CN103211117B - Additive for promoting sow mammogenesis and preventing miscarriages as well as preparation method and application thereof - Google Patents
Additive for promoting sow mammogenesis and preventing miscarriages as well as preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses an additive for promoting sow mammogenesis and preventing miscarriages as well as a preparation method and application of the additive. The additive comprises the following traditional Chinese medicinal materials by weight: 10-40g of bighead atractylodes rhizome, 10-30g of astragalus, 15-35g of kudzuvine root, 6-12g of pawpaw, 8-15g of colored malt and 10-100mg of isoflavone. The invention further discloses application of the additive in preparing a medicine for improving the digestive function of the sow, promoting sow mammogenesis and preventing miscarriages. According to the additive, the experimental result proves that the additive can effectively promote the digestive function of the sow at the pregnancy period on the 90-107th days, promote sow mammogenesis and prevent miscarriages, and a good foundation is laid for the sow in the antepartum period.
Description
Technical field
The invention belongs to pannage additive technology field, relate to a kind of raising swinery production efficiency, the method that reduces production costs, more specifically say a kind of applicable sow of having added specific traditional Chinese medicine ingredients in perinatal period to swinery feed addictive of the different phase of during oestrus and preparation method thereof and application again after wean.
Background technology
In Swine Production process, how to enhance productivity, reduce production costs, be the target that pig industry is pursued always.The enterprise of more and more raising pigs has recognized that the importance of cost management, how cost is effectively managed, and is our common realistic problem of paying close attention to.The cost of pig industry mainly consists of several respects such as production efficiency of feed cost use, place colony house and personal management expense and swinery at present.Except reducing feed and production management cost, improve swinery production efficiency and become one of important channel reducing production costs.Therefore, people are placed on the research emphasis reducing production costs to improve in swinery production efficiency.China live pig produces and compares with animal husbandry developed country, also has larger gap.As developed country sow is produced 2.4 nests per year, China sow is produced only 2.0 nests per year; Every, developed country delivers pork pig sow year for sale more than 22, and only 16, China.Swinery production efficiency is mainly determined by boar production efficiency and pig-breeding level.The height of sow production efficiency is the basis that determines economic benefit.If providing pork pig number to bring up to 22 by current 16 in sow year, the cost of breeding part will reduce 37.5%.
The factor that affects sow production efficiency mainly contains the survival rate of annual output nest number, nest litter size and the piglet of sow.This is further analyzed, can be divided into the number of live birth and annual every Farrowing nest number.Not being both of annual every Farrowing nest number causes annual every sow between different pig farms to give birth to the different most important factors of number pigs born.Adjusting and optimize the parity structure of feeding mother pig, the breeding cycle of shortening multiparity sow, is to improve sow production efficiency, realizes the key measure of the high farrowing of sow, high benefit.Impact year childbirth nest number because have gestational period length, lactation number of days and nonproductive number of days.Nonproductive number of days refers to each breeding cycle or annual central sow or sow pig neither the pregnant number of days of non-lactation again.Be considered to affect the index of reproducting herd production efficiency most critical.This is not that nest litter size and Preweaning death rate are just inessential, but it is more much more difficult than nonproductive number of days to change nest litter size.
The gestational period, length was relatively fixing, and therefore shortening nonpregnant phase number of days just becomes the key point of enhancing productivity.Conventionally, adopt the method Shortening lactation period of early weaning, ultra-early weaning, thereby shorten nonpregnant number of days, sow just can oestrus tens days postpartum again, but according to domestic current cultivation level, employing ultra-early weaning piglet nurture difficulty strengthens, management condition requires strictly, sow recovery is more difficult.So also mainly adopt the mode of wean in 21-35 days postpartum in actual production.Generally speaking, be generally 28d lactation period, from wean to the number of days of breeding again, can be within 10d, and be on average 114d period of pregnancy, its scope is at 112～116d.If period of pregnancy, lactation period, nonproductive number of days are respectively 114d, 28d and 10d so.Therefore a broad sow can produce 2.4 tires every year in theory.In fact, the annual output tire number of the most of pig farms of China sow is at 1.9～2.0 tires.Reason is that the nonproductive number of days of sow is long.At present we with annual product 2.2 tires as the target of improving.The nonproductive number of days that like this, how to shorten sow just becomes the research emphasis that improves sow reproductive efficiency.
Summary of the invention
An object of the present invention is to disclose a kind of sow mammogenesis and additive of preventing miscarriage of promoting.
Another object of the present invention is its preparation method that discloses additive.
A further object of the present invention is to disclose the application of Chinese medicine additive in promotion sow mammogenesis and aspect preventing miscarriage.
For achieving the above object, the invention discloses following technology contents;
Promote sow mammogenesis and an additive of preventing miscarriage, it is characterized in that it is comprised of the Chinese medicine of following weight:
Bighead atractylodes rhizome 10-40 gram, Radix Astragali 10-30 gram, root of kudzu vine 15-35 gram;
Pawpaw 6-12 gram, coloured malt 8-15 gram, isoflavones 10-100 milligram.
Additive of the present invention, preferably the weight of Chinese medicine is: 30 grams of the bighead atractylodes rhizomes, 20 grams of the Radixs Astragali, 20 grams of the roots of kudzu vine, 10 grams of pawpaws, 10 grams of coloured malts, 20 milligrams of isoflavones.
The present invention further discloses the preparation method of additive, it is characterized in that being undertaken by following step:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then according to formula, mixed;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 60min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) take corn flour as carrier, corn flour is dried two hours in 105 ℃ of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the isoflavones of formula Design evenly to mix, 65 ℃ of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight.
(6) according to above-mentioned steps successively processing and fabricating, complete, then with valve bag, according to the concrete addition of formula, carry out packing, 4 ℃ of dry environments are preserved.
The present invention's Chinese medicine effect used is as follows with effect:
Take the bighead atractylodes rhizome as main, beneficial stomach invigorating the spleen, hidroschesis is antiabortive, conditioning sow stomach machine, take the Radix Astragali as auxiliary energy, invigorating qi for strengthening superficies, anti-inflammation, strengthens immunity of organisms, and two taste medicines are used in conjunction with and can prevent general obstetrics disease, root of kudzu vine pawpaw all has the mammogenesis of promotion effect, and kudzu root nutrient cardiac muscle, lifts gas lift sun, the pawpaw ventilation of invigorating blood circulation, stomach strengthening and digestion promoting, all can improve sow immunocompetence.With Fructus Hordei Germinatus for making, promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite.
As the product that promotes sow mammogenesis and the additive of preventing miscarriage, the composition of Chinese herb feed additive and dosage are two essence marrow of additive.In many cases, even the prescription that same medicine forms, because the consumption of each ingredients is different, its medication effect is also different.The selected formula of the present invention is to be mainly applied to promote the mammogenesis of antenatal pregnant 90-107 days sows and prevent miscarriage.Therefore, the effect of compound additive of the present invention is that the acting in conjunction by all the components in prescription embodies, and therefore selecting the proportioning of specific raw material and definite stock yard is the key of additive.
Principle below having followed aspect the proportioning of the determining of raw material, stock yard:
(1) this test basis Chinese veterinarian theory and Chinese herbal medicine combination principle carry out prescription, each taste Chinese herbal medicine is carried out to oxicity analysis and screening, each taste Chinese herbal medicine of selecting is actual nontoxic level Chinese herbal medicine, adhere rigidly to drug matching principle in compatibility process, avoid the incompatibility of Chinese medicine " eighteen incompatibilities, nineteen counteraction ", and use for reference the compatibility theory of traditional ripe proved recipe.The use amount that in prescription, each medicine addition is all recommended experience prescription in addition and traditional prescription with reference to " China's book on Chinese herbal medicine ".
(2) in palatability testing process, sow is carried out to the quintuple of the maximum addition of formal test and add, feed and within seven days, do not find any bad reaction or toxic reaction.
(3) finally determine: 30 grams of the bighead atractylodes rhizomes, 20 grams of the Radixs Astragali, 20 grams of the roots of kudzu vine, 10 grams of pawpaws, 10 grams of coloured malts, 20 milligrams of isoflavones.
The present invention further discloses additive improves sow digestive function in preparation, promotes the application in sow mammogenesis and anti-abortion medicine.Improving sow digestive function mainly refers to: promote the digestive function of pregnant 90-107 days sows, promote the growth of sow mammary gland, for sow is in the antenatal good basis of laying.
The present invention selects that Breeding date is close, reproductive performance, body condition be without the white sow of the purebred length of multiparity (a pig kind that originates in Denmark, English name: Landrace, is called " Landrace " old China hand) of significant difference, is divided at random test group and control group.According to emphasis and traditional Chinese medicine theory and the proved recipe of regulation and control, Chinese prescription is determined in screening.
The more detailed preparation method of the present invention is as follows:
(1) material of experiment: the bighead atractylodes rhizome, the Radix Astragali, the root of kudzu vine, pawpaw (papaya that produce in Guangdong), coloured malt are purchased from Tianjin Zhong Xin medicine company group, and quality is carried out by NF requirement standard.Isoflavones is purchased from Dalian Ao Pu animal pharmaceutical estate Co., Ltd.
(2) method of experiment:
1) use the electronic scale that minimum scale is 0.2g, each taste Chinese herbal medicine is weighed according to the addition of formula Design, then according to formula, mix.
2) ratio of water: Chinese medicine=5:1 is soaked the Chinese herbal medicine 60min of compatibility, and in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters.The dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters.
3) merging filtrate, heating is concentrated into medicine, liquor ratio is 1:1, and 1ml liquid is equivalent to crude drug 1g, notes stirring, and can not occur enduring paste phenomenon.
4) take corn flour as carrier, corn flour is dried two hours in 105 ℃ of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the isoflavones of formula Design evenly to mix, 65 ℃ of drying in oven, obtain the finished product herbal prescription identical with crude drug in whole weight.
According to above-mentioned steps successively processing and fabricating, complete, then with valve bag, according to the concrete addition of formula, carry out packing, 4 ℃ of dry environments are preserved.
Test method of the present invention is as follows:
Basal diet and trophic level
According to the trophic level in the large scale of pig farm actual production of Tianjin in contrast; using the level of U.S. NRC pig nutritional requirements (1998), the suggestion of Chinese milking sow feeding standard (1987) nutritional need as benchmark simultaneously; basal diet formula and nutrient composition content during definite test sow gestation, in Table 1.
Table 1 in-pig basal diet composition and nutrient composition content
| Raw material | Proportioning (%) | Nutritive index | Nutrient content |
| Corn | 65.00 | Digestible energy (MJ/kg) | 11.40 |
| Dregs of beans | 14.00 | Crude protein (%) | 14.19 |
| Wheat bran | 17.00 | Lysine (%) | 0.70 |
| Premix | 4.00 | Ca（%） | 1.13 |
| ? | ? | P（%） | 0.47 |
Remarks:
1. in nutritional labeling, crude protein, calcium, phosphorus are measured value, and all the other are calculated value, and the basal diet of two groups is identical.
2. the existing formula in direct application test place, measures conventional nutrient composition content in feed.
3. premix: honest feed corporation,Ltd produces by Tianjin.
20 sows are divided into 2 processed group at random, and each processed group is established 10 repetitions, and each repeats 1.
Processing 1 is control group, the conventional daily ration of feeding; Processing 2 is test group, uses the compound Chinese herbal medicine additive of design above at pregnant 90-107 days.16 days experimental periods.Test pig is taked the limit method of raising, and every morning 4 of 5:30 point and afternoons respectively feed once, and trial drug Feeding time is 5:30 point in morning, carry out with feeding for the first time simultaneously, by trial drug mix in feed hello to.
(3) experimental result: Chinese herbal medicine compound additive to the effect of fetus care in middle of pregnant 90-108 days sow in Table 2.
The effect of fetus care in middle of table 2. Chinese herbal medicine compound additive to sow
From table 2., total litter size of test group and control group is basically identical, indifference.But test group is after having added the composite Chinese herbal additive with anti-abortional effect, and qualified piglet number is apparently higher than control group (P<0.05); Still birth rate and weak young rate are also starkly lower than control group (P<0.05).
(4) conclusion: the bighead atractylodes rhizome contains multiple Ginkgolide Component and has immunocompetent mannosan AM-3, has and strengthens body immunity, diuresis, anti-oxidant, calm, the uterine smooth muscle that relaxes, antiabortive effect.Be aided with again the Radix Astragali, invigorating qi for strengthening superficies, anti-inflammation, strengthens immunity of organisms, two taste medicines are used in conjunction with and can prevent general obstetrics disease, and root of kudzu vine pawpaw all has the mammogenesis of promotion effect, and kudzu root nutrient cardiac muscle, lift gas lift sun, the pawpaw ventilation of invigorating blood circulation, stomach strengthening and digestion promoting, all can improve sow immunocompetence.Coloured malt has promote qi circulation digestion promoting, the effect of spleen benefiting and stimulating the appetite.Above Chinese herbal medicine adds the isoflavones with estrogen-like action, and the composite additive of composition has good anti-abortional effect.
The specific embodiment
Below in conjunction with embodiment, the present invention is described, the scheme of embodiment described here, do not limit the present invention, one of skill in the art can make improvements and change according to spirit of the present invention, these described improvement and variation all should be considered as within the scope of the invention, and scope of the present invention and essence are limited by claim.Wherein the bighead atractylodes rhizome, the Radix Astragali, the root of kudzu vine, pawpaw (papaya that produce in Guangdong), coloured malt are purchased from Tianjin Zhong Xin medicine company group, and quality is carried out by NF requirement standard.Isoflavones is purchased from Dalian Ao Pu animal pharmaceutical estate Co., Ltd.
Embodiment 1.
Chinese medicine forms: 10 grams of the bighead atractylodes rhizomes, 10 grams of the Radixs Astragali, 15 grams of the roots of kudzu vine; 6 grams of pawpaws, 8 grams of coloured malts, 10 milligrams of isoflavones.
Preparation method:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then according to formula, mixed;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 60min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) take corn flour as carrier, corn flour is dried two hours in 105 ℃ of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the isoflavones of formula Design evenly to mix, 65 ℃ of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight.
(6) according to above-mentioned steps successively processing and fabricating, complete, then with valve bag, according to the concrete addition of formula, carry out packing, 4 ℃ of dry environments are preserved.
Embodiment 2
Chinese medicine forms: 40 grams of the bighead atractylodes rhizomes, 30 grams of the Radixs Astragali, 35 grams of the roots of kudzu vine; 12 grams of pawpaws, 15 grams of coloured malts, 80 milligrams of isoflavones.
Preparation method:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then according to formula, mixed;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 80min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) take corn flour as carrier, corn flour is dried two hours in 105 ℃ of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the isoflavones of formula Design evenly to mix, 65 ℃ of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight.
(6) according to above-mentioned steps successively processing and fabricating, complete, then with valve bag, according to the concrete addition of formula, carry out packing, 4 ℃ of dry environments are preserved.
Embodiment 3
The weight of Chinese medicine is: 30 grams of the material bighead atractylodes rhizomes, 20 grams of the Radixs Astragali, 20 grams of the roots of kudzu vine, 10 grams of pawpaws, 10 grams of coloured malts, 20 milligrams of isoflavones.
Preparation method:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then according to formula, mixed;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 70min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) take corn flour as carrier, corn flour is dried two hours in 105 ℃ of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the isoflavones of formula Design evenly to mix, 65 ℃ of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight.
(6) according to above-mentioned steps successively processing and fabricating, complete, then with valve bag, according to the concrete addition of formula, carry out packing, 4 ℃ of dry environments are preserved.
Claims (4)
1. promote sow mammogenesis and an additive of preventing miscarriage, it is characterized in that it is comprised of following Chinese medicine:
Bighead atractylodes rhizome 10-40 gram, Radix Astragali 10-30 gram, root of kudzu vine 15-35 gram;
Pawpaw 6-12 gram, coloured malt 8-15 gram, isoflavones 10-100 milligram, and prepare by following step:
(1) each taste Chinese herbal medicine is weighed according to the addition of formula Design, then according to formula, mixed;
(2) adopt the water that parts by weight are 5:1: Chinese medicine ratio is soaked the Chinese herbal medicine 60min of compatibility, in electric pot, heating is boiled with high heat, then changes slow fire into, continues to decoct 60min, stirs while hot, filters;
(3) dregs of a decoction again boiling once, the water yield was not for there to be powder, boiling time 30min, filters;
(4) merging filtrate, heating is concentrated into medicine, liquid volume ratio is 1:1;
(5) take corn flour as carrier, corn flour is dried two hours in 105 ℃ of baking ovens, remove the enzyme in corn flour, mix with liquid after cooling, after adding again the isoflavones of formula Design evenly to mix, 65 ℃ of drying in oven, obtain the Chinese herb feed additive identical with crude drug in whole weight;
(6) according to above-mentioned steps successively processing and fabricating, complete, then with valve bag, according to the concrete addition of formula, carry out packing, 4 ℃ of dry environments are preserved.
2. described in claim 1, promote sow mammogenesis and the additive of preventing miscarriage, the weight of wherein said Chinese medicine is: 30 grams of the bighead atractylodes rhizomes, 20 grams of the Radixs Astragali, 20 grams of the roots of kudzu vine, 10 grams of pawpaws, 10 grams of coloured malts, 20 milligrams of isoflavones.
3. the additive that promotes sow mammogenesis described in claim 1 and prevent miscarriage improves sow digestive function in preparation, promotes sow mammary gland secondary to grow the application in medicine.
4. the additive that promotes sow mammogenesis described in claim 3 and prevent miscarriage improves sow digestive function in preparation, promotes sow mammary gland secondary to grow the application in medicine, and wherein said promotion sow mammogenesis and preventing miscarriage refers to: the sow of antenatal pregnant 90-107 days.
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104351584B (en) * | 2014-12-08 | 2016-09-14 | 湖南泰丰动物药业有限公司 | A kind of feed additive reducing somatic number in milk and application thereof |
| CN104543519A (en) * | 2014-12-24 | 2015-04-29 | 广东恒兴饲料实业股份有限公司 | Additive premix for Luchuan sow in lactation period and application method of additive premix |
| CN105076681A (en) * | 2015-08-05 | 2015-11-25 | 马宗彦 | Pregnant sow feed and preparation method thereof |
| CN113508871A (en) * | 2021-08-09 | 2021-10-19 | 黑龙江省农业科学院畜牧研究所 | Natural plant additive for improving reproductive performance of sows and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1518417A (en) * | 2001-06-21 | 2004-08-04 | 协和发酵工业株式会社 | Process for producing plant extract containing plant powder |
| CN101297681A (en) * | 2008-06-16 | 2008-11-05 | 王海东 | Feedstuff additive for improving milk production and quality containing kudzu root as main component |
| CN102524583A (en) * | 2012-01-19 | 2012-07-04 | 江西双胞胎实业有限公司 | Composite pig feed additive for preventing diarrhea of pigs |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1518417A (en) * | 2001-06-21 | 2004-08-04 | 协和发酵工业株式会社 | Process for producing plant extract containing plant powder |
| CN101297681A (en) * | 2008-06-16 | 2008-11-05 | 王海东 | Feedstuff additive for improving milk production and quality containing kudzu root as main component |
| CN102524583A (en) * | 2012-01-19 | 2012-07-04 | 江西双胞胎实业有限公司 | Composite pig feed additive for preventing diarrhea of pigs |
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