CN103211118B - Additive for promoting postpartum recovery of sow as well as preparation method and application thereof - Google Patents

Additive for promoting postpartum recovery of sow as well as preparation method and application thereof Download PDF

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CN103211118B
CN103211118B CN201310135461.5A CN201310135461A CN103211118B CN 103211118 B CN103211118 B CN 103211118B CN 201310135461 A CN201310135461 A CN 201310135461A CN 103211118 B CN103211118 B CN 103211118B
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王文杰
郑成江
宋青龙
朱树群
王黎文
何茹
宗学东
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Tianjin Academy of Agricultural Sciences
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Tianjin Institute of Animal Husbandry and Veterinary Science
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Abstract

The invention discloses an additive for promoting postpartum recovery of a sow as well as a preparation method and application of the additive. The additive comprises the following traditional Chinese medicinal materials by weight: 20-60g of seed of cowherb, 9-20g of motherwort, 10-40g of dandelion, 10-30g of astragalus, 10-40g of Chinese angelica, 10-30g of hawthorn, 6-12g of houttuynia cordata, 5-15g of szechuan lovage rhizome, 8-15g of uniflower swisscentaury root and 1-2mg of VB1. The invention further discloses application of the additive in preparing a medicine for promoting the postpartum recovery of the sow. According to the additive, the experimental result proves that the additive has the obvious effects of activating and enriching the blood, diminishing inflammation and removing leakage on the postpartum sow.

Description

A kind of additive that promotes sow Recovery and preparation method thereof and application
Technical field
The invention belongs to pannage additive technology field, relate to a kind of swinery production efficiency that improves, the method that reduces production costs, more specifically say a kind of applicable sow of having added specific traditional Chinese medicine ingredients in perinatal period to swinery feed addictive of the different phase of during oestrus and preparation method thereof and application again after wean.
Background technology
In Swine Production process, how to enhance productivity, reduce production costs, be the target that pig industry is pursued always.The enterprise of more and more raising pigs has recognized that the importance of cost management, how cost is effectively managed, and is our common realistic problem of paying close attention to.At present the cost of pig industry is mainly made up of by several respects such as the production efficiencys of, place colony house and personal management expense and swinery feed cost.Except reducing feed and production management cost, improve swinery production efficiency and become one of important channel reducing production costs.Therefore, people are placed on the research emphasis reducing production costs to improve in swinery production efficiency.China live pig produces compared with animal husbandry developed country, also has larger gap.As developed country sow is produced 2.4 nests per year, China sow is produced only 2.0 nests per year; Every, developed country delivers pork pig sow year for sale more than 22, and only 16, China.Swinery production efficiency is mainly determined by boar production efficiency and pig-breeding level.The height of sow production efficiency is the basis that determines economic benefit.If providing pork pig number to bring up to 22 by current 16 in sow year, the cost of breeding part will reduce 37.5%.
The factor that affects sow production efficiency mainly contains the survival rate of annual output nest number, nest litter size and the piglet of sow.This is further analyzed, can be divided into the number of live birth and annual every Farrowing nest number.Not being both of annual every Farrowing nest number causes annual every sow between different pig farms to give birth to the different most important factors of number pigs born.Adjusting and optimize the parity structure of feeding mother pig, the breeding cycle of shortening multiparity sow, is to improve sow production efficiency, realizes the key measure of the high farrowing of sow, high benefit.Impact year childbirth nest number because have gestational period length, lactation number of days and nonproductive number of days.Nonproductive number of days refers to each breeding cycle or annual central sow or sow pig neither the gestation number of days of non-lactation again.Be considered to affect the index of reproducting herd production efficiency most critical.This is not that nest litter size and Preweaning death rate are just inessential, but it is more much more difficult than nonproductive number of days to change nest litter size.
The gestational period, length was relatively fixing, therefore shortened nonpregnant phase number of days and just became the key point of enhancing productivity.Conventionally, adopt the method Shortening lactation period of early weaning, ultra-early weaning, thereby shorten nonpregnant number of days, sow just can oestrus tens days postpartum again, but according to domestic current cultivation level, employing ultra-early weaning piglet nurture difficulty strengthens, management condition requires strictly, sow recovery is more difficult.So also mainly adopt the mode of wean in 21-35 days postpartum in actual production.Generally speaking, be generally 28d lactation period, from wean to the number of days of breeding again, can be within 10d, and be on average 114d period of pregnancy, its scope is at 112~116d.If period of pregnancy, lactation period, nonproductive number of days are respectively 114d, 28d and 10d so.Therefore a broad sow can produce 2.4 tires every year in theory.In fact, the annual output tire number of the most of pig farms of China sow is at 1.9~2.0 tires.Reason is that the nonproductive number of days of sow is long.At present we with annual product 2.2 tires as improve target.The nonproductive number of days that like this, how to shorten sow just becomes the research emphasis that improves sow reproductive efficiency.
Summary of the invention
An object of the present invention is to disclose a kind of additive that promotes sow Recovery.
Another object of the present invention is its preparation method that discloses additive
A further object of the present invention is the application that discloses the application aspect of Chinese medicine additive in preparation promotion sow Recovery medicine.Wherein said sow Recovery refers to the lactagogue lactogenesis of first week point puerperium sow, blood circulation promoting and enriching, and anti-inflammatory, except evil leakage, is repaired injury of birth canal.
For achieving the above object, the invention discloses following technology contents;
Promote an additive for sow Recovery, it is characterized in that it is made up of the Chinese medicine of following weight:
Seed of cowherb 20-60 gram, motherwort 9-20 gram, dandelion 10-40 gram, Radix Astragali 10-30 gram, Radix Angelicae Sinensis 10-40 gram, hawthorn 10-30 gram, cordate houttuynia 6-12 gram, Ligusticum wallichii 5-15 gram, Radix Rhapontici seu Radix Echinopsis 8-15 gram, VB1 1-2 milligram.
Additive of the present invention, preferably the weight of Chinese medicine is: 50 grams of the seeds of cowherb, 10 grams of motherworts, 20 grams of dandelions, 20 grams of the Radixs Astragali, 30 grams of Radix Angelicae Sinensis, 10 grams of hawthorn, 10 grams of cordate houttuynias, 10 grams of Ligusticum wallichiis, 10 grams of Radix Rhapontici seu Radix Echinopsis, 1.5 milligrams of VB1.
The present invention further discloses the preparation method of additive, it is characterized in that being undertaken by following step:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then mixed according to formula;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 60min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) taking corn flour as carrier, corn flour is dried two hours in 105 DEG C of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the VB1 of formula Design evenly to mix, 65 DEG C of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight.
(6) complete according to above-mentioned steps successively processing and fabricating, then carry out packing with valve bag according to the concrete addition of formula, 4 DEG C of dry environments are preserved.
The present invention's Chinese medicine effect used is as follows with effect:
Taking the seed of cowherb, motherwort, dandelion as main, activating blood to promote menstruation, lactogenesis detumescence, promotes galactosis.The Radix Astragali, auxiliary when being classified as, enriches blood and invigorates blood circulation, strengthens the body resistance to consolidate the constitution, and tonifying middle-Jiao and Qi, invigorating the spleen is promoted the production of body fluid, and promotes tissue repair and regeneration.Cordate houttuynia, Radix Rhapontici seu Radix Echinopsis are for assistant, clearing heat and detoxicating, the swollen-removing carbuncle that disappears, and treatment inflammation in postpartum, removes evil leakage, and Ligusticum wallichii is joined hawthorn for making, and the promoting flow of qi and blood circulation, purging intense heat row water are promoting blood circulation.VB1 coordinates Chinese medicine to accelerate sow anti-inflammatory in postpartum except lochia.
As the additive product that promotes sow Recovery, the composition of Chinese herb feed additive and dosage are two essence marrow of additive.In many cases, even the prescription of same medicine composition, because the consumption difference of each ingredients, its medication effect is also different.The selected formula of the present invention is mainly the lactagogue lactogenesis that is applied to first week point puerperium sow, promotes sow Recovery.Therefore, the effect of compound additive of the present invention is to embody by the acting in conjunction of all the components in prescription, and the proportioning of therefore selecting specific raw material and definite stock yard is the key of additive.
Principle below having followed aspect the determining of raw material, the proportioning of stock yard:
(1) this test basis Chinese veterinarian theory and Chinese herbal medicine combination principle carry out prescription, each taste Chinese herbal medicine is carried out to oxicity analysis and screening, each taste Chinese herbal medicine of selecting is actual nontoxic level Chinese herbal medicine, adhere rigidly to drug matching principle in compatibility process, avoid the incompatibility of Chinese medicine " eighteen incompatibilities, nineteen counteraction ", and use for reference the compatibility theory of traditional ripe proved recipe.The use amount that in prescription, each medicine addition is all recommended experience prescription in addition and traditional prescription with reference to " China's book on Chinese herbal medicine ".
(2) in palatability testing process, sow is carried out to the quintuple of the maximum addition of formal test and add, feed and within seven days, do not find any bad reaction or toxic reaction.
(3) finally determine: 50 grams of the seeds of cowherb, 10 grams of motherworts, 20 grams of dandelions, 20 grams of the Radixs Astragali, 30 grams of Radix Angelicae Sinensis, 10 grams of hawthorn, 10 grams of cordate houttuynias, 10 grams of Ligusticum wallichiis, 10 grams of Radix Rhapontici seu Radix Echinopsis, 1.5 milligrams of VB1.
The present invention is in order to promote sow body condition in postpartum to recover, shorten inter oestrual period, to improve sow reproductive efficiency, the present invention selects that Breeding date is close, reproductive performance, body condition (originate in a pig kind of Denmark without the white sow of the purebred length of multiparity of significant difference, English name: Landrace, be called " Landrace " old China hand), be divided at random test group and control group.According to emphasis and traditional Chinese medicine theory and the proved recipe of regulation and control, Chinese prescription is determined in screening.
The more detailed preparation method of the present invention is as follows:
(1) material of experiment: the seed of cowherb, motherwort, dandelion, the Radix Astragali, Radix Angelicae Sinensis, hawthorn, cordate houttuynia, Ligusticum wallichii, Radix Rhapontici seu Radix Echinopsis are purchased from Tianjin Zhong Xin medicine company group, and quality is carried out by NF requirement standard.VB1 is purchased from BASF AG.
(2) method of experiment:
1) use the electronic scale that minimum scale is 0.2g, each taste Chinese herbal medicine is weighed according to the addition of formula Design, then mix according to formula.
2) ratio of water: Chinese medicine=5:1 is soaked compatibility Chinese herbal medicine 60min, and in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters.The dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters.
3) merging filtrate, heating is concentrated into medicine, liquor ratio is 1:1, and 1ml liquid is equivalent to crude drug 1g, notes stirring, and can not occur enduring paste phenomenon.
4) taking corn flour as carrier, corn flour is dried two hours in 105 DEG C of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the VB1 of formula Design evenly to mix, 65 DEG C of drying in oven, obtain the finished product herbal prescription identical with crude drug in whole weight.
Complete according to above-mentioned steps successively processing and fabricating, then carry out packing with valve bag according to the concrete addition of formula, 4 DEG C of dry environments are preserved.Wherein in formula, Radix Angelicae Sinensis, Ligusticum wallichii, Radix Rhapontici seu Radix Echinopsis, cordate houttuynia are the Chinese medicine containing a large amount of volatile oil materials, should be afterwards under, so add again after water boils 20min; The seed of cowherb is because large usage quantity is easily sticking, and application gauze bag is decocted a drug wrapped.
Basal diet and trophic level
According to the trophic level in the large scale of pig farm actual production of Tianjin in contrast; the level of simultaneously advising using U.S. NRC pig nutritional requirements (1998), Chinese milking sow feeding standard (1987) nutritional need is as benchmark; determine basal diet formula and nutrient composition content between test sows in lactation, in table 1.
Table 1 milking sow basal diet composition and nutrient composition content
Raw material Proportioning (%) Nutritive index Nutrient content
Corn 60.00 Digestible energy (MJ/kg) 13.40
Dregs of beans 16.00 Crude protein (%) 16.64
Wheat bran 13.00 Lysine (%) 0.90
Fish meal 2.00 Ca(%) 1.35
Powered milk substitute 5.00 P(%) 0.52
Premix 4.00 ? ?
Remarks: 1. in nutritional labeling, crude protein, calcium, phosphorus are measured value, and all the other are calculated value, and the basal diet of two groups is identical.
2. the existing formula in direct application test place, measures conventional nutrient composition content in feed.
3. premix is produced by the honest feed corporation,Ltd in Tianjin.
20 sows are divided into 2 processed group at random, and each processed group is established 10 repetitions, 1 of each repetition.
Processing 1 is control group, the conventional daily ration of feeding; Processing 2 is test group, within 1--7 days, uses the Chinese herbal formula of design above in childbirth.7 days experimental periods.Test pig is taked the limit method of raising, and every morning 4 of 5:30 point and afternoons respectively feed once, and trial drug Feeding time is 5:30 point in morning, carry out with feeding for the first time simultaneously, by trial drug mix in feed hello to.
(3) experimental result:
The impact of Chinese herbal formula on the 7th day sow blood luteotropin level of giving a birth, in table 2
Table 2 the 7th day sow blood luteotropin concentration level (X ± S) (unit: mIU/ml) of giving a birth
As can be seen from Table 2, in childbirth the 7th day, test group and control group are compared: test group luteotropin level is a little more than control group, but not remarkable (P>0.05) of difference.
The impact of Chinese herbal formula on the 7th day sow blood follicle-stimulating hormone level of giving a birth, in table 3
Table 3 the 7th day sow blood follicle-stimulating hormone concentration level (X ± S) of giving a birth
(unit: mIU/ml)
As can be seen from Table 2, in childbirth the 7th day, test group and control group are compared: both follicle-stimulating hormone levels are close, and difference is not remarkable.
Sow birth canal in the postpartum lochia duration in table 4 sow stages of labor in table 3.
Table 4 sow stages of labor and lochia duration table (X ± S)
As can be seen from Table 3, test group is compared with control group: stages of labor no significant difference, but the test group stages of labor uniformity is higher, and the duration of giving a birth approaches; Test group birth canal in postpartum lochia Duration Ratio control group has shortened 0.7 day, shortens 17.24%, significant difference (P<0.05) than control group.
(5) conclusion: two groups of sow stages of labor no significant differences, but the uniformity of test group stages of labor is higher.Test group sow lochia Duration Ratio control group has shortened 17.24%.Significant difference.Stages of labor refers to that Farrowing starts the time finishing to childbirth, the factor that affects sow stages of labor length mainly contains kind, parity, age nutrition, management and individual health situation, in test, locate outside individual health situation, other factors are all identical, so stages of labor is more concentrated, may be because sow Reproductive Health difference is less.Prolonged lochia is one of sow apocleisis in postpartum or the syndromic main inducing of agalasisa in postpartum.Theory of traditional Chinese medical science thinks, mostly its pathogenesis of prolonged lochia be due to Qi and blood deficiency, stagnant in hemostasis, new blood must not return through.Motherwort, Radix Angelicae Sinensis blood-activating and qi-promoting in prescription, dandelion, clearing and activating the channels and collaterals, cordate houttuynia, Ligusticum wallichii, Radix Rhapontici seu Radix Echinopsis removing toxicity for detumescence, coordinate VB1, make injury of birth canal and postpartum extravasated blood be able to timely removing, so can eliminate sooner lochia, accelerate sow Recovery.The duration of stages of labor and lochia is all reacted health status and the regulating power of sow reproductive system.This formula has the effect except evil leakage of obvious blood circulation promoting and enriching, anti-inflammatory postpartum to sow.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described, the scheme of embodiment described here, do not limit the present invention, one of skill in the art can make improvements and change according to spirit of the present invention, these described improvement and variation all should be considered as within the scope of the invention, and scope of the present invention and essence are limited by claim.Wherein the seed of cowherb, motherwort, dandelion, the Radix Astragali, Radix Angelicae Sinensis, hawthorn, cordate houttuynia, Ligusticum wallichii, Radix Rhapontici seu Radix Echinopsis are purchased from Tianjin Zhong Xin medicine company group, and quality is carried out by NF requirement standard, and VB1 is purchased from BASF AG.
Embodiment 1
Chinese medicine composition: 20 grams of the seeds of cowherb, 9 grams of motherworts, 10 grams of dandelions, 10 grams of the Radixs Astragali, 10 grams of Radix Angelicae Sinensis, 10 grams of hawthorn, 6 grams of cordate houttuynias, 5 grams of Ligusticum wallichiis, 8 grams of Radix Rhapontici seu Radix Echinopsis, 2 milligrams of VB1.
Preparation method:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then mixed according to formula;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 60min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) taking corn flour as carrier, corn flour is dried two hours in 105 DEG C of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the VB1 of formula Design evenly to mix, 65 DEG C of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight.
(6) complete according to above-mentioned steps successively processing and fabricating, then carry out packing with valve bag according to the concrete addition of formula, 4 DEG C of dry environments are preserved.
Embodiment 2
Chinese medicine composition: 60 grams of the seeds of cowherb, 20 grams of motherworts, 40 grams of dandelions, 30 grams of the Radixs Astragali, 40 grams of Radix Angelicae Sinensis, 30 grams of hawthorn, 12 grams of cordate houttuynias, 15 grams of Ligusticum wallichiis, 15 grams of Radix Rhapontici seu Radix Echinopsis, 1 milligram of VB.
Preparation method:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then mixed according to formula;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 80min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) taking corn flour as carrier, corn flour is dried two hours in 105 DEG C of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the VB1 of formula Design evenly to mix, 65 DEG C of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight.
(6) complete according to above-mentioned steps successively processing and fabricating, then carry out packing with valve bag according to the concrete addition of formula, 4 DEG C of dry environments are preserved.
Embodiment 3
The weight of Chinese medicine is: 50 grams of the seeds of cowherb, 10 grams of motherworts, 20 grams of dandelions, 20 grams of the Radixs Astragali, 30 grams of Radix Angelicae Sinensis, 10 grams of hawthorn, 10 grams of cordate houttuynias, 10 grams of Ligusticum wallichiis, 10 grams of Radix Rhapontici seu Radix Echinopsis, 1.5 milligrams of VB1.
Preparation method:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then mixed according to formula;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 70min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) taking corn flour as carrier, corn flour is dried two hours in 105 DEG C of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the VB1 of formula Design evenly to mix, 65 DEG C of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight.
(6) complete according to above-mentioned steps successively processing and fabricating, then carry out packing with valve bag according to the concrete addition of formula, 4 DEG C of dry environments are preserved.

Claims (2)

1. promote an additive for sow Recovery, it is characterized in that it is to have the raw material of following weight to make:
Seed of cowherb 20-60 gram, motherwort 9-20 gram, dandelion 10-40 gram, Radix Astragali 10-30 gram, Radix Angelicae Sinensis 10-40 gram, hawthorn 10-30 gram, cordate houttuynia 6-12 gram, Ligusticum wallichii 5-15 gram, Radix Rhapontici seu Radix Echinopsis 8-15 gram, corn flour, VB1 1-2 milligram; And undertaken by following step:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then mixed according to formula;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 60min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) taking corn flour as carrier, corn flour is dried two hours in 105 DEG C of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the VB1 of formula Design evenly to mix, 65 DEG C of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight;
(6) complete according to above-mentioned steps successively processing and fabricating, then carry out packing with valve bag according to the concrete addition of formula, 4 DEG C of dry environments are preserved.
2. additive claimed in claim 1 promotes the application in sow Recovery medicine in preparation; Wherein said sow Recovery refers to the lactagogue lactogenesis of first week point puerperium sow, blood circulation promoting and enriching, and anti-inflammatory, except evil leakage, is repaired injury of birth canal.
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