CN102707000A - 参仙灵颗粒中人参皂苷Rg1含量的测定方法 - Google Patents
参仙灵颗粒中人参皂苷Rg1含量的测定方法 Download PDFInfo
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- CN102707000A CN102707000A CN2012100656030A CN201210065603A CN102707000A CN 102707000 A CN102707000 A CN 102707000A CN 2012100656030 A CN2012100656030 A CN 2012100656030A CN 201210065603 A CN201210065603 A CN 201210065603A CN 102707000 A CN102707000 A CN 102707000A
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- water
- ginsenoside
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- liquid
- methanol
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- YURJSTAIMNSZAE-UHFFFAOYSA-N UNPD89172 Natural products C1CC(C2(CC(C3C(C)(C)C(O)CCC3(C)C2CC2O)OC3C(C(O)C(O)C(CO)O3)O)C)(C)C2C1C(C)(CCC=C(C)C)OC1OC(CO)C(O)C(O)C1O YURJSTAIMNSZAE-UHFFFAOYSA-N 0.000 title claims abstract description 29
- YURJSTAIMNSZAE-HHNZYBFYSA-N ginsenoside Rg1 Chemical compound O([C@@](C)(CCC=C(C)C)[C@@H]1[C@@H]2[C@@]([C@@]3(C[C@@H]([C@H]4C(C)(C)[C@@H](O)CC[C@]4(C)[C@H]3C[C@H]2O)O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)C)(C)CC1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YURJSTAIMNSZAE-HHNZYBFYSA-N 0.000 title claims abstract description 29
- CBEHEBUBNAGGKC-UHFFFAOYSA-N ginsenoside Rg1 Natural products CC(=CCCC(C)(OC1OC(CO)C(O)C(O)C1O)C2CCC3(C)C2C(O)CC4C5(C)CCC(O)C(C)(C)C5CC(OC6OC(CO)C(O)C(O)C6O)C34C)C CBEHEBUBNAGGKC-UHFFFAOYSA-N 0.000 title claims abstract description 29
- 238000000034 method Methods 0.000 title claims abstract description 23
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- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 66
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 42
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims abstract description 38
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims abstract description 19
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract description 15
- 239000000284 extract Substances 0.000 claims abstract description 12
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- PBCJIPOGFJYBJE-UHFFFAOYSA-N acetonitrile;hydrate Chemical compound O.CC#N PBCJIPOGFJYBJE-UHFFFAOYSA-N 0.000 claims abstract description 4
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- 229930182494 ginsenoside Natural products 0.000 description 3
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- ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 description 1
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- 210000000865 mononuclear phagocyte system Anatomy 0.000 description 1
- YTJSFYQNRXLOIC-UHFFFAOYSA-N octadecylsilane Chemical compound CCCCCCCCCCCCCCCCCC[SiH3] YTJSFYQNRXLOIC-UHFFFAOYSA-N 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
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Abstract
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Application Number | Priority Date | Filing Date | Title |
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CN201210065603.0A CN102707000B (zh) | 2012-03-14 | 2012-03-14 | 参仙灵颗粒中人参皂苷Rg1含量的测定方法 |
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CN201210065603.0A CN102707000B (zh) | 2012-03-14 | 2012-03-14 | 参仙灵颗粒中人参皂苷Rg1含量的测定方法 |
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CN102707000A true CN102707000A (zh) | 2012-10-03 |
CN102707000B CN102707000B (zh) | 2015-02-04 |
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CN201210065603.0A Expired - Fee Related CN102707000B (zh) | 2012-03-14 | 2012-03-14 | 参仙灵颗粒中人参皂苷Rg1含量的测定方法 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110187022A (zh) * | 2019-05-21 | 2019-08-30 | 贵州联盛药业有限公司 | 一种参倍固肠胶囊中人参皂苷Re含量的测定方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63193039A (ja) * | 1987-02-06 | 1988-08-10 | Shimadzu Corp | 朝鮮ニンジンの薬効成分分析方法 |
CA2434050A1 (en) * | 2000-12-22 | 2002-08-01 | Tianjin Tasly Pharmaceutical Co., Ltd., China | Herbal composition for angina pectoris, method to prepare same and uses thereof |
-
2012
- 2012-03-14 CN CN201210065603.0A patent/CN102707000B/zh not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63193039A (ja) * | 1987-02-06 | 1988-08-10 | Shimadzu Corp | 朝鮮ニンジンの薬効成分分析方法 |
CA2434050A1 (en) * | 2000-12-22 | 2002-08-01 | Tianjin Tasly Pharmaceutical Co., Ltd., China | Herbal composition for angina pectoris, method to prepare same and uses thereof |
Non-Patent Citations (3)
Title |
---|
孟舒等: "高效液相色谱法测定玄丹巴布剂中三七皂苷R1和人参皂苷Rg1含量", 《中国医院药学杂志》, vol. 29, no. 12, 30 June 2009 (2009-06-30) * |
洗少华等: "HPLC法测定胃痞消颗粒中3种皂苷的含量", 《西北药学杂志》, vol. 26, no. 2, 1 April 2011 (2011-04-01) * |
苏静等: "RP-HPLC梯度洗脱法测定血塞通片中三七皂苷R1、人参皂苷Rb1及人参皂苷Rg1的含量", 《药物分析杂志》, vol. 25, no. 2, 28 February 2005 (2005-02-28) * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110187022A (zh) * | 2019-05-21 | 2019-08-30 | 贵州联盛药业有限公司 | 一种参倍固肠胶囊中人参皂苷Re含量的测定方法 |
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Effective date of registration: 20200416 Address after: No. 34, No. 34, yanggongjing, Qinhuai District, Nanjing, Jiangsu 210002 Patentee after: Qinhuai medical area, General Hospital of the eastern theater of the Chinese PLA Address before: Yang Gong Jing Baixia District of Nanjing city in Jiangsu province 210002 34 Standard No. 34 Bayi hospital pharmacy Co-patentee before: Lan Xiaohong Patentee before: Zhou Yonggang Co-patentee before: Wei Wei |
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