CN103264781A - Liquid medicine filling system for soft bag transfusion product - Google Patents
Liquid medicine filling system for soft bag transfusion product Download PDFInfo
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- CN103264781A CN103264781A CN201310183989XA CN201310183989A CN103264781A CN 103264781 A CN103264781 A CN 103264781A CN 201310183989X A CN201310183989X A CN 201310183989XA CN 201310183989 A CN201310183989 A CN 201310183989A CN 103264781 A CN103264781 A CN 103264781A
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- 239000007788 liquid Substances 0.000 title claims abstract description 130
- 239000003814 drug Substances 0.000 title claims abstract description 69
- 238000003466 welding Methods 0.000 claims abstract description 16
- 238000007789 sealing Methods 0.000 claims abstract description 12
- 238000001802 infusion Methods 0.000 claims description 15
- 238000001179 sorption measurement Methods 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 238000004080 punching Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000005429 filling process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000003044 adaptive effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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Abstract
The invention discloses a liquid medicine filling system for a soft bag transfusion product. The system comprises a rack. A soft bag fixing unit, a filling port opening unit, a liquid medicine filling unit, a filing port clamping unit, a soft bag liquid cavity clamping unit and a filling port welding unit are arranged on the rack. By means of the liquid medicine filling system, the side wall of the filling port can be prevented from being tainted with liquid medicine during filling, and the side wall of the filling port and a filling head are prevented from being tainted with the liquid medicine during withdrawal of the filling port, so that the problem that the filling port side wall is contaminated during liquid medicine filling through the filling port is effectively solved, and the reliable heat sealing of the filling port is guaranteed.
Description
Technical Field
The invention relates to a system for filling liquid medicine into a liquid cavity through a filling opening on a soft bag liquid cavity.
Background
Conventionally, filling of a liquid chamber of a flexible bag packaging container with a liquid chemical has been generally performed through a mouthpiece provided in the liquid chamber. The mouthpiece on the liquid cavity is designed for meeting the functions of dosing and transfusion, and the section size of the mouthpiece is usually smaller, so that the problems of long liquid filling time and low production efficiency exist when the mouthpiece is used for filling liquid medicine.
To this end, chinese patent ZL200510025981.6 discloses a side or bottom fill sealed plastic infusion container which is provided with a filling port on a soft bag, beside a mouthpiece or beside a hanging bag hole at the rear, fills a medical fluid through the filling port, and closes the filling port after filling.
The special filling opening is formed in the liquid cavity of the soft bag infusion product, so that the liquid medicine can be conveniently filled, the side wall of the soft bag filling opening is required to be prevented from being stained with the liquid medicine when the liquid medicine is filled, otherwise, the heat sealing effect of the filling opening is influenced, and therefore, the problem that a proper filling system is designed for filling the liquid medicine through the filling opening needs to be solved by technical research and development personnel is solved.
Disclosure of Invention
In view of the above-mentioned needs in the prior art, an object of the present invention is to provide a liquid medicine filling system for a soft bag infusion product, which not only realizes the fast filling of liquid medicine, but also effectively prevents the liquid medicine from contaminating the side wall of the filling opening, and ensures the reliable heat sealing of the filling opening.
In order to achieve the purpose, the liquid medicine filling system of the soft bag infusion product comprises a rack, wherein a soft bag fixing unit, a filling opening unit, a liquid medicine filling unit, a filling opening clamping unit, a soft bag liquid cavity clamping unit and a filling opening welding unit are arranged on the rack; wherein,
the soft bag fixing unit adopts a soft bag fixing device on the existing soft bag transfusion product production equipment;
the liquid medicine filling unit mainly comprises a liquid medicine supply device and a filling head which are connected through a pipeline, the liquid medicine filling unit completes the filling of liquid medicine by inserting the filling head into a filling opening on the soft bag liquid cavity, and the size of the cross section of the filling head is smaller than that of an inner cavity of the opened filling opening, so that the filling head can be inserted into or withdrawn from the filling opening without contacting the side wall of the filling opening;
the filling opening unit mainly comprises a control device, a vacuum pump, a pair of vacuum adsorption heads and a driving mechanism thereof, wherein the pair of vacuum adsorption heads are used for respectively adsorbing two side walls of the filling opening so as to open the filling opening;
the filling opening clamping unit mainly comprises a pair of clamping plates and a driving mechanism thereof, after the filling head is inserted into the opened filling opening, the pair of clamping plates clamp the side wall of the filling opening, so that the two side walls of the filling opening are opposite to each other and are wrapped on the outer side wall of the filling head from the periphery, meanwhile, the side walls of the filling opening wrapping the residual amount of the filling head are mutually attached together, and correspondingly, the clamping plates are provided with clamping openings matched with the cross section shape of the filling head;
the soft bag liquid cavity clamping unit mainly comprises a pair of chucks and a driving mechanism thereof, after liquid medicine is filled in the soft bag liquid cavity, the pair of chucks clamp two side walls of the liquid cavity below the filling head and above the liquid level of the liquid medicine together so as to isolate the liquid level of the liquid medicine from the filling opening and the filling head;
the filling opening welding unit mainly comprises a control device, a welding mould and a driving mechanism thereof, wherein after a pair of chucks are clamped on the soft bag liquid cavity, a pair of clamping plates are moved away, and the filling head is withdrawn from the filling opening, the welding mould is used for carrying out heat sealing on the filling opening;
the driving mechanism adopts a known mechanical operation mechanism or a known driving mechanism consisting of a guide device and an air cylinder or a hydraulic cylinder.
Further, the cross section of the filling head is flat-mouth-shaped.
Furthermore, a flexible layer is further arranged on the clamping working surface of the clamping plate.
Furthermore, the clamping openings of the pair of clamping heads are linear, the clamping working surface of at least one of the two clamping heads is strip-shaped, and the size of the strip-shaped vertical direction is as small as possible under the condition that the side wall of the soft bag liquid cavity is not damaged during clamping.
Further, a flexible layer is arranged on the clamping working surface of at least one of the pair of clamping heads.
The liquid medicine filling system utilizes the clamping plates to wrap the side wall of the filling opening of the soft bag liquid cavity on the outer side wall of the filling head, and meanwhile, the side walls of the filling opening which are wrapped by the left side and the right side of the filling head and are left and the rest are mutually attached together, so that the liquid medicine is prevented from being infected on the side wall of the filling opening in the filling process; after filling, the liquid medicine is separated from the filling opening and the filling head by using the clamping head, so that the liquid medicine which is fluctuated when the filling head is withdrawn is prevented from being polluted on the side wall of the filling opening and the filling head; the size of the inner cavity of the suction opening of the filling head is larger than the size of the cross section of the filling head, so that a condition is created for the filling head to withdraw from the filling opening under the condition of not contacting the side wall of the filling opening, and at the moment, even if the lower end of the filling head is contaminated with liquid medicine, the contaminated liquid medicine cannot pollute the side wall of the filling opening in the withdrawal process; therefore, the invention effectively solves the problem that the side wall of the filling opening is polluted when the liquid medicine is filled through the filling opening, and ensures the reliable heat sealing of the filling opening.
Drawings
FIG. 1 is a schematic view of a single liquid chamber and single interface tube soft bag structure;
fig. 2a is a schematic diagram of the liquid medicine filling system according to the present invention;
fig. 2b is an enlarged sectional view a-a of the liquid medicine filling unit 5 in fig. 2 a;
fig. 2c is a partially enlarged view of the filling opening holding unit 7 in fig. 2 a;
FIG. 3 is a schematic top view of a vacuum suction head prior to opening a fill port in a soft bag liquid chamber;
FIG. 4 is a schematic view of the filling opening after it has been sucked open;
fig. 5 is a schematic view after insertion of a filling head into a filling opening;
FIG. 6 is a schematic view of the filling opening before the filling opening is clamped by a pair of clamping plates;
FIG. 7 is a schematic view of the clamp plate after clamping to the filling opening;
FIG. 8 is a schematic side view of the clamp plate after clamping to the fill port;
FIG. 9 is a schematic view of the soft bag liquid chamber after filling with liquid medicine;
FIG. 10 is a schematic illustration of the flexible bag liquid chamber prior to clamping beneath the filling head with a pair of clamps;
FIG. 11 is a schematic view of the clamp head clamping together the two side walls of the soft bag chamber below the filling head;
fig. 12 is a schematic view of the withdrawal of the filling head from the filling opening;
FIG. 13 is a schematic view of the use of a welding die and a punching die to heat seal the filling opening and punch the hanging bag hole;
fig. 14 is a schematic view of a finished product of a single-liquid-cavity double-mouth-tube soft bag infusion product.
Detailed Description
The invention is further described below with reference to the accompanying drawings.
Fig. 1 is a schematic structural diagram of a soft bag to be filled by the soft bag infusion product liquid medicine filling system of the present invention, and it can be seen from the diagram that a liquid chamber 3 enclosed by a sealing edge 2 is arranged on the soft bag 1, and a filling opening 4 formed by a reserved unsealed gap is arranged on the liquid chamber 3. Referring to fig. 3, before filling the liquid medicine, two side walls of the soft bag liquid cavity 3 are attached together and are in a sheet shape.
The structure of the liquid medicine filling system of the soft bag infusion product is shown in figure 2.
The soft bag transfusion product filling system comprises a rack, wherein a soft bag fixing unit, a filling opening unit 6, a liquid medicine filling unit 5, a filling opening clamping unit 7, a soft bag liquid cavity clamping unit 8 and a filling opening welding 9 are arranged on the rack.
Because the components in the system of the present invention may be disposed on a common frame or on separate frames, and the frames may be in the form of a base or a support, and the switching of the components during the filling process of the liquid medicine may be performed by using a known robot or a known driving mechanism including a guiding device and an air cylinder or a hydraulic cylinder, and the arrangement of the components may be different depending on the switching means, a specific frame structure is not shown in fig. 2.
In addition, the existing soft bag infusion product production equipment is provided with corresponding soft bag fixing devices, the fixing devices can be soft bag fixing clamps moving along with the production line and can also be soft bag fixing devices fixed on stations, and the existing soft bag fixing devices can be applied to the filling system of the invention directly or only by simple adaptive adjustment, so that the specific structure of the soft bag fixing unit is not shown in fig. 2.
When the soft bag to be filled with the liquid medicine is of a single liquid cavity structure, and the filling port on the liquid cavity is arranged on the bottom edge of the soft bag in a centering manner, the hanging bag hole is usually also arranged on the bottom edge of the soft bag in a centering manner, so that the filling system in the invention in fig. 2 is also provided with a soft bag hanging bag hole punching unit 10. The punching unit 10 for punching holes of punching bags mainly comprises a pair of punching dies 101 and a cylinder 102 for driving the punching dies 101 to operate.
The liquid medicine filling unit 5 mainly includes a liquid medicine supply device 51 and a filling head 52 connected by a pipe, and the cross section of the filling head 52 is a flat nozzle as shown in a-a in the figure. The liquid medicine filling unit 5 completes the filling of the liquid medicine by inserting the filling head 52 into the filling port 4 on the soft bag liquid chamber 3. Referring to fig. 5, the cross-sectional dimension of the filling head 52 is smaller than the inner cavity dimension of the filling opening 4 after opening, so that the filling head 52 can be inserted into or withdrawn from the filling opening 4 without contacting the side wall of the filling opening 4.
The filling port opening unit 6 mainly includes a control device 61, a vacuum pump 62, a pair of vacuum suction heads 63, and a driving cylinder 64 thereof. Referring to fig. 4 and 5, the filling opening unit 6 opens the filling opening 4 by respectively sucking both side walls of the filling opening 4 by a pair of vacuum suction heads 63.
The filling opening clamping unit 7 mainly comprises a pair of clamping plates 71 and a driving air cylinder 72 thereof, wherein the clamping plates 71 are provided with clamping openings 73 matched with the cross section shapes of the filling heads 52, and meanwhile, the clamping working surfaces of the clamping plates 71 are also provided with flexible layers 74 made of flexible materials. Referring to fig. 6 and 7, after the filling head 52 is inserted into the opened filling opening 4, a pair of clamping plates 71 clamp the side walls of the filling opening 4, so that the two side walls of the filling opening 4 are opposite to each other and wrap around the outer side wall of the filling head 52, and meanwhile, the side walls of the filling opening 4 wrapping the rear margin of the filling head 52 are attached to each other.
The soft bag liquid chamber holding unit 8 mainly includes a pair of chucks 81 and a driving cylinder 82 thereof. Referring to fig. 10 and 11, after the soft bag liquid chamber 3 is filled with the liquid medicine, the pair of clamp heads 81 clamp the two side walls of the liquid chamber 3 below the filling head 52 and above the liquid level of the liquid medicine together, thereby isolating the liquid level of the liquid medicine from the filling port 4 and the filling head 52 above the liquid level.
The filling opening welding unit 9 mainly includes a control device 91, a welding mold 92 and a driving cylinder 93 thereof. Referring to fig. 13, after the pair of clamps 81 are clamped to the flexible bag liquid chamber 3, the pair of clamps 71 are removed, and the filling head 52 is withdrawn from the filling opening 4, the welding mold 92 heat seals the filling opening 4.
It is to be noted that the drive mechanism constituted by the drive cylinder in each unit described above may be replaced by a known robot operation mechanism, a drive device constituted by a guide device and a cylinder or a hydraulic cylinder may be used, a known screw drive device may be used, or the like.
In fig. 2, the cross-sectional shape of the filling head 52 is a flat nozzle, but a circular tube-shaped filling head and other filling heads having an appropriate cross-sectional shape may be used.
The function of the chuck 81 is to isolate the liquid medicine in the soft bag liquid chamber 3 from the filling port 4 and the filling head 52, and firstly, to prevent the liquid medicine from vibrating from contaminating the side wall of the filling port 4 when the filling head 52 is withdrawn from the filling port 4; secondly, after the side walls of the soft bag liquid cavity 3 are clamped together, the heat sealing operation of the welding mold 92 is facilitated, and the phenomenon that the two side walls of the soft bag liquid cavity 3 are opened towards two sides to influence the heat sealing quality is avoided. The side wall above the liquid level in the liquid cavity 3 is clamped by the chuck 81, and because cavities above the liquid level of liquid medicine in some soft bag liquid cavities are smaller, if the width of a clamping edge formed after the clamping of the chuck 81 is too large, the volume of the soft bag liquid cavity 3 is reduced too much, so that the liquid medicine rises to the filling opening 4, therefore, in order to avoid the liquid medicine from rising to pollute the side wall at the filling opening 4, the width of the clamping edge formed after the clamping of the chuck 81 is required to be as small as possible under the condition that the side wall of the soft bag liquid cavity 3 is not damaged. To this end, the collet 81 may be formed from two laterally opposed sheets as shown in FIG. 2; or a thin plate and a clamping seat, the thin plate clamps two side walls of the liquid cavity 3 by utilizing the side edges of the thin plate to be matched with the clamping working surface on the clamping seat, the width of the clamping edge is determined by the thickness of the thin plate, and the width of the clamping working surface on the clamping seat can be a plane or a long-strip-shaped surface with the same width as the thickness of the thin plate. Furthermore, the flexible layer made of flexible material can be disposed on the clamping working surface of at least one of the clamping heads 81 to avoid damaging the side wall of the liquid chamber 3 during clamping.
The thickness direction of the flaky soft bag liquid cavity 3 is taken as the front-back direction, and the working process of the soft bag transfusion product liquid medicine filling system is as follows:
fixing a soft bag 1 to be filled with liquid medicine on a soft bag fixing unit;
as shown in fig. 3 and 4, two vacuum adsorption heads 63 adsorb two side walls attached together at the soft bag filling opening 4, and suck the filling opening 4 open;
as shown in fig. 5, the filling head 52 is inserted into the filling opening 4;
as shown in fig. 6, 7 and 8, the adsorbed side walls of the filling opening 4 are released, the vacuum adsorption head 63 is removed, and the side walls of the filling opening 4 are clamped by a pair of clamping plates 71 from front to back, so that the two side walls of the filling opening 4 are opposite to each other and wrap the outer side wall of the filling head 52 from the periphery, and meanwhile, the side walls of the filling opening 4 which are positioned at the left side and the right side of the filling head 52 and the rest are attached to each other; fig. 8 is a side view of the clamping plate 71 after clamping the filling opening 4;
as shown in fig. 9, a predetermined amount of liquid medicine is filled into the soft bag liquid chamber 3 by the filling head 52;
as shown in fig. 10 and 11, the two side walls of the soft bag liquid chamber 3 below the filling head 52 are clamped together by a pair of clamping heads 81 from the front-back direction, and thus the liquid medicine in the liquid chamber 3 is isolated from the filling port 4 and the filling head 52 above the same;
as shown in fig. 12, and with reference to fig. 5, the clamp plate 71 is opened and removed, the filling opening 4 is again sucked open by the vacuum suction head 63, and the filling head 52 is withdrawn from the filling opening 4 without contacting the side wall of the filling opening 4;
as shown in fig. 13, the sucked sidewall of the filling port 4 is released, the vacuum suction head 63 is removed, and the filling port 4 is heat-sealed by the welding mold 92; meanwhile, punching a hanging bag hole on the outer side of the heat sealing edge of the filling opening 4 by a punching die 101;
finally, the clamp 81 is opened and removed to complete the liquid medicine filling of the soft bag infusion product.
The prepared soft bag infusion product is shown in figure 14, wherein a filling opening 4 on a soft bag liquid cavity 3 is hermetically sealed by a heat sealing edge 4-1, and a hanging bag hole 4-2 is arranged at the outer side of the heat sealing edge 4-1.
The above is the preferred embodiment of the present invention, the soft bag in the example is only one of the many soft bags filled by the present invention, the filling method of the present invention can also be applied to various soft bag infusion products such as a dual-fluid-cavity soft bag infusion product, a multi-fluid-cavity soft bag infusion product with a powder adding cavity, etc., and the filling port on the soft bag can also be located beside the mouthpiece, between two mouthpiece, etc., as long as the soft bag with the liquid medicine filling port is the applicable object of the present invention.
Claims (5)
1. A liquid medicine filling system of a soft bag infusion product is characterized by comprising a rack, wherein a soft bag fixing unit, a filling port opening unit, a liquid medicine filling unit, a filling port clamping unit, a soft bag liquid cavity clamping unit and a filling port welding unit are arranged on the rack; wherein,
the soft bag fixing unit adopts a soft bag fixing device on the existing soft bag transfusion product production equipment;
the liquid medicine filling unit mainly comprises a liquid medicine supply device and a filling head which are connected through a pipeline, the liquid medicine filling unit completes the filling of liquid medicine by inserting the filling head into a filling opening on the soft bag liquid cavity, and the size of the cross section of the filling head is smaller than that of an inner cavity of the opened filling opening, so that the filling head can be inserted into or withdrawn from the filling opening without contacting the side wall of the filling opening;
the filling opening unit mainly comprises a control device, a vacuum pump, a pair of vacuum adsorption heads and a driving mechanism thereof, wherein the pair of vacuum adsorption heads are used for respectively adsorbing two side walls of the filling opening so as to open the filling opening;
the filling opening clamping unit mainly comprises a pair of clamping plates and a driving mechanism thereof, after the filling head is inserted into the opened filling opening, the pair of clamping plates clamp the side wall of the filling opening, so that the two side walls of the filling opening are opposite to each other and are wrapped on the outer side wall of the filling head from the periphery, meanwhile, the side walls of the filling opening wrapping the residual amount of the filling head are mutually attached together, and correspondingly, the clamping plates are provided with clamping openings matched with the cross section shape of the filling head;
the soft bag liquid cavity clamping unit mainly comprises a pair of chucks and a driving mechanism thereof, after liquid medicine is filled in the soft bag liquid cavity, the pair of chucks clamp two side walls of the liquid cavity below the filling head and above the liquid level of the liquid medicine together so as to isolate the liquid level of the liquid medicine from the filling opening and the filling head;
the filling opening welding unit mainly comprises a control device, a welding mould and a driving mechanism thereof, wherein after a pair of chucks are clamped on the soft bag liquid cavity, a pair of clamping plates are moved away, and the filling head is withdrawn from the filling opening, the welding mould is used for carrying out heat sealing on the filling opening;
the driving mechanism adopts a known mechanical operation mechanism or a known driving mechanism consisting of a guide device and an air cylinder or a hydraulic cylinder.
2. The system of claim 1, wherein the filling head is flat-nose shaped in cross-section.
3. The system of claim 1, wherein the clamping face of the clamping plate is further provided with a flexible layer.
4. The system of claim 1, wherein the gripping openings of the pair of gripping heads are linear, and wherein the gripping surface of at least one of the gripping heads is elongated with an up-down dimension that is as small as possible while ensuring gripping without damaging the sides of the flexible bag chamber.
5. The system of claim 4, wherein the gripping face of at least one of the pair of jaws is provided with a flexible layer thereon.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310183989.XA CN103264781B (en) | 2013-05-17 | 2013-05-17 | Liquid medicine filling system for soft bag transfusion product |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310183989.XA CN103264781B (en) | 2013-05-17 | 2013-05-17 | Liquid medicine filling system for soft bag transfusion product |
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| CN103264781A true CN103264781A (en) | 2013-08-28 |
| CN103264781B CN103264781B (en) | 2014-10-29 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105253337A (en) * | 2015-11-23 | 2016-01-20 | 长春恒驰科技有限公司 | Soft bag filling mechanism, soft bag filling method and infusion soft bag production line |
| CN107244436A (en) * | 2017-06-27 | 2017-10-13 | 上海鸿研物流技术有限公司 | Aid in filling apparatus and liquid filling system and method for filling of liquid |
| CN107914917A (en) * | 2017-12-06 | 2018-04-17 | 佛山市尊聚自动化设备有限公司 | A kind of bag film clasps mechanism |
| CN111572880A (en) * | 2020-06-02 | 2020-08-25 | 王撑 | Polypropylene infusion canning device and canning method thereof |
| CN112168695A (en) * | 2020-10-28 | 2021-01-05 | 四川极智朗润科技有限公司 | Opening device for soft liquid bag hose |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111572880A (en) * | 2020-06-02 | 2020-08-25 | 王撑 | Polypropylene infusion canning device and canning method thereof |
| CN111572880B (en) * | 2020-06-02 | 2021-03-23 | 吉林省都邦药业股份有限公司 | Polypropylene infusion filling device and filling method thereof |
| CN112168695A (en) * | 2020-10-28 | 2021-01-05 | 四川极智朗润科技有限公司 | Opening device for soft liquid bag hose |
| CN112168695B (en) * | 2020-10-28 | 2024-04-16 | 四川极智朗润科技有限公司 | Opening device of soft liquid bag hose |
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| Publication number | Publication date |
|---|---|
| CN103264781B (en) | 2014-10-29 |
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