CN102995402A - Method for solidifying pharmaceutical-grade chitosan oligosaccharide on fabric - Google Patents
Method for solidifying pharmaceutical-grade chitosan oligosaccharide on fabric Download PDFInfo
- Publication number
- CN102995402A CN102995402A CN2012105252419A CN201210525241A CN102995402A CN 102995402 A CN102995402 A CN 102995402A CN 2012105252419 A CN2012105252419 A CN 2012105252419A CN 201210525241 A CN201210525241 A CN 201210525241A CN 102995402 A CN102995402 A CN 102995402A
- Authority
- CN
- China
- Prior art keywords
- chitosan oligosaccharide
- fabric
- solution
- minutes
- bletilla polysaccharide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a method for solidifying pharmaceutical-grade chitosan oligosaccharide on a fabric. The method comprises the following steps of: pouring granular water-soluble chitosan oligosaccharide in water at a normal temperature and uniformly stirring, thus obtaining a chitosan oligosaccharide solution with the concentration of 2% to 5% for later use; mixing and uniformly stirring water and granular water-soluble bletilla striata polysaccharide, thus obtaining a bletilla striata polysaccharide solution with the concentration of 0.5% to 1.5% for later use; stirring the fabric in the prepared chitosan oligosaccharide solution for 20 minutes, soaking the fabric in the chitosan oligosaccharide solution for 30 minutes, and then dehydrating and drying the fabric, wherein the weight ratio of the chitosan oligosaccharide solution to the fabric is equal to 2:1; and stirring the dried fabric in the bletilla striata polysaccharide solution for 10 minutes, soaking the fabric in the bletilla striata polysaccharide solution for 30 minutes, and dehydrating and drying the fabric. The method is simple and flexible in process, the fixation force of the chitosan oligosaccharide is high, and the fabric solidified with the chitosan oligosaccharide can be widely applied to the field of medicines and has the effects of antibiosis, mold prevention, hemostasis and inflammation diminishing.
Description
Technical field
The invention belongs to the fabric treating technical field, be specifically related to a kind ofly with pharmaceutical grade chitosan oligosaccharide finish fabric, and make chitosan oligosaccharide be solidificated in method on the fabric, make fabric have the medicines and health protection effect, rational Application is in field of medicaments.
Background technology
Reader's Digest's Taiwan version in February, 2008 report: since the own war, losing blood seriously is the major reason that causes wounded soldier's death.Even to this day, in Iraq and Afghanistan, still have every day many soldiers because of the death of losing blood.But existing a kind of novel tourniquet bandage emerges at present, and blood (HemCon) bandage that presses down by name is made with the organic substance chitosan oligosaccharide of shrimp and crab shells, can impel blood cell to condense.The bandage of a slice 10 centimeter square can stop the wound that gushes blood in 30 seconds.According to U.S. army's record, in the case of bleeding profusely in the battlefield, the existing use more than ninety percent pressed down the blood bandage and stopped blooding or reduce and bleed.
2003, U.S. army attacked Irak the time, and a special first aid cloth is arranged in soldier's the first-aid dressing, in the time of soldier's wound, this piece cloth one was applied gently at wound, and blood has stopped immediately.This magical first-aid dressing is called as " magical beanbag ".For this magical cloth bag, various countries scientist and military strategist ask about by every possible means, and US military as top-secret military secrecy, is kept one's mouth shut it always.After the war in Iraq finished, this secret ability is visited by other national military secret agent: this was a cloth that soaked with the chitosan oligosaccharide solution of high concentration--press down blood (HemCon) bandage.
One piece of document of publication in " present age healthy newspaper " on March 20th, 2008 " " Chinese Central Television (CCTV) " make every effort to recommend vital principle chitosan oligosaccharide ", the document record: chitosan oligosaccharide also has important physiological hygiene function except the human nutriology plays an important role to human body.Chitosan oligosaccharide at first is to promote hyperplasia to cytosis, by experiment confirm skin, bone, pancreas islet, cardiac muscle, nerve, liver etc. is just arranged.On the other hand cell there is protective effect; can prolong the cell time-to-live in vivo; can also reduce the damage of cell, Cell protection is avoided the damage of various undesirable elements, for the prevention of disease with prevent serious even fatefulue injury is vital.
Chitosan oligosaccharide has the immunity of raising, suppress the cancerous swelling Growth of Cells, promote liver spleen antibody to form, promote the absorption of calcium and mineral matter, human body beneficial's floras such as propagation Bifidobacterium, lactic acid bacteria, reducing blood lipid, hypotensive, hypoglycemic, adjusting cholesterol, fat-reducing, the functions such as prevention AD, social science and technology makes rapid progress now, chitosan oligosaccharide reasonably should be applied to the fields such as medicine, functional food.
Summary of the invention
The above-mentioned technical problem that exists aspect utilizing at chitosan oligosaccharide in order to overcome the prior art field, the object of the invention is to, a kind of method of solidifying the pharmaceutical grade chitosan oligosaccharide at fabric is provided, technique is simple, the chitosan oligosaccharide pull-out capacity is strong, the fabric that is solidified with chitosan oligosaccharide can be widely used in field of medicaments, has the effect of antibacterial and mouldproof, hemostasis and anti-inflammation.
Method of solidifying the pharmaceutical grade chitosan oligosaccharide at fabric provided by the invention may further comprise the steps:
One, prepares: prepare chitosan oligosaccharide solution, get the granular water soluble chitosan oligosaccharide, be poured into water at normal temperatures, stir, make concentration and be 2～5% chitosan oligosaccharide solution for standby; Prepare bletilla polysaccharide solution, at normal temperatures, water and granular water soluble bletilla polysaccharide are mixed, and stir, make the bletilla polysaccharide solution for standby, the concentration of bletilla polysaccharide is 0.5～1.5%;
Two, chitosan oligosaccharide arrangement: with the ready chitosan oligosaccharide solution immersion of step 1, finish fabric, the weight ratio of chitosan oligosaccharide solution and fabric is 2: 1, first fabric is put into chitosan oligosaccharide solution and is stirred 20 minutes, soaks 30 minutes again, dewaters afterwards, dries;
Three, bletilla polysaccharide solidifies: the fabric of step 2 oven dry is put into the ready bletilla polysaccharide solution of step 1 soak, solidify, the weight ratio of bletilla polysaccharide solution and fabric is 4: 1, first fabric is put into bletilla polysaccharide solution and stirred 10 minutes, soaked again 30 minutes, dewater afterwards, dry.
Method of solidifying the pharmaceutical grade chitosan oligosaccharide at fabric provided by the invention, its beneficial effect is, with chitosan oligosaccharide solution fabric is carried out dip-coating, chitosan oligosaccharide permeates inside and outside fabric fibre, thereby improve the characteristic of fabric, change the quality of source textile fiber, given biological fabric active organic molecule, had antibiotic, as to suppress virus infections, hemostasis, anti-inflammatory, anticorrosive, mildew-resistant, promotion wound healing characteristics.Solidify with bletilla polysaccharide solution, can obtain good chitosan oligosaccharide solidification effect, make fabric functional keep lasting.Solidify the method for pharmaceutical grade chitosan oligosaccharide at fabric, maneuverability, cost are low, but to the facing fabric of unlike material all small lot, many kinds carry out processing and sorting production, but processing and sorting is such as tourniquet bandage, hospital gauze etc.
The specific embodiment
Below in conjunction with two embodiment, the method at fabric curing pharmaceutical grade chitosan oligosaccharide provided by the invention is described in detail.
Embodiment one
The method at fabric curing pharmaceutical grade chitosan oligosaccharide of the present embodiment is put in order the finished product gauze, may further comprise the steps:
One, prepares: prepare chitosan oligosaccharide solution, get the granular water soluble chitosan oligosaccharide, be poured into water at normal temperatures, stir, make concentration and be 2% chitosan oligosaccharide solution for standby; Prepare bletilla polysaccharide solution, at normal temperatures, water and granular water soluble bletilla polysaccharide are mixed, and stir, make the bletilla polysaccharide solution for standby, the concentration of bletilla polysaccharide is 0.5%;
Two, chitosan oligosaccharide arrangement: soak, put gauze in order with the ready chitosan oligosaccharide solution of step 1, the weight ratio of chitosan oligosaccharide solution and gauze is 2: 1, first gauze is put into chitosan oligosaccharide solution and is stirred 20 minutes, soaks 30 minutes again, dewaters afterwards, dries;
Three, bletilla polysaccharide solidifies: the gauze of step 2 oven dry is put into the ready bletilla polysaccharide solution of step 1 soak, solidify, the weight ratio of bletilla polysaccharide solution and gauze is 4: 1, first gauze is put into bletilla polysaccharide solution and stirred 10 minutes, soaked again 30 minutes, dewater afterwards, dry.
Embodiment two
One, prepares: prepare chitosan oligosaccharide solution, get granular water soluble chitosan oligosaccharide 3000 grams, pour at normal temperatures in 100 kg of water, stir, make the chitosan oligosaccharide solution for standby; Prepare bletilla polysaccharide solution, at normal temperatures, 200 kg of water and 1500 gram granular water soluble bletilla polysaccharides are mixed, and stir, make the bletilla polysaccharide solution for standby;
Two, chitosan oligosaccharide arrangement: soak, put gauze in order with the ready chitosan oligosaccharide solution of step 1, first 50 kilograms of gauzes are put into chitosan oligosaccharide solution and stirred 20 minutes, soaked again 30 minutes, dewater afterwards, dry;
Three, bletilla polysaccharide solidifies: the gauze of step 2 oven dry is put into the ready bletilla polysaccharide solution of step 1 soak, solidify, first gauze is put into bletilla polysaccharide solution and stirred 10 minutes, soaked 30 minutes again, dewater afterwards, dry.
Practical proof: will solidify the gauze of processing through the dip-coating of pharmaceutical grade chitosan oligosaccharide and bletilla polysaccharide, soak sealing with unboiled water, 25-30 ℃, humidity greater than 80% environment in, carry out mildew test, afterwards unpacking in 10 days, free from extraneous odour still has the characteristics such as good antiviral, hemostasis and anti-inflammation, promotion wound healing.
Claims (1)
1. a method of solidifying the pharmaceutical grade chitosan oligosaccharide at fabric is characterized in that, it may further comprise the steps:
One, prepares: prepare chitosan oligosaccharide solution, get the granular water soluble chitosan oligosaccharide, be poured into water at normal temperatures, stir, make concentration and be 2～5% chitosan oligosaccharide solution for standby; Prepare bletilla polysaccharide solution, at normal temperatures, water and granular water soluble bletilla polysaccharide are mixed, and stir, make the bletilla polysaccharide solution for standby, the concentration of bletilla polysaccharide is 0.5～1.5%;
Two, chitosan oligosaccharide arrangement: with the ready chitosan oligosaccharide solution immersion of step 1, finish fabric, the weight ratio of chitosan oligosaccharide solution and fabric is 2: 1, first fabric is put into chitosan oligosaccharide solution and is stirred 20 minutes, soaks 30 minutes again, dewaters afterwards, dries;
Three, bletilla polysaccharide solidifies: the fabric of step 2 oven dry is put into the ready bletilla polysaccharide solution of step 1 soak, solidify, the weight ratio of bletilla polysaccharide solution and fabric is 4: 1, first fabric is put into bletilla polysaccharide solution and stirred 10 minutes, soaked again 30 minutes, dewater afterwards, dry.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105252419A CN102995402A (en) | 2012-11-17 | 2012-11-17 | Method for solidifying pharmaceutical-grade chitosan oligosaccharide on fabric |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105252419A CN102995402A (en) | 2012-11-17 | 2012-11-17 | Method for solidifying pharmaceutical-grade chitosan oligosaccharide on fabric |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102995402A true CN102995402A (en) | 2013-03-27 |
Family
ID=47924459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012105252419A Pending CN102995402A (en) | 2012-11-17 | 2012-11-17 | Method for solidifying pharmaceutical-grade chitosan oligosaccharide on fabric |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102995402A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103938445A (en) * | 2014-02-25 | 2014-07-23 | 江志清 | Method for processing and finishing ecologic, oxygen permeable and antibiotic mouth mask by using chitosan oligosaccharide |
| CN106012543A (en) * | 2016-07-05 | 2016-10-12 | 无锡嘉加科技有限公司 | Fluoride-free water-repellent antifouling finishing agent and preparation method and application thereof |
| CN108951147A (en) * | 2018-07-17 | 2018-12-07 | 江志清 | Using the method for Biocomposite material improvement fiber |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001069975A (en) * | 1999-09-03 | 2001-03-21 | Hankyu Bio Ind Kk | Chitosanase |
| CN101156868A (en) * | 2007-08-29 | 2008-04-09 | 北京海利安生物科技有限公司 | A bacterium-resisting nursing article |
| CN101781849A (en) * | 2010-01-25 | 2010-07-21 | 江志清 | Method for curing chitosan on fabrics |
-
2012
- 2012-11-17 CN CN2012105252419A patent/CN102995402A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001069975A (en) * | 1999-09-03 | 2001-03-21 | Hankyu Bio Ind Kk | Chitosanase |
| CN101156868A (en) * | 2007-08-29 | 2008-04-09 | 北京海利安生物科技有限公司 | A bacterium-resisting nursing article |
| CN101781849A (en) * | 2010-01-25 | 2010-07-21 | 江志清 | Method for curing chitosan on fabrics |
Non-Patent Citations (2)
| Title |
|---|
| 张芳等: "季铵盐改性壳聚糖/壳寡糖及其在纺织领域的应用", 《纺织科技进展》, no. 01, 25 February 2011 (2011-02-25) * |
| 朱亚伟等: "纺织品抗菌后整理加工现状", 《印染助剂》, no. 01, 31 January 2005 (2005-01-31), pages 10 - 14 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103938445A (en) * | 2014-02-25 | 2014-07-23 | 江志清 | Method for processing and finishing ecologic, oxygen permeable and antibiotic mouth mask by using chitosan oligosaccharide |
| CN106012543A (en) * | 2016-07-05 | 2016-10-12 | 无锡嘉加科技有限公司 | Fluoride-free water-repellent antifouling finishing agent and preparation method and application thereof |
| CN108951147A (en) * | 2018-07-17 | 2018-12-07 | 江志清 | Using the method for Biocomposite material improvement fiber |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110354295B (en) | Photo-thermal conversion material and preparation method thereof | |
| CN105169460B (en) | A kind of magnetic therapy antibacterial anti hemorrhagic dressing and preparation method thereof | |
| CN109432481A (en) | A kind of polyurethane dressing of hemostatic and antibacterial and preparation method thereof | |
| CN103007339B (en) | Biological powder medical dressing and preparation method thereof | |
| Guan et al. | Manufacture of pH-and HAase-responsive hydrogels with on-demand and continuous antibacterial activity for full-thickness wound healing | |
| CN109731121A (en) | A kind of preparation method of the cellulose containing mesoporous silicon oxide and chitosan combine dressing | |
| CN103316377A (en) | Beta-cyclodextrin/carboxymethyl chitosan medical dressing and preparation method thereof | |
| CN102380123B (en) | Collagen membrane medical dressing and preparation method thereof | |
| CN104144692A (en) | Composition, preparation, and use of dense chitosan membrane materials | |
| Yue et al. | Physical dual-network photothermal antibacterial multifunctional hydrogel adhesive for wound healing of drug-resistant bacterial infections synthesized from natural polysaccharides | |
| CN101862469A (en) | Chitosan derivative quick hemostasis granules and preparation method thereof | |
| Zhou et al. | Metal-phenolic self-assembly shielded probiotics in hydrogel reinforced wound healing with antibiotic treatment | |
| Liu et al. | Ultra-stretchable, tissue-adhesive, shape-adaptive, self-healing, on-demand removable hydrogel dressings with multiple functions for infected wound healing in regions of high mobility | |
| Jiang et al. | Carboxymethyl chitosan-based multifunctional hydrogels incorporated with photothermal therapy against drug-resistant bacterial wound infection | |
| CN102995402A (en) | Method for solidifying pharmaceutical-grade chitosan oligosaccharide on fabric | |
| Li et al. | Construction of porous structure-based carboxymethyl chitosan/sodium alginate/tea polyphenols for wound dressing | |
| CN103480032B (en) | A kind of argentiferous plural gel dressing and preparation method thereof | |
| CN104056301A (en) | Traditional Chinese medicine-type hemostatic anti-inflammation liquid bandage and preparation method thereof | |
| Zhang et al. | A wearable self-powered microneedle system based on conductive drugs for infected wound healing: A new electrical stimulation delivery strategy | |
| Zhang et al. | Body temperature-induced adhesive hyaluronate/gelatin-based hybrid hydrogel dressing for promoting skin regeneration | |
| CN105999382A (en) | Chitosan bleeding stopping and pain relieving powder and preparation method thereof | |
| CN102008740B (en) | Absorbable growth factor composite dressing | |
| Bai et al. | Metallic‐Polyphenolic Nanoparticles Reinforced Cationic Guar Gum Hydrogel for Effectively Treating Burn Wound | |
| CN105250333A (en) | Pharmaceutical composition for inhibiting bacteria and nourishing skin and preparation method thereof | |
| CN106729940B (en) | Slow-release long-acting antibacterial silver-loaded dressing and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20130327 |