CN103110753A - Buccal tablet for improving sleep and preparation process thereof - Google Patents
Buccal tablet for improving sleep and preparation process thereof Download PDFInfo
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- CN103110753A CN103110753A CN2013100358619A CN201310035861A CN103110753A CN 103110753 A CN103110753 A CN 103110753A CN 2013100358619 A CN2013100358619 A CN 2013100358619A CN 201310035861 A CN201310035861 A CN 201310035861A CN 103110753 A CN103110753 A CN 103110753A
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- concentrated juice
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- surinam
- vitis viniferae
- menthol
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Abstract
The invention discloses a buccal tablet for improving sleep. The buccal tablet consists of raw materials and auxiliary materials, wherein the raw materials comprise surinam cherry concentrated juice, grape seed concentrated juice, picrorhizae concentrated juice and cordyceps powder, and the auxiliary materials comprise seabuckthorn and menthol. The preparation process comprises the following steps of: firstly, treating the raw materials, mixing the surinam cherry concentrated juice, the grape seed concentrated juice, the picrorhizae concentrated juice and the cordyceps powder, adding seabuckthorn and menthol and stirring to obtain a uniform mixture, and then granulating, tabletting and packaging to obtain the buccal tablet. The buccal tablet adjusts and restores the circadian clock, can effectively nourish brain cells damaged due to insomnia after a long-term use, improves brain blood-oxygen exchange, nourishes blood and concentrate, enhances the sleep quality and improves the insomnia problem thoroughly.
Description
Technical field
The present invention relates to the health food technology field, be specifically related to a kind of buccal tablet and preparation technology thereof who improves sleep.
Background technology
Market is existing, and to improve the sleep medicine be the Western medicine of effective ingredient mainly with melatonin and add other adjuvants and form, and mainly with swallowing or capsule form exists.The Western medicine medicine is many with different side effect, and safety is relatively poor, and dependency is also stronger, and the class medicine of swallowing absorbs by the intestines and stomach and bring into play usedly, and utilization ratio of drug is relatively poor.And the present invention uses Surinam's Fructus Pruni pseudocerasi to add multiple rare Chinese medicine composition as primary raw material, safe, and employing is sucked mode and is played effectiveness, pass through buccal absorption, without the intestines and stomach absorption thereby non-stimulated to the intestines and stomach, avoided simultaneously the decomposition destruction of the digestive system such as gastric acid to effective ingredient, utilization ratio of drug is higher.In addition, it is base material that the present invention adopts menthol, not sugary and other additives, and diabetics also can relievedly be taken.
Summary of the invention
In order to overcome above-mentioned existing technical disadvantages, the object of the present invention is to provide a kind of buccal tablet and preparation technology thereof who improves sleep, have advantages of determined curative effect, safe ready.
In order to achieve the above object, the technical scheme taked of the present invention is:
A kind of buccal tablet that improves sleep, formed by stock and adjunct, the stock and adjunct mass ratio is 6:4, raw material by Cordyceps powder, Surinam's Fructus Pruni pseudocerasi concentrated juice, Semen Vitis viniferae concentrated juice, Rhizoma Picrorhizae concentrated juice according to 6:2:2:1(g/ml) composition of proportions, adjuvant is made of Fructus Hippophae and menthol, and Fructus Hippophae and menthol account for respectively tablet quality 30% and 10%, and the concentration of Surinam's Fructus Pruni pseudocerasi concentrated juice is 65%, the Semen Vitis viniferae concentrated juice concentration be 60%, the Rhizoma Picrorhizae concentrated juice concentration be 20%.
A kind of preparation technology who improves the buccal tablet of sleep comprises the following steps:
The first step, raw material is processed
1, Surinam cherry is extracted:
A gets Surinam's cherry kernel removing dry fruit, adds water in the 1:2 ratio and soaks 20-30min in 80-90 ℃;
B heats to 70-80 ℃, the broken 15-20min and remove seed of pulling an oar, and the beater aperture is less than 2mm;
C adds 60% ethanol with 1:2.0~2.5 ratio lixiviate 24h;
D filters with 40 eye mesh screens;
E to filtrate with the centrifugal 5min of 3500r/min;
Reclaim ethanol in the ethanol recovery tower at F vacuum-55-65 ℃ of 0.08Mpa temperature;
G obtains soluble solid content and reaches 15% filtrate;
H by the vacuum decompressioning and concentrating tank concentrating under reduced pressure after the concentrated fruit juice soluble solid content reach 65% to 70%;
2, Semen Vitis viniferae extracts
Pretreatment of raw material pulverizes and sieves 20 orders, then lixiviate, and every 100g Semen Vitis viniferae is the 60%-70% alcohol steep with 700ml concentration, then vacuum-concentrcted, vacuum-0.08Mpa, 37 ℃ of temperature are to obtaining feed liquid relative density 1.2g/cm
3, defat with petroleum ether 6h purifies with 50% ethyl acetate, solid-liquid ratio is 1:3 (g/ml), mixing time 15min, extraction time 3 times, concentrated at last, macroporous resin adsorption, with 40% alcoholic solution eluting, the Semen Vitis viniferae concentrated juice concentration reach 60%;
3, Rhizoma Picrorhizae extracts
Pretreatment of raw material is cleaned, then decocts, and the per kilogram Rhizoma Picrorhizae adds water 3000ml and decocts 30min, vacuum-concentrcted then, and vacuum-0.08Mpa, 35 ℃ of temperature are to obtaining feed liquid relative density 1.15g/cm
3
4, Cordyceps is pulverized
Getting Cordyceps pulverizing 200 orders sieves;
Second step, with Cordyceps powder, Surinam's Fructus Pruni pseudocerasi concentrated juice, Semen Vitis viniferae concentrated juice, Rhizoma Picrorhizae concentrated juice according to solid-liquid ratio 6:2:2:1(g/ml) mix, and add Fructus Hippophae and menthol, Fructus Hippophae and menthol account for respectively material gross mass 30% and 10%, stir 2h with 300r/min under room temperature, material is uniformly mixed;
The 3rd step, granulate, the even compound of material is made the granule that diameter is 250um;
In the 4th step, tabletting is pressed into sheet with granule;
In the 5th step, the sheet that presses is packed.
Advantage of the present invention is: adjust and recover biological clock round the clock, containing the rare Chinese medicine nourishing ingredients such as Rhizoma Picrorhizae, Cordyceps, life-time service can effectively nourish because having a sleepless night impaired brain cell, improve the exchange of brain blood oxygen, nourish blood meticulously, sleep quality is improved, and the insomnia problem is thoroughly improved.
The specific embodiment
Below in conjunction with embodiment, preparation technology of the present invention is described in detail.
Embodiment 1
A kind of preparation technology who improves the buccal tablet of sleep comprises the following steps:
The first step, raw material is processed
1, Surinam cherry is extracted:
A gets Surinam's cherry kernel removing dry fruit, adds water with the 1:2 ratio and soaks 30min in 80 ℃;
B heats to 70 ℃, the broken 15min and remove seed of pulling an oar, and the beater aperture is less than 2mm;
C adds 60% ethanol with 1:2 ratio lixiviate 24h;
D filters with 40 eye mesh screens;
E to filtrate with the centrifugal 5min of 3500r/min;
Reclaim ethanol in the ethanol recovery tower at F vacuum-55 ℃ of 0.08Mpa temperature;
G obtains soluble solid content and reaches 15% filtrate;
H by the vacuum decompressioning and concentrating tank concentrating under reduced pressure after the concentrated fruit juice soluble solid content reach 65% to 70%;
2, Semen Vitis viniferae extracts
Pretreatment of raw material pulverizes and sieves 20 orders, lixiviate, and every 100g Semen Vitis viniferae is the 60%-70% alcohol steep with 700ml concentration, vacuum-concentrcted, vacuum-0.08Mpa, 37 ℃ of temperature are to obtaining feed liquid relative density 1.2g/cm
3, defat with petroleum ether 6h purifies with 50% ethyl acetate, and solid-liquid ratio is 1:3(g/ml), mixing time 15min, extraction time 3 times, after extraction, purity brings up to 66% by 40%, and is concentrated, macroporous resin adsorption, with 40% alcoholic solution eluting, the Semen Vitis viniferae concentrated juice concentration reach 60%;
The alcohol reflux extraction: concentration of alcohol is 70%, and extracting temperature is 50 ℃, and solid-liquid ratio is l:7 (g/ml), and extraction time is 30min, and extraction time is 3 times;
3, Rhizoma Picrorhizae extracts
Pretreatment of raw material is cleaned, and decocts, and the per kilogram Rhizoma Picrorhizae adds water 3000ml and decocts 30min, vacuum-concentrcted, and vacuum-0.08Mpa, 35 ℃ of temperature are to obtaining feed liquid relative density 1.15g/cm
3
4, Cordyceps is pulverized
Getting Cordyceps pulverizing 200 orders sieves;
Second step, with Cordyceps powder, Surinam's Fructus Pruni pseudocerasi concentrated juice, Semen Vitis viniferae concentrated juice, Rhizoma Picrorhizae concentrated juice according to solid-liquid ratio 6:2:2:1(g/ml) mix, and add Fructus Hippophae and menthol, Fructus Hippophae and menthol account for respectively material gross mass 30% and 10%, stir 2h with 300r/min under room temperature, material is uniformly mixed;
The 3rd step, granulate, the even compound of material is made the granule that diameter is 250um;
In the 4th step, tabletting is pressed into sheet with granule;
In the 5th step, the sheet that presses is packed.
Embodiment 2
A kind of preparation technology who improves the buccal tablet of sleep comprises the following steps:
The first step, raw material is processed
1, Surinam's Fructus Pruni pseudocerasi extracts:
A gets Surinam's cherry kernel removing dry fruit, adds water with the 1:2 ratio and soaks 20min in 90 ℃;
B heats to 80 ℃, the broken 20min and remove seed of pulling an oar, and the beater aperture is less than 2mm;
C adds 60% ethanol with 1:2 ratio lixiviate 24h;
D filters with 40 eye mesh screens;
E to filtrate with the centrifugal 5min of 3500r/min;
Reclaim ethanol in the ethanol recovery tower at F vacuum-65 ℃ of 0.08Mpa temperature;
G obtains soluble solid content and reaches 15% filtrate;
H by the vacuum decompressioning and concentrating tank concentrating under reduced pressure after the concentrated fruit juice soluble solid content reach 65% to 70%;
2, Semen Vitis viniferae extracts
Pretreatment of raw material pulverizes and sieves 20 orders, lixiviate, and every 100g Semen Vitis viniferae is 60% alcohol steep with 700ml concentration, vacuum-concentrcted, vacuum-0.08Mpa, 37 ℃ of temperature are to obtaining feed liquid relative density 1.2g/cm
3, defat with petroleum ether 6h purifies with 50% ethyl acetate, solid-liquid ratio is 1:3(g/ml), mixing time 15min, extraction time 3 times, concentrated, macroporous resin adsorption, with 40% alcoholic solution eluting, the Semen Vitis viniferae concentrated juice concentration reach 60%;
Ultrasonic assisted Leaching lifting manipulation: ultrasonic power is 120W, and concentration of alcohol is 40%, and solid-liquid ratio is l:30 (g/ml), and extracting temperature is 40 ℃, and ultrasonic time is 10min, and extraction time is 1 time;
3, Rhizoma Picrorhizae extracts
Pretreatment of raw material is cleaned, and decocts, and the per kilogram Rhizoma Picrorhizae adds water 3000ml and decocts 30min, vacuum-concentrcted, and vacuum-0.08Mpa, 35 ℃ of temperature are to obtaining feed liquid relative density 1.15g/cm
3
4, Cordyceps is pulverized
Getting Cordyceps pulverizing 200 orders sieves;
Second step, with Cordyceps powder, Surinam's Fructus Pruni pseudocerasi concentrated juice, Semen Vitis viniferae concentrated juice, Rhizoma Picrorhizae concentrated juice according to solid-liquid ratio 6:2:2:1(g/ml) mix, and add Fructus Hippophae and menthol, Fructus Hippophae and menthol account for respectively material gross mass 30% and 10%, stir 2h with 300r/min under room temperature, material is uniformly mixed;
The 3rd step, granulate, the even compound of material is made the granule that diameter is 250um;
In the 4th step, tabletting is pressed into sheet with granule;
In the 5th step, the sheet that presses is packed.
Embodiment 3
A kind of preparation technology who improves the buccal tablet of sleep comprises the following steps:
The first step, raw material is processed
1, Surinam's Fructus Pruni pseudocerasi extracts:
A gets Surinam's cherry kernel removing dry fruit, adds water in the 1:2 ratio and soaks 30min in 80 ℃;
B heats to 80 ℃, the broken 20min and remove seed of pulling an oar, and the beater aperture is less than 2mm;
C adds 60% ethanol with 1:2.5 ratio lixiviate 24h;
D filters with 40 eye mesh screens;
E to filtrate with the centrifugal 5min of 3500r/min;
Reclaim ethanol in the ethanol recovery tower at F vacuum-65 ℃ of 0.08Mpa temperature;
G obtains soluble solid content and reaches 15% filtrate;
H by the vacuum decompressioning and concentrating tank concentrating under reduced pressure after the concentrated fruit juice soluble solid content reach 65% to 70%;
2, Semen Vitis viniferae extracts
Pretreatment of raw material pulverizes and sieves 20 orders, lixiviate, and every 100g Semen Vitis viniferae is 70% alcohol steep with 700ml concentration, vacuum-concentrcted, vacuum-0.08Mpa, 37 ℃ of temperature are to obtaining feed liquid relative density 1.2g/cm
3, defat with petroleum ether 6h purifies with 50% ethyl acetate, solid-liquid ratio is 1:3(g/ml), mixing time 15min, extraction time 3 times, concentrated, macroporous resin adsorption, with 40% alcoholic solution eluting, the Semen Vitis viniferae concentrated juice concentration reach 60%;
The microwave-assisted extraction: solid-liquid ratio is 1:18(g/ml), concentration of alcohol be 60%, microwave action time 50s, backflow lixiviate 30min in the water bath with thermostatic control of 50 ℃, extraction time is 1 time;
3, Rhizoma Picrorhizae extracts
Pretreatment of raw material is cleaned, and decocts, and the per kilogram Rhizoma Picrorhizae adds water 3000ml and decocts 30min, vacuum-concentrcted, and vacuum-0.08Mpa, 35 ℃ of temperature are to obtaining feed liquid relative density 1.15g/cm
3
4, Cordyceps is pulverized
Getting Cordyceps pulverizing 200 orders sieves;
Second step, with Cordyceps powder, Surinam's Fructus Pruni pseudocerasi concentrated juice, Semen Vitis viniferae concentrated juice, Rhizoma Picrorhizae concentrated juice according to solid-liquid ratio 6:2:2:1(g/ml) mix, and add Fructus Hippophae and menthol, Fructus Hippophae and menthol account for respectively material gross mass 30% and 10%, stir 2h with 300r/min under room temperature, material is uniformly mixed;
The 3rd step, granulate, the even compound of material is made the granule that diameter is 250um;
In the 4th step, tabletting is pressed into sheet with granule;
In the 5th step, the sheet that presses is packed.
Claims (2)
1. buccal tablet that improves sleep, formed by stock and adjunct, it is characterized in that: the stock and adjunct mass ratio is 6:4, raw material by Cordyceps powder, Surinam's Fructus Pruni pseudocerasi concentrated juice, Semen Vitis viniferae concentrated juice, Rhizoma Picrorhizae concentrated juice according to 6:2:2:1(g/ml) composition of proportions, adjuvant is made of Fructus Hippophae and menthol, Fructus Hippophae and menthol account for respectively tablet quality 30% and 10%, the concentration of Surinam's Fructus Pruni pseudocerasi concentrated juice is 65%, the Semen Vitis viniferae concentrated juice concentration be 60%, the Rhizoma Picrorhizae concentrated juice concentration be 20%.
2. a kind of preparation technology who improves the buccal tablet of sleep according to claim 1, is characterized in that, comprises the following steps:
The first step, raw material is processed
1), Surinam cherry is extracted:
A gets Surinam's cherry kernel removing dry fruit, adds water in the 1:2 ratio and soaks 20-30min in 80-90 ℃;
B heats to 70-80 ℃, the broken 15-20min and remove seed of pulling an oar, and the beater aperture is less than 2mm;
C adds 60% ethanol with 1:2.0~2.5 ratio lixiviate 24h;
D filters with 40 eye mesh screens;
E to filtrate with the centrifugal 5min of 3500r/min;
Reclaim ethanol in the ethanol recovery tower at F vacuum-55-65 ℃ of 0.08Mpa temperature;
G obtains soluble solid content and reaches 15% filtrate;
H by the vacuum decompressioning and concentrating tank concentrating under reduced pressure after the concentrated fruit juice soluble solid content reach 65% to 70%;
2), Semen Vitis viniferae extracts
Pretreatment of raw material pulverizes and sieves 20 orders, then lixiviate, and every 100g Semen Vitis viniferae is the 60%-70% alcohol steep with 700ml concentration, then vacuum-concentrcted, vacuum-0.08Mpa, 37 ℃ of temperature are to obtaining feed liquid relative density 1.2g/cm
3, defat with petroleum ether 6h purifies with 50% ethyl acetate, solid-liquid ratio is 1:3 (g/ml), mixing time 15min, extraction time 3 times, concentrated at last, macroporous resin adsorption, with 40% alcoholic solution eluting, the Semen Vitis viniferae concentrated juice concentration reach 60%;
3), Rhizoma Picrorhizae extracts
Pretreatment of raw material is cleaned, then decocts, and the per kilogram Rhizoma Picrorhizae adds water 3000ml and decocts 30min, vacuum-concentrcted then, and vacuum-0.08Mpa, 35 ℃ of temperature are to obtaining feed liquid relative density 1.15g/cm
3
4), Cordyceps is pulverized
Getting Cordyceps pulverizing 200 orders sieves;
Second step, with Cordyceps powder, Surinam's Fructus Pruni pseudocerasi concentrated juice, Semen Vitis viniferae concentrated juice, Rhizoma Picrorhizae concentrated juice according to solid-liquid ratio 6:2:2:1(g/ml) mix, and add Fructus Hippophae and menthol, Fructus Hippophae and menthol account for respectively material gross mass 30% and 10%, stir 2h with 300r/min under room temperature, material is uniformly mixed;
The 3rd step, granulate, the even compound of material is made the granule that diameter is 250um;
In the 4th step, tabletting is pressed into sheet with granule;
In the 5th step, the sheet that presses is packed.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103493939A (en) * | 2013-10-15 | 2014-01-08 | 北京绿源求证科技发展有限责任公司 | Sleeping-aid food-made tea granules for sleep improvement |
JP2019006717A (en) * | 2017-06-27 | 2019-01-17 | 花王株式会社 | Oral sleep improver |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101982164A (en) * | 2010-10-26 | 2011-03-02 | 浙江长生鸟珍珠生物科技有限公司 | Modified pearl cherry vitamin C sleeping mask and preparation method thereof |
CN102090684A (en) * | 2010-09-06 | 2011-06-15 | 山东好当家海洋发展股份有限公司 | Marine collagen peptide beverage and preparation method thereof |
CN102389133A (en) * | 2011-11-04 | 2012-03-28 | 陕西海升果业发展股份有限公司 | Process for producing cherry juice concentrate |
-
2013
- 2013-01-31 CN CN2013100358619A patent/CN103110753A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102090684A (en) * | 2010-09-06 | 2011-06-15 | 山东好当家海洋发展股份有限公司 | Marine collagen peptide beverage and preparation method thereof |
CN101982164A (en) * | 2010-10-26 | 2011-03-02 | 浙江长生鸟珍珠生物科技有限公司 | Modified pearl cherry vitamin C sleeping mask and preparation method thereof |
CN102389133A (en) * | 2011-11-04 | 2012-03-28 | 陕西海升果业发展股份有限公司 | Process for producing cherry juice concentrate |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103493939A (en) * | 2013-10-15 | 2014-01-08 | 北京绿源求证科技发展有限责任公司 | Sleeping-aid food-made tea granules for sleep improvement |
JP2019006717A (en) * | 2017-06-27 | 2019-01-17 | 花王株式会社 | Oral sleep improver |
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Application publication date: 20130522 |