CN102727596A - Chinese medicinal granula for preventing and controlling coccidiosis in chicken and preparation method thereof - Google Patents

Chinese medicinal granula for preventing and controlling coccidiosis in chicken and preparation method thereof Download PDF

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CN102727596A
CN102727596A CN2012102487709A CN201210248770A CN102727596A CN 102727596 A CN102727596 A CN 102727596A CN 2012102487709 A CN2012102487709 A CN 2012102487709A CN 201210248770 A CN201210248770 A CN 201210248770A CN 102727596 A CN102727596 A CN 102727596A
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chinese medicine
omphalia
radix
medicinal powder
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CN102727596B (en
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刘睿芬
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Tianjin Shengji Group Co Ltd
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Tianjin Shengji Group Co Ltd
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Abstract

The invention provides a Chinese medicinal granula for preventing and controlling coccidiosis in chickens and a preparation method of the Chinese medicinal granula. The Chinese granula is prepared from the following raw materials by weight: 2-5 parts of pumpkin seed, 1-4 parts of fruit of rangoon creeper, 1-2 parts of stone-like omphalia and 1-2 parts of rheum officinale, by the steps of decocting and mixing with auxiliary materials. The Chinese medicinal granula is based on reasonable proportioning of traditional Chinese medicines, is a medicine with effective treatment effect on coccidiosis in chicken and has the characteristics of quick acting, definite treatment effect, no residue and no toxic or side effect. The preparation method is simple and meets the requirement of large-scale industrial production.

Description

A kind of Chinese medicine granules of preventing and treating chicken coccidiosis and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine granules and preparation method thereof, especially a kind of Chinese medicine granules of preventing and treating chicken coccidiosis and preparation method thereof.
Background technology
Chicken coccidiosis is an Enterozoa protozoacide common during modern intensiveization is raised chickens, and this disease sickness rate is 50%~70%, and mortality rate is more than 80%, and hazardness is very big, has caused great economic loss to aquaculture.And the chickling of recovering often is difficult for getting well in the several months, and becoming chicken is the carrier mostly, and growth and egg laying performance are all had very big influence, and other poultry such as duck, turkey, Columba livia, Carnis Coturnicis japonicae etc. all can infect this disease, are seriously threatening the development of China's birds aquaculture.Yet the control present stage for this disease does not still have effective method, therefore utilizes the Chinese material medicine resource of China's abundant, through Chinese medicine is rationally screened and prescription, researches and develops a kind of newtype drug of preventing and treating chicken coccidiosis and has very important production practices meaning.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine granules of preventing and treating chicken coccidiosis.
Another technical problem to be solved by this invention is to provide the method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine granules of preventing and treating chicken coccidiosis is made up of Semen Cucurbitae, Fructus Quisqualis, Omphalia and Radix Et Rhizoma Rhei, by its parts by weight Semen Cucurbitae 2-5 part, Fructus Quisqualis 1-4 part, Omphalia 1-2 part, Radix Et Rhizoma Rhei 1-2 part.
Preferably, the Chinese medicine granules of above-mentioned control chicken coccidiosis is by its parts by weight Semen Cucurbitae 3-4 part, Fructus Quisqualis 2-3 part, Omphalia 1-1.5 part, Radix Et Rhizoma Rhei 1-1.5 part
Preferably, the Chinese medicine granules of above-mentioned control chicken coccidiosis, by 3 parts of its parts by weight Semen Cucurbitaes, 3 parts of Fructus Quisqualis, 1 part of Omphalia, 1 part of Radix Et Rhizoma Rhei.
Preferably, the Chinese medicine granules of above-mentioned control chicken coccidiosis is obtained by following method:
(1) taking by weighing Semen Cucurbitae, Fructus Quisqualis, Omphalia, Radix Et Rhizoma Rhei by weight is raw material, mix homogeneously;
(2) in above-mentioned four flavor Chinese medicines, add the water that medical material gross weight 10-20 doubly measures, decoct 2 times, decocted 1.0-2.0 hour for the first time, decocted 1.0-2.0 hour for the second time, collecting decoction, filtrating was left standstill 12-36 hour, filtered;
(3) gained is filtrated under 60-80 ℃ of condition, be concentrated into relative density 1.1-1.5, pulverize the oven dry back under the 60-70 ℃ of condition, obtains medicinal powder;
(4) in medicinal powder, add the sucrose mixing, process granule with 70%-95% (v/v) ethanol and cross the 10-30 mesh sieve, under 50-90 ℃ of condition, dry,, promptly get after the 10-30 mesh sieve.
The method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, concrete preparation process is following:
(1) taking by weighing Semen Cucurbitae 2-5 part, Fructus Quisqualis 1-4 part, Omphalia 1-2 part, Radix Et Rhizoma Rhei 1-2 part by weight is raw material, mix homogeneously;
(2) in above-mentioned four flavor Chinese medicines, add the water that medical material gross weight 10-20 doubly measures, decoct 2 times, decocted 1.0-2.0 hour for the first time, decocted 1.0-2.0 hour for the second time, collecting decoction, filtrating was left standstill 12-36 hour, filtered;
(3) gained is filtrated under 60-80 ℃ of condition, be concentrated into relative density 1.1-1.5, pulverize the oven dry back under the 60-70 ℃ of condition, obtains medicinal powder;
(4) in medicinal powder, add the sucrose mixing, process granule with 70%-95% (v/v) ethanol and cross the 10-30 mesh sieve, under 50-90 ℃ of condition, dry,, promptly get after the 10-30 mesh sieve.
Preferably, the method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, concrete preparation process is following:
(1) take by weighing 3 parts of Semen Cucurbitaes by weight, 3 parts of Fructus Quisqualis, 1 part of Omphalia, Radix Et Rhizoma Rhei is a raw material for 1 part, mix homogeneously;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time, decocted 1.5 hours for the second time, and collecting decoction, filtrating was left standstill 24 hours, filtered;
(3) gained is filtrated in being concentrated into oven dry back pulverizing under 1.28,65 ℃ of conditions of relative density under 80 ℃ of conditions, obtain medicinal powder;
(4) in medicinal powder, add the sucrose mixing, process granule with 85% (v/v) ethanol and cross 20 mesh sieves, under 60 ℃ of conditions, dry,, promptly get after 30 mesh sieves.
Preferably, the method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, the weight ratio of said step (4) medicinal powder and sucrose is 10:6-8.
Preferably, the method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, the weight ratio of said step (4) medicinal powder and sucrose is 10:7.
Above-mentioned relative density is meant the proportion of this filtrating.
The consumption of the Chinese medicine granules of above-mentioned control chicken coccidiosis lets chicken freely drink for adding mixing in the 1000kg water by every 3g Chinese medicine granules, and logotype 3~5 days was a course of treatment.
The invention has the beneficial effects as follows:
The Chinese medicine granules of above-mentioned control chicken coccidiosis, with the Chinese medicine reasonable formula, for aquaculture provides a kind of effective medicine of chicken coccidiosis, have instant effect, curative effect really, no drug residue, characteristics without any side effects; Its preparation method is simple, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment technical scheme according to the invention is further described.
Embodiment 1
A kind of Chinese medicine granules of preventing and treating chicken coccidiosis is made up of Semen Cucurbitae, Fructus Quisqualis, Omphalia and Radix Et Rhizoma Rhei, wherein Semen Cucurbitae 3kg, Fructus Quisqualis 3kg, Omphalia 1kg, Radix Et Rhizoma Rhei 1kg.
The method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, concrete preparation process is following:
(1) taking by weighing Semen Cucurbitae 3kg, Fructus Quisqualis 3kg, Omphalia 1kg, Radix Et Rhizoma Rhei 1kg is raw material, mix homogeneously;
(2) water (80kg) of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time, decocted 1.5 hours for the second time, and collecting decoction, filtrating was left standstill 24 hours, filtered;
(3) gained is filtrated in being concentrated into oven dry back pulverizing under 1.28,65 ℃ of conditions of relative density under 80 ℃ of conditions, obtain medicinal powder;
(4) in medicinal powder, add the sucrose mixing, the weight ratio of wherein said medicinal powder and sucrose is 10:7, processes granule with 85% (v/v) ethanol and crosses 20 mesh sieves, under 60 ℃ of conditions, dries, and after 30 mesh sieves, promptly gets.
Embodiment 2
A kind of Chinese medicine granules of preventing and treating chicken coccidiosis is made up of Semen Cucurbitae, Fructus Quisqualis, Omphalia and Radix Et Rhizoma Rhei, wherein Semen Cucurbitae 2kg, Fructus Quisqualis 4kg, Omphalia 2kg, Radix Et Rhizoma Rhei 2kg.
The method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, concrete preparation process is following:
(1) taking by weighing Semen Cucurbitae 2kg, Fructus Quisqualis 4kg, Omphalia 2kg, Radix Et Rhizoma Rhei 2kg is raw material, mix homogeneously;
(2) water of 20 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time, decocted 1.0 hours for the second time, and collecting decoction, filtrating was left standstill 12 hours, filtered;
(3) gained is filtrated in being concentrated into oven dry back pulverizing under 1.5,60 ℃ of conditions of relative density under 80 ℃ of conditions, obtain medicinal powder;
(4) in medicinal powder, add the sucrose mixing, the weight ratio of wherein said medicinal powder and sucrose is 10:6, processes granule with 95% (v/v) ethanol and crosses 10 mesh sieves, under 50 ℃ of conditions, dries, and after 10 mesh sieves, promptly gets.
Embodiment 3
A kind of Chinese medicine granules of preventing and treating chicken coccidiosis is made up of Semen Cucurbitae, Fructus Quisqualis, Omphalia and Radix Et Rhizoma Rhei, wherein Semen Cucurbitae 5kg, Fructus Quisqualis 1kg, Omphalia 1kg, Radix Et Rhizoma Rhei 1kg.
The method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, concrete preparation process is following:
(1) taking by weighing Semen Cucurbitae 5kg, Fructus Quisqualis 1kg, Omphalia 1kg, Radix Et Rhizoma Rhei 1kg is raw material, mix homogeneously;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 1.0 hours for the first time, decocted 2.0 hours for the second time, and collecting decoction, filtrating was left standstill 36 hours, filtered;
(3) gained is filtrated in being concentrated into oven dry back pulverizing under 1.1,70 ℃ of conditions of relative density under 60 ℃ of conditions, obtain medicinal powder;
(4) in medicinal powder, add the sucrose mixing, the weight ratio of wherein said medicinal powder and sucrose is 10:8, processes granule with 70% (v/v) ethanol and crosses 30 mesh sieves, under 90 ℃ of conditions, dries, and after 30 mesh sieves, promptly gets.
Embodiment 4
A kind of Chinese medicine granules of preventing and treating chicken coccidiosis is made up of Semen Cucurbitae, Fructus Quisqualis, Omphalia and Radix Et Rhizoma Rhei, wherein Semen Cucurbitae 4kg, Fructus Quisqualis 2kg, Omphalia 1.5kg, Radix Et Rhizoma Rhei 1.5kg.
The method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, concrete preparation process is following:
(1) taking by weighing Semen Cucurbitae 4kg, Fructus Quisqualis 2kg, Omphalia 1.5kg, Radix Et Rhizoma Rhei 1.5kg is raw material, mix homogeneously;
(2) water of 15 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 1.5 hours for the first time, decocted 1.5 hours for the second time, and collecting decoction, filtrating was left standstill 18 hours, filtered;
(3) gained is filtrated in being concentrated into oven dry back pulverizing under 1.3,65 ℃ of conditions of relative density under 75 ℃ of conditions, obtain medicinal powder;
(4) in medicinal powder, add the sucrose mixing, the weight ratio of wherein said medicinal powder and sucrose is 10:7.5, processes granule with 75% (v/v) ethanol and crosses 20 mesh sieves, under 75 ℃ of conditions, dries, and after 20 mesh sieves, promptly gets.
Embodiment 5
A kind of Chinese medicine granules of preventing and treating chicken coccidiosis is made up of Semen Cucurbitae, Fructus Quisqualis, Omphalia and Radix Et Rhizoma Rhei, wherein Semen Cucurbitae 2.5kg, Fructus Quisqualis 3.5kg, Omphalia 2kg, Radix Et Rhizoma Rhei 1kg.
The method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, concrete preparation process is following:
(1) taking by weighing Semen Cucurbitae 2.5kg, Fructus Quisqualis 3.5kg, Omphalia 2kg, Radix Et Rhizoma Rhei 1kg is raw material, mix homogeneously;
(2) water of 18 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time, decocted 2.0 hours for the second time, and collecting decoction, filtrating was left standstill 30 hours, filtered;
(3) gained is filtrated in being concentrated into oven dry back pulverizing under 1.2,67 ℃ of conditions of relative density under 70 ℃ of conditions, obtain medicinal powder;
(4) in medicinal powder, add the sucrose mixing, the weight ratio of wherein said medicinal powder and sucrose is 10:6.5, processes granule with 90% (v/v) ethanol and crosses 30 mesh sieves, under 85 ℃ of conditions, dries, and after 20 mesh sieves, promptly gets.
Embodiment 6
A kind of Chinese medicine granules of preventing and treating chicken coccidiosis is made up of Semen Cucurbitae, Fructus Quisqualis, Omphalia and Radix Et Rhizoma Rhei, wherein Semen Cucurbitae 3.5kg, Fructus Quisqualis 1.5kg, Omphalia 1.2kg, Radix Et Rhizoma Rhei 1.7kg.
The method for preparing of the Chinese medicine granules of above-mentioned control chicken coccidiosis, concrete preparation process is following:
(1) taking by weighing Semen Cucurbitae 3.5kg, Fructus Quisqualis 1.5kg, Omphalia 1.2kg, Radix Et Rhizoma Rhei 1.7kg is raw material, mix homogeneously;
(2) water of 12 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 1.5 hours for the first time, decocted 1.2 hours for the second time, and collecting decoction, filtrating was left standstill 20 hours, filtered;
(3) gained is filtrated in being concentrated into oven dry back pulverizing under 1.4,65 ℃ of conditions of relative density under 70 ℃ of conditions, obtain medicinal powder;
(4) in medicinal powder, add the sucrose mixing, the weight ratio of wherein said medicinal powder and sucrose is 10:7, processes granule with 70% (v/v) ethanol and crosses 20 mesh sieves, under 70 ℃ of conditions, dries, and after 20 mesh sieves, promptly gets.
The said Chinese crude drug of one of embodiment 1-6 is the commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The said Chinese crude drug of embodiment 1-6 all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2010.
The composition principle of Chinese medicine oral liquid according to the invention is: Semen Cucurbitae parasite killing in the side; The Fructus Quisqualis killing insect and eliminating accumulation; The Omphalia killing insect and eliminating accumulation; The Radix Et Rhizoma Rhei heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body; All medicines share, and Synergistic is remarkably productive to the control chicken coccidiosis each other, especially adopts embodiment 1 said proportioning, and anthelmintic, removing heat from blood, antidotal effect are very remarkable, particularly are fit to the control of chicken coccidiosis.
The clinical trial example:
The consumption of the Chinese medicine granules of above-mentioned control chicken coccidiosis lets chicken freely drink for adding mixing in the 1000kg water by every 3g Chinese medicine granules, and logotype 4 days was a course of treatment.Oral back absorbs the purpose that reaches the treatment disease through gastrointestinal.
In June, 2010, the raise chickens chicken morbidity of 2500 50 ages in days that specialist raises of Hebei, clinical symptoms: sick chicken essence god is depressed, and feather is fluffy; Head is crispaturaed, loss of appetite, full of liquid in the crop, cockscomb and visual mucosa anemia, pale; Become thin gradually, sick chicken is often arranged red Radix Dauci Sativae appearance feces, is with blood in the feces; And contain the intestinal mucosa that comes off in a large number, and 15 death are arranged, be diagnosed as chicken coccidiosis.Then treat with embodiment 1 said Chinese medicine granules, the medication 4 back state of an illness are controlled, do not occur dead again; After one week, sick chicken transfers to normally, and showing as feed intake increases, and red Radix Dauci Sativae appearance feces no longer occurs, is not with blood in the feces, feather gloss, and spirit is good.
Above-mentioned detailed description of this a kind of Chinese medicine granules of preventing and treating chicken coccidiosis and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.

Claims (8)

1. a Chinese medicine granules of preventing and treating chicken coccidiosis is characterized in that: be made up of Semen Cucurbitae, Fructus Quisqualis, Omphalia and Radix Et Rhizoma Rhei, by its parts by weight Semen Cucurbitae 2-5 part, Fructus Quisqualis 1-4 part, Omphalia 1-2 part, Radix Et Rhizoma Rhei 1-2 part.
2. the Chinese medicine granules of control chicken coccidiosis according to claim 1 is characterized in that: by its parts by weight Semen Cucurbitae 3-4 part, Fructus Quisqualis 2-3 part, Omphalia 1-1.5 part, Radix Et Rhizoma Rhei 1-1.5 part.
3. the Chinese medicine granules of control chicken coccidiosis according to claim 2 is characterized in that: by 3 parts of its parts by weight Semen Cucurbitaes, and 3 parts of Fructus Quisqualis, 1 part of Omphalia, 1 part of Radix Et Rhizoma Rhei.
4. according to the Chinese medicine granules of the described control chicken coccidiosis of one of claim 1-3, it is characterized in that: obtain by following method:
(1) taking by weighing Semen Cucurbitae, Fructus Quisqualis, Omphalia, Radix Et Rhizoma Rhei by weight is raw material, mix homogeneously;
(2) in above-mentioned four flavor Chinese medicines, add the water that medical material gross weight 10-20 doubly measures, decoct 2 times, decocted 1.0-2.0 hour for the first time, decocted 1.0-2.0 hour for the second time, collecting decoction, filtrating was left standstill 12-36 hour, filtered;
(3) gained is filtrated under 60-80 ℃ of condition, be concentrated into relative density 1.1-1.5, pulverize the oven dry back under the 60-70 ℃ of condition, obtains medicinal powder;
(4) in medicinal powder, add the sucrose mixing, process granule with 70%-95% (v/v) ethanol and cross the 10-30 mesh sieve, under 50-90 ℃ of condition, dry,, promptly get after the 10-30 mesh sieve.
5. the method for preparing of the Chinese medicine granules of the described control chicken coccidiosis of claim 1 is characterized in that: concrete preparation process is following:
(1) taking by weighing Semen Cucurbitae 2-5 part, Fructus Quisqualis 1-4 part, Omphalia 1-2 part, Radix Et Rhizoma Rhei 1-2 part by weight is raw material, mix homogeneously;
(2) in above-mentioned four flavor Chinese medicines, add the water that medical material gross weight 10-20 doubly measures, decoct 2 times, decocted 1.0-2.0 hour for the first time, decocted 1.0-2.0 hour for the second time, collecting decoction, filtrating was left standstill 12-36 hour, filtered;
(3) gained is filtrated under 60-80 ℃ of condition, be concentrated into relative density 1.1-1.5, pulverize the oven dry back under the 60-70 ℃ of condition, obtains medicinal powder;
(4) in medicinal powder, add the sucrose mixing, process granule with 70%-95% (v/v) ethanol and cross the 10-30 mesh sieve, under 50-90 ℃ of condition, dry,, promptly get after the 10-30 mesh sieve.
6. the method for preparing of the Chinese medicine granules of control chicken coccidiosis according to claim 5 is characterized in that: concrete preparation process is following:
(1) take by weighing 3 parts of Semen Cucurbitaes by weight, 3 parts of Fructus Quisqualis, 1 part of Omphalia, Radix Et Rhizoma Rhei is a raw material for 1 part, mix homogeneously;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time, decocted 1.5 hours for the second time, and collecting decoction, filtrating was left standstill 24 hours, filtered;
(3) gained is filtrated in being concentrated into oven dry back pulverizing under 1.28,65 ℃ of conditions of relative density under 80 ℃ of conditions, obtain medicinal powder;
(4) in medicinal powder, add the sucrose mixing, process granule with 85% (v/v) ethanol and cross 20 mesh sieves, under 60 ℃ of conditions, dry,, promptly get after 30 mesh sieves.
7. according to the method for preparing of the Chinese medicine granules of claim 5 or 6 described control chicken coccidiosis, it is characterized in that: the weight ratio of said step (4) medicinal powder and sucrose is 10:6-8.
8. the method for preparing of the Chinese medicine granules of control chicken coccidiosis according to claim 7 is characterized in that: the weight ratio of said step (4) medicinal powder and sucrose is 10:7.
CN201210248770.9A 2012-07-18 2012-07-18 A kind of Chinese herbal granules for preventing chicken coccidiasis and preparation method thereof Active CN102727596B (en)

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Publication number Priority date Publication date Assignee Title
CN103623071A (en) * 2013-12-03 2014-03-12 湖北武当动物药业有限责任公司 Powerful insect repellent for veterinary use and preparation method thereof
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CN116474014B (en) * 2023-04-28 2024-06-04 河北锦坤动物药业有限公司 Traditional Chinese medicine composition for treating chicken histomonas and preparation method thereof

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