba Tadehagi Triquetri): micro-hardship, puckery, cool.Heat-clearing and toxic substances removing, removing food stagnancy dampness removing, parasite killing is anticorrosion.For preventing heatstroke, cold, fever, laryngopharynx swelling and pain, nephritis, icterohepatitis, enteritis, bacillary dysentery, infantile malnutrition, vomiting during pregnancy, Fructus Ananadis comosi is poisoning, children's's scleroderma.
Oletum Trogopterori: sweet, temperature; Enter liver, spleen channel.Promoting blood circulation to remove blood stasis, parch to black stops blooding.Have a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black controls metrostaxis; Traumatic injury is controlled in external, Serpentis, insect bite wound.Amplification on Canon of Materia Medica carries: " Oletum Trogopterori pass through blood gain merit, can not hemopoietic.Taste and have nebula in the sick eye of people, come and go indefinite, be so blood institute disease also.Lid the heart being responsible for production of blood, blood stored in the liver, liver then can look by blood, and it is contrary to reason that order disease does not control blood.”
Herba Artemisiae Japonicae: bitter in the mouth, micro-sweet, cool in nature.Heat clearing away, removing heat from blood, removing toxic substances.Main summer catches a cold, pulmonary tuberculosis hectic fever, and spitting of blood, children's's infantile malnutrition with fever, epistaxis, has blood in stool, metrorrhagia, leukorrhagia, icterohepatitis, erysipelas, venom." Traditional Chinese Medicine in Sichuan will " carries: " energy clearing away heat from blood, liver-heat, ebb heat.Control cough, sphincter disturbance.”
Cyrtomium fortunei J. Sm.: bitter, is slightly cold; Heat-clearing and toxic substances removing, cooling blood for calming endogenous wind, loose expectorant hemostasis, drives hook, ascarid, silk ribbon, pinworm parasites.Cure cold, calentura macule, acute diseases such as cholera and sunstroke is dirty poisoning, malaria, dysentery, hepatitis, and dizziness due to hyperactivity of liver-YANG is had a headache, hematemesis hematochezia, metrorrhagia, leukorrhagia, acute mastitis, scrofula, traumatic injury." conventional herbtherapy handbook " carries: " removing heat from blood, nourishes blood for endogenous wind stopping, the clear sharp head, removing toxic substances, dissipating blood stasis.Row pestilence when controlling, malaria, scrofula, sore swollen toxin, abdominal pain due to worm stagnation.”
Cortex Phellodendri: bitter, cold; Return kidney, bladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus, stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency." Japan hanako materia medica " carries: " feel at ease except labor, control hectic fever due to YIN-deficiency, wash liver, improving eyesight, many tear, xerostomia, heat in the heart, kill infantile malnutrition worm, control ascarid pained, scabies, processed with honey controls serious epistaxis, and hemorrhoidal hamorrhage rushes down blood, and rear point anxious heat swells and ache.”
Radix Hypecol Erecti: bitter, cold, slightly poisonous.Heat-clearing and toxic substances removing, antitussive pain relieving.Main cold, fever, cough, laryngopharynx swelling and pain, liver-heat conjunctival congestion, hepatitis, cholecystitis, dysentery, arthralgia." Henan Chinese herbal medicine handbook " carries: " heat clearing away, antiinflammatory, pain relieving.”
Fructus Corni: sour, puckery, tepor; Return liver, kidney channel.Liver and kidney tonifying, restrains astringent or styptic treatment for spontaneous sweating, and controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping only collapses, hidroschesis, also has the effect of promoting the production of body fluid to quench thirst in addition.For soreness of waist and knee joint, dizziness and tinnitus, forgetful emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, menoxenia, profuse sweating is collapsed, and interior-heat is quenched one's thirst." Mingyi Bielu " carries: " meaning can be beneficial smart, settling five organs.In addition, Fructus Corni also controls diabetes, and many being equal to the Radix Rehmanniae, Radix Trichosanthis is used.”
Cycas revoluta Thunb.: bitter, puckery, property is put down, poisonous; Return lung, liver, large intestine channel.Suppressing the hyperactive liver blood pressure lowering, relieving cough and expelling phlegm, restrains astringent or styptic treatment for spontaneous sweating.Main hypertension, chronic hepatitis, cough with copious phlegm, dysentery, seminal emission, leucorrhea, traumatic injury, knife injury.
Carapax Trionycis: salty, is slightly cold; Return liver, kidney channel.Nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, brings down a fever except steaming.For fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea ， WEIJIA, chronic malaria malaria with splenomegaly.
Fructus Akebiae: sweet, cold.Liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis.Treating the liver peratodynia, gastric heat food is slow-witted, excessive thirst, dysentery, lumbago, hypochondriac pain, hernia, dysmenorrhea, and uterus drops." Shaanxi Chinese herbal medicine " carries: " Shugan Yishen, invigorating the spleen and regulating the stomach; Control dyspepsia, stomachache, dysentery, hernia, uterus drops.”
The present invention compared with prior art, has following beneficial effect:
1, medicine of the present invention has the effect of keeping fit liver, heat-clearing and toxic substances removing, liver heat removing and eyesight improving, tranquilizing by nourishing the heart, has significant curative effect to suppression and removing hepatitis virus, adjustment immune function of human body, recovery liver morphology and function, control hepatic fibrosis and canceration.
2, low, the taking convenience of Drug therapy cost of the present invention, be easy to absorption, instant effect, good effect, reach the object for the treatment of both the principal and secondary aspects of a disease, have no side effect, to treatment hepatitis, there is good effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Folium Malloti Apeltae 72g Rhizoma Iridis Japonicae 69g Alumen 67g Spora Lygodii 64g
Folium et Cacumen Salicis Matsudanae 62g Herba senecionis nemorensis 57g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 54g Oletum Trogopterori 50g
Herba Artemisiae Japonicae 47g Cyrtomium fortunei J. Sm. 44g Cortex Phellodendri 42g Radix Hypecol Erecti 37g
Fructus Corni 34g Cycas revoluta Thunb. 32g Carapax Trionycis 27g Fructus Akebiae 24g.
Treat a preparation method for the medicine of hepatitis, comprise following processing step:
(1) Alumen, Radix Hypecol Erecti, Fructus Corni and Cycas revoluta Thunb. are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 120 order fine powders, for subsequent use;
(2) Rhizoma Iridis Japonicae, Spora Lygodii, Folium et Cacumen Salicis Matsudanae, Herba senecionis nemorensis, Herba Artemisiae Japonicae, Cyrtomium fortunei J. Sm., Cortex Phellodendri and Fructus Akebiae are cleaned, put into container, add the distilled water of 8 ~ 12 times amount, soak after 4 ~ 5 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 50 DEG C is the thick paste of 1.10 ~ 1.14, for subsequent use;
(3) cleaned by Folium Malloti Apeltae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Oletum Trogopterori is put micro-stir-fry in pot, sprays rice vinegar, then fry to micro-dry, surface slightly gloss time take out, dry, grind into powder, cross 200 order fine powders, for subsequent use;
(5) cleaned by Herba Desmodii Triquetri (Herba Tadehagi Triquetri), immerse the alcohol solution dipping 1 ~ 2 hour of 85% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, under filtrate simmer down to 60 DEG C of environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use;
(6) sandy soil put in pot heat, loosen to sandy soil, get Carapax Trionycis and put into pot and fry to the micro-yellow of epidermis, take out sieve and remove sandy soil, put into vinegar basin and slightly soak, every 100 jin with vinegar 30 jin, taking-up is dried, and grinds into powder, mistake 160 order fine powders, for subsequent use;
(7) made for above-mentioned steps (1) ~ (6) fine powder, thick paste and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make capsule, both the medicine for the treatment of hepatitis of the present invention.
Usage and dosage: oral 3 times of every day, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, usual 2 courses for the treatment of take effect, 3 ~ 4 recoveries from illness course for the treatment of.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Folium Malloti Apeltae 67g Rhizoma Iridis Japonicae 63g Alumen 62g Spora Lygodii 60g
Folium et Cacumen Salicis Matsudanae 57g Herba senecionis nemorensis 52g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 52g Oletum Trogopterori 47g
Herba Artemisiae Japonicae 43g Cyrtomium fortunei J. Sm. 42g Cortex Phellodendri 37g Radix Hypecol Erecti 34g
Fructus Corni 32g Cycas revoluta Thunb. 29g Carapax Trionycis 24g Fructus Akebiae 19g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Folium Malloti Apeltae 65g Rhizoma Iridis Japonicae 60g Alumen 57g Spora Lygodii 55g
Folium et Cacumen Salicis Matsudanae 52g Herba senecionis nemorensis 48g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 47g Oletum Trogopterori 43g
Herba Artemisiae Japonicae 40g Cyrtomium fortunei J. Sm. 38g Cortex Phellodendri 35g Radix Hypecol Erecti 32g
Fructus Corni 30g Cycas revoluta Thunb. 27g Carapax Trionycis 23g Fructus Akebiae 15g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Folium Malloti Apeltae 62g Rhizoma Iridis Japonicae 57g Alumen 52g Spora Lygodii 50g
Folium et Cacumen Salicis Matsudanae 47g Herba senecionis nemorensis 44g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 42g Oletum Trogopterori 40g
Herba Artemisiae Japonicae 37g Cyrtomium fortunei J. Sm. 35g Cortex Phellodendri 32g Radix Hypecol Erecti 31g
Fructus Corni 27g Cycas revoluta Thunb. 26g Carapax Trionycis 22g Fructus Akebiae 12g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
Folium Malloti Apeltae 57g Rhizoma Iridis Japonicae 52g Alumen 48g Spora Lygodii 47g
Folium et Cacumen Salicis Matsudanae 42g Herba senecionis nemorensis 41g Herba Desmodii Triquetri (Herba Tadehagi Triquetri) 37g Oletum Trogopterori 36g
Herba Artemisiae Japonicae 35g Cyrtomium fortunei J. Sm. 32g Cortex Phellodendri 30g Radix Hypecol Erecti 28g
Fructus Corni 25g Cycas revoluta Thunb. 22g Carapax Trionycis 20g Fructus Akebiae 10g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of hepatitis, select the routine clinical observation of hepatitis 400 of making a definite diagnosis.
Patient is divided into treatment first group and contrast second group two groups at random, treatment first group 200 example, wherein male 99 example, women 101 example, 40 ~ 72 years old age, 53.1 years old mean age, the shortest person of the course of disease 10 months, most elder 22 years, average 10.8 years; Contrast second group 200 example, wherein male 97 example, women 103 example, 41 ~ 70 years old age, 52.5 years old mean age, the shortest person of the course of disease 9 months, most elder 21 years, average 9.8 years.
The course of disease, the degrees of symptoms for the treatment of first group and contrast second group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment first group takes medicine of the present invention, oral 3 times of every day, each 2, warm water delivery service after meal; Within 10 days, be 1 course for the treatment of, usual 2 courses for the treatment of take effect, 3 ~ 4 recoveries from illness course for the treatment of.
Contrast second group injection potassium magnesium aspartate and glucose injection, intravenous drip, a 10 ~ 20ml, adds in 5% glucose injection 250ml or 500ml and slowly instils, every day 1 time, or follows the doctor's advice; Within 40 days, be a course for the treatment of, 2 courses for the treatment of take effect, and the person of being in a bad way is usually invalid.
3, efficacy determination:
(1) cure: hepatitis symptom disappears, and physical recovery is normal on inspection.
(2) effective: the basic or major part of hepatitis symptom disappears, and health recovers substantially on inspection.
(3) effective: hepatitis symptom is clearly better or takes a turn for the better, body part takes a turn for the better on inspection.
(4) invalid: by treating rear hepatitis symptom without being clearly better.
4, result:
Select in the treatment first group of medicine of the present invention, cure 79 examples, effective 73 examples, effective 46 examples, invalid 2 examples, cure rate 39.5%, total effective rate 99%.
31 examples are cured, effective 42 examples, effective 49 examples, invalid 78 examples, cure rate 15.5%, total effective rate 61% in contrast second group.
Above result display, the cure rate for the treatment of first group and total effective rate are apparently higher than contrast second group.
Model case is illustrated:
1, what certain, man, 43 years old, people from Datong, suffered from chronic hepatitis, cured the disease and did not heal for many years, Relapse rate, and time have outbreak, after taking 2 courses for the treatment of of medicine of the present invention, hepatitis is thoroughly cured, and follows up a case by regular visits to, does not recur so far again.
2, Bai, female, 51 years old, people from Baoding, suffer from hepatitis C, cardinal symptom had: detest oil, inappetence, weak, lazy dynamic, low grade fever, and take medicine of the present invention and cure 3 courses for the treatment of, liver function recovery is normal.
3, high certain, man, 60 years old, people from Changchun, Jilin, suffer from acute icterohepatitisshock, the mobility of thrombinogen lower than 40%, serum bilirubin and alaninyl transferring enzyme high, with after 1 course for the treatment of of above-mentioned Drug therapy, the mobility of thrombinogen, serum bilirubin and alaninyl transferring enzyme all recover normal value, no longer recur after healing, follow up a case by regular visits to, do not recur again so far.
4, Cai, female, 71 years old, people from Shenyang, Liaoning, suffering from liver cirrhosis, was unable to leave the bed, and take medicine of the present invention and namely cure 3 courses for the treatment of, liver function recovery is normal.
Claims (5)
1. treat a medicine for hepatitis, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Folium Malloti Apeltae 52 ~ 77 parts of Rhizoma Iridis Japonicaes 47 ~ 72 parts of Alumens 46 ~ 72 parts of Spora Lygodii 42 ~ 67 parts
Folium et Cacumen Salicis Matsudanae 38 ~ 65 parts of Herba senecionis nemorensis 37 ~ 62 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s 34 ~ 57 parts of Oletum Trogopteroris 32 ~ 53 parts
Herba Artemisiae Japonicae 29 ~ 49 parts of Cyrtomium fortunei J. Sm.s 26 ~ 45 portions of Cortex Phellodendris 27 ~ 47 parts of Radix Hypecol Erecti 27 ~ 40 parts
Fructus Corni 22 ~ 37 parts of Cycas revoluta Thunb.s 19 ~ 36 parts of Carapax Trionycis 17 ~ 32 parts of Fructus Akebiaes 7 ~ 27 parts.
2. a kind of medicine for the treatment of hepatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Folium Malloti Apeltae 57 ~ 72 parts of Rhizoma Iridis Japonicaes 52 ~ 69 parts of Alumens 48 ~ 67 parts of Spora Lygodii 47 ~ 64 parts
Folium et Cacumen Salicis Matsudanae 42 ~ 62 parts of Herba senecionis nemorensis 41 ~ 57 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s 37 ~ 54 parts of Oletum Trogopteroris 36 ~ 50 parts
Herba Artemisiae Japonicae 35 ~ 47 parts of Cyrtomium fortunei J. Sm.s 32 ~ 44 portions of Cortex Phellodendris 30 ~ 42 parts of Radix Hypecol Erecti 28 ~ 37 parts
Fructus Corni 25 ~ 34 parts of Cycas revoluta Thunb.s 22 ~ 32 parts of Carapax Trionycis 20 ~ 27 parts of Fructus Akebiaes 10 ~ 24 parts.
3. a kind of medicine for the treatment of hepatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Folium Malloti Apeltae 62 ~ 67 parts of Rhizoma Iridis Japonicaes 57 ~ 63 parts of Alumens 52 ~ 62 parts of Spora Lygodii 50 ~ 60 parts
Folium et Cacumen Salicis Matsudanae 47 ~ 57 parts of Herba senecionis nemorensis 44 ~ 52 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s 42 ~ 52 parts of Oletum Trogopteroris 40 ~ 47 parts
Herba Artemisiae Japonicae 37 ~ 43 parts of Cyrtomium fortunei J. Sm.s 35 ~ 42 portions of Cortex Phellodendris 32 ~ 37 parts of Radix Hypecol Erecti 31 ~ 34 parts
Fructus Corni 27 ~ 32 parts of Cycas revoluta Thunb.s 26 ~ 29 parts of Carapax Trionycis 22 ~ 24 parts of Fructus Akebiaes 12 ~ 19 parts.
4. a kind of medicine for the treatment of hepatitis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Folium Malloti Apeltae 65 parts of Rhizoma Iridis Japonicaes 60 parts of Alumens 57 parts of Spora Lygodii 55 parts
Folium et Cacumen Salicis Matsudanae 52 parts of Herba senecionis nemorensis 48 portions of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s 47 parts of Oletum Trogopteroris 43 parts
Herba Artemisiae Japonicae 40 parts of Cyrtomium fortunei J. Sm.s 38 portions of Cortex Phellodendris 35 parts of Radix Hypecol Erecti 32 parts
Fructus Corni 30 parts of Cycas revoluta Thunb.s 27 parts of Carapax Trionycis 23 parts of Fructus Akebiaes 15 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the medicine of hepatitis, it is characterized in that: comprise following processing step:
(1) Alumen, Radix Hypecol Erecti, Fructus Corni and Cycas revoluta Thunb. are mixed, carry out pulverization process after mix homogeneously, grind into powder, cross 120 order fine powders, for subsequent use;
(2) Rhizoma Iridis Japonicae, Spora Lygodii, Folium et Cacumen Salicis Matsudanae, Herba senecionis nemorensis, Herba Artemisiae Japonicae, Cyrtomium fortunei J. Sm., Cortex Phellodendri and Fructus Akebiae are cleaned, put into container, add the distilled water of 8 ~ 12 times amount, soak after 4 ~ 5 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 50 DEG C is the thick paste of 1.10 ~ 1.14, for subsequent use;
(3) cleaned by Folium Malloti Apeltae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Oletum Trogopterori is put micro-stir-fry in pot, sprays rice vinegar, then fry to micro-dry, surface slightly gloss time take out, dry, grind into powder, cross 200 order fine powders, for subsequent use;
(5) cleaned by Herba Desmodii Triquetri (Herba Tadehagi Triquetri), immerse the alcohol solution dipping 1 ~ 2 hour of 85% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, under filtrate simmer down to 60 DEG C of environment, the thick paste of relative density 1.20 ~ 1.25, for subsequent use;
(6) sandy soil put in pot heat, loosen to sandy soil, get Carapax Trionycis and put into pot and fry to the micro-yellow of epidermis, take out sieve and remove sandy soil, put into vinegar basin and slightly soak, every 100 jin with vinegar 30 jin, taking-up is dried, and grinds into powder, mistake 160 order fine powders, for subsequent use;
(7) made for above-mentioned steps (1) ~ (6) fine powder, thick paste and juice are mixed, add adjuvant, make capsule, obtain the medicine of described treatment hepatitis.
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| CN106924321A (en) * | 2015-12-30 | 2017-07-07 | 姚萍 | Application of the Artemisia japonica in the medicine for preparing treatment virus B hepatitis |
| CN105920380A (en) * | 2016-04-13 | 2016-09-07 | 林家希 | Repair traditional Chinese medicine used for treating blood cell infected by flaviviridae |
| CN115212253B (en) * | 2022-08-05 | 2023-04-11 | 南京中医药大学 | Chinese herbal compound preparation for treating hepatic fibrosis and preparation method and application thereof |
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