CN103271938A - Medicine formula for curing burns, scalds and wounds - Google Patents

Abstract

The invention provides a medicine formula for curing burns, scalds and wounds. The formula is prepared from the following traditional Chinese medicine components in part by weight: 10-14 parts of vegetable oil, 1-5 parts of borneol and 1-3 parts of alum powder. The medicine formula is suitable for the preparation of various tablets, capsules, powder, pills and sirup and has the characteristics of instant effect and good curative effect.

Description

A kind of medicament composing prescription for the treatment of burn, scalding and wound

Technical field

The present invention relates to a kind of Chinese prescription, this prescription has the function of anti-inflammation, removing the necrotic tissue and promoting granulation, reducing swelling and alleviating pain, convergence dampness, has therapeutical effect preferably for burning, scalding and wound.

Background technology

The occurrence frequency of contingency such as burn, scald, wound is very high, and often wound surface is big, and wound is dark, and wound is easy to infection suppurates, can cause systemic inflammatory responses as untimely treatment, brings serious actual bodily harm to the patient.

The western medicine burn and scald is divided into medicine (sulfa drugs) based on infection and the medicine (heparin, insulin, zinc preparation and various somatomedin etc.) of promoting healing, chemicals has a broad antifungal spectrum and be easy to produce drug resistance.

Motherland's medical science is of long standing and well established, accumulated the Chinese prescription that some treatments are burnt, scalded, wound, such as holding back a mouthful granulation promoting medicine Margarita powder (water soluble Margarita ultrafine powder), blood activating and promoting tissue regeneration medicine Olibanum (Olibanum water extract), warming YANG granulation promoting medicine Cornu Cervi Pantotrichum (antler polypeptide), all can reach the purpose for the treatment of wound by promoting human dermal fibroblast cell propagation and collagen synthetic.Weak point is that prescription is complicated, and raw material is difficult to obtain.

Chinese prescription of the present invention through studying traditional Chinese medical science ancient books for many years, is made up of conventional Chinese medicine material simple formulation, and again through clinical excess syndrome for many years, the accumulation clinical case is countless, confirms that this prescription has the good curing effect for burning, scald, wound etc.

Technology contents

Purpose of the present invention provides a kind of and treats burn, scalds and wound Chinese prescription, and this prescription has the function of anti-inflammation, removing the necrotic tissue and promoting granulation, reducing swelling and alleviating pain, convergence dampness, can effectively treat burning, scald, wound.

Treatment of the present invention burn, scald and wound Chinese prescription and formed by following preparation of raw material: Borneolum Syntheticum, alum powder, vegetable oil.

Treatment of the present invention is burnt, is scalded and wound Chinese prescription, and the weight portion proportioning of each composition is:

10～40 parts of vegetable oil, 1～5 part of Borneolum Syntheticum, 1～3 part of alum powder.

Treatment of the present invention is burnt, is scalded and wound Chinese prescription, and the weight portion proportioning commonly used of each composition is:

20 parts of vegetable oil, 1 part of Borneolum Syntheticum, 1 part of alum powder.

Medicament composing prescription of the present invention, its method for preparing be, vegetable oil is heated to about 120～150 degree, adds alum powder, Borneolum Syntheticum, stirs, and fusion boiled 30 minutes, cooling, bottling sealing.In the wound surface smearing external.

In the process that medicinal liquid of the present invention, treatment are burnt, scalded and wound, pay special attention to dietetic contraindication and wound surface and handle:

1. protect epidermis, if any blister, just puncture with sterile needle and discharge water;

2. absolute fasting Fructus Cucurbitae moschatae, eggs and Semen Glycines group food;

3. forbid to mix with other drug and use or be used alternatingly, avoid having side effects;

4. absolute prohibition cleans wound surface with saline;

5. accomplish not wrap up as far as possible, make every effort to expose treatment;

6. for preventing extremely indivedual medication discomforts, can do the small size experiment, if any discomfort, available Ovum Gallus domesticus album, Borneolum Syntheticum water clean.

The pharmacological basis of used each Chinese medicine of the present invention is:

Borneolum Syntheticum, acrid in the mouth, cold in nature, logical all keys, diffusing stagnated fire are arranged, effects such as detumescence removing nebula.Traditional medicine thinks, but Borneolum Syntheticum removing the necrotic tissue and promoting granulation, reducing swelling and alleviating pain, and so be used for aphtha, carbuncle, that modern medicine experiment confirm, Borneolum Syntheticum have is antibiotic more, antiinflammatory, analgesic effect, identical of views with traditional medicine.

1, antibacterial action: Borneolum Syntheticum can suppress or kill clinical common bacterias such as staphylococcus aureus, beta hemolytic streptococcus, viridans streptococci, MIC and MBC are respectively 1.0%～1.5% and 1.5%～2.0%, main component Borneolum Syntheticum wherein is all consistent with Borneolum Syntheticum with the effect of isoborneol, does not also have collaborative but both there be not antagonism between two components.Borneolum Syntheticum also has antibacterial action to 5 kinds of common funguses such as red mentagrophytes, and its action principle and Borneolum Syntheticum easily see through cell wall, cause cell membrane damage, destroys and changes that it is permeability-related.

2, antiinflammatory action: the main component Borneolum Syntheticum in the Borneolum Syntheticum and isoborneol all can suppress due to the Ovum Gallus domesticus album rat foot and open up swelling, and they have inhibitory action to oozing out with the inflammation process that swells such as tissue edema of liquid.Its principle may discharge relevant with antagonism PGE and inflammation-inhibiting medium.

3, analgesic effect: after the laser burn wound surface directly used Borneolum Syntheticum, animal model pain fault value was higher 2.78 times and 6.24 times respectively than JINGWANHONG group (positive control) and normal saline group (negative control).The compound preparation that use contains Borneolum Syntheticum is treated clinical various pain report also the time.

Borneolum Syntheticum is conventional Chinese medicine material simply, and adapted is all arranged in various prescriptions, such as Borneolum Syntheticum compatibility Cortex Phellodendri: the Borneolum Syntheticum toil is cool in nature be longer than logical all keys, the stagnated fire of loosing, removing nebula make eye bright external can clearing heat for detumescence, antipruritic pain relieving; Cortex Phellodendri bitter cold merit is arrogated to oneself heat clearing and damp drying, eliminating fire and detoxication.External can eliminating dampness and astringing sores.The two mutually 5 externals the effect of clearing away heat-fire, removing toxic substances and promoting subsidence of swelling, eliminating dampness and astringing sores, antalgesic-antipruritic is arranged, be used for the treatment of and attack diseases such as caused oral erosion, ulcer, aphtha of the mouth and tongue, laryngopharynx swelling and pain on strongly fragrant in burning hot.

Except Borneolum Syntheticum itself has expelling pus and promoting granulation, anti-inflammation pain-relieving functions, prescription of the present invention adopts Borneolum Syntheticum to also have important consideration to be exactly, and Borneolum Syntheticum can effectively improve bioavailability, impels the medicine bulk concentration to raise, particularly for external preparation, can effectively improve the ability of other drug Transdermal absorption.The related article that shakes Lu people such as space, Lin Xingyao deliver in " traditional Chinese medical science medical science newspaper " 2002 the 30th the 3rd phase of volume is seen in this effect.

Alum powder, cold in nature, sour in the mouth, puckery.Go into lung, liver, spleen, stomach, large intestine channel.The effect that Bearberry Extract dampness, detoxifcation parasite killing, dampness removing to stop itchin, hemostasis antidiarrheal, detoxifcation are eliminated the phlegm.

Treatment burn of the present invention, the Chinese prescription of scalding and wound have instant effect, eutherapeutic characteristics.

Main reference document: [1] Zhou Xiaoya. the pharmacological research of Chinese medicine Borneolum Syntheticum [J]. contemporary Chinese is used pharmaceutical journal, 1986,15 (3): 17; [2] Ruan Liangui. Borneolum Syntheticum ethanol bandaging method for treating I, II degree burn [J]. practical combination of Chinese and Western medicine magazine, 1992,5 (2): 102; [3] shake space, Lin Xingyao of Lu. Borneolum Syntheticum improves bioavailability study overview [J]. Chinese medicine journal, 2002,3 (3): 67; [4] Liu Xiangjun. the progress of burn wound's medicine for external use [J]. China and foreign countries' medical research, 2011,9 (11): 118; [5] Liu Yang, Zhang Baili, Hu Limin. the pharmacological experiment study overview [J] of Borneolum Syntheticum. Tianjin Chinese medicine, 2003,20 (4): 85; [6] Li Zhi, Li Huaibao etc. compound giant knotweed burn liquid and burn oil treatment burn 38 examples [J]. the Shaanxi traditional Chinese medical science, 2004,25 (6): 515.

Clinical efficacy

1, sample information

The patient all is because burns such as scald such as boiled water, gruel, oil, the soup of cooking meat and gasoline, coal gas, molten steel, flash burn, and gas cylinder, firecrackers etc. be wound etc.

2, Therapeutic Method

At first will need make simple debridement treatment to hindering face, cut off blister and slough, crust or eschar needn't be gone excision firmly, treat that medicine dissolves it.Spread on burn wound with set burn oil gauze then.It is more to wrap up early stage wound fluid, and day changes dressings 1～2 time, what oozes out with backsight, and 2～3d changes dressings 1 time, can change dressings in 1 week 1 time after the improvement.

3, therapeutic effect

The history in existing more than 30 year of patient of using medicinal liquid treatment of the present invention to burn, scald, wound has been cured thousands of routine patients, and total cure rate reaches more than 97%, more the no cicatrix in back.Wherein wound area reaches the patient more than 50%, has rescued the spadger's of 2 discontented 2 one full year of life immature life, the not enough 1000g that dosage is maximum, and the longest more than 10 day of time, the shortest 4 hours, and only smear medicine one time.Carried out cutting the crust skin-grafting except 2 examples, other are all cured with this Chinese prescription merely.

4, model case

Classes are over 19, afternoon for (1) 1978 on JIUYUE, and daughter's light foot fault of 4 years old of Zhong Qiling is stepped on and burnt red electric welding flatiron, and sole is smoldered, and pain is wailed, and I spread by the medication oil that loses no time, and after 30 minutes, child just can go out to play.Medication was once just got well, and has not been had scar in second day entirely.

On July 24th, (2) 1984,2 years old boy Lin Aihong in village under the Gu Cunda room, Yang Qiao town, Fenyi County, Jiangxi Province falls in the boiling water that mother just poured foot washing basin into because of carelessness, and face, neck, breast, abdomen and extremity are rats after severe scald burn all, and exfoliation is more than body temperature 40 degree, so tragic that one cannot bear to look at it.After seek medical advice to me upon somebody's introduction, I to he spread medicinal liquid after about 20 minutes child slowly sleeping.Serious because scalding, the head of a family is worried, still embraces into Fenyi County's hospitalize more than 10 day.24 hours every days, hanging point dripped, and wound dressing gets tight.The result whenever changes a medicine child and just cries dusk once, and body temperature is high always, hot summer, and the wound surface severe infections suppurates, and death is expected at any moment.Leave hospital by force after the head of a family realizes the truth and seek medical advice to me again, I only just cure fully with the medicinal liquid treatment of not enough 500g, do not stay any scar.

In afternoon on July 5th, (3) 1985, Li Xiang wealth two is held the pig feed that a big iron pan burns bubble in hands, because of pot not only heavily but also hot, because of carelessness whole pot of pig feed fallen down from chest.I smear to him with medicinal liquid at once.Timely because of medication, only smeared once, disappear entirely with regard to burning pain after 4 hours, the scalding area of whole body more than 50%, competing a little redness does not all have.

In the tenth day of lunar month morning in first month of the lunar year, (4) 1984, the firecracker that Zhong Qiling is big with thumb is clipped in the left hand centre of the palm, and the some combustion wire does not but reach dishes out, and firecracker explodes in the centre of the palm, centre of the palm skin, muscle and neurally seriously be wound.Come here to seek medical advice, I have little time to clear up wound surface and lose no time to apply to her with medicinal liquid, only use a medicine after three days, and palm is as excellent as before, and palmmprint is all constant.

On June 14th, (5) 1992 at dusk, Shuan Lin town, Fenyi County, Jiangxi Province 2 years old son of seven virtuous village Li Lingen less than falls in the steamed rice water of just having poured into, all takes off light with right hand epidermis from back of the body neck top under the hollow of the knee, more than body temperature 40 degree, in one day two evening of township's hospitalize, child is the mind stupor always.Morning on the 16th, because of the medical care expenses deficiency of band, hospital's refusal treatment.9 o'clock on the same day, lead the way through the people, find my family to seek medical advice, I lose no time to coat Pharmaceutical to child, and child goes to sleep peacefully after 20 minutes.Eaten one little rice of steamed bread noon.Can walk on their own in 17th, the energy stair activity was played on 18th, and wound begins healing, and it is normal that body temperature recovers gradually.To the morning on the 20th, except axillary fossa because of the muscle friction fully the healing, all the other wound surface total lengths have gone out red tender new skin.Connect from the morning on the 16th and to control the morning on the 20th, only used 4 day time, the scalding area of whole body more than 45% just obtains rehabilitation substantially, and do not stay any scars, and this is rare miracle all on the world history! This also allows me never forget in the life.

Specific embodiment

Get vegetable oil 1000g, be heated to about 120 degree in the healing pot, slowly add 50g Borneolum Syntheticum and 50g alum powder, stir while adding, after adding, continue insulated and stirred and cool off after 30 minutes, fill is standby in bottle.

Attention: during medication, hinder face and still need and make simple debridement treatment, cut off blister and slough, crust or eschar needn't be gone excision firmly, treat that medicine dissolves it.Early stage wound surface oozes out more, and day changes dressings 1～2 time, what oozes out with backsight, and 2～3d changes dressings 1 time, can change dressings in 1 week 1 time after the improvement.In addition, more only need during change dressings exudate is wiped or to be taken off the exudate thin film gently with tweezers with antiseptic gauze, can remove how much what are, hardening capacity does not remove; Wound surface contacts closely with dressing and then can not tear firmly, tear dressing gently off behind available 0.1% bromo geramine liquid or 3% hydrogen peroxide dipping, the true downright bad available shears of organizing is wiped out, and wound surface reduces stimulation or the remaining skin of damage possibility to wound surface without disinfectant as far as possible.

Claims (2)

1. Chinese prescription for the treatment of burn, scald and wound, its feature is made up of according to part by weight following raw material:

10～40 parts of vegetable oil, 1～5 part of Borneolum Syntheticum, 1～3 part of alum powder.

2. the Chinese prescription of treat burn according to claim 1, scalding and wound, the weight portion proportioning commonly used of each composition is:

20 parts of vegetable oil, 1 part of Borneolum Syntheticum, 1 part of alum powder.