CN103006445A - Toothpaste for simultaneously cleaning, whitening and restoring teeth and preparation method of toothpaste - Google Patents
Toothpaste for simultaneously cleaning, whitening and restoring teeth and preparation method of toothpaste Download PDFInfo
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- CN103006445A CN103006445A CN2012105845857A CN201210584585A CN103006445A CN 103006445 A CN103006445 A CN 103006445A CN 2012105845857 A CN2012105845857 A CN 2012105845857A CN 201210584585 A CN201210584585 A CN 201210584585A CN 103006445 A CN103006445 A CN 103006445A
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Abstract
The invention discloses a toothpaste for simultaneously cleaning, whitening and restoring teeth. The toothpaste is prepared from hydroxyapatite, perlite, abrasive agent and acceptable auxiliary material of the toothpaste. According to the toothpaste, the hydroxyapatite and the perlite which are simultaneously contained generate synergistic effects after compounded, oral dirt and bacteria are removed through the abrasive agent, enamel can be restored, and the male and female faces on the surfaces of teeth can be polished so as to achieve the purposes of brightening, cleaning, restoring and whitening the teeth at the same time, the toothpaste is multifunctional and can meet the demands of a great number of consumers. Meanwhile, the invention discloses a preparation method of the toothpaste. The method is simple in process, and the prepared paste has no granulated or air hole phenomenon, and is uniform and stable.
Description
Technical field
The present invention relates to a kind of toothpaste and preparation method thereof, toothpaste of especially a kind of simultaneously cleaning, whitening, reparation tooth and preparation method thereof.
Background technology
Toothpaste is used for cleaning teeth as the most frequently used dental care products, and the protection oral hygiene is a kind of daily necessities to human-body safety.Toothpaste has good oral cavity cleaning ability, and cleansing commonly used in the toothpaste is silicon dioxide and calcium carbonate.In the prior art, the hydroxyapatite of interpolation or perlitic formulation of tooth-paste are also arranged, but just with hydroxyapatite and common silicon dioxide and the toothpaste of calcium carbonate abrasive material composition, the hydroxyapatite of high-load is in use reunited easily because its nanostructured causes it, the mastic of manufacturing produces knot grain, pore phenomenon easily, finally causes the mastic system to be destroyed.The toothpaste that only uses perlite and common silicon dioxide and calcium carbonate abrasive material to form, because perlite is natural product, its impurity still with Lycoperdon polymorphum Vitt, can have a strong impact on the mastic outward appearance through the technique purification in the situation of high-load; And when percentage composition was higher, perlite can have influence on the characteristic of abrasivus, made it produce the dehydration phenomenon, caused the stability that outward appearance is not good even impact is filled a prescription of mastic; And the perlite that existing product is commonly used is amorphous perlite, and the structure corner angle are more together, cause the relative wearing valve of tooth higher, larger to adamantine damage.
To sum up, existing tooth paste product all is only to have cleaning or whitening or repairing effect, can't realize having simultaneously multi-effect, and function ratio is more single, can not satisfy the demand that consumers in general have several functions simultaneously.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art part and a kind of toothpaste that simultaneously tooth is had cleaning, whitening, repair function is provided; Simultaneously, the present invention also provides the preparation method of described toothpaste.
For achieving the above object, the technical scheme that the present invention takes is: a kind of toothpaste that cleans simultaneously whitening reparation tooth, contain the acceptable adjuvant of hydroxyapatite, perlite, abrasivus and toothpaste.
Hydroxyl phosphate in the hydroxyapatite is adamantine chief component composition, and its adding can be repaired dental surface blind crack and slit, reaches firm adamantine effect.Perlitic adding causes that structure can carry out dental surface polishing, and quick tooth-whitening in gentle cleaning oral cavity reaches the effect that improves the dental surface glossiness.Add simultaneously hydroxyapatite and perlite in toothpaste, even unexpected hydroxyapatite and the perlite of finding to use high-load, formed lotion of toothpaste outward appearance still can be accepted by consumer widely.According to dentistry research magazine (Journal ofdental research) (1976) 55(4), the method for testing in 563 has been described and how have been tested tooth and relatively wear away (RDA) relative wear away (REA) with enamel.RDA is relevant with the cleaning capacity of toothpaste, but too high RDA also can damage tooth.At advanced dentistry research (Advanced Dental Research) 11(4) a kind of pellicle cleaning of cleannes has been described than the assessment method of (PCR) among the 576-579.The present invention uses the composite toothpaste of hydroxyl phosphate and perlite, and the significantly decline of its RDA value is found in according to the method described above test and appraisal, and its PCR value even increase.Toothpaste of the present invention, empirical tests has cleaning capacity, compound enamel reparation and polishing whitening two large effects simultaneously, hydroxyapatite has synergism with composite rear its effect of raw material than single use one specific character of perlite, and adamantine repairing effect and whitening ability also have lifting.
As the preferred implementation that cleans simultaneously the toothpaste of whitening reparation tooth of the present invention, by percentage to the quality, the content of described hydroxyapatite is 0.2 ~ 20%, and perlitic content is 0.2 ~ 40%.When hydroxyapatite and perlitic content adopted described proportioning, on the basis that formed mastic is extensively accepted for consumer, gained toothpaste had preferably simultaneously and cleans, repairs, polishes whitening effect.
As the preferred implementation that cleans simultaneously the toothpaste of whitening reparation tooth of the present invention, described hydroxyapatite and perlitic mass ratio are hydroxyapatite: perlite=1:1 ~ 2.5.When hydroxyapatite and perlite adopted described proportioning, this distributed and mixes the agglomeration that can optimize hydroxyapatite, improved the quality and stability of mastic.
As the preferred implementation that cleans simultaneously the toothpaste of whitening reparation tooth of the present invention, the particle diameter of described hydroxyapatite is less than 60nm, and described perlite is laminar, and particle diameter is less than 100 μ m.Its nanostructured of nano level hydroxyapatite itself has stronger adsorption; dirt and the bacterial plaques such as glucosan, sialoprotein that can adsorb dental surface in cleaning oral cavity generate; in cleaning teeth, can play the effect of preventing decayed tooth, further protect enamel.It is laminar that perlite is selected particular configuration, and particle diameter is less than 100 μ m, and its apparent configuration should tend to few corner angle geometries such as circle, and this kind particular configuration is because perlitic corner angle are less, and is lower to the relative wearing valve of tooth, also less to adamantine damage.The perlite of this kind configuration obtains by the method that high temperature puffing cools off again, cooled perlitic structure is fluffy again, density is less and its hardness is larger for high temperature puffing, in the process of oral cavity cleaning, be decomposed into the molecule that certain degree of hardness is arranged in a large number, under the effect of toothbrush, can play the polishing whitening function to the surface of tooth, and not damage enamel.Described high temperature puffing more cooled perlite can be available from World Minerals company, product trade name PerlClean
TM
As the preferred implementation that cleans simultaneously the toothpaste of whitening reparation tooth of the present invention, contain the component of following mass ratio:
As the more preferably embodiment that cleans simultaneously the toothpaste of whitening reparation tooth of the present invention, contain the component of following mass ratio:
As the preferred implementation that cleans simultaneously the toothpaste of whitening reparation tooth of the present invention, described abrasivus is friction-type silicon dioxide; Described thickening agent is thickening type silicon dioxide; Described wetting agent is at least a in Polyethylene Glycol, glycerol and the propylene glycol; Described excipient is at least a in sorbitol, xylitol and the lactose; Described binding agent is at least a in sodium carboxymethyl cellulose, xanthan gum, the carrageenan; Described sweeting agent is at least a in saccharin sodium, sucrose, acesulfame potassium, the sucralose; Described surfactant is at least a in sodium lauryl sulfate, dodecylbenzene sodium sulfonate, amino acid type surfactant and the betaine type amphoteric surfactant.Described water generally adopts deionized water.
Simultaneously, the present invention also provides the preparation method that the toothpaste of tooth is repaired in whitening that cleans simultaneously described above, first with hydroxyapatite and perlite mix homogeneously, and then is mixed into mastic with other components.Hydroxyapatite and perlite are the major function agent in the prescription of toothpaste of the present invention, its large usage quantity, so the homogenizing situation of the two has determined that the outward appearance of mastic characterizes.Hydroxyapatite is easier to occur agglomeration because of its nanostructured, and perlite is loosely organized because of it, bulk density is less, also make its in becoming the glue process difficulty be uniformly dispersed and affect the lotion of toothpaste outward appearance.The inventor is through groping to obtain, and is first that hydroxyapatite and the perlite premixing of aforementioned ratio is even, is mixed into cream with abrasivus etc. again behind its mix homogeneously, can guarantee carrying out smoothly of subsequent technique.
Toothpaste of the present invention, contain simultaneously hydroxyapatite and perlite, remove oral cavity dirt and antibacterial by abrasivus after hydroxyapatite and perlite are compound, except can repairing dental enamel, the dental surface male and fomale(M﹠F) of can also polishing, reach the purpose of polishing brilliant white, therefore, use toothpaste of the present invention, can realize simultaneously the purpose of cleaning, reparation and whitening to tooth, feature richness can satisfy consumers in general's demand.The preparation method of toothpaste of the present invention, technique is simple, and prepared mastic is without knot grain, pore phenomenon, and mastic is uniform and stable.
Description of drawings
Fig. 1 is the microgram of tooth initial surface.
Fig. 2 is for using the microgram of toothpaste of the present invention after 15 days.
Fig. 3 is that different component prescription toothpaste is to the comparison diagram of the cleannes of tooth.
Fig. 4 is that different component prescription toothpaste is to the comparison diagram of the wear intensity of tooth.
Fig. 5 is that different component prescription toothpaste is to the comparison diagram of the polishing degree of tooth.
The specific embodiment
For the purpose, technical solutions and advantages of the present invention better are described, the invention will be further described below in conjunction with the drawings and specific embodiments.
Used perlite all can be available from World Minerals company in following examples, product trade name PerlClean
TM
Embodiment 1
A kind of toothpaste that cleans simultaneously whitening reparation tooth, it contains the component of following mass ratio:
Wherein, described abrasivus is friction-type silicon dioxide; Described thickening agent is thickening type silicon dioxide; Described wetting agent is Polyethylene Glycol; Described excipient is the mixture of sorbitol and xylitol, and the mass ratio of sorbitol and xylitol is 1:1; Described binding agent is sodium carboxymethyl cellulose; Described sweeting agent is the mixture of saccharin sodium and sucrose, and the mass ratio of saccharin sodium and sucrose is 3:1; Described surfactant is sodium lauryl sulfate.
The described toothpaste of present embodiment is prepared from by the following method: first with hydroxyapatite and perlite mix homogeneously, and then be mixed into mastic with other components and get final product.
Embodiment 2
A kind of toothpaste that cleans simultaneously whitening reparation tooth, it contains the component of following mass ratio:
Wherein, described abrasivus is friction-type silicon dioxide; Described thickening agent is thickening type silicon dioxide; Described wetting agent is glycerol; Described excipient is lactose; Described binding agent is the mixture of sodium carboxymethyl cellulose and carrageenan, and the mass ratio of sodium carboxymethyl cellulose and carrageenan is 2:1; Described sweeting agent is sucralose; Described surfactant is amino acid type surfactant.
The described toothpaste of present embodiment is prepared from by the following method: first with hydroxyapatite and perlite mix homogeneously, and then be mixed into mastic with other components and get final product.
Embodiment 3
A kind of toothpaste that cleans simultaneously whitening reparation tooth, it contains the component of following mass ratio:
Wherein, described abrasivus is friction-type silicon dioxide; Described thickening agent is thickening type silicon dioxide; Described wetting agent is the mixture of glycerol and propylene glycol, and the mass ratio of glycerol and propylene glycol is 1:1; Described excipient is the mixture of sorbitol and lactose, and the mass ratio of sorbitol and lactose is 5:1; Described binding agent is xanthan gum; Described sweeting agent is acesulfame potassium; Described surfactant is betaine type amphoteric surfactant.
The described toothpaste of present embodiment is prepared from by the following method: first with hydroxyapatite and perlite mix homogeneously, and then be mixed into mastic with other components and get final product.
Embodiment 4
A kind of toothpaste that cleans simultaneously whitening reparation tooth, it contains the component of following mass ratio:
Wherein, described abrasivus is friction-type silicon dioxide; Described thickening agent is thickening type silicon dioxide; Described wetting agent is the mixture of Polyethylene Glycol, glycerol and propylene glycol, and the mass ratio of Polyethylene Glycol, glycerol and propylene glycol is 1:2:3; Described excipient is the mixture of sorbitol, xylitol and lactose, and the mass ratio of sorbitol, xylitol and lactose is 1:1:2; Described binding agent is carrageenan; Described sweeting agent is the mixture of saccharin sodium, sucrose and acesulfame potassium, and the mass ratio of saccharin sodium, sucrose and acesulfame potassium is 2:1:3; Described surfactant is the mixture of sodium lauryl sulfate and dodecylbenzene sodium sulfonate, and the mass ratio of sodium lauryl sulfate and dodecylbenzene sodium sulfonate is 1:4.
The described toothpaste of present embodiment is prepared from by the following method: first with hydroxyapatite and perlite mix homogeneously, and then be mixed into mastic with other components and get final product.
A kind of toothpaste that cleans simultaneously whitening reparation tooth, it contains the component of following mass ratio:
Wherein, described abrasivus is friction-type silicon dioxide; Described thickening agent is thickening type silicon dioxide; Described wetting agent is propylene glycol; Described excipient is xylitol; Described binding agent is xanthan gum; Described sweeting agent is sucralose; Described surfactant is dodecylbenzene sodium sulfonate.
The described toothpaste of present embodiment is prepared from by the following method: first with hydroxyapatite and perlite mix homogeneously, and then be mixed into mastic with other components and get final product.
Embodiment 6
A kind of toothpaste that cleans simultaneously whitening reparation tooth, it contains the component of following mass ratio:
Wherein, described abrasivus is friction-type silicon dioxide; Described thickening agent is thickening type silicon dioxide; Described wetting agent is the mixture of Polyethylene Glycol and propylene glycol, and the mass ratio of Polyethylene Glycol and propylene glycol is 1:1; Described excipient is lactose; Described binding agent is the mixture of sodium carboxymethyl cellulose and carrageenan, and the mass ratio of sodium carboxymethyl cellulose and carrageenan is 1:3; Described sweeting agent is sucrose; Described surfactant is amino acid type surfactant.
The described toothpaste of present embodiment is prepared from by the following method: first with hydroxyapatite and perlite mix homogeneously, and then be mixed into mastic with other components and get final product.
Embodiment 7
Hydroxyapatite and perlitic mass ratio are on the impact of toothpaste performance
Prepare respectively the toothpaste that 1-5 organizes according to the prescription in the table 1, then detect respectively pH value, fragrance, mastic outward appearance, flatulence and the stability of every group of gained toothpaste.
Table 1 formulation of tooth-paste
| Composition | The 1st group | The 2nd group | The 3rd group | The 4th group | The 5th group |
| Wetting agent | 2~15% | 2~15% | 2~15% | 2~15% | 2~15% |
| Excipient | 15~75% | 15~75% | 15~75% | 15~75% | 15~75% |
| Binding agent | 0.8~1.5% | 0.8~1.5% | 0.8~1.5% | 0.8~1.5% | 0.8~1.5% |
| Sweeting agent | 0.1~0.3% | 0.1~0.3% | 0.1~0.3% | 0.1~0.3% | 0.1~0.3% |
| Hydroxyapatite | 0.2~20% | 0.2~20% | 0.2~20% | 0.2~20% | 0.2~20% |
| Perlite | 0.2~40% | 0.2~40% | 0.2~40% | 0.2~40% | 0.2~40% |
| |
5~20% | 5~20% | 5~20% | 5~20% | 5~20% |
| Thickening agent | 7~10% | 7~10% | 7~10% | 7~10% | 7~10% |
| Surfactant | 1.5~3% | 1.5~3% | 1.5~3% | 1.5~3% | 1.5~3% |
| Essence | 0.8~1.8% | 0.8~1.8% | 0.8~1.8% | 0.8~1.8% | 0.8~1.8% |
| Deionized water | To 100% | To 100% | To 100% | To 100% | To 100% |
| Hydroxyapatite: perlite | 1:0.5 | 1:1 | 1:2 | 1:2.5 | 1:3 |
Detect respectively pH value, fragrance, mastic outward appearance, flatulence and stability according to table 1 gained 1-5 group toothpaste, the result is as shown in table 2.
Table 2 hydroxyapatite and perlitic ratio are on the impact of mastic stability
As seen from Table 2, when hydroxyapatite and perlitic mass ratio are 1:2, mastic stable best.
Embodiment 8
As shown in Figure 1, for not using the microscope enlarged drawing of the dental surface before the toothpaste of the present invention, observe significantly the open small holes of enamel from Fig. 1.In daily life, chew or excess intake acidic materials etc. all can have to the enamel of dental surface wearing and tearing, and be serious even crackle can occur.
Accompanying drawing 2 is to use continuously the dental surface microscope enlarged drawing of toothpaste of the present invention after 15 days; Fig. 2 and Fig. 1 are under the same amplification; can be found to use toothpaste of the present invention after 15 days continuously by Fig. 2, dental surface has covered one deck restoration and protection layer, can't observe adamantine hole.
Contrast by accompanying drawing 1 and accompanying drawing 2 is provable, and toothpaste of the present invention can be repaired the dental surface of wearing and tearing fast.
Embodiment 9
The toothpaste for preparing respectively blank group, matched group 1, matched group 2 and invention group according to following prescription.
Blank group toothpaste contains the component of following mass ratio: friction-type silicon dioxide 20%, and thickening type silicon dioxide 8%, Polyethylene Glycol 6%, sorbitol 35%, sodium carboxymethyl cellulose 1%, sucrose 0.2%, sodium lauryl sulfate 2.5%, essence 1.2%, surplus is water.
Matched group 1 is for replacing to 20% friction-type silicon dioxide in the blank group 2% perlite and 18% friction-type silicon dioxide, all the other compositions and content with blank organize identical.
Matched group 2 replaces to 2% hydroxyapatite and 18% friction-type silicon dioxide with 20% friction-type silicon dioxide in the blank group, and all the other compositions and content are identical with blank group.
The invention group replaces to 0.65% hydroxyapatite, 1.35% perlite and 18% friction-type silicon dioxide with 20% friction-type silicon dioxide in the blank group.
The respectively blank group of contrast, matched group 1, matched group 2 and invention group cleannes (PCR), wear intensity (RDA) and polishing degree, the result respectively as accompanying drawing 3,4,5 and table 3,4,5 shown in.
Table 3 cleannes (PCR) comparing result
| Group | Cleannes (PCR) | Increasing degree ratio (%) |
| Blank group | 109 | - |
| Matched group 1 | 113.5 | 4.13 |
| Matched group 2 | 100 | -8.26 |
| The |
120 | 10.09 |
Can be found out that by table 3 and accompanying drawing 3 the invention group has added simultaneously that hydroxyapatite has added perlite with 1 of perlitic toothpaste and matched group, 2 toothpaste that added hydroxyapatite of matched group are compared, the cleannes of tooth are increased significantly.
Table 4 wear intensity (RDA) comparing result
| Group | Wear intensity (RDA) | Increasing degree ratio (%) |
| Blank group | 210 | - |
| Matched group 1 | 195 | -7.14 |
| Matched group 2 | 190 | -9.52 |
| The invention group | 180 | -11.9 |
Can be found out that by table 4 and accompanying drawing 4 the invention group has added simultaneously that hydroxyapatite has added perlite with 1 of perlitic toothpaste and matched group, 2 toothpaste that added hydroxyapatite of matched group are compared, the wear intensity of tooth is had remarkable reduction.
Can find out that by table 3 and table 4 the invention group is together composite with hydroxyapatite and perlite, its RDA value significantly descends, and significantly improves and play the PCR value, i.e. invention group gained toothpaste has preferably cleaning effect to tooth, and is less to the wearing and tearing of tooth simultaneously.
Table 5 polishing degree comparing result
| Group | The polishing degree | Increasing degree ratio (%) |
| Blank group | 25 | - |
| Matched group 1 | 37 | 48 |
| Matched group 2 | 23 | -8 |
| The invention group | 37 | 48 |
Can be found out by table 5 and accompanying drawing 5,1 of matched group has added perlitic toothpaste and has compared with the blank group, the polishing degree is significantly improved, 2 of matched groups have added the toothpaste of hydroxyapatite and have compared with the blank group, the polishing degree but has decline, and the invention group is added with simultaneously the toothpaste of perlite and hydroxyapatite and compares with matched group 1, but do not descend, but identical.Can illustrate thus in the invention group that hydroxyapatite and perlite have overcome perlite to the impact that tooth polishing degree reduces after composite, still have higher polishing whitening effect.
By table 3-5 and accompanying drawing 3-5 as can be known, hydroxyl phosphate and perlite in the invention group have produced synergism, when improving the toothpaste cleaning effect, can reduce toothpaste to the wearing and tearing of tooth, and have and polish preferably whitening effect.
Last institute should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention but not limiting the scope of the invention; although with reference to preferred embodiment the present invention has been done detailed description; those of ordinary skill in the art is to be understood that; can make amendment or be equal to replacement technical scheme of the present invention, and not break away from essence and the scope of technical solution of the present invention.
Claims (8)
1. one kind is cleaned the toothpaste that tooth is repaired in whitening simultaneously, it is characterized in that, contains the acceptable adjuvant of hydroxyapatite, perlite, abrasivus and toothpaste.
2. the toothpaste that cleans simultaneously whitening reparation tooth as claimed in claim 1 is characterized in that by percentage to the quality, the content of described hydroxyapatite is 0.2 ~ 20%, and perlitic content is 0.2 ~ 40%.
3. as claimed in claim 2ly clean simultaneously the toothpaste that tooth is repaired in whitening, its feature with, described hydroxyapatite and perlitic mass ratio are hydroxyapatite: perlite=1:1 ~ 2.5.
4. the toothpaste that cleans simultaneously whitening reparation tooth as claimed in claim 1 is characterized in that the particle diameter of described hydroxyapatite is less than 60nm, and described perlite is laminar, and particle diameter is less than 100 μ m.
5. the toothpaste that cleans simultaneously whitening reparation tooth as claimed in claim 1 is characterized in that, contains the component of following mass ratio:
6. the toothpaste that cleans simultaneously whitening reparation tooth as claimed in claim 5 is characterized in that, contains the component of following mass ratio:
7. such as claim 5 or the 6 described toothpaste that clean simultaneously whitening reparation tooth, it is characterized in that described abrasivus is friction-type silicon dioxide; Described thickening agent is thickening type silicon dioxide; Described wetting agent is at least a in Polyethylene Glycol, glycerol and the propylene glycol; Described excipient is at least a in sorbitol, xylitol and the lactose; Described binding agent is at least a in sodium carboxymethyl cellulose, xanthan gum, the carrageenan; Described sweeting agent is at least a in saccharin sodium, sucrose, acesulfame potassium, the sucralose; Described surfactant is at least a in sodium lauryl sulfate, dodecylbenzene sodium sulfonate, amino acid type surfactant and the betaine type amphoteric surfactant.
8. one kind is cleaned the preparation method that the toothpaste of tooth is repaired in whitening as claimed in claim 1 simultaneously, it is characterized in that, first with hydroxyapatite and perlite mix homogeneously, and then is mixed into mastic with other components.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107184403A (en) * | 2017-06-22 | 2017-09-22 | 缪来耿 | A kind of toothpaste and preparation method thereof |
| CN107625659A (en) * | 2017-09-04 | 2018-01-26 | 美晨集团股份有限公司 | A kind of whitening toothpaste and preparation method thereof |
| CN108354849A (en) * | 2018-05-08 | 2018-08-03 | 重庆登康口腔护理用品股份有限公司 | A kind of oral care composition and preparation method thereof that cooperation electric toothbrush uses |
| CN111759751A (en) * | 2017-08-03 | 2020-10-13 | 南昌大学 | Whitening toothpaste excited by blue light LED and preparation method thereof |
| CN111888304A (en) * | 2020-09-16 | 2020-11-06 | 白银香生物科技有限公司 | Anti-inflammation and anti-allergy toothpaste and preparation method thereof |
| CN112274441A (en) * | 2020-11-03 | 2021-01-29 | 成都大学 | Tooth polishing paste with whitening self-repairing function and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5597553A (en) * | 1993-01-14 | 1997-01-28 | Hawe Neos Dental Dr H.V. Weissenfluh Ag | Expanded perlite toothpaste |
| CN1429538A (en) * | 2002-01-01 | 2003-07-16 | 孟祥才 | Nano-grade hydroxy apatite, its preparation method and application in toothpaste |
-
2012
- 2012-12-28 CN CN201210584585.7A patent/CN103006445B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5597553A (en) * | 1993-01-14 | 1997-01-28 | Hawe Neos Dental Dr H.V. Weissenfluh Ag | Expanded perlite toothpaste |
| CN1429538A (en) * | 2002-01-01 | 2003-07-16 | 孟祥才 | Nano-grade hydroxy apatite, its preparation method and application in toothpaste |
Non-Patent Citations (2)
| Title |
|---|
| J R MATHESON ET AL: "Effect of toothpaste with natural calcium carbonate/perlite on extrinsic tooth stain", 《INTERNATIONAL DENTAL JOURNAL》 * |
| 姜丽芙: "含有羟基磷灰石和多醇的白牙膏", 《牙膏工业》 * |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107184403A (en) * | 2017-06-22 | 2017-09-22 | 缪来耿 | A kind of toothpaste and preparation method thereof |
| CN111759751A (en) * | 2017-08-03 | 2020-10-13 | 南昌大学 | Whitening toothpaste excited by blue light LED and preparation method thereof |
| CN111759751B (en) * | 2017-08-03 | 2023-03-31 | 南昌大学 | Whitening toothpaste excited by blue light LED and preparation method thereof |
| CN107625659A (en) * | 2017-09-04 | 2018-01-26 | 美晨集团股份有限公司 | A kind of whitening toothpaste and preparation method thereof |
| CN107625659B (en) * | 2017-09-04 | 2020-06-26 | 美晨集团股份有限公司 | Whitening toothpaste and preparation method thereof |
| CN108354849A (en) * | 2018-05-08 | 2018-08-03 | 重庆登康口腔护理用品股份有限公司 | A kind of oral care composition and preparation method thereof that cooperation electric toothbrush uses |
| CN108354849B (en) * | 2018-05-08 | 2021-03-19 | 重庆登康口腔护理用品股份有限公司 | Oral care composition used in cooperation with electric toothbrush and preparation method thereof |
| CN111888304A (en) * | 2020-09-16 | 2020-11-06 | 白银香生物科技有限公司 | Anti-inflammation and anti-allergy toothpaste and preparation method thereof |
| CN112274441A (en) * | 2020-11-03 | 2021-01-29 | 成都大学 | Tooth polishing paste with whitening self-repairing function and preparation method and application thereof |
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| CN103006445B (en) | 2014-10-08 |
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