CN103300363B - Anti-fatigue traditional Chinese medicine capsule and preparation method thereof - Google Patents
Anti-fatigue traditional Chinese medicine capsule and preparation method thereof Download PDFInfo
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- CN103300363B CN103300363B CN201310205708.6A CN201310205708A CN103300363B CN 103300363 B CN103300363 B CN 103300363B CN 201310205708 A CN201310205708 A CN 201310205708A CN 103300363 B CN103300363 B CN 103300363B
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Abstract
The invention provides an anti-fatigue traditional Chinese medicine capsule which comprises the following components in parts by weight: 27-33 parts of a herba epimedii extract, 30-40 parts of dietary fiber, 27-33 parts of an Eucommia ulmoides extract, 1-4 parts of an American ginseng extract, 30-40 parts of a grape seed extract, appropriate parts of an auxiliary material gelatin, and further 10 parts of vitamin C. The anti-fatigue traditional Chinese medicine capsule provided by the invention has the functions of tonifying yang of liver and kidney, strengthening the bones and muscles, expelling wind-damp, adjusting the digestive system, adjusting blood balance, tonifying qi and yang, preventing fatigue and resisting oxidation. The capsule tested can remarkably improve the sexual function of males and improve the quality of sexual life.
Description
Technical field:
The present invention relates to Chinese medicine preparation technical field, be specially traditional Chinese medicine health capsule of a kind of antifatigue and preparation method thereof
Background technology:
The survey report providing according to property expert, the sexual life of appropriateness can make the male sex's testosterone secretion amount increase, and the effect of testosterone can make the muscular of the male sex, improves the hematopoietic potential of marrow.For women, if can obtain fully satisfied in the sexual life of being everlasting, the physiological function of ovary and endocrine ability will strengthen, its skin will become more soft and smooth and it is glossy, it is more glossy that hair can become, it is more optimistic that spirit can become, so there be word saying so: the sexual life of rule is best in the world beautician.American scientist confirms after deliberation, can be often and the sexual life that is satisfied with of spouse, and man suffers from the possibility that prostate cancer, woman suffer from breast cancer will be much smaller.Suitable sexual life also has a benefit to enhance metabolism exactly, prevents early ageing, prevents brain aging.According to the investigation to long-lived population, all long-lived persons often have and the sexuality of rule.Can determine thus, sexual life and the longevity of appropriateness have certain positive connection.Sexual life can also be confirmed from the negative to the benefit of health, according to from scientific research personnel, divorce, unmarried woman and compare wedding person, suffer from the cancer of the uterus the death rate the former be the latter 2-3 doubly.Aspect deaths from heart disease rate, divorcee is also apparently higher than the married.
In other words, the sexual life of rule does not have any difference to the benefit of health and physical training, has a lot of Physical Trainings to be beneficial to health, and psychology is not but had to direct effect.And sexual life has unique advantage in this respect.Can enjoy the joyful people of sexual life and be not easy to be subject to lonely and lonely torment, compare with celibate, it is much lower that trouble is not controlled the ratio of not disease, mental disease, suicide.Because the former does not have sense of depression psychologically, its aging course is also much slow than the latter.
In the U.S. reproductive medicine association annual meeting of holding recently, brainstrust has been delivered an investigation result about male sex's sexual desire.Result shows, because the large rhythm of life of modern life pressure is fast, just feels more tired, unable to do what one wishes people in middle age, is the problem that generally makes male sex's worry, and can affects the marital relations of most people.So some men start to take vigour medicine, vigour has shortterm effect after having eaten, but has side effects, infringement health.
Food and nutrient promote sexual desire, modulability impression and enhancing sexual function, become the direction of people's research.
Summary of the invention:
The technical problem to be solved in the present invention is to provide a kind of traditional Chinese medicine health capsule of antifatigue, in order to submit quality of life to, and the preparation method of this traditional Chinese medicine health capsule.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A traditional Chinese medicine health capsule for antifatigue, comprises following weight component: barrenwort 27-33 part extract, dietary fiber 30-40 part, bark of eucommia 27-33 part extract, American Ginseng 1-4 part extract, grape pip 30-40 part, auxiliary material gelatin are appropriate.
Described composition by weight also comprises 10 parts of vitamin Cs.
As preferably, comprise following weight component: 30 parts of extracts of barrenwort, 35 parts of dietary fibers, 30 parts of extracts of the bark of eucommia, 1.5 parts of extracts of American Ginseng, 35 parts of grape pips, 2 parts, auxiliary material gelatin.
The preparation method of the traditional Chinese medicine health capsule of a kind of antifatigue of the present invention, is characterized in that: comprise the steps:
One, barrenwort, the bark of eucommia, American Ginseng supercritical carbon dioxide extracting extract three times, and each 2 hours, reclaim carbon dioxide, filtrate is concentrated into the thick paste that 70 ℃ of condition relative densities are 1.1～1.2;
Two, grape pip is pulverized rear supercritical carbon dioxide extracting extraction three times, and each 2 hours, reclaim carbon dioxide, filtrate is concentrated into the thick paste that 70 ℃ of condition relative densities are 1.1～1.2;
Three, the thick paste of step 1 and step 2 is dry respectively, 100 orders are pulverized, and sieve, and obtain dry thing;
Four, dietary fiber 100 orders are pulverized, and sieve;
Five, will be dried thing and dietary fiber, vitamin C, and obtain active constituents of medicine, this active component is directly made gelatine capsule or is mixed and made into capsule with medicine acceptable carrier.
In the present invention, in carbon dioxide abstraction leaching process, extraction temperature is controlled at 35 ℃, and pressure is controlled at 8 MPas.
Barrenwort
Kidney-replenishing, strengthening the bones and muscles, wines used as antirheumatic.For impotence and seminal emission, muscles and bones impotence is soft, arthralgia due to wind-dampness, numbness contracture; Climacteric hypertension.
, cold extremities with aversion to cold soft for impotence due to deficiency of the kidney, seminal emission premature ejaculation, waist knee impotence.Control impotence something lost and let out, can join the product such as thizoma curculiginis, dogwood fruit, saline cistanche; Control waist knee impotence soft, can join the product such as the bark of eucommia, Morinda officinalis, rhizoma cibotii.Numb for numbness and ache of cold dampness or spasm of limbs.Controls arthralgia due to wind-dampness and be partial to cold-dampness person, and numb limb is meciless or muscles and bones contraction etc., can with the compatibilities such as the root of Chinese clematis, Morinda officinalis, Chinese cassia tree, Radix Angelicae Sinensis, Ligusticum wallichii.
Barrenwort is the cauline leaf of the multiple barrenwort such as Berberidaceae plant barrenwort, arrow leaf barrenwort, Wushan barrenwort, korean epimedium herb.Barrenwort perennial herb, summer, autumn gather, and extract cauline leaf, remove impurity, dry.
Barrenwort aerial part is long 20 to 40 centimetres, stem thin rod shape, rib smoothly or slightly, tool gloss.Two times trifoliolate leaves; Tool long handle; Vanelets oval, long 3 to 7 centimetres, wide 2 to 5 centimetres, edge tool thorn-like serration; Upper surface green or yellow green, slightly glossy, without hair, lower surface celadon, has pubescence along vein, and arteries and veins base is longer.The nearly keratin of blade is more crisp.Gas is micro-, mildly bitter flavor.
Long 25 to 45 centimetres of the lascivious sheep leaves of pulse plants of arrow leaf aerial part, a trifoliolate leaf, long 4 to 10 centimetres of leaflet, the hard thorn-like of leaf edge sawtooth, is about 2 millimeters, following table mask open wool or near without hair.Blade keratin is firmly crisp.
Long 40 to 70 centimetres of Wushan barrenwort aerial part, a trifoliolate leaf, vanelets lanceolar, wide 2 to 4 centimetres, be about 5 times into this.
Korean epimedium herb aerial part is about 35 centimetres.Two times trifoliolate leaves, commodity mostly are monolithic leaflet, vanelets width egg shape, edge sawtooth is furry, blade film matter.
All take, colour band green person many without rhizome, blade as good.
Barrenwort trophic analysis:
HERBA EPIMEDII mainly contains icariine etc., and HERBA EPIMEDII extract has the effect of male sex hormone sample, can promote gonopoiesis, hypoglycemic; Be improved hypophysis--the effect of interrenal system function, and can form by enhancing antibody.
According to the difference of concocting method, be divided into barrenwort and barrenwort processed.Barrenwort gets crude drug, removes impurity and branch stalk, gets leaf, cleans, slightly moisten, and chopping, dry.Barrenwort processed is divided into again suet system, butter system, wine system, frying.
In medicinal material storage drying receptacle after the process of preparing Chinese medicine, airtight, put shady and cool dry place, protection against the tide.
Barrenwort is applicable to crowd:
1. cold infertile, the deficiency of yang hypertension of suitable impotence, palace, climacteric disease crowd.
Fire excess from yin deficiency penis ultroerection easily act person prohibit clothes.
Barrenwort dietary function:
Barrenwort taste is pungent, sweet, warm in nature; Return Liver Channel; The light gas of body is male, can rise and can fall
Cure mainly impotence, seminal emission premature ejaculation, cold sperm is sterile, frequent micturition incontinence, dyspnea and cough due to deficiency of the kidney, soreness and weakness of waist and knees, muscles and bones contraction is anxious, arthralgia due to wind-dampness, hemiplegia, four limbs are meciless.
The bark of eucommia
The bark of eucommia is the dry bark of the Eucommiaceae plant bark of eucommia (Eucommia ulmoides Oliver), is Chinese famous and precious tonic herb.Tool filling liver kidney, strengthening the bones and muscles, many effects such as hypotensive, antiabortive.< < Sheng Nong's herbal classic > > classifies as top grade.Call its " cure mainly waist and knee, bowl spares, beneficial vital essence, hard muscles and bones, wet except itching under the moon, dribbling urination.Clothes, make light of one's life by commiting suicide resistance to old for a long time." bark of eucommia is Chinese peculiar medicinal material, its medicinal history is long, clinical, has a wide range of applications.Oneself finds nearly 14 kinds of bark of eucommia platymisciums on earth so far, and they became extinct in succession in continent and Europe afterwards.Being present in the Chinese bark of eucommia is that the Eucommiaceae bark of eucommia belongs to the Relict Plant of only depositing, and it not only has very high economic worth, and all has very important scientific value for all many-sides such as origin of research angiosperm phylogeny and Chinese Flora.It is existing that oneself is put into < < Chinese Plants Red Data Book-rare endangered plants > > first volume as rare plant.
Both at home and abroad expert has carried out repeatedly careful research to bark of eucommia composition, and bark of eucommia free amino acid is few, a small amount of protein containing, be with most foodstuffs like adequate proteins, can be hydrolyzed 8 seed amino acids that detect needed by human.Measure 15 kinds of contained mineral elements of the bark of eucommia, wherein had the trace elements such as zinc, copper, iron, and the macroelement such as calcium, phosphorus, potassium, magnesium.
The bark of eucommia has filling liver kidney, and rubbish in body is removed in strengthening the bones and muscles, strengthen human body cell metabolism, prevent that muscle skeleton is aging, balance human blood-pressure, decomposer inner cholesterol, reduce body fat, recover blood vessel elasticity, diuresis heat-clearing, broad-spectrum antiseptic, stimulating central nervous system, improves white blood cell count, strengthens the remarkable efficacy such as body immunity.
American Ginseng
American Ginseng in the traditional Chinese medical science has following feature:
[meridian distribution of property and flavor] sweet, micro-hardship, cool.The thoughts of returning home, lung, kidney channel.
[function cures mainly] boosting qi and nourishing yin, clearing heat and promoting fluid.For the deficiency of vital energy is cloudy, lose, interior heat, coughs and breathes heavily phlegm blood, and abnormal heat is tired tired, quench one's thirst, and dryness of the mouth and throat.American Ginseng has antifatigue, anti-oxidant, the anti-effect that stress, suppress platelet aggregation, reduces blood clotting, in addition, diabetic is regulated in addition to the effect of blood sugar.
[chemical composition] rhizome is containing Chikusetsusaponin V, Rb1, Rb2, Rc, Rd, Re, Rg1 and panicled fameflower root saponin F11(pseudoginsenosideF11), still containing 18 seed amino acids such as arginine, aspartic acids; Again containing volatile oil, resin etc.
[pharmacological action] zoopery, has sedation to brain, vital center is had to the excitation of moderate.
Grape pip
Through high-tech approach, extract its effective ingredient (former blue and white plain oligomer, english abbreviation OPC) and be aided with that vitamin C is refining to be formed.Grape seed extract (OPC) is a kind of efficient free radical scavenger.Can remove poisonous free radical in human body, protection human cell tissue exempts from, by the oxidative damage of free radical, to prevent the diseases relevant with free radical of kind more than 80 such as allergy, cancer, aging.Vitamin C can reduce fragility and the permeability of capillary, corrects irritated pathological change, is simultaneously also radicals scavenging and antioxidant, coordinates grape seed extract (OPC), to correcting allergy, physique texts is more remarkable.The common anaphylactia of the mankind comprises bronchial astehma.Due to human normal metabolic processes, smoking, edible fat and salting down fire-cure meat, be inflamed, some cancer therapy drug, hypnotic, computer radiate, agricultural chemicals, organic matter rot, the ozone in air pollution, chemical carcinogen, atmosphere etc. also can produce free radical.If free radical can not be got rid of in time, easily cause the diseases relevant with free radical of kind more than 80 such as allergy, cancer, aging.As: headache, dizzy, decrease of platelet, hypoimmunity, arthritis, cataract, the retinitis, headstroke, person of a serious nature may cause cancer.Grape pip anti-ageing, antioxidant effect is very good, it be vitamin C and vitamin E 30-50 doubly.
Dietary fiber
Dietary fiber is the mixture that comprises the Multiple components such as cellulose, hemicellulose, lignin, pectin and soluble polysaccharide.Dietary fiber has multiple physiological hygiene function, closely related with health, lacks dietary fiber and can cause various diseases, so extremely consumer's favor of the goods that contain dietary fiber.Edible fiber products dietary fiber is extensively present in fruit, vegetables, cereal, beans and other water plant.By the research that deepens continuously to dietary fiber, its various physiological hygiene functions are also constantly excavated.China Shi Ge large agricultural country, and dietary fiber is extensively present in plant.
1, the definition of dietary fiber and composition
The mixture that dietary fiber is comprised of Various Complex organic substance but not single entities, have suitable intestines defaecation, regulate one or more physiological functions such as controlling blood sugar concentration, reducing blood lipid.Dietary fiber is a kind of edible vegetalitas composition, but not animal component.Dietary fiber wide material sources, are present in the materials such as vegetables, fruit, coarse food grain, coarse cereals, agar, pectin.
2, dietary fiber and health
2.1 promote colon function, prevent colon cancer
Nineteen sixty South Africa scholar Oettle has found contacting of dietary fiber and human cancer first, has after this carried out again large quantity research and test, and result thinks that high fiber, low-fat diet can reduce the incidence of colon cancer.Colon cancer may cause as effects such as nitrosamine and phenol, ammonia due to certain stimulus or poisonous substance.These Toxics stop long in colon, will be to intestines wall generation toxic action.Research shows, because dietary fiber water imbibition is strong, has relatively increased the volume and weight of ight soil, has diluted carcinogen concentrations in intestines, thereby plays the effect of anti-cancer; Secondly, dietary fiber accelerates the emptying of intestinal contents, has reduced the generation of microorganism in intestines or has changed carcinogenic chance, has shortened the action time that carcinogenic substance contacts with intestines wall, therefore can reduce the incidence of colon cancer.
2.2 treatment diabetes
Diabetes are a kind of whole body chronic metabolic disease that determined by inherent cause, because insulin in body is relative or absolute deficiency causes that carbohydrate, fat and protein metabolism are disorderly, are characterized in hyperglycaemia and glycosuria.Recently research shows, food fiber has and falls hypoglycemic effect, and wherein water-soluble fibre effect is larger, as bean gum, pectin, mushroom taro polysaccharide etc.Hypoglycemic mechanism of action can fall in pectin: pectin absorbs moisture, forms gel filtration system in enteron aisle, changes nutrient and comprises digesting and assimilating of monose and disaccharides; Pectin can reduce the secretion of gastrointestinal hormone " gastric inhibitory potypeptide ", and glucose absorption rate is reduced.Therefore, eat the health that rich pectous fruit is of value to diabetes patient's health more.
2.3 prevent coronary heart disease
By daily meals adjustment, can control coronary heart disease, especially the water-soluble dietary fiber more remarkable effect that raises and cause due to blood cholesterol levels.This is because dietary fiber has the effect of absorption cholesterol on the one hand, makes cholesterol be difficult for seeing through intestinal mucosa and absorbs; On the other hand, dietary fiber can partly be blocked the intestines liver circulation of bile acid and cholesterol, accelerates cholate, cholic acid etc. from defecate, thereby reduces cholic acid and cholesterol levels in blood, plays the effect that prevents and treats coronary heart disease.
2.4 detoxication
The mechanism of action of dietary fiber removing toxic substances is: 1. promotes gastrointestinal motility, and in colon, plays stronger osmosis, thus the concentration of having diluted the medicine in gastrointestinal contents, food additives and harmful chemical; 2. shorten intestinal contents by the time of enteron aisle, reduce colon internal pressure, shorten the solution time that connects of enteral prods and intestines wall; 3. noxious material is wrapped up; 4. with the combination of metal cation, the illeffects of antagonism chemicals and food additives.By these mechanism, delay directly or indirectly, reduce digesting and assimilating of external harmful substance, play the hypotoxic effect of falling.
2.5 antiobesity actions. dietary fiber enters after stomach and intestine, because it can absorb moisture, makes volumetric expansion, increases satiety, reduces food-intake, thereby reaches the object of fat-reducing.
In a word, dietary fiber is inseparable with health, and dietary fiber intake deficiency can cause the generation of various diseases.China to dietary fiber research relatively a little later, more because propaganda strength is inadequate, its health care is also rarely known by the people.China is populous, and along with the growth of various rich man's disease populations, believes that dietary fiber enhanced products necessarily has more vast potential for future development.
The pharmaceutical compositions of compatibility of the present invention, has following good effect through checking:
Tonifying liver kidney yang, strengthening the bones and muscles, wines used as antirheumatic, regulate digestive system, regulate blood balance, boosting qi and nourishing yin, antifatigue, anti-oxidant, through test, can obviously improve male's sexual, improve life quality.
Embodiment specifically:
The traditional Chinese medicine health capsule of a kind of antifatigue provided by the present invention, comprises following weight component: 30 parts of extracts of barrenwort, 35 parts of dietary fibers, 30 parts of extracts of the bark of eucommia, 1.5 parts of extracts of American Ginseng, 2 parts, 35 parts, 10 parts vitamin Cs of grape pip, auxiliary material gelatin.
The preparation method of the traditional Chinese medicine health capsule of a kind of antifatigue of the present invention, is characterized in that: comprise the steps:
One, barrenwort, the bark of eucommia, American Ginseng supercritical carbon dioxide extracting extract three times, and each 2 hours, reclaim carbon dioxide, filtrate is concentrated into the thick paste that 70 ℃ of condition relative densities are 1.1～1.2;
Two, grape pip is pulverized rear supercritical carbon dioxide extracting extraction three times, and each 2 hours, reclaim carbon dioxide, filtrate is concentrated into the thick paste that 70 ℃ of condition relative densities are 1.1～1.2;
Three, the thick paste of step 1 and step 2 is dry respectively, 100 orders are pulverized, and sieve, and obtain dry thing;
Four, dietary fiber 100 orders are pulverized, and sieve;
Five, will be dried thing and dietary fiber, vitamin C, and obtain active constituents of medicine, this active component is directly made gelatine capsule or is mixed and made into capsule with medicine acceptable carrier.
In the present invention, in carbon dioxide abstraction leaching process, extraction temperature is controlled at 35 ℃, and pressure is controlled at 8 MPas.
The foregoing is only embodiments of the invention, be not limited to patent of invention, for a person skilled in the art, the present invention can have various modifications and variations.All within the spirit and principle of invention, any modification of doing, be equal to replacement, improvement etc., within all should being included in the claim scope of invention.
Claims (4)
1. a preparation method for the traditional Chinese medicine health capsule of antifatigue, is characterized in that: comprise the steps:
One, composition by weight barrenwort 27-33 part, bark of eucommia 27-33 part, American Ginseng 1-4 part supercritical carbon dioxide extracting extract three times, and each 2 hours, reclaim carbon dioxide, filtrate is concentrated into the thick paste that 70 ℃ of condition relative densities are 1.1～1.2;
Two, composition by weight grape pip 30-40 part is pulverized rear supercritical carbon dioxide extracting extraction three times, and each 2 hours, reclaim carbon dioxide, filtrate is concentrated into the thick paste that 70 ℃ of condition relative densities are 1.1～1.2;
Three, the thick paste of step 1 and step 2 is dry respectively, 100 orders are pulverized, and sieve, and obtain dry thing;
Four, composition by weight dietary fiber 30-40 part 100 orders are pulverized, and sieve;
Five, will be dried 10 parts of thing and dietary fiber, vitamin Cs and mix, and obtain active constituents of medicine, this active component is directly made gelatine capsule.
2. a kind of preparation method of traditional Chinese medicine health capsule of antifatigue according to claim 1, is characterized in that: in carbon dioxide abstraction leaching process, extraction temperature is controlled at 35 ℃, and pressure is controlled at 8 MPas.
3. the preparation method of the traditional Chinese medicine health capsule of a kind of antifatigue according to claim 1 and 2, is characterized in that: 30 parts of described composition by weight barrenwort, 30 parts of the barks of eucommia, 35 parts of dietary fibers, 1.5 parts of American Ginsengs, 35 parts of grape pips, 2 parts, gelatin.
4. a traditional Chinese medicine health capsule for antifatigue, is characterized in that: adopt the method for claim 1 or 2 to make.
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| CN100490864C (en) * | 2006-06-16 | 2009-05-27 | 湖北阳光医药科技有限公司 | Yin-nourishing fatigue-relieving capsules |
| CN101513437B (en) * | 2008-02-21 | 2011-12-07 | 中国科学院上海药物研究所 | Antifatigue Chinese pharmaceutical composition and preparation method thereof |
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