CN103263555A - Medicine for treating dysfunctional uterine bleeding and preparation method thereof - Google Patents
Medicine for treating dysfunctional uterine bleeding and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating dysfunctional uterine bleeding and a preparation method thereof. The medicine disclosed by the invention is prepared from the following medicines according to a certain weight ratio: codonopsis pilosula, astragalus membranaceus, scutellaria baicalensis, golden cypress, radix rehmanniae recen, radix paeoniae alba, sophora flower, garden burnet, pollen typhae, rhizoma cyperi, tortoise plastron, chrysanthemum, prepared rehmannia root, American ginseng, liquorice, moutan bark, Yunnan supplejack root and the like. The medicine disclosed by the invention has the functions of tonifying qi, consolidating, clearing heat, cooling blood, invigorating the circulation of blood, dispersing blood stasis, stopping bleeding and relieving desertion. For treating dysfunctional uterine bleeding, the medicine disclosed by the invention takes effect quickly, prevents recurrence of dysfunctional uterine bleeding and is high in curative rate.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of metrorrhagia and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Dysfunctional uterine bleeding is called for short metrorrhagia, and metrorrhagia also claims metrorrhagia, sudden onset of metrorrhagia, refers to the women not in menstrual period and the acute disease of unexpected heavy vaginal bleeding.Metrorrhagia is one and is commonly called as, the situation of narrating is often referred to: the speed that blood flow comes out is as tap water, the medicine of the method for doctor trained in Western medicine hemostasis such as mosquito forceps, compression method or help blood coagulation, all used down, still do not improve, sometimes the doctor may know hemorrhage place, but can't effectively stop blooding; Sometimes the doctor does not know hemorrhage place or reason, only see blood and in lower body, flow out, and during at this moment patient's life is in jeopardy, at any time can be because of severe loss of blood, the blood pressure deficiency, and produce shock.Women's life security and healthy in the metrorrhagia serious harm.At present, because Western medicine can't effectively be treated metrorrhagia, therefore, there is great demand in people to the Chinese medicine of effective treatment metrorrhagia.
Summary of the invention
The inventor has found the medicine of effective treatment metrorrhagia finally, thereby has finished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.
Purpose of the present invention just provides a kind of composition of medicine for the treatment of dysfunctional uterine bleeding.
Another object of the present invention has just provided the preparation method of this composition of medicine.
Medicine of the present invention is to select Radix Codonopsis, the Radix Astragali, Radix Scutellariae, Cortex Phellodendri, Radix Rehmanniae, the Radix Paeoniae Alba, Flos Sophorae, Radix Sanguisorbae, Pollen Typhae, Rhizoma Cyperi, Carapax et Plastrum Testudinis, Cortex Ailanthi, Fructus Mume, Radix Artemisia ordosicae, Fibra Trachycarpi, Radix Angelicae Sinensis, Concha Ostreae, Os Draconis, Colla Corii Asini, Cortex Lycii, Flos Chrysanthemi, Radix Rehmanniae Preparata, Radix Panacis Quinquefolii, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Poria, Fructus Corni, the Cortex Eucommiae, Radix Polygalae, Fructus Schisandrae Chinensis, Cortex Moutan, Radix Bupleuri, Semen Plantaginis, Radix Berchemiae Yunnanensis, Herba Commelinae, the Cortex Phellodendri medicine makes up, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat dysfunctional uterine bleeding.Wherein select for use Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, the meridian of Foot-TAI YIN edema caused by disorder of QI, invigorating the spleen and replenishing QI is arranged, the function of promoting the production of body fluid is controlled weakness of the spleen and stomach, deficiency of both QI and blood, and fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.Select for use the Radix Astragali to be because its nature and flavor are sweet, tepor is gone into lung, spleen channel, give birth to the useful consolidating superficial resistance of defending, and inducing diuresis to remove edema, poison holding, the function of granulation promoting is controlled spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle are not burst or are burst and hold back for a long time; Process with the function that the invigorating middle warmer benefit is arranged, control the internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select for use Radix Scutellariae to be because its nature and flavor hardship is cold, go into the heart, lung, gallbladder, large intestine channel, the removing the relative excess fire is arranged, except damp and hot, hemostasis, antiabortive function is controlled the high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria is told, is defeated in battle, collapses, is leaked, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.Select for use Cortex Phellodendri to be because its nature and flavor hardship is cold, go into kidney, urinary bladder channel, heat clearing away is arranged, dampness, pathogenic fire purging, the function of detoxifcation, control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice ， flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid are had blood in stool, leucorrhea with red and white discharge, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.Select for use Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid is controlled the calentura excessive thirst, interior-heat caused by deficiency of YIN, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.Selecting the Radix Paeoniae Alba for use is that liver, spleen channel are gone in cold, and nourishing blood to suppress the hyperactive liver is arranged because of its nature and flavor picric acid, slow middle pain relieving, and yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Selecting Flos Sophorae for use is that liver, large intestine channel are gone in cold, and heat clearing away is arranged because of its nature and flavor hardship, removing heat from blood, and the function of hemostasis is controlled discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, epistaxis, under the dysentery with red and white feces, the wind heat conjunctival congestion, carbuncle storehouse poison, and be used for prevention of stroke.Select for use Radix Sanguisorbae to be because its nature and flavor picric acid, cold.Go into liver, large intestine channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing.Control haematemesis, epistaxis, dysentery, collapse, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.Select for use Pollen Typhae to be because its nature and flavor are sweet arduous, liver, heart channel are gone in cold, and cooling blood for hemostasis is arranged, the function of activating blood circulation and dissipating blood stasis is given birth to controlling amenorrhea and is suffered from abdominal pain, and postpartum stagnation is had a pain, and falls that to pounce on blood vexed, the furuncle toxic swelling is fried black emesis blood, epistaxis, metrorrhagia, rush down blood, hematuria, dysentery, leukorrhagia, external treatment congenital deformity of the tongue, aphtha, the Ting discharging ear, hemorrhage in the ear, uncontrolled urination is itched.Select for use Rhizoma Cyperi to be because the hot little hard work of its nature and flavor is flat, go into liver, tri-jiao channel, the resolving depression of regulating the flow of vital energy, the function of pain relieving regulating menstruation, treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.Select for use Carapax et Plastrum Testudinis to be because its nature and flavor are salty sweet, flat, go into liver, kidney channel, YIN nourishing is arranged, YANG hyperactivity suppressing, the kidney invigorating, the function of strong bone is controlled deficiency of kidney yin, the hectic fever due to YIN-deficiency consumptive fever is spitted blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.Select for use Cortex Ailanthi to be because its nature and flavor bitterness is cold, go into stomach, large intestine channel, heat clearing away is arranged, dampness, astringing intestine to stop diarrhea, hemostasis, the function of parasite killing is controlled chronic dysentery, chronic diarrhea, discharging fresh blood stool, metrorrhagia, leukorrhagia, seminal emission, nebulousurine, ascarid.Selecting Fructus Mume for use is that temperature is gone into liver because of its nature and flavor acid, spleen, and lung, large intestine channel has convergence to promote the production of body fluid, and the function of relieving colic caused by ascaris anthelmintic is controlled chronic cough, the deficiency-heat excessive thirst, chronic malaria, dysentery is had blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, ancylostomiasis, psoriasis, bulbar conjunctiva polyp.Select for use Radix Artemisia ordosicae to be because its nature and flavor hardship is cold, heat clearing away is arranged, detoxifcation, the function of hemostasis is controlled the hectic fever due to YIN-deficiency consumptive fever, spits blood epistaxis.Select for use Fibra Trachycarpi to be because its nature and flavor hardship, puckery, flat is returned lung, liver, large intestine channel, the function of hemostasis with astringents is arranged, control haematemesis, epistaxis is had blood in stool, metrostaxis, metrorrhagia.Selecting Radix Angelicae Sinensis for use is that temperature is gone into the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after the bloody dysentery, ulcer sores, incised wound, injury from falling down.Select for use Concha Ostreae to be because its nature and flavor are salty and bitter, liver, kidney channel are gone in cold, and yin fluid astringing is arranged, YANG hyperactivity suppressing, and hidroschesis, arresting seminal emission reduces phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select for use Os Draconis to be because its property sweet-puckery flavor is flat, be included into the heart, liver, kidney, large intestine channel, tranquillizing the mind by relieving convulsion is arranged, the function of arresting sweating controlling nocturnal emission with astringent drugs, it is demented to control frightened Epilepsy, and palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating is had blood in stool, metrorrhagia.Select for use Colla Corii Asini to be because its nature and flavor are sweet flat, go into lung, liver, kidney channel, nourishing YIN and supplementing blood is arranged, antiabortive function is controlled blood deficiency, and cough due to consumptive disease, is had blood in stool at haematemesis, epistaxis, menoxenia, and metrorrhagia is controlled leakage.Select for use Cortex Lycii to be because its nature and flavor are sweet, cold, go into lung, liver, kidney channel, heat clearing away is arranged, the function of removing heat from blood is controlled asthenia hectic fever night sweat, and the lung-heat cough with asthma is spitted blood, epistaxis, stranguria with blood is quenched one's thirst, hypertension, carbuncle, malignant boil.Selecting Flos Chrysanthemi for use is that lung is gone in cold because of its nature and flavor sweetness and bitterness, and Liver Channel has dispelling wind, and the heat that disappears makes eye bright, and the function of detoxifcation is controlled headache, and is dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.Select for use Radix Rehmanniae Preparata to be because its nature and flavor are sweet, tepor is gone into liver, kidney channel, and YIN nourishing is arranged, and the function of enriching blood is controlled deficiency of YIN insufficiency of blood, the waist knee flaccidity, and the chronic cough hectic fever due to YIN-deficiency, seminal emission, metrorrhagia, menoxenia is quenched one's thirst, frequency of micturition, deafness, blurred vision.Selecting Radix Panacis Quinquefolii for use is that the heart, lung, kidney three warps are gone in cold because of its property sweet and slightly bitter taste, useful lung yin, and clear asthenic fire, the function of promoting the production of body fluid to quench thirst is controlled deficiency of the lung chronic cough, loses blood, dry throat and mouth, deficiency-heat is tired tired.Select for use Radix Glycyrrhizae to be because its nature and flavor are sweet flat, go into spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, the overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle is given birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.Selecting the Rhizoma Atractylodis Macrocephalae for use is because its property bitter but sweet flavor, and temperature is gone into spleen, stomach warp, and spleen reinforcing is arranged, stomach reinforcing, dampness and in function, control deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension is had loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea uneasiness.Select for use Poria to be because its property slightly sweet flavor is flat, go into the heart, spleen, lung meridian, eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming is controlled dysuria edema distending pain, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Selecting Fructus Corni for use is that tepor has invigorating the liver and kidney because of its nature and flavor acid, and the function of arresting seminal emission gas is controlled sexual impotence, seminal emission, and the deficiency of the liver cold and heat, the heart shakes scattered pulse.Selecting the Cortex Eucommiae for use is that temperature is gone into liver, kidney channel, and invigorating the liver and kidney is arranged because of the sweet little suffering of its nature and flavor, bone and muscle strengthening, and antiabortive function is controlled the spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is desired to fall, hypertension.Selecting Radix Polygalae for use is that temperature is gone into the heart, kidney channel, and the Fructus Alpiniae Oxyphyllae of calming the nerves is arranged, and eliminates the phlegm because of its nature and flavor toil, and the function of resolving depression is controlled palpitation with fear, and is forgetful, nocturnal emission, and insomnia, cough ant phlegm, the carbuncle skin ulcer is swollen.Selecting Fructus Schisandrae Chinensis for use is that temperature is gone into lung, kidney channel, astringes the lung because of its nature and flavor acid, and nourishing kidney is promoted the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission is controlled the deficiency of the lung and breathed with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Select for use male Cortex Moutan to be because its nature and flavor are arduous, the heart, liver, kidney channel are gone in cold, and heat clearing away is arranged, removing heat from blood, and blood, and the function of repercussive is controlled the pathogenic heat attacking blood system in febrile diseases, sends out speckle ， Jing Epilepsy, and tell, be defeated in battle, have blood in stool, the hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer is pounced on damage.Selecting Radix Bupleuri for use is that liver, gallbladder meridian are gone in cold, and reconciling superficies and interior is arranged, and be soothing the liver because of its nature and flavor hardship, and the function of yang invigorating is controlled alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste deafness, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse.Select for use Semen Plantaginis to be because its nature and flavor are sweet, cold, go into kidney, urinary bladder channel, diuretic is arranged, heat clearing away makes eye bright, and the function of eliminating the phlegm is controlled urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, the heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.Select for use Radix Berchemiae Yunnanensis to be because its nature and flavor are sweet, light, flat, heat clearing away is arranged, the function of dampness removing is controlled dysentery, jaundice, pyretic stranguria, metrorrhagia, leukorrhagia.Select for use Herba Commelinae to be because it is sweet in flavor and cold in property, heat clearing away is arranged, removing heat from blood, the function of detoxifcation is controlled hematodiarrhoea, hematuria, leucorrhea, metrorrhagia.Select for use Cortex Phellodendri to be because its nature and flavor hardship is cold, go into kidney, urinary bladder channel, heat clearing away is arranged, dampness, pathogenic fire purging, the function of detoxifcation, control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice ， flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid are had blood in stool, leucorrhea with red and white discharge, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.
The specific embodiment
The drug dose of component of the present invention also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in following weight range
Radix Codonopsis 10-15 gram Radix Astragali 10-15 gram Radix Scutellariae 10-15 gram
Cortex Phellodendri 15-20 gram Radix Rehmanniae 10-20 gram Radix Paeoniae Alba 8-12 gram
Flos Sophorae 8-12 gram Radix Sanguisorbae 10-15 gram Pollen Typhae 10-20 gram
Rhizoma Cyperi 8-12 gram Carapax et Plastrum Testudinis 8-12 gram Cortex Ailanthi 10-20 gram
Fructus Mume 10-20 gram Radix Artemisia ordosicae 8-12 gram Fibra Trachycarpi 10-20 gram
Radix Angelicae Sinensis 10-15 gram Concha Ostreae 8-12 cron bone 8-12 gram
Colla Corii Asini 6-10 gram Cortex Lycii 8-12 gram Flos Chrysanthemi 8-12 gram
Radix Rehmanniae Preparata 8-12 gram Radix Panacis Quinquefolii 10-15 gram Radix Glycyrrhizae 8-12 gram
Rhizoma Atractylodis Macrocephalae 10-15 gram Poria 10-20 Keshan Fructus Corni 10-20 gram
Cortex Eucommiae 10-20 gram Radix Polygalae 10-20 gram Fructus Schisandrae Chinensis 10-16 gram
Cortex Moutan 8-12 gram Radix Bupleuri 10-15 gram Semen Plantaginis 8-16 gram
Radix Berchemiae Yunnanensis 12-20 gram Herba Commelinae 12-20 gram Cortex Phellodendri 8-10 gram
Wherein, be preferably
The Radix Codonopsis 12 gram Radixs Astragali 12 gram Radix Scutellariaes 12 grams
The Cortex Phellodendri 16 gram Radix Rehmanniae 16 gram Radix Paeoniae Albas 10 grams
Flos Sophorae 10 gram Radix Sanguisorbaes 12 gram Pollen Typhaes 16 grams
Rhizoma Cyperi 10 gram Carapax et Plastrum Testudiniss 10 gram Cortex Ailanthi 15 grams
Fructus Mume 15 gram Radix Artemisia ordosicae 10 gram Fibra Trachycarpis 15 grams
Radix Angelicae Sinensis 12 gram Concha Ostreaes 10 cron bones 10 grams
Colla Corii Asini 8 gram Cortex Lycii 10 gram Flos Chrysanthemis 10 grams
Radix Rehmanniae Preparata 10 gram Radix Panacis Quinquefoliis 12 gram Radix Glycyrrhizaes 10 grams
The Rhizoma Atractylodis Macrocephalae 12 gram Poria 15 Keshan Fructus Corni 15 grams
The Cortex Eucommiae 15 gram Radix Polygalaes 16 gram Fructus Schisandrae Chinensis 12 grams
Cortex Moutan 10 gram Radix Bupleuri 12 gram Semen Plantaginiss 10 grams
Radix Berchemiae Yunnanensis 15 gram Herba Commelinaes 15 gram Cortex Phellodendris 10 grams
The preparation method of medicine of the present invention is as follows
One, gets the raw materials ready
1, Radix Codonopsis: run through reed after cleaning silt, section or cutting are dried;
2, the Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through back section in time, dry;
3, Radix Scutellariae: choose decontamination, remove residual stem, soak into or put to soak slightly in the boiled water and pull out with cold water, running through the back section and drying (attention is avoided tanning by the sun excessively rubescent);
4, Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding are dried;
5, Radix Rehmanniae: remove impurity, clean, profit is cut sheet slightly, drying, and sieve removes chip;
6, the Radix Paeoniae Alba: choose decontamination, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;
7, charred Flos Sophorae: clean Flos Sophorae is gone in the pot, fry to coke black, sustainability is slightly sprayed clear water, and taking-up is dried;
8, Radix Sanguisorbae: choose decontamination, wash, soak slightly, run through, be cut into sheet, dry;
9, Pollen Tyjphae: rub broken caking, sieve, remove impurity;
10, Rhizoma Cyperi: choose decontamination, grind into particle, winnow with a dustpan fine, soft fur and smalls;
11, Carapax et Plastrum Testudinis: soak with clear water, scrape off residual meat, clean, dry the knock fritter;
12, fry Cortex Ailanthi: earlier wheat bran is sprinkled in the pot, heating to the cigarette time-out, is poured tree of heaven skin into again, stirs to the two sides coke yellow, takes out, and sieve removes wheat bran, cools 100 jin of every tree of heaven skins, 10 jin in wheat bran;
13, carbonized Fructus Mume: get clean Fructus Mume, fry with high heat to skin and flesh and heave, shrivelled speckle occurs and be degree, water spray dries, and takes out, and cools;
14, Radix Artemisia ordosicae: choose decontamination, clean, cutting is dried;
15, charred Petiolus Trachycarpi: get clean Fibra Trachycarpi, put in the pot, cover the slightly little pot of a bore, paste a piece of paper on the pot, sternly seal with yellow mud in two pots of joints, low baking temperature is forged to blank sheet of paper and is coke yellow, ceases fire, and Hou Leng takes out;
16, Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening dries in the air when suitable to inside and outside humidity slightly, and section is dried;
17, Concha Ostreae: clean, dry, pulverize usefulness;
18, Os Draconis: outwash earth, smash;
19, Colla Corii Asini: smash usefulness to pieces;
20, Cortex Lycii: choose decontamination and core, slightly wash, dry, cutting;
21, Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;
22, Radix Rehmanniae Preparata: select clean Radix Rehmanniae Preparata to get final product;
23, Radix Panacis Quinquefolii: former medicinal clear water spray tide, cover wet cloth, Xia Qiu profit 2 days, Winter-Spring profit 3 days is taken out section, dries;
24, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when saturating to eighty per cant, pull out, run through section, airing;
25, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out behind the bubble, run through, section is dried;
26, Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;
27, Fructus Corni: clean, except removal core and impurity, dry;
28, the Cortex Eucommiae: remove rough bark, clean, run through, dice or strand dry;
29, Radix Polygalae: choose decontamination, cutting, sieve dedust bits;
30, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in the food steamer and steam thoroughly, taking-up is dried;
31, Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;
32, Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through back section in time, dry immediately;
33, Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
34, Radix Berchemiae Yunnanensis: the 9-10 month is excavated its root, cleans, and runs through, and section is dried;
35, Herba Commelinae: choose decontamination, clean, section is dried;
36, Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding are dried.
Two, preparation
1, Radix Codonopsis with described weight, the Radix Astragali, Radix Scutellariae, Cortex Phellodendri, Radix Rehmanniae, the Radix Paeoniae Alba, Flos Sophorae, Radix Sanguisorbae, Pollen Typhae, Rhizoma Cyperi, Carapax et Plastrum Testudinis, Cortex Ailanthi, Fructus Mume, Radix Artemisia ordosicae, Fibra Trachycarpi, Radix Angelicae Sinensis, Concha Ostreae, Os Draconis, Colla Corii Asini, Cortex Lycii, Flos Chrysanthemi, Radix Rehmanniae Preparata, Radix Panacis Quinquefolii, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Poria, Fructus Corni, the Cortex Eucommiae, Radix Polygalae, Fructus Schisandrae Chinensis, Cortex Moutan, Radix Bupleuri, Semen Plantaginis, Radix Berchemiae Yunnanensis, Herba Commelinae, Cortex Phellodendri decocts with water, add for the first time 6 times of amounts of water, soaked 180 minutes, intense fire decocts boiling 20 minutes, reuse slow fire boiling 25 minutes, filter time decoction liquor of winning.
2, the medicinal residues that will filter for the first time add 3 times of amounts of water, and intense fire boils, and reuse slow fire boiling 20 minutes is filtered, and get decoction liquor for the second time.
3, twice decoction liquor merged, intense fire boils, and simmers in water 20 minutes again, takes out, and is divided into 4 doses.
Medicine of the present invention has QI invigorating and consolidates, clearing away heat and cooling blood, and blood circulation promoting and blood stasis dispelling, the function that hemostasis is taken off admittedly, treatment dysfunctional uterine bleeding instant effect does not recur the cure rate height.
Below further set forth the beneficial effect of medicine of the present invention by testing example, these tests comprise that the animal toxicity test of medicine of the present invention and clinical observation test.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 20 of rabbit, the male and female dual-purpose, body weight 2.0-2.5kg divides two groups, and 10 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 30ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, serve on 7 days every day twice, observes administration reaction every day, and the result shows that two groups of rabbit activities, diet are normal, and medicine does not have bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 160 examples for medical treatment, 20-30 years old age, 35 examples, 30-40 years old 85 example, 40-50 years old 40 example.
2, diagnostic criteria
The women is the acute disease of heavy vaginal bleeding not in menstrual period and suddenly.
3, Therapeutic Method
Select above-mentioned medicament for use, take to the patient, take 1 dose at every turn, every day is early, middle and late respectively obeys 1 time, and 20 days is a course for the treatment of, takes two courses for the treatment of continuously.
4, efficacy assessment standard
Produce effects: treatment back clinical symptom disappearance, it is normal that body constitution is recovered, and observes and do not have the recidivist half a year;
Take a turn for the better: clinical symptoms is obviously improved, and body constitution is progressively recovered;
Invalid: clinical partial symptoms disappears or does not have change, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, with Drug therapy dysfunctional uterine bleeding patient 160 examples of the present invention, produce effects 152 examples as a result, obvious effective rate is 95%, 5 examples that take a turn for the better, improvement rate is 3.13%, invalid 3 examples, total effective rate is 98.13%.
Claims (3)
1. medicine for the treatment of dysfunctional uterine bleeding, it is characterized in that: it is to be made by the crude drug in the following weight range:
Radix Codonopsis 10-15 gram Radix Astragali 10-15 gram Radix Scutellariae 10-15 gram
Cortex Phellodendri 15-20 gram Radix Rehmanniae 10-20 gram Radix Paeoniae Alba 8-12 gram
Flos Sophorae 8-12 gram Radix Sanguisorbae 10-15 gram Pollen Typhae 10-20 gram
Rhizoma Cyperi 8-12 gram Carapax et Plastrum Testudinis 8-12 gram Cortex Ailanthi 10-20 gram
Fructus Mume 10-20 gram Radix Artemisia ordosicae 8-12 gram Fibra Trachycarpi 10-20 gram
Radix Angelicae Sinensis 10-15 gram Concha Ostreae 8-12 cron bone 8-12 gram
Colla Corii Asini 6-10 gram Cortex Lycii 8-12 gram Flos Chrysanthemi 8-12 gram
Radix Rehmanniae Preparata 8-12 gram Radix Panacis Quinquefolii 10-15 gram Radix Glycyrrhizae 8-12 gram
Rhizoma Atractylodis Macrocephalae 10-15 gram Poria 10-20 Keshan Fructus Corni 10-20 gram
Cortex Eucommiae 10-20 gram Radix Polygalae 10-20 gram Fructus Schisandrae Chinensis 10-16 gram
Cortex Moutan 8-12 gram Radix Bupleuri 10-15 gram Semen Plantaginis 8-16 gram
Radix Berchemiae Yunnanensis 12-20 gram Herba Commelinae 12-20 gram Cortex Phellodendri 8-10 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
The Radix Codonopsis 12 gram Radixs Astragali 12 gram Radix Scutellariaes 12 grams
The Cortex Phellodendri 16 gram Radix Rehmanniae 16 gram Radix Paeoniae Albas 10 grams
Flos Sophorae 10 gram Radix Sanguisorbaes 12 gram Pollen Typhaes 16 grams
Rhizoma Cyperi 10 gram Carapax et Plastrum Testudiniss 10 gram Cortex Ailanthi 15 grams
Fructus Mume 15 gram Radix Artemisia ordosicae 10 gram Fibra Trachycarpis 15 grams
Radix Angelicae Sinensis 12 gram Concha Ostreaes 10 cron bones 10 grams
Colla Corii Asini 8 gram Cortex Lycii 10 gram Flos Chrysanthemis 10 grams
Radix Rehmanniae Preparata 10 gram Radix Panacis Quinquefoliis 12 gram Radix Glycyrrhizaes 10 grams
The Rhizoma Atractylodis Macrocephalae 12 gram Poria 15 Keshan Fructus Corni 15 grams
The Cortex Eucommiae 15 gram Radix Polygalaes 16 gram Fructus Schisandrae Chinensis 12 grams
Cortex Moutan 10 gram Radix Bupleuri 12 gram Semen Plantaginiss 10 grams
Radix Berchemiae Yunnanensis 15 gram Herba Commelinaes 15 gram Cortex Phellodendris 10 grams.
3. according to the preparation method of claim 1 or 2 described medicines, it comprises the following steps:
(1) gets the raw materials ready
(1) Radix Codonopsis: run through reed after cleaning silt, section or cutting are dried;
(2) Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through back section in time, dry;
(3) Radix Scutellariae: choose decontamination, remove residual stem, soak into or put to soak slightly in the boiled water and pull out with cold water, running through the back section and drying (attention is avoided tanning by the sun excessively rubescent);
(4) Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding are dried;
(5) Radix Rehmanniae: remove impurity, clean, profit is cut sheet slightly, drying, and sieve removes chip;
(6) Radix Paeoniae Alba: choose decontamination, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;
(7) charred Flos Sophorae: clean Flos Sophorae is gone in the pot, fry to coke black, sustainability is slightly sprayed clear water, and taking-up is dried;
(8) Radix Sanguisorbae: choose decontamination, wash, soak slightly, run through, be cut into sheet, dry;
(9) Pollen Tyjphae: rub broken caking, sieve, remove impurity;
(10) Rhizoma Cyperi: choose decontamination, grind into particle, winnow with a dustpan fine, soft fur and smalls;
(11) Carapax et Plastrum Testudinis: soak with clear water, scrape off residual meat, clean, dry the knock fritter;
(12) fry Cortex Ailanthi: earlier wheat bran is sprinkled in the pot, heating to the cigarette time-out, is poured tree of heaven skin into again, stirs to the two sides coke yellow, takes out, and sieve removes wheat bran, cools 100 jin of every tree of heaven skins, 10 jin in wheat bran;
(13) carbonized Fructus Mume: get clean Fructus Mume, fry with high heat to skin and flesh and heave, shrivelled speckle occurs and be degree, water spray dries, and takes out, and cools;
(14) Radix Artemisia ordosicae: choose decontamination, clean, cutting is dried;
(15) charred Petiolus Trachycarpi: get clean Fibra Trachycarpi, put in the pot, cover the slightly little pot of a bore, paste a piece of paper on the pot, sternly seal with yellow mud in two pots of joints, low baking temperature is forged to blank sheet of paper and is coke yellow, ceases fire, and Hou Leng takes out;
(16) Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening dries in the air when suitable to inside and outside humidity slightly, and section is dried;
(17) Concha Ostreae: clean, dry, pulverize usefulness;
(18) Os Draconis: outwash earth, smash;
(19) Colla Corii Asini: smash usefulness to pieces;
(20) Cortex Lycii: choose decontamination and core, slightly wash, dry, cutting;
(21) Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;
(22) Radix Rehmanniae Preparata: select clean Radix Rehmanniae Preparata to get final product;
(23) Radix Panacis Quinquefolii: former medicinal clear water spray tide, cover wet cloth, Xia Qiu profit 2 days, Winter-Spring profit 3 days is taken out section, dries;
(24) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when saturating to eighty per cant, pull out, run through section, airing;
(25) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out behind the bubble, run through, section is dried;
(26) Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;
(27) Fructus Corni: clean, except removal core and impurity, dry;
(28) Cortex Eucommiae: remove rough bark, clean, run through, dice or strand dry;
(29) Radix Polygalae: choose decontamination, cutting, sieve dedust bits;
(30) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in the food steamer and steam thoroughly, taking-up is dried;
(31) Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;
(32) Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through back section in time, dry immediately;
(33) Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
(34) Radix Berchemiae Yunnanensis: the 9-10 month is excavated its root, cleans, and runs through, and section is dried;
(35) Herba Commelinae: choose decontamination, clean, section is dried;
(36) Cortex Phellodendri: choose decontamination, wash, pull out, run through, section or shredding are dried;
(2) preparation
(1) with the Radix Codonopsis of described weight, the Radix Astragali, Radix Scutellariae, Cortex Phellodendri, Radix Rehmanniae, the Radix Paeoniae Alba, Flos Sophorae, Radix Sanguisorbae, Pollen Typhae, Rhizoma Cyperi, Carapax et Plastrum Testudinis, Cortex Ailanthi, Fructus Mume, Radix Artemisia ordosicae, Fibra Trachycarpi, Radix Angelicae Sinensis, Concha Ostreae, Os Draconis, Colla Corii Asini, Cortex Lycii, Flos Chrysanthemi, Radix Rehmanniae Preparata, Radix Panacis Quinquefolii, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Poria, Fructus Corni, the Cortex Eucommiae, Radix Polygalae, Fructus Schisandrae Chinensis, Cortex Moutan, Radix Bupleuri, Semen Plantaginis, Radix Berchemiae Yunnanensis, Herba Commelinae, Cortex Phellodendri decocts with water, add for the first time 6 times of amounts of water, soaked 180 minutes, intense fire decocts boiling 20 minutes, reuse slow fire boiling 25 minutes, filter time decoction liquor of winning;
(2) medicinal residues that will filter for the first time add 3 times of amounts of water, and intense fire boils, and reuse slow fire boiling 20 minutes is filtered, and get decoction liquor for the second time;
(3) twice decoction liquor merged, intense fire boils, and simmers in water 20 minutes again, takes out, and is divided into 4 doses.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104096056A (en) * | 2014-04-21 | 2014-10-15 | 马家庆 | Traditional Chinese medicine for treatment of dysfunctional uterine bleeding of pattern of insecurity of the thoroughfare and controlling vessels |
| CN105056290A (en) * | 2015-08-26 | 2015-11-18 | 东莞市达庆医疗器械有限公司 | Medical biological hydrogel functional dressing and preparing method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101502634A (en) * | 2009-03-06 | 2009-08-12 | 陈殿红 | Chinese medicinal composition for treating uterine blood flow and preparation method thereof |
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| CN101502634A (en) * | 2009-03-06 | 2009-08-12 | 陈殿红 | Chinese medicinal composition for treating uterine blood flow and preparation method thereof |
Non-Patent Citations (2)
| Title |
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| 廖莫名: "功能性子宫出血的中医辨证用药", 《光明中医》, vol. 16, no. 93, 31 December 2001 (2001-12-31), pages 23 - 25 * |
| 鹿鸣瑞等: "中医药治疗功能性子宫出血的研究进展", 《中国民间疗法》, vol. 13, no. 10, 31 October 2005 (2005-10-31), pages 62 - 64 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104096056A (en) * | 2014-04-21 | 2014-10-15 | 马家庆 | Traditional Chinese medicine for treatment of dysfunctional uterine bleeding of pattern of insecurity of the thoroughfare and controlling vessels |
| CN105056290A (en) * | 2015-08-26 | 2015-11-18 | 东莞市达庆医疗器械有限公司 | Medical biological hydrogel functional dressing and preparing method thereof |
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