CN103251805A - Externally-applied pharmaceutical composition for treating dermatopathy - Google Patents
Externally-applied pharmaceutical composition for treating dermatopathy Download PDFInfo
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Abstract
The invention discloses an externally-applied medicinal preparation for treating or alleviating dermatopathy. The medicinal preparation is composed of traditional Chinese medicines such as rhubarb root, hydnocarpus seeds and the like, and can be made into various externally-applied dosage forms according to clinic needs. The pharmaceutical composition has very excellent effect of treating or alleviating dermatopathy, especially pachyderma keratosic dermatosis.
Description
Technical field
The invention discloses a kind of dermopathic external medicine preparation for the treatment of or alleviate, formed by Chinese medicines such as Radix Rumicis, Semen Hydnocarpis, can be prepared into various exterior-applied formulations according to clinical needs.This pharmaceutical composition has very excellent treatment or mitigation for the especially plump keratinization dermatoses of dermatosis.
Background technology
Dermatosis is one of the commonly encountered diseases that has a strong impact on people ' s health, frequently-occurring disease, after referring to that skin (comprising hair and first) is subjected to the influence of internal and external factor, its form, 26S Proteasome Structure and Function all change, and produce pathological process, and produce various clinical priority performances accordingly.The common skin disease has psoriasis (psoriasis), vitiligo, rosacea, impetigo, the infection of suppuration bacterium, cicatrix, tinea, ichthyosis, bromhidrosis, comedo, folliculitis, alopecia areata, alopecia, clavus, freckle, pompholyx, acarid dermatitis, eczema, urticaria, tinea unguium, scleroderma, skin pruritus, depilation, chloasma etc.Because most dermopathic definite pathogenic factors are unclear as yet, treating for skin disease all can only the respite symptom at present, can't effect a radical cure or prevent recurrence.It is feature with epidermal hyperplasia plumpness, hyperkeratosis that one class disease is arranged in the dermatosis, is referred to as plump keratinization dermatoses, for example clavus, stubborn dermatitis mass in the abdomen, tinea unguium, various tinea, kerf disease and callosity etc.
Wherein, clavus is that shape such as cone embed Intradermal owing to the friction that is squeezed of the long-term antibody of local skin causes the horny layer of hypertrophy, and the pinnacle is charged in the corium, and in case the pressuring nerve tip is part pressurized or be subjected to squeeze and will cause tangible pain.The end of circular cone is a circle at skin surface, or oval, the speckle that yellowish chromaticness is hard, and boundary is clear general as the Semen Glycines size.Because adult's quantity of motion is big, so be mainly in person between twenty and fifty.Someone thinks that clavus is taken place relevant with infected by microbes, because with the bedroom student cross infection phenomenon is arranged.Treatment clavus is generally applied ointment or plaster with corn plaster, and corn plaster is the principle that adopts the carbolic acid corrosion, all will carry out the corrosion layer cleaning every day, wastes time and energy, and the patient is difficult to adhere to, so effect is bad.Also have report to adopt the absolute alcohol treatment, absolute alcohol makes cell dehydration, sclerosis, necrosis, and method is simple, and is easy to operate, but needs strict control ethanol dosage, otherwise causes necrosis, liquefaction or suppuration easily.The operative treatment determined curative effect, but be reluctant to accept this Therapeutic Method because the patient is frightened.
In addition, tinea manus and pedis is the general name of the tinea manuum and tinea pedis.The tinea manuum refer to occur in palm and refer between dermatophytosis infect.The dermatophytosis that tinea pedis refers to betide between sufficient sole of the foot portion and toe infects.Tinea pedis is modal disease in the tinea, is more common in the adult, and the whole world is popular.In tinea pedis morbidity, lacking sebaceous gland and wearing the moist environment that the closure shoes cause is most important factor.Main pathogenic bacterium comprise trichophyton, alpha fungus, acrothesium floccosum, trichophyton.Tinea pedis seldom causes serious disease or death, but can be used as the door of bacterial invasion and cause bacillary cellulitis, and the type tinea pedis has high risk between toe, and tinea unguium secondly is sufficient sole of the foot portion tinea pedis again.Tinea unguium is modal a kind of tinea unguium in the daily life, is called tinea unguium, tinea unguium again.Be the first illness of normal trouble, account for the more than half of onychonosus.The finger toenail all can be fallen ill, and toenail is easier to be suffered from.The ratio that tinea unguium appears in the adult is about 6-8%.
Because the brothers outside dermatosis has a strong impact on and is exposed to are attractive in appearance, and very obstinate, influence very much patient's life with self-confident.Therefore and sx doctor trained in Western medicine generally adopts chemotherapys such as immunosuppressant or corticosteroid hormone to this disease, therapeutic effect is relatively poor, and drug withdrawal easily recurs, even.The traditional Chinese medical science it is generally acknowledged that dermopathic pathogenesis is that the heat in blood poison is contained, and asthenia of qi and blood wind-dryness etc. causes that it is also more with prescription that reported in literature is treated this sick method for the treatment of, but also mostly be interim relief of symptoms, and need take medicine for a long time.
Summary of the invention
The invention provides a kind of externally-applied medicinal composition, can effectively alleviate even effect a radical cure dermatosis.The present invention is better for the therapeutic effect of plump keratinization dermatoses.
This pharmaceutical composition is made by following components in weight percentage: Radix Rumicis 30-120 part, Semen Hydnocarpi 30-120 part, Caulis Impatientis 10-70 part, Fructus Bruceae 10-70 part, Nidus Vespae 10-70 part, bright Flos Impatientis 10-70 part, Sal Ammoniacus 40-250 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 100-650 part, Resina garciniae (system) 50-350 part.
Preferred pharmaceutical composition is made by following components in weight percentage: Radix Rumicis 45-90 part, Semen Hydnocarpi 45-90 part, Caulis Impatientis 20-50 part, Fructus Bruceae 20-50 part, Nidus Vespae 20-50 part, bright Flos Impatientis 20-50 part, Sal Ammoniacus 70-180 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 220-500 part, Resina garciniae (system) 120-150 part.
Most preferred pharmaceutical composition is made by following components in weight percentage: 60 parts of Radix Rumiciss, 60 parts of Semen Hydnocarpis, 30 parts of Caulis Impatientiss, 30 parts of Fructus Bruceaes, 30 parts of Nidus Vespaes, 30 parts of bright Flos Impatientiss, 120 parts of Sal Ammoniacus, 350 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 1 part of Resina garciniae (system).
In addition, on the basis of aforementioned pharmaceutical compositions, can also increase following arbitrary class or two class Chinese medicine compositions as one sees fit.One class is promoting blood circulation to remove obstruction in the collateral, wind-expelling pain-stopping class Chinese medicine, especially any one or more components in animal or the insects Chinese medicine namely can increase any one or more components of following weight proportioning: Scolopendra 5-40 part, Mylabris (system) 5-40 part, Squama Manis (system) 5-40 part, Scorpio 5-40 part on above-mentioned prescription basis; The preferred weight proportioning of described increase component is: 15 parts of Scolopendras, 15 parts of Mylabris (system), 15 parts of Squama Maniss (system), 15 parts of Scorpios.Another kind of is expelling wind and removing dampness, antalgic class Chinese medicine, namely can increase any one or more components of following weight proportioning on pharmaceutical composition mentioned above basis: Flos Rhododendri Mollis 10-50 part, Radix Aconiti (system) 5-30 part, Radix Aconiti Kusnezoffii (system) 5-30 part, Semen Strychni (system) 10-50 part; The preferred weight proportioning of described increase component is: 30 parts of Flos Rhododendri Mollis, 15 parts of Radix Aconitis (system), 15 parts of Radix Aconiti Kusnezoffii (system), 30 parts of Semen Strychni (system).
Secondly, on the basis of aforementioned pharmaceutical compositions, can also increase following any one or more Chinese medicine compositions as one sees fit, namely increase any one or more Chinese medicine components of following weight proportion: Spina Gleditsiae 10-70 part, Radix Stemonae 10-70 part, Semen Ginkgo 10-70 part, Semen Armeniacae Amarum 10-70 part; Preferred weight proportion is: 30 parts of Spina Gleditsiaes, 30 parts of the Radixs Stemonae, 30 parts of Semen Ginkgoes, 30 parts of Semen Armeniacae Amarums.
Again, in the preparation process of aforementioned pharmaceutical compositions, any one or two kinds of components of following weight proportion can also be added, drug effect can be promoted, as follows: Calomelas 50-350 part, Plumbum preparatium 1000-3500 part; Preferred weight proportion is: 170 parts of Calomelass, 2700 parts of Plumbum preparatium.
In addition, according to the dialectical difference of individual patients, can also carry out some flexible adjustment to above-mentioned prescription, include but not limited to: increase or alleviate part or all of prescription consumption; Delete the part component; Increase or replace some invigorating blood circulation heavily fortified points, detoxicating and resolving stagnation of pathogens, killing parasites for relieving itching, removing blood stasis to promote tissue regeneration Chinese medicine.Undoubtedly, these adjustment all should be included within the present invention.
Pharmaceutical composition of the present invention can be prepared as various exterior-applied formulations, include but not limited to following dosage form: unguentum, liniment, solution, sublimed preparation, ointment, ointment, patch, oil preparation, lotion, gel, liniment and cream all have clinical effectiveness preferably.
Wherein, the preferred dosage form of pharmaceutical composition of the present invention is unguentum, and preparation method is comparatively simple, taking convenience, and utilization ratio of drug is higher.Its preparation method may further comprise the steps:
Sal Ammoniacus, Pseudobulbus Bletillae (Rhizoma Bletillae), goa powder are broken into fine powder, and be standby.It is fried withered with putting in the pot with Oleum Sesami and Oleum Verniciae fordii that all the other flavour of a drug are pulverized the back, removes slag, and continues the high temperature heating, makes medicine oil.Other gets Colophonium and a few flavor medicated powder of above-mentioned Sal Ammoniacus add in the oil, stirs evenly, and receives cream.Cream was soaked in the cold water seven days, again with the cream heat fused to proper temperature, be twisted into strip, namely.During use plaster heated softening after, spread out on cloth or ground paper external application affected part or plaster heated directly spread on the affected part after softening.
Content of the present invention also comprises this pharmaceutical composition in preparation treatment or improves application in the dermopathic medicine, is preferably the preparation treatment or alleviates application in the medicine of plump keratinization dermatoses.
The present invention is described further by the following examples.
The specific embodiment
Embodiment 1
Prescription: Radix Rumicis 30g, Semen Hydnocarpi 45g, Caulis Impatientis 30g, Fructus Bruceae 30g, Nidus Vespae 50g, bright Flos Impatientis 50g, Sal Ammoniacus 180g, Pseudobulbus Bletillae (Rhizoma Bletillae) 500g, Resina garciniae (system) 350g.
Method for making and use: Sal Ammoniacus, Pseudobulbus Bletillae (Rhizoma Bletillae), goa powder are broken into fine powder, and be standby.It is fried withered with putting in the pot with Oleum Sesami and Oleum Verniciae fordii that all the other flavour of a drug are pulverized the back, removes slag, and continues the high temperature heating, makes medicine oil.Other gets Colophonium and a few flavor medicated powder of above-mentioned Sal Ammoniacus add in the oil, stirs evenly, and receives cream.Cream was soaked in the cold water seven days, again with the cream heat fused to proper temperature, be twisted into strip, namely.During use plaster heated softening after, spread out on cloth or ground paper external application affected part or plaster heated directly spread on the affected part after softening.
Embodiment 2
Prescription: Radix Rumicis 45g, Semen Hydnocarpi 60g, Caulis Impatientis 20g, Fructus Bruceae 20g, Nidus Vespae 20g, bright Flos Impatientis 30g, Sal Ammoniacus 120g, Pseudobulbus Bletillae (Rhizoma Bletillae) 220g, Resina garciniae (system) 50g.
Method for making and use: with embodiment 1.
Embodiment 3
Prescription: Radix Rumicis 120g, Semen Hydnocarpi 120g, Caulis Impatientis 50g, Fructus Bruceae 10g, Nidus Vespae 70g, bright Flos Impatientis 20g, Sal Ammoniacus 40g, Pseudobulbus Bletillae (Rhizoma Bletillae) 100g, Resina garciniae (system) 120g.
Method for making and use: with embodiment 1.
Embodiment 4
Prescription: Radix Rumicis 60g, Semen Hydnocarpi 90g, Caulis Impatientis 10g, Fructus Bruceae 70g, Nidus Vespae 10g, bright Flos Impatientis 10g, Sal Ammoniacus 70g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g, Resina garciniae (system) 250g.
Method for making and use: with embodiment 1.
Embodiment 5
Prescription: Radix Rumicis 90g, Semen Hydnocarpi 30g, Caulis Impatientis 70g, Fructus Bruceae 50g, Nidus Vespae 30g, bright Flos Impatientis 70g, Sal Ammoniacus 250g, Pseudobulbus Bletillae (Rhizoma Bletillae) 650g, Resina garciniae (system) 170g.
Method for making and use: with embodiment 1.
Embodiment 6
Prescription: Radix Rumicis 60g, Semen Hydnocarpi 60g, Caulis Impatientis 30g, Fructus Bruceae 30g, Nidus Vespae 30g, bright Flos Impatientis 30g, Sal Ammoniacus 120g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g, Resina garciniae (system) 170g.
Method for making and use: with embodiment 1.
Embodiment 7
Prescription: Radix Rumicis 30g, Semen Hydnocarpi 45g, Caulis Impatientis 30g, Fructus Bruceae 50g, Nidus Vespae 70g, bright Flos Impatientis 30g, Sal Ammoniacus g120, Pseudobulbus Bletillae (Rhizoma Bletillae) 220g, Resina garciniae (system) 50g, Scolopendra 15g, Squama Manis (system) 40g, Scorpio 15g.
Method for making and use: with embodiment 1.
Embodiment 8
Prescription: Radix Rumicis 45g, Semen Hydnocarpi 60g, Caulis Impatientis 50g, Fructus Bruceae 70g, Nidus Vespae 10g, bright Flos Impatientis 10g, Sal Ammoniacus 180g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g, Resina garciniae (system) 350g, Scolopendra 5g, Mylabris (system) 40g, Squama Manis (system) 5g, Scorpio 5g.
Method for making and use: with embodiment 1.
Embodiment 9
Prescription: Radix Rumicis 60g, Semen Hydnocarpi 90g, Caulis Impatientis 70g, Fructus Bruceae 10g, Nidus Vespae 20g, bright Flos Impatientis 20g, Sal Ammoniacus 250g, Pseudobulbus Bletillae (Rhizoma Bletillae) 100g, Resina garciniae (system) 170g, Scolopendra 40g, Mylabris (system) 5g, Squama Manis (system) 15g.
Method for making and use: with embodiment 1.
Embodiment 10
Prescription: Radix Rumicis 90g, Semen Hydnocarpi 120g, Caulis Impatientis 10g, Fructus Bruceae 20g, Nidus Vespae 30g, bright Flos Impatientis 50g, Sal Ammoniacus 70g, Pseudobulbus Bletillae (Rhizoma Bletillae) 650g, Resina garciniae (system) 120g, Scorpio 40g.
Method for making and use: with embodiment 1.
Embodiment 11
Prescription: Radix Rumicis 120g, Semen Hydnocarpi 30g, Caulis Impatientis 20g, Fructus Bruceae 30g, Nidus Vespae 50g, bright Flos Impatientis 70g, Sal Ammoniacus 40g, Pseudobulbus Bletillae (Rhizoma Bletillae) 500g, Resina garciniae (system) 250g, Mylabris (system) 15g.
Method for making and use: with embodiment 1.
Embodiment 12
Prescription: Radix Rumicis 30g, Semen Hydnocarpi 45g, Caulis Impatientis 30g, Fructus Bruceae 30g, Nidus Vespae 50g, bright Flos Impatientis 50g, Sal Ammoniacus 180g, Pseudobulbus Bletillae (Rhizoma Bletillae) 500g, Resina garciniae (system) 350g, Squama Manis (system) 15.
Method for making and use: with embodiment 1.
Embodiment 13
Prescription: Radix Rumicis 45g, Semen Hydnocarpi 60g, Caulis Impatientis 20g, Fructus Bruceae 20g, Nidus Vespae 20g, bright Flos Impatientis 30g, Sal Ammoniacus 120g, Pseudobulbus Bletillae (Rhizoma Bletillae) 220g, Resina garciniae (system) 50g, Flos Rhododendri Mollis 30g.
Method for making and use: with embodiment 1.
Embodiment 14
Prescription: Radix Rumicis 120g, Semen Hydnocarpi 120g, Caulis Impatientis 50g, Fructus Bruceae 10g, Nidus Vespae 70g, bright Flos Impatientis 20g, Sal Ammoniacus 40g, Pseudobulbus Bletillae (Rhizoma Bletillae) 100g, Resina garciniae (system) 120g, Flos Rhododendri Mollis 50g, Semen Strychni (system) 10g.
Method for making and use: with embodiment 1.
Embodiment 15
Prescription: Radix Rumicis 60g, Semen Hydnocarpi 90g, Caulis Impatientis 10g, Fructus Bruceae 70g, Nidus Vespae 10g, bright Flos Impatientis 10g, Sal Ammoniacus 70g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g, Resina garciniae (system) 250g, Radix Aconiti (system) 30g, Radix Aconiti Kusnezoffii (system) 30g, Semen Strychni (system) 30g.
Method for making and use: with embodiment 1.
Embodiment 16
Prescription: Radix Rumicis 90g, Semen Hydnocarpi 30g, Caulis Impatientis 70g, Fructus Bruceae 50g, Nidus Vespae 30g, bright Flos Impatientis 70g, Sal Ammoniacus 250g, Pseudobulbus Bletillae (Rhizoma Bletillae) 650g, Resina garciniae (system) 170g, Flos Rhododendri Mollis 10g, Radix Aconiti (system) 5g, Semen Strychni (system) 50g.
Method for making and use: with embodiment 1.
Embodiment 17
Prescription: Radix Rumicis 60g, Semen Hydnocarpi 60g, Caulis Impatientis 30g, Fructus Bruceae 30g, Nidus Vespae 30g, bright Flos Impatientis 30g, Sal Ammoniacus 120g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g, Resina garciniae (system) 170g, Radix Aconiti Kusnezoffii (system) 15g.
Method for making and use: with embodiment 1.
Embodiment 18
Prescription: Radix Rumicis 45g, Semen Hydnocarpi 60g, Caulis Impatientis 20g, Fructus Bruceae 20g, Nidus Vespae 20g, bright Flos Impatientis 30g, Sal Ammoniacus 120g, Pseudobulbus Bletillae (Rhizoma Bletillae) 220g, Resina garciniae (system) 50g, Radix Aconiti (system) 15g.
Method for making and use: with embodiment 1.
Embodiment 19
Prescription: Radix Rumicis 120g, Semen Hydnocarpi 120g, Caulis Impatientis 50g, Fructus Bruceae 10g, Nidus Vespae 70g, bright Flos Impatientis 20g, Sal Ammoniacus 40g, Pseudobulbus Bletillae (Rhizoma Bletillae) 100g, Resina garciniae (system) 120g, Scolopendra 15g, Mylabris (system) 15g, Squama Manis (system) 15g, Scorpio 15g, Flos Rhododendri Mollis 30g, Radix Aconiti (system) 15g, Radix Aconiti Kusnezoffii (system) 15g, Semen Strychni (system) 30g.
Method for making and use: with embodiment 1.
Embodiment 20
Prescription: Radix Rumicis 60g, Semen Hydnocarpi 90g, Caulis Impatientis 10g, Fructus Bruceae 70g, Nidus Vespae 10g, bright Flos Impatientis 10g, Sal Ammoniacus 70g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g, Resina garciniae (system) 250g, Scolopendra 5g, Mylabris (system) 40g, Squama Manis (system) 15g, Scorpio 40g, Flos Rhododendri Mollis 10g, Radix Aconiti (system) 5g, Radix Aconiti Kusnezoffii (system) 5g, Semen Strychni (system) 10g, Calomelas 50g, Plumbum preparatium 3500g.
Method for making and use: Sal Ammoniacus, Pseudobulbus Bletillae (Rhizoma Bletillae), Resina garciniae, easily be ground into fine powder, standby.All the other flavour of a drug are pulverized the back except Plumbum preparatium fried withered with putting in the pot with Oleum Sesami and Oleum Verniciae fordii, removes slag, and continues the high temperature heating, makes medicine oil.Other gets in a few flavor medicated powder adding of Plumbum preparatium, Colophonium and above-mentioned Sal Ammoniacus oil, stirs evenly, and receives cream.Cream was soaked in the cold water seven days, again with the cream heat fused to proper temperature, be twisted into strip, namely.During use plaster heated softening after, spread out on cloth or ground paper external application affected part or plaster heated directly spread on the affected part after softening.
Embodiment 21
Prescription: Radix Rumicis 90g, Semen Hydnocarpi 30g, Caulis Impatientis 70g, Fructus Bruceae 50g, Nidus Vespae 30g, bright Flos Impatientis 70g, Sal Ammoniacus 250g, Pseudobulbus Bletillae (Rhizoma Bletillae) 650g, Resina garciniae (system) 170g, Scolopendra 40g, Mylabris (system) 5g, Squama Manis (system) 5g, Scorpio 5g, Flos Rhododendri Mollis 50g, Radix Aconiti (system) 30g, Radix Aconiti Kusnezoffii (system) 30g, Semen Strychni (system) 50g, Spina Gleditsiae 30g, Radix Stemonae 30g, Semen Armeniacae Amarum 30g, Calomelas 350g, Plumbum preparatium 1000g.
Method for making and use: Sal Ammoniacus, Pseudobulbus Bletillae (Rhizoma Bletillae), goa powder are broken into fine powder, and be standby.It is fried withered with putting in the pot with Oleum Sesami and Oleum Verniciae fordii that all the other flavour of a drug are pulverized the back, removes slag, and continues the high temperature heating, makes medicine oil.Other gets Colophonium and a few flavor medicated powder of above-mentioned Sal Ammoniacus add in the oil, adds certain water gaging, and heating stirs evenly, and obtains washing liquid, is used for flushing and the dipping in affected part.
Embodiment 22
Prescription: Radix Rumicis 60g, Semen Hydnocarpi 60g, Caulis Impatientis 30g, Fructus Bruceae 30g, Nidus Vespae 30g, bright Flos Impatientis 30g, Sal Ammoniacus 120g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g, Resina garciniae (system) 170g, Scolopendra 15g, Mylabris (system) 15g, Squama Manis (system) 40g, Scorpio 15g, Flos Rhododendri Mollis 30g, Radix Aconiti (system) 15g, Radix Aconiti Kusnezoffii (system) 15g, Semen Strychni (system) 30g, Spina Gleditsiae 30g, Semen Ginkgo 30g, Calomelas 170g, Plumbum preparatium 2700g.
Method for making and use: with embodiment 20.
Embodiment 23
The present invention has carried out clinical observation on the therapeutic effect to the pharmaceutical composition for preparing among above-described embodiment 1-22, and the result shows that the present invention has very excellent therapeutic effect to plump keratinization dermatoses.
1, preparation of the present invention is to the clinical observation on the therapeutic effect of clavus
526 routine patients are divided into 23 groups.Wherein, male 320 examples, women 206 examples, 20～70 years old age, average 35 years old.Diagnostic criteria is determined diagnosis with reference to " modern dermiatrics ".Earlier with affected part with hot-water soak, scrape off the horny layer of epidermis with cutter, matched group adopts the corn plaster treatment then, all the other treatment groups adopt the preparation among embodiment 1-22 directly to be attached to affected part or foot bath.
Curative effect determinate standard:
Clinical cure: local pain, scleroma disappear substantially.
Take a turn for the better: local pain obviously alleviates, and the scleroma maximum gauge dwindles more than 1/2.
Invalid: local pain does not subtract, and the scleroma maximum gauge does not dwindle, or treatment improvement recurrence again after 1 month.
Total effective rate=(clinical cure+improvement)/n * 100%.
2, preparation of the present invention is to the observation of curative effect of other plump keratinization dermatoses
For many years, adopt the preparation in the embodiment of the invention, plump keratinization dermatoses such as the stubborn dermatitis mass in the abdomen in clinical, tinea manus and pedis have been carried out observation of curative effect respectively, its totall effective rate in clinical treatment is all more than 86%, relapse rate is low, proves that preparation of the present invention all has excellent therapeutic effect to plump keratinization dermatoses.
Claims (10)
1. treat dermopathic externally-applied medicinal composition for one kind, made by following components in weight percentage:
Radix Rumicis 30-120 part, Semen Hydnocarpi 30-120 part, Caulis Impatientis 10-70 part, Fructus Bruceae 10-70 part, Nidus Vespae 10-70 part, bright Flos Impatientis 10-70 part, Sal Ammoniacus 40-250 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 100-650 part, Resina garciniae (system) 50-350 part.
2. the pharmaceutical composition described in claim 1 is characterized in that, is made by following components in weight percentage:
Radix Rumicis 45-90 part, Semen Hydnocarpi 45-90 part, Caulis Impatientis 20-50 part, Fructus Bruceae 20-50 part, Nidus Vespae 20-50 part, bright Flos Impatientis 20-50 part, Sal Ammoniacus 70-180 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 220-500 part, Resina garciniae (system) 120-150 part.
3. the pharmaceutical composition described in claim 1-2 is characterized in that, is made by following components in weight percentage:
60 parts of Radix Rumiciss, 60 parts of Semen Hydnocarpis, 30 parts of Caulis Impatientiss, 30 parts of Fructus Bruceaes, 30 parts of Nidus Vespaes, 30 parts of bright Flos Impatientiss, 120 parts of Sal Ammoniacus, 350 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 1 part of Resina garciniae (system).
4. the pharmaceutical composition described in claim 1-3 is characterized in that, also comprises any one or more components of following weight proportioning in its prescription:
Scolopendra 5-40 part, Mylabris (system) 5-40 part, Squama Manis (system) 5-40 part, Scorpio 5-40 part.
5. the preferred weight proportioning of the medicine components that increases in the pharmaceutical composition described in claim 4 is: 15 parts of Scolopendras, 15 parts of Mylabris (system), 15 parts of Squama Maniss (system), 15 parts of Scorpios.
6. the pharmaceutical composition described in claim 1-5 is characterized in that, also comprises any one or more components of following weight proportioning in its prescription:
Flos Rhododendri Mollis 10-50 part, Radix Aconiti (system) 5-30 part, Radix Aconiti Kusnezoffii (system) 5-30 part, Semen Strychni (system) 10-50 part.
7. the preferred weight proportioning of the medicine components that increases in the pharmaceutical composition described in claim 6 is:
30 parts of Flos Rhododendri Mollis, 15 parts of Radix Aconitis (system), 15 parts of Radix Aconiti Kusnezoffii (system), 30 parts of Semen Strychni (system).
8. the pharmaceutical composition described in claim 1-7 is characterized in that, also comprises any one or more components of following weight proportioning in its prescription:
Spina Gleditsiae 10-70 part, Radix Stemonae 10-70 part, Semen Ginkgo 10-70 part, Semen Armeniacae Amarum 10-70 part.
9. the preferred weight proportioning of the medicine components that increases in the pharmaceutical composition described in claim 6 is:
30 parts of Spina Gleditsiaes, 30 parts of the Radixs Stemonae, 30 parts of Semen Ginkgoes, 30 parts of Semen Armeniacae Amarums.
10. the pharmaceutical composition described in claim 1-9 is characterized in that, also comprises any one or more components of following weight proportioning in its prescription:
Calomelas 50-350 part, Plumbum preparatium 1000-3500 part.
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| CN2013100809168A CN103251805A (en) | 2013-03-08 | 2013-03-08 | Externally-applied pharmaceutical composition for treating dermatopathy |
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| CN2013100809168A CN103251805A (en) | 2013-03-08 | 2013-03-08 | Externally-applied pharmaceutical composition for treating dermatopathy |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105169139A (en) * | 2015-11-05 | 2015-12-23 | 孙颖 | Pharmaceutical preparation for treatment of skin diseases |
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| CN1079144A (en) * | 1993-04-23 | 1993-12-08 | 徐殿基 | Synthetic cleanout fluid of a kind of natural plants (being Chinese herbal medicine) and preparation method thereof |
| CN1695659A (en) * | 2004-05-13 | 2005-11-16 | 余炜 | Method of preparing medicine for treating condyloma acuminatum |
| CN102451377A (en) * | 2010-10-19 | 2012-05-16 | 叶永兴 | Preparation method of psoriasis treatment tincture |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1079144A (en) * | 1993-04-23 | 1993-12-08 | 徐殿基 | Synthetic cleanout fluid of a kind of natural plants (being Chinese herbal medicine) and preparation method thereof |
| CN1695659A (en) * | 2004-05-13 | 2005-11-16 | 余炜 | Method of preparing medicine for treating condyloma acuminatum |
| CN102451377A (en) * | 2010-10-19 | 2012-05-16 | 叶永兴 | Preparation method of psoriasis treatment tincture |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105169139A (en) * | 2015-11-05 | 2015-12-23 | 孙颖 | Pharmaceutical preparation for treatment of skin diseases |
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Application publication date: 20130821 |