CN103110527A - External preparation for spot treatment - Google Patents
External preparation for spot treatment Download PDFInfo
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- CN103110527A CN103110527A CN 201310057022 CN201310057022A CN103110527A CN 103110527 A CN103110527 A CN 103110527A CN 201310057022 CN201310057022 CN 201310057022 CN 201310057022 A CN201310057022 A CN 201310057022A CN 103110527 A CN103110527 A CN 103110527A
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- external preparation
- spot treatment
- treatment
- preparation
- mottle
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- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to an external preparation for spot treatment. The external preparation for spot treatment is characterized by containing hydroquinone, arbutin and oleuropein. The external preparation for spot treatment is beneficial to improve the permeability of capillary vessels of the skin and promotes subcutaneous circulation.
Description
Technical field
The invention belongs to cosmetic field, relate to a kind of external preparation for the treatment of mottle.
Background technology
The mottle traditional Chinese medical science is said genus " dusty face ", " chloasma " category, is a kind of common chromatopathy, is apt to occur in the women.Modern medicine thinks that Nervous and Mental Factors, Exposure to Sunlight, gestation, cosmetics improper use etc. are the main inducing of primary disease.Endocrine regulation, the little ecological disturbance of skin and radical damage are its main pathogenesis.Chinese medicine is thought, depression of liver-QI, strongly fragrant fire-transformation of a specified duration, the cloudy blood of burning, and obstruction of collaterals by blood stasis causes face qi-blood disharmony; Deficiency-weakness of spleen-QI, transporting are lost strong, can not change spermatogenesis little, and QI and blood can not be moistened in face; The pathological change such as insufficiency of kidney-YANG, deficiency of kidney-essence all can cause face generation mottle.It is long to add the sunshine-duration, easily causes melanin deposition, shows as generation and the intensification of mottle.
For its main pathology, smear as main take medicine for external use, suitably coordinates the methods such as oral medicine, massage by control in treatment for doctor trained in Western medicine, and medicine for external use commonly used has 3% Hydrochinone Cream etc. at present, and effect is unsatisfactory.Nowadays Chinese medicine more and more receives people's concern in the advantage for the treatment of in mottle, Chinese medicine by resolving blood stasis and dredging collateral, improve microcirculation, adjust endocrine, eliminate alluvial in body, thereby reach the purpose of speckle dispelling.
Summary of the invention
The present invention is directed to the deficiency that present speckle dispelling product exists, a kind of external preparation for the treatment of mottle is provided.
The present invention is achieved in that
The external preparation for the treatment of mottle, it is characterized in that: said preparation contains the raw material of following weight proportioning: hydroquinone 1-5, arbutin 10-20, oleuropein 10-20.Preferably, said preparation contains the raw material of following weight proportioning: hydroquinone 3, arbutin 15, oleuropein 15.
The specific embodiment
Embodiment 1: said preparation contains the raw material of following weight proportioning
Hydroquinone 3, arbutin 15, oleuropein 15.
Embodiment 2: said preparation contains the raw material of following weight proportioning
Hydroquinone 3, arbutin 20, oleuropein 10.
Embodiment 3: the freckle effect experiment
Experiment material: the mice that the elegant speckle removing frost in this preparation ointment, spring (Guangzhou U.S. source cosmetics company limited) and Shanghai Slac Experimental Animal Co., Ltd. provide.
Experimental technique: get 60 of mices, be divided at random 3 groups: matched group, smear this preparation ointment group and commercially available speckle removing frost group outward.With depilatory with mouse web portion depilation 48 hours after; get this preparation ointment and commercially available speckle removing frost 0.3g/10g; abdominal part coating 4 times; every minor tick 15 minutes, abdominal part intradermal injection histamine solution 0.02mL then, tail vein injection 1% AZO-blue solution 0.2mL in 2 minutes; after 15 minutes; the cervical vertebra dislocation is put to death, and cuts skin of abdomen open, uses the kind of calliper blued area.
Before and after table 1 liang group mice treatment, blued area relatively
Compare with matched group
△P＜0.05
Zoopery shows, the preparation ointment of making by above-mentioned formula can significance improves the permeability of blood capillary, adjusts microecological balance, blood stasis dispelling and speckle dispelling, treating both the principal and secondary aspects of a disease.Our preclinical study result shows, the treatment group total effective rate is high, and after using, untoward reaction is slight, thereby confirmed the feasibility of said preparation formula.Due to evident in efficacy, untoward reaction is slight, and clinic is used.
Claims (2)
1. treat the external preparation of mottle, it is characterized in that: said preparation contains the raw material of following weight proportioning: hydroquinone 1-5, arbutin 10-20, oleuropein 10-20.
2. a kind of external preparation for the treatment of mottle according to claim 1, it is characterized in that: said preparation contains the raw material of following weight proportioning: hydroquinone 3, arbutin 15, oleuropein 15.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201310057022 CN103110527A (en) | 2013-02-22 | 2013-02-22 | External preparation for spot treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201310057022 CN103110527A (en) | 2013-02-22 | 2013-02-22 | External preparation for spot treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103110527A true CN103110527A (en) | 2013-05-22 |
Family
ID=48408925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201310057022 Pending CN103110527A (en) | 2013-02-22 | 2013-02-22 | External preparation for spot treatment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103110527A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420508A (en) * | 2016-12-05 | 2017-02-22 | 徐州得铸生物科技有限公司 | Amaranthus retroflexus-containing whitening toning lotion |
| CN110585050A (en) * | 2018-06-12 | 2019-12-20 | 科丝美诗株式会社 | Cosmetic composition containing oleuropein for strengthening scalp and improving condition |
-
2013
- 2013-02-22 CN CN 201310057022 patent/CN103110527A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420508A (en) * | 2016-12-05 | 2017-02-22 | 徐州得铸生物科技有限公司 | Amaranthus retroflexus-containing whitening toning lotion |
| CN110585050A (en) * | 2018-06-12 | 2019-12-20 | 科丝美诗株式会社 | Cosmetic composition containing oleuropein for strengthening scalp and improving condition |
| CN110585050B (en) * | 2018-06-12 | 2022-11-08 | 科丝美诗株式会社 | Cosmetic composition containing oleuropein for strengthening scalp and improving condition |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130522 |