CN103784541A - Traditional Chinese medicine for treating pains on neck, shoulders, waist and legs - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating pains on neck, shoulders, waist and legs. The traditional Chinese medicine is prepared from the following traditional Chinese medicines: flowers carthami, peach kernels, native copper, frankincense, myrrh, roots of red-rooted salvia, radix achyranthis bidentatae and raw liquorice. The traditional Chinese medicine disclosed by the invention has the functions of regulating qi and activating blood, cooling blood and eliminating carbuncle, dissipating stasis and reliving pains, relaxing tendon and activation collaterals, warming channel and expelling cold, dispelling wind and eliminating dampness, softening hard lumps and dispelling nodes, strengthening tendons and bones, improving microcirculation, nourishing nerves, promoting fracture healing and the like. The traditional Chinese medicine disclosed by the invention is simple in production process, reasonable in formula, safe, free from toxic and side effect, quick in effect and remarkable in curative effect.

Description

A kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain

Technical field

The invention belongs to technical field of Chinese medicines, relate in particular to one and there is blood circulation promoting and blood stasis dispelling, dispelling cold by warming the meridian, the Chinese medicine of the treatment neck-shoulder pain, lumbago and leg pain of relaxing muscles and tendons and activating QI and blood in the collateral analgesic effect.

Background technology

Medically, pain is one of modal symptom, but the character of pain difficult description extremely sometimes, as tell twinge, causalgia, jumping pain, dull pain or angor etc.All people fear pain, all live through pain and are perplexed by it.Pain is classified as the fifth-largest vital sign after breathing, pulse, blood pressure, body temperature by modern medicine.Clinically, rheumatism, rheumatoid arthrosis disease, chronic strain disease and bone fracture and injury have become the commonly encountered diseases that causes pain, frequently-occurring disease.Particularly middle-aged and elderly people, the group of people at high risk that still do not fracture, and the chronic disease that has the aspects, joint such as various necks in various degree, shoulder, waist, lower limb over half.Theory of Chinese medical science thinks, pain is that human body is subject to invading to scratch and causing of " wind, cold, wet, heresy ".Yin and yang imbalance, coagulation of QI-blood, deficiency of both the liver and kidney, the heresy of diseases caused by exogenous pathogenic factor cold-damp all can cause pain.At present various for the medicament categories of pain relieving on the market, but analgesic effect is not remarkable mostly.Though also having part analgesic to have certain analgesic effect but control table does not effect a permanent cure.Except medication, also useful physical therapy method pain relieving, as acupuncture-moxibustion, fiery treatment, magnetic therapy, far infrared are treated, operative treatment etc. even, these methods have certain shortcoming.

Bone injury is to cause the commonly encountered diseases of pain, if fracture long-term protracted course of disease, more brings larger misery to patient.For patient with bone fracture, resetting, fixing in, should give orthopedic drug treatment, with fast track rehabilitation, reduce painful.Along with the development of China's traditional Chinese medical bone fracture, though obtaining rapid progress aspect treatment fracture, still lack very perfect medicine at present.Such as, effective fast, act on strong Western medicine, act on single, can not wholistic therapy, and toxic and side effects is large; The Chinese medicine of blood circulation promoting and blood stasis dispelling is not that effect is too poor, is exactly the feelings of not augmenting flesh and blood.Only can blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, can induce blood capillary, nerve net, osteocyte to generate fast again, can also provide sufficient, comprehensively nutrition supplying damage respectively organize rapid regeneration, reparation, and there is no toxic and side effects, such Chinese medicine is only desirable medicine.

Summary of the invention

Object of the present invention is exactly the problem existing for above-mentioned technology, provide one to there is blood circulation promoting and blood stasis dispelling, dispelling cold by warming the meridian, relaxing muscles and tendons and activating QI and blood in the collateral, the Chinese medicine of the effects such as bone growth promoting pain relieving, is not only adapted to the various treatment of organizing pain, also be applicable to the treatment of bone injury, this medicine processing technology is simple, easy to use, and cure rate is high.

This preparation be inventor by excavating classical Chinese medicine ancient books, inherit ancestors efficacious wonderful recipe, in conjunction with clinical experiences in a large number, carry out large quantity research and draw.The present invention is made up by weight ratio of following traditional Chinese medicines:

Flos Carthami 10-20g, Semen Persicae 10-20g, Pyritum 10-20g, Olibanum 10-20g, Myrrha 10-20g, Radix Salviae Miltiorrhizae 10-20g, Radix Achyranthis Bidentatae 5-15g, Radix Glycyrrhizae 3-9g.

Optimum weight proportion is:

Flos Carthami 15g, Semen Persicae 15g, Pyritum 15g, Olibanum 15g, Myrrha 15g, Radix Salviae Miltiorrhizae 15g, Radix Achyranthis Bidentatae 10g, Radix Glycyrrhizae 6g.

Above-mentioned each component is made to preparation method of the present invention to be completed in the steps below:

(A) take each weight portion: Flos Carthami 10-20g, Semen Persicae 10-20g, Pyritum 10-20g, Olibanum 10-20g, Myrrha 10-20g, Radix Salviae Miltiorrhizae 10-20g, Radix Achyranthis Bidentatae 5-15g, Radix Glycyrrhizae 3-9g;

(B) above each component mixing and water adding decocts 2 times, adds for the first time 5 times of water gagings to decoct 2h, adds for the second time 2 times of water gagings to decoct 1h, merges 2 times decoction liquor, filters filtrate simmer down to thick paste;

(C) appeal thick paste be dry, pulverize into fine powder, crosses after 120 mesh sieves and mix well, the close-beat-rubbing of sterilizing-join-with become 3g medicinal pill package to complete the present invention.

The present invention also can make powder, decoction, capsule etc. according to actual needs.

At this, above prescription is illustrated: wherein Flos Carthami: acrid in the mouth, warm in nature.GUIXIN, Liver Channel.Its gas perfume (or spice), can manage it and fall apart, and enters blood system and has promoting blood circulation to restore menstrual flow, effect of stasis-dispelling and pain-killing.Cure mainly blood stasis amenorrhea ， mass in the abdomen mass in the abdomen, difficult labour, retention of dead fetus, disease that postpartum lochia can't go, obstruction of qi in the chest and cardialgia, abdominal pain due to blood stasis rib hypochondriac pain, traumatic injury, the stasis of blood is stagnant to swell and ache, apoplectic hemiplegia, numbness relieving and pain relieving, the diseases such as sore throat; Semen Persicae: bitter in the mouth, sweet, property is flat.GUIXIN, liver, large intestine channel.There is blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, the effect of relieving cough and asthma.For amenorrhea, dysmenorrhea, wEIJIAmass in the abdomen, injury from falling down, dryness of the intestine constipation.Modern medicine chemical analysis: Semen Persicae contain amygdaloside, semen Armeniacae Amarum enzyme, volatile oil, oleinon a small quantity linoleic acidglyceride, its water decoction and extract have analgesia, antiinflammatory, antibacterial, anti-allergic effects; Pyritum: acrid in the mouth, property are flat, nontoxic.Return Liver Channel.There is dissipating blood stasis, synthetism, the effect of pain relieving, is conventional promoting blood circulation, removing blood stasis and relieving pain medicine.Cure mainly treating swelling and pain by traumatic injury, injured bone, has the effect that promotes union of fracture; Olibanum: bitter in the mouth is pungent, warm in nature.Enter the heart, liver, spleen channel.Have regulating qi and activating blood, analgesic therapy, chases after malicious effect.Cure mainly coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge; Myrrha: bitter in the mouth, property is pungent, warm, nontoxic.Enter liver, spleen, the heart, kidney channel.There is the effect of antibacterial, antimicrobial, antiinflammatory, convergence, there is special balosam matter.For deodorization, the flatulence of dispelling, sterilization, diuresis, stimulate the menstrual flow, reduce phlegm, antifungal, excitation, sharp stomach, urge antiperspirant, mend body, sharp uterus, control wound, to ripe, dry and cracked, coarse skin is all helpful; Radix Salviae Miltiorrhizae: bitter in the mouth, property is flat, tepor.Enter the heart, Liver Channel.There is promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, effect of nourishing blood to tranquillize the mind.Modern pharmacological research confirms: Radix Salviae Miltiorrhizae has heart tonifying, protects the liver, the effect of antibacterial, blood fat reducing, can expand peripheral blood vessel, reduces cardiac load, promotes graft function, improves microcirculation, antithrombotic forms, and promotes reparation and the regeneration of tissue, promotes union of fracture; Radix Achyranthis Bidentatae: bitter in the mouth, acid, property is flat.Return liver, kidney channel.Promoting blood circulation to remove obstruction in the collateral, removing blood stasis blood stasis dispelling, broken disease relieving accumulation of pathogens, arranges swollen pain relieving, strong waist knee joint, strengthening bone and muscle, invigorating the liver and kidney, wind-damp dispelling.For cold-damp flaccidity syndrome and arthralgia syndrome, spasm of the limbs, gonalgia unable to flex and stretch the extremities; Radix Glycyrrhizae: lung, spleen, stomach warp are put down, returned to sweet in the mouth, property.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, eliminates the phlegm and quenches the thirst, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, separates hundred poison.

All medicines share above, have dispelling cold by warming the meridian, expelling wind and removing dampness, and blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, hard masses softening and resolving, relieving spasm to stop pain, antiinflammatory degerming, diuresis is stimulated the menstrual flow, detumescence toxin expelling, strengthening vital QI to eliminate pathogenic factors, trophic nerve, activating cell, improves microcirculation, promotes the effects such as union of fracture.

Medicine of the present invention has the following advantages:

1. the present invention is pure Chinese medicinal preparation, and drug effect is rapid, and curative effect is lasting.

2. material source of the present invention is extensive, and formula is reasonable, moderate cost.

3. the present invention is without secondary toxic action, safety easy to use.

The specific embodiment

Embodiment 1

According to following weight parts, take each raw material:

Flos Carthami 10g, Semen Persicae 10g, Pyritum 10g, Olibanum 10g, Myrrha 10g, Radix Salviae Miltiorrhizae 10g, Radix Achyranthis Bidentatae 5g, Radix Glycyrrhizae 3g.

Make in the steps below the Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain:

(A) take each weight portion: Flos Carthami 10g, Semen Persicae 10g, Pyritum 10g, Olibanum 10g, Myrrha 10g, Radix Salviae Miltiorrhizae 10g, Radix Achyranthis Bidentatae 5g, Radix Glycyrrhizae 3g;

(B) above each component mixing and water adding decocts 2 times, adds for the first time 5 times of water gagings to decoct 2h, adds for the second time 2 times of water gagings to decoct 1h, merges 2 times decoction liquor, filters filtrate simmer down to thick paste;

(C) appeal thick paste be dry, pulverize into fine powder, crosses after 120 mesh sieves and mix well, the close-beat-rubbing of sterilizing-join-with become 3g medicinal pill package to complete the present invention.

[usage and dosage]

Each 1 time of this product morning and evening every day, each 1 ball, warm boiled water.Seriously ill patient can the morning, noon and afternoon each 1 time.

[subject range]

Rheumatic ostalgia, neck-shoulder pain, lumbago and leg pain, sciatica, arthralgia, swelling and pain due to blood stasis, limbs are cold and cool aches, fracture pain, union of fracture etc.(pain that fracture is caused has specially good effect).

[points for attention]

Hypertension, hyperglycemic patients are cautious use of.Severe cardiac disease of ZANG-organs, hypertension, diabetics forbidding.Anemia of pregnant woman, age of sucking, menstrual phase or have Xue Pour to forbid to person.10 years old following child's forbiddings.

[taboo], in the time that property of drug changes, forbids.

[storage] puts shady and cool lucifuge place and the impalpable place of child.

Lower 3 years of [effect duration] room temperature.

Embodiment 2

Take each raw material according to following weight parts:

Flos Carthami 20g, Semen Persicae 20g, Pyritum 20g, Olibanum 20g, Myrrha 20g, Radix Salviae Miltiorrhizae 20g, Radix Achyranthis Bidentatae 15g, Radix Glycyrrhizae 9g.

Make in the steps below the Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain:

(A) take each weight portion: Flos Carthami 20g, Semen Persicae 20g, Pyritum 20g, Olibanum 20g, Myrrha 20g, Radix Salviae Miltiorrhizae 20g, Radix Achyranthis Bidentatae 15g, Radix Glycyrrhizae 9g;

(B) above each component mixing and water adding decocts 2 times, adds for the first time 5 times of water gagings to decoct 2h, adds for the second time 2 times of water gagings to decoct 1h, merges 2 times decoction liquor, filters filtrate simmer down to thick paste;

(C) appeal thick paste be dry, pulverize into fine powder, crosses after 120 mesh sieves and mix well, the close-beat-rubbing of sterilizing-join-with become 3g pill package to complete the present invention.

[usage and dosage] [subject range] [points for attention] [taboo] [storage] [effect duration] is with embodiment 1.Embodiment 3

Take each raw material according to following weight parts:

Flos Carthami 15g, Semen Persicae 15g, Pyritum 15g, Olibanum 15g, Myrrha 15g, Radix Salviae Miltiorrhizae 15g, Radix Achyranthis Bidentatae 10g, Radix Glycyrrhizae 6g.

Make in the steps below the Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain:

(A) take each weight portion: Flos Carthami 15g, Semen Persicae 15g, Pyritum 15g, Olibanum 15g, Myrrha 15g, Radix Salviae Miltiorrhizae 15g, Radix Achyranthis Bidentatae 10g, Radix Glycyrrhizae 6g, above drug component is made medicinal liquid according to existing routine techniques;

(B) above each component mixing and water adding decocts 2 times, adds for the first time 5 times of water gagings to decoct 2h, adds for the second time 2 times of water gagings to decoct 1h, merges 2 times decoction liquor, filters filtrate simmer down to thick paste;

(C) appeal thick paste be dry, pulverize into fine powder, crosses after 120 mesh sieves and mix well, the close-beat-rubbing of sterilizing-join-with become 3g medicinal pill package to complete the present invention.

[usage and dosage] [subject range] [points for attention] [taboo] [storage] [effect duration] is with embodiment 1.Pharmacodynamic study

In order to verify drug effect of the present invention, inventor has carried out pharmacodynamic study with rat

Animal and raising condition:

Rat group support, freely absorbs solid feed and tap water, room temperature 20 ± 5C.

Medicine preparation:

Pill is pulverized, and distilled water decocts 2 hours, gets supernatant and makes 80% solution for standby.

Experimental technique and result:

One, antiinflammatory action (arthroncus method):

40 of healthy SD kind rats, body weight 200 ± 20g, male and female are regardless of.Be divided at random 4 groups, 10 every group.A group: normal saline matched group (2ml/100g); B group: small dose group (1ml/100g, every 1ml is containing 0.8g crude drug, lower same); C group: heavy dose of group (3ml/100g) and D group: positive controls (0.25% dexamethasone sodium phosphate 0.2ml/100g).A, B, tri-groups of gastric infusions of C, D organizes intraperitoneal injection.Measure simultaneously and record the girth of the right hind ankle of each Mus.After each Mus administration 20min, from right back vola mind-set ankle joint direction subcutaneous injection 1% carrageenin solution 0.2ml.And 1h after difference surveying record injection proinflammatory agent, 2h, the right ankle girth of 3h and 24h, after injection proinflammatory agent, girth deducts original girth, is the right back paw swelling of each time.Experimental result is in table 1.

Table 1 the present invention causes the impact (x ± SD) of ankle swelling in rat melon on pitching dish sol solution January

P<0.03

Experimental result shows, the heavy dose of group of Chinese medicine that the present invention is a kind of treats neck-shoulder pain, lumbago and leg pain bone can significantly alleviate chondrus ocellatus Holmes and cause the swelling of rat ankle joint.

Show that the present invention has good anti-inflammatory effect.

Two, analgesic activity

(1) hot plate method: get 24 of ICR mices, female, body weight 20 ± 3g.Be divided at random three groups: normal saline group, medicine group is that 80% medicinal liquid is with 10g/kg gavage, positive controls is that subcutaneous injection 0.25% pethidine 0.1ml/10g. experiment interlayer iron sheet water bath, constant temperature makes bath temperature remain on 56 ℃, mice is placed on hot plate, drops into the index of hot plate when the time that occurs licking metapedes, (incubation period) was as the threshold of pain from mice with stopwatch record.If the mice administration front threshold of pain time is less than 5 seconds or is greater than 60 seconds, thinking too responsive or insensitive and remove need not.The results are shown in Table 2.

(2) writhing method: get 30 of ICR mices, male and female half and half, body weight 20 ± 2g.Be divided at random three groups, wait capacity normal saline group; Medicine group is that 80% medicinal liquid is with 15g/kg gavage; Positive controls is 0.25% pethidine 0.1ml/mg subcutaneous injection.After administration 30 minutes, every Mus is by Intraperitoneal injection 0.05% antimony potassium tartrate 0.5ml.Then observe each Mus in 10 minutes whether writhing response and writhing number of times occur.The results are shown in Table 3.

Experimental result demonstration, compares with normal saline matched group, and the present invention can obviously reduce Mus writhing number of times, and analgesic activity has been described.

Table 2 the present invention causes the unit that affects of mice pain reaction on hot plate: second

Before * P<0.01 and administration, compare

Result of the test shows, the present invention significantly improves mice pain threshold value, and analgesic activity has been described.

Table 3 the present invention causes the impact of pain mice pain reaction on chemistry

With relatively * * P<0.02 of normal saline group

Conclusion

1, a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain of the present invention has antiinflammatory action, can resist chondrus ocellatus Holmes and cause the effect of ankle swelling in rat.

2, a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain of the present invention has good analgesic activity, soaks foot to mice, can reduce hot plate method induced pain threshold.

Toxicologic study

Toxicological test

(1) experimental data

Tested material: a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain.Pill is pulverized, and distilled water decocts 2 hours, and getting supernatant, to make 50% liquid for subsequent use.

Animal and raising condition: healthy S1) plant rat, body weight 220 ± 15g, male and female half and half, point cage group support, conventional solid feed and tap water freely absorb, receptacle temperature 18～C-25～C.

Experimental technique and result:

160 of SD kind rats, male and female half and half, be divided at random four groups: water matched group (1ml/100g), a kind of Chinese medicine small dose group (2ml/kg is equivalent to people's consumption) for the treatment of neck-shoulder pain, lumbago and leg pain, middle dosage group (4ml/kg is equivalent to 2 times of people's consumption), heavy dose of group (8ml/kg is equivalent to 4 times of people's consumption), every day gavage once, continuous 6 months, monthly weigh once, and observe its appetite, outward appearance, behavior, secretions, feces etc., 6 months each groups of gavage are put to death 20 animals, broken end is got blood, carry out hematology, blood biochemical is learned check, main organs is carried out to pathological examination.Result is as follows:

(2), the observation of general status

After pouring into medicinal liquid, observe day by day, in, small dose group animal appearance is normal, hair is glossy, activity freely, ingest, feces etc. is showed no extremely, and body weight increases gradually, without rubbing hands, perpendicular tail, comfort face, lisp, the excited situation such as whole body vibration, with matched group comparison, all no significant differences (P>0.05).Heavy dose of treated animal pour into medicinal liquid after 6 months without perpendicular hair, movable normal (in experiment, paying special attention to observe animal behavior), body weight gain is good, with matched group comparison, not significantly (P>0.05) of difference.In table 4.

Table 4 Chinese medicine long-term (6 months) for the treatment of neck-shoulder pain, lumbago and leg pain pours into the impact on rat body weight

unit: g

With relatively * P>0.05 of matched group

(3), hematological examination

In testing the 3rd the end of month by rat sacrificed by decapitation half, hematological examination is done in blood sampling immediately, and result shows, each dosage treated animal hematology indices, all within normal range, with matched group comparison, no significant difference (P>0.05), as table 5 shows:

The impact of index is learned in long-term (3 months) medication of Chinese medicine that one kind, table 5 is treated neck-shoulder pain, lumbago and leg pain on rat blood

(4), blood biochemistry checking

In testing the 3rd the end of month, the rat that distinguish sacrificed by decapitation respective numbers the 6th the end of month, carries out rat blood serum SGPT, SGOT, total protein, albumin, total bilirubin, blood urea nitrogen, creatinine inspection routinely:

Press reitman-frankel method and survey SGPT, unit (U/L)

Press reitman-frankel method and survey SGOT, unit (U)

Press biuret method and survey total serum protein, unit (g/L)

Result is shown as table 6:

With relatively * P>0.05 of matched group

Above result shows, at a kind of 6 the end of month of Chinese medicine gavage for the treatment of neck-shoulder pain, lumbago and leg pain, rat blood serum SGPT and SGOT are without obvious rising, and with matched group comparison, difference is remarkable (P>0.05) not.Prove other project of liver function and renal function to have no significant effect.

(5), pathological examination

In testing 3 the end of month and 6 the end of month and recovering end of term sacrificed by decapitation rat, dissect rapidly each internal organs in perusal body, and take out the heart, liver, spleen, lung, kidney, ovary, fallopian tube, uterus, testis, epididymis, thymus, adrenal gland, rib and mesenteric lymph node, and fix with 10% formaldehyde, make pathological examination.Result shows, uses a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain after 3 months to rat oral gavage, and each histiocyte form of each dosage treated animal is normal, with matched group no significant difference; After 6 months, each histiocyte of each dosage treated animal has no special pathological change.

Above result shows, a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain of long-term taking has no significant effect the dirty body ratio of rat major organs.

Brief summary

Two kinds of sexes of 3 months and 6 months have been carried out in this test to rat oral gavage with a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain, the long term toxicity test of Three doses, high dose group is equivalent to 8 times of people's consumptions, with matched group comparison, in, the general status of small dose group animal is good, hematology's indices, liver function, kidney merit are all normal, each dirty body is than comparing no significant difference, each organ-tissue pathologic finding no abnormality seen with matched group.High dose group (4ml/kg) rat is without poisoning symptom, and body weight gain is normal, and pathologic finding finds that the heart, liver, nephrocyte are without significant change.

Clinical observation on the therapeutic effect

Clinical observation on the therapeutic effect 1

1, clinical data

Select outpatient service and bone injury case totally 220 examples of being in hospital, wherein test group 160 examples, account for 72.7%, and matched group 60 examples, account for 27.3%.All cases all meets case selection standard.220 routine cases adopt completely random grouping, and patient strictly controls variable factor and white row drug combination, to protect the comparability of just testing, and two groups of other medicines of all stopping using of viewing duration.

2, observational technique:

2.1, test group: oral the present invention: a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain, 3g ball, 1,2 times/day, 1 ball, sooner or later respectively once, 1 month is a course for the treatment of;

2.2, matched group: Orally taken fracture setting ball, a 3g, twice, 1 month on the one is a course for the treatment of.

2.3, test combinations matched group was all observed medication effect after one month.

3, observed result

3.1, test group cardinal symptom is treated improvement situation in front and back after 1 month, refers to table 7.

Improvement situation before and after the treatment of table 7 test group cardinal symptom

Symptom	(+) N before treatment	(+) N after treatment	Improve number N	Improvement rate (%)
					Pain	210	10	200	95.23
Numb	180	28	152	84.45
					Unable	160	16	144	90.00

As can be seen from the above table, test group pain, numbness, the rear improvement rate of unable treatment are respectively: 90.91%, 84.45%, 90.00%.

3.2, general curative effect, in table 8.

Table 8 liang group general curative effect contrast table

Group	Effective percentage	Inefficiency	Total effective rate
				Test group	92.8	7.2	96.7
Matched group	76.7	23.3	80.5

The total effective rate of two groups of general curative effects be respectively 96.7% and 89.5%, two group have significant difference, p<0.02.Show that test group general curative effect is obviously better than matched group.

4, conclusion

4.1, the effect of a kind of various pain for the treatment of by Chinese herbs for the treatment of neck-shoulder pain, lumbago and leg pain of the present invention is remarkable, and it improves Clinical Pain symptom effective percentage is 90.8%, and total effective rate is 96.7%;

4.2, the present invention is almost recovered 220 routine patients, and its cure rate reaches 94.25%;

4.3, in application process, do not find toxic and side effects and untoward reaction.

Clinical observation on the therapeutic effect 2

Observe a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain of the oral the present invention of 380 routine treatment group, the oral pill for treating rheumatism and alleviating pain of 250 routine matched group is existing is summarized as follows observed result:

1. physical data

380 examples, are non-inpatient herein, comprise scapulohumeral periarthritis, lumbar muscle strain, rheumatic arthritis, rheumatoid arthritis.Its sex, age, occupation are in table 9.

2. Therapeutic Method and curative effect determinate standard

(1) Therapeutic Method:

Treatment group: oral the present invention, 1 ball, a twice-daily, one month is a course for the treatment of.

Matched group: oral pill for treating rheumatism and alleviating pain, a 2.5g, a twice-daily, one month is a course for the treatment of.

(2) curative effect determinate standard:

(1) cure: symptomatology, sign disappear, and laboratory examination is normal;

(2) effective: main physical signs, transference cure or obviously improvement, laboratory examination index is improved;

(3) invalid: sign, symptom and laboratory indexes are without improvement.

3. want observation item and observed result

1. main observation item: rheumatoid arthritis; Rheumatic arthritis; Rheumatism, cold-damp scapulohumeral periarthritis; Rheumatism, cold-damp lumbar muscle strain.

2. observed result: pass through 380 examples herein (comprising 120 Cases of Rheumatoid Arthritis, rheumatic arthritis 88 examples, scapulohumeral periarthritis 78 examples, lumbar muscle strain 94 examples) oral the present invention, clinical observation, result shows, the present invention all has certain curative effect to rheumatoid arthritis, rheumatic arthritis, scapulohumeral periarthritis, lumbar muscle strain, and its total effective rate is respectively 82%, 88.6%, 87.1%, 95.7%.The routine oral cold-damp sheet of matched group 260, through clinical observation, result shows, and cold-damp sheet all has certain curative effect to rheumatoid arthritis, rheumatic arthritis, scapulohumeral periarthritis, lumbar muscle strain, and its total effective rate is respectively 62%, 72.5%, 65.4%, 85%.Observation of curative effect of the present invention the results are shown in Table 10.

Table 10 observation of curative effect table of the present invention

4. conclusion

Rheumatoid arthritis, rheumatic arthritis, scapulohumeral periarthritis, lumbar muscle strain cause mainly due to wind, cold, wet.Mostly show as position pain or the swelling such as joint, muscle, muscles and bones.Morning deadlock, numbness, weighing or joint stuffiness, very joint swelling deformation, does not tetanicly stretch, amyotrophy.Theory of Chinese medical science is thought, is mainly that battalion defends deficiency, negative and positive of qi and blood imbalance, or deficiency of both the liver and kidney, and weakened body resistance and evil poison gathers in women's head-ornaments, feels again exopathogen, or double congestion, and the traditional Chinese medical science, take blood circulation promoting and blood stasis dispelling, invigorating kidney qi, regulating QI to relieve pain as starting point, is conducive to the reparation of damaged tissue.

The present invention has the functions such as expelling wind and cold, dampness removing blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian, invigorating kidney qi, regulating QI to relieve pain.380 routine clinical observation result, the present invention is to rheumatoid arthritis; Rheumatic arthritis; Scapulohumeral periarthritis, lumbar muscle strain etc. that wind, cold, wet causes have obvious curative effects, and total effective rate is 93.8% and is to find any untoward reaction at viewing duration, is worthy of popularization.

Clinical case

Case one: Xu certain, man, 51 years old, people from Ulan Hot, secondary school teachers.2 years fore rider vehicles of readme are fallen down, and right crus of diaphragm wrist is seriously sprained, though treated at that time, but ankle limitation of activity so far, pain, interior ankle is to foot thumb, food, the blue or green edema of the two finger place stasis of bloods, and numbness is unbearably, once took traditional Chinese medicine, steeped medical herbs, the wine curative effect of applying medicinal lotion or ointment is very micro-, 2011 with the present invention, and after two days, ankle can loose, and toe is numb to disappear, cold and cool alleviation, pain relief.After using one week, edema is subsided, and freely, numbness is removed completely in ankle activity, cold and cool basic disappearance.After two weeks, recover normal.

Case two: Lee, man, 62 years old, people from Ulan Hot, retired cadre, lumbar intervertebral disc 4,5 is outstanding, spinal canal stenosis pressuring nerve, waist hurt like hell,, is twitched to ankle place, outside by left Hip bone place, aching and limp, cold and cool numbness, heel pain can not trample ground.Hospitalization lumbago on the 60th is alleviated, other symptom still end is improved, and physician-in-charge advises operative treatment, because patient disagrees with operation, in May, 2011 seeks medical advice in here, use the present invention, after one week, cold and cool feeling of numbness disappears, pain relief, after 2 weeks, twitch and stop, within 4 weeks, the rear foot can be stepped on ground and can walk, all uncomfortable releasings after 8 weeks, and walking is freely.

Case three: Zhao, female, 36 years old, Baicheng City people, individuality, readme puerperal exposure to wind is cold, cause left arm cold and cool, sour, numb, swollen, bitterly, existing 7 or eight years, swathed summer with towel, can not wear cotta clothes, otherwise unbearably cold and cool, look round for medical treatment for many years, but the state of an illness is more and more serious, shoulder can not on lift, bending and stretching of the arms is unfavorable, agonizing.Over 8 moons in the last ten-days period in 2011, seek medical advice in here, uses the present invention one week pain to alleviate, and after 30 days, disease disappears, and has taken down the towel and the cotton dress that have swathed more than ten years, equally with normal person worn cotta.

Case four: Zhang, man, 64 years old, people from Tuquan County.Government functionary, suffers from cervical spondylosis and has a surplus for 10 years, and CT shows, neck 3,4,5 gap turn narrow, and neck 6 hypertrophy curvatures straighten.The pain that has a stiff neck, tinnitus, dizziness, turns neck symptom and increases the weight of, there is lump in both shoulders district, and all there is bar rope the neck left and right sides, rightly takes on to finger tip place all numb unbearably cold and coolly, and upper arm is praised limited, the difficulty of washing one's face, was once in hospital many days, and physical therapy first quarter moon, was showed no positive effect.In JIUYUE, 2012 is come here and is sought medical advice, and uses after the present invention upper arm in the future to praise, continue to use 45 after all transference cures, patient is very grateful, and send silk banner to express thanks.

Case five: Xue, man, 46 years old, people from Qiqihar.Certain field, pasture master, readme hour is grown up amid the mountains, poor because of family, make a living by herding, wind-guiding damp disease after having a cold, both shoulders, both arms, two knee joint, the equal pain numbness in biped joint, be again lumbar muscle strain, suffers untold misery.Foot pain swelled and increased the weight of to walk in July, 2010, came here and sought medical advice, and gave the present invention after 20 minutes 10 days. and on foot, pain is removed, and swelling is numb to be alleviated, and can walk.Use all transference cures after 60 days, after March, follow up a case by regular visits to without recurrence.

Case six: Ma 54 years old, Zha Laite bannerman, suffers from rheumatoid arthritis 30 years, and finger-joint, carpal joint, double knee joint and the equal congestion and swelling pain of right crus of diaphragm anklebone are cold and cool, numbness.Another puerperal cold headache outbreak often, monthly at least falls ill 2 times, hurt like hell all at every turn, and winter is more very.Constantly take medicine for many years, acupuncture treatment, unsatisfactory curative effect.Use first week cold and cool numb disappearance of the present invention on October 21st, 2012, all transference cures after 30 days, postpartum headache is again without recurrence so far.

More than wherein several cases that I treat nearly 500 routine patients with the present invention in recent years.In a word, the present invention is easy to use, evident in efficacy.

Claims (2)

1. treat a Chinese medicine for neck-shoulder pain, lumbago and leg pain, it is characterized in that this Chinese medicine is made up of the crude drug of following weight portion: Flos Carthami 10-20g, Semen Persicae 10-20g, Pyritum 10-20g, Olibanum 10-20g, Myrrha 10-20g, Radix Salviae Miltiorrhizae 10-20g, Radix Achyranthis Bidentatae 5-15g, Radix Glycyrrhizae 3-9g.

2. a kind of Chinese medicine for the treatment of neck-shoulder pain, lumbago and leg pain according to claim 1, is characterized in that the preferable amount of each crude drug is: Flos Carthami 15g, Semen Persicae 15g, Pyritum 15g, Olibanum 15g, Myrrha 15g, Radix Salviae Miltiorrhizae 15g, Radix Achyranthis Bidentatae 10g, Radix Glycyrrhizae 6g.