CN109602854B

CN109602854B - Ointment for treating burns and scalds and preparation method thereof

Info

Publication number: CN109602854B
Application number: CN201910065767.5A
Authority: CN
Inventors: 魏国军
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-01-24
Filing date: 2019-01-24
Publication date: 2021-05-04
Anticipated expiration: 2039-01-24
Also published as: CN109602854A

Abstract

The invention relates to an ointment for treating burns and scalds and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. The ointment comprises the following raw materials in parts by weight: 6-10 parts of phellodendron, 3-6 parts of borneol, 6-10 parts of gallnut, 6-10 parts of rhubarb, 6-10 parts of astragalus, 6-10 parts of bletilla striata, 6-10 parts of garden burnet, 6-10 parts of phaseolus calcaratus, 6-10 parts of kudzu root, 6-10 parts of mint and 6-10 parts of sesame oil. The ointment can obviously reduce the secretion amount of the wound surface, stimulate the growth of fresh granulation tissues to the epidermis, accelerate the early scabbing of the wound surface, reduce the infection chance of the wound surface and simultaneously lead necrotic tissues to be quickly dissolved and shed; the analgesic effect is obvious; has strong anti-infection function and is not easy to generate drug resistance. The healing is fast, the scar is light after healing, the medicine is anti-inflammatory and anti-infection, the medicine resistance is not easy to generate, the price is economic, the source is wide, the use is convenient, and the popularization and the application are easy.

Description

Ointment for treating burns and scalds and preparation method thereof

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an ointment for treating burns and scalds and a preparation method thereof.

Background

Burn and scald are one of the common clinical diseases, which causes patients to feel hard and bitter. This is due to the destruction of the epidermis, dermis, and subcutaneous tissues of the skin, which results in the destruction of the natural barrier of the body, impaired immune defense function, increased vascular permeability, formation of microcirculation thrombosis, coagulation in the interior, blood stasis in the middle, and blebbing in the exterior. Infection is the most dangerous after burning and scalding, so the wound infection after scalding often occurs to cause inflammatory reaction. The main purposes of the medicine after burning and scalding are to resist inflammatory reaction and wound infection which may occur, improve the defense function of the immune system of the organism, prevent systemic multi-organ injury, simultaneously promote the proliferation of connective tissues and epithelial tissues, reform the skin of the wound and restore the motor functions of each system, each organ and the body of a patient to the maximum extent.

The existing treatment method mainly applies an antibacterial external medicine of western medicines, and the western medicines clinically used for treating burns and scalds are many, and have certain effects but also have many defects. For example, western medicine treatment for burns and scalds usually employs debridement, disinfection, bandaging and surgery, although it can effectively prevent and eliminate wound infection and promote wound healing. But the large-area application is still limited, the treatment time is long, toxic and side effects exist, the wound is easy to delay healing, the wound surface is infected with germs in a diversity way, and scars are left after healing. Therefore, how to overcome the defects of the prior art is a problem which needs to be solved urgently in the technical field of traditional Chinese medicines at present.

Disclosure of Invention

The invention aims to solve the defects of the prior art and provides the ointment for treating the burns and scalds and the preparation method thereof.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows:

an ointment for treating burns and scalds comprises the following raw materials in parts by weight: 6-10 parts of phellodendron, 3-6 parts of borneol, 6-10 parts of gallnut, 6-10 parts of rhubarb, 6-10 parts of astragalus, 6-10 parts of bletilla striata, 6-10 parts of garden burnet, 6-10 parts of phaseolus calcaratus, 6-10 parts of kudzu root, 6-10 parts of mint and 6-10 parts of vegetable oil.

Further, preferably, the ointment for treating burns and scalds comprises the following raw materials in parts by weight: 8 parts of phellodendron, 6 parts of borneol, 8 parts of gallnut, 10 parts of rhubarb, 8 parts of astragalus, 10 parts of bletilla striata, 10 parts of garden burnet, 10 parts of phaseolus calcaratus, 8 parts of kudzu root, 10 parts of mint and 6 parts of vegetable oil.

Further, preferably, the mint is peppermint.

Further, preferably, the vegetable oil is sesame oil.

The invention also provides a preparation method of the ointment for treating burns and scalds, which comprises the following steps:

preparing 11 Chinese herbal medicine raw materials of phellodendron, borneol, Chinese gall, rhubarb, scutellaria, bletilla striata, garden burnet, phaseolus calcaratus, kudzu root, mint and vegetable oil according to the weight parts;

grinding the prepared 11 Chinese herbal medicine raw materials, stirring and uniformly mixing the raw materials together to form paste, and obtaining the ointment for treating burns and scalds.

In the ointment, the raw materials of the traditional Chinese medicines are as follows:

phellodendron bark: bitter and cold; the functional indications are as follows: purging pathogenic fire and removing toxic substances; clear heat and dry dampness.

Borneol: pungent, bitter and slightly cold; the functional indications are as follows: induce resuscitation, refresh mind, relieve swelling and alleviate pain.

Garden burnet root: cold, bitter and acid, non-toxic; the functional indications are as follows: cool blood to stop bleeding, clear heat and remove toxicity, resolve swelling and heal wound.

Rhubarb: bitter and cold; the functional indications are as follows: purging pathogenic accumulation, clearing away heat and fire, stopping bleeding, removing toxic materials, promoting blood circulation, and dispelling blood stasis.

Astragalus root: sweet and slightly warm; the functional indications are as follows: tonify qi and raise yang, benefit qi and strengthen superficies, induce diuresis to alleviate edema, heal wound and promote tissue regeneration.

Bletilla striata: bitter, sweet and astringent; cold in nature; the functional indications are as follows: astringe to stop bleeding, resolve swelling and promote tissue regeneration.

The root of kudzu vine is sweet and pungent; the functional indications are as follows: expelling pathogenic factors from muscles and skin, allaying fever, promoting eruption of measles, promoting the production of body fluid, quenching thirst, and invigorating yang.

Gallnut: sour and astringent; the functional indications are as follows: astringe lung to reduce fire, astringe intestine to check diarrhea, astringe sweat to stop bleeding, astringe dampness to heal wound.

Small red beans: sweet and sour; the functional indications are as follows: induce diuresis to alleviate edema, remove toxicity and expel pus.

The mint is pungent and cool; the functional indications are as follows: resisting bacteria, removing toxic substance, regenerating cells, and activating blood circulation.

Sesame oil: sweet and cool; the functional indications are as follows: moisten intestines to relieve constipation, remove toxicity and promote tissue regeneration, and relieve swelling and pain.

The medicine application method of the ointment comprises the following steps: cleaning the wound, wiping off secretion around the wound with a dry cotton ball, dipping the secretion in the wound with the dry cotton ball, inspecting the wound, performing debridement treatment when the wound is found to have more necrotic tissues and is difficult to remove, and finally applying ointment and fixing with adhesive plaster. The ointment should not be too wide, slightly exceeding the wound surface, and changing the dressing every 1 to 2 days. If the secretion of the wound is not much, the dressing change time can be prolonged properly until the wound is healed.

Compared with the prior art, the invention has the beneficial effects that:

the theory of the traditional Chinese medicine considers that the burn and the scald can cause qi stagnation and blood stasis, the stasis can not lead to the obstruction, and the obstruction can lead to the pain, so that the burn and the scald patients can feel the pain of the wound; qi stagnation causes dampness accumulation, dampness accumulation causes mildew and rot, burn and scald are caused by fire toxin, fire toxin causes sores, heat toxin enters the interior, and rotten meat pus and blood causes infection and erosion at wounds. Under the guidance of the theory of traditional Chinese medicine, the burn and scald surfaces are treated by adopting Chinese herbal medicines for promoting blood circulation to remove blood stasis, clearing away heat and toxic materials, removing necrotic tissue and promoting granulation.

The ointment of the invention has the prominent advantages of treating burns and scalds mainly as follows: the wound healing agent can obviously reduce the secretion amount of the wound surface, stimulate the growth of fresh granulation tissues to the epidermis, accelerate the early scabbing of the wound surface, reduce the infection chance of the wound surface and simultaneously lead necrotic tissues to be quickly dissolved and shed; the analgesic effect is obvious; has strong anti-infection function, has strong sterilization and bacteriostasis functions on pathogenic microorganisms which are easy to infect patients, and is not easy to generate drug resistance. The advantages are mainly embodied in fast healing, light scar after healing, anti-inflammation, anti-infection, uneasy generation of drug resistance, economic price, wide source and convenient use. The anti-inflammatory needle is not needed to be used during the administration, and the antibacterial agent is taken.

From the beginning of 2016 to the present, 280 patients treated with burns and scalds were counted primarily, and 90 adults included light and severe patients. Children 190 with light and severe patients. After the ointment is used, the cure rate is 100%, the problem of scar hyperplasia does not occur, and the ointment is easy to popularize and apply.

Drawings

FIG. 1 is a photograph of a wound prior to the first application of application example 2;

FIG. 2 is a photograph of the first administration completion of application example 2;

FIG. 3 is a photograph of a first dressing change process using example 2;

FIG. 4 is a photograph of a wound before the fourth dressing change in application example 2;

FIG. 5 is a photograph of a wound before the eighth dressing change in application example 2;

FIG. 6 is a photograph of a wound before the eleventh application of application example 2;

FIG. 7 is a photograph of a wound before the fourteenth administration in application example 2;

FIG. 8 is a photograph of a wound before the first application of example 3;

FIG. 9 is a photograph of a wound before a second dressing change in application example 3;

FIG. 10 is a photograph of the wound before the third dressing change in application example 3;

FIG. 11 is a photograph of a wound before the fourth dressing change in application example 3;

fig. 12 is a photograph of the wound before the fifth dressing change in application example 3.

Detailed Description

The present invention will be described in further detail with reference to examples.

It will be appreciated by those skilled in the art that the following examples are illustrative of the invention only and should not be taken as limiting the scope of the invention. The examples do not specify particular techniques or conditions, and are performed according to the techniques or conditions described in the literature in the art or according to the product specifications. The materials or equipment used are not indicated by manufacturers, and all are conventional products available by purchase.

Example 1

An ointment for treating burns and scalds comprises the following raw materials in parts by weight: 6 parts of phellodendron, 3 parts of borneol, 6 parts of gallnut, 10 parts of rhubarb, 6 parts of astragalus, 10 parts of bletilla striata, 6 parts of garden burnet, 10 parts of phaseolus calcaratus, 6 parts of kudzu root, 10 parts of mint and 6 parts of corn oil.

Preparing 11 Chinese herbal medicine raw materials of phellodendron, borneol, Chinese gall, rhubarb, scutellaria, bletilla striata, garden burnet, phaseolus calcaratus, kudzu root, mint and corn oil according to the weight parts;

Example 2

An ointment for treating burns and scalds comprises the following raw materials in parts by weight: 10 parts of phellodendron, 5 parts of borneol, 10 parts of gallnut, 6 parts of rhubarb, 10 parts of astragalus, 6 parts of bletilla striata, 10 parts of garden burnet, 6 parts of phaseolus calcaratus, 10 parts of kudzu root, 6 parts of peppermint and 10 parts of sesame oil.

Preparing 11 Chinese herbal medicine raw materials of phellodendron, borneol, Chinese gall, rhubarb, scutellaria, bletilla striata, garden burnet, phaseolus calcaratus, kudzu root, peppermint and sesame oil according to the weight parts;

Example 3

An ointment for treating burns and scalds comprises the following raw materials in parts by weight: 8 parts of phellodendron, 4 parts of borneol, 8 parts of gallnut, 9 parts of rhubarb, 7 parts of astragalus, 9 parts of bletilla striata, 8 parts of garden burnet, 9 parts of phaseolus calcaratus, 7 parts of kudzu root, 8 parts of peppermint and 7 parts of sesame oil.

Example 4

An ointment for treating burns and scalds comprises the following raw materials in parts by weight: 8 parts of phellodendron, 6 parts of borneol, 8 parts of gallnut, 10 parts of rhubarb, 8 parts of astragalus, 10 parts of bletilla striata, 10 parts of garden burnet, 10 parts of phaseolus calcaratus, 8 parts of kudzu root, 10 parts of peppermint and 6 parts of sesame oil.

Application example 1

Wu-Chi, Man, 58 years old. The method is characterized in that the feet and heels of people are scalded by a hot water bag due to drunkenness in 2016 (12 months) in Yunnan province, the patients are diabetic patients, and the people know that even if the diabetic patients only have a few tiny small wounds, chronic skin inflammation can be caused, because the patients with poor blood sugar control have poor resistance and are easy to have bacterial infection, and peripheral circulation is poor due to angiopathy, so that skin wounds are not easy to heal; although the body of the heels of certain feet of Wubi is seriously necrotic, the medicine is applied after the wound surface is debrided, the medicine is changed every 48 hours, and the healing lasts for 20 days.

Application example 2

Wangzhi, male, half and 1 year old. The Wufeng Zhen, Zhengxiong county, province, in 2017 for 5 months, is carried on the back by a nine-year-old sister, and the patient is knocked over to put on the pig feed pan, so that the neck, back and right arm on the right side are seriously scalded to achieve deep scald. The medicine treatment in Bijie city of Guizhou province is not improved after one month of drying therapy in hospitals, the drying therapy brings great pain to children, and after medical treatment, the medicine treatment is obviously improved, and the effect is obvious. After the wound surface is debrided in our place, the patient can be healed after being applied with the medicine of the embodiment 4 of the invention for 40 days, pictures in the treatment process are shown in figures 1-7, unfortunately, because the baby family is in a hurry to go out and work, the back of the baby family takes the ointment to go out, the parents of the baby family can not see any trace after contacting the baby family, the doctor contacts the baby family to provide the pictures, the pictures are not provided all the time, and the contact is lost.

Application example 3

Song Dynasty, women, 6 years old. The method comprises the steps of hitting a kettle on fire when the person is in a home and burning, so that scalds on the back and the hip are both blisters, treating the burns in the place of the person at the first time after the scalds, discharging the blisters by using an anti-inflammatory needle during treatment, applying the medicine of the embodiment 4 of the invention, changing the medicine once every 48 hours, healing the burns within 10 days, showing pictures in the treatment process in figures 8-12, causing no scar hyperplasia after 10 healings, only showing that the skin color at the wounds is slightly pink, and restoring the skin color to be normal after a few metabolism cycles.

Application example 4

Zhu Ching, male, 3 years old. The medicine is applied to patients in Wufeng town of Zhengxiong county in Yunnan province, the patients take 10 months in 2018 by turning over boiled water in a bowl, scalding the chest to generate blisters, using an anti-inflammatory needle to remove the blisters, changing the medicine every 48 hours and healing in 6 days.

The invention also provides a test and a result in the improvement process of the ointment for treating burns and scalds.

Test 1

Raw materials: phellodendron bark, rhubarb, myrrh, dragon's blood, borneol, jaundice, red powder, elephant skin, catechu, lime, camphor, notoginseng, dragon's bone, earthworm, dandelion, mint and egg oil, and the rest is 6-10 parts by weight except 3-6 parts by weight of borneol.

The preparation method and the application method are as follows: all the raw materials are ground into fine powder, stirred and uniformly mixed together, and externally applied.

The effect is as follows: compared with example 4, the secretion amount is large, the healing time is long, and the scar phenomenon is heavier than that of example 4.

Test 2

Raw materials: phellodendron bark, rhubarb, astragalus root, frankincense, myrrh, borneol, elephant skin, catechu, camphor, notoginseng, dragon's bone, earthworm, peppermint, cuttlebone and lard, the weight portions of the components are 6-10 portions except 3-6 portions of borneol.

The effect is as follows: compared with example 4, the amount of secretion is large, healing is slow, healing time is long, and the phenomenon of scars visible to the naked eye is heavier than that of example 4.

Test 3

Raw materials: phellodendron bark, rhubarb, astragalus root, borneol, camphor, notoginseng, dragon's bone, earthworm, peppermint, Chinese angelica root, cuttlebone, salvia root, white atractylodes rhizome, corydalis tuber and sesame oil, the weight portions of all the components are 6-10 portions except that the borneol portion is 3-6 portions.

Test 4

Raw materials: phellodendron bark, rhubarb, astragalus root, borneol, sanguisorba root, Chinese gall, camphor, notoginseng, peppermint, Chinese angelica root, cuttlebone, salvia root, white atractylodes rhizome, corydalis tuber and sesame oil, the weight portions of all the components are 6-10 portions except 3-6 portions of borneol.

The formula looks like a simple process in a comparison test, the formula takes a long time to slowly search for improvement, and in order to enable the formula to achieve a certain curative effect on the wound surface faster and more effectively, the formula can achieve a perfect effect only by browsing a large number of books through long and hard research and better exerting the characteristics of each medicine. It should be noted that the above prescriptions are used many times in clinic, and the results are comprehensively evaluated, and the results are not different due to individual differences.

The improvement of each medicine is different, the proportion of the medicines is different, and different labels are omitted, so that the formula is emphasized, the curative effect of the medicine is more obvious and more intuitive when the medicine is taken for a patient for the first time compared with the prior formulas, and the proportion parameters of each medicine are refined to obtain the optimal proportion parameters.

The characteristics of the mint are not general mint, more than 5 types of mint are changed (including apple mint, pineapple mint, spearmint, peppermint, catmint and the like) when the mint is used for dispensing, the mint type is complex, the mint cannot be distinguished fundamentally if the book is not browsed in a large amount, and the mint is classified, so the whole name of the mint in the formula is 'peppermint'. The peppermint has high medicinal value, and has antiviral, antibacterial, antifungal, antiinflammatory, resistance enhancing, toxic substance removing, purifying, cell regenerating, epithelial tissue formation promoting, granulation tissue formation promoting, analgesic, and blood circulation activating effects.

In addition, the ointment prepared by replacing the sesame oil in the formula of the invention in the example 4 with the lard oil is also prepared, and the result shows that the healing time of the formula of the example 4 is faster and the phenomenon of scars can be seen slightly by naked eyes.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. An ointment for treating burns and scalds is characterized by comprising the following raw materials in parts by weight: 6-10 parts of phellodendron, 3-6 parts of borneol, 6-10 parts of gallnut, 6-10 parts of rhubarb, 6-10 parts of astragalus, 6-10 parts of bletilla striata, 6-10 parts of garden burnet, 6-10 parts of phaseolus calcaratus, 6-10 parts of kudzu root, 6-10 parts of mint and 6-10 parts of vegetable oil.

2. The ointment for treating burns and scalds according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 8 parts of phellodendron, 6 parts of borneol, 8 parts of gallnut, 10 parts of rhubarb, 8 parts of astragalus, 10 parts of bletilla striata, 10 parts of garden burnet, 10 parts of phaseolus calcaratus, 8 parts of kudzu root, 10 parts of mint and 6 parts of vegetable oil.

3. The ointment for treating burns and scalds according to claim 1 or 2, wherein the mint is peppermint.

4. The ointment for treating burns and scalds according to claim 1 or 2, wherein the vegetable oil is sesame oil.

5. The method for preparing an ointment for treating burns and scalds as claimed in claim 1 or 2, comprising the steps of: preparing 11 Chinese herbal medicine raw materials of phellodendron, borneol, Chinese gall, rhubarb, scutellaria, bletilla striata, garden burnet, phaseolus calcaratus, kudzu root, mint and vegetable oil according to the weight parts;