CN103271353B - Liver protecting and health care composition and preparation method thereof - Google Patents
Liver protecting and health care composition and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a liver protecting and health care composition and a preparation method thereof. The composition is characterized by mainly comprising the following main components in mass fraction: 0.01 to 1 part of nano red selenium, 0.3 to 2 parts of organic germanium, 5 to 10 parts of potassium magnesium aspartate, 3 to 8 parts of acidum asparticum calcium, 0.5 to 2 parts of zinc acetate, 3 to 10 parts of collagen, 5 to 20 parts of amino acid, 2 to 10 parts of vitamin C or salt, 1 to 5 parts of sweet regulator, 0.5 to 3 parts of acid regulator, 0.5 to 3 parts of preservative, and 100 to 300 parts of water; the average grain diameter of the nano red selenium is not greater than 100nm; the vitamin C salt is vitamin C sylvite or vitamin C sodium salt; the sweet regulator is selected from at least one of the trehalose, glycine, xylitol or xylooligosaccharide; the acid regulator is citric acid; and the preservative is sodium diacetate or sodium dehydroacetate. The preparation method comprises the following steps of: hydrolyzing respectively, and then uniformly mixing and standing.
Description
Technical field
The present invention relates to field of health care products, specifically a kind of liver health composition and preparation method thereof that protects.Said composition contains the humatite matter such as nanometer selenium.
Background technology
Current common liver liver-protecting product and the technology of protecting, to take Chinese medicine and extract thereof as main mostly, be aided with amino acid, vitamin etc., mostly focus on sobering up, sober-up function, from alleviating alcohol, the injury of liver is embodied and protects liver and protect the liver, ignored recovery and the raising of human body integral function, function ratio is more single.For example, Chinese patent CN101889679B discloses " a kind of composition and application in food, health food thereof with effects of relieving alcoholism and protecting liver ", the raw material that said composition contains following mass percent: curcumin 0.15-5%, zinc lactate 0.04-1.0%, glutamine 10-50%, alanine 10-50%, xylo-oligosaccharide 10-50%.Through animal experiment and human feeding trial, prove, said composition has the content that increases the interior alcohol dehydrogenase of body and acetaldehyde dehydrogenase, fast decoupled ethanol, thereby have and promote alcohol metabolism in liver, lower the effect of Ethanol concentration in rat blood and activity keto concentration, increase simultaneously human body to the tolerance of alcohol, reduce headache due to alcohol, feel sick, the discomfort such as vomiting, and reduce the infringement of alcohol to liver.Its active principle that mainly relieves the effect of alcohol is curcumin, glutamine and alanine.Although contain zinc lactate in this prescription, its content is lower, and mineral types is single, and effect is single simple; Because curcumin is water insoluble, said composition is difficult to make liquid form product.Chinese Patent Application No. 201010516560.4 discloses " a kind of have capsule-shaped food of protecting liver, nourishing the liver, anticancer, preventing cancer function and preparation method thereof ", its composition of raw materials is: pollen 90.8-363.2mg, grape pip element 90.8-363.2mg, soya bean protein 90.8-363.2mg, crataegin 90.8-363.2mg, Organic Selenium 10-50 μ g, glutinous rice capsule 100-120mg.Though contain Organic Selenium 10-50ug in this formula, content is less, and mineral types is single; Pollen wherein, grape pip element, soya bean protein, crataegin etc. need concentration extraction in the container of 80～100 ℃ respectively, the Organic Selenium of 80% concentration that Organic Selenium obtains from the first extract plant of rich selenium.Although this application does not further illustrate concrete acquisition methods, the difficulty of obtaining of its Organic Selenium well imagines, the concentration extraction of the components such as its pollen also will consume mass energy.Chinese Patent Application No. 201210116568.0 discloses a kind of " health products of Antialcoholic liver-protecting ", and it comprises: pure water 300-800g, Arabinose 5-15g, theanine 5-15g, ion thing 10-50ppm, mushroom extract 0.1-1g, green-tea extract 0.1-0.5g, curcumin 0.1-0.5g.Ion thing wherein refers to one or more the composition in ionization copper, ionization iron, ionization zinc, ionized calcium, ionization potassium, ionization selenium, ionization manganese; Wherein said green-tea extract is that polyphenol content is more than 75% green-tea extract, and the transition metal such as Tea Polyphenols chance manganese, iron, copper, zinc are perishable.Chinese patent ZL00129443.1 discloses a kind of " multielement calcium-rich liver-protecting sobering up beverage ", its main active principle is calcium ion, auxiliary components has zinc, strontium and vitamin, in " polybasic ion calcium " raw material of wherein using, contains the elements such as micro-magnesium, iron, zinc, strontium, germanium, selenium, cobalt.This beverage contains 3～8% white granulated sugar, and need to be dissolved with boiling water, and need to be 90 ℃ of above insulations 5 minutes; Not only need in the preparation to consume the energy, and in prescription due to the introducing of a large amount of white granulated sugars and essence, pigment, do not meet the healthy consumption theory of modern people's uphold nature, be more not suitable for diabetes patients.Described ionization selenium and the nanometer selenium of these two patents (application) do not belong to identical concept category, and ion compound and humatite matter do not belong to identical concept category yet.In the scope of applicant retrieval, there is not yet that to contain nanometer selenium and take humatite prime element be the main liver health product that protects.
Summary of the invention
For the deficiencies in the prior art, the technical problem that quasi-solution of the present invention is determined is that a kind of liver health composition and preparation method thereof that protects is provided.Said composition contains the humatite matter such as nanometer selenium, has good sobering up and liver protecting functions and strengthens general immunity power effect, of many uses; This preparation method adopts normal temperature and pressure to produce, and technique is simple, easy to operate, is applicable to suitability for industrialized production.
The technical scheme that the present invention solves described composition technical problem is, designs a kind of liver health composition that protects, and the mass fraction that it is characterized in that said composition forms and is mainly: 0.01～1 part, red nano selenium; 0.3～2 part of organic germanium; 5～10 parts of Potassium Magnesium Aspartatas; Asparagus amino-acid calcium 3-8 part; 0.5～2 part of zinc acetate; 3～10 parts of collagens; 5～20 parts, amino acid; 2～10 parts of vitamin C or its salt; 100～300 parts, sweet taste conditioning agent 1-5 part, 0.5～3 part of tart flavour conditioning agent, 0.5～3 part of anticorrisive agent and water; Average grain diameter≤the 100nm of described red nano selenium; Vitamin C salt is vitamin C sylvite or vitamin C sodium salt; Sweet taste conditioning agent is at least one in trehalose, glycine, xylitol or xylo-oligosaccharide; Tart flavour conditioning agent is citric acid, and anticorrisive agent is sodium Diacetate or dehydro sodium acetate.
The technical scheme that the present invention solves described preparation method's technical problem is, design a kind of preparation method who protects liver health composition, this preparation method adopts the mass fraction that protects liver health composition of the present invention to form and following technique: at normal temperatures and pressures, (1). first red nano selenium, collagen, amino acid are dissolved in water together with anticorrisive agent, after all dissolving, standing more than 24 hours, make A solution; (2). organic germanium, Potassium Magnesium Aspartata, asparagus amino-acid calcium, zinc acetate are dissolved in water together with sweet taste conditioning agent, make B solution; (3). by vitamin C or its salt and tart flavour conditioning agent with together be dissolved in water, make C solution; (4). B solution and C solution are added in the A solution after standing, and be constantly stirred to and mix, standing more than 48 hours, get its supernatant and protect liver health composition described in making.
Compared with prior art, preparation method's normal temperature and pressure of the present invention is produced, and technique is simple, easy to operate, pollution-free, and low energy consumption is easy to promote, and is applicable to suitability for industrialized production.The present invention protects that liver health composition liver protection effect is obvious, and health-care efficacy is comprehensive, and existing good sobering up and liver protecting functions, can strengthen general immunity power again; Both before can wine, edible after drinking, be also applicable to person in middle and old age and immunocompromised person edible health at ordinary times; Both can make oral liquid, tablet or capsule etc., also can be used as functional additive adds in relevant food, beverage or feed, fertilizer, of many uses.
The specific embodiment
Below in conjunction with embodiment, further narrate the present invention.
The present invention design protect liver health composition (abbreviation composition), the mass fraction that it is characterized in that said composition forms and is mainly: 0.01～1 part, red nano selenium; 0.3～2 part of organic germanium; 5～10 parts of Potassium Magnesium Aspartatas; Asparagus amino-acid calcium 3-8 part; 0.5～2 part of zinc acetate; 3～10 parts of collagens; 5～20 parts, amino acid; 2～10 parts of vitamin C or its salt; 100～300 parts, sweet taste conditioning agent 1-5 part, 0.5～3 part of tart flavour conditioning agent, 0.5～3 part of anticorrisive agent and water; Average grain diameter≤the 100nm of described red nano selenium; Vitamin C salt is vitamin C sylvite or vitamin C sodium salt; Sweet taste conditioning agent is at least one in trehalose, glycine, xylitol or xylo-oligosaccharide; Tart flavour conditioning agent is citric acid, and anticorrisive agent is sodium Diacetate or dehydro sodium acetate.
Sweet taste flavor enhancement and tart flavour conditioning agent that the present composition is selected are flavor enhancement, are also the nutritional labelings useful to human body.
For being better applicable to diabetes patient, use, the further feature of the present composition is: said composition also comprises 0.01～0.5 part of the chromium picolinate that mass fraction forms.Described sweet taste conditioning agent is at least one in trehalose, glycine, xylitol or xylo-oligosaccharide, is also applicable to diabetes patient.
For being more conducive to micro-humatite element and the nutriment of the supplementary needed by human body of general equilibrium; The further feature of the present composition is: said composition also comprises at least one in the following interpolation material that mass fraction forms: 0.01～0.5 part of manganese acetate; 0.3～1 part of 0.2～2 part of ferrous lactate or boric acid.
The composition quality mark preferred group of an embodiment of the present invention becomes: 0.01～1 part, the red nano selenium of average grain diameter≤50nm; 0.3～2 part of organic germanium (Ge-132); 5～10 parts of Potassium Magnesium Aspartatas; Asparagus amino-acid calcium 3-8 part; 0.5～2 part of zinc acetate; 0.01～0.5 part of chromium picolinate; 0.01～0.5 part of manganese acetate; 0.2～2 part of ferrous lactate; 5～20 parts, amino acid; 2～10 parts of vitamin C sodium salts; 3～10 parts of the daltonian Isin glue collagens in molecular weight≤3000; 2～5 parts of trehaloses; Xylitol 1-5 part; 0.5～3 part of citric acid; 0.3～1 part of boric acid; 100～300 parts of 0.5～3 part of dehydro sodium acetate and distilled water.
The present composition is red transparency liquid, and color is pale red from low to high with the content of red nano selenium and gradually changes to dark red; PH value is 5～6, is faintly acid, sweet mouthfeel; Be rich in multiple micro-humatite element and the nutriment useful to human body, absorption of human body utilization rate is high, edible safety, and effect is comprehensive, can liver protecting, effectively remove interior free yl, improve body immunity.
Any component raw material of the designed use of the present composition all meets the requirement of state food safe and sanitary, and has positive liver protecting health-care effect.Wherein:
Answer≤100nm of the average grain diameter of red nano selenium, the product of the preferred average grain diameter≤50nm of embodiment of the present invention red nano selenium.
Collagen, can be the corresponding collagen extracting from pig, ox, chicken etc., can be also the Isin glue collagen extracting from fish-skin, fish scale.The daltonian Isin glue collagen in embodiment of the present invention preferred molecular weight≤3000.
Amino acid, can be compound amino acid, can be also single amino acid, or the two is in conjunction with product.What the embodiment of the present invention adopted is the combination product of compound amino acid and single amino acid design proportion, and compound amino acid is to provide full nutrition, and single amino acid is that the removing toxic substances of strengthening the present composition protects the special efficacies such as liver.Single amino acid refers to a kind of of methionine, lysine, valine, threonine, glycine, glutamic acid, cystine or alanine, or the composition of two or more arbitrary proportions.
Vitamin C salt can be its sylvite or sodium salt.The sodium salt of preferred vitamin C of the present invention.It not only has ascorbic physiological function, can play the identical effect of replenishing vitamins C, and supplement sodium element, and its performance is more stable, no longer includes ascorbic highly acid, is also more conducive to other humatite matter compatible
Anticorrisive agent, can be sodium Diacetate, can be also dehydro sodium acetate; The preferred dehydro sodium acetate of the present invention.
Water, should meet drinking water quality standard, can be distilled water, deionized water, mineral water or drinking public water supply.The preferred distilled water of the embodiment of the present invention.
Minerals and vitamins is the same, is the indispensable element of human body.Mineral element is combined with enzyme, helps body metabolism.Enzyme is indispensable protein in metabolic processes, and what make enzyme activation is mineral matter.If mineral deficiency, enzyme just cannot normally be worked, and metabolic activity just stops thereupon.Mineral matter is that human body cannot produce, cannot synthesize, and required mineral matter all needs external supplementing.Early-stage Study shows, bio-absorbable utilization rate in vivo of humatite matter and security are all higher than inorganic mineral.Present composition design mix all has the experimental basis of science.Now simply be described below:
Selenium is a kind of trace element of needed by human, participates in body metabolism endoperoxide and iodine, regulates the level of iodine and the level of free radical in organism, can strengthen body diseases prevention, resistance against diseases.Though mend selenium, can effectively prevent and treat various diseases, between the nutrition dosage of selenium and toxicity dose, scope is narrow, to such an extent as to people are studying the efficient selenium product of low toxicity always for many years.Up-to-date research shows, red nanometer selenium is more better than Organic Selenium in many aspects, demonstrates the efficient feature of low toxicity.The biological effectiveness of nanometer selenium approved, and it is health food (No. 134th, hygienic food and health number 1998) that health ministry has been ratified nanometer selenium capsule.
Research shows, organic germanium, be Carboxyethyl-germanium Sesquioxide (Ge-132), almost non-toxic property, have and bring out self interferon, increase nk cytoactive, activation phagocyte, promote body to produce antitumor, anti-ageing biological action, its material using as new resource for food of China Ministry of Public Health approved.Many studies confirm that, organic germanium at lipoid peroxidization resistant, alleviate the aspects such as alcoholic liver injury and there is remarkable result.
Zinc is composition or the coenzyme of the large enzyme of human body six, 200 kinds of metalloenzyme, and general metabolism is played to wide application.These enzymes play an important role in the metabolism of tissue respiration and protein, fat, sugar and nucleic acid etc.
The more important thing is, selenium and germanium have synergy, and selenium element and zinc element also have synergy.The present composition organically combines red nano selenium, organic germanium and organic zinc, makes it in microelement-supplementing, has further strengthened three's collaborative effectiveness.
Manganese is also one of trace element of needed by human, is that several enzyme systems comprise that a composition of the specific glycosyl transferase of manganese and phosphoenolpy ruvate carboxy kinase is also essential by normal bone structure.
Chromium (trivalent) is the important composition composition of glucose tolerance factor (GTF), and it can increase the activity of insulin, participates in the synthetic and nucleic acid of protein, the metabolism of fat, reduces body fat content.Chromium can also make immune system strengthen, and improves body to undesirable condition and resistance that stress situation.Use the effect of Organic Chromium better than inorganic chromium.The machine chromium of common are has chromium picolinate, nicotinate chromium, Cr-enriched yeast etc.
Boron is to maintain one of the health of bone and calcium, phosphorus, the needed trace element of magnesium eubolism.To preventing that calcium loss, prevention of osteoporosis disease have effect, the shortage of boron can increase the weight of the shortage of vitamin D; On the other hand, boron also contributes to improve male testical sterone secretory volume, tones up the muscles, and is the indispensable nutrient of sportsman.Boron is also improved brain function, improves the effect of respond.
Amino acid is necessary base substance in human life motion, its physiological action be promote that protein is synthetic, collagen, growth hormone secretion, protection liver function, prevents hepatic disorder after drinking, improves the functions such as immunocompetence of body.
Vitamin C (VC), as the necessary vitamin of human body, has stronger antioxidation, can protect other antioxidants, in the redox metabolic response of human body, plays important regulating action.As long as VC is sufficient, VC, glutathione and-SH can form strong anti-oxidant set boxing, removes free radical, stops the toxic action of lipid peroxidation and some chemical substance, the eubolism of liver-protective detoxification ability and cell.Also the non-oxidizability of VC just, can make the selenium element reduction in sodium selenite become simple substance selenium, and then can prepare red nano selenium.
Collagen is a kind of biological polymer substance, is the nutriment that human body delays senility and must supply.
The Main Function of Potassium Magnesium Aspartata (PMA) is the aerobic metabolism process of accelerating in tricarboxylic acid cycle, eliminates the ammonia producing in motion. reduce ammonia concentration.
Trehalose is a kind of natural materials, its protective effect to bio-tissue and large biological molecule, trehalose has the effect of stabilate film (cell membrane) and protein structure and resist drying, can stop HIV to the lymphocytic destruction of T, have hypoglycemic, the effect such as protect the liver; Trehalose is natural green carbohydrate, compares with other carbohydrate, and the absorption of trehalose in human body is slow, and blood glucose response is mild, is diabetes patient's health food.
Xylitol in vivo metabolism does not need insulin to participate in, and can not make again blood glucose value raise, and can eliminate diabetes patient more than three (many drinks, diuresis, eat) symptom more, so is sweetener, nutritious supplementary pharmaceutical and the auxiliary therapeutical agent of diabetes patient's safety.
Xylo-oligosaccharide claims again wood oligose, can optionally promote the proliferation activity of intestinal bifidobacteria, and its bifidobacterium factor functional is 10-20 times of other polymerization carbohydrate; Xylo-oligosaccharide has the effect of reducing blood lipid, norcholesterol; Prevent in addition diarrhoea, constipation, opposing tumour and decompose the functions such as carcinogenic substance.
The present invention has designed the preparation method of described composition simultaneously, this preparation method adopts the mass fraction that protects liver health composition of the present invention to form and following technique: at normal temperatures and pressures, (1). first red nano selenium, collagen, amino acid are dissolved in water together with anticorrisive agent, after all dissolving, standing more than 24 hours, make A solution; (2). organic germanium, Potassium Magnesium Aspartata, asparagus amino-acid calcium, zinc acetate are dissolved in water together with sweet taste conditioning agent, make B solution; (3). by vitamin C or its salt and tart flavour conditioning agent with together be dissolved in water, make C solution; (4). B solution and C solution are added in the A solution after standing, and be constantly stirred to and mix, standing more than 48 hours, get its supernatant and protect liver health composition described in making.
The present composition increases or adjusts while having new component, and its preparation method is done corresponding adjustment.
When present composition increase has mass fraction to consist of the chromium picolinate of 0.01～0.5 part, preparation method consists of described mass fraction the chromium picolinate of 0.01～0.5 part and is dissolved in water together with tart flavour conditioning agent in preparation C solution process.
Present composition design also comprises at least one in the following interpolation material that mass fraction forms: 0.01～0.5 part of manganese acetate; When 0.3～1 part of 0.2～2 part of ferrous lactate or boric acid, preparation method is 0.01～0.5 part of manganese acetate that described mass fraction is formed or/and 0.2～2 part of ferrous lactate is dissolved in water in preparation B solution process together with sweet taste conditioning agent; Or 0.3～1 part of the boric acid of described mass fraction composition is dissolved in water in preparation C solution process together with tart flavour conditioning agent.
The present composition when designing 0.3～1 part of 0.2～2 part of 0.01～0.5 part of chromium picolinate, manganese acetate, ferrous lactate containing described mass fraction and consist of 0.01～0.5 part and boric acid simultaneously, preparation method as previously mentioned, is dissolved in water and is dissolved in water together with tart flavour conditioning agent in C solution process at preparation B solution respectively together with sweet taste conditioning agent.
Compared with prior art, preparation method of the present invention is that normal temperature and pressure is produced, and technique is simple, easy to operate, pollution-free, and low energy consumption is easy to promote, and is applicable to suitability for industrialized production.
The present composition is red transparency liquid.This is a kind of basic product.Utilize this basic product can prepare different secondary products: for example:
1. according to the Mineral Concentrations of product design, require and national Related product quality safety standard, basic product is diluted, is distributed into oral liquid or the drinks of various dose, directly drink;
2. according to the Mineral Concentrations of product design, require and national Related product quality safety standard, basic product is made to dry powdery thing through dry technologies such as conventional low temperature drying or freeze dryings, this dry powdery thing adds the excipients of pharmacy license, can make chewable tablets, buccal tablets, oral tablet, capsule or dripping pill etc.;
3. according to the Mineral Concentrations of product design, require and national Related product quality safety standard, basic product composition or its dry powdery thing are added in functional food as food function hardening agent, make health functional food, such as biscuit cake class, noodles wheaten food class, fruit drink class etc.;
4. according to the Mineral Concentrations of product design, require and national Related product quality safety standard, using basic product composition or its dry powdery thing as beauty and skin care raw material, add in beauty and skin care aqua or paste, make function beauty treatment skin-protection product;
5. according to the Mineral Concentrations of product design, require and national Related product quality safety standard, using basic product composition or its dry powdery thing as function intensified dose, add in animal feed, make function animal feed;
6. according to the Mineral Concentrations of product design, require and national Related product quality safety standard, using basic product composition or its dry powdery thing as extraordinary fertilizer, for the plantation of the extraordinary agricultural such as crops, fruit, vegetables, edible mushroom.
The present invention does not address part and is applicable to prior art.
Provide specific embodiments of the invention below.These embodiment, only for further concrete narration the present invention, do not limit the protection domain of the application's claim.
Embodiment 1
Design a kind of liver health composition that protects, its material by following mass fraction forms: 0.01 part, red nano selenium; 0.3 part of organic germanium (Ge-132); 5 parts of Potassium Magnesium Aspartatas; 3 parts of asparagus amino-acid calciums; 0.5 part of zinc acetate; 3 parts of collagens; 5 parts of compound amino acids; 0.5 part of glycine, 0.5 part of lysine, 0.5 part of threonine, 0.5 part of valine, 0.5 part of methionine, 0.5 part, glutamic acid, Catergen part; 0.5 part of trehalose; 1 part of xylo-oligosaccharide; 0.5 part of citric acid; 100 parts of dehydro sodium acetate and distilled water.
Its preparation method is:
1. under normal temperature and pressure, by red nano selenium, collagen, compound amino acid, glycine, lysine, methionine, threonine, valine, glutamic acid and 50 parts of stirring and dissolving of dehydro sodium acetate adding distil water, to all dissolving latter standing 24 hours, make A solution;
2. under normal temperature and pressure, organic germanium, Potassium Magnesium Aspartata, asparagus amino-acid calcium, zinc acetate, trehalose and 30 parts of stirring and dissolving of xylo-oligosaccharide adding distil water, to clarification, are made to B solution;
3. under normal temperature and pressure, by citric acid and the extremely clarification of 20 parts of stirring and dissolving of vitamin C adding distil water, make C solution;
4. under normal temperature and pressure, B solution and C solution are slowly joined respectively to A solution, and be constantly stirred to evenly, after standing 48 hours, its supernatant is the humatite matter that the present invention contains nanometer selenium and protects liver health composition.
The present embodiment gained protect liver health composition, what can direct packaging become 10ml/ bottle protects liver health care oral liquid, with every day 10-30ml dosage for the people daily liver healht-care that protects, also can be before drinking oral 10-20ml or/and after drinking oral 10-20ml for relieving alcoholism and protecting liver; After 100 times of said composition water or Other Drinks dilutions, can make functional health beverage.
Embodiment 2
Design a kind of liver health composition that protects, its material by following mass fraction forms: 0.1 part, red nano selenium; 1 part of organic germanium; 8 parts of Potassium Magnesium Aspartatas; 5 parts of asparagus amino-acid calciums; 1 part of zinc acetate; 5 parts of collagens; 10 parts of compound amino acids; 1 part of glycine; 0.5 part of lysine, 0.5 part of threonine, 0.5 part of valine, 0.5 part of methionine, 0.5 part, glutamic acid, 5 parts of vitamin C sodium salts; 2 parts of trehaloses; 1 part of xylitol; 1 part of citric acid; 300 parts of 1.5 parts of sodium Diacetates and distilled water.
Its preparation method is:
1. under normal temperature and pressure, by red nano selenium, collagen, compound amino acid, glycine, lysine, methionine, threonine, valine, glutamic acid and 150 parts of stirring and dissolving of sodium Diacetate adding distil water, to all dissolving latter standing 24 hours, make A solution;
2. under normal temperature and pressure, organic germanium, Potassium Magnesium Aspartata, asparagus amino-acid calcium, zinc acetate, trehalose and 80 parts of stirring and dissolving of xylitol adding distil water, to clarification, are made to B solution;
3. under normal temperature and pressure, by citric acid and the extremely clarification of 70 parts of stirring and dissolving of vitamin C sodium salt adding distil water, make C solution;
4. under normal temperature and pressure, B solution and C solution are slowly joined respectively to A solution, and be constantly stirred to evenly, after standing 48 hours, its supernatant is the present invention and protects liver health composition.
The present embodiment gained protect liver health composition, can direct packaging become the spray of small bottle packing, every day, mouth spray was 3-5 time, each 0.5-1ml protects liver health care or/and mouthful spray before and after drinking for daily; Also can dilute with water after 10 times, what be distributed into 10ml/ bottle protects liver health care oral liquid, with every day 10-30ml dosage for the daily liver healht-care that protects of people, also can be before drinking oral 10-20ml or/and after drinking oral 10-20ml for relieving alcoholism and protecting liver; After 500 times of water or Other Drinks dilutions, can make functional health beverage.
Embodiment 3
Design a kind of liver health composition that protects, its material by following mass fraction forms: 1 part, red nano selenium; 2 parts of organic germaniums; 10 parts of Potassium Magnesium Aspartatas; 8 parts of asparagus amino-acid calciums; 2 parts of zinc acetates; 10 parts of collagens; 20 parts of compound amino acids; 10 parts of vitamin C sodium salts; 2 parts of trehaloses; 3 parts of xylo-oligosaccharides; 3 parts of citric acids; 200 parts of 3 parts of dehydro sodium acetates and distilled water.
Its preparation method is:
1. under normal temperature and pressure, by red nano selenium, collagen, compound amino acid and 100 parts of stirring and dissolving of dehydro sodium acetate adding distil water, to all dissolving latter standing 24 hours, make A solution;
2. under normal temperature and pressure, organic germanium, Potassium Magnesium Aspartata, asparagus amino-acid calcium, zinc acetate, trehalose and 60 parts of stirring and dissolving of xylo-oligosaccharide adding distil water, to clarification, are made to B solution;
3. under normal temperature and pressure, by citric acid and the extremely clarification of 40 parts of stirring and dissolving of vitamin C sodium salt adding distil water, make C solution;
4. under normal temperature and pressure, B solution and C solution are slowly joined respectively to A solution, and be constantly stirred to evenly, after standing 48 hours, its supernatant is the liver health composition that protects of the present invention.
The liver health composition that protects of the present embodiment gained is high concentration composition, can adopt conventional low temperature drying or freeze drying mode to make pulvis application; Can dilute the spray that is distributed into small bottle packing after 50 times, every day, mouth spray was 3-5 time, and each 0.5-1ml protects liver health care for daily, or/and mouthful spray before and after drinking, with relieving alcoholism and protecting liver; What also can dilute with water be distributed into 10ml/ bottle after 200 times protects liver health care oral liquid, with every day 10-30ml dosage for the daily liver healht-care that protects of people, also can be before drinking oral 10-20ml or/and after drinking oral 10-20ml for relieving alcoholism and protecting liver; After 1000 times of said composition water or Other Drinks dilutions, can make functional health beverage.
Embodiment 4
Design a kind of liver health composition that protects, its material by following mass fraction forms: on the basis of mass fraction component described in embodiment 1, increase by 0.01 part of pyrrole carboxylic acid chromium; 0.01 part of manganese acetate; 0.3 part of 0.2 part of ferrous lactate and boric acid.
Its preparation method is: manganese acetate and ferrous lactate are joined in the lump in B solution and dissolved, pyrrole carboxylic acid chromium and boric acid are joined in the lump in C solution and dissolved, other method is identical with embodiment 1.
The using method of protecting liver health composition of the present embodiment gained is identical with embodiment 1.
Embodiment 5
Design a kind of liver health composition that protects, its material by following mass fraction forms: on the basis that described in embodiment 2, mass fraction material forms, increase by 0.1 part of pyrrole carboxylic acid chromium; 0.2 part of manganese acetate; 0.5 part of 1 part of ferrous lactate and boric acid.
Its preparation method is: manganese acetate and ferrous lactate are joined in the lump in B solution and dissolved, pyrrole carboxylic acid chromium and boric acid are joined in the lump in C solution and dissolved, other method is identical with embodiment 2.
The using method of protecting liver health composition of the present embodiment gained is identical with embodiment 2.
Embodiment 6
Design a kind of liver health composition that protects, its material by following mass fraction forms: on the basis forming at embodiment 3 materials, increase by 0.5 part of pyrrole carboxylic acid chromium; 0.5 part of manganese acetate; 2 parts of ferrous lactates; 1 part of boric acid; 2 parts of 3 parts of trehaloses and xylo-oligosaccharides.
Its preparation method is: manganese acetate and ferrous lactate are joined in the lump in B solution and dissolved, pyrrole carboxylic acid chromium and boric acid are joined in the lump in C solution and dissolved, other method is identical with embodiment 3;
The using method of protecting liver health composition of the present embodiment gained is identical with embodiment 3.
Embodiment 7
Design a kind of liver health composition that protects, the consisting of of its mass fraction: 0.1 part, the red nano selenium of average grain diameter≤50nm; 1 part of organic germanium (Ge-132); 8 parts of Potassium Magnesium Aspartatas; 6 parts of asparagus amino-acid calciums; 1.5 parts of zinc acetates; 0.03 part of chromium picolinate; 0.02 part of manganese acetate; 1 part of ferrous lactate; 0 part of amino acid/11; 6 parts of vitamin C sodium salts; 8 parts of the daltonian Isin glue collagens in molecular weight≤3000; 2 parts of trehaloses; 5 parts of xylitols; 1.5 parts of citric acids; 0.6 part of boric acid; 300 parts of 1.5 parts of dehydro sodium acetates and distilled water.
Its preparation method is identical with embodiment 1 or 5.The using method of protecting liver health composition of the present embodiment gained is identical with embodiment 1 or 2.
Claims (1)
1. protect a liver health composition, its material by following mass fraction forms: 0.1 part, red nano selenium; 1 part of organic germanium; 8 parts of Potassium Magnesium Aspartatas; 5 parts of asparagus amino-acid calciums; 1 part of zinc acetate; 5 parts of collagens; 10 parts of compound amino acids; 1 part of glycine; 0.5 part of lysine, 0.5 part of threonine, 0.5 part of valine, 0.5 part of methionine, 0.5 part, glutamic acid, 5 parts of vitamin C sodium salts; 2 parts of trehaloses; 1 part of xylitol; 1 part of citric acid; 300 parts of 1.5 parts of sodium Diacetates and distilled water.
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| CN106261362A (en) * | 2016-08-08 | 2017-01-04 | 南昌大学 | A kind of honeysuckle composition beverage with the liver protecting effect and preparation method |
| CN110200287B (en) * | 2019-06-29 | 2023-06-09 | 华南理工大学 | Oyster polypeptide-nano selenium particle compound with effects of dispelling effects of alcohol and protecting liver as well as preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1539330A (en) * | 2003-11-04 | 2004-10-27 | 李学珍 | Biologic foods containing trace elements in biologic state |
| CN1762380A (en) * | 2005-09-30 | 2006-04-26 | 烟台益生药业有限公司 | Nano selenium product and its preparation method |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1539330A (en) * | 2003-11-04 | 2004-10-27 | 李学珍 | Biologic foods containing trace elements in biologic state |
| CN1762380A (en) * | 2005-09-30 | 2006-04-26 | 烟台益生药业有限公司 | Nano selenium product and its preparation method |
Non-Patent Citations (2)
| Title |
|---|
| 纳米红色元素硒抑制肿瘤和提高免疫功能的作用;高学云等;《中国公共卫生》;20030331;第19卷(第3期);第309-310页 * |
| 高学云等.纳米红色元素硒抑制肿瘤和提高免疫功能的作用.《中国公共卫生》.2003,第19卷(第3期),第309-310页. |
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