CN102698226A - 一种治疗带状疱疹后遗神经痛的中药 - Google Patents
一种治疗带状疱疹后遗神经痛的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗带状疱疹后遗神经痛的中药，由以下重量配比的药材制备而成：柴胡10-20份，葛根10-20份，羌活10-20份，芍药10-20份，白芷10-20份，桔梗10-20份，筋骨草10-20份，黄芩10-20份，石膏10-20份，生姜20-30份，大枣20-30份。实验证明，本发明的药能够安全有效治疗带状疱疹后遗神经痛。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗带状疱疹后遗神经痛的中药。
背景技术
带状疱疹后遗神经痛就是带状疱疹遗留下来的疼痛，属于后遗症的一种。临床上认为带状疱疹的皮疹消退以后，其局部皮肤仍有疼痛不适，且持续1个月以上者称为带状疱疹后遗神经痛，即PHN。表现为局部阵发性或持续性的灼痛、刺痛、跳痛、刀割痛，严重者影响了休息、睡眠、精神状态等。目前治疗采用药物有较大的毒副作用，成本高，治愈率低，在治疗效果方面不能令人满意。因此研究开发一种安全有效地治疗带状疱疹后遗神经痛的中药非常有价值。
本发明中药所涉及药材的研究现状如下：
柴胡：【来源】 本品为伞形科植物柴胡Bupleurum chinense DC.或狭叶柴胡Bupleurum scorzonerifolium Willd.的干燥根。【功能主治】 和解表里，疏肝，升阳。用于感冒发热，寒热往来，胸胁胀痛，***，子官脱垂，脱肛。
葛根：【来源】 本品为豆科植物野葛Pueraria lobata （Willd.）Ohwi或甘葛藤Pueraria thomsonii Benth.的干燥根。【功能主治】 解肌退热，生津，透疹，升阳止泻。用于外感发热头痛、项背强痛，口渴，消渴，麻疹不透，热痢，泄泻；高血压颈项强痛。
羌活：【来源】 本品为伞形科植物羌活（背翅芹）Notopterygium incisum Ting ex H. T. Chang 或宽叶羌活Notopterygium forbesii Boiss. 的干燥根茎及根。【功能主治】 散寒，祛风，除湿，止痛。用于风寒感冒头痛，风湿痹痛，肩背酸痛。
芍药：【来源】 本品为毛茛科植物芍药Paeonia lactiflora Pall. 的干燥根。【功能主治】 平肝止痛，养血调经，敛阴止汗。用于头痛眩晕，胁痛，腹痛，四肢挛痛，血虚萎黄，***，自汗，盗汗。
白芷：【来源】 本品为伞型科植物白芷Angelica dahurica （Fisch.ex Hoffm.） Benth. et Hook.f.或杭白芷Angelica dahurica（Fisch.ex Hoffm.） Benth.et Hook.f. var.formosana（Boiss.）Shan et Yuan 的干燥根。【功能主治】 散风除湿，通窍止痛，消肿排脓。用于感冒头痛，眉棱骨痛，鼻塞，鼻渊，牙痛，白带，疮疡肿痛。
桔梗：【来源】 本品为桔梗科桔梗属植物桔梗(Platycodon grandiforus)干燥的根。功能主治：宣肺，利咽，祛痰，排脓。用于咳嗽痰多，胸闷不畅，音哑，肺痈吐脓，疮疡脓成不溃。
筋骨草：【来源】唇形科筋骨草属植物筋骨草Ajuga decumbens Thunb.的全草。【功能主治】清热解毒，凉血平肝。用于上呼吸道感染，扁桃体炎，咽炎，支气管炎，肺炎，肺脓疡，胃肠炎，肝炎，阑尾炎，乳腺炎，急性结膜炎，高血压；外用治跌打损伤，外伤出血，痈疖疮疡，烧烫伤，毒蛇咬伤。
黄芩：【来源】 本品为唇形科植物黄芩Scutellaria baicalensis Georgi的干燥根。【功能主治】 清热燥湿，泻火解毒，止血，安胎。用于湿温、暑温胸闷呕恶，湿热痞满，泻痢，黄疸，肺热咳嗽，高热烦渴，血热吐衄，痈肿疮毒，胎动不安。
石膏：【来源】 本品为硫酸盐类矿物硬石膏族石膏。【功能主治】 清热泻火，除烦止渴。用于外感热病，高热烦渴，肺热喘咳，胃火亢盛，头痛，牙痛。
生姜：【来源】 本品为姜科植物姜Zingiber officinale Rosc.的新鲜根茎。【功能主治】 解表散寒，温中止呕，化痰止咳。用于风寒感冒，胃寒呕吐，寒痰咳嗽。
大枣：来源】 本品为鼠李科枣属植物枣Ziziphus jujuba Mill. var. inermis （Bunge） Rehd. 的干燥成熟果实。【功能主治】补中益气，养血安神。用于脾虚食少，乏力便溏，妇人脏躁。
发明内容
本发明旨在提供一种治疗带状疱疹后遗神经痛的中药，通过选择合适的药材及其配比，达到安全有效治愈带状疱疹后遗神经痛的目的。
为了达到上述目的，本发明采用以下技术方案：一种治疗带状疱疹后遗神经痛的中药，其特征在于，由以下重量配比的药材制备而成：柴胡10-20份，葛根10-20份，羌活10-20份，芍药10-20份，白芷10-20份，桔梗10-20份，筋骨草10-20份，黄芩10-20份，石膏10-20份，生姜20-30份，大枣20-30份。
其中优选：
柴胡15份，葛根15份，羌活15份，芍药15份，白芷15份，桔梗15份，筋骨草15份，黄芩15份，石膏15份，生姜25份，大枣25份。
下面结合中医理论说明本发明的有益效果：
发明人在实践过程中发现，带状疱疹后遗神经痛证属邪遏经络，气郁化热。头左侧前额部疼痛，四肢倦怠，汗出不桑，大便干结，肌肉阵痛。本发明运用柴胡，葛根，羌活，芍药，白芷，桔梗，筋骨草，黄芩，石膏，生姜，大枣，综合作用从而有效地治疗带状疱疹后遗神经痛。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2008年9月-2012年3月间共收集75例带状疱疹后遗神经痛的门诊患者，其中男37例，女38例，年龄16-75岁，病程1月-1年。随机分为：治疗组50例，对照组25例。两组性别、年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1对照组采用口服牛黄消炎片 ，常规剂量每天3次。疗程2周。
2.2治疗组采用口服本发明中药优选配方按照具体实施例1制成的药品，早晚各一次。疗程2周。
2.3观察项目：疼痛次数，疼痛程度等。观察三个月有无反复。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) |
| 治疗组 | 50 | 38(76%) | 10（20%) | 2(4%) | 96% |
| 对照组 | 25 | 2(8%) | 16(64%) | 7(28%) | 72% |
可见，本发明优选实施方式制得的药物是能够安全有效治疗带状疱疹后遗神经痛的中药。
根据上述临床实验数据，结合本发明治疗带状疱疹后遗神经痛的中医学机理分析和本领域公知常识，本领域技术人员容易推知，运用本发明中的药材，在最佳重量份附近取值，至少在“柴胡10-20份，葛根10-20份，羌活10-20份，芍药10-20份，白芷10-20份，桔梗10-20份，筋骨草10-20份，黄芩10-20份，石膏10-20份，生姜20-30份，大枣20-30份”的范围内，可以取得与本发明优选实施方式制得的药物类似的技术效果。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取柴胡10克，葛根10克，羌活10克，芍药10克，白芷10克，桔梗10克，筋骨草10克，黄芩10克，石膏10克，生姜20克，大枣20克加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成年人一天用量的胶囊剂。
用于治疗带状疱疹后遗神经痛。口服，每日分早晚两次服用。
具体实施例2
称取柴胡15克，葛根15克，羌活15克，芍药15克，白芷15克，桔梗15克，筋骨草15克，黄芩15克，石膏15克，生姜25克，大枣25克加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，包装，即得符合正常老年人一天用量的散剂。
用于治疗带状疱疹后遗神经痛。口服，每日分早中晚3次服用。
具体实施例3
称取柴胡20克，葛根20克，羌活20克，芍药20克，白芷20克，桔梗20克，筋骨草20克，黄芩20克，石膏20克，生姜30克，大枣30克加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常老年人一天用量的颗粒剂。
用于治疗带状疱疹后遗神经痛。口服，每日分早中晚3次服用。
Claims (2)
1.一种治疗带状疱疹后遗神经痛的中药，其特征在于，由以下重量配比的药材制备而成：柴胡10-20份，葛根10-20份，羌活10-20份，芍药10-20份，白芷10-20份，桔梗10-20份，筋骨草10-20份，黄芩10-20份，石膏10-20份，生姜20-30份，大枣20-30份。
2.按照权利要求1所述的一种治疗带状疱疹后遗神经痛的中药组合物，其特征在于，，由以下重量配比的药材制备而成：柴胡10-20份，葛根15份，羌活15份，芍药15份，白芷15份，桔梗15份，筋骨草15份，黄芩15份，石膏115份，生姜25份，大枣25份。
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103212025A (zh) * | 2013-04-06 | 2013-07-24 | 衣翠红 | 一种治疗带状疱疹后遗神经痛的中药制剂 |
| CN104840662A (zh) * | 2015-04-28 | 2015-08-19 | 黄静 | 一种治疗带状疱疹的中药外涂剂 |
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| 李艳红: "中医药治疗带状疱疹临床研究进展", 《实用中医内科杂志》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103212025A (zh) * | 2013-04-06 | 2013-07-24 | 衣翠红 | 一种治疗带状疱疹后遗神经痛的中药制剂 |
| CN104840662A (zh) * | 2015-04-28 | 2015-08-19 | 黄静 | 一种治疗带状疱疹的中药外涂剂 |
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