CN102973615A - Composite capable of enhancing human body immunity - Google Patents
Composite capable of enhancing human body immunity Download PDFInfo
- Publication number
- CN102973615A CN102973615A CN2012104828411A CN201210482841A CN102973615A CN 102973615 A CN102973615 A CN 102973615A CN 2012104828411 A CN2012104828411 A CN 2012104828411A CN 201210482841 A CN201210482841 A CN 201210482841A CN 102973615 A CN102973615 A CN 102973615A
- Authority
- CN
- China
- Prior art keywords
- immunity
- cordyceps militaris
- compositions
- ganoderma
- body immunity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a composite capable of enhancing human body immunity, which contains artificial cordyceps militaris sporocarp and ganoderma lucidum spore powder. Compared with the prior art, the composite disclosed by the invention takes the artificial cordyceps militaris sporocarp as a main material, cordyceps militaris and cordyceps are congeneric and heterogenic and play roles in tonifying kidney yang and lung Qi and resisting pathogens, the two raw materials both have immunity enhancement functions and are both invigorants with higher nutritive values, and the immunity index of a human body can be enhanced and the immunity can be obviously enhanced through the matching use of the two raw materials.
Description
Technical field
The invention belongs to the compositions that strengthens body immunity.
Background technology
Immunity is the function that the antigenicity foreign body was identified and got rid of to body, and namely body is distinguished own and non-own function.Modern medicine study shows: immune system is the important system of human body, and it is comprised of immune organ, immunocyte, immune molecule, is the defensive barrier that human body is resisted disease.When immunity is normal, external pathogenic microorganism is resisted effect, to the aging death cell in the body and other harmful or discommodity, immune system also can be removed.In addition, immune system can initiatively be killed a small amount of mutant cell in the body, prevents that tumor from forming.As seen, keep the immunologic function of normal equilibrium extremely important to health.
Summary of the invention
Technical problem to be solved by this invention provides a kind of compositions of new enhancing body immunity.
The technical scheme of technical solution problem of the present invention is: a kind of compositions that strengthens body immunity, contain the material of following weight portion:
Artificial cordyceps militaris fruiting body 180-210
Ganoderma spore powder 80-100.
Compositions added can to make medicine, health product, animal feed, the percentage by weight of compositions in medicine, health product, animal feed behind the adjuvant be 1-99%.
The dosage form of medicine is drop pill, tablet, capsule, soft capsule, granule, suspensoid, oral liquid, injectable powder, injection, transfusion.
Preferred dosage form is capsule.
Using method of the present invention is: every day 2 times, each 3.
The artificial cordyceps militaris fruiting body: Cordyceps militaris (L.) Link. has another name called Cordyceps militaris, Cordyceps militaris (L.) Link., belongs to xenogenesis together with Cordyceps, has the effect similar to Cordyceps.Cordyceps is the rare Chinese medicine of controlling simply " empty sick hundred decrease ", and the traditional Chinese medical science thinks that nature and flavor are sweet, flat, enter lung, kidney channel, have kidney-replenishing, beneficial marrow, tonifying the lung gas, the function of antiasthmatic-antitussive.The artificial cordyceps militaris fruiting body is rich in the bioactive substances such as Cordyceps polysaccharide, cordycepin, cordycepic acid, and various amino acid whose content are also very abundant, and its content approaches or exceed the content of Cordyceps, has the effect of obvious enhancing immunity.But modern pharmacological research shows the phagocytic function of its enhancing body nonspecific immunity and macrophage, has the important function such as antibiotic, antitumor, enhancing immunity, and health-care effect and natural cordyceps are basically identical, have higher edibility.Modern toxicological experiment studies have shown that artificial cordyceps militaris fruiting body's edible safety is high.This shows that the alternative Cordyceps of artificial cordyceps militaris fruiting body is used for the Application and Development of health food, and artificial Chinese caterpillar fungus being easy to artificial culture, is a kind of good healthy food material.The used artificial cordyceps militaris fruiting body of the present invention is inoculated into the enterprising pedestrian worker of culture medium with Cordyceps militaris (L.) Link. fungus to cultivate, the Cordyceps militaris (L.) Link.sporophore of gathering, steps such as drying and making are accredited as Cordyceps militaris (L.) Link. Cordyceps militaris (L.:Fr.) Link through Institute of Microorganism, Academia Sinica.
The effect of Cordyceps militaris (L.) Link. enhancing immunity is main relevant with polysaccharide, and Cordyceps polysaccharide has obvious activation to reticuloendothelial system and macrophage, can promote lymphocytic conversion, is that a kind of nonspecific immunity strengthens and regulator.Studies show that Cordyceps polysaccharide can improve body body fluid and cell immunocompetent, significantly improve Turnover of Mouse Peritoneal Macrophages phagocytic rate and phagocytic index, improve the body non-specific immunity.
Cordyceps militaris (L.) Link. and Cordyceps belong to xenogenesis together, have similar health care, can invigorating the lung and the kidney, beneficial vital essence etc.Modern pharmacology studies confirm that Cordyceps militaris (L.) Link.sporophore has good enhancing immunity health care, and edible safety.
Ganoderma spore powder: the Ganoderma nature and flavor are sweet, flat, GUIXIN, lung, liver, kidney channel, and Ganoderma on the books in the Shennong's Herbal, and classify it as " top grade ", be the precious tonic that a kind of vital energy benefiting and the kidney invigorating, body-building increase intelligence, strengthening the body resistance, life lengthening.Ganoderma spore is the seed that the Ganoderma development later stage ejects, its chemical constituent has polysaccharide, adenine, nucleoside, adenosine, organic germanium, triterpenes, ergosterol, vitamin, carotene and trace element etc., has the effects such as antitumor, anoxia enduring, raising immunity, antioxidation.Ganoderma spore powder has the whole hereditary active substance of Ganoderma, is the elite of Ganoderma, so Ganoderma spore powder has the effect similar to Ganoderma, and better effects if.The main component of Ganoderma spore powder is polysaccharide.The in recent years health care of Ganoderma spore powder is worth and day by day comes into one's own, and modern study confirms that Ganoderma spore powder has the effect of enhancing human body immunity power.The used Ganoderma spore powder of the present invention is accredited as Ganoderma Ganoderma lucidum (Curtis:Fr) P. Karst through institute of microbiology of the Chinese Academy of Sciences.
Ganoderma spore powder has the whole hereditary active substance of Ganoderma, is the elite of Ganoderma.Ganoderma is the precious tonic that a kind of vital energy benefiting and the kidney invigorating, body-building increase intelligence, strengthening the body resistance, life lengthening, and Ganoderma spore powder has than the better health-care effect of Ganoderma, significantly enhancing human body immunity power.
The present invention compared with prior art, take the artificial cordyceps militaris fruiting body as main, Cordyceps militaris (L.) Link. and Cordyceps belong to xenogenesis together, have similar function.On the traditional Chinese medical science, have kidney-replenishing, tonifying the lung gas, the disease-resistant effect such as former, the artificial cordyceps militaris fruiting body obviously improves the activate the phagocytic capacity of reticuloendothelial system and mononuclear phagocyte, the immunologic function of scalable mice body tissue, can improve body fluid and the cellular immune level of body, enhancing body nonspecific immunity and humoral immune function, the main composition crude polysaccharides of Cordyceps militaris (L.) Link.sporophore can improve body body fluid and cell immunocompetent, significantly improve Turnover of Mouse Peritoneal Macrophages phagocytic rate and phagocytic index, improve the body non-specific immunity.Cordyceps polysaccharide can also significantly strengthen the mice serum antalzyme activity, improves Mouse Liver erythrocyte sod vigor, promotes the erythrocyte garland to form, and can resist the peripheral leukocytes that cyclophosphamide causes and fall now.Be aided with Ganoderma spore powder, Ganoderma spore powder is the elite of Ganoderma, has whole active substances of Ganoderma, has than the better health-care effect of Ganoderma.Ganoderma has the strengthening the body resistance effect on the traditional Chinese medical science, and Ganoderma spore powder has this effect equally; It can improve lymphocyte transformation ability that mice delayed allergy ability, ConA induce, increase the antibody-producting cell number, can obviously strengthen mouse monokaryon macrophage function and the lymphocytic effect of T, and can obviously improve mouse humoral immune and NK cytoactive, have the function of enhancing immunity.Ganoderma spore polysaccharide is the main effective ingredient of Ganoderma spore powder, and it can strengthen arborescent cell, mononuclear phagocyte system and NK cytoactive, but Stimulated Macrophages TNF secretion-β and IL-1 β and produce NO significantly strengthen the phagocytic function of macrophage.Two kinds of raw materials all have the function of enhancing immunity, are the higher tonic of nutritive value, and the two is used, and can improve the immunity of organism index, significantly enhancing immunity.
The specific embodiment
The present invention is described in detail below in conjunction with embodiment.
Artificial cordyceps militaris fruiting body of the present invention buys from the biological company limited of the glad Cordyceps of Tieling cloud
Ganoderma spore powder: buy from Jiangsu Tong Hui bio tech ltd.
Embodiment 1:
Per 1000 (0.35g/ grain) capsules contain following material:
Artificial cordyceps militaris fruiting body 180g
Ganoderma spore powder 80g.
All the other are pharmaceutic adjuvant commonly used.
Embodiment 2:
Per 1000 (0.35g/ grain) capsules contain following material:
Artificial cordyceps militaris fruiting body 200g
Ganoderma spore powder 90g.
Embodiment 3:
Per 1000 (0.35g/ grain) capsules contain following material:
Artificial cordyceps militaris fruiting body 210g
Ganoderma spore powder 100g.
Embodiment 4:
The capsule that embodiment 2 is made is according to the 0.175g/kg.bw(low dosage), dosage among the 0.350g/kg.bw(), the 1.05g/kg.bw(high dose) and the blank group carry out oral 30 days immunity test.
Per 40 mices be one greatly the group, the 1st group is carried out the clearance test of mice carbon;
The 2nd group is carried out the mouse lymphocyte conversion test (mtt assay) that CONA induces;
The 3rd group of mensuration (Jrene improves slide method) of carrying out dirty body ratio measurement, half hemolysis value, antibody-producting cell number
The 4th group is carried out tardy allergy (DTH) (the sufficient sole of the foot thickens method)
The 5th group is carried out Turnover of Mouse Peritoneal Macrophages and engulfs Sanguis Gallus domesticus erythrocyte test (half intracorporal method).
The 6th group of determination of activity (determination of lactate dehydrogenase method) of carrying out the NK cell
Every group of 40 mices are divided into 4 groups at random according to body weight, i.e. low dose group, middle dosage group, high dose group, matched group.
Experiment shows: the 0.175g/kg.bw(low dosage), dosage among the 0.350g/kg.bw(), the 1.05g/kg.bw(high dose) mice NK activity significantly increase (P＜0.001), 1.05/kg.bw(high dose) mice Delayed onset allergy, lymphocyte transformation and carbon clean up ability significantly raise (P＜0.05, P＜0.01).With dosage the ability of weight of mice, antibody-producting cell, semicell haemolysis and macrophage phagocytic chicken red blood cell is showed no obvious impact (P〉0.05).
Claims (4)
1. compositions that strengthens body immunity, contain the material of following weight portion:
Artificial cordyceps militaris fruiting body 180-210
Ganoderma spore powder 80-100.
2. a kind of compositions that strengthens body immunity according to claim 1 is characterized in that: compositions is added can to make medicine, health product, animal feed, the percentage by weight of compositions in medicine, health product, animal feed behind the adjuvant be 1-99%.
3. a kind of compositions that strengthens body immunity according to claim 2, it is characterized in that: the dosage form of described medicine is drop pill, tablet, capsule, soft capsule, granule, suspensoid, oral liquid, injectable powder, injection, transfusion.
4. a kind of compositions that strengthens body immunity according to claim 1 is characterized in that: preferred dosage form is capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104828411A CN102973615A (en) | 2012-11-23 | 2012-11-23 | Composite capable of enhancing human body immunity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104828411A CN102973615A (en) | 2012-11-23 | 2012-11-23 | Composite capable of enhancing human body immunity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102973615A true CN102973615A (en) | 2013-03-20 |
Family
ID=47848150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012104828411A Pending CN102973615A (en) | 2012-11-23 | 2012-11-23 | Composite capable of enhancing human body immunity |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102973615A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103749813A (en) * | 2013-12-25 | 2014-04-30 | 段敬东 | Ganoderma lucidum health tea |
| CN103815406A (en) * | 2014-03-13 | 2014-05-28 | 浙江森芝宝生物科技有限公司 | Ganoderma lucidum, spore and cordyceps composition and preparation method thereof |
| CN105477025A (en) * | 2015-12-23 | 2016-04-13 | 吴军 | Penicillium mycelium composition for improving immunity, as well as preparation and preparation method of penicillium mycelium composition |
| CN106361781A (en) * | 2016-10-28 | 2017-02-01 | 芜湖市诺康生物科技有限公司 | Composition for enhancing immunity and preparation method of composition |
| CN106727738A (en) * | 2016-12-14 | 2017-05-31 | 四川岚晟生物科技有限公司 | A kind of Phellinus glossy ganoderma powder and preparation method thereof |
| CN108057049A (en) * | 2017-12-29 | 2018-05-22 | 贵州苗氏药业股份有限公司 | A kind of Chinese medicine composition for enhancing cell viability and preparation method thereof |
| CN108096625A (en) * | 2017-12-14 | 2018-06-01 | 傅婵 | Antibiotic health care protection pad |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1327852C (en) * | 2002-06-07 | 2007-07-25 | 中国科学院大连化学物理研究所 | A health food possessing immunity regulating function and method for preparing the same |
| CN101073427A (en) * | 2006-05-21 | 2007-11-21 | 张经才 | Glossy ganoderma cordycepin beverage and its production |
| CN101401646A (en) * | 2008-10-20 | 2009-04-08 | 宋福兴 | Soup additive |
| CN102240365A (en) * | 2010-05-14 | 2011-11-16 | 湖南瑞丹科技有限公司 | Pharmaceutical composition for enhancing organism immunity and preparation method thereof |
-
2012
- 2012-11-23 CN CN2012104828411A patent/CN102973615A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1327852C (en) * | 2002-06-07 | 2007-07-25 | 中国科学院大连化学物理研究所 | A health food possessing immunity regulating function and method for preparing the same |
| CN101073427A (en) * | 2006-05-21 | 2007-11-21 | 张经才 | Glossy ganoderma cordycepin beverage and its production |
| CN101401646A (en) * | 2008-10-20 | 2009-04-08 | 宋福兴 | Soup additive |
| CN102240365A (en) * | 2010-05-14 | 2011-11-16 | 湖南瑞丹科技有限公司 | Pharmaceutical composition for enhancing organism immunity and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 《饲料工业》 20090630 何义萍等 "蛹虫草灵芝茶复合饮料的研制" 25-28 1-4 第12卷, 第3期 * |
| 何义萍等: ""蛹虫草灵芝茶复合饮料的研制"", 《饲料工业》 * |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103749813A (en) * | 2013-12-25 | 2014-04-30 | 段敬东 | Ganoderma lucidum health tea |
| CN103815406A (en) * | 2014-03-13 | 2014-05-28 | 浙江森芝宝生物科技有限公司 | Ganoderma lucidum, spore and cordyceps composition and preparation method thereof |
| CN105477025A (en) * | 2015-12-23 | 2016-04-13 | 吴军 | Penicillium mycelium composition for improving immunity, as well as preparation and preparation method of penicillium mycelium composition |
| CN106361781A (en) * | 2016-10-28 | 2017-02-01 | 芜湖市诺康生物科技有限公司 | Composition for enhancing immunity and preparation method of composition |
| CN106727738A (en) * | 2016-12-14 | 2017-05-31 | 四川岚晟生物科技有限公司 | A kind of Phellinus glossy ganoderma powder and preparation method thereof |
| CN108096625A (en) * | 2017-12-14 | 2018-06-01 | 傅婵 | Antibiotic health care protection pad |
| CN108096625B (en) * | 2017-12-14 | 2021-02-09 | 深圳市康乐美科技有限公司 | Antibacterial health-care protective pad |
| CN108057049A (en) * | 2017-12-29 | 2018-05-22 | 贵州苗氏药业股份有限公司 | A kind of Chinese medicine composition for enhancing cell viability and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102973615A (en) | Composite capable of enhancing human body immunity | |
| JP6548520B2 (en) | Insecticide having various effects and production method thereof | |
| CN103445165B (en) | A kind of for product improving sub-health state and combinations thereof thing | |
| CN103860580B (en) | It is a kind of have strengthen the body resistance to consolidate the constitution, the composite fungi amylose preparation of strengthening the spleen and stomach, strengthen immunity function | |
| Pala et al. | Ethnomycological studies of some wild medicinal and edible mushrooms in the Kashmir Himalayas (India) | |
| CN104432035B (en) | The health nutrient composition and method of making the same of enhancing immunity and application | |
| CN101856384B (en) | Liver-protecting combination | |
| CN102948748A (en) | Anti-fatigue health care product | |
| CN109730315A (en) | A kind of rhizoma polygonati edible mushroom oral solution and preparation method thereof that is antifatigue, improving immunity | |
| CN106616587A (en) | Selenium-containing product for improving physical strength and resisting fatigue and preparation method and application thereof | |
| CN103622017B (en) | Glossy ganoderma cordycepin particle | |
| CN103932180B (en) | A kind ofly to release the pressure and the health food of antifatigue and two-step fermentation preparation method thereof | |
| CN102670669A (en) | Anti-cancer, anti-virus, anti-fatigue kidney-tonifying selenium-enriched Chinese caterpillar fungus powder and capsule | |
| CN102813199A (en) | Health-care food for prevention and adjuvant therapy of cancer, three-high disease and immunity strengthening | |
| CN105213456A (en) | A kind of anti-fatigue medicament and its production and use | |
| CN104056054B (en) | The oral formulations of a kind of anti-oxidant and strengthen immunity and its preparation | |
| CN103932179B (en) | A kind of health food and two-step fermentation preparation method thereof releasing the pressure and protect liver | |
| CN103550399A (en) | Health-care food for relieving physical fatigue, and preparation method thereof | |
| CN105661491A (en) | Peach gum health-care product and preparation method and application thereof | |
| CN103622027B (en) | A kind of hypoglycemia healthcare food composition | |
| CN104906140A (en) | Donkey-hide gelatin, a preparation method and associated equipment | |
| CN104224909A (en) | Health-care granules with immune modulating function and preparation method of health-care granules | |
| CN104757667A (en) | Beverage and preparation method thereof | |
| CN102885313A (en) | Anti-fatigue health care product | |
| CN101244047B (en) | Application of octacosanol in preparing medicament for preventing and controlling altitude erythrocytosis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20130320 |